LOCUS       c00345_3300027..        3739 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027673.a:Ga0209278_1012478.
ACCESSION   c00345_3300027..
VERSION     c00345_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 21:06:22
            Original ID  :: 3300027673.a:Ga0209278_1012478
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3739
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..3585)
                     /NRPS_PKS="Domain: AMP-binding (53-454). E-value: 9.4e-110.
                     Score: 358.7. Matches aSDomain:
                     nrpspksdomains_ctg345_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (563-631). E-value: 2.5e-22. Score:
                     70.6. Matches aSDomain: nrpspksdomains_ctg345_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (661-959). E-value:
                     2.3e-90. Score: 294.3. Matches aSDomain:
                     nrpspksdomains_ctg345_1_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     393.3; E-value: 2.7e-119)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg345_1"
                     /sec_met_domain="Condensation (E-value: 1.6e-73, bitscore:
                     234.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-120, bitscore:
                     389.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.7e-16, bitscore:
                     45.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGALRRWNAAPAAHRFPRPNAAGAASGSKWSPVVNPCSLESVP
                     YPTLLHRVFETHAARAPDAHALATRDATVSYDALNVAANRLARHLRMCGVAPDALVAIC
                     MQRTPTLFEAVLAVLKAGGAYVPLDPNYPEERLAQMLSDARPSVVLTDAASADALRAAM
                     TRAGRTATTIDVGVECETWSSQSSENLSSDDAGLTPQHLAYVIYTSGSTGTPKGVMIEH
                     GGLTHLLQAQTATFDVDADARVLQFASFSFDACVFEWVMAFGHGACLCLGAPGMPPIGD
                     ALVAAIDAHRITHATIPPVALSTLPHDAALPSLRVLISAGEALPPVLMRRWSRGRRMFN
                     AYGPTETTVWCTVHACDPDAEDASVPIGCAIPGATAYALDEHRRPVADGELGELYVGGA
                     GLARGYLHRPELTAERFVDQARDGERLYRTGDVVRRRPDGALEYHGRNDSQVKIRGFRI
                     ELGEIESALTRLNGIEEAAVVARDDDSGPPRLIAYVLATADRDVTAQTLRATLAGRLPD
                     YMVPAAYVRMTAWPQTPNGKLDRRALPAPRPEDFASAAYVEPEGDTETALAAIWCELLA
                     IERVGRDDRFLDLGGNSLKTIQLATRIRACFGREMPVDALFKAPSLRTMAAAIDAQPTH
                     AGLDVDAGAFDAWNDAAPDALADPVRDPVSYQQHGLWLLEQVTKTSLAYNAQNVIRIRG
                     EIDPELLQRAVDCVIERHEIFRTTFHDDGSGQQYQRVHPSAPGVLQTQALSDDADEAAL
                     QATIDAHVAYRFDLTRLPLVRLTLIRRGPADYVLIHVEQHYVHDGWSANLFMREMLDAY
                     AAYARGETPALPPVPAQYRDYARWQRSEGAKARYAKHLAFWTAQVADVPHTLALPTDRP
                     RPDEPSYAGTQLRCELPPEMASALRRFCAAEGFTLYAAMHAVYQIVLRAAGGTDTFLIG
                     SAVANRRSRKSEGMLGMFVNMIPIRADVSGNPSYRELLDRTTATLSASYEHEELPFEWL
                     VRAVRPERTTGHNPLFQTAFSAHNSDLPNLRRSGFELSMFEAYSNRTSKFDFDVVMLPR
                     GQAHADSVTLLWNFATDLFETATIERLRDAYLRVLAQCLADPDRRLQTIETMAPDDRAR
                     LLEGGYREAPFDTAYCLHHAFEAHADRAPDAHALATRDATVNYGALNADANRLARHLRG
                     CGVGPDALVAICMQRTPALFEAVLAVLKA"
     protocluster    1..3739
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3585](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1..3585)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3739
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3739
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS_motif       complement(556..669)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg345_1_0009"
                     /evalue="1.70E-17"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg345_1"
                     /protein_end="1010"
                     /protein_start="972"
                     /score="55.8"
                     /tool="antismash"
