LOCUS       c00261_3300027..        9873 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027262.a:Ga0209303_1002370.
ACCESSION   c00261_3300027..
VERSION     c00261_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 12:36:47
            Original ID  :: 3300027262.a:Ga0209303_1002370
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9873
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9873
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2792](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..2792)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..9873
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9873
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS             complement(3..2792)
                     /NRPS_PKS="Domain: PKS_KS(Enediyne-KS) (15-489). E-value:
                     8.3e-92. Score: 300.0. Matches aSDomain:
                     nrpspksdomains_ctg261_1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (615-911). E-value: 2.5e-62.
                     Score: 202.6. Matches aSDomain:
                     nrpspksdomains_ctg261_1_PKS_AT.1"
                     /NRPS_PKS="type: Type I Enediyne PKS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 230.7; E-value:
                     5.3e-70)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg261_1"
                     /sec_met_domain="PKS_AT (E-value: 2.5e-63, bitscore: 202.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 3.8e-184, bitscore:
                     600.8, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSNAISVDISSAAKIAVIGMGCCYPGAKNLKTLWENILGRRRQF
                     RTLPERRIPLSEYYASDPKSPDQTYGKQAALIDGFEFDWAAWRIPKTTFDRTDIVHWLA
                     LDTAYQALKDAASCAGRAEDFSSASMLMKSHNVSTQTMGVIVGNTLTGEQTRASTLRLR
                     WPYVRRAVQAAATVHGISTAAAQALMETLEAIYKSPFASITEDSLAGGLANTIAGRICN
                     AFNLDGGGYIVDGACASSLIAVKTAATALAAGELDCALAGGVDVSLDPFELIGFAKTGA
                     LTAGDMAVYDQAANGFLPGEGCGFVVLKRLADARADGDYIYATLQGWGISSDGKGGITA
                     PSGQGQAKALQRAYDQAGYRPCEVDFIEGHGTGTAVGDRAELEGIAAVVHANGDVTPRS
                     VGVTSFKSIMGHTKAAAGIGGLIKAVMAVNQRIIPPTAGCQNPSAVFESLALGVYPVLT
                     GAVRSSTSQLRAGVSAMGFGGINSHITLASADAPAAHLKPTVDERALLVSPQETELIVL
                     SGDSISGLLARIAAIRQAATGISDAELADLAVHLTTFLHPTHALRAAVVARSPEALIEQ
                     LQQLEQYLVDHPIGPGEMASVPPQGFWVANALQQDRVGFLFPGQGSQRLNMARTLVERY
                     GWARDLVTQLDTQLQKMGAQSVSPLIYRPVEQAANPAEIQTWTQELAQTHVAQPALCLT
                     SLLWSGYLDRLGIQPVAVGGHSLGELTAFHRAGAFDVETLLHLAAVRGQAMSAGRTGGA
                     MASLGCSADIAQSLLACIEDDVAIANINSPEQTVISGTSSGIASVMQLAISQGIQVRQL
                     PVSNAFHSSFVAGAADQLRTDAPLPDVLENLSLALFSSMNGAQVQSGLNLRNHFADQVT
                     SSIDFVALVQAMAPQCDLLVEVGAGRVLSGLANATIQATGPECLPLESKAGCDRDLNAF
                     "
