LOCUS       c00133_3300027..        4056 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027793.a:Ga0209972_10020533.
ACCESSION   c00133_3300027..
VERSION     c00133_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 12:46:19
            Original ID  :: 3300027793.a:Ga0209972_10020533
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4056
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4056
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1742:4055](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1743..4055
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4056
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4056
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             2..421
                     /locus_tag="ctg133_1"
                     /transl_table=11
                     /translation="RLTPAAAPRLASRAERWGGVLLLLGLAVLLPLQLPAILGVLGQGT
                     LALILAVVALGLLIGHLLGGPEPAQRAVLASAVVHRHPAVALLLAMGSGTAADASVTGT
                     AADASVTGTVLLYMLVALLLPIPYERWRRRLVGAA"
     CDS             439..1185
                     /locus_tag="ctg133_2"
                     /transl_table=11
                     /translation="MPPAAVGLPTPVMRSSLRRQLLHLATDLSALAANPDDLGHGFDLF
                     SRSYVTPAADAARTALRQDPAIAPLIRERYWGRWPSQAELLALPAESLGHAFASWFAAA
                     GGQPLPDPVLQSGTSGDDTWLHLRVRHTHDLWHVVCGCPPTSAGEAAMSAVNVMQLRWP
                     GSAMLLGADLLHRCLEGPSAGQVDVGQAVAYGLELGRVCAPLLAQRWEEGWERPLAQWR
                     QQLGIAALVARSPFAANDGSAAAADR"
     CDS             1743..4055
                     /NRPS_PKS="Domain: AMP-binding (16-421). E-value: 3.8e-73.
                     Score: 238.1. Matches aSDomain:
                     nrpspksdomains_ctg133_3_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (536-604). E-value: 7e-18. Score:
                     56.4. Matches aSDomain: nrpspksdomains_ctg133_3_PCP.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 310;
                     E-value: 4.1e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg133_3"
                     /sec_met_domain="Condensation (E-value: 6.7e-16, bitscore:
                     45.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-77, bitscore:
                     248.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-14, bitscore:
                     42.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSPCSPIASRLDSAFAAIADRQPQATALSGSGGTQWTYRRLLVL
                     LEHTTGQLRRSGLQPADRVVLVAPSGPEGAAAILAVASCCTAAPVPAGLAAPALERRLR
                     RLAPRLMIVPDTTDPVIAAAAAACGLPVVALAAHPGSGQGLLAVEPAGPLPPAGRSFDT
                     AGAQGPGEPSALLLTTSGTTAEPRLVPLTHTNLLAAADSLRSVLALTSADRCLDPMPLA
                     HIHGLSLILASLLSGSQVHVPDSFSQDALLEAWQQLRPTWYSAAPAMHALIADWLQRRP
                     ELLTPPSLRFVRSASGPMPRPLLERLEGLLAVPLIEAYGMTEAAPQISSNRLPPHPRKA
                     GCVGRAAGPEIAILDAQGQPLPPGVSGEVAIRGANVMGGYLDDPEANRRSFHGPWLRTG
                     DLGHCDADGDLFLSGRLAERIERGGLAIAPEPIEALLLAHPLVREAAVFPVPHPLLGQM
                     VAAAVVLEGSPGSGPIDLPQELRQLILGQFDAHHVPQPLLVVPDLPVHPGGKRRRRDLA
                     AHFGLEPGGTAAPRALTDAERSLAALWAGVLGRAPALAQDNFFVLGGHSLAAASLVARL
                     GGRLGLELPPSWVFRLPTLAEQAADLGQRLTARLLSVPAAGPSTWPQPQSEGDQRLPPD
                     ATLAPLSPAQQGLWLLDRMGQGSAYSMAMGWELHGPLDPQLLSRSLQLLLTRQSSLRCV
                     VRLVDGQPMQQILPAAPLPLPLIVLPAGDAGGDADSSASASASASASADGDGDGQADGD
                     GEAEAARRQCERRAVALR"
     aSDomain        1791..3005
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg133_3_AMP-binding.1"
                     /evalue="3.80E-73"
                     /label="ctg133_3_AMP-binding.1"
                     /locus_tag="ctg133_3"
                     /protein_end="421"
                     /protein_start="16"
                     /score="238.1"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="AAIADRQPQATALSGSGGTQWTYRRLLVLLEHTTGQLRRSGLQPA
