LOCUS       c00165_3300027..        6418 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027641.a:Ga0208827_1003425.
ACCESSION   c00165_3300027..
VERSION     c00165_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 09:43:07
            Original ID  :: 3300027641.a:Ga0208827_1003425
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6418
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1482
                     /NRPS_PKS="Domain: CAL_domain (1-314). E-value: 6e-106.
                     Score: 346.3. Matches aSDomain:
                     nrpspksdomains_ctg165_1_CAL_domain.1"
                     /NRPS_PKS="Domain: PP-binding (419-483). E-value: 6.1e-11.
                     Score: 34.5. Matches aSDomain:
                     nrpspksdomains_ctg165_1_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 274;
                     E-value: 3.3e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg165_1"
                     /sec_met_domain="AMP-binding (E-value: 5.5e-72, bitscore:
                     231.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.4e-12, bitscore:
                     34.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="YVAFIQFSSGSTSEPKGVVLTHANLLANTRGATEIAHFNQDDVSL
                     SWMPLTHDMGLIGFHLMMLANRVHAHLMPTDLFVRRPLLWLQLAARIRATILCSPNFGY
                     RHYLKVLGERAPGELDLSRVRLIFNGAEPISVELCEQFLSRLAPTGLPRQAMFPVYGLA
                     EASLAVSFPEPGALYRATAFNRHQLGVGAEPQTIGVDEREAVRLASVGRAIPYCELRIA
                     GDDDQPMPAQRVGHIHIRGDNVTGGYYEDPAVNAATFTADGWLRTGDLGLIHQGELYIT
                     GRHKEILFVNGQNYYPYDLERIAEEVPGLELGKVVVAGVRPIGAQADELLVFVLHRADM
                     AGFVPLARQVAARIGEHAGVEVSAVVPVRRIPKTTSGKFQRHLLEQEYLAGAFTGELAE
                     LERLRAHEPAARVDGSEITQLLRGICEQELEGRSIDVDESLFDVGTSSLKLIAIHERIE
                     RLWPGLVDVTDIFDHPSIAALARFLEQKLAAGSRS"
     protocluster    1..6418
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:1482](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..1482
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..6418
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6418
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     aSDomain        4..942
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg165_1_CAL_domain.1"
                     /evalue="6.00E-106"
                     /label="ctg165_1_CAL_domain.1"
                     /locus_tag="ctg165_1"
                     /protein_end="314"
                     /protein_start="1"
                     /score="346.3"
                     /specificity="Minowa: fatty_acid"
                     /tool="antismash"
                     /translation="VAFIQFSSGSTSEPKGVVLTHANLLANTRGATEIAHFNQDDVSLS
                     WMPLTHDMGLIGFHLMMLANRVHAHLMPTDLFVRRPLLWLQLAARIRATILCSPNFGYR
                     HYLKVLGERAPGELDLSRVRLIFNGAEPISVELCEQFLSRLAPTGLPRQAMFPVYGLAE
                     ASLAVSFPEPGALYRATAFNRHQLGVGAEPQTIGVDEREAVRLASVGRAIPYCELRIAG
                     DDDQPMPAQRVGHIHIRGDNVTGGYYEDPAVNAATFTADGWLRTGDLGLIHQGELYITG
                     RHKEILFVNGQNYYPYDLERIAEEVPGLELGKV"
     aSModule        4..1449
                     /domains="nrpspksdomains_ctg165_1_CAL_domain.1"
                     /domains="nrpspksdomains_ctg165_1_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg165_1"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       7..66
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg165_1_0001"
                     /evalue="3.50E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg165_1"
                     /protein_end="22"
                     /protein_start="2"
                     /score="22.6"
                     /tool="antismash"
                     /translation="AFIQFSSGSTSEPKGVVLTHA"
     CDS_motif       697..777
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg165_1_0002"
