LOCUS       c00244_3300027..       10070 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027965.a:Ga0209062_1006943.
ACCESSION   c00244_3300027..
VERSION     c00244_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 03:16:34
            Original ID  :: 3300027965.a:Ga0209062_1006943
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10070
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10070
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6854:10070](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(6855..10070)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..10070
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10070
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(2..1732)
                     /locus_tag="ctg244_1"
                     /transl_table=11
                     /translation="MTQITDASTHTDNYVRAAAVADVQRAGSLLIRLAKHTIVLFYSDN
                     RVYAIDNRCPHMGFPLQGSTCKDGIVTCPWHYARFDLASGGTFDSWADDVRAFPVEIRD
                     GEVWINLAPQVDAHTQARQRLADGLEQGISLVIAKSVIALLDLGADPTEPFQIGLEFGT
                     RYNKEGWSTGLTIHTCMMNLLPFLDPEDRSSALYQGLSAVARDSAGAPPHFVVHPLPNS
                     SVDLDTLKGWFRQFIERRDSEAAERCLVSAIRMGAARQQIADMLFTAATDHRYIDGGHT
                     VDFINKALEALDTVDWHSAETVLASLVSGLANASRMEESSSWRYPVDLVAILESAFAEL
                     PATLEQGKALWGTWSGRDQLIPILLGENAQAIADGLLAALKEGCTPQQIAEVVTYTAAL
                     RVARFHTNNEHGDWDTAHHPFTFSNAVHQGLRRVSSPELLRGVFDAAMSVYLNRFLNVP
                     PARLPEPSSSVANPQKLLNQLPELLDRQQQVNEAGQLVANYLYSGGKAEQLMAMLGKLM
                     LRENRDFHVIQEIEAAFRQYSLLGQTPDGVHILVAVARYLAAHAPTMRSQAQTYHIAYR
                     L"
     CDS             1959..2273
                     /locus_tag="ctg244_2"
                     /transl_table=11
                     /translation="MGSEVKMSKYEWGSKLLTILNTVGTLFKSERRRKQPAIANRNSRI
                     QLIKIKKRGILWADLPLALVVVIAGSMVSKAGAIFPESVKVGRQPNGSVSTASMLTNSP
                     "
     CDS             2550..3188
                     /locus_tag="ctg244_3"
                     /transl_table=11
                     /translation="MTKVERESINFKLPKPLTAALRAKARQLNTTATDLVIQGLHHVLG
                     KAYDDGSDNSIKNILHDLITRIEALEENSTESAMETRLDYLETQLNYLESRLDRRQENG
                     VKDIEPLEEQLEALTTRIAQLEGAISILGQRQQAAPTRRQAFTYHPPQLELQPFTEENL
                     AKRLASSATTIRNHRATKSPKEFESWCRQRDPGGLAWRYQKDGLYHPVK"
     CDS             complement(3711..4298)
                     /locus_tag="ctg244_4"
                     /transl_table=11
                     /translation="MKLASLVKLKRTIRVIGFDDAPFIRGAGSSKVHIAGVVCAGTRFE
                     GMVWGQIQQDGLDATDAICKLLIGSKFLPQLHIVLLDGIGFGGFNLVNLQELASRLQLP
                     CVAVMRRQPDLVAVKEAMSRLPHFQYRLELLKLAGTIYESPPFVFQVSGEEPDVVALVL
                     QRLTDCGKVPEALRLSHLIAAAVIQGESGSSA"
     CDS             4558..4959
                     /locus_tag="ctg244_5"
                     /transl_table=11
                     /translation="MVALTENTQKRLSIQTVEIAPNTTAIRSLDWDRDRFDIEFGLQNG
                     TTYNSYLIKGDRIALVDTAHVKFRELYLETLKSLVNPKAIDYVIVSHTEPDHSGLVEEV
                     LQLAPRATVLASKVALQFLENLVQITFIV"
     CDS             4995..6584
                     /locus_tag="ctg244_6"
                     /transl_table=11
                     /translation="MDSTDSESWGYARVSTDEQAQDKDALIKQMQRLRDAGANKIFFDI
