LOCUS       c00328_3300027..       14385 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027370.a:Ga0209010_1000392.
ACCESSION   c00328_3300027..
VERSION     c00328_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 12:35:18
            Original ID  :: 3300027370.a:Ga0209010_1000392
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14385
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14385
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:1799](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..1799)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..14385
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14385
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     aSDomain        complement(3..149)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg328_1_PP-binding.1"
                     /evalue="1.10E-07"
                     /label="ctg328_1_PP-binding.1"
                     /locus_tag="ctg328_1"
                     /protein_end="599"
                     /protein_start="550"
                     /score="24.0"
                     /tool="antismash"
                     /translation="ALAELVASVTGHPMRAMAKESNLETDLGLSSLDRVELLSVIEERY
                     QVDL"
     aSModule        3..1700
                     /complete
                     /domains="nrpspksdomains_ctg328_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg328_1_PP-binding.1"
                     /locus_tags="ctg328_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS             complement(3..1799)
                     /NRPS_PKS="Domain: AMP-binding (33-440). E-value: 8.2e-80.
                     Score: 260.1. Matches aSDomain:
                     nrpspksdomains_ctg328_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (550-599). E-value: 1.1e-07.
                     Score: 24.0. Matches aSDomain:
                     nrpspksdomains_ctg328_1_PP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     252.1; E-value: 1.4e-76)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg328_1"
                     /sec_met_domain="AMP-binding (E-value: 3.1e-78, bitscore:
                     253.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.6e-08, bitscore:
                     24.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSESLSTSLAEFLLPHFEAHLRERAYGQRRGYRMEWFTYGQVRDL
                     CFRFVRELEARQIRKGDRVMLWGENCAEWVAAFWGCVIAGVVVVPMDDGAAADFAGRVL
                     LQVGARLVVCSRGHMPEIAKTSPFLILEELAVTLSSLSDDAVPVSYVGRHDFLQIVFTS
                     GTTAEPKGVVITHGNVLTNVAPLAQQIRGYLKYERLVHPVRFLNLLPLSHVFGQFLGMF
                     LPPLMGATVIFQDEFKPAEIVSTARREKVSVVVSVPRLLQSLRQKLERDFEDRGELEMF
                     RRRFSAAQRKHFFWRWWIFRDIHRQFGWKFWAFISGGAALDSEAEEFWGRLGYAVIQGY
                     GLTETTSLISVNHPFRLGKGSIGKVLPGREVKLAADGEILVRGGGVASAYWQAEASRNG
                     DYKLADAVADGDGWYRTGDLGALDEAGNLYFKGRKKDVIVTPAGLNIYPDDLEVTLRRQ
                     PEVRDCVVVGIERGGNAEPCAVVILRDGSLEAVVRRANESLAEYQQIRHWAQWPDDDFP
                     RTSTQKPRKQLILQFAQKQIFGSSSTSQPEAKSALAELVASVTGHPMRAMAKESNLETD
                     LGLSSLDRVELLSVIEERYQVDL"
     CDS_motif       complement(159..191)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg328_1_0002"
                     /evalue="2.20E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg328_1"
                     /protein_end="547"
                     /protein_start="536"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="IFGSSSTSQPEA"
     aSDomain        complement(480..1700)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg328_1_AMP-binding.1"
                     /evalue="8.20E-80"
                     /label="ctg328_1_AMP-binding.1"
                     /locus_tag="ctg328_1"
                     /protein_end="440"
