LOCUS       c00006_3300027..       14888 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027111.a:Ga0209281_1000018.
ACCESSION   c00006_3300027..
VERSION     c00006_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 12:02:49
            Original ID  :: 3300027111.a:Ga0209281_1000018
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 433427
            Orig. end    :: 448315
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14888
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[438427:443315]"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9888
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
     cand_cluster    1..14888
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /kind="single"
                     /product="NAGGN"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14888
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAGGN"
                     /region_number="2"
                     /rules="((TIGR03104 or cds(GATase_7 and Asn_synthase)) and
                     TIGR03103 and (TIGR03106 or Peptidase_M42))"
                     /tool="antismash"
     CDS             1584..3566
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103:FAD dependent oxidoreductase (Score: 114;
                     E-value: 1.6e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_406"
                     /transl_table=11
                     /translation="MTPIQQHAQLDWDEQGRPRSRVFDDVYFSDQSGLDETRYVFLEQN
                     QLAERFAALPEDGRLVIGETGFGTGLNFLCAWQLFEQCAPAGARLHFVSVEKYPLSPED
                     LRRALALWPQLQAQAQQLLDQYVAIHQGFQRLVLANGRVTLTLLIGDALEQLPQLDARI
                     DAWFLDGFAPARNPEMWTAELFAELARLAAPGSTLSTFTSTGWVRRLLNAAGFKMKRTP
                     GIGHKWEILRGVFLGRPEQTPAPSAAKPWYARPAALGNERRALVIGGGLAGCASAASLA
                     ARGWQVTLLERHAGLAEEASGNPQGVLYLKLSAHGTALSQMILSGFGYTRRLLEHLQRG
                     VDWDGCGVLQLAFNHKEAERQAQLAEAFPADLLHPLAQPEAQRLSGIGLACGGLFYPEA
                     GWVHPPALCRWQASGTAIEVQAHHDVLQLRRVDGQWQAWDGQRCLASAPVVILASAAEI
                     KRFEPAAGLPLKRIRGQITRLPQTARSQDLATVVCAEGYVAPPRLGEHTLGASFDFNSD
                     DLTPTAAEHAGNLQMLEEISEDLLERLGAATLDPQRLEGRAAFRCTSPDYLPIVGPLAD
                     SQAFHEAYHALSKDARQVPDIPCPWLDGLYVNSGHGSRGLITAPLSGELIAAWLDDEPL
                     PLPRSVAEACHPNRFALRALIRGKA"
     CDS             3853..4722
                     /locus_tag="ctg6_407"
                     /transl_table=11
                     /translation="MGMNKIIRLIALAAIITSAACSKQDNFNTLSPGEMLKPISLQAHN
                     NPTWASSDSQYEKSQNPAKWSPYFWASNAAALQSIANDKPRLEATVKALMDEMKANSIV
                     DSDGNYRVIYRFPYVFDKYPMSAPWYSAFGNAAIAVGLMHIRNSTGDTSNDGLINEYLD
                     TIVKKYSYKTPEGNIWFAEYISDDLPDGHVSVINGHFFVVAAMYEWKSMSKTNRYDRPI
                     SQGLDTMRDELAKFIQEGYFSYADGFKHMKDYGQQRAVNFAVASCKLRDEICPIAVRYQ
                     KLFNEWSK"
     CDS             5001..6773
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03104"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     GATase_7"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 598.7; E-value: 2e-181)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_408"
                     /sec_met_domain="Asn_synthase (E-value: 1.5e-84, bitscore:
                     279.7, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 4e-44, bitscore: 144.5,
                     seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03104 (E-value: 1.3e-296, bitscore:
                     979.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGELRFDQQPADLAAVERITHHLAPRGPDAWGFHSQGPIAL
                     GHRRLKIMDLSDGSAQPMIDNQLGLSLAFNGAIYNFPELRAELEALGYAFHSGGDTEVL
