3300027607_9 - 31 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00004_3300027.. (original name was: 3300027607.a:Ga0207422_1004827)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	T1PKS	1	10,488

c00005_3300027.. (original name was: 3300027607.a:Ga0207422_1003897)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	T1PKS,PKS-like	1	13,517

c00007_3300027.. (original name was: 3300027607.a:Ga0207422_1002301)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	NRPS	1,259	26,445

c00014_3300027.. (original name was: 3300027607.a:Ga0207422_1001527)

Region	Type	From	To	Most similar known cluster		Similarity
Region 14.1	terpene	1	11,455

c00034_3300027.. (original name was: 3300027607.a:Ga0207422_1000946)

Region	Type	From	To	Most similar known cluster		Similarity
Region 34.1	NRPS	20,158	72,258

c00064_3300027.. (original name was: 3300027607.a:Ga0207422_1001009)

Region	Type	From	To	Most similar known cluster		Similarity
Region 64.1	T1PKS,NRPS	1	39,164

c00065_3300027.. (original name was: 3300027607.a:Ga0207422_1000537)

Region	Type	From	To	Most similar known cluster		Similarity
Region 65.1	bacteriocin	74,620	85,693

c00068_3300027.. (original name was: 3300027607.a:Ga0207422_1000212)

Region	Type	From	To	Most similar known cluster		Similarity
Region 68.1	NRPS-like,T1PKS	132,471	180,171

c00075_3300027.. (original name was: 3300027607.a:Ga0207422_1009257)

Region	Type	From	To	Most similar known cluster		Similarity
Region 75.1	T1PKS	1	5,023

c00080_3300027.. (original name was: 3300027607.a:Ga0207422_1003120)

Region	Type	From	To	Most similar known cluster		Similarity
Region 80.1	T1PKS,NRPS	1	17,908

c00083_3300027.. (original name was: 3300027607.a:Ga0207422_1000595)

Region	Type	From	To	Most similar known cluster		Similarity
Region 83.1	T1PKS,NRPS-like	42,665	90,047

c00085_3300027.. (original name was: 3300027607.a:Ga0207422_1001371)

Region	Type	From	To	Most similar known cluster		Similarity
Region 85.1	T1PKS,NRPS	1	49,461

c00088_3300027.. (original name was: 3300027607.a:Ga0207422_1002888)

Region	Type	From	To	Most similar known cluster		Similarity
Region 88.1	NRPS	1	19,755

c00091_3300027.. (original name was: 3300027607.a:Ga0207422_1002840)

Region	Type	From	To	Most similar known cluster		Similarity
Region 91.1	NRPS	1	20,313

c00094_3300027.. (original name was: 3300027607.a:Ga0207422_1002335)

Region	Type	From	To	Most similar known cluster		Similarity
Region 94.1	bacteriocin	3,618	14,466

c00113_3300027.. (original name was: 3300027607.a:Ga0207422_1005212)

Region	Type	From	To	Most similar known cluster		Similarity
Region 113.1	NRPS	1	9,573

c00119_3300027.. (original name was: 3300027607.a:Ga0207422_1000658)

Region	Type	From	To	Most similar known cluster		Similarity
Region 119.1	CDPS	21,788	42,399
Region 119.2	NRPS-like	76,087	97,700

c00120_3300027.. (original name was: 3300027607.a:Ga0207422_1000857)

Region	Type	From	To	Most similar known cluster		Similarity
Region 120.1	T1PKS	45,692	78,883

c00127_3300027.. (original name was: 3300027607.a:Ga0207422_1004434)

Region	Type	From	To	Most similar known cluster		Similarity
Region 127.1	NRPS,T1PKS	1	11,670

c00132_3300027.. (original name was: 3300027607.a:Ga0207422_1005527)

Region	Type	From	To	Most similar known cluster		Similarity
Region 132.1	T1PKS	1	8,933

c00134_3300027.. (original name was: 3300027607.a:Ga0207422_1001373)

Region	Type	From	To	Most similar known cluster		Similarity
Region 134.1	NRPS,T1PKS	5,603	49,424

c00139_3300027.. (original name was: 3300027607.a:Ga0207422_1001191)

Region	Type	From	To	Most similar known cluster		Similarity
Region 139.1	terpene	1	20,698

c00143_3300027.. (original name was: 3300027607.a:Ga0207422_1000783)

Region	Type	From	To	Most similar known cluster		Similarity
Region 143.1	T1PKS	1	62,758

c00148_3300027.. (original name was: 3300027607.a:Ga0207422_1000800)

Region	Type	From	To	Most similar known cluster		Similarity
Region 148.1	NRPS	17,724	66,738

c00155_3300027.. (original name was: 3300027607.a:Ga0207422_1001110)

Region	Type	From	To	Most similar known cluster		Similarity
Region 155.1	NRPS	1	37,125

c00156_3300027.. (original name was: 3300027607.a:Ga0207422_1001886)

Region	Type	From	To	Most similar known cluster		Similarity
Region 156.1	NRPS-like	5,662	33,954

c00160_3300027.. (original name was: 3300027607.a:Ga0207422_1000450)

Region	Type	From	To	Most similar known cluster		Similarity
Region 160.1	NRPS-like	1	35,606

c00162_3300027.. (original name was: 3300027607.a:Ga0207422_1001246)

Region	Type	From	To	Most similar known cluster		Similarity
Region 162.1	cyanobactin	42,213	54,420

c00170_3300027.. (original name was: 3300027607.a:Ga0207422_1000420)

Region	Type	From	To	Most similar known cluster		Similarity
Region 170.1	NRPS-like,T1PKS	44,818	93,454

c00173_3300027.. (original name was: 3300027607.a:Ga0207422_1000860)

