3300027869_22 - 8 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00007_3300027.. (original name was: 3300027869.a:Ga0209579_10001011)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	arylpolyene,ladderane,terpene	1	24,248

c00011_3300027.. (original name was: 3300027869.a:Ga0209579_10000111)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	T1PKS,NRPS	42,554	126,822

c00025_3300027.. (original name was: 3300027869.a:Ga0209579_10000205)

Region	Type	From	To	Most similar known cluster		Similarity
Region 25.1	terpene	56,749	78,728

c00027_3300027.. (original name was: 3300027869.a:Ga0209579_10000108)

Region	Type	From	To	Most similar known cluster		Similarity
Region 27.1	betalactone	28,190	55,533

c00036_3300027.. (original name was: 3300027869.a:Ga0209579_10003958)

Region	Type	From	To	Most similar known cluster		Similarity
Region 36.1	terpene	1	10,505

c00047_3300027.. (original name was: 3300027869.a:Ga0209579_10000058)

Region	Type	From	To	Most similar known cluster		Similarity
Region 47.1	terpene	109,474	130,343

c00059_3300027.. (original name was: 3300027869.a:Ga0209579_10000178)

Region	Type	From	To	Most similar known cluster		Similarity
Region 59.1	bacteriocin	1	7,737
Region 59.2	NRPS,T1PKS	13,278	67,366

Region	Type	From	To	Similarity
Region 7.1	arylpolyene,ladderane,terpene	1	24,248
Region 11.1	T1PKS,NRPS	42,554	126,822
Region 25.1	terpene	56,749	78,728
Region 27.1	betalactone	28,190	55,533
Region 36.1	terpene	1	10,505
Region 47.1	terpene	109,474	130,343
Region 59.1	bacteriocin	1	7,737
Region 59.2	NRPS,T1PKS	13,278	67,366

No secondary metabolite regions were found in these records:: c00001_3300027.. (original name was: 3300027869.a:Ga0209579_10013938); c00002_3300027.. (original name was: 3300027869.a:Ga0209579_10000099); c00003_3300027.. (original name was: 3300027869.a:Ga0209579_10001453); c00004_3300027.. (original name was: 3300027869.a:Ga0209579_10002949); c00005_3300027.. (original name was: 3300027869.a:Ga0209579_10000410); c00006_3300027.. (original name was: 3300027869.a:Ga0209579_10000098); c00008_3300027.. (original name was: 3300027869.a:Ga0209579_10002934); c00009_3300027.. (original name was: 3300027869.a:Ga0209579_10000631); c00010_3300027.. (original name was: 3300027869.a:Ga0209579_10000134); c00012_3300027.. (original name was: 3300027869.a:Ga0209579_10001568); c00013_3300027.. (original name was: 3300027869.a:Ga0209579_10000160); c00014_3300027.. (original name was: 3300027869.a:Ga0209579_10001006); c00015_3300027.. (original name was: 3300027869.a:Ga0209579_10006752); c00016_3300027.. (original name was: 3300027869.a:Ga0209579_10008207); c00017_3300027.. (original name was: 3300027869.a:Ga0209579_10027951); c00018_3300027.. (original name was: 3300027869.a:Ga0209579_10000368); c00019_3300027.. (original name was: 3300027869.a:Ga0209579_10000168); c00020_3300027.. (original name was: 3300027869.a:Ga0209579_10000556); c00021_3300027.. (original name was: 3300027869.a:Ga0209579_10000744); c00022_3300027.. (original name was: 3300027869.a:Ga0209579_10009591); c00023_3300027.. (original name was: 3300027869.a:Ga0209579_10002909); c00024_3300027.. (original name was: 3300027869.a:Ga0209579_10008292); c00026_3300027.. (original name was: 3300027869.a:Ga0209579_10000593); c00028_3300027.. (original name was: 3300027869.a:Ga0209579_10000397); c00029_3300027.. (original name was: 3300027869.a:Ga0209579_10008836); c00030_3300027.. (original name was: 3300027869.a:Ga0209579_10010291); c00031_3300027.. (original name was: 3300027869.a:Ga0209579_10028719); c00032_3300027.. (original name was: 3300027869.a:Ga0209579_10000190); c00033_3300027.. (original name was: 3300027869.a:Ga0209579_10023659); c00034_3300027.. (original name was: 3300027869.a:Ga0209579_10002982); c00035_3300027.. (original name was: 3300027869.a:Ga0209579_10007638); c00037_3300027.. (original name was: 3300027869.a:Ga0209579_10010932); c00038_3300027.. (original name was: 3300027869.a:Ga0209579_10000262); c00039_3300027.. (original name was: 3300027869.a:Ga0209579_10000126); c00040_3300027.. (original name was: 3300027869.a:Ga0209579_10000568); c00041_3300027.. (original name was: 3300027869.a:Ga0209579_10000062); c00042_3300027.. (original name was: 3300027869.a:Ga0209579_10001181); c00043_3300027.. (original name was: 3300027869.a:Ga0209579_10000335); c00044_3300027.. (original name was: 3300027869.a:Ga0209579_10000295); c00045_3300027.. (original name was: 3300027869.a:Ga0209579_10004150); c00046_3300027.. (original name was: 3300027869.a:Ga0209579_10000367); c00048_3300027.. (original name was: 3300027869.a:Ga0209579_10000148); c00049_3300027.. (original name was: 3300027869.a:Ga0209579_10000242); c00050_3300027.. (original name was: 3300027869.a:Ga0209579_10000248); c00051_3300027.. (original name was: 3300027869.a:Ga0209579_10000345); c00052_3300027.. (original name was: 3300027869.a:Ga0209579_10000061); c00053_3300027.. (original name was: 3300027869.a:Ga0209579_10002292); c00054_3300027.. (original name was: 3300027869.a:Ga0209579_10021031); c00055_3300027.. (original name was: 3300027869.a:Ga0209579_10000079); c00056_3300027.. (original name was: 3300027869.a:Ga0209579_10003280); c00057_3300027.. (original name was: 3300027869.a:Ga0209579_10018139); c00058_3300027.. (original name was: 3300027869.a:Ga0209579_10013580); c00060_3300027.. (original name was: 3300027869.a:Ga0209579_10001342)