                     LKGYHAWGEALLPKLNGMFAFAIWERDAKRLFIARDRLGVKPLYLSRTGQRLRFASALP
                     ALLKGGDISPMLDPVALNHYLNFHAVVPAPRTLLAGVEKLPPATWMRVEADGTTEQKTW
                     WTLPYGPRADEQNLNLEDWIDRVLDSTREAVAIRQRAAVDVGVLLSGGVDSSLLVGLLR
                     EVGVEDLSTFSIGFQDAGGERGDEFQYSDLIAKHYGTRHHQLRIDEKEIIEQLPAAFRA
                     MSEPMVSHDCIAFYLLSREVAKHCKVVQSGQGADELFAGYHWYPQVDDASDPYAAYRAA
                     FFDRSYEEYADTVQPKWLTANDAAGDFVKEHFAQPGADAAVDKALRLDSTVMLVDDPVK
                     RVDNMTMAWGLEARTPFLDYRLVELSARVPAKFKLPDGGKQVLKEAARRVIPSEVIDRK
                     KGYFPVPGLKHLEGDTLAWVRELLLDPSQDRGLFNPAMLDRLLTDPNGQLTPLRGSRLW
                     QLAALNLWLSEQGI"
     CDS             6777..8522
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03103"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_409"
                     /sec_met_domain="RimK (E-value: 3.3e-10, bitscore: 34.9,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03103 (E-value: 3.4e-270, bitscore:
                     892.1, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPHPTVHNQRLLRGQAPSYERLQARLAEDGSAMGADPIAVHCGW
                     GRLLIGHTFPDPACLAQELLNEQPGERDIALYVAAPQQVLGLEPAHLFLDPSDTLRLWF
                     SDYRQATRVFRGFRIRRAQGDADWQAINQLYQARGMLPIDPQRLTPRHEGGPVYWLAED
                     DDTGAVIGSVMGLNHQKAFNDPENGSSLWCLAVDPQCSRPGVGEVLVRHLIEHFMSRGL
                     SYLDLSVLHDNRLAKNLYAKLGFRNLSTFAIKRKNGINLPLFLGPGPEAQFNPYARIIV
                     EEAHRRGIEVQVDDAEAGLFTLVHGSRRVRCRESLSDLTSAISMTLCQDKSLTHKVLKN
                     AGLNLPAQQLAGNADDNLAFLDEHERVVVKPLDGEQGQGVAVDLRTIEEVQAAIEAARQ
                     FDSRVLLESFHEGLDLRILVIGFEVVAAAIRRPAEVIGDGRHTIGALIEAQSRRRQAAT
                     GGESKIPMDAETERTLKAAGFDYDSVLPAGEHLFVRRTANLHTGGVLEDVTGILHPTLA
                     DAAVRAARALDIPMVGLDLLVPAADQPDYVFIEANERAGLANHEPQPTAERFVDLLFPH
                     SQAVA"
     CDS             8698..9888
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Peptidase_M42"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03106"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_410"
                     /sec_met_domain="TIGR03106 (E-value: 4.6e-178, bitscore:
                     586.2, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M42 (E-value: 1.5e-74, bitscore:
                     245.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKIPEPNLEYLQKVLLEMLAIPSPTGFTDTIVRYVAERLEELG
                     IPFEMTRRGTIRATLKGRKNSPDRAVSAHLDTIGASVRAIKDNGRLTLAPVGCWSSRFA
                     EGSRVSLFTDTGVIRGSVLPLMASGHAFNTAVDEMPISWDHIELRLDAYCTTRADCETL
                     GVSVGDYVAFDPLPEFTESGHISARHLDDKAGVAALLAALKAIVDSGEELLIDCHPLFT
                     ITEETGSGAAAALPWDVSEFVGIDIAPVAPGQQSSEHAVSVAMQDSGGPYDYHLSRHLL
                     KLAKENELPARRDLFRYYFSDAHSAITAGHDIRTALLAFGCDATHGYERTHIDSLAALS
                     RLLGAYILSPPVFASDAQPAQGSLDRFSHQIEHDAQMESDTRVPSVDSLLGQRSDS"
     CDS             10064..10291
                     /locus_tag="ctg6_411"
                     /transl_table=11
                     /translation="MLIPHDQLEVDTLTRLIEDFVTRDGTDNGDDTPLETRVLRVRQAL
                     TKGQAMIVFDPESEQCQLMLKHDVPKHLFD"
     CDS             complement(10280..10480)
                     /locus_tag="ctg6_412"
                     /transl_table=11
                     /translation="MLVLSRAVGELISIGDDISVRVLSVTGGTVRFGVEAPRHIDVHRS
                     EIYEKIQKKKAHAQRKACSVE"
     CDS             complement(10630..10962)
                     /locus_tag="ctg6_413"
                     /transl_table=11
                     /translation="MLNYLWFFLAALFEIAGCYAFWMWLRQGKSAWWIAPALISLTLFA
                     LLLTRIEATYAGRAYAAYGGIYIIASIGWLAVVERVRPLGSDWIGVALCVLGASVILFG
                     PRFSAT"