Region	Type	From	To	Most similar known cluster		Similarity
Region 173.1	T1PKS,NRPS	2,695	78,633

Region	Type	From	To	Similarity
Region 4.1	T1PKS	1	10,488
Region 5.1	T1PKS,PKS-like	1	13,517
Region 7.1	NRPS	1,259	26,445
Region 14.1	terpene	1	11,455
Region 34.1	NRPS	20,158	72,258
Region 64.1	T1PKS,NRPS	1	39,164
Region 65.1	bacteriocin	74,620	85,693
Region 68.1	NRPS-like,T1PKS	132,471	180,171
Region 75.1	T1PKS	1	5,023
Region 80.1	T1PKS,NRPS	1	17,908
Region 83.1	T1PKS,NRPS-like	42,665	90,047
Region 85.1	T1PKS,NRPS	1	49,461
Region 88.1	NRPS	1	19,755
Region 91.1	NRPS	1	20,313
Region 94.1	bacteriocin	3,618	14,466
Region 113.1	NRPS	1	9,573
Region 119.1	CDPS	21,788	42,399
Region 119.2	NRPS-like	76,087	97,700
Region 120.1	T1PKS	45,692	78,883
Region 127.1	NRPS,T1PKS	1	11,670
Region 132.1	T1PKS	1	8,933
Region 134.1	NRPS,T1PKS	5,603	49,424
Region 139.1	terpene	1	20,698
Region 143.1	T1PKS	1	62,758
Region 148.1	NRPS	17,724	66,738
Region 155.1	NRPS	1	37,125
Region 156.1	NRPS-like	5,662	33,954
Region 160.1	NRPS-like	1	35,606
Region 162.1	cyanobactin	42,213	54,420
Region 170.1	NRPS-like,T1PKS	44,818	93,454
Region 173.1	T1PKS,NRPS	2,695	78,633