                     /evalue="4.50E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg165_1"
                     /protein_end="259"
                     /protein_start="232"
                     /score="19.1"
                     /tool="antismash"
                     /translation="RVGHIHIRGDNVTGGYYEDPAVNAATFT"
     aSDomain        1258..1449
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg165_1_PP-binding.1"
                     /evalue="6.10E-11"
                     /label="ctg165_1_PP-binding.1"
                     /locus_tag="ctg165_1"
                     /protein_end="483"
                     /protein_start="419"
                     /score="34.5"
                     /tool="antismash"
                     /translation="LLRGICEQELEGRSIDVDESLFDVGTSSLKLIAIHERIERLWPGL
                     VDVTDIFDHPSIAALARFLE"
     CDS             1492..2889
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 348.3; E-value: 1.2e-105)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg165_2"
                     /sec_met_domain="Trp_halogenase (E-value: 3.7e-22,
                     bitscore: 67.6, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIMYHDISRLLESDPMMDRGSPDAAASTGDAALQQTDVLVIGGG
                     PAGSTVATLLARRGHHVTLVEKDRHPRFHIGESLLPANLPLFEQLGIAEQVRAIGMQKW
                     GAEFISHWDGRHQDFRFAEAWDKSMPYAYQVRRSQFDEILIRNAVHAGAQVIEGCRVRT
                     VEFQRDHGSTGVGIVRIEARHQDGRTRRWQARYLIDASGRDTFLANHFGVKRRNPKHNS
                     AAIFGHFSGAERYAGDRAGHISIYWFDHGWFWFIPLHDGATSVGAVVWPYYLKSRSVPV
                     HEFFLATIALCPPLAQRLANATLTTEVEATGNYSYSSTRSHGEGYLLLGDAYAFIDPVF
                     SSGVMLAMNSAFVGADAVDACLRAPARARAALREFDRSMRSGPREFSWFIYRVTTPAMR
                     EMLLAPRNLLRMKEALLSLLAGDIFGSTPIWKSVRAFKMTYRLSSLLHPRRSARAARRH
                     SINIRPV"
     misc_feature    1525..1527
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             2912..3958
                     /locus_tag="ctg165_3"
                     /transl_table=11
                     /translation="MAVAAALQVDYVRFSDMRQRPAAWWQDVLAVIRFDGGAPSAPLAG
                     MPLTEVNAPVLAGADGANSVAEVWRLAGPMHSGQRGRVRYRHNGRLLFASLSIYEAEFA
                     DGPACGAATALHRATDAGYREMFGALETLAFPYPLRIWNFLSEINATSDDGERYWHFNS
                     ARQDVFIGLNRAIAGNVPAASAVGVGPASPLTIYCIASARAPIALENPRQCSAWDYPAQ
                     YGPRSPTFARACIASDAAQTLFISGTASIVGHASAHAGDQREQTREIVRNIRALIGAAN
                     DHLGGERYQLERLRYKVYVRHAEHQPSIDRELRHEVGAAAQVLYLKADICRHDLLVEIE
                     AVSTPEPL"
     CDS             4099..4824
                     /locus_tag="ctg165_4"
                     /transl_table=11
                     /translation="VVFNDYRGASSVHGYPVPVPYFLYRGNILRADRDGLHGRFLDQRY
                     LEFDISLNATAPVFSRSSAPRAGMPNLDPTLELGPSLQWHLWRGVDERLRLDLRTPVRN
                     AITVASPPRSIGWVFAPNLSLDYRAVGRAAGWNLGLLAGPLYAQRRYDEYFYAVAPQYA
                     TPTRPTYEPPGGYGGTQLLVAASKRYANYWIGAYLRHDWLQRAVFLDSPLVQQRSYWSG
                     GFGIVWMISASSRMVDSDD"
     CDS             4817..5629
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 76.7; E-value: 3.6e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg165_5"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.9e-22,
                     bitscore: 66.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETRAIGVTTDRRADVPLTTPSATHLVLIPSYNPGPRVFETVIA
                     ARAQWNPVWVVVDGSTDGSATALAAMAQRDPGLRVLALPRNRGKGSAVVHGARAAQAAG
                     YTHILTMDSDGQHPADLIGRFMAASLAEPTALILGEPQFDASAPALRVQGRKLSNFWAN
                     VETLWAGIHDSLFGFRVYPVEPLLRVMRYQPWMRRFDFDAEVAVRLCWRGLRPRNIRAP
                     VRYFRPEEGGVSHFNYWRDNALLTWMHMRLFAGFWLRLPLLAWRRLRG"
     CDS             5743..6045
                     /NRPS_PKS="Domain: PP-binding (26-79). E-value: 2.1e-10.