     CDS             complement(11020..11835)
                     /NRPS_PKS="Domain: PKS_KR (4-163). E-value: 9.2e-11. Score:
                     33.7. Matches aSDomain: nrpspksdomains_ctg6_414_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     194.5; E-value: 3.5e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_414"
                     /sec_met_domain="adh_short (E-value: 2.1e-34, bitscore:
                     114.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNRMMITGAGSGLGREIALRWAREGWRLALSDVSEPGLVETLRL
                     VREAGGDGFIQRCDVRDYSQLTAFAQACEEKFGGIDIIVNNAGVASGGFFSELSLEDWD
                     WQIAINLMGVVKGCKAFLPLLEQSRGKIINIASMAALMQGPAMSNYNVAKAGVVALSES
                     LLVELAQQEIGVHVVCPSFFQTNLLDSFRGPTPAMKAQVGKLLESSPISAADIADYIYQ
                     HVAQGQFMILPHEQGRAAWALKQQAPQKLYDEMTVMADKMRAKARQNPS"
     aSDomain        complement(11347..11823)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_414_PKS_KR.1"
                     /evalue="9.20E-11"
                     /label="ctg6_414_PKS_KR.1"
                     /locus_tag="ctg6_414"
                     /protein_end="163"
                     /protein_start="4"
                     /score="33.7"
                     /specificity="KR stereochemistry: C2"
                     /specificity="KR activity: inactive"
                     /tool="antismash"
                     /translation="MMITGAGSGLGREIALRWAREGWRLALSDVSEPGLVETLRLVREA
                     GGDGFIQRCDVRDYSQLTAFAQACEEKFGGIDIIVNNAGVASGGFFSELSLEDWDWQIA
                     INLMGVVKGCKAFLPLLEQSRGKIINIASMAALMQGPAMSNYNVAKAGVVALSESL"
     aSModule        11347..11823
                     /domains="nrpspksdomains_ctg6_414_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg6_414"
                     /tool="antismash"
                     /type="unknown"
     CDS             12111..12263
                     /locus_tag="ctg6_415"
                     /transl_table=11
                     /translation="MGTILIIILILLLIGGLPVFPHSRSWGYGPSGIIGVVLVVLLVLL
                     LLGKI"
     CDS             complement(12322..14415)
                     /locus_tag="ctg6_416"
                     /transl_table=11
                     /translation="MAIPDALSQQRTTHRLLQPTVKSHLAYTLLCALVMMVMFSLLRVA
                     LLVYNREMILDTPASTFVEAFVNGLRFDLRLVVYLCIPLLLALFSARAMAARGFFRFWL
                     TVTSSIALFLGLMEMDFYREFHQRLNGLVFQYVKEDPKTVMSMLWYGFPVVRYLLAWVG
                     GTIILSLAFKGADRATRPRGPFSGGSIGTRQIAPWYGRVAVFMVCLLVAVVAARGTLRQ
                     GPPLRWGDVYTTDSNFANQLGLNGTLSLVAAAKSRMSEDRDNIWKATLEQPLAQQTVRD
                     MLVMPDDKLVDTETAAVRRDYTPPADKTLPIKNVVVILMESMAGHSVGALGASGNITPY
                     LDKLSKEGLLFDRFFSNGTHTHQGMFATMACFPNLPGFEYLMQTPEGSHKLSGLPQLLS
                     ARDYDDVYVYNGDFAWDNQSGFFSSQGMTNFIGRNDFVNPVFSDPTWGVSDQDMFDRGL
                     IELKARENGKPFYALLQTLSNHTPYALPTPLPVERVTDRGSLNEHLTAMRYADWALGQF
                     FEKARKEPYFKETLFVVVGDHGFGNERQITEMDLGRFNVPLLLIGPGVQEKFGQRSHTV
                     GTQVDIVPTIMGRIGGQVRNQCWGRDLLNLPQGDTGFGVIKPSGSEQTTAIIKDDQILV
                     LPKEKEMPPKMYRYELGANPRAEIVPDAPDTAAMKLKLESFLQTATKSLLDNTAGVIDG
                     KPD"
ORIGIN
        1 gtcgttggcc tccaccagtg tccaggggga aatctcggtg ctggtgcggt ccaccatgtc
       61 acacaccgcg gaccggtagg cgtcccactt gtcgcggttg cgccaatcgt cctcggtgat
      121 cttgaagcgc ttgaacggga tctcctcacg cgcctggaag cgttcaagct gggtttcctt
      181 gtcgatggcc agccagaact tgaccaccac cacgccggcg tcggcgatct gttcctcgaa
      241 atcgttgatc tcgccgtagg ccctcaacca atcggcccgg ctgcaaaagc cctcgacccg
      301 ttccaccagc acccggccat accaggaacg gtcgaacacg gtgaacttgc cccgtgccgg