No secondary metabolite regions were found in these records:: c00001_3300027.. (original name was: 3300027607.a:Ga0207422_1009975); c00002_3300027.. (original name was: 3300027607.a:Ga0207422_1007312); c00003_3300027.. (original name was: 3300027607.a:Ga0207422_1005875); c00006_3300027.. (original name was: 3300027607.a:Ga0207422_1000808); c00008_3300027.. (original name was: 3300027607.a:Ga0207422_1000665); c00009_3300027.. (original name was: 3300027607.a:Ga0207422_1006413); c00010_3300027.. (original name was: 3300027607.a:Ga0207422_1004683); c00011_3300027.. (original name was: 3300027607.a:Ga0207422_1005470); c00012_3300027.. (original name was: 3300027607.a:Ga0207422_1005894); c00013_3300027.. (original name was: 3300027607.a:Ga0207422_1004799); c00015_3300027.. (original name was: 3300027607.a:Ga0207422_1008762); c00016_3300027.. (original name was: 3300027607.a:Ga0207422_1007048); c00017_3300027.. (original name was: 3300027607.a:Ga0207422_1003313); c00018_3300027.. (original name was: 3300027607.a:Ga0207422_1004360); c00019_3300027.. (original name was: 3300027607.a:Ga0207422_1003763); c00020_3300027.. (original name was: 3300027607.a:Ga0207422_1003471); c00021_3300027.. (original name was: 3300027607.a:Ga0207422_1003626); c00022_3300027.. (original name was: 3300027607.a:Ga0207422_1000354); c00023_3300027.. (original name was: 3300027607.a:Ga0207422_1004421); c00024_3300027.. (original name was: 3300027607.a:Ga0207422_1003852); c00025_3300027.. (original name was: 3300027607.a:Ga0207422_1004219); c00026_3300027.. (original name was: 3300027607.a:Ga0207422_1001809); c00027_3300027.. (original name was: 3300027607.a:Ga0207422_1003401); c00028_3300027.. (original name was: 3300027607.a:Ga0207422_1007725); c00029_3300027.. (original name was: 3300027607.a:Ga0207422_1002153); c00030_3300027.. (original name was: 3300027607.a:Ga0207422_1003746); c00031_3300027.. (original name was: 3300027607.a:Ga0207422_1006521); c00032_3300027.. (original name was: 3300027607.a:Ga0207422_1003337); c00033_3300027.. (original name was: 3300027607.a:Ga0207422_1003400); c00035_3300027.. (original name was: 3300027607.a:Ga0207422_1001802); c00036_3300027.. (original name was: 3300027607.a:Ga0207422_1003867); c00037_3300027.. (original name was: 3300027607.a:Ga0207422_1003469); c00038_3300027.. (original name was: 3300027607.a:Ga0207422_1003187); c00039_3300027.. (original name was: 3300027607.a:Ga0207422_1003321); c00040_3300027.. (original name was: 3300027607.a:Ga0207422_1004750); c00041_3300027.. (original name was: 3300027607.a:Ga0207422_1001367); c00042_3300027.. (original name was: 3300027607.a:Ga0207422_1001243); c00043_3300027.. (original name was: 3300027607.a:Ga0207422_1002545); c00044_3300027.. (original name was: 3300027607.a:Ga0207422_1000876); c00045_3300027.. (original name was: 3300027607.a:Ga0207422_1001336); c00046_3300027.. (original name was: 3300027607.a:Ga0207422_1000463); c00047_3300027.. (original name was: 3300027607.a:Ga0207422_1000913); c00048_3300027.. (original name was: 3300027607.a:Ga0207422_1000714); c00049_3300027.. (original name was: 3300027607.a:Ga0207422_1001917); c00050_3300027.. (original name was: 3300027607.a:Ga0207422_1001247); c00051_3300027.. (original name was: 3300027607.a:Ga0207422_1001285); c00052_3300027.. (original name was: 3300027607.a:Ga0207422_1004270); c00053_3300027.. (original name was: 3300027607.a:Ga0207422_1000721); c00054_3300027.. (original name was: 3300027607.a:Ga0207422_1000831); c00055_3300027.. (original name was: 3300027607.a:Ga0207422_1002383); c00056_3300027.. (original name was: 3300027607.a:Ga0207422_1007347); c00057_3300027.. (original name was: 3300027607.a:Ga0207422_1002969); c00058_3300027.. (original name was: 3300027607.a:Ga0207422_1001974); c00059_3300027.. (original name was: 3300027607.a:Ga0207422_1002878); c00060_3300027.. (original name was: 3300027607.a:Ga0207422_1002480); c00061_3300027.. (original name was: 3300027607.a:Ga0207422_1003628); c00062_3300027.. (original name was: 3300027607.a:Ga0207422_1000643); c00063_3300027.. (original name was: 3300027607.a:Ga0207422_1001796); c00066_3300027.. (original name was: 3300027607.a:Ga0207422_1002129); c00067_3300027.. (original name was: 3300027607.a:Ga0207422_1000970); c00069_3300027.. (original name was: 3300027607.a:Ga0207422_1004391); c00070_3300027.. (original name was: 3300027607.a:Ga0207422_1011803); c00071_3300027.. (original name was: 3300027607.a:Ga0207422_1003062); c00072_3300027.. (original name was: 3300027607.a:Ga0207422_1011221); c00073_3300027.. (original name was: 3300027607.a:Ga0207422_1007304); c00074_3300027.. (original name was: 3300027607.a:Ga0207422_1002858); c00076_3300027.. (original name was: 3300027607.a:Ga0207422_1001768); c00077_3300027.. (original name was: 3300027607.a:Ga0207422_1002564); c00078_3300027.. (original name was: 3300027607.a:Ga0207422_1005732); c00079_3300027.. (original name was: 3300027607.a:Ga0207422_1001757); c00081_3300027.. (original name was: 3300027607.a:Ga0207422_1008425); c00082_3300027.. (original name was: 3300027607.a:Ga0207422_1002558); c00084_3300027.. (original name was: 3300027607.a:Ga0207422_1009749); c00086_3300027.. (original name was: 3300027607.a:Ga0207422_1001769); c00087_3300027.. (original name was: 3300027607.a:Ga0207422_1004356); c00089_3300027.. (original name was: 3300027607.a:Ga0207422_1001296); c00090_3300027.. (original name was: 3300027607.a:Ga0207422_1007266); c00092_3300027.. (original name was: 3300027607.a:Ga0207422_1002641); c00093_3300027.. (original name was: 3300027607.a:Ga0207422_1002243); c00095_3300027.. (original name was: 3300027607.a:Ga0207422_1003529); c00096_3300027.. (original name was: 3300027607.a:Ga0207422_1001686); c00097_3300027.. (original name was: 3300027607.a:Ga0207422_1002777); c00098_3300027.. (original name was: 3300027607.a:Ga0207422_1001810); c00099_3300027.. (original name was: 3300027607.a:Ga0207422_1001412); c00100_3300027.. (original name was: 3300027607.a:Ga0207422_1001024); c00101_3300027.. (original name was: 3300027607.a:Ga0207422_1003350); c00102_3300027.. (original name was: 3300027607.a:Ga0207422_1003151); c00103_3300027.. (original name was: 3300027607.a:Ga0207422_1007471); c00104_3300027.. (original name was: 3300027607.a:Ga0207422_1009262); c00105_3300027.. (original name was: 3300027607.a:Ga0207422_1005651); c00106_3300027.. (original name was: 3300027607.a:Ga0207422_1003266); c00107_3300027.. (original name was: 3300027607.a:Ga0207422_1000895); c00108_3300027.. (original name was: 3300027607.a:Ga0207422_1004079); c00109_3300027.. (original name was: 3300027607.a:Ga0207422_1002597); c00110_3300027.. (original name was: 3300027607.a:Ga0207422_1005781); c00111_3300027.. (original name was: 3300027607.a:Ga0207422_1000446); c00112_3300027.. (original name was: 3300027607.a:Ga0207422_1001817); c00114_3300027.. (original name was: 3300027607.a:Ga0207422_1001832); c00115_3300027.. (original name was: 3300027607.a:Ga0207422_1008200); c00116_3300027.. (original name was: 3300027607.a:Ga0207422_1005812); c00117_3300027.. (original name was: 3300027607.a:Ga0207422_1000768); c00118_3300027.. (original name was: 3300027607.a:Ga0207422_1003046); c00121_3300027.. (original name was: 3300027607.a:Ga0207422_1000954); c00122_3300027.. (original name was: 3300027607.a:Ga0207422_1001480); c00123_3300027.. (original name was: 3300027607.a:Ga0207422_1003669); c00124_3300027.. (original name was: 3300027607.a:Ga0207422_1008814); c00125_3300027.. (original name was: 3300027607.a:Ga0207422_1001849); c00126_3300027.. (original name was: 3300027607.a:Ga0207422_1002842); c00128_3300027.. (original name was: 3300027607.a:Ga0207422_1001136); c00129_3300027.. (original name was: 3300027607.a:Ga0207422_1001613); c00130_3300027.. (original name was: 3300027607.a:Ga0207422_1004399); c00131_3300027.. (original name was: 3300027607.a:Ga0207422_1003139); c00133_3300027.. (original name was: 3300027607.a:Ga0207422_1001174); c00135_3300027.. (original name was: 3300027607.a:Ga0207422_1002970); c00136_3300027.. (original name was: 3300027607.a:Ga0207422_1000781); c00137_3300027.. (original name was: 3300027607.a:Ga0207422_1001179); c00138_3300027.. (original name was: 3300027607.a:Ga0207422_1001761); c00140_3300027.. (original name was: 3300027607.a:Ga0207422_1002010); c00141_3300027.. (original name was: 3300027607.a:Ga0207422_1002972); c00142_3300027.. (original name was: 3300027607.a:Ga0207422_1001579); c00144_3300027.. (original name was: 3300027607.a:Ga0207422_1000947); c00145_3300027.. (original name was: 3300027607.a:Ga0207422_1000748); c00146_3300027.. (original name was: 3300027607.a:Ga0207422_1002738); c00147_3300027.. (original name was: 3300027607.a:Ga0207422_1002591); c00149_3300027.. (original name was: 3300027607.a:Ga0207422_1002175); c00150_3300027.. (original name was: 3300027607.a:Ga0207422_1001578); c00151_3300027.. (original name was: 3300027607.a:Ga0207422_1002772); c00152_3300027.. (original name was: 3300027607.a:Ga0207422_1001270); c00153_3300027.. (original name was: 3300027607.a:Ga0207422_1001469); c00154_3300027.. (original name was: 3300027607.a:Ga0207422_1000717); c00157_3300027.. (original name was: 3300027607.a:Ga0207422_1001090); c00158_3300027.. (original name was: 3300027607.a:Ga0207422_1001927); c00159_3300027.. (original name was: 3300027607.a:Ga0207422_1001095); c00161_3300027.. (original name was: 3300027607.a:Ga0207422_1001047); c00163_3300027.. (original name was: 3300027607.a:Ga0207422_1000903); c00164_3300027.. (original name was: 3300027607.a:Ga0207422_1003291); c00165_3300027.. (original name was: 3300027607.a:Ga0207422_1004883); c00166_3300027.. (original name was: 3300027607.a:Ga0207422_1009147); c00167_3300027.. (original name was: 3300027607.a:Ga0207422_1002779); c00168_3300027.. (original name was: 3300027607.a:Ga0207422_1001518); c00169_3300027.. (original name was: 3300027607.a:Ga0207422_1000742); c00171_3300027.. (original name was: 3300027607.a:Ga0207422_1000118); c00172_3300027.. (original name was: 3300027607.a:Ga0207422_1001656); c00174_3300027.. (original name was: 3300027607.a:Ga0207422_1005636); c00175_3300027.. (original name was: 3300027607.a:Ga0207422_1003447); c00176_3300027.. (original name was: 3300027607.a:Ga0207422_1001402); c00177_3300027.. (original name was: 3300027607.a:Ga0207422_1003713); c00178_3300027.. (original name was: 3300027607.a:Ga0207422_1000529); c00179_3300027.. (original name was: 3300027607.a:Ga0207422_1000917); c00180_3300027.. (original name was: 3300027607.a:Ga0207422_1000455); c00181_3300027.. (original name was: 3300027607.a:Ga0207422_1000798); c00182_3300027.. (original name was: 3300027607.a:Ga0207422_1002589); c00183_3300027.. (original name was: 3300027607.a:Ga0207422_1005972); c00184_3300027.. (original name was: 3300027607.a:Ga0207422_1002045); c00185_3300027.. (original name was: 3300027607.a:Ga0207422_1001366); c00186_3300027.. (original name was: 3300027607.a:Ga0207422_1000784); c00187_3300027.. (original name was: 3300027607.a:Ga0207422_1001182)

