3300027499_1 - 7 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00030_3300027.. (original name was: 3300027499.a:Ga0208788_1000149)

Region	Type	From	To	Most similar known cluster		Similarity
Region 30.1	bacteriocin	1	7,399

c00031_3300027.. (original name was: 3300027499.a:Ga0208788_1000006)

Region	Type	From	To	Most similar known cluster		Similarity
Region 31.1	arylpolyene	180,470	224,075

c00044_3300027.. (original name was: 3300027499.a:Ga0208788_1000012)

Region	Type	From	To	Most similar known cluster		Similarity
Region 44.1	NRPS,T1PKS	97,215	154,174

c00048_3300027.. (original name was: 3300027499.a:Ga0208788_1000031)

Region	Type	From	To	Most similar known cluster		Similarity
Region 48.1	TfuA-related	18,648	40,187

c00053_3300027.. (original name was: 3300027499.a:Ga0208788_1000060)

Region	Type	From	To	Most similar known cluster		Similarity
Region 53.1	NAGGN	40,928	55,705

c00058_3300027.. (original name was: 3300027499.a:Ga0208788_1000043)

Region	Type	From	To	Most similar known cluster		Similarity
Region 58.1	betalactone	43,334	66,609

c00062_3300027.. (original name was: 3300027499.a:Ga0208788_1000004)

Region	Type	From	To	Most similar known cluster		Similarity
Region 62.1	NRPS	244,990	320,674

Region	Type	From	To	Similarity
Region 30.1	bacteriocin	1	7,399
Region 31.1	arylpolyene	180,470	224,075
Region 44.1	NRPS,T1PKS	97,215	154,174
Region 48.1	TfuA-related	18,648	40,187
Region 53.1	NAGGN	40,928	55,705
Region 58.1	betalactone	43,334	66,609
Region 62.1	NRPS	244,990	320,674

No secondary metabolite regions were found in these records:: c00001_3300027.. (original name was: 3300027499.a:Ga0208788_1002901); c00002_3300027.. (original name was: 3300027499.a:Ga0208788_1006494); c00003_3300027.. (original name was: 3300027499.a:Ga0208788_1000567); c00004_3300027.. (original name was: 3300027499.a:Ga0208788_1009156); c00005_3300027.. (original name was: 3300027499.a:Ga0208788_1011844); c00006_3300027.. (original name was: 3300027499.a:Ga0208788_1010047); c00007_3300027.. (original name was: 3300027499.a:Ga0208788_1007841); c00008_3300027.. (original name was: 3300027499.a:Ga0208788_1005530); c00009_3300027.. (original name was: 3300027499.a:Ga0208788_1004378); c00010_3300027.. (original name was: 3300027499.a:Ga0208788_1004146); c00011_3300027.. (original name was: 3300027499.a:Ga0208788_1003935); c00012_3300027.. (original name was: 3300027499.a:Ga0208788_1000077); c00013_3300027.. (original name was: 3300027499.a:Ga0208788_1000131); c00014_3300027.. (original name was: 3300027499.a:Ga0208788_1001294); c00015_3300027.. (original name was: 3300027499.a:Ga0208788_1000033); c00016_3300027.. (original name was: 3300027499.a:Ga0208788_1000029); c00017_3300027.. (original name was: 3300027499.a:Ga0208788_1000045); c00018_3300027.. (original name was: 3300027499.a:Ga0208788_1000032); c00019_3300027.. (original name was: 3300027499.a:Ga0208788_1006531); c00020_3300027.. (original name was: 3300027499.a:Ga0208788_1001620); c00021_3300027.. (original name was: 3300027499.a:Ga0208788_1000069); c00022_3300027.. (original name was: 3300027499.a:Ga0208788_1000023); c00023_3300027.. (original name was: 3300027499.a:Ga0208788_1000002); c00024_3300027.. (original name was: 3300027499.a:Ga0208788_1000049); c00025_3300027.. (original name was: 3300027499.a:Ga0208788_1000005); c00026_3300027.. (original name was: 3300027499.a:Ga0208788_1000256); c00027_3300027.. (original name was: 3300027499.a:Ga0208788_1000021); c00028_3300027.. (original name was: 3300027499.a:Ga0208788_1000007); c00029_3300027.. (original name was: 3300027499.a:Ga0208788_1000008); c00032_3300027.. (original name was: 3300027499.a:Ga0208788_1000015); c00033_3300027.. (original name was: 3300027499.a:Ga0208788_1010638); c00034_3300027.. (original name was: 3300027499.a:Ga0208788_1004527); c00035_3300027.. (original name was: 3300027499.a:Ga0208788_1000113); c00036_3300027.. (original name was: 3300027499.a:Ga0208788_1000019); c00037_3300027.. (original name was: 3300027499.a:Ga0208788_1000066); c00038_3300027.. (original name was: 3300027499.a:Ga0208788_1000119); c00039_3300027.. (original name was: 3300027499.a:Ga0208788_1000410); c00040_3300027.. (original name was: 3300027499.a:Ga0208788_1000406); c00041_3300027.. (original name was: 3300027499.a:Ga0208788_1000018); c00042_3300027.. (original name was: 3300027499.a:Ga0208788_1000526); c00043_3300027.. (original name was: 3300027499.a:Ga0208788_1000041); c00045_3300027.. (original name was: 3300027499.a:Ga0208788_1000035); c00046_3300027.. (original name was: 3300027499.a:Ga0208788_1010166); c00047_3300027.. (original name was: 3300027499.a:Ga0208788_1000078); c00049_3300027.. (original name was: 3300027499.a:Ga0208788_1000025); c00050_3300027.. (original name was: 3300027499.a:Ga0208788_1000219); c00051_3300027.. (original name was: 3300027499.a:Ga0208788_1003726); c00052_3300027.. (original name was: 3300027499.a:Ga0208788_1000040); c00054_3300027.. (original name was: 3300027499.a:Ga0208788_1000014); c00055_3300027.. (original name was: 3300027499.a:Ga0208788_1000328); c00056_3300027.. (original name was: 3300027499.a:Ga0208788_1000067); c00057_3300027.. (original name was: 3300027499.a:Ga0208788_1010907); c00059_3300027.. (original name was: 3300027499.a:Ga0208788_1000050); c00060_3300027.. (original name was: 3300027499.a:Ga0208788_1000100); c00061_3300027.. (original name was: 3300027499.a:Ga0208788_1000003); c00063_3300027.. (original name was: 3300027499.a:Ga0208788_1002304); c00064_3300027.. (original name was: 3300027499.a:Ga0208788_1003177); c00065_3300027.. (original name was: 3300027499.a:Ga0208788_1000026); c00066_3300027.. (original name was: 3300027499.a:Ga0208788_1000009); c00067_3300027.. (original name was: 3300027499.a:Ga0208788_1000071); c00068_3300027.. (original name was: 3300027499.a:Ga0208788_1000011)