                     /protein_start="33"
                     /score="260.1"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="MEWFTYGQVRDLCFRFVRELEARQIRKGDRVMLWGENCAEWVAAF
                     WGCVIAGVVVVPMDDGAAADFAGRVLLQVGARLVVCSRGHMPEIAKTSPFLILEELAVT
                     LSSLSDDAVPVSYVGRHDFLQIVFTSGTTAEPKGVVITHGNVLTNVAPLAQQIRGYLKY
                     ERLVHPVRFLNLLPLSHVFGQFLGMFLPPLMGATVIFQDEFKPAEIVSTARREKVSVVV
                     SVPRLLQSLRQKLERDFEDRGELEMFRRRFSAAQRKHFFWRWWIFRDIHRQFGWKFWAF
                     ISGGAALDSEAEEFWGRLGYAVIQGYGLTETTSLISVNHPFRLGKGSIGKVLPGREVKL
                     AADGEILVRGGGVASAYWQAEASRNGDYKLADAVADGDGWYRTGDLGALDEAGNLYFKG
                     RKKDVIVTP"
     CDS_motif       complement(1272..1325)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg328_1_0001"
                     /evalue="1.60E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg328_1"
                     /protein_end="176"
                     /protein_start="158"
                     /score="23.7"
                     /tool="antismash"
                     /translation="IVFTSGTTAEPKGVVITHG"
     CDS             complement(1904..2158)
                     /locus_tag="ctg328_2"
                     /transl_table=11
                     /translation="VTLDKGLVEALEKDYTTAPITPQERVMLDYVVKLTRDATKVWKDD
                     IEGLRAAGFDDRGILQITLIASWFNYINRVADALGVGRE"
     CDS             complement(2189..2470)
                     /locus_tag="ctg328_3"
                     /transl_table=11
                     /translation="MTWIKTIPLTEADEKLRQAIEGEKSFYPREYADPVHPDASGASSI
                     VGSHTLIPQALYHAFSTFGALMAPDLPLQRRQHEMIATVVSVTNSCQY"
     CDS             complement(2581..2961)
                     /locus_tag="ctg328_4"
                     /transl_table=11
                     /translation="VGRALVRKKAGKVETANRRERRGAERVMELPELDRLIHERIRLGI
                     VSALATNESLSFNDLKRILKTTDGNLSVHARKLEEAQYIACTKFFEGRVPRTEYRLTTS
                     GRRALAQYLDQMEEWIRVTREE"
     CDS             complement(2954..3574)
                     /locus_tag="ctg328_5"
                     /transl_table=11
                     /translation="MQEHQTHRQRFRRRPVRPIPSRAAEDLRYIRDTMERSASFTAVSG
                     WGQVLLGVTALAAAVVAGGQPAGFTWLRVWLAEALVAVAIALLSVVWKANRRGLPIFSG
                     PGRKVALGLLPPLLAGAFLTFLLYRMGAQSALPATWLLLYGAGIATGGAFSVAIVPVMG
                     MCFMTLGGLAVVGPAAWGNWLLAAGFGGLHIVFGIMIARRHGG"
     CDS             complement(3650..5797)
                     /locus_tag="ctg328_6"
                     /transl_table=11
                     /translation="MNSFIPRVVELIFLMATATVPFGVAQQNWPSYGGSPENNHYSSLA
                     QINRTNVRKLAVAWKFDTQEVGGLQTTPIVVDGVLYGITPTEKIFALDAATGKLLWRFD
                     SGILGTQPDRGLAYWPGDGDSGVNKEVKKKDGRILVGVMNFLYALDAATGKPIPSFGDQ
                     GRIDLRDNLGREPASAQSVYLTSPGAIYKDLVIVGGRNPETLPAPPGDVRAFDVRTGKM
                     RWAFHTIPHPGEFGYDTWPKDAWKTSGAANNWAGFALDAKRGIVYVPTGSAAFDFYGGD
                     RIGDDLFANCLLALNAETGERIWHFQGVRHDIWDRDFPASPALLTLNRDGHSVDAVAQT
                     TKQGFVYLFNRANGNPLFPIEERKYPASTVPGEKAASEQPLPMKPAPFARQLLTEVMLT
                     TRTPEAHQWALEQFRTFRSEGQFVPLSIGKDTVIFPGFDGGAEWGGPAVDSETGVIYVN
                     ANDIAWTGTLAENAGDNSAKAIYMSQCSVCHGERMTGSPPAFPSLVGVETRLTRAQITA
                     TIRNGKGRMPGFPNLADDQTSVLVGYLTSGENKELGGSAQISGNAPYRFTGYKRFLDSG
                     GYPAVAPPWGTLNAINLNTGEYLWKIPLGEYPELTAQGQKKTGTENYGGPIVTAGGLVF
                     IGATNFDKKFRAFDKTTGELLWETSLPFAGNATPATYEVDGRQFVAIAAGGGKDPKSGS
                     GGVYVAFTLPQDPSTKQANPK"
     CDS             6234..7517
                     /locus_tag="ctg328_7"
                     /transl_table=11
                     /translation="MAYELRCRECGRSWGNQPRSICHDCFSPLEVAYDYDAARASISLK