Compact view

c00004_3300027.. - Region 1 - T1PKS

Download region GenBank file

Location: 1 - 10,488 nt. (total: 10,488 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 10488:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg4_2

Search NORINE for peptide: strict or relaxed

AMP-binding (10..356): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: iGnpTGtilK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 40% (weak)

ctg4_5

PKS_AT (549..845): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 193.2
inactive: 187.8
Methoxymalonyl-CoA: 49.6
Methylmalonyl-CoA: 45.0
Isobutyryl-CoA: 28.0
Propionyl-CoA: 24.0
Benzoyl-CoA: 13.6
Ethylmalonyl-CoA: 10.8
CHC-CoA: 9.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 91.7%

c00005_3300027.. - Region 1 - PKS-like,T1PKS

Download region GenBank file

Location: 1 - 13,517 nt. (total: 13,517 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
PKS-like: (t2pks2 or ksIII)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 13517:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg5_1

PKS_AT (0..180): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 113.5
inactive: 98.3
Methoxymalonyl-CoA: 39.2
Methylmalonyl-CoA: 27.1
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: (unknown)

No matches above 50%

ctg5_7

PKS_AT (935..1234): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 206.6
inactive: 200.2
Methoxymalonyl-CoA: 69.4
Methylmalonyl-CoA: 62.3
Propionyl-CoA: 36.1
Isobutyryl-CoA: 34.0
Ethylmalonyl-CoA: 21.6
Benzoyl-CoA: 21.5
2-Methylbutyryl-CoA: 20.7
CHC-CoA: 15.4
Acetyl-CoA: 14.3
trans-1,2-CPDA: 13.3
3-Methylbutyryl-CoA: 11.0
fatty_acid: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 91.7%; 2-Rhyd-Malonyl-CoA: 58.3%

ctg5_8

PKS_AT (573..782): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 150.8
inactive: 138.3
Methoxymalonyl-CoA: 42.2
Methylmalonyl-CoA: 35.7
Isobutyryl-CoA: 24.9
Propionyl-CoA: 20.6
Benzoyl-CoA: 16.3
CHC-CoA: 10.3
Ethylmalonyl-CoA: 9.7
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 87.5%

c00007_3300027.. - Region 1 - NRPS

Download region GenBank file

Location: 1,259 - 26,445 nt. (total: 25,187 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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NRPS/PKS domains

