LOCUS       c00011_3300027..       10801 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027111.a:Ga0209281_1000015.
ACCESSION   c00011_3300027..
VERSION     c00011_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 12:02:49
            Original ID  :: 3300027111.a:Ga0209281_1000015
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 58227
            Orig. end    :: 69028
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10801
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[63227:64028](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5801
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     cand_cluster    1..10801
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10801
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /region_number="1"
                     /rules="AfsA"
                     /tool="antismash"
     CDS             complement(24..947)
                     /gene_functions="regulatory (smcogs) SMCOG1031:LysR family
                     transcriptional regulator (Score: 324.6; E-value: 9.8e-99)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg11_42"
                     /transl_table=11
                     /translation="VDSLSGVTSFVKTAEALSFISAARALGISASAVGKNVAKLEASLN
                     VRLLHRSTRKVSLTAEGQLFYERCRKILDDLEDAQAMLSHATQEPRGKLRVSLPTIGYR
                     FLLPHMTRFRKTYPDIELELDFNDQLVDVIDEGFDVVIRSGGQADSKLMARKLGPFKFV
                     LCASPDYLQRKGRPTAISDLEHHECLRYRFVTTGKIMDWSMSAAPEFVQLRLPTALTLN
                     NMEAMLMAVVDGHGIAFVPDFLAREAIAQGRLETLLDGHSEDQGQFWALWPSSRHLSPK
                     IRVFVDFAAEHLFANPPLEGPGTARS"
     CDS             1092..2645
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 279.1; E-value:
                     8.3e-85)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_43"
                     /transl_table=11
                     /translation="MNSATEPLPTRGRYSILAAICLAALVLPMSFTGGAVATPFIGQTF
                     DAHPTELAWITNAFMLSFGSLLMAAGTLADLYGRKLVFMCGIALFALVSILLAVVPDMI
                     WLDLLRGVQGIAAAAALASGSAALAQEFDGHARTRAFSLLGTTFGVGLAFGPLVSGLLI
                     ESMGWRSIFLCTALLAILSLIFALPKMRESRDPQAQRLDTPGVLTFSGLLVAFTTAVIL
                     APEQGWGSPVIQALFGAAAVFLLLFIIVENRAKHPMLELGLFLFPRFVGVQILPIGTCY
                     CYIVLIVLLPFRFIGVEGASAFEAGLMMLALSAPMLVIPMIAASLTRWLSAGVLCAIGF
                     VIAAVGLYWLSVIPAGEHGQILAAMLLTGIGTGLPWGLMDGLSVSVIPKERAGMAAGIF
                     NTTRVASEGVALAITVAVLTALVAHHLSLNASVKLPVADYSTIAQRLVMGDLQHASTSA
                     SQIPLTMLRSAYTAGFKTLLQLLAIFTLLTATVVFLFLGRQSEVGTESTTDAVRFSSDS
                     "
     CDS             2669..3862
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 79.3; E-value: 3.8e-24)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_44"
                     /transl_table=11
                     /translation="MSSNTHFTPLILAGIAALCGLSVANVYFNQALLPVFAGAMSIDAG
                     QTSWIATASQMGYALGILLIVPLGDRVAPLRLCRVLLAWTAAMLLLASQATQLSFLAGV
                     SFLICMGTCIPQVLLPYLAGLATAGERSRVIAWIQTGLVIGILLSRAIAGWLADHLGWH
                     SVYWVAACVMALCALVLPRILPQRHAPGIPVAYGRLLSSMLHLFWHEPLLRLSCALGAA
                     VFAAFSAFWSVIAFKLMGPPHNMNATEVGLFSLWGALATLLTPAAGKLCERFGTVAISL
                     ASIALCCLSFVLSMAWANLFIVLLACANLLSFALQLGQVANQTRIFSLSPESRSRLNTV
                     YMVCNFCGGAFGSALGGYLWLRFGWTGCATLGLLCAVLAMVALLAILRPRSKQLSVV"
     CDS             complement(4088..4189)
                     /locus_tag="ctg11_45"
                     /transl_table=11
                     /translation="MFVPDCSAKLESAWFSEKTVYCEQLYFRVFQSG"
     CDS             4234..4989
                     /NRPS_PKS="Domain: Thioesterase (11-229). E-value: 8.4e-32.