                     EIAQRPPNMWRYSELLPLPARFEPRLPVGFTPLLQAPRLGAKLGGKFAAKNVYIKNDAV
                     CLPTLSFKDRVVAVALAQACEFGFDTVSCSSTGNLANAVAAHAARLGLKAWVFIPADLE
                     PAKILGTNVFGATVVRVNGSYDQVNRLCSQIAEEHPWGFVNVNLRPYYSEGSKTVGFEI
                     AEQLGWRLPDNVVCPMAGGSLIIKIKKAFDELVKVGLVEAKEVKFFGAQATGCSPISTA
                     VKTASSEIEPQKPATIARSLAIGNPADGLYAIKTIKQSGGWSEDVSDPEVVDSIRLLAE
                     TEGVFTETAGGVTVGVAGKLYRQDRILPEETTVLCITGNGLKTTDALNGVFEAETPIAP
                     KLAEFENYLQRTLDTSDADKQFAVAAGV"
     CDS             complement(7537..8598)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 168.2; E-value:
                     6.7e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg328_8"
                     /transl_table=11
                     /translation="VISIKKYLDISSGQVEQTASEPSPLVTALMQAYRSTIASVGENGA
                     RAIPAVASDLLTALARLQSGLEEVPSFSLVQETEKSVAEQLDVWGMRAAEYCKSKTGEV
                     KELLIALARTAESMGQRDLRYSGQMLELTRQLEAIADLEDLGQVRASLVRKATELKGCV
                     DQMAEENRRAITALKAEVSTYETRLREAETVASKDSLTGLFNRRSMEQRIELAITEQRP
                     FCVVVLDLDGFKQVNDTHGHTVGDALLVQFSEEVRTNIRSTDIAGRWGGDEFVLLLTCD
                     RTSARAQIERIEKWVFGEYTLPATGRKEPLKLQVRASVGVAEWNRGETLAKLIERADHV
                     MYREKKLARKQHE"
     CDS             complement(8846..9040)
                     /locus_tag="ctg328_9"
                     /transl_table=11
                     /translation="MAGRTSFNKRQKERSRQDKQREKTEKKVQRRLEKPTDPKDLDSLV
                     DFSAFQSQMALPGETSGDE"
     CDS             complement(9134..9562)
                     /locus_tag="ctg328_10"
                     /transl_table=11
                     /translation="MKKLFVGNIPHSTTEAELRNLFEPHGAIAQVSIVTERETGRSRGF
                     AFVEMNDAAEAEKAIAALNGKELGGRALNINEARPKTEGGGGGFRGARPGGGGRPGGGG
                     RPGGGGGRSGGGGGRSSGGGGGRDDYQGHARQPREPRW"
     CDS             complement(9627..9809)
                     /locus_tag="ctg328_11"
                     /transl_table=11
                     /translation="MSSINGDKSRFNRVRKQRIFQRQRNRILVHGLITAGGQTPHAAAK
                     APLSTPPASKTDIQP"
     CDS             complement(10015..10536)
                     /locus_tag="ctg328_12"
                     /transl_table=11
                     /translation="MDKAVTDIRSLQKPLKEQYRRDPASSRITLTAKGSETATPLSCSV
                     DIGRAIYQAEAHKGVGGAGTAACSGDLLLGALAACAQLTCQLVATAMGIQTRQIEVTVD
                     GDMDLSGTLGISKEVPVGFDAIRVRFNVDAPEATPEQLRLLGEKTEQYCVVLQTLLRPP
                     KIQAQWNGAR"
     CDS             complement(10597..11571)
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 97.8; E-value: 1.1e-29)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg328_13"
                     /transl_table=11
                     /translation="MKEITILLLDQMFSSTAIGPMEVFRHAGSLWNILTGSTLAPSFHV
                     ITASADGRPVNCDGEIQIRPNVALKDVGKTDLIFVPTTGLSVDDVVERNAAIVPWLKRR
                     SAKDVSIASVCSGVGLVAAAGLLDGKRATTHWGLAERFREKYPKVKWMPELMVTEDHGF
                     YCGGGVNASLDLSIYLVERFCGHEIAVQTAKALLIETPRAWQSGFAIVPLKTDHTDDSI
                     SSAQEWMHGNFAKTFSLEEPARRVGMSVRNFVRRFKQATGDSPLIYLQKLRVAAAKRML
                     ESNHRSMQEISDAVGYQDVAFFRSLFQRHTGVAPSAYRERFGT"
     CDS             11738..12310
                     /locus_tag="ctg328_14"
                     /transl_table=11
                     /translation="MATAQKLPKIVNGVNVTDLFATIDAIKATPAIAKFKFRIHNQWNG
                     ASQNRSTVNKFHGADQELSRAKPFVLEADEPAVLLGKDTAANPVEHLLHALASCLTTSM
                     VYHAAARGIRIEEVESQFEGDLDLHGFLDLDKNVRNGYQGVRVNFKIKADVADEQLQEI
                     VELGTGHSPVFDCLTNGVPVSVNAERL"
     CDS             12467..13042
                     /locus_tag="ctg328_15"
                     /transl_table=11