Detailed domain annotation

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c00014_3300027.. - Region 1 - terpene

Download region GenBank file

Location: 1 - 11,455 nt. (total: 11,455 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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c00034_3300027.. - Region 1 - NRPS

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Location: 20,158 - 72,258 nt. (total: 52,101 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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NRPS/PKS domains

Detailed domain annotation

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Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 20157 - 72258:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - thr) + (pro - gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg34_33

Search NORINE for peptide: strict or relaxed

AMP-binding (30..448): X

NRPSPredictor2: gly, ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVpSItlVwK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 60% (weak)

AMP-binding (1529..1941): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg34_35

Search NORINE for peptide: strict or relaxed

AMP-binding (8..311): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAqVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 90% (moderate)

AMP-binding (1385..1786): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQiGLVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

c00064_3300027.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 1 - 39,164 nt. (total: 39,164 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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c00065_3300027.. - Region 1 - bacteriocin

Download region GenBank file

Location: 74,620 - 85,693 nt. (total: 11,074 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

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c00068_3300027.. - Region 1 - NRPS-like,T1PKS

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Location: 132,471 - 180,171 nt. (total: 47,701 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 132470 - 180171:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg68_122

CAL_domain (191..484): pk

minowa: NH2

Prediction, score:

NH2: 14.8
shikimic_acid: 0.0
fatty_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

PKS_AT (1238..1535): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 214.3
inactive: 198.9
Methoxymalonyl-CoA: 74.5
Methylmalonyl-CoA: 64.8
Propionyl-CoA: 40.4
Isobutyryl-CoA: 37.5
Ethylmalonyl-CoA: 28.5
Acetyl-CoA: 26.1
Benzoyl-CoA: 24.0
2-Methylbutyryl-CoA: 23.6
3-Methylbutyryl-CoA: 20.3
trans-1,2-CPDA: 19.2
CHC-CoA: 15.9
fatty_acid: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 100.0%; 2-Rhyd-Malonyl-CoA: 54.2%

c00075_3300027.. - Region 1 - T1PKS

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Location: 1 - 5,023 nt. (total: 5,023 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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c00080_3300027.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 1 - 17,908 nt. (total: 17,908 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 17908:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg80_1

PKS_AT (0..192): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 115.6
inactive: 108.4
Methoxymalonyl-CoA: 39.8
Methylmalonyl-CoA: 29.7
Propionyl-CoA: 11.6
3-Methylbutyryl-CoA: 10.2
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: (unknown)

No matches above 50%

ctg80_2

Search NORINE for peptide: strict or relaxed

PKS_AT (569..865): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 215.3
inactive: 198.2
Methoxymalonyl-CoA: 64.6
Methylmalonyl-CoA: 61.4
Propionyl-CoA: 44.3
Isobutyryl-CoA: 38.0
2-Methylbutyryl-CoA: 20.7
Ethylmalonyl-CoA: 18.9
Benzoyl-CoA: 13.1
CHC-CoA: 11.9
Acetyl-CoA: 11.9
trans-1,2-CPDA: 10.0
3-Methylbutyryl-CoA: 8.1
fatty_acid: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 100.0%; 2-Rhyd-Malonyl-CoA: 54.2%

AMP-binding (1803..2172): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVlHlSfgEK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 60% (weak)

c00083_3300027.. - Region 1 - NRPS-like,T1PKS

Download region GenBank file

Location: 42,665 - 90,047 nt. (total: 47,383 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 42664 - 90047:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg83_60

Search NORINE for peptide: strict or relaxed

AMP-binding (10..406): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: vlWtwtytVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 30% (weak)

PKS_AT (1164..1459): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 188.0
inactive: 173.1
Methoxymalonyl-CoA: 62.7
Methylmalonyl-CoA: 57.2
Propionyl-CoA: 34.5
Isobutyryl-CoA: 28.4
Benzoyl-CoA: 26.8
Acetyl-CoA: 24.4
trans-1,2-CPDA: 19.3
CHC-CoA: 15.9
2-Methylbutyryl-CoA: 15.3
fatty_acid: 12.6
Ethylmalonyl-CoA: 12.2
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 91.7%; 2-Rhyd-Malonyl-CoA: 54.2%

c00085_3300027.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 1 - 49,461 nt. (total: 49,461 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 49461:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (ohmal) + (cys) + (trp - phe) + (ohmal) + (ohmal) + (ohmal) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 27644 - 49461:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal) + (ohmal) + (ohmal) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg85_3

Search NORINE for peptide: strict or relaxed

AMP-binding (539..940): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNigiIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 70% (weak)

ctg85_4

PKS_AT (529..767): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 81.8
inactive: 71.0
Methylmalonyl-CoA: 34.2
Methoxymalonyl-CoA: 31.1
Propionyl-CoA: 29.1
Benzoyl-CoA: 27.9
2-Methylbutyryl-CoA: 23.2
Isobutyryl-CoA: 21.3
CHC-CoA: 20.1
Acetyl-CoA: 17.2
Ethylmalonyl-CoA: 16.7
trans-1,2-CPDA: 9.1
3-Methylbutyryl-CoA: 7.3
fatty_acid: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; inactive: 62.5%; Methylmalonyl-CoA: 54.2%

ctg85_5

Search NORINE for peptide: strict or relaxed

AMP-binding (549..948): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLyNMSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)

ctg85_6

Search NORINE for peptide: strict or relaxed

AMP-binding (539..935): trp

NRPSPredictor2: trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVSSIGAVtK
Nearest Stachelhaus code:: trp
Stachelhaus code match:: 90% (moderate)