Compact view

c00030_3300027.. - Region 1 - bacteriocin

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Location: 1 - 7,399 nt. (total: 7,399 nt) Show pHMM detection rules used

Region on contig edge.

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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c00031_3300027.. - Region 1 - arylpolyene

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Location: 180,470 - 224,075 nt. (total: 43,606 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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c00044_3300027.. - Region 1 - NRPS,T1PKS

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Location: 97,215 - 154,174 nt. (total: 56,960 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 97214 - 154174:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg44_101

Search NORINE for peptide: strict or relaxed

AMP-binding (79..340): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: tGGMiGigpK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 50% (weak)

ctg44_108

PKS_AT (526..805): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; CE-Malonyl-CoA: 54.2%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 105.5
Methoxymalonyl-CoA: 60.9
Methylmalonyl-CoA: 57.3
Ethylmalonyl-CoA: 40.5
Isobutyryl-CoA: 35.0
Propionyl-CoA: 31.6
inactive: 26.5
2-Methylbutyryl-CoA: 25.7
fatty_acid: 19.6
trans-1,2-CPDA: 17.0
CHC-CoA: 10.8
Acetyl-CoA: 9.7
Benzoyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ctg44_109

Search NORINE for peptide: strict or relaxed

AMP-binding (1..357): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

c00048_3300027.. - Region 1 - TfuA-related

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Location: 18,648 - 40,187 nt. (total: 21,540 nt) Show pHMM detection rules used

TfuA-related: ((YcaO or TIGR03882) and TfuA)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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c00053_3300027.. - Region 1 - NAGGN

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Location: 40,928 - 55,705 nt. (total: 14,778 nt) Show pHMM detection rules used

NAGGN: ((TIGR03104 or cds(GATase_7 and Asn_synthase)) and TIGR03103 and (TIGR03106 or Peptidase_M42))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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c00058_3300027.. - Region 1 - betalactone

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Location: 43,334 - 66,609 nt. (total: 23,276 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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c00062_3300027.. - Region 1 - NRPS

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Location: 244,990 - 320,674 nt. (total: 75,685 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 244989 - 320674:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (X - X - ser - D-ser) + (D-asp - X) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg62_279

Search NORINE for peptide: strict or relaxed

AMP-binding (410..803): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGhVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

ctg62_280

Search NORINE for peptide: strict or relaxed

AMP-binding (475..870): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

AMP-binding (1969..2374): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiWeLtadDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 50% (weak)

ctg62_281

Search NORINE for peptide: strict or relaxed

AMP-binding (477..881): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiWeLtadDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 50% (weak)

AMP-binding (1551..1952): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSaeLGtVDK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 70% (weak)

AMP-binding (2608..2996): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (3640..4028): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg62_282

Search NORINE for peptide: strict or relaxed

AMP-binding (420..812): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSaLiAEVwK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)

ctg62_284

CAL_domain (37..479): pk

minowa: NH2

Prediction, score:

NH2: 105.6
fatty_acid: 30.7
shikimic_acid: 13.8
AHBA: 1.7
Acetyl-CoA: -0.9