                     /translation="MTRITKLIHVSTKAILPLALLSGLITASPVFAQQPAEHSMHSAAP
                     VPAQLVQDVRAATKQFINVNNAGPAGYGPAFGCVSGPDHGAMGIHYVNGALVTDGLIDV
                     THPEALIYEPVGNARRLVGVEYIVDAATWLANNNGIPPQLDGQDFQFIAAPNRFALNDF
                     FELHVWAWRDNPQGAFVDWNNQVSCEGE"
     CDS             14036..14383
                     /locus_tag="ctg328_16"
                     /transl_table=11
                     /translation="MRINKATNFRKTFFCKVFFWTICVCTIMTTCLLASLPAFAQTCAS
                     GDCQPGLITGPYSAAEAAQNTAVNFPVCTSAACQASTWENNQIEGIDAQQNIGTPYQFY
                     DNALNLDTNIAV"
ORIGIN
        1 ccaagatcaa cctgatagcg ctcttcgatt acgctcaaca actccacgcg atcgagagaa
       61 ctcaatccca gatcggtttc cagattggat tccttggcca ttgctctcat agggtgaccc
      121 gtgacgcttg cgactaattc agcaagagcg ctttttgctt cgggctgaga tgttgacgac
      181 gaaccgaaaa tttgtttctg cgcgaattgc agtatgagtt gcttgcgtgg cttttgcgta
      241 ctggtgcgcg ggaaatcatc gtccggccac tgcgcccagt gccgtatctg ctgatactcg
      301 gccaatgatt cgttggcgcg tcgcaccaca gcctcaaggc tgccgtcgcg caaaatcacc
      361 actgcgcagg gctccgcatt gccgccgcgt tctatcccca ccactacgca atcccgaacc
      421 tccggctggc gccgcagcgt aacttccaga tcgtctggat aaatattcag ccccgcgggg
      481 gtcacgatca catccttctt acgccccttg aaataaagat ttcccgcctc atccagcgcg
      541 cccagatctc cggtgcgata ccatccgtcg ccgtccgcaa ccgcgtcagc aagcttgtag
      601 tcgccgttcc tgctcgcctc cgcttgccaa tacgcagaag ccacgccgcc tccccgcacc
      661 aggatttcgc cgtccgcagc aagtttcacc tcgcgccccg gcagcacttt cccgatcgat
      721 ccttttccca agcgaaacgg atgattcacg ctgatgagcg acgtcgtctc cgtgagcccg
      781 tatccttgaa tgaccgcata acccagacgc ccccaaaatt cctccgcctc gctatcgaga
      841 gccgcacctc ccgaaatgaa cgcccagaat ttccatccga actgacgatg aatatcgcga
      901 aaaatccacc atcgccagaa aaagtgtttc ctttgcgccg ccgaaaaacg ccgccggaac
      961 atctccagtt cgccccgatc ttcgaaatca cgctccagct tctgcctcag cgattgcagc
     1021 aatcgcggca cgctcaccac caccgacact ttttcccggc gagccgtgct cacaatctcc
     1081 gcaggcttga attcatcctg aaagatgacc gtagcgccca tcagcggggg caggaacatt
     1141 cccagaaatt gcccgaagac gtggctcaga ggcagaagat tcagaaagcg cactggatgc
     1201 acgaggcgct catacttcaa atagccgcga atctgttgcg ccagcggagc tacattcgtc
     1261 agcacattcc cgtgcgtgat aaccacgccc ttcggttccg cagtagtgcc cgaagtgaaa
     1321 acgatctgca agaagtcatg gcggcccacg tagctgaccg gtactgcatc gtcggagagc
     1381 gaactcaaag tcaccgccaa ttcttcgaga atcaggaacg gcgaagtctt tgcgatctcc
     1441 ggcatatgtc cgcgcgagca gaccacaagc cttgccccca cctgaaggag tacgcgcccg
     1501 gcgaaatccg ccgccgcgcc atcatccata ggcaccacaa ccacaccggc aatcacgcat
     1561 ccccaaaaag cggcaaccca ctccgcacaa ttctcccccc acagcatcac gcggtcaccc
     1621 ttgcggattt gccgcgcctc cagttcgcgg acaaaacgaa aacacaaatc cctcacctgt
     1681 ccgtatgtga accattccat gcgatagccg cgccgctgcc cgtacgcgcg ctcccgcaag
     1741 tgcgcttcaa agtgcggcag taaaaattcg gctagagatg tagataaaga ttcggacatg
     1801 aggagacagg ccaggaaacg agccttggcc ttacctatgc caagtttagt tgcagaaaca
     1861 aggtaagagg aaatccgagc cggaatccca ggctaacgaa gagctactcc ctgcccactc
     1921 ccagcgcatc ggccacacga ttgatgtagt tgaaccacga cgcgatcagc gtgatctgaa
     1981 gaatcccgcg gtcgtcgaat cccgcggcgc gcaagccttc gatatcgtct ttccaaacct
     2041 tggtggcgtc gcgtgtgagc ttgaccacgt aatccagcat cacacgttct tgcggcgtga
     2101 tgggtgcggt ggtgtagtct ttttccagtg cttctacaag gcctttgtcc agggtcacgc
     2161 gacgcagaaa ctctgcgtgg gattcgattc aatactggca gctattggtg accgagacga
     2221 cggtcgcgat catttcatgc tggcgccgct ggagcggaag atcgggcgcc atcagcgcgc
     2281 caaaagtgct gaacgcgtga tacagcgcct gcggaatcag cgtgtgtgag ccgacaatcg
     2341 acgaagctcc agatgcgtcc ggatgcaccg ggtcggcgta ctctctgggg taaaaacttt
     2401 tctcgccttc gatggcttgg cgaagctttt catcggcttc cgtcagagga atggttttga
     2461 tccatgtcat ggttgtgcgt tcctcccgca gaatgctctg caattgttgc agcaggaacg