     aSDomain        complement(60..947)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg261_1_PKS_AT.1"
                     /evalue="2.50E-62"
                     /label="ctg261_1_PKS_AT.1"
                     /locus_tag="ctg261_1"
                     /protein_end="911"
                     /protein_start="615"
                     /score="202.6"
                     /specificity="Minowa: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="consensus: mal"
                     /tool="antismash"
                     /translation="LFPGQGSQRLNMARTLVERYGWARDLVTQLDTQLQKMGAQSVSPL
                     IYRPVEQAANPAEIQTWTQELAQTHVAQPALCLTSLLWSGYLDRLGIQPVAVGGHSLGE
                     LTAFHRAGAFDVETLLHLAAVRGQAMSAGRTGGAMASLGCSADIAQSLLACIEDDVAIA
                     NINSPEQTVISGTSSGIASVMQLAISQGIQVRQLPVSNAFHSSFVAGAADQLRTDAPLP
                     DVLENLSLALFSSMNGAQVQSGLNLRNHFADQVTSSIDFVALVQAMAPQCDLLVEVGAG
                     RVLSGLANATIQATGP"
     aSModule        60..2747
                     /domains="nrpspksdomains_ctg261_1_PKS_KS.1"
                     /domains="nrpspksdomains_ctg261_1_PKS_AT.1"
                     /incomplete
                     /locus_tags="ctg261_1"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(423..461)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg261_1_0004"
                     /evalue="2.20E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ctg261_1"
                     /protein_end="790"
                     /protein_start="777"
                     /score="11.4"
                     /tool="antismash"
                     /translation="ANINSPEQTVISGT"
     CDS_motif       complement(555..677)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg261_1_0003"
                     /evalue="9.80E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg261_1"
                     /protein_end="746"
                     /protein_start="705"
                     /score="40.1"
                     /tool="antismash"
                     /translation="GIQPVAVGGHSLGELTAFHRAGAFDVETLLHLAAVRGQAMSA"
     CDS_motif       complement(900..950)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg261_1_0002"
                     /evalue="5.20E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg261_1"
                     /protein_end="631"
                     /protein_start="614"
                     /score="18.8"
                     /tool="antismash"
                     /translation="FLFPGQGSQRLNMARTLV"
     aSDomain        complement(1326..2747)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg261_1_PKS_KS.1"
                     /evalue="8.30E-92"
                     /label="ctg261_1_PKS_KS.1"
                     /locus_tag="ctg261_1"
                     /protein_end="489"
                     /protein_start="15"
                     /score="300.0"
                     /tool="antismash"