      361 cagatgccgc cagaaccgcc acatataggg atgggcgcgc tcctcctcgg tgggagcggc
      421 gatcggcacg atgctgtatt ggcgcggatc gagggccgcc gcgacccgac ggatcgcgcc
      481 gcccttgccc gccgcatcgt tgccttcgaa caccgccacc agcgcatgcc ggcgcatgcg
      541 tttgtcccgc agcaggccgg cgaaacgcgc ctgctcggta atcagctgtt cttcgtagtc
      601 gtccttttcc aggcgcaggg tcatgtccag gctgtcgatc agcgtgacct ggtcgtccag
      661 tgccggcagc ggcgccacgg cgactttttc cggcttgacc ttcggccggt ccaacgcctg
      721 gcgcaagcct tcgagcagaa tccgccccac cgtcaggctg cgataacagc tgtccacgcc
      781 ctcgatcacg tgccaaggcg cgtagtcgcg actggtacga cgcaagaccc gctcgccgta
      841 tttgacgaac ttgtcgtagg tctgcgattg ctgccagtcc agcgggctga tgcgccaact
      901 gtgcagcggg tcatccttaa gccccttgag ccgggctttc atctgtttct tggacaggtg
      961 aaaccagaat ttgaagatca acgcgccttc gtcgcaaagc attttttcca ggcgctcggc
     1021 ggcgttgatc gcctggtcga gccgcggatc cttgaactcg ccatggaccc gcccctgcaa
     1081 catctggctg taccagttgc caaagaagat ccccatgcgc cccttggccg gcagcatccg
     1141 ccagtagcgc caggccggag gatgcgccag ttcctcgtcg gtctgctggt cgaaggtgcg
     1201 cacttcgatc agccgcgggt ccatccactc attgagcaat ttcaccgtct cacccttgcc
     1261 cgcgccttcg atgccgttga tcagcacgat gaccggaaaa cggccctgct gctgcaactc
     1321 gaattgcgct tcgagcagcg cttcacgcag ggccggcacc tcggcctcga aggtgtcttt
     1381 gtcgatgacg tgaccgattt cagcggattc aaacatgggc aactccttcc aaggatcagc
     1441 caagactagc ggattggatg ccctgcggtg tagcaccagg aaggatcatt ccctacgcct
     1501 ggcatgacaa tgcctgtgcg cacgctgcgc gttcggcttt gtggatcagc tagaatggcc
     1561 tccccgtttt caccgagcct gccatgacgc ccatccagca acacgcccaa ctcgactggg
     1621 atgaacaggg tcgcccgcgt tcgcgggtgt tcgacgacgt gtatttttcc gatcagtcgg
     1681 ggctggatga aacccgctac gtgttccttg aacagaacca gctggccgag cgcttcgccg
     1741 cgctgcccga ggacgggcgc ctggtgatcg gcgaaaccgg gttcggcacc ggcctgaact
     1801 tcctctgcgc ctggcaactg ttcgagcagt gcgcaccggc gggggcgcgg ctgcatttcg
     1861 tcagcgtcga gaagtacccc ttgagccccg aggacctgcg tcgcgccctg gccctctggc
     1921 cgcagcttca agcccaggcg cagcagttac tggaccaata cgtggccatc caccagggtt
     1981 tccaacgcct ggtcctggcc aatggccggg tgacgctgac cttgctgatc ggcgacgcgc
     2041 tggagcagtt gccgcaactg gatgcccgca tcgacgcgtg gttcctcgac gggtttgcac
     2101 ccgccaggaa ccccgagatg tggacggccg agctgttcgc cgaactggcg cggctggcgg
     2161 ccccgggatc gaccctcagc accttcacca gcaccggttg ggttcggcgg ttgctgaacg
     2221 cggcaggttt caagatgaaa cgcacgcccg gcatcggcca taaatgggag atcctgcgcg
     2281 gcgtgttcct gggccggccg gaacagacac cggcgccgtc cgcggcaaaa ccctggtacg
     2341 cccgccccgc ggccctcggc aacgagcgtc gggcattggt gatcggtggc ggcctggccg
     2401 gttgcgccag cgccgccagc ctcgccgcgc ggggctggca ggtgacgctg ctggaacgac
     2461 acgccgggtt ggccgaagag gcgtcgggca atccgcaggg cgtgctgtac ctcaagctgt
     2521 cggcccacgg caccgcgctg tcgcagatga tcctcagcgg cttcggctac acccgccgtc
     2581 tgttggagca cctgcaacgg ggcgtcgact gggacggctg cggcgtcctg caactggcct
     2641 tcaatcacaa ggaagccgag cgccaggcgc aactggccga ggcgttcccc gctgacttgc
     2701 tgcaccccct ggcgcagccc gaggcacaaa ggctgtcagg tatcggcctg gcctgcggtg
     2761 gtctgttcta tcccgaagcc ggctgggtgc atccgccggc gctgtgccgc tggcaggcct
     2821 cgggcaccgc gatcgaggtg caagcgcacc atgacgtgct gcaattgcgt cgcgtcgatg
     2881 gccagtggca agcgtgggac ggtcaacgct gcctggccag cgcgccggtg gtgatcctcg
     2941 ccagtgccgc cgaaatcaag cgtttcgaac cggccgccgg attgcccctc aagcgcattc
     3001 gcgggcaaat cacccggctg ccgcaaaccg cgcgcagcca ggacctggcg accgtggtct
     3061 gcgccgaagg ctacgtggcg ccgccacgtc tgggcgagca caccctgggc gccagcttcg
     3121 acttcaacag cgacgacctg acccccaccg ctgccgaaca cgccggcaac ctgcagatgc
     3181 tcgaagaaat ttccgaggac ctgctcgaac gcctcggcgc cgccaccctg gacccgcaac
     3241 ggctcgaagg ccgcgcggcg ttccgctgca ccagcccgga ctacctgccg atcgtagggc