                     DKRTKHDRKGLLNLIKAVQELPINHNIRFLKFTRLDRVAASQVIFYKLISELQKKKIKP
                     IALDDPFDLDSVGGELTVDIRLDVAKHEVKMLGLRIRKERELRRKEKKSHFYAPFGYKI
                     EADKYIFNNDPCICLLANKEELSVVEVAQLILKIFYEVGSCTQTAKKLNEFFGISSKCS
                     EKYVRKSGNYLLDENDTLTQTTLNKKVDEKSNAGLRYPFSGLRWTTTGIRDWLTNPVLA
                     GGTPYDTVKENGYKKSFDEIKVFWNTHDNQALITFQQHQEIKEIIRSNRKNAWASHGDR
                     DPQKLNIFQGLIFCAKCNAKFVKVSTYQSRRDSKFKSYYQCTYYLKSGMCQQKTAITNF
                     DLEDQIIDFLVQEAERLAVLGEPANITVTESKELLELRSQLQALESIPGNNPAIETAKE
                     GLRLQISEWVNSGERSNQAMLISRERILAAFSNRNFWKGIQNPVDKKRLLRECIICAVV
                     DEGKVVEVRLRI"
     CDS             complement(6529..6687)
                     /locus_tag="ctg244_7"
                     /transl_table=11
                     /translation="MHNAHEGVESVAELIARLVCDHEARQVAEEQKKSTKFAALPLPLS
                     LHPQPRK"
     CDS             complement(6855..10070)
                     /NRPS_PKS="Domain: AMP-binding (45-447). E-value: 3.8e-102.
                     Score: 333.6. Matches aSDomain:
                     nrpspksdomains_ctg244_8_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (541-760). E-value: 7.8e-117. Score:
                     381.9. Matches aSDomain: nrpspksdomains_ctg244_8_nMT.1"
                     /NRPS_PKS="Domain: PCP (974-1042). E-value: 1.1e-27. Score:
                     87.8. Matches aSDomain: nrpspksdomains_ctg244_8_PCP.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     299.2; E-value: 7.4e-91)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg244_8"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-112, bitscore:
                     363.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.7e-17, bitscore:
                     50.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="EGIVANPEQRIATLPLVSASELHQLLVEWNNTQVKYPLDKCIHQL
                     FESMVEQSPDAIALVFEEQQLSYRELNIRSNQLAHYLIKLGVRNEVLVGLCVKPSFEMV
                     IGMLGILKAGGAYMLLDPSYPSERLNFMLEDAQVSVLLAHKQWMTSIGNPNLQVVYLNQ
                     DWEILSQEIESNPTSNIQPDNLAYVVYTSGSTGQPKGVQIEHRSLLNLVFWHQKAFKVS
                     PFERATQLAGIAFDACNWEIFPYLSAGASIYFIDDETRRSPEQLQDCLVSKAITMSFVP
                     TPLAEKLLLLDWPDNAALRVLLTGGDQLKQYPSASHPFQVVNNYGPTENTVVTTSGYVP
                     VSNCQDSFNPSFIAPTIGQAIANTQIYILDQHLQPVPIGIPGELYISGDGLARGYLNRL
                     DLTKEKFISHPFNDKSNSRLYKTGDLARYRLDGNIDFLGRLDQQVKIRGYRIELGEIEA
                     VLSQHPSVQQTIVITHEDAEQKLLVAYIALNAGYISDQDNMQLQNENEQVLQWQMVYNE
                     TYKQPGTDLDSTFNIVGWNSSFTNQPIPPEQMRAWVNNQVAQILALQPKQVLEIGCGTG
                     LMLFRIAPHCTKYCGTDFSPTSLNYIQQQLTKQEVPQVKLYQKMATDFEEIEEAAFDTV
                     ILNSVVQYFPSIDYLIRVLEGALRATAPGGFIFIGDVRSLPLLSAFHASVQLYQAESSL
                     TCEELRQRVQTQIFQETELVIDPAFFHALVQHFPQISDVQIQLMRGGDRNELTQFRYNV
                     ILHIGGESVNHTINNIEDDSLFDWHDDNLTVSRVHQFLIENQPKVLGITNVPNARVMAA
                     VKTAEWLSSAENLRTVAQMRKALQEFDNLGVDPEDWYTLAHQLAYKVDISWSASNCEGR
                     YDVVFVSQEAVDKKINFSRKMHLRSWQSYANNPLQMKAARKLVPQLQTYLAQRLPDYMI
                     PSTFVVLDALPLTANGKVDRRALPKVELGKLEWAGTYAAPRTPIEEMLVKIFAEVLGLK
                     QVGIHDNFFELGGHSLLATQFISRVRDSLHLELPLHTIFEAPTIAKLSQVVESFKASQI