AMP-binding (1625..2017): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAWtIAAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 90% (moderate)

ctg85_7

PKS_AT (534..830): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 178.2
inactive: 125.8
Methoxymalonyl-CoA: 67.8
Methylmalonyl-CoA: 56.4
Propionyl-CoA: 40.9
CHC-CoA: 28.2
2-Methylbutyryl-CoA: 27.4
Benzoyl-CoA: 26.9
Isobutyryl-CoA: 25.9
Acetyl-CoA: 23.2
Ethylmalonyl-CoA: 21.4
fatty_acid: 14.8
trans-1,2-CPDA: 12.8
3-Methylbutyryl-CoA: 11.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 87.5%; 2-Rhyd-Malonyl-CoA: 54.2%

ctg85_8

PKS_AT (535..837): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 168.3
inactive: 119.9
Methoxymalonyl-CoA: 64.8
Methylmalonyl-CoA: 55.7
Propionyl-CoA: 42.9
2-Methylbutyryl-CoA: 27.6
Isobutyryl-CoA: 24.9
Ethylmalonyl-CoA: 22.2
CHC-CoA: 19.3
Benzoyl-CoA: 18.7
Acetyl-CoA: 17.1
trans-1,2-CPDA: 12.3
3-Methylbutyryl-CoA: 10.0
fatty_acid: 7.9

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 91.7%; Methylmalonyl-CoA: 58.3%

ctg85_9

PKS_AT (535..767): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 98.5
inactive: 69.0
Methylmalonyl-CoA: 36.0
Methoxymalonyl-CoA: 34.9
Propionyl-CoA: 28.8
2-Methylbutyryl-CoA: 27.0
Isobutyryl-CoA: 24.3
Acetyl-CoA: 23.6
CHC-CoA: 22.1
Benzoyl-CoA: 21.8
Ethylmalonyl-CoA: 20.1
trans-1,2-CPDA: 16.2
3-Methylbutyryl-CoA: 13.0
fatty_acid: 11.2

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 70.8%

ctg85_10

PKS_AT (534..863): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 149.2
inactive: 108.1
Methoxymalonyl-CoA: 71.5
Methylmalonyl-CoA: 51.8
Isobutyryl-CoA: 35.8
Propionyl-CoA: 32.2
Ethylmalonyl-CoA: 26.7
Benzoyl-CoA: 25.7
3-Methylbutyryl-CoA: 17.2
Acetyl-CoA: 16.8
CHC-CoA: 13.0
trans-1,2-CPDA: 10.2
fatty_acid: 0.0
2-Methylbutyryl-CoA: -1.8

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 75.0%; 2-Rhyd-Malonyl-CoA: 54.2%

c00088_3300027.. - Region 1 - NRPS

Download region GenBank file

Location: 1 - 19,755 nt. (total: 19,755 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 19755:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg88_4

Search NORINE for peptide: strict or relaxed

AMP-binding (469..879): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGhVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

c00091_3300027.. - Region 1 - NRPS

Download region GenBank file

Location: 1 - 20,313 nt. (total: 20,313 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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NRPS/PKS domains

Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 20313:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg91_2

Search NORINE for peptide: strict or relaxed

AMP-binding (9..409): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGmVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

AMP-binding (1487..1894): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSaLiAEVwK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)

c00094_3300027.. - Region 1 - bacteriocin

Download region GenBank file

Location: 3,618 - 14,466 nt. (total: 10,849 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

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c00113_3300027.. - Region 1 - NRPS

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Location: 1 - 9,573 nt. (total: 9,573 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 9573:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg113_2

Search NORINE for peptide: strict or relaxed

AMP-binding (462..920): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

c00119_3300027.. - Region 1 - CDPS

Download region GenBank file

Location: 21,788 - 42,399 nt. (total: 20,612 nt) Show pHMM detection rules used

CDPS: (CDPS or cycdipepsynth)

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c00119_3300027.. - Region 2 - NRPS-like

Download region GenBank file

Location: 76,087 - 97,700 nt. (total: 21,614 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

Detailed domain annotation

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c00120_3300027.. - Region 1 - T1PKS

Download region GenBank file

Location: 45,692 - 78,883 nt. (total: 33,192 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 45691 - 78883:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg120_45

PKS_AT (838..1136): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 213.0
inactive: 210.8
Methoxymalonyl-CoA: 62.6
Methylmalonyl-CoA: 57.7
Propionyl-CoA: 36.8
Isobutyryl-CoA: 32.0
2-Methylbutyryl-CoA: 20.4
Ethylmalonyl-CoA: 18.3
Benzoyl-CoA: 15.9
Acetyl-CoA: 14.2
CHC-CoA: 11.0
trans-1,2-CPDA: 9.8
3-Methylbutyryl-CoA: 8.1
fatty_acid: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 100.0%; 2-Rhyd-Malonyl-CoA: 54.2%

ctg120_46

PKS_AT (568..864): mal

minowa: inactive

Prediction, score:

inactive: 205.7
Malonyl-CoA: 201.6
Methoxymalonyl-CoA: 56.6
Methylmalonyl-CoA: 51.5
Isobutyryl-CoA: 35.0
Propionyl-CoA: 30.6
Benzoyl-CoA: 16.9
Ethylmalonyl-CoA: 12.4
CHC-CoA: 10.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 100.0%; 2-Rhyd-Malonyl-CoA: 54.2%

c00127_3300027.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 1 - 11,670 nt. (total: 11,670 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 11670:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (beta-ala) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg127_2