                     /translation="ATLSASYEHEELPFEWLVRAVRPERTTGHNPLFQTAFSA"
     aSDomain        complement(709..1602)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg345_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.30E-90"
                     /label="ctg345_1_Condensation_LCL.1"
                     /locus_tag="ctg345_1"
                     /protein_end="959"
                     /protein_start="661"
                     /score="294.3"
                     /tool="antismash"
                     /translation="DPVSYQQHGLWLLEQVTKTSLAYNAQNVIRIRGEIDPELLQRAVD
                     CVIERHEIFRTTFHDDGSGQQYQRVHPSAPGVLQTQALSDDADEAALQATIDAHVAYRF
                     DLTRLPLVRLTLIRRGPADYVLIHVEQHYVHDGWSANLFMREMLDAYAAYARGETPALP
                     PVPAQYRDYARWQRSEGAKARYAKHLAFWTAQVADVPHTLALPTDRPRPDEPSYAGTQL
                     RCELPPEMASALRRFCAAEGFTLYAAMHAVYQIVLRAAGGTDTFLIGSAVANRRSRKSE
                     GMLGMFVNMIPIRADVSG"
     aSModule        709..1602
                     /domains="nrpspksdomains_ctg345_1_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg345_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(721..807)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg345_1_0008"
                     /evalue="3.10E-10"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg345_1"
                     /protein_end="955"
                     /protein_start="926"
                     /score="32.5"
                     /tool="antismash"
                     /translation="FLIGSAVANRRSRKSEGMLGMFVNMIPIRA"
     CDS_motif       complement(1069..1101)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg345_1_0007"
                     /evalue="1.60E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg345_1"
                     /protein_end="839"
                     /protein_start="828"
                     /score="14.3"
                     /tool="antismash"
                     /translation="QYRDYARWQRSE"
     CDS_motif       complement(1150..1209)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg345_1_0006"
                     /evalue="1.70E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg345_1"
                     /protein_end="812"
                     /protein_start="792"
                     /score="17.5"
                     /tool="antismash"
                     /translation="HYVHDGWSANLFMREMLDAYA"
     CDS_motif       complement(1426..1539)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg345_1_0005"
                     /evalue="1.80E-17"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg345_1"
                     /protein_end="720"
                     /protein_start="682"
                     /score="55.6"
                     /tool="antismash"
                     /translation="AYNAQNVIRIRGEIDPELLQRAVDCVIERHEIFRTTFHD"
     aSDomain        complement(1693..1896)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg345_1_PCP.1"
                     /evalue="2.50E-22"
                     /label="ctg345_1_PCP.1"
                     /locus_tag="ctg345_1"
                     /protein_end="631"
                     /protein_start="563"
                     /score="70.6"
                     /tool="antismash"
                     /translation="ETALAAIWCELLAIERVGRDDRFLDLGGNSLKTIQLATRIRACFG
                     REMPVDALFKAPSLRTMAAAIDAQ"
     aSModule        1693..3426
                     /complete
                     /domains="nrpspksdomains_ctg345_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg345_1_PCP.1"
                     /locus_tags="ctg345_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     misc_feature    complement(2101..2103)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       complement(2194..2259)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg345_1_0004"