                     Score: 103.1. Matches aSDomain:
                     nrpspksdomains_ctg11_46_Thioesterase.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 165.2; E-value: 2.3e-50)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_46"
                     /transl_table=11
                     /translation="MMLIDSEKVCVFIPFAGGSGLSFEALRRAVGTDMPVTGVTYKRRY
                     QKDVTQAPGTVEAMANEVIALIDNLAAREVIVFGYSLGAIVAYEVARRQHEFGPHLIKL
                     VVAACRAPHLFNCAQVTLDDSEEVFLKTVAKFGIIPDFMFKDSAAKHRMLPSLIKDFQA
                     AASYRHLPGEPLGLPMTVLGGSQDPFAPVQDVMAWKEHSQDSIRLEFFEGNHFFLTQHV
                     PAITRVITEPVSPVTRQPVSSQYLDSVSL"
     aSDomain        4267..4920
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg11_46_Thioesterase.1"
                     /evalue="8.40E-32"
                     /label="ctg11_46_Thioesterase.1"
                     /locus_tag="ctg11_46"
                     /protein_end="229"
                     /protein_start="11"
                     /score="103.1"
                     /tool="antismash"
                     /translation="FIPFAGGSGLSFEALRRAVGTDMPVTGVTYKRRYQKDVTQAPGTV
                     EAMANEVIALIDNLAAREVIVFGYSLGAIVAYEVARRQHEFGPHLIKLVVAACRAPHLF
                     NCAQVTLDDSEEVFLKTVAKFGIIPDFMFKDSAAKHRMLPSLIKDFQAAASYRHLPGEP
                     LGLPMTVLGGSQDPFAPVQDVMAWKEHSQDSIRLEFFEGNHFFLTQHVPAITRVIT"
     aSModule        4267..4920
                     /domains="nrpspksdomains_ctg11_46_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="ctg11_46"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       4459..4512
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg11_46_0001"
                     /evalue="3.50E-07"
                     /label="NRPS-te1"
                     /locus_tag="ctg11_46"
                     /protein_end="93"
                     /protein_start="75"
                     /score="22.7"
                     /tool="antismash"
                     /translation="IVFGYSLGAIVAYEVARRQ"
     CDS             5001..5801
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_47"
                     /sec_met_domain="AfsA (E-value: 1.3e-12, bitscore: 42.8,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELSVSSSVSSCPFSGFSPLSSHQQEPPRHYVVVGDRIKSQCSD
                     NLFISVTAAEEMVAQLAESEKLTLHVGQGVTDEQLNTLYGFKEALAPTLNILPVEHPPR
                     ASSSATHKLKSHNIAISAPWENGNGTYSASLMIDDANAELSDHLTGQHVSGMMVIEAAR
                     QMTIAVAEAYYVTPAAKGKVNFVTNKMDVTYRDFLLPIHTEILCIPVELRRSGASNFRF
                     GCRLEFKQQNQCLVVLGFELSVIDSRYFQLKEAQLLHQFVKRLA"
     CDS             5823..6128
                     /locus_tag="ctg11_48"
                     /transl_table=11
                     /translation="MKEQVLSIIYNAIENENHSLAQPISLEQGEDTALYGAGGVLDSMS
                     LVSIVIDVEQMLEEQLGVKMTLVNDSAMSPKRSPFQSVSTFANYILELNAQVPHGR"
     CDS             6118..6822
                     /NRPS_PKS="Domain: PKS_KR (6-156). E-value: 8.6e-09. Score:
                     27.3. Matches aSDomain: nrpspksdomains_ctg11_49_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     185.6; E-value: 1.9e-56)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_49"
                     /transl_table=11
                     /translation="MDDKKPVTLITGTRKGIGRHLAEYYLAQGHRVIGCSRSSSDLTHS
                     SYDHFIADVADEQAIGELMKHVRGTCGRLDHLINNAGIASMNHSLLTPYKTAQNIMQTN
                     VLGTFLLSREAAKLMRAGRQGRIVNFSTVAKPLKLEGEALYAASKAAVETLTCVMAKEL
                     ASFGITVNALGPTPIDTDLTRVIPAQKMKDLLAQQSLKRFGTFDDVTNVTDFFLSSRSH
                     FITGQVVYLGGL"
     aSDomain        6136..6585
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg11_49_PKS_KR.1"
                     /evalue="8.60E-09"
                     /label="ctg11_49_PKS_KR.1"
                     /locus_tag="ctg11_49"
                     /protein_end="156"
                     /protein_start="6"
                     /score="27.3"
                     /specificity="KR stereochemistry: C2"
                     /specificity="KR activity: inactive"
                     /tool="antismash"
                     /translation="VTLITGTRKGIGRHLAEYYLAQGHRVIGCSRSSSDLTHSSYDHFI
                     ADVADEQAIGELMKHVRGTCGRLDHLINNAGIASMNHSLLTPYKTAQNIMQTNVLGTFL
                     LSREAAKLMRAGRQGRIVNFSTVAKPLKLEGEALYAASKAAVETLTC"
     aSModule        6136..6585
                     /domains="nrpspksdomains_ctg11_49_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg11_49"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       6142..6231
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg11_49_0001"
                     /evalue="1.90E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg11_49"
                     /protein_end="38"
                     /protein_start="8"
                     /score="10.9"
                     /tool="antismash"
                     /translation="LITGTRKGIGRHLAEYYLAQGHRVIGCSRSS"
     CDS             6851..7105
                     /NRPS_PKS="Domain: PP-binding (3-70). E-value: 2e-09.