                     /translation="IAVIGMGCCYPGAKNLKTLWENILGRRRQFRTLPERRIPLSEYYA
                     SDPKSPDQTYGKQAALIDGFEFDWAAWRIPKTTFDRTDIVHWLALDTAYQALKDAASCA
                     GRAEDFSSASMLMKSHNVSTQTMGVIVGNTLTGEQTRASTLRLRWPYVRRAVQAAATVH
                     GISTAAAQALMETLEAIYKSPFASITEDSLAGGLANTIAGRICNAFNLDGGGYIVDGAC
                     ASSLIAVKTAATALAAGELDCALAGGVDVSLDPFELIGFAKTGALTAGDMAVYDQAANG
                     FLPGEGCGFVVLKRLADARADGDYIYATLQGWGISSDGKGGITAPSGQGQAKALQRAYD
                     QAGYRPCEVDFIEGHGTGTAVGDRAELEGIAAVVHANGDVTPRSVGVTSFKSIMGHTKA
                     AAGIGGLIKAVMAVNQRIIPPTAGCQNPSAVFESLALGVYPVLTGAVRSSTSQLRAGVS
                     AMGFGGINSHITLASAD"
     CDS_motif       complement(1650..1697)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg261_1_0001"
                     /evalue="4.10E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg261_1"
                     /protein_end="381"
                     /protein_start="365"
                     /score="9.9"
                     /tool="antismash"
                     /translation="FIEGHGTGTAVGDRAEL"
     CDS             3776..5095
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 195.4; E-value:
                     2.2e-59)"
                     /gene_kind="transport"
                     /locus_tag="ctg261_2"
                     /transl_table=11
                     /translation="MDQQSPAIPEAPTPSSSVKPIRWKSPRCLGLALMCIGVAVGVKTW
                     GVTQETAAPRALLPVSTLSLQPSSFYNIQRSYSGEVQAHRTSELGFELTGTLIDIAVEE
                     GDWVNQGTLLARLDTRMLETQRQQLLAQKAQAQAQFRELKTGPRTEEIGAARAAVEDLG
                     QQLLLAQKQSQRRQNLYKKGAISRESFEERYFAAAALKKRQGQAQKRLEELLAGTRVEK
                     VEFQAAQLAEIDAQLDALKIQRSKSVLQAPFSGQVAQRLRDEGVVLNSGQPILRIVEAA
                     RVEARIGVPQTMAKEMRPGQTYPLHIGNQRYVGQVQTLLPEVDPQSRTVTVILAITGEA
                     ALPLGQTAKITLAQRQNQAGFWLPSTAIITGERGLWSAYVLKPSAQDAVFSVARRAVEV
                     LHTEGDRSYVRGMLKPQEQVIITGTRRIAPGQLVRVANSQ"
     CDS             5133..8264
                     /gene_functions="transport (smcogs)
                     SMCOG1049:AcrB/AcrD/AcrF family protein (Score: 762.5;
                     E-value: 1.1e-230)"
                     /gene_kind="transport"
                     /locus_tag="ctg261_3"
                     /transl_table=11
                     /translation="MFNLFYRNRQLLSLSITLIVFWGLSAFLTLPRLEDPELTPRFALV
                     TTPWPGASAERVESLVSEQIETELQEIEEIDRIDSTSSLGLSVVLLELSDAVDNVDPIW
                     ARVRSKVEDTIPALPADTLRPEFEEIALKASTLIVALKWDLESAPNYTILTRVVQGLED
                     RLRSIPGTDKIETFGEPQEEILVAINQAKLANLGLTASELSRQLQARDAKVSAGTFRGK
                     QDEFLVEVDTQLDTLARIKTTPIQLGSDGQATQLQDIAKITKGIQDPLDSLTLINGKPG
                     ITLSVTMESQERVDQWAQLAHQQIRDFQANLSDGMSVQIIQDQSQYVQQRLNGVIRNLL
                     ASSLLVIGISIVMLGWRAALIVGTAIPLVTLMVFGWMKSLGIPLHQMSITGLIIALGLL