                     Score: 32.7. Matches aSDomain:
                     nrpspksdomains_ctg165_6_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg165_6"
                     /sec_met_domain="PP-binding (E-value: 2.9e-11, bitscore:
                     32.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSERALPTQTTPQIDALALESEIAQLIVKGLNLPMQPDEIDPEAP
                     LYGEGLGLDSIDILEIALIVSKQYGVQLRADNQENARIFRSLRHFAQYVAEQRVK"
     aSDomain        5821..5979
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg165_6_PP-binding.1"
                     /evalue="2.10E-10"
                     /label="ctg165_6_PP-binding.1"
                     /locus_tag="ctg165_6"
                     /protein_end="79"
                     /protein_start="26"
                     /score="32.7"
                     /tool="antismash"
                     /translation="IVKGLNLPMQPDEIDPEAPLYGEGLGLDSIDILEIALIVSKQYGV
                     QLRADNQEN"
     aSModule        5821..5979
                     /domains="nrpspksdomains_ctg165_6_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg165_6"
                     /tool="antismash"
                     /type="unknown"
     CDS             6137..6418
                     /locus_tag="ctg165_7"
                     /transl_table=11
                     /translation="MSALPLIAHDRPAAVIAYRRGLAITAAQFLDDVRALAARLPAGAH
                     VLNFCGERYRFAVGLAASLVSGKCSILPSTHTPEVIRHLRAFAPDVFCL"
ORIGIN
        1 tatgtcgcct tcatccagtt ctcctccggc tcgaccagcg agcccaaagg cgtagtgctc
       61 acgcacgcga acctgctggc gaatacccgc ggcgccaccg agatcgcgca tttcaaccag
      121 gacgacgtca gcctgtcatg gatgccgctg acgcacgaca tgggtctgat cggctttcat
      181 ctgatgatgc tcgccaatcg cgtccatgcc catctgatgc cgaccgatct gttcgttcgc
      241 cgaccgctgc tgtggctgca gctcgccgcg cgcatacgcg ccaccattct gtgttcgccg
      301 aatttcggct accgccacta cctcaaggtg ctgggcgaac gcgctccggg cgaactcgac
      361 ctgtcgaggg tacggctcat cttcaatggc gccgagccga tcagcgtcga gctgtgcgag
      421 cagtttctga gccggctggc gcccacaggc ctgccgcgcc aggccatgtt tcccgtttac
      481 ggcctcgccg aagcctcgct ggccgtgagc tttcccgagc cgggtgcgct ctatcgtgcg
      541 accgccttca accgccatca gctcggtgtc ggcgcggaac cgcaaacgat cggggtcgac
      601 gagcgcgagg ccgtgaggct cgcgagcgta gggcgcgcga tcccctattg cgagctgcgc
      661 atcgccggtg acgacgacca gcccatgccc gcgcagcgcg tcggccacat ccatattcgc
      721 ggcgacaatg tcaccggcgg ctattacgag gatccggcag ttaacgctgc aacttttaca
      781 gccgacggct ggctgcgaac cggcgacctg ggattgatcc atcagggcga gctctatatc
      841 accggtcgcc acaaggaaat cctgttcgtc aatggccaga actactaccc ctacgacctg
      901 gagcgcatcg ccgaggaggt gccgggcctc gagctcggca aggtagtggt cgcgggcgtg
      961 cgtccgatcg gcgcccaggc cgacgagttg ctggtatttg tgctccatcg cgctgacatg
     1021 gccgggttcg tgccgctcgc gcgccaggtc gcggcccgca tcggtgagca cgcgggagtc
     1081 gaggtcagcg ccgtggtgcc ggtgcggcgc atccccaaga ccaccagcgg caagtttcaa
     1141 cggcatctgc tcgaacagga atatctcgcc ggcgccttca ctggggaact tgccgaactg
     1201 gagcggctgc gcgcccatga acccgcagcg cgcgtcgacg gcagtgaaat cacgcaactc
     1261 ctgcgcggca tctgcgagca ggagctcgaa ggccgcagca tcgacgtcga tgagagtctg
     1321 ttcgacgtcg gcaccagctc gctgaagttg atcgcaatcc acgaacgcat cgagcgcctg