PKS_AT (536..821): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 185.0
inactive: 130.7
Methoxymalonyl-CoA: 76.1
Methylmalonyl-CoA: 66.3
Propionyl-CoA: 50.4
Benzoyl-CoA: 40.7
Isobutyryl-CoA: 37.1
Ethylmalonyl-CoA: 35.7
2-Methylbutyryl-CoA: 21.8
CHC-CoA: 20.5
Acetyl-CoA: 16.2
trans-1,2-CPDA: 12.3
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 87.5%; 2-Rhyd-Malonyl-CoA: 54.2%

ctg127_3

Search NORINE for peptide: strict or relaxed

AMP-binding (475..797): beta-ala

NRPSPredictor2: beta-ala

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: VDAVFSvADK
Nearest Stachelhaus code:: beta-ala
Stachelhaus code match:: 90% (moderate)

c00132_3300027.. - Region 1 - T1PKS

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Location: 1 - 8,933 nt. (total: 8,933 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

Detailed domain annotation

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NRPS/PKS products

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Predicted core structure(s)

For candidate cluster 1, location 0 - 8933:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg132_2

PKS_AT (1087..1385): mal

minowa: inactive

Prediction, score:

inactive: 205.3
Malonyl-CoA: 202.5
Methoxymalonyl-CoA: 61.2
Methylmalonyl-CoA: 51.7
Propionyl-CoA: 32.4
Isobutyryl-CoA: 30.5
Benzoyl-CoA: 19.1
2-Methylbutyryl-CoA: 18.0
trans-1,2-CPDA: 15.5
Ethylmalonyl-CoA: 13.9
CHC-CoA: 11.6
Acetyl-CoA: 10.3
3-Methylbutyryl-CoA: 5.1
fatty_acid: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 95.8%; 2-Rhyd-Malonyl-CoA: 54.2%

c00134_3300027.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 5,603 - 49,424 nt. (total: 43,822 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

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NRPS/PKS products

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Predicted core structure(s)

For candidate cluster 1, location 5602 - 49424:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - pro) + (thr - ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg134_22

Search NORINE for peptide: strict or relaxed

AMP-binding (526..894): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: eVlHlSfgEK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 50% (weak)

CAL_domain (1110..1531): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 46.7
NH2: 26.2
Acetyl-CoA: 9.0
shikimic_acid: 0.0
AHBA: 0.0

AMP-binding (3231..3643): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAenIGAItK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

AMP-binding (4328..4732): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAqVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 90% (moderate)

ctg134_23

Search NORINE for peptide: strict or relaxed

AMP-binding (282..688): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

PKS_AT (1429..1723): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 168.2
inactive: 107.1
Methoxymalonyl-CoA: 66.1
Methylmalonyl-CoA: 45.4
Propionyl-CoA: 39.2
2-Methylbutyryl-CoA: 26.6
Ethylmalonyl-CoA: 21.3
Isobutyryl-CoA: 20.2
CHC-CoA: 19.3
Benzoyl-CoA: 15.6
Acetyl-CoA: 13.5
3-Methylbutyryl-CoA: 12.1
trans-1,2-CPDA: 9.5
fatty_acid: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; Methylmalonyl-CoA: 58.3%

c00139_3300027.. - Region 1 - terpene

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Location: 1 - 20,698 nt. (total: 20,698 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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c00143_3300027.. - Region 1 - T1PKS

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Location: 1 - 62,758 nt. (total: 62,758 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 62758:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ccmal) + (redmal - pk) + (ohmal) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg143_15

PKS_AT (599..897): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 196.4
inactive: 171.8
Methoxymalonyl-CoA: 60.4
Methylmalonyl-CoA: 53.3
Isobutyryl-CoA: 27.8
Propionyl-CoA: 25.6
Benzoyl-CoA: 20.4
2-Methylbutyryl-CoA: 15.6
Acetyl-CoA: 12.9
CHC-CoA: 11.8
Ethylmalonyl-CoA: 11.0
3-Methylbutyryl-CoA: 3.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 91.7%

ctg143_16

PKS_AT (579..875): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 219.6
inactive: 195.2
Methoxymalonyl-CoA: 70.2
Methylmalonyl-CoA: 67.9
Propionyl-CoA: 40.9
Isobutyryl-CoA: 34.7
Ethylmalonyl-CoA: 29.4
Benzoyl-CoA: 24.6
CHC-CoA: 24.4
2-Methylbutyryl-CoA: 22.9
Acetyl-CoA: 19.5
trans-1,2-CPDA: 13.1
3-Methylbutyryl-CoA: 10.7
fatty_acid: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 100.0%; 2-Rhyd-Malonyl-CoA: 54.2%

ctg143_17

PKS_AT (599..900): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 222.2
inactive: 202.4
Methylmalonyl-CoA: 61.9
Methoxymalonyl-CoA: 61.9
Propionyl-CoA: 44.9
Isobutyryl-CoA: 28.8
Benzoyl-CoA: 23.3
CHC-CoA: 19.4
Ethylmalonyl-CoA: 14.7
2-Methylbutyryl-CoA: 14.3
Acetyl-CoA: 11.6
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 100.0%; 2-Rhyd-Malonyl-CoA: 54.2%

PKS_AT (2776..2992): pk

minowa: inactive

Prediction, score:

inactive: 68.4
Malonyl-CoA: 60.0
Propionyl-CoA: 15.5
Methoxymalonyl-CoA: 14.9
Methylmalonyl-CoA: 13.1
Isobutyryl-CoA: 12.7
Benzoyl-CoA: 11.9
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: (unknown)