     2521 atacaccgct gcgccacgca cagcctatag cggatttgta ttagcggctt gggggcagcc
     2581 ttactcttcg cgggtcactc gaatccattc ttccatttga tccagatact gcgcgagcgc
     2641 ccggcgcccg gaagtagtca agcggtattc ggtgcgaggg acgcggccct caaaaaactt
     2701 cgtgcacgcg atgtactgcg cctcttccag cttgcgcgcg tgcacactga gatttccatc
     2761 ggtggtctta aggatccgct tcaagtcgtt gaagctcagc gattcgttag tggccagtgc
     2821 gctcacaatg cccaggcgga tgcgctcatg aatcaagcgg tcgagttccg gcaattccat
     2881 gacccgttcg gccccgcgcc gttcgcggcg gttggcagtt tcaaccttgc ccgccttctt
     2941 ccggaccaaa gccctaccca ccatgtctcc tcgcgatcat gattccaaac acaatatgca
     3001 atccgccgaa tcccgccgcc agcagccagt ttccccacgc cgcggggccg accacggcga
     3061 gccctcccag agtcataaag cacatgccca tcactggaac gatagccacg gaaaacgcgc
     3121 caccggtggc gattcccgct ccatagagca gtagccacgt tgccggcaac gccgattgcg
     3181 cgcccatccg atataacaaa aaggttaaaa acgcgcccgc cagcaatggc ggcaagagcc
     3241 ctaacgcgac ttttctgccc ggaccggaaa aaatcggcag accacgccga ttcgctttcc
     3301 acacaaccga caacaaagca atcgccacag ccaccaaggc ctcggccagc cacacccgca
     3361 gccaggtaaa accggcgggc tgcccccccg cgacaactgc ggcggccagg gctgttacgc
     3421 caagcaaaac ctggccccac ccggaaacgg cggtgaacga cgcagaccgt tccatggtgt
     3481 cgcggatgta acgcaagtct tccgcggcgc gcgagggaat cgggcgcacg ggtcttcgcc
     3541 gaaatctttg ccggtgggtc tggtgttcct gcattcacta aaaagactat gggacgcgaa
     3601 gcagtgtggt caagtacttt gtacagcaaa gaaccagaag gcgattcttc tatttcggat
     3661 ttgcttgttt cgttgacgga tcttgcggga gtgtgaaggc gacatatacg ccgcccgatc
     3721 cggactttgg atctttgccc ccgccagccg cgattgcgac aaactgacgg ccatccacct
     3781 cgtatgtggc gggagtcgca tttcccgcga agggcagcga ggtctcccac agcaactccc
     3841 ccgtagtttt gtcgaaggcg cggaatttct tgtcgaagtt cgttgccccg atgaacacaa
     3901 gcccgccagc ggtgacgatc ggcccaccat agttttcagt gcctgtcttc ttttgtcctt
     3961 gagccgtgag ttctggatac tcgcccagcg gaatcttcca cagatattcg ccggtgttga
     4021 gattgattgc atttaaggtg ccccacggcg gcgccaccgc cgggtatcct ccagaatcca
     4081 gaaatctttt gtagcccgta aaacggtacg gcgcattgcc tgaaatttga gccgaaccac
     4141 caagttcctt attctccccg ctcgtcagat agccgaccaa gacggaggtc tgatcgtcgg
     4201 ccaagtttgg aaatccgggc attctcccct ttccattcct aatggtcgct gtaatctgcg
     4261 cgcgagtcag ccgggtttcc acgccgacaa gagacgggaa cgcgggcggc gagcccgtca
     4321 ttctttcgcc gtggcagacg ctgcactggc tcatgtagat cgctttggcg ctgttgtcgc
     4381 cggcattctc ggcgagcgtt ccagtccacg cgatgtcgtt cgcattgacg tagatgaccc
     4441 cggtttccga atcgactgct ggaccacccc actctgctcc accgtcgaag ccgggaaaga
     4501 tgacggtgtc cttgccaatg cttaaaggga cgaactggcc ttcgctgcgg aacgttctga
     4561 attgttccag cgcccactga tgagcttcgg gcgtgcgcgt ggtcagcatg acttccgtga
     4621 gcaactgacg ggcgaaaggc gcgggcttca tcggaagcgg ctgctcagaa gcggctttct
     4681 cgcccggcac ggtgcttgcc ggatatttcc gttcctcgat cggaaacagc ggattgccat
     4741 tcgcgcgatt gaaaagatac acgaatccct gcttcgtagt ttgcgcaacc gcatccacac
     4801 tgtgtccgtc gcgattcaaa gtcagcagtg ccggtgatgc gggaaagtcg cgatcccaga
     4861 tatcgtggcg cactccttga aaatgccaga ttctttcacc ggtctcagca ttcagagcaa
     4921 gcaggcaatt ggcgaacaga tcgtcgccga tgcgatcgcc gccgtagaaa tcaaatgcgg
     4981 cagatccggt gggaacatag acgatgcctc gcttggcatc cagcgcgaat cccgcccagt
     5041 tgttagccgc gccgctggtc ttccatgcat ccttgggcca tgtgtcgtac ccaaattcgc
     5101 cgggatgcgg gatggtatga aatgcccagc gcatcttccc cgtgcgcacg tcgaaggcgc
     5161 gaacgtcgcc cggaggcgcg ggcagcgttt cgggattgcg ccctccgact ataaccagat
     5221 ctttgtaaat cgcgccgggg ctggtgagat aaacagattg cgcggacgcc ggctcgcgtc
     5281 ctagattgtc gcgcaggtcg attcgcccct gatcgccgaa actcggaatc ggcttgcccg
     5341 tcgcggcatc cagggcgtaa agaaagttca tcacgccgac caggatgcgc ccgtcttttt
     5401 tcttgacctc tttgttgacg ccggaatctc cgtcacctgg ccagtacgcc agccctcggt