     1381 tggccgggcc tggtcgatgt caccgatatc ttcgatcacc cgagcattgc cgcgctggcg
     1441 cgcttcctcg aacagaagct ggccgccgga tcgcgctcgt gaccgcgccc gatggccatt
     1501 atgtaccacg acatttcccg gctgttagaa tccgacccca tgatggatcg cggatcgccc
     1561 gatgccgcag cgtcgaccgg cgacgcagcg ttgcagcaaa cggatgtgct ggtgatcggc
     1621 gggggtccgg cgggttctac cgttgcgacc ctgctcgcac gccgtggcca ccacgtcacc
     1681 ctggtcgaga aagaccgcca cccgcgcttc catattggcg agtcgctgct gcccgctaac
     1741 ctgccgctgt tcgagcagct cggcatcgcc gagcaggtgc gcgccatcgg catgcagaaa
     1801 tggggcgccg aattcatctc ccactgggac gggcggcacc aggacttccg cttcgcggag
     1861 gcctgggaca aatcaatgcc gtacgcgtac caggtgcggc gttcgcaatt cgatgagatc
     1921 ctgattcgca acgccgtgca cgcgggcgca caggtcatcg aaggctgtcg cgtgcgcacc
     1981 gtcgagttcc agcgcgacca cggcagcacc ggtgttggca ttgttcggat cgaggcacgg
     2041 caccaggacg gccgcacgcg gcgctggcag gctcgctatc tgatcgatgc gtcgggtcgc
     2101 gacacatttc tggccaacca ctttggtgtc aagcgccgca atcccaagca taacagcgcg
     2161 gccatcttcg gccatttcag cggcgccgag cgctacgccg gcgaccgcgc gggccacatc
     2221 tctatttact ggttcgatca cggctggttc tggttcattc cgctgcacga tggcgcgacc
     2281 agcgtcggcg ccgtggtctg gccctactac ctcaaatcgc gctcggtgcc ggtccatgaa
     2341 ttctttctgg cgactatcgc gctgtgtccg ccgctcgcgc agcgtcttgc caacgccaca
     2401 ctgaccaccg aggtcgaggc caccggcaac tactcgtaca gctcgacgcg cagccacggc
     2461 gagggctatc tactactcgg cgatgcctat gccttcatcg acccggtgtt ctcctcggga
     2521 gtgatgctgg cgatgaacag cgccttcgtc ggcgccgacg ccgtcgatgc ctgcttgcgt
     2581 gcacccgcgc gcgcccgcgc ggcgctgcgc gagttcgacc ggtcgatgcg ctcgggtccg
     2641 cgcgagttct cgtggttcat ctatcgggtc accacgccgg cgatgcgcga aatgttgctg
     2701 gccccgcgta atctcctgcg catgaaggag gcgctgctct cgctgctggc cggggacatc
     2761 tttggcagca cgccgatctg gaagtcggta cgtgccttca aaatgacgta ccggttgtcc
     2821 tcgctgctgc atccacgccg cagcgcgcgg gccgcgcggc gtcacagcat caacattcgg
     2881 ccggtctgaa gcggcgatgc tcgagcaatt gatggctgtg gctgcggccc tacaagtcga
     2941 ttacgtacgc ttcagcgaca tgcgccaacg cccggcggcg tggtggcagg atgtgctcgc
     3001 agtgatccgc ttcgatggcg gcgcaccctc ggcgccgctc gccgggatgc cattgaccga
     3061 ggtcaacgcg ccggtgctcg ccggtgccga cggtgccaac agcgtcgcgg aagtctggcg
     3121 tctcgccggg ccgatgcact ccggtcagcg cgggcgagtc cgctatcgcc acaacggccg
     3181 actgctgttc gcgagcctga gcatttatga agcagagttc gccgacggtc cagcgtgtgg
     3241 cgcagccact gcgctgcatc gcgcgaccga cgcgggctac cgcgaaatgt tcggcgcgct
     3301 cgagacgctg gcctttcctt acccgctgcg gatctggaac tttctatccg agatcaatgc
     3361 caccagcgac gatggcgaac gctactggca cttcaacagc gcgcgccagg acgttttcat
     3421 cggcttgaat cgcgccatcg ccggcaacgt gccggccgcg agcgccgtgg gcgtggggcc
     3481 ggccagcccg ctgaccatct actgcatcgc cagcgcacga gcgccgattg cgctcgagaa
     3541 tccgcgccag tgcagcgcct gggattaccc ggcgcagtac ggcccgcgca gcccgacttt
     3601 cgcccgcgcc tgcatcgcga gcgatgcggc gcagaccttg ttcatttccg gtaccgccag
     3661 cattgtcggc cacgcgagcg cgcatgccgg cgatcagcgc gagcagacgc gcgagatcgt
     3721 gcgcaatatt cgcgccctga tcggcgctgc caatgatcac ctcggcggcg agcgctacca
     3781 gctcgagcgt ctacgctata aagtctatgt gcggcatgcc gagcaccaac cgagcatcga
     3841 tcgggaactg cggcatgaag tcggcgctgc ggcacaggtg ctatacctga aggcggatat