                     Score: 29.6. Matches aSDomain:
                     nrpspksdomains_ctg11_50_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_50"
                     /sec_met_domain="PP-binding (E-value: 2.2e-08, bitscore:
                     29.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLDAIKKELAELLELRESELQADVLLHPLSNWDSLTKVTLLGVL
                     NDQFGFALSPALLDEVETIGELFDAIQADAAHVRVGEPS"
     aSDomain        6860..7060
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg11_50_PP-binding.1"
                     /evalue="2.00E-09"
                     /label="ctg11_50_PP-binding.1"
                     /locus_tag="ctg11_50"
                     /protein_end="70"
                     /protein_start="3"
                     /score="29.6"
                     /tool="antismash"
                     /translation="DAIKKELAELLELRESELQADVLLHPLSNWDSLTKVTLLGVLNDQ
                     FGFALSPALLDEVETIGELFDAI"
     aSModule        6860..7060
                     /domains="nrpspksdomains_ctg11_50_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg11_50"
                     /tool="antismash"
                     /type="unknown"
     CDS             7102..8121
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 238.9; E-value: 1.2e-72)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_51"
                     /sec_met_domain="fabH (E-value: 1.4e-54, bitscore: 180.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNAAIDGVSIRALSAAIPEDVMTLDDFATLFGEKEVQRIAKSTGI
                     HQVRVANRLSTVDLCAAAAQALFNAADIDPASIDGLVLVTQTPDSLMPASSALLADRLG
                     LGNALAAFDLNFGCSGYIYGLFQAAMLIKAGGCRRVLVCTGDVISKLLNPEDRHVRLVF
                     GDAATCTLLEDGDQTLGFAFTTDGAGAQYLNTTLDYTPSATSRVQAAGLHMDGGQVMNF
                     ALEKVPSAINAFIRDQGIDPERVPFFLLHQANKFMLDYLAKKLGVASSKVPIEVADVGN
                     TGPSSIPLMICKRHGREDLRQDNLIACGFGVGLSIGTARLSLRDAHIIAPVTVPAFPN"
     CDS             8145..8819
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 66.7; E-value: 3.9e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_52"
                     /transl_table=11
                     /translation="MTIQAIWFDFGGVLSPSIDELYRVYQQNTGISRIQMEAAMHAVAK
                     PLNVQFQAPIELAMMTQVEWGQGMSKALSELYPGIDLSRCDFDNHGEQWFSPHSVNEHM
                     FELFHEVKAAGLKACILTNNVVEWETPWRRMVGLDDVADSIVDSCKVKLRKPDPKIFAL
                     AADRIGVPAASCVLIDDVEENCEAARAAGWHAILFVDSHQTQQAVRALIGEAQPRAQAG
                     AR"
     CDS             8816..10012
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 274.6; E-value: 2.2e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_53"
                     /sec_met_domain="p450 (E-value: 4.5e-17, bitscore: 57.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMRVHPSVLDIPNLDAAPYYQAVGWQDQLPQIKLPSGHVAIHLT