     3301 ccctagctga cagccaggcc ttccacgagg cttaccacgc cttgagcaaa gacgcccggc
     3361 aagtgccgga catcccctgc ccctggctcg acggcctcta cgtcaacagc ggccacggct
     3421 cgcgcggcct gatcaccgcg cccctgtcgg gcgaactgat cgccgcctgg ctcgacgacg
     3481 aacccctgcc gctgccccga agcgtggccg aagcctgcca cccgaaccgg ttcgcgttgc
     3541 gagcgttgat tcgaggcaag gcctgaacca cataagaatc cctatggaag ccgttggcga
     3601 ctctcgaacg gaacgatgaa ttcgtgaaaa ctgcactggc cgtgataagc accccagaat
     3661 aagccctatt ctgccgtcga tgcagattca gtcggagcta tccaatatgc atctctaacc
     3721 tcatctaaag cctgccatgg ttcagggccg aacctcgcat ttggacagcc gccagccccg
     3781 tagctggcca tgacgcattg tgtaaaatcc tgcacgaaca gtagagttcg cgccactgaa
     3841 tggagttagg gcatgggcat gaataaaata ataaggctta tcgcactggc tgcgattatc
     3901 acaagcgctg catgcagcaa gcaggataac ttcaacactt tgtcgccagg cgagatgctc
     3961 aagcccattt ccttgcaagc tcacaacaac cctacgtggg caagttctga ctcccagtac
     4021 gagaaatcgc agaaccctgc caaatggtcg ccttatttct gggcatcgaa tgcagcggcg
     4081 cttcagagca tcgccaatga caagcctcgc cttgaggcga cggtcaaggc tctgatggat
     4141 gagatgaagg caaactcgat tgttgatagc gatggtaact accgagtcat ctaccggttc
     4201 ccatacgtct tcgacaagta cccgatgtcg gcgccttggt actcggcttt cgggaacgcg
     4261 gctatcgctg taggcctgat gcacatcagg aactcgacag gggacacatc gaacgatggg
     4321 ttgattaatg aatacctgga caccatcgtc aagaagtatt catacaagac ccctgaagga
     4381 aacatatggt ttgctgaata catctctgat gacctccctg atggccatgt gagcgtgatc
     4441 aacggtcact tcttcgtggt cgccgccatg tatgaatgga agagcatgag taaaacaaat
     4501 cggtacgaca ggccaatatc ccaaggattg gataccatgc gcgacgagtt ggcaaagttc
     4561 attcaggaag gatacttctc atacgctgat ggtttcaaac acatgaagga ttatggtcag
     4621 cagcgtgcag taaacttcgc tgttgcttcc tgcaaactcc gcgacgaaat atgccccatc
     4681 gctgttcggt atcagaagct cttcaatgaa tggtcgaagt gatggtcctg tcgttggcgg
     4741 ttaccccata gcaggcccat ccgccattcc tgcactgccg gtcgcacctg cgtcggcgac
     4801 catcagtgca ggggcagtac cattagcccc gccagcttct gcatcggcgt catgcgagag
     4861 cccgccggag ccgtcccgtc cgtcggctta taacgcatcg atctaaaact cacagcaatc
     4921 ccaccggtca gtttcagagt acccgccctt tcggcggacg ttgcttgacc cctccccaac
     4981 ggaaaaaccg gtaaggactt atgtgcggat tagctggaga gttacgtttc gatcaacaac
     5041 ctgcggacct tgcggccgta gagcgaatca cccatcacct ggccccgcgt ggccctgacg
     5101 catggggttt ccatagccag gggccgattg ccctgggcca ccgtcgcctg aagatcatgg
     5161 acctgtcgga cggctcggcg cagccgatga tcgacaatca gttgggcctg tccctggcct
     5221 tcaacggcgc catctacaac ttcccggaac tgcgcgccga gcttgaagca ctgggctacg
     5281 ccttccattc cggcggcgac accgaagtgc tgctcaaggg ctatcacgcc tggggcgagg
     5341 ccctgctgcc caagctcaac ggcatgtttg ccttcgccat ctgggaacgg gacgccaagc
     5401 ggctgttcat cgcccgcgac cgcctcggcg tcaagccgct gtacctgtcg cgcactggcc
     5461 agcgcttgcg ctttgcctcg gccctgccgg ccctgctcaa gggcggtgac atcagcccga
     5521 tgctcgaccc ggtggccctg aaccactacc tgaatttcca tgcggtggtc ccggcgcctc
     5581 gcaccctgtt ggccggcgtc gaaaaactac cgccagccac ctggatgcgg gtcgaagccg
     5641 acggcaccac cgagcagaaa acctggtgga ccctgcccta cggcccccgc gccgatgaac
     5701 agaacctgaa tctggaagac tggatcgacc gcgtgctcga cagcacccgc gaagccgtcg
     5761 ccattcgcca acgcgcggcc gtcgatgtgg gcgtgctgtt gtccggcggc gtcgactcga
     5821 gcctgttggt ggggttactg cgcgaagtcg gcgtggaaga cttgtccacc ttttccatcg
     5881 gtttccagga tgccggcggc gagcgcggcg acgaattcca gtattcggac ctgatcgcca
     5941 agcactatgg cacccgccac catcaactgc gcatcgacga aaaagagatc atcgaacaac
     6001 tgccggcggc cttccgcgcc atgagcgaac cgatggtcag ccacgactgc atcgcctttt
     6061 acctgctgtc gcgagaagtg gccaagcatt gcaaggtggt gcaaagcggc cagggtgccg
     6121 atgagctgtt cgccggttat cactggtacc cgcaagtgga cgacgccagc gacccttacg