                     QSQAPALVPLSRESRRMKLSSLE"
     aSDomain        complement(6945..7148)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg244_8_PCP.1"
                     /evalue="1.10E-27"
                     /label="ctg244_8_PCP.1"
                     /locus_tag="ctg244_8"
                     /protein_end="1042"
                     /protein_start="974"
                     /score="87.8"
                     /tool="antismash"
                     /translation="EEMLVKIFAEVLGLKQVGIHDNFFELGGHSLLATQFISRVRDSLH
                     LELPLHTIFEAPTIAKLSQVVESF"
     aSModule        6945..9935
                     /complete
                     /domains="nrpspksdomains_ctg244_8_AMP-binding.1"
                     /domains="nrpspksdomains_ctg244_8_nMT.1"
                     /domains="nrpspksdomains_ctg244_8_PCP.1"
                     /locus_tags="ctg244_8"
                     /monomer_pairings="leu -> NMe-leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(7791..8447)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg244_8_nMT.1"
                     /domain_subtype="nMT"
                     /evalue="7.80E-117"
                     /label="ctg244_8_nMT.1"
                     /locus_tag="ctg244_8"
                     /protein_end="760"
                     /protein_start="541"
                     /score="381.9"
                     /tool="antismash"
                     /translation="QPIPPEQMRAWVNNQVAQILALQPKQVLEIGCGTGLMLFRIAPHC
                     TKYCGTDFSPTSLNYIQQQLTKQEVPQVKLYQKMATDFEEIEEAAFDTVILNSVVQYFP
                     SIDYLIRVLEGALRATAPGGFIFIGDVRSLPLLSAFHASVQLYQAESSLTCEELRQRVQ
                     TQIFQETELVIDPAFFHALVQHFPQISDVQIQLMRGGDRNELTQFRYNVILHIGGES"
     CDS_motif       complement(8700..8765)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg244_8_0005"
                     /evalue="2.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg244_8"
                     /protein_end="457"
                     /protein_start="435"
                     /score="38.6"
                     /tool="antismash"
                     /translation="FLGRLDQQVKIRGYRIELGEIEA"
     aSDomain        complement(8730..9935)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg244_8_AMP-binding.1"
                     /evalue="3.80E-102"
                     /label="ctg244_8_AMP-binding.1"
                     /locus_tag="ctg244_8"
                     /protein_end="447"
                     /protein_start="45"
                     /score="333.6"
                     /specificity="consensus: leu"
                     /tool="antismash"
                     /translation="FESMVEQSPDAIALVFEEQQLSYRELNIRSNQLAHYLIKLGVRNE
                     VLVGLCVKPSFEMVIGMLGILKAGGAYMLLDPSYPSERLNFMLEDAQVSVLLAHKQWMT
                     SIGNPNLQVVYLNQDWEILSQEIESNPTSNIQPDNLAYVVYTSGSTGQPKGVQIEHRSL
                     LNLVFWHQKAFKVSPFERATQLAGIAFDACNWEIFPYLSAGASIYFIDDETRRSPEQLQ
                     DCLVSKAITMSFVPTPLAEKLLLLDWPDNAALRVLLTGGDQLKQYPSASHPFQVVNNYG
                     PTENTVVTTSGYVPVSNCQDSFNPSFIAPTIGQAIANTQIYILDQHLQPVPIGIPGELY
                     ISGDGLARGYLNRLDLTKEKFISHPFNDKSNSRLYKTGDLARYRLDGNIDFLGRLDQQV
                     KIRG"
     CDS_motif       complement(8853..8942)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg244_8_0004"