                     /evalue="4.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg345_1"
                     /protein_end="464"
                     /protein_start="442"
                     /score="37.8"
                     /tool="antismash"
                     /translation="YHGRNDSQVKIRGFRIELGEIES"
     aSDomain        complement(2224..3426)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg345_1_AMP-binding.1"
                     /evalue="9.40E-110"
                     /label="ctg345_1_AMP-binding.1"
                     /locus_tag="ctg345_1"
                     /protein_end="454"
                     /protein_start="53"
                     /score="358.7"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FETHAARAPDAHALATRDATVSYDALNVAANRLARHLRMCGVAPD
                     ALVAICMQRTPTLFEAVLAVLKAGGAYVPLDPNYPEERLAQMLSDARPSVVLTDAASAD
                     ALRAAMTRAGRTATTIDVGVECETWSSQSSENLSSDDAGLTPQHLAYVIYTSGSTGTPK
                     GVMIEHGGLTHLLQAQTATFDVDADARVLQFASFSFDACVFEWVMAFGHGACLCLGAPG
                     MPPIGDALVAAIDAHRITHATIPPVALSTLPHDAALPSLRVLISAGEALPPVLMRRWSR
                     GRRMFNAYGPTETTVWCTVHACDPDAEDASVPIGCAIPGATAYALDEHRRPVADGELGE
                     LYVGGAGLARGYLHRPELTAERFVDQARDGERLYRTGDVVRRRPDGALEYHGRNDSQVK
                     IRG"
     CDS_motif       complement(2338..2424)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg345_1_0003"
                     /evalue="2.40E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg345_1"
                     /protein_end="416"
                     /protein_start="387"
                     /score="51.8"
                     /tool="antismash"
                     /translation="DGELGELYVGGAGLARGYLHRPELTAERFV"
     CDS_motif       complement(2920..2979)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg345_1_0002"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg345_1"
                     /protein_end="222"
                     /protein_start="202"
                     /score="36.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVMIEHG"
     CDS_motif       complement(3199..3240)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg345_1_0001"
                     /evalue="2.30E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg345_1"
                     /protein_end="129"
                     /protein_start="115"
                     /score="20.5"
                     /tool="antismash"
                     /translation="LAVLKAGGAYVPLDP"
     CDS             complement(3646..3738)
                     /locus_tag="ctg345_2"
                     /transl_table=11
                     /translation="EAMLDESVQDDAMHAEGAPDVSAEDTEAVV"
ORIGIN
        1 cgctttcaac accgccagca ccgcctcgaa caaggccggc gtgcgctgca tgcagatcgc
       61 caccaacgca tccggcccca cgccgcaccc gcgcagatgc cgcgccagac gattcgcgtc
      121 ggcgttcagc gcgccgtagt tcacggtcgc gtcgcgcgtc gccagcgcat gcgcgtcggg
      181 cgcacgatcg gcgtgggctt cgaacgcatg atgcagacaa tacgccgtgt cgaacggcgc
      241 ttcgcgatag ccgccttcca gcaagcgcgc gcggtcgtcc ggcgccatgg tttcgatggt
      301 ctgcaggcgt cgatcaggat cggcgagaca ttgcgccaag acgcgcaaat acgcatcgcg
      361 caggcgctcg atcgtcgccg tctcgaacaa gtcggtcgcg aaattccaca gcaacgtcac
      421 gctatcggca tgcgcttgac cgcgcggcag catcaccacg tcgaaatcga acttcgatgt
      481 gcggttgcta taggcctcga acatcgacag ctcgaaaccc gagcgacgca ggttcggaag
      541 atcggagttg tgcgcgctga acgcggtttg gaacaagggg ttatgcccgg tcgtgcgctc
      601 cggccgcacc gcacgcacca gccattcgaa cggcagttcc tcgtgctcgt aggacgccga
      661 caacgtggcg gtggtgcgat cgagcagttc gcgatagctg ggattgcccg aaacgtcggc
      721 gcggatcgga atcatgttca cgaacatgcc gagcatgcct tcggacttgc gcgaacgccg