                     IDNAIIVVDEVQHRLQDGLKPAIAMKQTGQHLGVPLLASTLTTVFAFLPIAAARGATGE
                     FIGTIGLTVILALLSSLAVSLTIIASLTAIIGVGKGPSKLPRWAIQGISSPMLSRRFRR
                     LLRLTLAKPVLGIVLALLLPVLGFSQFLSLPQQFFPPTNRDQIQIQVEMPTSSSITQTS
                     ATVRELREVMIAHPEVMDVQWFVGESAPVFFYNVFGQRQNAPNFAQGIVQLASTNTLPK
                     TIQALQQELDTTFPQAQILVQQLEQGPPFGAPIEIEVFGPDVTILRNLGDQLRTLLVQE
                     PEITQTRAILTETLPKLALTVDEVQARRVGLDNEAIARQLNANLEGNTGGSLLEATEDI
                     PVRVRIADADRSDLSAVTSLELLGTQAGQPTQVPLSAIAQVNLVPNLATITRRDGQRFN
                     TVEGYLQAGTLPDKVLKQFQIRLEQSDFQLPPGYSLSYGGEVDARGNAVGNLLSTVGLL
                     VILMTATLVLSFNSFLLAGLIALVALLSIGLGAFALWTFQSIFGFTAILGMLGLIGLAI
                     NDSIVVLAALREDELACQGSRRAIERVVVSSARHVVATTLTTIVGLVPLLFDATGFWPP
                     LAITIAGGLLGATTLALYFVPCMFILIHPKLPWILAMQSSPLADEIKKADITVL"
     CDS             complement(8406..8558)
                     /locus_tag="ctg261_4"
                     /transl_table=11
                     /translation="MSTQEQTFGFTSFAETLSGRLAMVGFSLALVTEVLTGQGIVGQLT
                     ALFSF"
     CDS             complement(8979..9872)
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 115.4; E-value: 5.5e-35)"
                     /gene_kind="transport"
                     /locus_tag="ctg261_5"
                     /transl_table=11
                     /translation="KLSERELGPFATIFNRFWVAYIVLRVWHEWESWRWPLAKLFPQRQ
                     AGLGPSHSAEDDAPESTPQTRRDQLWLVAAALMFWGCIALWAWSLTRTEVANSTLLHNL
                     TPLFTTLGGWLFLNQRFDRQFLLGLMVAIIGAGALGFGDLQLSTAHLTGDIASLLSAVF
                     SAANLMIIEKLRPKFSVNTILQWCCFWGAIWTLPVVLLTEERLFPISASGWGSVICLAV
                     VCQVLGQGLQAFSLKRLSSGLVGILLLLDPVLAALTAWVLFAESLTLFKWSAFFVVLLG
                     VYLAKSSETATQEEPC"
ORIGIN
        1 agaaaagcgt tgaggtcgcg atcgcatcct gccttggact ctagaggtaa acactcagga
       61 cccgttgctt gaatcgtagc gtttgctagg ccagacagaa ctcgtcccgc tcccacttcc
      121 accagcagat cgcactgagg tgccatggct tgcaccaggg ccacaaaatc aatcgacgag
      181 gtgacttgat ccgcaaagtg attgcgtaga ttcagtcctg actgcacctg tgctccattc
      241 atactagaga acagcgctaa agataagttc tccaacacat cgggtagagg cgcatccgtt
      301 ctgagttggt ctgcagcccc agcgacaaag gaggagtgga aagcattaga gacgggcagc
      361 tgtcgcacct gaatcccttg gctgatagct aactgcatca cagaggctat gccggatgat
      421 gtacctgaaa tcacggtttg ttcaggacta ttaatattgg cgatggcaac gtcatcttct
      481 atgcaggcta agagagattg agcgatgtca gcagaacaac cgaggctagc cattgccccc
      541 cccgttcgtc ctgctgacat cgcctgcccc cgcaccgccg ccagatgtag taaggtttcg
      601 acatcgaagg ccccggctcg atgaaaagcc gtcagctctc ctaaactatg cccacccact
      661 gctactggct gaattccgag tcggtccaag tagccactcc agagcaacga ggtgagacac
      721 agggcaggct gagcaacatg ggtttgtgct agctcctgag tccaggtttg gatttctgct
      781 ggattagccg cttgttcaac gggtcgataa atcaagggac tcacagactg agcccccatc