                     GYADCKAFLADPSISRTLCNIEDGPTFLPGPTQPELLLNLDNPAHMRSRATVTRAFSKR
                     GLESVRQHVTTVTVESIEQMRQGVTPPDLFASVLERLTSSTVCHILGIPEEDRLLFRPW
                     SQMIQSAPPDDIVGIEVAVKASFDYMLDFVQGRREAHPDGFIRQYVDQRHTLEDPLSDR
                     EFVGVLLGILLGGDHNALSVMTKSLYTLLCAPSLWRYLRENPDRAPQLIEELIRLIPIG
                     KLSAFPRMTTQALQTSRGVIPANTTVYANVFLANRDPNVFNAPLLINPERQDKAAHMQF
                     GHGIHSCMGPALARLEIATVLSTLVQALPDLELACDPTSIRWINGTVLRRPDELPVRF"
ORIGIN
        1 ggctgctagg agcaggcaag gcttcacgag cgagctgtac ccgggccctc cagcggtgga
       61 ttggcaaaca ggtgctcggc ggcgaagtct acgaatacgc ggatttttgg cgaaagatga
      121 cgactggacg gccacagtgc ccagaattgc ccctggtctt cgctgtgacc atcgagcagc
      181 gtttccaggc gaccttgggc gatggcttcg cgcgccagga agtccgggac aaaggcgatt
      241 ccgtgcccat ccaccacggc catcaacatg gcctccatgt tgttcagcgt cagggcggtg
      301 ggcaggcgca actgcacgaa ctccggggcg gcagacatgc tccagtccat tattttgccc
      361 gtcgtgacaa atcgataacg caagcactcg tggtgttcga ggtcgctgat cgcggtgggc
      421 cgtcccttgc gttgcaagta atcgggtgac gcgcacagga caaacttgaa aggccccagc
      481 tttcgcgcca tcaacttcga gtcggcctgg ccgccgctgc gaatcaccac gtcaaagccc
      541 tcatcgatca catccaccaa ttgatcgttg aagtccagct ccagctcgat gtccggatag
      601 gtcttgcgga accgcgtcat gtgcggcaac agaaagcgat agccaatggt gggcaggctc
      661 acgcgcagct ttccgcgggg ctcctgcgtg gcgtgggaca gcatcgcctg ggcgtcttca
      721 aggtcgtcga ggatctttcg gcagcgttca tagaacagct gtccttcggc tgtcaggctg
      781 actttgcgcg tgctgcggtg cagcagccgc acattcaacg aggcctccag tttggccacg
      841 ttcttgccca cggcggaggc ggaaatcccc aacgccctgg cggcactgat aaaactcagc
      901 gcctcggcgg tttttacgaa agaggtcacg ccactgagac tgtccacgaa tcgattacat
      961 ccttttagtt cattataagt ggaataaaag cccgtttatc ttcaattgta tcctaactag
     1021 agtgtacgaa acgatcgcgc gccttagcct ggacagcacg gatacttcaa agacatgcag
     1081 ggaatgacgt catgaactca gctaccgaac cgctgccgac ccggggccgg tattccatcc
     1141 tggctgccat ttgcctggca gccctggtat tgcccatgag ctttaccggc ggggcagtgg
     1201 ccacgccgtt cattggtcag accttcgatg cccatcccac cgaactggcc tggatcacca
     1261 acgccttcat gctcagtttt ggcagcctgt tgatggcggc cggcacgctc gccgacctct
     1321 atgggcgtaa gctggtgttc atgtgcggta tcgcgctgtt tgcgttggtg tcgatcctgt
     1381 tggcggtggt gcccgacatg atctggctgg acctcttgcg tggcgtacaa ggcatcgccg
     1441 cggcggctgc gttggccagc ggttcggcgg ccctggccca agagttcgac ggacatgcca
     1501 ggacacgtgc gttcagcctg ctgggcacca cgtttggcgt tggcctggcc ttcggcccgt
     1561 tggtatcggg tttgctgatc gagtccatgg gctggcgcag catttttctt tgcaccgcct
     1621 tgctcgccat tctttccttg atctttgcgc tgcccaaaat gcgcgaaagc cgcgacccgc
     1681 aggctcagcg cttggatacg cccggcgtgc tgacgttttc cggcctgttg gtggccttca
     1741 ccacggcagt gatcctggcg ccggagcagg gctggggttc gccggtcatc caggccctgt
     1801 ttggcgcggc ggcggtcttc ttgctgctgt tcatcattgt tgaaaatcgg gcgaagcatc