      781 attcgcgacc gccgaaccga tcaagaacgt gtccgtgccg cctgcggcgc gcaatacgat
      841 ctggtagacc gcatgcatcg ccgcgtagag cgtaaaacct tccgctgcgc agaaccgtcg
      901 caacgccgac gccatttcgg gcggcaattc gcagcgcaat tgcgtgccgg cgtacgaggg
      961 ttcgtcggga cggggacgat cggtcggcag cgccagcgtg tgcggcacat cggccacttg
     1021 cgcggtccag aacgcgagat gtttcgcgta gcgcgccttc gcgccttcgc tgcgctgcca
     1081 acgcgcgtag tcgcgatatt gcgcgggtac cggcggcagc gcgggcgttt ctcctcgcgc
     1141 ataggccgcg tacgcatcca gcatttcgcg catgaacaga ttcgcgctcc aaccgtcgtg
     1201 gacataatgc tgttcgacgt ggatcaacac gtaatcggcg gggccgcgac gaatcagagt
     1261 caagcgcacc aacggcagtc gcgtcagatc gaaacgatac gccacatgcg cgtcgatcgt
     1321 ggcctgcagc gcggcttcgt cggcatcgtc gctcagcgct tgcgtttgca gcacacccgg
     1381 cgcggacgga tgcacgcgct ggtattgctg acccgaaccg tcgtcgtgga acgtcgttcg
     1441 gaaaatttcg tggcgctcaa tgacgcagtc gaccgcgcgt tgcagcagtt cgggatcgat
     1501 ctcgccgcga atgcggatca cgttctgcgc gttgtaggcc aacgatgtct tggtgacttg
     1561 ttccagcaac caaaggccgt gctgttggta ggagacggga tcgcgcaccg gatcggcgag
     1621 cgcgtcgggc gctgcgtcgt tccaggcatc gaacgcaccc gcatcgacat cgagccccgc
     1681 atgcgtcggc tgcgcgtcga tcgccgccgc catcgtccgc aagctcggcg ccttgaacag
     1741 cgcatcgacc ggcatctcgc ggccgaaaca cgcgcgaatc cgcgtcgcca attgaatggt
     1801 tttcagcgaa tttccgccca aatcgagaaa acgatcgtcg cggcccacgc gctcgatcgc
     1861 cagcagctcg caccagatcg ccgccaaggc ggtttcggta tcgccctcgg gctcgacgta
     1921 agccgcgctc gcgaaatctt cgggccgcgg cgccggcaac gcgcgccgat cgagtttgcc
     1981 gttcggggtc tgcggccatg cggtcatgcg gacgtaggcg gcgggcacca tgtaatccgg
     2041 caatcggccg gcgagcgtcg cgcgcagcgt ttgcgccgtc acatcgcggt cggcggtcgc
     2101 taacacatac gcgatcaacc gcggcggtcc gctgtcgtcg tcgcgcgcga cgacagcggc
     2161 ttcttcgatg ccattcagtc gcgtcaacgc ggattctatt tcgcccagtt cgatccggaa
     2221 accgcggatt ttcacttgcg aatcgttacg gccgtggtat tcgagcgcgc cgtcgggccg
     2281 acgacgcacc acatccccgg tgcgatagag acgttcgcca tcgcgcgcct ggtcgacgaa
     2341 acgctccgcc gtcaattccg gccgatgcaa atacccgcgc gccaaacccg cgccgccgac
     2401 gtacagctca ccgagttcgc cgtcggcgac cggacggcgg tgctcgtcga gcgcgtacgc
     2461 ggtcgcgccg ggaatcgcgc atccgatcgg cacgctcgcg tcttccgcat ccgggtcgca
     2521 ggcatggacc gtacaccaga ccgtggtttc ggtcggtccg taggcgttga acatccgccg
     2581 gccgcgcgac caacgccgca tcagcacagg cggcaacgct tcgcccgcgg aaatcagcac
     2641 gcgcaacgaa ggcaaggcgg catcgtgcgg cagcgtcgac agcgctaccg gcggaatcgt
     2701 cgcgtgggta atgcgatgcg cgtcgatcgc cgcgaccaaa gcatcgccga tcggcggcat
     2761 gcccggcgcc cccaaacaca gacaggcgcc atgaccgaag gccatgaccc actcgaacac
     2821 gcaggcatcg aaactgaagg acgcgaattg cagcacgcgc gcatccgcat ccacatcgaa
     2881 ggtcgcggtc tgcgcctgca acagatgcgt caagccgccg tgctcgatca ttacgccctt
     2941 cggcgttccg gtcgatcccg acgtgtagat cacgtacgcc aaatgctgcg gggtcagacc
     3001 cgcgtcgtcg ctcgagagat tctccgatga ctgcgacgac caggtttcgc attcgacgcc
     3061 gacatcgatc gtcgtcgccg tgcgacccgc gcgtgtcatc gccgcacgca acgcgtcggc
     3121 actcgccgca tccgtcagca ccaccgacgg ccgtgcgtcc gacagcatct gcgccaagcg
     3181 ttcttccggg taattcgggt ccagcggcac gtacgcgcct cccgctttca acaccgccaa
     3241 caccgcctcg aacaacgtcg gcgtgcgctg catgcagatc gccaccagcg catccggcgc
     3301 cacgccgcac atgcgcagat gccgtgcgag acgattcgcg gcgacgttca gcgcgtcata
     3361 actcacggtc gcgtcgcgcg tcgccagcgc atgcgcgtcg ggcgcgcgcg cggcatgcgt
     3421 ttcgaaaacg cgatgaagaa gcgtgggata cgggacggat tcgagactac acgggttcac
     3481 gacagggctc catttcgatc ccgacgcggc tcctgccgcg ttcgggcggg ggaagcgatg
     3541 cgccgcgggg gcggcgttcc atcgcctgag cgcgcctgcc gtcatcgacg ttccttggcg
     3601 cgcatggggt atcgcaagga caatcggaca cgatcgcccc gatgttcaaa ccacggcttc
     3661 ggtatcctcc gcggacacgt ccggggcgcc ttcggcatgc atggcgtcgt cctgcacgga
     3721 ctcgtccagc atcgcctcg
//