     6181 cggcctaccg tgccgcattc ttcgaccgta gctacgagga atacgccgac accgtgcagc
     6241 ccaagtggct gacggccaat gacgccgccg gtgacttcgt caaggaacat ttcgcccaac
     6301 ccggcgccga cgccgcggtc gacaaggcgc tgcgcctgga cagcacggtg atgctggtgg
     6361 acgacccggt caagcgcgtc gacaacatga ccatggcctg gggcctggaa gcgcgcacgc
     6421 cgttcctcga ctaccggttg gtggagcttt cggcccgggt gccggcgaag ttcaagctgc
     6481 ccgacggcgg caagcaggtg ctcaaggaag ccgcccggcg cgtgatcccc agcgaggtaa
     6541 tcgaccgcaa gaagggctat ttccccgtgc ctgggctcaa gcacctggaa ggcgacacgc
     6601 tggcctgggt gcgcgaactg ctgctggatc cgagccagga tcgcggcctg ttcaacccgg
     6661 ccatgctcga ccgcctgctc accgacccca acggccaatt gaccccgctg cgcggttcgc
     6721 gcctgtggca actggcggcg ctgaacctgt ggctcagcga gcaaggaatc tgattgatga
     6781 aaccccaccc taccgttcac aaccaacgcc tcttgcgggg ccaggcgcct tcgtacgaac
     6841 gtctgcaggc gcgcctggcc gaagatggca gcgcaatggg cgctgacccg atcgccgtcc
     6901 actgcggctg gggtcggctg ctgatcggcc acacgttccc cgacccggct tgcctggccc
     6961 aggaactgct caatgagcaa ccgggcgaac gcgacattgc cctgtacgtc gccgcgcccc
     7021 agcaagtcct ggggctggaa ccggcgcatc tgttcctcga cccgtccgac accttgcgcc
     7081 tgtggttcag cgattatcgc caggccacgc gggtgttccg tgggtttcgc atccgccggg
     7141 cgcaagggga cgccgactgg caagccatca accagcttta ccaggcccgc ggcatgttgc
     7201 ccatcgaccc gcaacgcctg accccgcgtc acgaaggcgg cccggtctac tggctggccg
     7261 aagacgacga taccggcgcg gtgatcggca gcgtcatggg cctgaatcac cagaaagcct
     7321 tcaacgaccc ggaaaacggc agcagcctct ggtgcctcgc cgtggacccg caatgctcac
     7381 ggccaggtgt tggcgaagtg ctggtgcgcc atctcatcga gcatttcatg agccggggcc
     7441 tgagctacct cgacctgtcg gtgctgcacg acaatcgctt ggcgaaaaac ctctacgcca
     7501 agctcggttt ccgcaacctc tcgacctttg ccatcaaacg caagaacggc atcaacctgc
     7561 cgctgttcct tggcccgggt cccgaggctc agttcaaccc ttatgcgcgg atcattgtcg
     7621 aggaagccca ccgtcgcggc atcgaggtcc aggtggacga cgccgaggcc gggttgttca
     7681 ccctggtcca cggcagccgc cgggtgcgtt gccgcgaatc cctgagtgac ctgaccagcg
     7741 ccatcagcat gaccctgtgc caggacaaga gcctgaccca caaggtgctg aagaacgccg
     7801 gcctgaacct gccggcgcaa caactggcgg gcaatgccga cgacaacctg gcgtttctcg
     7861 acgagcacga acgggtcgtg gtcaagccgc tggacggtga acaaggccag ggcgtggcag
     7921 tggacctgcg caccattgaa gaagtacaag ccgccatcga agcggctcgg cagttcgaca
     7981 gccgggtgct gctggaaagc ttccacgagg ggttggacct gcggatcctg gtgatcggtt
     8041 tcgaagtggt ggcggccgcc atccggcggc cggcggaagt gatcggcgac ggccgtcaca
     8101 ccatcggcgc cctgatcgaa gcccagagtc gccgacgcca ggccgccaca ggtggcgaaa
     8161 gcaagatccc gatggatgcc gagaccgagc gcacgctcaa ggcggcgggg ttcgactacg
     8221 acagcgtcct gccggccgga gagcatctgt tcgtgcggcg cacggccaac cttcataccg
     8281 gcggggtact ggaagacgtc accggcatcc tccatccgac cctggccgat gcggcggtac
     8341 gcgccgcccg agcgttggac attcccatgg tcggccttga cctgctggtg ccggcggccg
     8401 accagcccga ctatgtgttc atcgaagcca acgaacgcgc cggcctggcc aaccatgaac
     8461 cgcaacccac tgctgaacgc tttgtggacc tgctgtttcc ccatagccag gcggtggcct
     8521 gagcaccgtt cccagtggcg agggagcttg ctcccgctgg gtcgcggagc gccccccttc
     8581 gatgcgaatg tccggattat tcagggctgg agctgcgacc gctttgcgtt cgaacgggag
     8641 caagctccct cgccacaagg ctcttctgcc taaccttatc gtccgagagg agtttccatg
     8701 atcagcaaaa ttcccgaacc gaatctcgaa tacctgcaaa aagtcttgct ggaaatgctc
     8761 gccattccca gcccgaccgg cttcaccgac accatcgtgc gctatgtcgc cgaacggctc
     8821 gaagagttgg gtatcccctt tgaaatgacc cgtcgcggca ccattcgcgc caccctcaag
     8881 ggccgcaaga acagccccga ccgcgcggtg tccgcgcacc tggacaccat cggcgcctcg
     8941 gtacgggcca tcaaggacaa tggacgcctg accttggccc cggtgggctg ctggtcgagc
     9001 cggtttgccg agggcagccg ggtcagcctg tttaccgaca ccggcgtgat tcgcggcagc
     9061 gtgctgccct tgatggcatc cgggcatgcg ttcaacaccg ccgtggatga aatgcccatc