     1861 cgatgctgga actgggcttg ttcctgtttc cgcgttttgt cggcgtacag atcctgccga
     1921 tcggcacctg ctattgctac atcgtcttga tcgtactgct gccgtttcgg tttatcggtg
     1981 tggagggggc cagtgccttt gaagcggggt taatgatgtt ggccctgtcc gccccgatgc
     2041 tggtgatccc catgatcgcc gcgtcgctga cccgctggtt gtccgcgggc gtgctgtgcg
     2101 ccattggttt cgtgatcgcc gcggtggggc tctactggct cagcgtgatc ccggccggcg
     2161 aacacgggca gatcctcgcg gccatgttgc tgaccgggat cggcacagga ctgccctggg
     2221 gcctgatgga tggcttgtcg gtcagcgtga tccccaagga acgagccggg atggccgccg
     2281 gtatcttcaa cacgacacga gtggccagcg aaggcgtcgc cctggcaatc actgtcgccg
     2341 tgctgacggc gctggtcgcg caccacctga gcctcaatgc ctcggtcaag ctgcctgttg
     2401 ctgattattc aacgatcgcg caacggctgg tcatgggcga tctccagcac gccagcacca
     2461 gcgccagcca gatccccttg acgatgctgc gctcggccta caccgcaggc ttcaagacct
     2521 tgctgcaact gctggcgatc ttcaccttgc tcactgccac tgtggtcttt ctgtttttgg
     2581 gacgccaaag cgaagtcggt accgagtcca cgaccgatgc cgtgcgattt tcatcggata
     2641 gctgaaaact gctttggagt tatgggtaat gtcgtccaac acacacttta cgccgctgat
     2701 tttggcgggc attgccgcat tgtgcggctt gtcggtggcc aacgtttact ttaaccaagc
     2761 actgctgccg gtgtttgccg gtgcgatgag cattgacgcg gggcagacca gttggatcgc
     2821 cacggcatcg cagatgggct atgcgctggg gatattgctg atcgtcccgt tgggcgacag
     2881 ggtggcgccc ttgcgactgt gccgcgtgct gctcgcgtgg accgcggcca tgctattgct
     2941 ggccagccaa gccacccaac tttcgttcct ggcgggcgtc agcttcctga tctgcatggg
     3001 tacctgcatt ccgcaggtac tgctccctta tctggcaggt ctggccactg ccggcgaacg
     3061 cagtcgcgtc attgcctgga tacaaacggg tttggtcatc ggaatcctgc tgtccagggc
     3121 cattgctgga tggttggccg atcaccttgg ctggcactcg gtgtattggg tggcggcttg
     3181 cgtcatggcc ctgtgcgcgc tggttctgcc gaggattctg cctcagcgtc atgcgcccgg
     3241 aataccggtt gcctatggcc gactcctgag ttcgatgctg caccttttct ggcatgaacc
     3301 gttgctgcgc ctgtcttgcg ccttgggcgc cgccgtgttt gccgccttca gtgcgttctg
     3361 gtcggtcatc gctttcaagc taatggggcc accccacaac atgaatgcca cggaggtcgg
     3421 cctgttcagt ctgtggggcg ccctcgccac gttgctgacg ccggcggctg gcaaactgtg
     3481 tgaacggttt ggcacggtcg ctatcagcct cgcttctatt gcgctgtgtt gcctgagctt
     3541 cgtcttatcg atggcctggg ccaatctgtt cattgtgctg ctggcgtgcg ccaacctgct
     3601 cagctttgcc ttgcagctgg ggcaggtggc caaccagaca cggatttttt ctctgagccc
     3661 ggaaagccga agccgcttga acaccgtgta catggtctgc aatttttgtg gtggggcatt
     3721 tggcagtgcc ttgggtgggt atctttggct gcgattcgga tggaccggat gcgccactct
     3781 gggattattg tgcgccgtat tggcaatggt cgccttgctg gcgatcctaa ggccgcgctc
     3841 caaacaactt tcggtcgtat agccattgag tgaccggtcg tccacgttcg taacttgtta
     3901 ttccttcctt gtactgatta gttgtatggg tgctcgcatc aatacagcta tctgctgttc
     3961 ttcgtgatac ctccctcccc ttaaaattcc tgtcatgttt ttacccgtcc gttcgccatc
     4021 tcctgtaatg gctttttaat atgcgcggat attgaactta tagttcagac agttgagccg
