3300026897_2 - 16 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00007_3300026.. (original name was: 3300026897.a:Ga0209906_100056)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	terpene	73,084	94,052

c00012_3300026.. (original name was: 3300026897.a:Ga0209906_100128)

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	NRPS	1	58,366

c00022_3300026.. (original name was: 3300026897.a:Ga0209906_100037)

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	bacteriocin	85,472	95,675
Region 22.2	NRPS,betalactone	192,300	254,341

c00024_3300026.. (original name was: 3300026897.a:Ga0209906_100157)

Region	Type	From	To	Most similar known cluster		Similarity
Region 24.1	microviridin	41,062	61,313

c00030_3300026.. (original name was: 3300026897.a:Ga0209906_100046)

Region	Type	From	To	Most similar known cluster		Similarity
Region 30.1	lassopeptide	1	17,818
Region 30.2	bacteriocin	83,324	93,557

c00032_3300026.. (original name was: 3300026897.a:Ga0209906_100287)

Region	Type	From	To	Most similar known cluster		Similarity
Region 32.1	terpene	16,480	33,054

c00033_3300026.. (original name was: 3300026897.a:Ga0209906_100005)

Region	Type	From	To	Most similar known cluster		Similarity
Region 33.1	terpene	216,575	237,405
Region 33.2	NRPS,T1PKS	641,526	731,496

c00039_3300026.. (original name was: 3300026897.a:Ga0209906_100070)

Region	Type	From	To	Most similar known cluster		Similarity
Region 39.1	NRPS	19,123	77,293

c00043_3300026.. (original name was: 3300026897.a:Ga0209906_100017)

Region	Type	From	To	Most similar known cluster		Similarity
Region 43.1	NRPS	210,508	257,287
Region 43.2	terpene	400,523	421,458

c00053_3300026.. (original name was: 3300026897.a:Ga0209906_100053)

Region	Type	From	To	Most similar known cluster		Similarity
Region 53.1	T1PKS	1	24,278
Region 53.2	hglE-KS,T1PKS	118,825	171,730

c00054_3300026.. (original name was: 3300026897.a:Ga0209906_100058)

Region	Type	From	To	Most similar known cluster		Similarity
Region 54.1	hglE-KS,T1PKS	32,387	84,431

Region	Type	From	To	Similarity
Region 7.1	terpene	73,084	94,052
Region 12.1	NRPS	1	58,366
Region 22.1	bacteriocin	85,472	95,675
Region 22.2	NRPS,betalactone	192,300	254,341
Region 24.1	microviridin	41,062	61,313
Region 30.1	lassopeptide	1	17,818
Region 30.2	bacteriocin	83,324	93,557
Region 32.1	terpene	16,480	33,054
Region 33.1	terpene	216,575	237,405
Region 33.2	NRPS,T1PKS	641,526	731,496
Region 39.1	NRPS	19,123	77,293
Region 43.1	NRPS	210,508	257,287
Region 43.2	terpene	400,523	421,458
Region 53.1	T1PKS	1	24,278
Region 53.2	hglE-KS,T1PKS	118,825	171,730
Region 54.1	hglE-KS,T1PKS	32,387	84,431

No secondary metabolite regions were found in these records:: c00001_3300026.. (original name was: 3300026897.a:Ga0209906_101325); c00002_3300026.. (original name was: 3300026897.a:Ga0209906_100651); c00003_3300026.. (original name was: 3300026897.a:Ga0209906_100529); c00004_3300026.. (original name was: 3300026897.a:Ga0209906_100137); c00005_3300026.. (original name was: 3300026897.a:Ga0209906_100094); c00006_3300026.. (original name was: 3300026897.a:Ga0209906_100191); c00008_3300026.. (original name was: 3300026897.a:Ga0209906_100369); c00009_3300026.. (original name was: 3300026897.a:Ga0209906_100621); c00010_3300026.. (original name was: 3300026897.a:Ga0209906_100039); c00011_3300026.. (original name was: 3300026897.a:Ga0209906_100274); c00013_3300026.. (original name was: 3300026897.a:Ga0209906_100055); c00014_3300026.. (original name was: 3300026897.a:Ga0209906_100149); c00015_3300026.. (original name was: 3300026897.a:Ga0209906_100127); c00016_3300026.. (original name was: 3300026897.a:Ga0209906_100733); c00017_3300026.. (original name was: 3300026897.a:Ga0209906_100480); c00018_3300026.. (original name was: 3300026897.a:Ga0209906_100057); c00019_3300026.. (original name was: 3300026897.a:Ga0209906_100365); c00020_3300026.. (original name was: 3300026897.a:Ga0209906_100610); c00021_3300026.. (original name was: 3300026897.a:Ga0209906_100319); c00023_3300026.. (original name was: 3300026897.a:Ga0209906_100065); c00025_3300026.. (original name was: 3300026897.a:Ga0209906_100042); c00026_3300026.. (original name was: 3300026897.a:Ga0209906_100050); c00027_3300026.. (original name was: 3300026897.a:Ga0209906_100144); c00028_3300026.. (original name was: 3300026897.a:Ga0209906_100096); c00029_3300026.. (original name was: 3300026897.a:Ga0209906_100049); c00031_3300026.. (original name was: 3300026897.a:Ga0209906_100143); c00034_3300026.. (original name was: 3300026897.a:Ga0209906_100302); c00035_3300026.. (original name was: 3300026897.a:Ga0209906_100279); c00036_3300026.. (original name was: 3300026897.a:Ga0209906_100091); c00037_3300026.. (original name was: 3300026897.a:Ga0209906_100067); c00038_3300026.. (original name was: 3300026897.a:Ga0209906_100164); c00040_3300026.. (original name was: 3300026897.a:Ga0209906_100215); c00041_3300026.. (original name was: 3300026897.a:Ga0209906_100095); c00042_3300026.. (original name was: 3300026897.a:Ga0209906_100192); c00044_3300026.. (original name was: 3300026897.a:Ga0209906_100299); c00045_3300026.. (original name was: 3300026897.a:Ga0209906_100119); c00046_3300026.. (original name was: 3300026897.a:Ga0209906_100061); c00047_3300026.. (original name was: 3300026897.a:Ga0209906_100172); c00048_3300026.. (original name was: 3300026897.a:Ga0209906_100138); c00049_3300026.. (original name was: 3300026897.a:Ga0209906_100041); c00050_3300026.. (original name was: 3300026897.a:Ga0209906_100066); c00051_3300026.. (original name was: 3300026897.a:Ga0209906_100068); c00052_3300026.. (original name was: 3300026897.a:Ga0209906_100100)