      841 ttttgcagtt gggtatcgag ctgggtcact agatctcgcg cccaaccata acgttccacc
      901 aacgtccgag ccatatttaa ccgctgtgat ccctgtccag ggaacaaaaa accaactcgg
      961 tcttgctgga gcgcgttagc aacccaaaat ccttgaggcg gaaccgatgc catttctcca
     1021 ggaccaatag gatgatctac cagatattgt tcaagctgtt gtagttgctc aatgagggct
     1081 tctggggatc gggcaaccac agcagccctt agagcatgcg tagggtgcaa aaatgtagtg
     1141 agatggactg caagatccgc tagctctgca tcactgatgc cagtcgcggc ttggcgaatc
     1201 gctgctattc tggctaataa acctgaaatg gaatcaccac tgagaacaat cagctccgtt
     1261 tcttgaggtg aaactaacag tgctcgttcg tccacagtag gctttagatg agcggcagga
     1321 gcatccgctg atgctagcgt aatatgtgaa ttgatgccgc caaatcccat agcagacacg
     1381 ccagcccgca gctgactagt ggaggatcga actgctcccg tgagcactgg atacactcct
     1441 agcgctagag actcaaaaac agcactgggg ttttggcaac ctgctgtagg cggaatgatg
     1501 cgttgattaa cggccatcac tgccttgatc aaaccgccaa tccccgccgc cgctttggta
     1561 tggcccatga tcgacttgaa tgacgtcacc cccacagacc gaggggtgac gtctccattg
     1621 gcatgaacaa cggctgcaat gccttctaac tcagcgcgat cgccaacagc tgtccctgtc
     1681 ccatgtcctt caataaagtc gacctcgcag ggacggtaac ctgcctggtc ataggcccgt
     1741 tgtagtgctt tagcctgacc ctgaccagaa ggcgcggtaa tcccaccttt gccatccgac
     1801 gaaatgcccc aaccctgcaa cgttgcatat atgtagtcgc cgtcagcccg agcatcagct
     1861 aagcgtttca ggaccacaaa accacaccct tctcctggca aaaacccatt agctgcctgg
     1921 tcataaacag ccatatcgcc tgcggttaat gccccagttt tggcaaaacc aatcagttca
     1981 aaggggtcca agctaacatc aaccccccct gccagagcac aatccaactc acctgccgcc
     2041 agagccgttg ctgctgtctt caccgcaata agtgaagagg cacaggctcc atcgacgata
     2101 tatcctccac catcaagatt gaatgcattg cagatacgtc ctgcaattgt attggcaagg
     2161 ccacccgcca aggagtcttc agtaattgat gcaaagggag acttatagat ggcttccagc
     2221 gtctccatca aggcttgagc agccgctgtt gagattccgt gaacagtagc ggctgcttga
     2281 acggcgcgtc gtacgtaagg ccaacgcaac cgcagggtgc tggcgcgagt ttgttcacct
     2341 gtaagcgtat taccaacaat gacacccatt gtttgagttg aaacattgtg gctcttcatc
     2401 aacatactgg ctgacgaaaa atcttccgca cgaccagcgc aagatgcagc atctttcagc
     2461 gcctgatagg cagtatccaa tgccaaccaa tgcacaatat ctgttctgtc aaaagtcgtt
     2521 ttgggaattc gccaagctgc ccaatcaaat tcgaagccat caatcaatgc tgcttgtttg
     2581 ccataggtct ggtctggcga ttttggatcc gaagcataat attcagatag tggtatccgt
     2641 ctctcaggaa gggttctaaa ctgacggcgt cttcctaata tgttctccca cagagtcttt
     2701 aaattttttg cgccgggata gcaacagccc atgccaatta cagctatttt ggcagcagaa
     2761 gaaatatcta ctgagatggc gttagatttc attgaggttt aatagctcaa atcaaagctt
     2821 ataggtaaat agttatcttg cacagagtaa cagagtcaca acaaaacaat tgtaaaaaaa
     2881 ctgtaaagcg aagaaaaact agattctttt agactcagat atattttaga gtactcagtt
     2941 atttactgca tagctttatt tttttacatg catagaaaat tcttacttca aagttcttca
     3001 atttctctaa tagatagata tcagagcaat cgcaaaactc atcattagtg ttttttgtag