     4081 aaaacgctca accgctttga aatactctga aatacaattg ctcgcagtaa acggtttttt
     4141 cggaaaacca ggcagactcc aacttggcag aacagtcggg gacgaacatt agtttcctga
     4201 gctttttttg atctctcaaa caaggagtct tcgatgatgc tcatcgactc tgaaaaagtg
     4261 tgtgtgttca taccgttcgc cgggggcagc ggcttgtcgt ttgaagcgtt gcgacgtgcc
     4321 gtgggtactg acatgccggt gacgggtgtc acttataaac gtcgctatca aaaagatgtc
     4381 acgcaggcac ccggtactgt cgaggccatg gcaaatgaag tcattgcgct gatcgacaac
     4441 ctggcggcgc gcgaggtcat tgtttttggt tacagcctgg gggccattgt tgcgtatgag
     4501 gttgctcgtc gccagcatga atttggcccg catttgatca agttagtggt agctgcctgc
     4561 cgtgcgccgc acctctttaa ctgcgcacag gtaacactag acgattcaga agaggtattc
     4621 cttaaaacgg ttgccaagtt tggaattatt ccggatttca tgttcaagga ttcggcagcc
     4681 aagcaccgca tgctgccttc cttgatcaag gatttccagg cggcagcctc ataccggcac
     4741 cttccgggcg agccgttggg ccttcccatg acggttttag gcggtagcca ggatcccttt
     4801 gcaccggttc aggatgtgat ggcctggaag gagcatagtc aagattctat tcggctggag
     4861 ttctttgagg ggaaccattt tttcctcacc caacatgtgc ctgccatcac ccgagtgatt
     4921 accgagcctg tcagtccggt gacacgtcag cctgtttcat cccaatacct ggattctgta
     4981 agcctataaa ggtgaaaaaa atggaagagc tcagtgtctc aagcagtgtt tcttcgtgcc
     5041 cgttttctgg attttccccg cttagttcac atcagcagga accgcccagg cattacgtcg
     5101 tagtgggaga taggataaaa agtcagtgca gcgacaatct atttatatcg gtgacagcgg
     5161 ccgaagaaat ggttgctcaa ctcgctgaaa gcgaaaagtt gaccttacat gttggtcagg
     5221 gtgttaccga tgagcaacta aacacgctgt acggattcaa ggaggcgttg gcgccgacat
     5281 tgaatatcct tccggtggag catcccccgc gcgcctcttc aagtgctacg cacaaattga
     5341 agagtcataa cattgccatc tccgcgcctt gggaaaatgg taatggcact tattctgctt
     5401 cgttaatgat cgatgatgcc aatgctgagc taagcgatca tctgaccggc cagcatgttt
     5461 ctggaatgat ggtcatcgag gctgcacgcc aaatgaccat cgccgttgca gaggcctatt
     5521 acgtaacccc ggcggccaaa ggcaaagtca actttgtgac caacaaaatg gacgttacgt
     5581 atcgggactt tctgctgccg atacacaccg aaatcctgtg tattccggtg gagctgcgcc
     5641 gctcgggcgc ctcgaatttt cgttttggct gccgccttga gttcaaacaa caaaaccagt
     5701 gcctggtggt gcttggcttt gaattatcgg tgatcgactc gcgctacttt caactcaagg
     5761 aagcgcaact tcttcatcaa ttcgtcaagc gtctcgcctg atccactttt gagagagtcc
     5821 ctatgaaaga gcaagttctc agcattattt ataatgcgat tgaaaatgaa aaccacagtc
     5881 tcgcccagcc catcagcctg gaacaaggcg aagacaccgc cctctacggt gccggcggtg
     5941 tcctcgattc catgagcctg gtgtccattg tgattgacgt cgagcagatg cttgaggaac
     6001 agctgggggt caagatgacg ctggtcaacg acagcgccat gtcccccaag cgcagtccgt
     6061 tccagtcggt aagcaccttc gccaattaca ttcttgaact gaatgctcag gtgccccatg
     6121 gacgataaaa agcctgtcac gcttatcacg gggacacgca aggggatcgg caggcatctg
     6181 gccgagtatt accttgctca ggggcatcgc gtaatcggct gcagccgttc atccagcgat
     6241 cttacccatt caagctacga ccactttatt gcggacgtgg ccgatgagca ggccatcggc
     6301 gagctgatga aacacgtgcg tggcacctgc ggccggcttg atcacctgat caacaatgcc