                     DRVVLVAPSGPEGAAAILAVASCCTAAPVPAGLAAPALERRLRRLAPRLMIVPDTTDPV
                     IAAAAAACGLPVVALAAHPGSGQGLLAVEPAGPLPPAGRSFDTAGAQGPGEPSALLLTT
                     SGTTAEPRLVPLTHTNLLAAADSLRSVLALTSADRCLDPMPLAHIHGLSLILASLLSGS
                     QVHVPDSFSQDALLEAWQQLRPTWYSAAPAMHALIADWLQRRPELLTPPSLRFVRSASG
                     PMPRPLLERLEGLLAVPLIEAYGMTEAAPQISSNRLPPHPRKAGCVGRAAGPEIAILDA
                     QGQPLPPGVSGEVAIRGANVMGGYLDDPEANRRSFHGPWLRTGDLGHCDADGDLFLSGR
                     LAERIER"
     aSModule        1791..3554
                     /complete
                     /domains="nrpspksdomains_ctg133_3_AMP-binding.1"
                     /domains="nrpspksdomains_ctg133_3_PCP.1"
                     /locus_tags="ctg133_3"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2262..2321
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg133_3_0001"
                     /evalue="1.40E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg133_3"
                     /protein_end="193"
                     /protein_start="173"
                     /score="11.7"
                     /tool="antismash"
                     /translation="ALLLTTSGTTAEPRLVPLTHT"
     CDS_motif       2826..2915
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg133_3_0002"
                     /evalue="7.70E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg133_3"
                     /protein_end="391"
                     /protein_start="361"
                     /score="27.9"
                     /tool="antismash"
                     /translation="PPGVSGEVAIRGANVMGGYLDDPEANRRSFH"
     aSDomain        3351..3554
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg133_3_PCP.1"
                     /evalue="7.00E-18"
                     /label="ctg133_3_PCP.1"
                     /locus_tag="ctg133_3"
                     /protein_end="604"
                     /protein_start="536"
                     /score="56.4"
                     /tool="antismash"
                     /translation="ERSLAALWAGVLGRAPALAQDNFFVLGGHSLAAASLVARLGGRLG
                     LELPPSWVFRLPTLAEQAADLGQR"
     CDS_motif       3714..3827
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg133_3_0003"
                     /evalue="3.80E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg133_3"
                     /protein_end="695"
                     /protein_start="657"
                     /score="32.2"
                     /tool="antismash"
                     /translation="SAYSMAMGWELHGPLDPQLLSRSLQLLLTRQSSLRCVVR"
ORIGIN
        1 ccggctcact ccggctgccg cgccgcggct ggcttcccgc gccgagcgtt ggggtggggt
       61 gctgctgctg ctcggcctgg cggtgctgct gccgctgcag ctccccgcga tcctgggagt
      121 ccttggacag ggaacactgg cactgatcct ggctgttgtg gccctgggcc tgctgatcgg
      181 gcacctgctg ggcggcccgg aacccgcgca gcgggcggtg ctggcttcgg cagtggttca
      241 tcggcatccg gccgtggcgc tgctgctcgc catgggctcc ggcacggcgg ctgacgccag
      301 cgtcaccggc acggcggctg acgccagcgt caccggcacg gtcctgcttt acatgctcgt
      361 tgccttgttg ctgcccatcc cctacgagcg ctggcgtcgc cggctggttg gcgcggccta
      421 ggcggctcct gggccaccat gcctccagct gccgtgggcc tgcctacccc tgtgatgcgt
      481 tcgtccctgc gccgccagct gctgcacctg gccaccgacc tctcggccct ggccgccaac
      541 ccggatgatc tggggcacgg cttcgatctg ttctcccgca gttacgtcac gccggcggcg
      601 gatgccgccc gcaccgccct gcgccaagac ccggccatcg cgccactgat ccgtgagcgc
      661 tattgggggc gctggcccag ccaggccgag ttgctggcgc tgccagcgga gagcctcggc
      721 catgccttcg ccagctggtt cgccgctgcc ggtggccagc cgctgccgga tccggtgctg
      781 cagtccggca cctctggcga cgacacctgg ctgcatctgc gcgtgcgtca cacccacgac
      841 ctctggcacg tggtgtgcgg ctgcccgccc acgtcggccg gggaagcggc gatgagcgcc
      901 gtgaacgtga tgcagctgcg ttggccaggc agcgccatgc tgctgggggc cgatctgctg
      961 caccgttgtc tggagggtcc atcggctggc caggtggatg tggggcaggc cgtggcctat
