3300026863_4 - 7 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00016_3300026.. (original name was: 3300026863.a:Ga0209902_100013)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	terpene	214,855	235,688

c00022_3300026.. (original name was: 3300026863.a:Ga0209902_100167)

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	T3PKS	59,665	100,576

c00027_3300026.. (original name was: 3300026863.a:Ga0209902_100097)

Region	Type	From	To	Most similar known cluster		Similarity
Region 27.1	NRPS,transAT-PKS	1	150,140

c00029_3300026.. (original name was: 3300026863.a:Ga0209902_100511)

Region	Type	From	To	Most similar known cluster		Similarity
Region 29.1	lanthipeptide	1	15,926

c00031_3300026.. (original name was: 3300026863.a:Ga0209902_100004)

Region	Type	From	To	Most similar known cluster		Similarity
Region 31.1	terpene	499,686	520,840

c00048_3300026.. (original name was: 3300026863.a:Ga0209902_100049)

Region	Type	From	To	Most similar known cluster		Similarity
Region 48.1	bacteriocin	33,495	44,649
Region 48.2	other,T1PKS	91,422	170,930

Region	Type	From	To	Similarity
Region 16.1	terpene	214,855	235,688
Region 22.1	T3PKS	59,665	100,576
Region 27.1	NRPS,transAT-PKS	1	150,140
Region 29.1	lanthipeptide	1	15,926
Region 31.1	terpene	499,686	520,840
Region 48.1	bacteriocin	33,495	44,649
Region 48.2	other,T1PKS	91,422	170,930

No secondary metabolite regions were found in these records:: c00001_3300026.. (original name was: 3300026863.a:Ga0209902_101820); c00002_3300026.. (original name was: 3300026863.a:Ga0209902_102821); c00003_3300026.. (original name was: 3300026863.a:Ga0209902_100204); c00004_3300026.. (original name was: 3300026863.a:Ga0209902_100115); c00005_3300026.. (original name was: 3300026863.a:Ga0209902_100066); c00006_3300026.. (original name was: 3300026863.a:Ga0209902_100027); c00007_3300026.. (original name was: 3300026863.a:Ga0209902_100096); c00008_3300026.. (original name was: 3300026863.a:Ga0209902_100707); c00009_3300026.. (original name was: 3300026863.a:Ga0209902_100035); c00010_3300026.. (original name was: 3300026863.a:Ga0209902_100045); c00011_3300026.. (original name was: 3300026863.a:Ga0209902_100286); c00012_3300026.. (original name was: 3300026863.a:Ga0209902_100092); c00013_3300026.. (original name was: 3300026863.a:Ga0209902_100053); c00014_3300026.. (original name was: 3300026863.a:Ga0209902_100100); c00015_3300026.. (original name was: 3300026863.a:Ga0209902_100585); c00017_3300026.. (original name was: 3300026863.a:Ga0209902_100710); c00018_3300026.. (original name was: 3300026863.a:Ga0209902_100839); c00019_3300026.. (original name was: 3300026863.a:Ga0209902_100080); c00020_3300026.. (original name was: 3300026863.a:Ga0209902_100178); c00021_3300026.. (original name was: 3300026863.a:Ga0209902_100345); c00023_3300026.. (original name was: 3300026863.a:Ga0209902_100246); c00024_3300026.. (original name was: 3300026863.a:Ga0209902_100200); c00025_3300026.. (original name was: 3300026863.a:Ga0209902_100076); c00026_3300026.. (original name was: 3300026863.a:Ga0209902_100388); c00028_3300026.. (original name was: 3300026863.a:Ga0209902_100026); c00030_3300026.. (original name was: 3300026863.a:Ga0209902_100198); c00032_3300026.. (original name was: 3300026863.a:Ga0209902_100180); c00033_3300026.. (original name was: 3300026863.a:Ga0209902_100133); c00034_3300026.. (original name was: 3300026863.a:Ga0209902_100315); c00035_3300026.. (original name was: 3300026863.a:Ga0209902_100509); c00036_3300026.. (original name was: 3300026863.a:Ga0209902_100215); c00037_3300026.. (original name was: 3300026863.a:Ga0209902_100894); c00038_3300026.. (original name was: 3300026863.a:Ga0209902_100118); c00039_3300026.. (original name was: 3300026863.a:Ga0209902_100179); c00040_3300026.. (original name was: 3300026863.a:Ga0209902_100847); c00041_3300026.. (original name was: 3300026863.a:Ga0209902_101720); c00042_3300026.. (original name was: 3300026863.a:Ga0209902_100062); c00043_3300026.. (original name was: 3300026863.a:Ga0209902_100430); c00044_3300026.. (original name was: 3300026863.a:Ga0209902_100323); c00045_3300026.. (original name was: 3300026863.a:Ga0209902_100517); c00046_3300026.. (original name was: 3300026863.a:Ga0209902_100093); c00047_3300026.. (original name was: 3300026863.a:Ga0209902_100069); c00049_3300026.. (original name was: 3300026863.a:Ga0209902_100534); c00050_3300026.. (original name was: 3300026863.a:Ga0209902_102156); c00051_3300026.. (original name was: 3300026863.a:Ga0209902_100022); c00052_3300026.. (original name was: 3300026863.a:Ga0209902_100119); c00053_3300026.. (original name was: 3300026863.a:Ga0209902_100272); c00054_3300026.. (original name was: 3300026863.a:Ga0209902_100175); c00055_3300026.. (original name was: 3300026863.a:Ga0209902_100501)