     6361 ggcatcgcca gcatgaatca ctcgctgctg acgccctaca aaaccgcgca aaacatcatg
     6421 caaaccaatg tgctgggcac attcctgctc agccgggaag cggcaaagct catgcgcgcc
     6481 gggcgtcagg gacgcattgt gaatttttcc acggtggcca agccgctgaa gctggaagga
     6541 gaggcgctgt acgccgcgtc caaagccgct gtggagaccc tgacctgtgt aatggccaag
     6601 gagctggcca gttttggcat caccgttaat gcgctgggcc ccacgccgat cgataccgat
     6661 ctgacgcggg tcatccccgc acaaaaaatg aaggacctgc tggcgcagca gtcgctgaag
     6721 cgcttcggca cgttcgacga cgtgaccaat gtgacggact ttttcctgtc ttcgcgcagc
     6781 catttcatta ccggccaagt cgtgtatctc ggcggcctct aactcagctc tcctgcaaaa
     6841 ggacttcacc atgaacctgg acgccatcaa gaaagaactc gcagaactcc tggaactgcg
     6901 cgaatcggaa cttcaagccg atgtattgct gcatcccctg agcaattggg actcgttgac
     6961 caaggtcacg ctgctggggg tgttgaatga ccagtttggt tttgccttga gtccggcact
     7021 gctcgatgag gtggaaacca ttggagaact gttcgacgcc atccaggccg atgcggcgca
     7081 cgttcgtgtc ggtgagcctt cgtgaacgcg gccatcgatg gagtgtccat ccgcgcgcta
     7141 tcggctgcca tccctgaaga cgtcatgacc ctggacgatt tcgccacgtt gtttggtgaa
     7201 aaagaggtgc agcgaatcgc caagagcacc ggcatccatc aagtgagggt ggctaaccgc
     7261 ttgtcgacgg tggacctctg cgctgcggct gcccaggcgt tgttcaatgc cgcggacatc
     7321 gaccccgcca gcatcgatgg cctggtgctc gtcacgcaga cgcccgatag cctgatgccg
     7381 gccagcagtg ccttgctggc ggatcgcttg gggttgggaa acgcgctcgc ggctttcgac
     7441 ctcaacttcg gttgttccgg ctacatctat ggcctctttc aggcggccat gctgatcaag
     7501 gccggcggtt gccgcagggt gctggtgtgt accggcgatg tgatcagcaa actgctcaac
     7561 cctgaagacc ggcacgtgcg gcttgtcttc ggcgatgcag cgacgtgcac gctgctggag
     7621 gacggcgatc agacgctcgg atttgcattc acgaccgatg gcgctggcgc gcaatacctc
     7681 aacacgactc tggactacac gcccagcgcc accagccggg tacaggccgc agggctgcac
     7741 atggacggtg gccaagtgat gaactttgcc ctggagaaag tgccgtcggc gatcaacgcc
     7801 ttcattcgcg accaaggtat cgaccctgaa cgtgtgccgt tcttcctgct gcatcaggcg
     7861 aacaagttca tgctcgatta tttggccaaa aaactgggtg tcgcgtcctc caaggtcccc
     7921 atcgaagtgg ccgacgtggg caataccggt ccttcgtcga tcccgctgat gatctgcaag
     7981 cggcacggcc gcgaggattt acggcaggac aacctgattg cctgtggctt tggcgtcggg
     8041 ttgtccatcg gaacggcccg tttatccctg cgcgatgccc acatcatcgc acccgtaaca
     8101 gtacccgcct tccctaactg agctgacaat caaggaaaga tcccatgact atccaagcaa
     8161 tctggttcga cttcggtggt gtgttgtcgc cttccatcga cgagttgtac cgcgtctatc
     8221 agcaaaatac cggcatcagc cgcattcaga tggaggccgc catgcacgcc gtggccaagc
     8281 cgctgaatgt gcagttccag gcgcccatcg agctggccat gatgacccag gtcgaatggg
     8341 ggcagggcat gagcaaggca ttgtccgagc tgtatccggg aatcgatttg agccgttgcg
     8401 atttcgataa ccatggcgag cagtggtttt ccccgcacag cgtcaacgag cacatgttcg
     8461 agcttttcca tgaggtgaaa gccgcaggcc tcaaggcgtg catccttacc aacaacgtcg
     8521 tggagtggga gacaccttgg cggcgcatgg tgggcctgga tgatgtcgcg gacagcatcg