     3061 atttttaatt agctctaatt taatatgctt ttaccttata ttccatatct agcagctata
     3121 gaatccttaa ttccgtgcaa tatttgacat tgctcaactt tgaattctat tttgtagcta
     3181 tagctatttt attcagattt gtagttagaa tcacttacta atcttgttca agagtgcatt
     3241 cgcagccttt agttgagaca aaaatacttt acatggtaac aatagtctta ataatttgag
     3301 ttactgtata tctacaatcc ataacaataa gaaaaatcag catcgcgtga ctcaccagtt
     3361 ataaaactaa tagtctttga gccacagaca cagccaaaca tgagtaaggt gagagcacag
     3421 taggatataa aagtgtctgc acaaacaatc cggatatttt atattctttg gactggtcag
     3481 tgctgtggtc tttcttgctt tttgatgttg atgtgacttg caacatttct agtactactt
     3541 ggcaccaatc tatttactct tgctcgtgtc aaattcttcg tctgagcctc agagatcgaa
     3601 actgcatcat ttattgaggt catactcgca ataagacccc tcaaataaag ctgtcaaatc
     3661 ccgtgtacaa aagacatagc aggttgatgt actggcattg acagctccaa caaggcgagc
     3721 ataagctatc gattaatact cggcaggttt tgtatcaaca agttggatat taagcatgga
     3781 tcaacaatcc cctgcaatac cagaagcccc tacaccttcc tcttccgtga agccaatccg
     3841 ctggaaatcg ccgcgttgtt tggggcttgc acttatgtgc ataggagtgg cagtaggggt
     3901 caaaacttgg ggagttaccc aggagactgc agccccacgc gctctattac ctgtctcgac
     3961 cttgtccctg cagccttcat cgttctataa cattcaacgc agctattcag gtgaagtcca
     4021 agcgcatcgc actagtgagc tgggattcga actgacagga acattgattg atattgctgt
     4081 agaagagggc gattgggtca atcaagggac tctcctagcc cgactagata cgcggatgtt
     4141 agagacgcag cggcaacagc ttcttgccca aaaagctcag gcccaagccc agttccgaga
     4201 actcaaaacg ggtccgagaa cggaagaaat tggcgccgcc cgagctgccg ttgaggattt
     4261 gggacagcag cttttgttag cccagaagca aagccaacga cggcaaaact tgtacaaaaa
     4321 aggggccatc tcacgggagt cctttgaaga acggtacttt gccgctgccg ctttaaaaaa
     4381 acggcaaggt caagctcaaa aacgcttgga agagctatta gcaggaaccc gagtggaaaa
     4441 agtcgagttc caggcagccc agttagcaga gattgacgcg caacttgatg ccctgaaaat
     4501 tcagcgatca aaaagcgtgt tacaggctcc tttttctgga caggtggcgc agcgtctaag
     4561 ggacgaaggt gttgttctga atagtggtca gccgatccta cgaatcgtgg aagccgctcg
     4621 ggtagaagcc cgcattggcg taccccaaac aatggctaag gaaatgaggc ccggtcaaac
     4681 ctaccctctt cacatcggca accaacgcta tgtgggtcag gtgcaaacac tactgccgga
     4741 agtagaccct cagagtcgca ctgtgactgt catattagcg attacaggag aagctgcttt
     4801 gccgcttggc caaacagcca aaatcacctt ggcccaacgc caaaatcaag ctggattttg
     4861 gctaccctcg actgccatca ttaccgggga aagaggatta tggtcagcct atgtgctgaa
     4921 accatcagca caagacgcag tttttagcgt ggctcggaga gctgttgaag tcctgcatac
     4981 ggagggcgat cgcagctatg ttcgtggcat gttgaagccg caagagcagg tcattattac
     5041 tggcacacgt cgtattgctc cgggtcaatt agtccgagtt gccaactctc aataacagcg
     5101 ccatactcca acgatacgag acgcgtatca ccatgttcaa cttgttttat cggaatcgac
     5161 agttactaag cctatcgatt accctgatcg tcttctgggg actgtcggcc tttctgactc
     5221 tgccccgctt agaagacccc gaactgactc ctcggtttgc tctcgtcacc actccgtggc
     5281 ccggtgctag cgccgaacgg gtagagtctt tagtctcaga gcaaattgag acagaactcc