Compact view

c00027_3300026.. - Region 1 - NRPS,transAT-PKS

Download region GenBank file

Location: 1 - 150,140 nt. (total: 150,140 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
transAT-PKS: (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 150140:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (lys - orn - gln) + (gln) + (X) + (X - X) + (X) + (X - X) + (X) + (X) + (asp - X) + (asp) + (ohmal) + (asp) + (lys) + (leu) + (ala - ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg27_11

Search NORINE for peptide: strict or relaxed

CAL_domain (96..537): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 200.6
NH2: 3.2
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1191..1581): lys

NRPSPredictor2: lys

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DtESIGtVCK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 80% (moderate)

AMP-binding (2240..2645): orn

NRPSPredictor2: orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEIGSIDK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 100% (strong)

AMP-binding (3301..3700): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAQDLGVVnK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 90% (moderate)

ctg27_12

Search NORINE for peptide: strict or relaxed

AMP-binding (260..659): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAQDLGVVDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 100% (strong)

ctg27_18

Search NORINE for peptide: strict or relaxed

AMP-binding (184..394): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: --Ea--LfaK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 30% (weak)

CAL_domain (610..1045): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 18.3
NH2: 0.3
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1779..2184): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DlWnFGGVyK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 70% (weak)

ctg27_21

Search NORINE for peptide: strict or relaxed

AMP-binding (9..440): X

NRPSPredictor2: pro, pip

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DArHLaLmiK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 60% (weak)

AMP-binding (1097..1525): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DArHLaLLaK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 70% (weak)

ctg27_23

Search NORINE for peptide: strict or relaxed

AMP-binding (12..442): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DArHLsLmiK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 60% (weak)

ctg27_24

Search NORINE for peptide: strict or relaxed

AMP-binding (10..439): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DArHLaLLaK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 70% (weak)

AMP-binding (1102..1531): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DArHLaLLaK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 70% (weak)

ctg27_25

Search NORINE for peptide: strict or relaxed

AMP-binding (9..437): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DArHLaLLaK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 70% (weak)

ctg27_30

Search NORINE for peptide: strict or relaxed

AMP-binding (1..429): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DArHLaLLaK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 70% (weak)

ctg27_32

Search NORINE for peptide: strict or relaxed

AMP-binding (462..866): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHIGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

AMP-binding (1524..1934): X

NRPSPredictor2: hydrophobic-aromatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiWeVtAddK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 50% (weak)

ctg27_33

Search NORINE for peptide: strict or relaxed

AMP-binding (458..863): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKlGHIGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 90% (moderate)

ctg27_37

Search NORINE for peptide: strict or relaxed

AMP-binding (260..663): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKlGHIGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 90% (moderate)

ctg27_38

PKS_AT (6..292): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 92.2
Methoxymalonyl-CoA: 43.0
inactive: 33.6
Methylmalonyl-CoA: 31.0
Ethylmalonyl-CoA: 15.1
Propionyl-CoA: 14.2
CHC-CoA: 14.1
Acetyl-CoA: 10.7
fatty_acid: 9.8
trans-1,2-CPDA: 0.0
Isobutyryl-CoA: 0.0
Benzoyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 62.5%

ctg27_39

Search NORINE for peptide: strict or relaxed

AMP-binding (1811..2203): lys

NRPSPredictor2: lys

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DtESIGtVCK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 80% (moderate)

ctg27_40

Search NORINE for peptide: strict or relaxed

AMP-binding (43..435): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

ctg27_41

Search NORINE for peptide: strict or relaxed

AMP-binding (263..651): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

AMP-binding (1312..1697): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

c00029_3300026.. - Region 1 - lanthipeptide

Download region GenBank file

Location: 1 - 15,926 nt. (total: 15,926 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135))) and not (YcaO or TIGR03882))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Lanthipeptides

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

c00048_3300026.. - Region 2 - T1PKS,other

Download region GenBank file

Location: 91,422 - 170,930 nt. (total: 79,509 nt) Show pHMM detection rules used

other: (LmbU or Neocarzinostat or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 91421 - 170930:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 123631 - 170930:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg48_122

PKS_AT (555..853): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 104.1
Methoxymalonyl-CoA: 91.7
Ethylmalonyl-CoA: 85.7
Isobutyryl-CoA: 82.1
Malonyl-CoA: 77.6
trans-1,2-CPDA: 66.1
Acetyl-CoA: 58.7
2-Methylbutyryl-CoA: 54.9
Propionyl-CoA: 53.2
Benzoyl-CoA: 49.9
fatty_acid: 39.8
CHC-CoA: 33.5
inactive: 21.3
3-Methylbutyryl-CoA: 19.8

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; CE-Malonyl-CoA: 66.7%; Methylmalonyl-CoA: 66.7%