3300027607_16 - 7 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00003_3300027.. (original name was: 3300027607.a:Ga0207422_1000034)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	NRPS	281,893	326,062

c00004_3300027.. (original name was: 3300027607.a:Ga0207422_1001414)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	NRPS	1,774	47,540

c00005_3300027.. (original name was: 3300027607.a:Ga0207422_1000074)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	terpene	105,766	127,052

c00015_3300027.. (original name was: 3300027607.a:Ga0207422_1000038)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	terpene	212,253	233,185

c00016_3300027.. (original name was: 3300027607.a:Ga0207422_1000031)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	NRPS,T1PKS	1	36,925
Region 16.2	bacteriocin	115,461	130,970

c00017_3300027.. (original name was: 3300027607.a:Ga0207422_1000201)

Region	Type	From	To	Most similar known cluster		Similarity
Region 17.1	terpene	171,809	193,519

Region	Type	From	To	Similarity
Region 3.1	NRPS	281,893	326,062
Region 4.1	NRPS	1,774	47,540
Region 5.1	terpene	105,766	127,052
Region 15.1	terpene	212,253	233,185
Region 16.1	NRPS,T1PKS	1	36,925
Region 16.2	bacteriocin	115,461	130,970
Region 17.1	terpene	171,809	193,519

No secondary metabolite regions were found in these records:: c00001_3300027.. (original name was: 3300027607.a:Ga0207422_1000568); c00002_3300027.. (original name was: 3300027607.a:Ga0207422_1000308); c00006_3300027.. (original name was: 3300027607.a:Ga0207422_1000304); c00007_3300027.. (original name was: 3300027607.a:Ga0207422_1000005); c00008_3300027.. (original name was: 3300027607.a:Ga0207422_1000097); c00009_3300027.. (original name was: 3300027607.a:Ga0207422_1002440); c00010_3300027.. (original name was: 3300027607.a:Ga0207422_1000161); c00011_3300027.. (original name was: 3300027607.a:Ga0207422_1001264); c00012_3300027.. (original name was: 3300027607.a:Ga0207422_1000164); c00013_3300027.. (original name was: 3300027607.a:Ga0207422_1000072); c00014_3300027.. (original name was: 3300027607.a:Ga0207422_1000153); c00018_3300027.. (original name was: 3300027607.a:Ga0207422_1001144); c00019_3300027.. (original name was: 3300027607.a:Ga0207422_1000387)

Compact view

c00003_3300027.. - Region 1 - NRPS

Download region GenBank file

Location: 281,893 - 326,062 nt. (total: 44,170 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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core biosynthetic genes

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 281892 - 326062:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg3_231

Search NORINE for peptide: strict or relaxed

AMP-binding (523..914): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGmVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

c00004_3300027.. - Region 1 - NRPS

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Location: 1,774 - 47,540 nt. (total: 45,767 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 1773 - 47540:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (asn) + (gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg4_17

Search NORINE for peptide: strict or relaxed

AMP-binding (468..855): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg4_19

Search NORINE for peptide: strict or relaxed

AMP-binding (503..888): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSaLiAEVwK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)

ctg4_20

Search NORINE for peptide: strict or relaxed

AMP-binding (471..867): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

ctg4_24

Search NORINE for peptide: strict or relaxed

AMP-binding (9..428): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DmFYLGvqCK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

c00005_3300027.. - Region 1 - terpene

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Location: 105,766 - 127,052 nt. (total: 21,287 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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c00015_3300027.. - Region 1 - terpene

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Location: 212,253 - 233,185 nt. (total: 20,933 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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c00016_3300027.. - Region 1 - NRPS,T1PKS

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Location: 1 - 36,925 nt. (total: 36,925 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 36925:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - mal - gly) + (gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg16_1

Search NORINE for peptide: strict or relaxed

AMP-binding (519..914): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGmVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

ctg16_2

Search NORINE for peptide: strict or relaxed

AMP-binding (521..916): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGmVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

ctg16_3

Search NORINE for peptide: strict or relaxed

AMP-binding (28..431): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSaLiAEVwK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)

PKS_AT (1487..1783): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; inactive: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 123.2
inactive: 70.0
Methoxymalonyl-CoA: 54.1
Methylmalonyl-CoA: 48.7
Isobutyryl-CoA: 31.0
Propionyl-CoA: 30.0
Ethylmalonyl-CoA: 23.3
Benzoyl-CoA: 19.4
fatty_acid: 13.6
2-Methylbutyryl-CoA: 13.3
CHC-CoA: 10.3
Acetyl-CoA: 9.0
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0

AMP-binding (2999..3402): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQfGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

c00016_3300027.. - Region 2 - bacteriocin

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Location: 115,461 - 130,970 nt. (total: 15,510 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

c00017_3300027.. - Region 1 - terpene

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Location: 171,809 - 193,519 nt. (total: 21,711 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it