     5461 ccggctgcgt gccgagaatt ccggagtcga acctccacaa aagtttccca gtcgccgcat
     5521 cgagtgcgaa tatcttctcc gtgggagtaa tgccatagag cacgccatcg acgacgatag
     5581 gagtcgtttg caacccgccc acttcctgcg tatcaaactt ccaggcgacg gcgagcttcc
     5641 gcacgttggt gcgattgatt tgcgcaagcg aagagtaatg attgttctca ggagagccgc
     5701 cgtaggaagg ccagttttgt tgagcaactc cgaacggaac ggttgcggtc gccatcagga
     5761 aaatcaattc aaccactcgt gggatgaaag agttcatttg tctcaagcgc aatttcctcg
     5821 tcgcccggcg aatcttacca aacgccacgg caatcgcgta acggattacc ccttgacgcg
     5881 cgtacctcaa ttttgtagca tcaatagaac gagttcgctt ttcggagcgg acttgggatt
     5941 tcatgaagag tggctgaggg acgagccctt tgacgccaca gcaaccggat ccggatcata
     6001 tatcctgacc gctggtgcta actctctcct ggaaacggga cacatgagat tcggcatgcg
     6061 agctttttta tttgcgttcc gagcctcatt tccatttccc ggaaattgag gccttttgct
     6121 tttagggcgc tttttgctgg ctcgtcctcg gctactcgca caactcgcga tcaaaagttc
     6181 gatgagatcg aacttggatc aagatcgcga ctgaaaagaa agcgagtggc aacatggctt
     6241 acgaactgcg gtgccgggaa tgcggtcgaa gctggggcaa tcagcctcgc tcgatctgcc
     6301 acgattgttt ctctcctctg gaagtcgcct acgactatga cgcggcgcgc gcgtccataa
     6361 gcctcaaaga aatcgcacag cggccgccga acatgtggcg ttactccgaa ctgctgccgc
     6421 tgcccgcgag attcgagccg cgcctgcccg tgggctttac cccgttgttg caggctccgc
     6481 gcctgggagc gaagctgggc ggaaagtttg ccgcgaagaa tgtctacatc aagaatgacg
     6541 ccgtctgcct gcccacgctg agcttcaagg atcgcgtcgt agccgtcgcg ctggcccagg
     6601 catgcgagtt cggcttcgat accgtctcgt gctcttccac gggcaatctc gctaacgcgg
     6661 tcgccgctca cgctgcgcgc ctgggattga aggcctgggt cttcatccct gccgatctgg
     6721 aacccgcgaa aattctcggc accaatgttt tcggcgccac agtcgttcgc gtcaacggca
     6781 gctacgatca ggtcaaccgt ttgtgttcgc aaattgccga agagcatcct tggggcttcg
     6841 tcaacgtgaa cctgcgtcct tattactccg agggatcgaa gaccgtgggc tttgaaattg
     6901 ccgagcaact gggctggcgg ctgcctgata acgtagtctg ccccatggct ggcggatcgt
     6961 tgatcatcaa aatcaaaaag gcattcgacg aactcgtgaa agtaggattg gtggaagcga
     7021 aggaagtgaa gttctttggc gcgcaagcca caggatgttc gccgatctcg accgcagtaa
     7081 agaccgcaag ctccgaaatc gagccgcaaa aaccggcgac gattgcccgt tcacttgcta
     7141 tcggaaatcc cgccgacggc ctctacgcga ttaagaccat caagcaaagc ggtggctgga
     7201 gcgaagacgt gagcgatccc gaagtcgtcg attcgattcg attgcttgcc gaaaccgaag
     7261 gcgttttcac ggaaaccgca ggcggcgtga cggttggcgt agccggcaag ctctatcgcc
     7321 aggatcgaat cctcccggaa gaaacgactg tgctgtgcat cactggcaat ggcctgaaga
     7381 ccaccgatgc gttgaacgga gtgttcgaag ccgaaactcc aatcgcgccc aagcttgctg
     7441 agttcgagaa ttatctccag cgaacgctgg atacctcgga tgcggataag cagtttgccg
     7501 tcgctgccgg cgtttgagga aattcgcgca ggcagttcac tcatgctgct tgcgcgccaa
     7561 tttcttctcg cgatacatga cgtggtctgc acgctcgatc aacttggcca gcgtctcgcc
     7621 gcgattccat tccgcgactc caaccgaggc acgcacttga agcttcagcg gctcctttcg
     7681 gcccgtagcc ggtagcgtgt actcgccaaa aacccacttc tcaattctct caatttgcgc
     7741 tcgcgcggat gtccggtcgc aagtgagcag caacacgaac tcgtctccac cccagcgtcc
     7801 cgcaatgtca gttgagcgga tattagtgcg cacctcctcg gagaattgca ccagcaaagc
     7861 atctccgacc gtgtggccgt gcgtgtcatt cacctgcttg aatccatcga gatcaagcac
     7921 cacgacgcag aacggccgct gttcggtaat cgccaactcg attcgttgtt ccatgctgcg
     7981 ccggttgaaa agtccggtga gactgtcctt ggaggcaacc gtctcggctt cgcgcagccg
     8041 tgtttcatag gtcgagacct cggccttcag cgcggtaatt gctcgccggt tttcctccgc
     8101 catctggtcg acgcagcctt taagttccgt ggctttgcgc accagcgagg cgcgaacctg
     8161 acccagatct tccaggtcgg cgatggcttc caactgacgg gtaagctcca gcatttggcc
     8221 ggaatatcgc aagtcacgct ggcccatcga ttccgcagtg cgggccagcg caatcagcaa
     8281 ttccttcacc tcgccggttt tcgacttgca gtattcggcg gcgcgcattc cccacacgtc
     8341 caactgctcg gccacactct tttccgtctc ttgcaccaaa gaaaaagatg gaacctcttc
     8401 caggccgctc tgcaacctgg ccaaggctgt cagcaaatcc gaggcaaccg cagggatcgc