     9121 agctgggacc acatcgaact gcgcctggac gcctactgca ccacccgcgc cgattgcgaa
     9181 accctgggcg tgagcgttgg cgactacgtg gccttcgacc cgttgccgga gttcaccgaa
     9241 agcggtcaca tcagcgcccg ccacctggat gacaaggccg gcgtcgccgc gctgctggcg
     9301 gcactcaagg ccattgtcga cagcggtgaa gaactgctga tcgactgcca cccgctgttc
     9361 accatcaccg aggaaaccgg cagcggtgca gccgccgcgc tgccctggga cgtcagcgaa
     9421 ttcgtcggca tcgatatcgc gccggtcgcg cccggccagc agtcgagcga acatgcggtg
     9481 agcgtggcca tgcaggactc cggtggcccc tacgactacc acctgtcgcg acacctgctg
     9541 aaactggcca aggagaacga gctgccggcc cgccgggatc tgttccgcta ttatttcagc
     9601 gacgcccact cggccatcac cgccggccac gacattcgca ccgccctgct ggccttcggc
     9661 tgcgacgcca cccatggcta cgaacgcacc cacatcgaca gcctggccgc cctcagccgc
     9721 ttgctcggcg cctacatcct cagcccaccc gtgtttgcca gcgacgcgca accggcccaa
     9781 ggctcgctgg accgcttcag tcaccagatc gaacacgatg cgcagatgga aagcgatacc
     9841 cgggtgcctt cggtggatag cctgctgggg caacggtcgg acagctgagg cgcccgcctt
     9901 gaagggcggc gtcagcaaaa ccgatttcgc gagcaagctc gctcccacaa aggttgcatg
     9961 ccaatgtgag agcgagcttg ctcgcgaagc cgacaacgca ccccggctag ccgcaaacgc
    10021 ccgttggccg tagcatcgcc tcattgtcta gccgaggtac cccatgctga ttccccacga
    10081 ccaactcgaa gtcgacacac tcacccgcct gatcgaggat ttcgtgaccc gcgacggcac
    10141 cgacaatggc gacgacacgc ccctcgaaac tcgcgtactg cgcgttcgac aagcgctgac
    10201 caagggccag gcgatgatcg tgttcgatcc cgagagcgaa cagtgccaac tgatgctcaa
    10261 gcacgacgtg cccaagcacc tattcgactg aacaggcctt gcgctgggcg tgggcttttt
    10321 tcttctggat cttttcgtag atttcggagc gatggacatc gatgtgtcgg ggcgcttcga
    10381 cgccaaaacg cacggtgccg ccggtgaccg acagcacgcg aacggaaatg tcgtcaccga
    10441 tggaaatcag ttcgcccaca gcgcggctta gtacgagcat ggttcttgtc cttaagaatg
    10501 tctggacctc gaccatgccc ggcctgattc agcttctcaa ggctcccacg acaaatcagt
    10561 aaggccctac aagcaaagca cttcgggctg acggaaacgt cctgcaaaac ctgtatagcg
    10621 gcgtttattt caggtcgccg agaagcgtgg cccgaacagg atcacgctcg cccccagcac
    10681 gcacagcgcc acgccgatcc agtccgaacc cagcggccgc acccgctcca ccacggccag
    10741 ccagccaatc gaggcgatga tgtagatacc gccataggcg gcgtaggcgc gaccggcata
    10801 agtggcttcg atgcgggtca gcaacagggc aaagagggtc aggctgatca gcgccggggc
    10861 gatccaccag gcgctcttgc cctggcgcag ccacatccag aacgcgtagc aaccggcgat
    10921 ttcaaacagc gcggcaagaa agaaccacag gtaattgagc atgcaaatgt ccatcaggaa
    10981 ggccgaatcg cgccatcctg aggacaccgg gccgccaggt caactcgggt tctgtcgagc
    11041 cttggcgcgc atcttgtcgg ccatgacggt catttcgtcg tagagcttct gcggggcctg
    11101 ctgcttgagc gcccacgccg cccgcccctg ctcgtggggc aggatcatga actggccctg
    11161 ggcgacgtgc tggtagatgt aatcggcgat gtcggcggcg ctgatgggcg agctttccag
    11221 cagtttgcca acctgggcct tcatggccgg tgtcggccca cggaaggagt cgagcaggtt
    11281 ggtctggaag aacgacgggc acaccacgtg cacgccgatt tcctgctggg ccagttcaac
    11341 cagcaggctt tccgacaagg ccaccacgcc ggccttggcc acgttgtagt tgctcatggc
    11401 cggcccttgc atcagcgcgg ccatggaggc gatgttgatg attttgccgc ggctctgctc
    11461 cagcaacggc aagaacgcct tgcagccctt gaccacgccc atcaggttga ttgcgatctg
    11521 ccagtcccag tcttccaggg acagttcgct gaagaacccg cccgaggcca cgcccgcgtt
    11581 attgacgatg atgtcgatgc cgccgaactt ctcttcgcag gcctgggcga aggccgtcag
    11641 ttggctgtag tcgcgcacat cgcaacgttg gatgaaaccg tcgccacctg cctcgcgcac
    11701 caacctcagg gtttccacca ggccgggctc actgacatcc gacaaggcca ggcgccagcc
    11761 ttcgcgggcc cagcgcaacg cgatttcgcg gcccaggccg gagccggccc cagtgatcat
    11821 catgcgattt tgcatagcag acagccttgt tgttccggga gagataggcc gagtgtagcg
    11881 aaggacccgg ccgtccccac gctccatcag attgctgaat ggcgagggca aaccatggcg
    11941 ggatgtgaag ggccccgtgg cggcttgcac actttgtagc gggtactaaa aaacattgaa