Compact view

c00007_3300026.. - Region 1 - terpene

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Location: 73,084 - 94,052 nt. (total: 20,969 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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c00012_3300026.. - Region 1 - NRPS

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Location: 1 - 58,366 nt. (total: 58,366 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 58366:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-ile) + (pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg12_17

Search NORINE for peptide: strict or relaxed

AMP-binding (478..899): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVhFIclLvK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 60% (weak)

ctg12_25

Search NORINE for peptide: strict or relaxed

AMP-binding (1816..2220): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

c00022_3300026.. - Region 1 - bacteriocin

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Location: 85,472 - 95,675 nt. (total: 10,204 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

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core biosynthetic genes

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c00022_3300026.. - Region 2 - NRPS,betalactone

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Location: 192,300 - 254,341 nt. (total: 62,042 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 192299 - 254341:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (phe - D-X) + (leu) + (val - X) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg22_176

Search NORINE for peptide: strict or relaxed

AMP-binding (46..438): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAWtIAAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 90% (moderate)

AMP-binding (1121..1527): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DtEdIGSViK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 70% (weak)

ctg22_177

Search NORINE for peptide: strict or relaxed

AMP-binding (481..885): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAlFLGaVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 80% (moderate)

ctg22_178

Search NORINE for peptide: strict or relaxed

AMP-binding (511..931): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

AMP-binding (1592..1983): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DlgFgGcAtK
Nearest Stachelhaus code:: pip
Stachelhaus code match:: 50% (weak)

ctg22_179

Search NORINE for peptide: strict or relaxed

AMP-binding (541..942): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DlaFtGCVnK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

c00024_3300026.. - Region 1 - microviridin

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Location: 41,062 - 61,313 nt. (total: 20,252 nt) Show pHMM detection rules used

microviridin: (mvd or mvnA)

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c00030_3300026.. - Region 1 - lassopeptide

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Location: 1 - 17,818 nt. (total: 17,818 nt) Show pHMM detection rules used

Region on contig edge.

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

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Lasso peptides

Lasso peptide predictions

Lassopeptides - No core peptides found.

Lasso peptides

Core peptide predictions

No core peptides found.

c00030_3300026.. - Region 2 - bacteriocin

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Location: 83,324 - 93,557 nt. (total: 10,234 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

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c00032_3300026.. - Region 1 - terpene

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Location: 16,480 - 33,054 nt. (total: 16,575 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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c00033_3300026.. - Region 1 - terpene

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Location: 216,575 - 237,405 nt. (total: 20,831 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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c00033_3300026.. - Region 2 - NRPS,T1PKS

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Location: 641,526 - 731,496 nt. (total: 89,971 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 641525 - 731496:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala) + (ohmal) + (asn) + (D-X) + (X) + (X) + (ohmal) + (D-X) + (D-X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg33_582