     8461 gcgagcgcca ttttctccca ccgatgcgat ggtcgaacgg taagcttgca tgagggcagt
     8521 gaccagcggg ctgggttccg aagcagtctg ttcgacttgg ccgctggata tgtccagata
     8581 tttcttgatg gagatcacgg aagacctttc tcctgaaact acagaagaga aagatcggca
     8641 gaacgagacc caaactttaa cggtgcggcg gcgcacggat tacggtggtg ttctcaacgc
     8701 gccatgaata tcaagccagc gcaaacttgc aactcggcag atcgaaaaga ttcgaatcag
     8761 gatttcgaat caaatgaaga gagcggcagt tagcccgccg ccctcgcaac aaccgtgcgt
     8821 gtctaaaatt gcgtgttaag cgtacctatt cgtcgccgct ggtttctccc ggcaacgcca
     8881 tctggctttg gaaggcggag aagtcgacca gagaatccaa atccttagga tcggtcggct
     8941 tctccagccg tcgttgtact tttttctccg tcttctcgcg ctgcttatcc tgacgcgagc
     9001 gctccttttg tctcttgtta aaacttgtgc gtcctgccat gggcacacct cctcaaaaat
     9061 aaatttggca acgcagactt cacccgcgaa cctcggcaac cgcacggctc gctcgcaatg
     9121 cagagttgct gacttaccag cgcggttcgc gcggctggcg tgcgtggcct tgatagtcgt
     9181 cgcgtccacc accgccaccg ctggaccgtc cgccacctcc acccgaacgg ccaccaccgc
     9241 ctccgggacg tcctccacca cccggacgac caccaccgcc cggacgagcg ccacgaaatc
     9301 cgccgccacc gccttcggtc ttcggccgtg cctcattgat gttcaatgcg cgtccaccaa
     9361 gctctttgcc gttcaaggct gcaatcgcct tttcggcttc ggcggcatcg ttcatttcca
     9421 cgaaggcaaa tccgcgggag cgtcccgttt cgcgctcggt cacaatgctg acctgtgcaa
     9481 tggccccgtg gggctcaaac aaatttcgca gttccgcttc tgtggtgctg tgcgggatgt
     9541 tgccaacaaa tagcttcttc ataaactttc ctcgctggtt atggttcgct ggaacagcca
     9601 tggcgcatgc aagcgccgaa tcgcggctaa ggctgaatat ccgttttgct cgcgggcggt
     9661 gtggagagtg gagctttagc tgccgcatgc ggggtttggc cgccggcggt tatgagtcca
     9721 tgcaccaaaa ttcgatttcg ctggcgctga aaaattcgtt gcttgcgcac gcggttgaag
     9781 cgcgacttgt cgccattgat cgatgacatc gcattcctcc tgattgacgc ggttatgcgc
     9841 ccgatgaaac aggtcgtctc aatcgcgaag gcgcagattt aggtttgcga tgtgtcttcg
     9901 agagtaagct cgataacgat tatacctgtt ttgccgtttt acgcagcgcg acaattttcg
     9961 cgcgctctta gaggtcgccg tccgcaaggg cggggtagcg aacgcacatg catgtcagcg
    10021 tgcgccgttc cactgcgctt gaatcttcgg cgggcgcaac aacgtctgca agaccacgca
    10081 gtattgctcc gtcttttccc cgagtaagcg cagttgttcc ggcgtcgcct caggcgcgtc
    10141 aacattaaat cgcacgcgaa tggcgtcaaa acccaccggc acttccttgg aaatccccaa
    10201 cgttcccgac aagtccatat ctccgtcgac cgtcacttca atctggcgtg tctgaattcc
    10261 catcgccgta gccaccagtt ggcaggtaag ctgcgcgcaa gccgccagtg ctcctagtag
    10321 aagatcgccg gagcatgccg cggtgccggc cccgcctacg cctttgtgcg cctcggcctg
    10381 ataaatggcg cggccgatat cgacggagca ggaaagcggc gtggccgtct cgctgccctt
    10441 tgccgtgaga gtaatccgag agctggccgg atcgcgccgg tactgctcct tcaatggctt
    10501 ctgaagcgat ctgatatccg taacggcttt atccataagg cctccgaact atgattccac
    10561 taaatttaat ttcacacacc gcccgcaaac tccgaactac gtcccgaacc tttcccgata
    10621 tgcgctcggc gcaactcccg tatgcctctg aaacagcgag cggaaaaatg cgacatcctg
    10681 atatcccacg gcgtcactga tctcctgcat ggagcggtga ttgctctcca gcattcgctt
    10741 ggccgcggca acccgcaatt tctgcaggta gatcaacgga ctgtctcccg tcgcctgctt
    10801 aaaacggcgc acgaaattac gtacgctcat gcctacgcgc ctcgctggct cttcaagtga
    10861 aaaagtcttg gcgaaattcc cgtgcatcca ctcctgcgcg ctggaaatcg agtcatccgt
    10921 atggtcggtt ttcaaaggaa caatcgcgaa ccccgactgc caggcgcgcg gcgtttcgat
    10981 gagcagcgcc ttcgcggtct gcaccgcaat ctcgtgcccg caaaatcttt ccaccagata
    11041 aatgctgagg tcgagtgacg cgttcactcc gccgccacag taaaagccgt ggtcttcggt
    11101 caccatcagt tccggcatcc acttcacctt cggatatttt tcgcggaacc gctccgccaa
    11161 tccccagtga gtggtggcgc gcttgccatc aagcaatcct gccgccgcga caagccctac
    11221 tcccgagcac acgctcgcaa tcgacacgtc cttcgcgctg cggcgcttca accacggcac
    11281 aatcgcagcg ttgcgctcga ccacgtcgtc cacgctgagc cccgtcgtcg gcacgaagat
    11341 gagatcggtt ttgcccacat ctttgagtgc gacgttcggt cgaatctgaa tctctccgtc