Compact view

c00007_3300027.. - Region 1 - arylpolyene,ladderane,terpene

Download region GenBank file

Location: 1 - 24,248 nt. (total: 24,248 nt) Show pHMM detection rules used

Region on contig edge.

arylpolyene: (APE_KS1 or APE_KS2)
ladderane: ladderane
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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c00011_3300027.. - Region 1 - NRPS,T1PKS

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Location: 42,554 - 126,822 nt. (total: 84,269 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 42553 - 126822:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (redmal) + (ohmal) + (gly)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 42553 - 116737:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (redmal) + (ohmal) + (gly)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 82835 - 126822:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal) + (gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg11_59

PKS_AT (517..808): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 118.4
Methylmalonyl-CoA: 100.2
Isobutyryl-CoA: 75.6
Methoxymalonyl-CoA: 71.5
Ethylmalonyl-CoA: 64.6
Propionyl-CoA: 50.2
fatty_acid: 45.7
Acetyl-CoA: 40.0
2-Methylbutyryl-CoA: 38.4
CHC-CoA: 33.6
inactive: 29.9
Benzoyl-CoA: 29.1
trans-1,2-CPDA: 17.6
3-Methylbutyryl-CoA: 17.2

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 66.7%; CE-Malonyl-CoA: 62.5%

ctg11_64

PKS_AT (555..853): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 193.5
inactive: 132.7
Methoxymalonyl-CoA: 68.8
Methylmalonyl-CoA: 65.6
Propionyl-CoA: 38.7
Ethylmalonyl-CoA: 23.6
Isobutyryl-CoA: 20.3
fatty_acid: 20.2
2-Methylbutyryl-CoA: 17.9
Benzoyl-CoA: 17.6
CHC-CoA: 16.2
trans-1,2-CPDA: 12.8
Acetyl-CoA: 11.7
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 91.7%; 2-Rhyd-Malonyl-CoA: 62.5%

ctg11_66

Search NORINE for peptide: strict or relaxed

AMP-binding (505..897): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGmVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

c00025_3300027.. - Region 1 - terpene

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Location: 56,749 - 78,728 nt. (total: 21,980 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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c00027_3300027.. - Region 1 - betalactone

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Location: 28,190 - 55,533 nt. (total: 27,344 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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c00036_3300027.. - Region 1 - terpene

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Location: 1 - 10,505 nt. (total: 10,505 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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c00047_3300027.. - Region 1 - terpene

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Location: 109,474 - 130,343 nt. (total: 20,870 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

c00059_3300027.. - Region 1 - bacteriocin

Download region GenBank file

Location: 1 - 7,737 nt. (total: 7,737 nt) Show pHMM detection rules used

Region on contig edge.

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

c00059_3300027.. - Region 2 - NRPS,T1PKS

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Location: 13,278 - 67,366 nt. (total: 54,089 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 13277 - 67366:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro) + (mal - ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg59_25

Search NORINE for peptide: strict or relaxed

PKS_AT (531..827): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 175.8
inactive: 112.1
Methoxymalonyl-CoA: 68.0
Methylmalonyl-CoA: 52.4
Propionyl-CoA: 49.2
2-Methylbutyryl-CoA: 29.9
CHC-CoA: 24.6
Ethylmalonyl-CoA: 24.4
Benzoyl-CoA: 23.4
Acetyl-CoA: 22.0
Isobutyryl-CoA: 21.9
trans-1,2-CPDA: 14.0
3-Methylbutyryl-CoA: 11.8
fatty_acid: 9.9

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 91.7%; Propionyl-CoA: 54.2%

AMP-binding (2329..2722): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHISLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg59_26

Search NORINE for peptide: strict or relaxed

AMP-binding (26..392): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)