    12001 ttttttacag gacgttacgg tcggacctat taagccgccc ggatttaatg catgcgcgct
    12061 ggcagtcaaa agttgcatca acccagaact gaccaataag gaaatctaca atgggcacaa
    12121 ttcttatcat tatcctgatc ctcctgctga tcggtggtct gccggtcttc ccgcactcca
    12181 gaagttgggg ttacggcccg tccggtatta tcggtgtggt gttggtggtg ctgttggtcc
    12241 tgctactact gggcaagata tgaaccacta agaacaaaaa aagaggccct tacgggcctc
    12301 tttttttatg ctcgccgata atcagtccgg cttgccgtcg ataacaccgg cggtgttatc
    12361 caacaagctc ttggtggccg tctgcaggaa cgactcgagc ttgagtttca tcgctgcggt
    12421 gtccggtgca tccgggacga tctccgcacg ggggttggca cccagttcat agcgatacat
    12481 ctttggcggc atttcctttt ccttcggcag caccaggatc tggtcgtcct tgatgatcgc
    12541 cgtggtctgt tcgctgcccg atggcttgat cacgccaaaa ccggtatcgc cctgcggcag
    12601 gttcaaaagg tcacgccccc agcactggtt gcgcacctga ccgccgatcc ggcccatgat
    12661 ggtcggcacg atatcgacct gggtacccac ggtgtggctg cgctggccga acttctcctg
    12721 gacgcccggg ccgatcagca gcaacggcac gttgaagcgg cccaggtcca tttcggtgat
    12781 ctggcgttcg ttgccgaagc catggtcgcc caccaccaca aacagggttt ccttgaagta
    12841 cggttccttg cgggccttct cgaagaactg gcccagggcc cagtcggcgt agcgcatggc
    12901 ggtcaggtgt tcattcaggc tgccacggtc ggtcacccgc tccactggca acggtgtcgg
    12961 cagcgcatac ggcgtgtggt tcgacagggt ctgcagcaag gcgtagaacg gcttgccatt
    13021 ttcccgcgcc ttgagctcga tcaggccacg gtcgaacatg tcctggtcgg acacgcccca
    13081 ggtcggatcg gagaacaccg ggttgacgaa atcgttacgc ccgatgaagt tggtcatgcc
    13141 ctggctgctg aagaaccccg actggttgtc ccaggcaaag tcgccgttgt agacgtacac
    13201 gtcgtcgtag tcacgggcac tgagcaattg cggcagtccc gacagcttgt ggctgccttc
    13261 cggcgtctgc atcaggtatt cgaaaccggg caggttcggg aagcacgcca tggtggcgaa
    13321 catgccctgg tgggtgtggg tgccgttgga gaagaagcgg tcgaacagca ggccttcctt
    13381 ggacagcttg tccaggtaag gcgtgatgtt gcccgatgcg cccagggcgc ccaccgagtg
    13441 accggccatg ctttccatga ggatcaccac cacattcttg atgggcagcg tcttgtcggc
    13501 cggcggcgtg tagtcgcggc gcacggcggc ggtctcggtg tccaccagct tgtcgtcggg
    13561 catgaccagc atgtcgcgca cggtctgctg ggccaacggt tgttcgaggg tggctttcca
    13621 gatgttgtca cggtcttcgg acatccggct cttggccgcc gccaccagcg acagcgtgcc
    13681 gttgaggccc agctggttgg cgaagttcga gtcggtggtg tacacgtcgc cccaacgcag
    13741 cggcgggccc tggcgcaggg tgccacgggc ggcgaccacg gccaccagca ggcagaccat
    13801 gaacaccgct acacgtccgt accacggggc gatctggcgc gtgccgatgc tgccaccgct
    13861 gaacgggccg cgcggacggg tcgcccggtc ggcgcccttg aacgccaggc tcaggatgat
    13921 cgtgccgccg acccaggcca gcaggtagcg caccaccggg aagccgtacc agagcatgct
    13981 catcacggtc ttcgggtctt cctttacata ctggaagacc aggccgttga ggcgctggtg
    14041 gaattcacgg tagaagtcca tctccatcag gcccaggaac aaggcgatgc tggaggtgac
    14101 cgtcagccag aaacgaaaga acccacgtgc cgccatggcc ctggcgctga acaacgccag
    14161 cagcaatgga atgcagaggt agaccaccag gcgcaggtcg aatcgcaagc cgttgacgaa
    14221 cgcttcgaca aaggtagagg ccggggtgtc gaggatcatc tcgcggttgt agaccagcag
    14281 cgcaacgcgc agcaggctga acatgaccat catcaccagg gcgcaaagca gggtgtaggc
    14341 caggtgcgat ttgacggtcg gttgcagcag gcgatgcgta gtgcgctgct gactcagggc
    14401 gtccgggatt gccatgtcgt tttaggacct attggagttt gagtgacaaa aaggaacaac
    14461 ggcgcgccct ctgttggcca atgcctggcc ccggggcttg cgcgagtgcg caaatgtttg
    14521 cacgaacggc catggcattg ccattaaata accggccgcg ataaaagcgc gggggattgt
    14581 ccgcaaggtt ttgtgaaaat tttgttcaat gaatattcag aaacacaaaa tccccggtgc
    14641 tacgcatagg cgagacggac tcattgtggc gaaggaactt gctcgcgcga agctgcgcag
    14701 cagtcgcaaa accgaccaaa tgagacatgc ctgatcaagc gcggtgactg gattgggctg
    14761 cttcgccgcc cagcgggagc aagctccctc gccacagaat gcacctttgc ctcagaaagc
    14821 tctccccaga gagattctta gcgattagtg aaactgccgc cccaaccccg ccggcacgcc
    14881 ctcgatgg
//