No matches above 50%

ctg143_18

PKS_AT (537..834): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 213.0
inactive: 201.4
Methoxymalonyl-CoA: 65.4
Methylmalonyl-CoA: 57.6
Propionyl-CoA: 35.0
Isobutyryl-CoA: 30.3
2-Methylbutyryl-CoA: 24.9
trans-1,2-CPDA: 16.7
Benzoyl-CoA: 15.7
Ethylmalonyl-CoA: 14.8
3-Methylbutyryl-CoA: 12.6
Acetyl-CoA: 10.5
CHC-CoA: 10.2
fatty_acid: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 100.0%; 2-Rhyd-Malonyl-CoA: 54.2%

ctg143_23

Search NORINE for peptide: strict or relaxed

AMP-binding (16..421): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: hiWcVGinCK
Nearest Stachelhaus code:: trp
Stachelhaus code match:: 50% (weak)

c00148_3300027.. - Region 1 - NRPS

Download region GenBank file

Location: 17,724 - 66,738 nt. (total: 49,015 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 17723 - 66738:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - ile - pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg148_29

Search NORINE for peptide: strict or relaxed

AMP-binding (15..419): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAiHvGLfnK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 60% (weak)

AMP-binding (1081..1482): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGlTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

AMP-binding (2148..2552): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFvAqVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 80% (moderate)

c00155_3300027.. - Region 1 - NRPS

Download region GenBank file

Location: 1 - 37,125 nt. (total: 37,125 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

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NRPS/PKS domains

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 37125:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg155_1

Search NORINE for peptide: strict or relaxed

AMP-binding (548..942): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DASTVAAVCK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

ctg155_5

Search NORINE for peptide: strict or relaxed

AMP-binding (528..975): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DarHFSLmvK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 60% (weak)

ctg155_8

Search NORINE for peptide: strict or relaxed

AMP-binding (340..751): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: glepLalAVK
Nearest Stachelhaus code:: pip
Stachelhaus code match:: 40% (weak)

c00156_3300027.. - Region 1 - NRPS-like

Download region GenBank file

Location: 5,662 - 33,954 nt. (total: 28,293 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

Detailed domain annotation

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Predicted core structure(s)

For candidate cluster 1, location 5661 - 33954:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg156_20

Search NORINE for peptide: strict or relaxed

AMP-binding (28..429): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGmVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

c00160_3300027.. - Region 1 - NRPS-like

Download region GenBank file

Location: 1 - 35,606 nt. (total: 35,606 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

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NRPS/PKS domains

Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 35606:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg160_9

Search NORINE for peptide: strict or relaxed

AMP-binding (30..431): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGvVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

c00162_3300027.. - Region 1 - cyanobactin

Download region GenBank file

Location: 42,213 - 54,420 nt. (total: 12,208 nt) Show pHMM detection rules used

Region on contig edge.

cyanobactin: cyanobactin_synth

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c00170_3300027.. - Region 1 - NRPS-like,T1PKS

Download region GenBank file

Location: 44,818 - 93,454 nt. (total: 48,637 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 44817 - 93454:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg170_52

CAL_domain (48..493): pk

minowa: NH2

Prediction, score:

NH2: 201.2
Acetyl-CoA: 49.2
fatty_acid: 22.4
AHBA: 8.8
shikimic_acid: 0.0

PKS_AT (1227..1534): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 213.8
inactive: 177.2
Methoxymalonyl-CoA: 75.6
Methylmalonyl-CoA: 67.6
Isobutyryl-CoA: 48.8
Propionyl-CoA: 47.2
Benzoyl-CoA: 33.6
2-Methylbutyryl-CoA: 29.3
Ethylmalonyl-CoA: 28.4
CHC-CoA: 24.1
Acetyl-CoA: 18.5
3-Methylbutyryl-CoA: 13.5
fatty_acid: 12.5
trans-1,2-CPDA: 12.2

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 91.7%; 2-Rhyd-Malonyl-CoA: 54.2%

c00173_3300027.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 2,695 - 78,633 nt. (total: 75,939 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 2694 - 78633:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal) + (val) + (ile - val) + (D-asn - phe) + (ohmal) + (leu - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg173_11

PKS_AT (563..860): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 204.5
inactive: 187.8
Methylmalonyl-CoA: 65.2
Methoxymalonyl-CoA: 64.7
Propionyl-CoA: 31.8
Ethylmalonyl-CoA: 27.1
Isobutyryl-CoA: 26.8
Benzoyl-CoA: 21.6
Acetyl-CoA: 15.7
trans-1,2-CPDA: 14.3
3-Methylbutyryl-CoA: 13.4
2-Methylbutyryl-CoA: 11.0
CHC-CoA: 9.4
fatty_acid: 0.0

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 100.0%; 2-Rhyd-Malonyl-CoA: 54.2%

ctg173_12

Search NORINE for peptide: strict or relaxed

AMP-binding (529..928): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

ctg173_13

Search NORINE for peptide: strict or relaxed

AMP-binding (542..942): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

AMP-binding (2023..2421): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

ctg173_14

Search NORINE for peptide: strict or relaxed

AMP-binding (541..938): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DATKiGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

AMP-binding (2072..2463): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAWTVAAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 100% (strong)

ctg173_15

PKS_AT (535..831): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 182.1
inactive: 110.2
Methoxymalonyl-CoA: 69.5
Methylmalonyl-CoA: 50.4
Propionyl-CoA: 41.1
Ethylmalonyl-CoA: 33.3
Isobutyryl-CoA: 26.2
2-Methylbutyryl-CoA: 23.7
CHC-CoA: 17.1
Benzoyl-CoA: 16.4
Acetyl-CoA: 13.7
3-Methylbutyryl-CoA: 9.2
trans-1,2-CPDA: 8.7
fatty_acid: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; Methylmalonyl-CoA: 58.3%

ctg173_16

Search NORINE for peptide: strict or relaxed

AMP-binding (543..939): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

AMP-binding (1615..2010): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAcFFGtVvK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)