     5341 aagaaattga agaaattgat cggatcgatt ctacgtccag cttgggccta tcggtggtgc
     5401 tgcttgaact gagtgatgct gtagataatg tcgatcccat ctgggcacga gtacgtagca
     5461 aagtcgaaga tacaatccca gcgctacccg cggatacgtt gagacctgag tttgaagaaa
     5521 ttgctctcaa agcctcaacg ctgattgtgg ctttgaaatg ggacttagag agtgctccaa
     5581 attacacaat tttgacacgg gtcgttcagg gactagaaga tcgactgcgc agcattccgg
     5641 ggacagacaa aattgagaca tttggtgagc cccaagaaga aattctagtc gcaatcaatc
     5701 aggccaagct agcgaatttg ggattgactg cctccgaact ctctcggcag ttgcaagcca
     5761 gggatgctaa ggtttctgcc ggaaccttta gaggcaaaca agatgagttc ttagtagaag
     5821 tagacaccca acttgatact ctagctcgga taaaaaccac acccattcag ttagggagtg
     5881 atggacaggc aacccagctt caggatatcg ccaagatcac caaaggtatc caagaccccc
     5941 tagatagcct cacactcatt aatggtaaac cggggattac cctgtcagtc accatggaat
     6001 cgcaagaacg cgttgatcaa tgggctcaac tggcccacca gcagatccgg gattttcaag
     6061 ccaacctatc agacggcatg agtgtacaga tcattcaaga tcagagtcag tatgttcaac
     6121 aaaggctgaa tggcgtcatt cgcaatttgc tcgctagttc tttgttagta atcggcattt
     6181 ctatagtgat gctggggtgg cgagcagcct tgatcgtagg cacagctatc ccattggtga
     6241 cgctgatggt gtttgggtgg atgaaaagtc taggcattcc cctccaccaa atgtctatta
     6301 cgggtctgat tatcgcctta gggttattga tcgataacgc cattattgtt gtggatgaag
     6361 tccaacaccg gttgcaagat ggattgaaac ctgcgatcgc gatgaaacaa accgggcaac
     6421 atttaggcgt tcccctgctg gcatcaacct taacaacggt ctttgccttt ttgcccattg
     6481 cggccgccag aggagcaact ggggaattta ttggcaccat tggcttaacc gtaatcttgg
     6541 ctttgttgag ttccctcgcg gtctcattga ctatcattgc ctccctaacc gccatcattg
     6601 gtgtgggaaa gggaccctct aaattgccgc gttgggctat tcaggggata tccagtccga
     6661 tgttatctag gagatttcga cgcttactcc ggttaacgtt ggctaagcct gttctgggga
     6721 tagtcctggc tctgctccta cccgttttgg gttttagtca atttttgtcc ctacctcagc
     6781 aatttttccc gccgaccaat cgcgatcaaa ttcaaattca agtggaaatg cccacttcca
     6841 gctccattac ccaaacatca gccacggtca gagaactgcg cgaggttatg attgctcatc
     6901 ccgaagtgat ggatgtgcag tggtttgtgg gcgaaagcgc ccctgtgttt ttttacaacg
     6961 tctttggtca acgccaaaat gccccaaatt ttgcccaagg tattgttcag ttggcctcta
     7021 cgaacacctt gcctaaaaca atccaagcgt tgcaacaaga gttagataca acctttccgc
     7081 aagctcaaat cttggttcaa cagctagaac aaggccctcc ctttggtgcc cccattgaaa
     7141 tagaagtgtt tggaccagat gtgactatct taagaaattt gggtgatcag ctccgcaccc
     7201 tactcgttca agaaccggag attacccaaa cgcgggcaat cttaacagaa actctcccca
     7261 aactcgccct cacggtggac gaagttcaag cccgacgggt gggtttggat aacgaagcca
     7321 ttgctcgaca actcaatgcc aatctggaag ggaatacagg cgggtcacta ttagaagcga
     7381 ccgaagatat tccagtccgg gtgaggattg ccgatgccga tcgctccgat ttatctgcgg
     7441 tgacctccct ggagctgctg ggcactcaag ccggtcaacc cactcaggtg cctttaagtg
     7501 cgatcgccca agtcaatcta gttccaaatc tagcgaccat tacccgccgt gatggtcaac
     7561 gcttcaatac agtggagggt tatttgcaag caggaacttt gccagataaa gtactgaagc