     3901 ctgccggcac gacctgctgg tcgagatcga agcggtcagc acgccggagc cgctctgagc
     3961 agccggcgtc gccgccaggg gtgcgctcgc cgcgcgccgc gcaccgcgct tgcggcgctg
     4021 acgctgggtg cgctgctcgc cgacaacgcg cacgccagcg accagccgct gtgggaattg
     4081 ggcttaggtg taggcggcgt ggtcttcaac gactatcgtg gcgcgtcgag cgtgcacggc
     4141 tatccggtac cggtgcccta cttcctctat cgcggcaata tcctgcgcgc cgaccgcgac
     4201 ggcctgcatg gccgctttct cgatcagcgc tatctggaat tcgacatcag cctcaatgcc
     4261 acggcgccgg tgttcagccg cagcagcgcc ccgcgcgcgg gcatgcccaa tctcgatccg
     4321 acgctcgaac tcggcccctc gctgcagtgg catctgtggc gcggcgtcga tgagcggctg
     4381 cggcttgatt tgcgcacgcc cgtccgcaat gccatcaccg ttgcctcgcc gccgcgttcg
     4441 atcggctggg tgttcgcgcc gaatctcagc ctcgattacc gcgccgtcgg gcgcgcggcc
     4501 ggctggaacc tgggtctgct cgccgggccg ctgtatgccc agcgtcgcta tgacgagtat
     4561 ttttacgcgg tggcgccgca gtacgcgacg ccgacccggc caacctatga accgccgggc
     4621 ggctacggcg gcacgcagct gctggttgcg gccagcaaac gctacgcgaa ctactggatc
     4681 ggcgcctatt tgcgccatga ttggctgcag cgagcggtct ttctcgacag tccgctggtg
     4741 cagcaacgca gctattggtc gggcggattc ggtatcgtgt ggatgatcag cgcctcttcc
     4801 aggatggtcg acagcgatga ctgaaacgcg cgccatcggc gtcaccacgg atcggcgagc
     4861 cgacgtgcca ctgactacgc cctcggccac gcacctggtg ctgatcccca gctacaaccc
     4921 gggacccagg gtattcgaga ccgtgattgc ggcgcgcgcg cagtggaatc cggtctgggt
     4981 ggtggtcgat ggcagtaccg acggcagcgc gacggccctc gcagccatgg cgcaacgcga
     5041 cccgggactg cgcgtgctgg cgctgccgcg caatcgcggc aagggctcgg ccgtcgttca
     5101 cggcgcgcgc gccgcccagg ccgcgggcta tacccatatc cttaccatgg attccgacgg
     5161 ccaacatccg gctgacctta tcggccgctt catggccgcg tcgctggcgg aacccaccgc
     5221 actgattctg ggtgagccac agttcgatgc cagcgcccct gcgctgcggg tgcaaggccg
     5281 caagctctcg aacttctggg ccaacgtcga gaccctatgg gccggcatcc acgactccct
     5341 gttcggattt cgggtctatc ccgtcgagcc gctgctgcgg gtcatgcgct accagccgtg
     5401 gatgcgccgc ttcgacttcg acgccgaggt cgccgtgcgc ctgtgctggc gcgggctacg
     5461 gccgcgcaat atccgggcgc cggtgcggta tttccgcccg gaagaaggcg gcgtctcgca
     5521 cttcaattac tggcgtgaca atgcgctgct gacctggatg catatgcgcc tttttgcagg
     5581 cttttggctg cgcctgccgc tgctggcgtg gcggcgcctg cggggttgaa actcgctcgc
     5641 gccgatggca atcccgatat aatgcgcgcc gattcggctg gaccagcagt gcaccggcct
     5701 tggcatttaa ggcctttccg gactggagat aaccacccca ttatgtccga acgagcgttg
     5761 cccacacaga cgactccgca gatcgatgcg ctcgcgctgg agagcgagat cgcgcagctg
     5821 atcgtcaagg gacttaatct accgatgcag ccggatgaga tcgatcccga agcccccctc
     5881 tacggtgagg gactcgggct cgactccatc gacatcctcg agatcgcact cattgtctcg
     5941 aagcagtacg gcgttcagtt gcgtgccgac aatcaggaga atgcgcgcat ctttcgttca
     6001 ttgcggcatt tcgcccaata cgtggccgag cagagagtca agtgacacgc gactggctgc
     6061 aacggcgtct gatcgcggcc tccaccgcca cccgcactga aacggcgccg cgctgctgag
     6121 gcatcgctga cagcgtatgt ccgcgttgcc tctcatcgcg cacgatcggc ccgctgccgt
     6181 cattgcctat cgccgcgggc tggcgattac cgcggctcaa ttcctcgacg atgtgcgcgc
     6241 gctggcggcg cgattgcccg cgggcgcgca tgtgctcaat ttctgcggcg agcgttatcg
     6301 cttcgccgta gggctcgcgg ccagcctggt gagtggcaag tgcagcatct tgccgtcgac
     6361 gcataccccg gaggttatcc gacacctgcg cgcgttcgcg ccggacgtgt tctgtctc
//