     8581 tcgattcctg caaggtcaaa ctgcgcaagc ctgacccgaa gatttttgcc ctggccgccg
     8641 atcggatcgg tgtaccggcc gccagctgcg tgctgatcga cgatgtcgag gaaaactgcg
     8701 aagccgcgcg agccgccggc tggcacgcca ttctgtttgt cgacagccac cagacccagc
     8761 aagccgtgcg tgcgctcatc ggcgaggcac aaccccgtgc acaggcaggt gcccgatgaa
     8821 catgcgcgtc catcccagcg tgctggatat ccccaacctc gatgccgcac cctattacca
     8881 ggccgtgggc tggcaggatc aattgccgca gatcaagttg cccagcgggc acgtcgccat
     8941 tcatctgacc gggtacgccg actgcaaggc atttctggct gacccgagca tcagtcgaac
     9001 cctgtgcaac atcgaagacg gcccgacttt tctccctggc ccgactcaac cggaactgtt
     9061 gctcaacctg gacaacccgg cccacatgcg ttcgcgcgcg accgtcacgc gggctttcag
     9121 caaacgtggc ctggagagtg tgcgccagca tgtgaccacg gtaaccgtcg agagcatcga
     9181 gcagatgcgc caaggggtga cgccgccgga cctttttgct tcggtgctgg agcggctgac
     9241 gtcatcgacg gtgtgtcaca tcctgggcat tcccgaagaa gaccggctgc tgttccggcc
     9301 ttggagccag atgattcaat cggctccgcc ggacgatatc gtgggcatcg aggtggcggt
     9361 caaagccagt ttcgattaca tgctggactt tgtgcagggc cgccgggagg cacatccgga
     9421 cggatttatt cgccaatatg tcgaccagcg ccacaccttg gaagacccgc tgagcgatcg
     9481 ggaatttgtc ggggtgctgc tggggattct gttggggggc gaccataacg ccttgagcgt
     9541 catgactaaa agtctctaca ccttgttgtg cgcgccgtcg ctgtggcggt acctgcgcga
     9601 aaaccccgat cgcgcaccgc agttgatcga agagctcatt cgattgattc ccattggcaa
     9661 gctatcagcg ttcccgcgga tgaccaccca ggctctgcaa accagccgcg gtgtgattcc
     9721 cgcgaatacg acggtgtatg ccaacgtgtt cctcgccaac cgcgacccca atgtgttcaa
     9781 cgctcctttg ctgatcaatc ccgagcgtca ggacaaggct gcgcatatgc aatttggcca
     9841 tggcatccac agctgcatgg ggccggccct ggcacgcctg gaaatagcca cggtgctgtc
     9901 gacccttgta caggcgttac ccgacctgga actggcctgt gacccgacgt cgatccgctg
     9961 gatcaacggt acggtgctgc gccgccccga cgaactgccc gtgcgtttct gatgccattt
    10021 caatcaaggg aaaaaagcca tgatctttaa accgctgata aacggatttg cgcagttttc
    10081 gaatcagatc tttctgaatg accctgaaca gtcctacaca tatgcccagt tgaacgacga
    10141 aatcggtgtc caattggagt ggctcgccgg tcatggcgtg gccaggcaag cggtggtttt
    10201 catgaatggg gacttttcgt tcacaggcat cgcgctgttc ctggcgctgt accagaacgg
    10261 caacattatt gccctgaaca ccgctgaaaa cccggcggaa attcaaaaca agcaggcggc
    10321 ggcaaacccc gagttcgtga ttgatatcga agcccgccag atccgggctt gtaccgttgc
    10381 ccaagctccg caaaacccca tgatcggtga gcttaaaaaa caggcgcatg cgggcctgat
    10441 tctgttcagc agcggcacca ctggcaaacc caaggcgatg ttgcacgacc tcgaccgatt
    10501 agtgggtgag tttgccgata agcgatcgcg tcgtctcgat atctttctgt tcctgttgtt
    10561 cgatcatatt ggtggcatca atacgctgtt gaacattctt tccattggcg gaacggccac
    10621 gatcgccgcc agcaaaacgc cggacaccgt tgccagcctg attgaaaagc accgcattac
    10681 cgtgctgccg acttcaccca ctttcttgaa cctgatgctg atcaaccaag tgctcgatac
    10741 ctacaacctc agcagtttgc gcatgatcac ctatggcacg gagccgatgc cggagagctt
    10801 g
//