     7621 aattccagat ccgactagag cagagtgatt ttcaactgcc accaggatat tctctatcct
     7681 atggcggtga agtagatgca cggggcaatg ctgtcggtaa tttattatct actgtcggtt
     7741 tattagtgat cttaatgacg gccaccctgg tgctctcgtt taattcattt ctattagcag
     7801 ggttgatcgc tctcgttgcc ttattaagca tcggcttagg ggcttttgct ctgtggactt
     7861 ttcaatctat ttttggcttt acagccattc tggggatgtt gggcttaatt ggcttagcta
     7921 tcaatgattc catcgttgtg ttagctgcat tacgcgaaga tgagctggcc tgtcagggat
     7981 cgcggcgggc gattgagcgg gtggtggtgt catcggctcg gcatgtggta gcgacgacat
     8041 taacaaccat tgtgggtttg gtacctttac tatttgatgc aactggattt tggccaccct
     8101 tggcgattac cattgctgga ggcttactag gggcaacgac tctagcgttg tattttgtac
     8161 cctgtatgtt catactcatt caccccaaat taccttggat tttagccatg caatcttcac
     8221 ctttggcaga tgaaatcaag aaagcggata taacggtcct gtagtgaaac tgttgccagg
     8281 gtctaatacc tactactccc aaaatacatt tgatcgttag tgctcatgaa aaaggcccca
     8341 gctaagctag ggccaagaag cgcgaactat tactcaaaac aatacggctt aaaccgtaac
     8401 gggatttaga agctaaataa agctgtaagc tgacctacaa ttccttggcc agttagaact
     8461 tcagtaacta gggctaaaga aaagcccacc attgctaggc gaccactgag ggtctcagca
     8521 aagctagtga atccaaatgt ttgctcttgt gtactcatgg tgtttgactc cgtaattgtt
     8581 gggcatgtgc tgcatggata cgagtgtaac gaaaatataa ataaataaca atgtttattt
     8641 gacaatgttg atcatttaca ttttctatgt atccattgct acgaaatcaa gatagagatt
     8701 gcccaaaagc actgtcatta gtttcttacg ggcacaagat tttggactta ctgctggggt
     8761 tctcccaaga ttaattgggc gagaatccct atatcaagac cctcaattca acctattgga
     8821 gtatttttcg agatgtttgt aaagcttagg ttcataaata ggtctttatt ctctctggca
     8881 tgactgtaac cgtcgccaac acaacacata ggtctataga ccaacatcgg cctacctata
     8941 cctatatatt tcacatccaa cagataacag atagataatt agcagggctc ttcctgagtc
     9001 gctgtctcac tagattttgc taggtaaacc cccagtaaca ccacaaaaaa ggctgaccac
     9061 ttaaacaagg tcaaactctc tgcaaacagg acccaagcgg ttaacgctgc taaaaccgga
     9121 tctagcagaa gtaagatgcc aactaatccc gacgataagc gtttgaggct aaaagcttgc
     9181 aagccctgac ctaatacttg gcagaccact gccaaacaaa tcactgatcc ccaacctgat
     9241 gcagagatag gaaacaagcg ctcttctgtg agcaagacaa ctggtaaagt ccagattgcc
     9301 ccccaaaaac agcaccactg caagatcgta ttaacggaga atttgggcct tagcttctca
     9361 ataatcatta agttagcagc ggaaaagaca gccgataaca gggatgcaat atctccggtg
     9421 aggtgagcag tcgaaagctg caaatctcca aaccctagag caccagcccc gataatcgct
     9481 accatcaatc ccagcaagaa ctggcgatcg aaccgttggt taagaaacag ccatcctccc
     9541 aaagttgtaa acagaggagt gagattatgc agcaacgtcg agtttgccac ttcagtacga
     9601 gtgagagacc aagcccaaag agcaatacat ccccaaaaca tcagggcagc agccaccaac
     9661 cagagctgat cgcgccgggt ctgtggggtc gattccggtg cgtcgtcttc agcagaatga
     9721 gagggtccaa gaccagcctg ccgctgagga aagagcttcg ctaacggcca gcgccaactt
     9781 tcccattcat gccaaactcg gagaacaata tacgccaccc agaaacgatt aaagatcgtg
     9841 gcaaagggtc ctagttcccg ctcgctcagt ttg
//