    11401 gcagttgaca gggcgtccgt ccgccgacgc ggtgatcaca tggaagctgg gagccagcgt
    11461 cgacccggta agaatgttcc acagcgatcc tgcatggcgg aagacttcca tcggcccaat
    11521 cgccgtagag gaaaacatct ggtcgagaag caggatcgtg atctccttca tgttgcgcct
    11581 cgcaatcgtc gaatcccgaa tgtcccccaa aaaggtgtct ggcctaaacg cctacctaca
    11641 atggcatatg tgccatcttg ttgcaagttg attttgcgcc tagtttggat catcgaacgc
    11701 ggatgattcg aaattacgcg aggaattgaa tacacaaatg gcaaccgcgc aaaagcttcc
    11761 caaaatagtc aatggtgtca acgttaccga tttattcgcg accatcgatg ccatcaaagc
    11821 cactcccgcg atcgcgaaat tcaagtttcg cattcacaac caatggaacg gagccagcca
    11881 gaaccgctcg acggtgaaca agtttcacgg cgctgatcag gagctatcgc gggcgaagcc
    11941 gtttgtgttg gaggccgatg agcctgccgt tcttctcggc aaggacactg cggcgaatcc
    12001 tgtggagcat ttgctgcatg cgctggcttc ttgcctgacc acatccatgg tctatcacgc
    12061 tgcggcgcgt ggaattcgga ttgaggaagt tgaatctcag tttgaaggcg atctcgatct
    12121 gcatggattt ctcgatctcg acaaaaacgt gcgtaacgga taccaggggg ttcgagtcaa
    12181 cttcaagatc aaggctgacg tggctgacga gcagttgcag gaaattgttg agctgggaac
    12241 gggacattct ccggtgttcg attgcctgac caacggagtt ccggtttcgg tgaacgcgga
    12301 acggctttag cgctgcgcat tcatttcgtc gaatttattc ggtcaacttt atttggtcaa
    12361 caaaacgaat tttcggcaaa gagatgactt tgccagggcc gcgcaagtgt cctcagtcga
    12421 ccggggacga gaaaaaaatc gaccacacaa gcgacaaagg agaactatga cacgcatcac
    12481 aaagctgatt cacgtttcca cgaaagcgat tctgccgctc gcattgctga gcggtcttat
    12541 tacggcctcg ccggtctttg cccagcagcc cgcagagcac tcgatgcact cggcggctcc
    12601 tgtgccggcg caactggtac aagatgttcg cgcggcgacc aagcagttca tcaacgtcaa
    12661 caatgccggc ccggccggct acggaccggc ttttggctgc gtcagcggtc ccgaccacgg
    12721 agccatgggc attcactacg ttaacggcgc tctggtgacc gacggcctga tcgacgttac
    12781 gcatccggaa gcccttatct atgagccggt ggggaatgcg cgccggctgg tgggcgtcga
    12841 gtacatcgtg gatgcggcca cgtggctggc gaacaataac ggcatacctc ctcaactcga
    12901 cggccaggat ttccagttca tcgcggcgcc gaaccgtttt gctctgaatg attttttcga
    12961 gctgcacgtc tgggcttggc gcgataatcc tcagggcgcg ttcgtggact ggaacaacca
    13021 ggtgagttgc gaaggcgagt aaagcattcg ccagcggtca gcttcgaata agtctggttc
    13081 ggataagcct ggtccgaagg cgtttggttc ggatagaaac gtgggatggg attcgcccaa
    13141 cgaatcccat cgtcacgttc cagaacgcag cacgttccag tccctccatg gctgtgcgca
    13201 gccaaaccgg ttccacttcg ggacgacgtt tactttatcg atacctcccg tgcccctccc
    13261 ccccatttct taaattctct ggaatcttcg agttagggga aatttcccgg caaagtacgc
    13321 cgaataaagg acttatgggc aagttatttt aaattatgga gttatgcccc tgtcctatcc
    13381 tccggcgatt cgggaaccac gctgcttttg ctgaggcaat gatgaagcaa agtaaaagta
    13441 cgatgcaagg tcagatgtca cagcgaggct gtggatttct tcgcggtgat ccgtaagagc
    13501 gtcatcgcgt attcatccac ggtcacggtt gcgcccgtca cattcacgat tcgcggtgtg
    13561 ccctcggaag tcgttctgaa tgaggaggac gacggtgaac ctgcacaatg caataacggt
    13621 gtcgcaacag cgactgggga aactgtagcc cagcttagtt ccgcacgaat gaatgaggtg
    13681 tgcgccgctc tacgtttctc cctgggtgcg ctggaaactg agttactgtg aacgttcttg
    13741 tcccgggatt tcccagcccc tttttcaacg tccgtgttcg cgattcgtaa cataggatta
    13801 ccggccttcg ttgatcgtag gattcgcgac ggttcccaag ggtgccgccc ccaaggctgt
    13861 attggcgaga cttaggcaag agagcagggg gcgcaatcga gcctcgcgtt cctgcattcg
    13921 taaaaacctc cgcatttctc gccggacgct gccgccaatg atatgtttcg tgccttcacg
    13981 cgatgcatcc gcagataccg gctgccgccc cagcttggtg atgccaggag gagatatgag
    14041 aatcaacaag gcgacaaact ttcgcaaaac gttcttctgc aaagtcttct tttggacgat
    14101 ctgtgtttgc accatcatga ctacttgcct actcgccagt ctccccgcgt tcgcgcagac
    14161 ctgcgcctcc ggcgattgtc agcctggcct gattaccggc ccatactctg ccgcggaggc
    14221 ggcgcaaaat acggcggtta attttccggt ttgcacgtcg gccgcgtgcc aggcaagcac
    14281 ctgggagaac aatcagatcg aaggcattga cgcgcagcag aacatcggca cgccttacca
    14341 gttttacgat aacgctctca acctcgatac caacatcgct gtggg
//