Search NORINE for peptide: strict or relaxed

AMP-binding (467..867): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGhVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

ctg33_583

Search NORINE for peptide: strict or relaxed

AMP-binding (509..926): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVedIGAVEK
Nearest Stachelhaus code:: arg
Stachelhaus code match:: 80% (moderate)

ctg33_584

PKS_AT (539..833): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 87.5%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 168.4
inactive: 111.4
Methoxymalonyl-CoA: 67.2
Methylmalonyl-CoA: 61.9
Ethylmalonyl-CoA: 31.0
Propionyl-CoA: 30.7
Isobutyryl-CoA: 30.0
Benzoyl-CoA: 29.5
2-Methylbutyryl-CoA: 26.0
CHC-CoA: 21.3
Acetyl-CoA: 14.8
fatty_acid: 11.8
trans-1,2-CPDA: 9.5
3-Methylbutyryl-CoA: 7.3

ctg33_585

Search NORINE for peptide: strict or relaxed

AMP-binding (539..949): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVedIGAVgK
Nearest Stachelhaus code:: arg
Stachelhaus code match:: 70% (weak)

ctg33_586

Search NORINE for peptide: strict or relaxed

AMP-binding (277..712): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiWeMtadDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 50% (weak)

ctg33_589

Search NORINE for peptide: strict or relaxed

AMP-binding (467..872): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGhVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

ctg33_591

Search NORINE for peptide: strict or relaxed

AMP-binding (463..865): asn

NRPSPredictor2: asn

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

ctg33_596

PKS_AT (534..830): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 87.5%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 162.5
inactive: 114.1
Methoxymalonyl-CoA: 63.5
Methylmalonyl-CoA: 54.9
Isobutyryl-CoA: 39.6
Propionyl-CoA: 28.4
Benzoyl-CoA: 26.2
Ethylmalonyl-CoA: 24.7
CHC-CoA: 15.4
2-Methylbutyryl-CoA: 14.6
Acetyl-CoA: 10.9
fatty_acid: 9.8
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0

ctg33_598

Search NORINE for peptide: strict or relaxed

CAL_domain (48..479): pk

minowa: NH2

Prediction, score:

NH2: 32.7
fatty_acid: 17.9
AHBA: 15.1
Acetyl-CoA: -0.1
shikimic_acid: -2.5

AMP-binding (1178..1567): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

c00039_3300026.. - Region 1 - NRPS

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Location: 19,123 - 77,293 nt. (total: 58,171 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 19122 - 77293:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (ile) + (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg39_36

Search NORINE for peptide: strict or relaxed

AMP-binding (495..913): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAFTiAAVwK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 80% (moderate)

ctg39_37

Search NORINE for peptide: strict or relaxed

AMP-binding (492..891): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

ctg39_44

Search NORINE for peptide: strict or relaxed

AMP-binding (547..943): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

c00043_3300026.. - Region 1 - NRPS

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Location: 210,508 - 257,287 nt. (total: 46,780 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 210507 - 257287:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg43_186

Search NORINE for peptide: strict or relaxed

AMP-binding (289..717): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DPRHfsfqaK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 50% (weak)

AMP-binding (1381..1790): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DmEdVGTisK
Nearest Stachelhaus code:: lys-b
Stachelhaus code match:: 60% (weak)

c00043_3300026.. - Region 2 - terpene

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Location: 400,523 - 421,458 nt. (total: 20,936 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

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other genes

resistance

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Gene details

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c00053_3300026.. - Region 1 - T1PKS

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Location: 1 - 24,278 nt. (total: 24,278 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 24278:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg53_2

PKS_AT (530..825): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 95.8%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 224.8
inactive: 178.7
Methoxymalonyl-CoA: 81.8
Methylmalonyl-CoA: 74.5
Propionyl-CoA: 38.5
Ethylmalonyl-CoA: 33.7
2-Methylbutyryl-CoA: 30.4
Isobutyryl-CoA: 27.8
trans-1,2-CPDA: 20.7
CHC-CoA: 17.2
Benzoyl-CoA: 15.4
3-Methylbutyryl-CoA: 14.4
Acetyl-CoA: 13.4
fatty_acid: 11.4

c00053_3300026.. - Region 2 - T1PKS,hglE-KS

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Location: 118,825 - 171,730 nt. (total: 52,906 nt) Show pHMM detection rules used

hglE-KS: (hglE or hglD)
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 118824 - 171730:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg53_120

PKS_AT (626..924): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 70.8%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 94.7
Methoxymalonyl-CoA: 37.2
inactive: 32.9
Methylmalonyl-CoA: 27.5
Isobutyryl-CoA: 16.1
CHC-CoA: 15.9
fatty_acid: 12.6
Benzoyl-CoA: 10.0
trans-1,2-CPDA: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg53_122

PKS_AT (1045..1359): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

c00054_3300026.. - Region 1 - T1PKS,hglE-KS

Download region GenBank file

Location: 32,387 - 84,431 nt. (total: 52,045 nt) Show pHMM detection rules used

hglE-KS: (hglE or hglD)
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 32386 - 84431:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg54_53

PKS_AT (643..941): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 70.8%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 107.4
inactive: 40.6
Methoxymalonyl-CoA: 34.8
Methylmalonyl-CoA: 31.0
CHC-CoA: 21.3
Isobutyryl-CoA: 10.8
fatty_acid: 10.5
trans-1,2-CPDA: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg54_56

PKS_AT (640..933): mxmal

ATSignature: (unknown)

No matches above 50%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 14.4
Isobutyryl-CoA: 13.3
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0