     1021 gggctggagc tgggtcgcgt ctgcgcgccc cttctggccc agcgctggga ggagggctgg
     1081 gagcggccgc tggcccagtg gcgccagcag ctggggatcg cggcgcttgt ggcgcgttca
     1141 cccttcgctg cgaacgacgg gtcagctgcg gcggctgacc gctgatcggg gcgcccgacg
     1201 gctaccagcg cgctaccggg gggattcagc ggcaggcgtc ggacccgcga cccctgcggc
     1261 aaccgaccgc cccgccgagc gagggccggg aagcctgctc actgctgacg ccccggacaa
     1321 cctggggcct tggcgcgacg gctccctgga cgggccatgg cagggccggt gctcgggctg
     1381 ccgctggtcc gtgtcgccgg cccgtgttga caggccatgg acgatgatga aaaaattatg
     1441 gcgaaatatc aagttctgaa tctccagaga aaagtcattc tctagagcaa actcatttta
     1501 tccgtctctg ttccttgcct gaaaaatgcg ctgattccga tcgcaaactt ctggcgactc
     1561 ctgctgggat tttccctcag atcaccgtct tggcgaggga gctcctgcgg ggattgatca
     1621 gcctgaagcc ctttgtagca gcagctctgt tcggctggtt caccgcagac ggtcggcgcc
     1681 tcagtgtttg cgctgctccc tctgttcgcc ccgccagccc gtctcggacc atcctgtagc
     1741 ccatgcagtc cccgtgttcc ccgatcgcat cccggctgga tagcgccttt gccgcgatag
     1801 ccgatcgtca gccgcaggcg acagccttga gcgggtccgg tggaacgcag tggacctaca
     1861 ggcggcttct ggtgctgctt gagcacacca ccggccaatt gcgccgctcc ggcctccagc
     1921 ctgccgacag agtcgttctc gtggctccct ccggcccgga aggggccgcc gccatcctgg
     1981 cggtcgccag ctgctgcacc gcggcgccgg tgccagccgg gcttgccgca cccgctctcg
     2041 agcggcgcct gcgacggctg gctccccgcc tgatgattgt tcccgacacc accgaccccg
     2101 tcatcgccgc ggccgccgcc gcctgcggtc tgccggtcgt cgcgctggcg gcccatcccg
     2161 ggtctgggca ggggctgctg gccgtggagc ctgccggccc gctgccgccc gcgggccgat
     2221 ccttcgacac ggcaggcgcc cagggccccg gcgagccgtc tgccctgctg ctcaccacct
     2281 cgggaaccac ggccgagccc cgccttgtgc ccctcaccca caccaacctg ctcgctgctg
     2341 ccgacagcct gcggtcggtt ctggcactca cgtccgcgga tcgttgtctc gatccgatgc
     2401 ccctggcgca tatccatggc ctgagcctga tcctggcctc cctgctcagc ggctcgcagg
     2461 tgcatgtgcc ggattccttc agccaggacg cgctccttga ggcctggcag cagctacgcc
     2521 ccacctggta ctcggcggca ccggcaatgc atgccctgat cgccgactgg ctgcagcggc
     2581 gacccgagct gctcacccct ccgtcgctgc gttttgtccg ctccgcttcg gggcccatgc
     2641 cccggcccct actggagcgc ctggagggcc tgctggccgt gcccctgatc gaggcctatg
     2701 gcatgaccga ggcggcgccc cagatcagca gcaaccgcct gcctccccat ccccgcaagg
     2761 ccggctgcgt cggtcgcgcc gcagggcctg agatcgcgat cctcgatgcc cagggtcaac
     2821 cgctgccgcc cggggtcagt ggcgaggtgg cgatccgcgg cgccaacgtc atgggcggtt
     2881 acctcgatga ccccgaggcc aatcgccgca gcttccacgg cccctggctg cgcaccggtg
     2941 atctcggcca ctgcgacgcc gacggggatc tgttcctgtc gggacggctg gcggagcgga
     3001 tcgagcgggg cgggctcgcc attgccccgg agccgatcga ggcgctgttg ctcgcccatc
     3061 ccctggtgcg cgaggccgcg gtgtttccgg tgccccatcc gctgctcggg cagatggtgg
     3121 ccgccgccgt cgtgctggag ggcagcccgg gatcaggacc gatcgacctg ccccaggagc
     3181 tgcgccagct gatcctcggg cagttcgatg cccaccatgt gccgcagccg ttgctggtag
     3241 tgcccgatct ccctgtgcac cccggtggca agcgccggcg tcgcgatctg gccgcgcact
     3301 tcggcctcga gcctgggggc acggccgccc cgcgggcgct cacggatgcg gagcgcagcc
     3361 tggctgccct ctgggccggc gttctcggca gggcgccggc actggcccag gacaactttt
     3421 ttgtgctcgg tggccattcg ctggcggccg ccagcctggt ggctcgcctc ggcggccgcc
     3481 ttggcctgga gctgccgccc tcctgggtgt tccgcctgcc gaccctggcg gagcaggcgg
     3541 ccgatctggg acagcgcctg acggcccggc tgctcagcgt gccagcggct ggtccctcga
     3601 cctggcccca gccgcagtcc gagggggacc agcgcctgcc gccggacgcg accctggcgc
     3661 ccctctcgcc ggcgcaacag ggcttgtggt tgctggatcg gatgggacag ggctccgcct
     3721 attccatggc catgggctgg gagctgcacg gtccgctgga cccccagctg ctcagccgca
     3781 gcctccagct gctgctcacc cgtcagagca gcctgcgctg cgttgtccgc ctggtcgatg
     3841 ggcagccgat gcagcagatc ctgcctgcgg cgcccctgcc gcttccgttg atcgtgcttc
     3901 ctgccggtga tgctggtggc gatgctgatt ccagtgccag tgccagtgcc agtgccagtg
     3961 ccagtgccga tggcgatggc gatggccagg ccgatggtga cggcgaggcc gaggccgccc
     4021 gtcggcagtg cgagcgccgg gccgtggcgc tgcgtc
//