                     /evalue="4.80E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg244_8"
                     /protein_end="406"
                     /protein_start="376"
                     /score="50.8"
                     /tool="antismash"
                     /translation="PIGIPGELYISGDGLARGYLNRLDLTKEKFI"
     CDS_motif       complement(9069..9101)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg244_8_0003"
                     /evalue="3.00E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg244_8"
                     /protein_end="334"
                     /protein_start="323"
                     /score="10.2"
                     /tool="antismash"
                     /translation="NYGPTENTVVTT"
     CDS_motif       complement(9456..9515)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg244_8_0002"
                     /evalue="2.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg244_8"
                     /protein_end="205"
                     /protein_start="185"
                     /score="32.3"
                     /tool="antismash"
                     /translation="AYVVYTSGSTGQPKGVQIEHR"
     CDS_motif       complement(9708..9749)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg244_8_0001"
                     /evalue="6.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg244_8"
                     /protein_end="121"
                     /protein_start="107"
                     /score="13.2"
                     /tool="antismash"
                     /translation="LGILKAGGAYMLLDP"
ORIGIN
        1 acaaccgata agcaatgtga taagtttgtg cttgagaacg cattgtaggc gcgtgagcag
       61 ctagatagcg agccactgca actagtatgt gaacaccatc tggggtttga cccaataaag
      121 aatactgccg aaaagcagct tctatttctt gaatcacgtg gaagtctcgg ttttctcgta
      181 gcatcaattt acccagcata gccataagtt gttctgcctt accgccgctg taaagataat
      241 tagcgaccaa ctgacctgct tcgttgacct gttgttgacg atccaacaac tccggtagtt
      301 ggttcagcag tttttgtgga tttgcaactg aggatgaagg ttctggcagt cgtgctggtg
      361 gcacattcaa aaatcggttg agatacacac tcattgctgc atcgaaaaca cctcggagta
      421 actctggtga agacactcgc cgtaaccctt gatgcactgc attggagaag gtgaacgggt
      481 ggtgcgctgt gtcccaatcg ccgtgctcat tgttagtgtg aaatcgagcc acacggaggg
      541 ctgcagtata agtcactact tcagctatct gttgtggagt acaaccttcc ttcaaagcag
      601 ccaaaagtcc atcagctatt gcttgagcat tctcccctaa taagatagga atcaactgat
      661 ctcgacctga ccaagttccc cacagtgctt ttccctgctc tagggtagcg ggcaactcag
      721 caaaggcaga ttctagaatt gctactaaat ccactgggta ccgccaagaa ctagactctt
      781 ccatacggga agcattcgct agcccagaca caagacttgc cagaactgtt tccgcactgt
      841 gccaatctac agtatccagt gcttctaatg ccttattgat aaaatcaact gtatgaccac
      901 cgtcaatgta gcggtgatca gtggcagcgg taaacagcat atcagcaatt tgctgccttg
      961 ctgcacccat ccgaatggca gacactaaac agcgttctgc tgcttcacta tcccgccgct
     1021 caataaactg acgaaaccaa cctttgaggg tgtctaggtc aacacttgaa ttgggtaatg
     1081 ggtgaacaac aaagtgcggt ggcgcaccag cactatcacg ggcaactgct gacagtccct
     1141 gatacagcgc actagatctg tcttctggat ctaaaaaggg cagtaagttc atcatacagg
     1201 tgtggatagt taaccctgta ctccaccctt ccttgttgta acgcgttcca aattcgagtc
     1261 ctatttggaa aggttcagta gggtctgccc ccaaatctag caacgcaatc acggatttgg
     1321 ctatgaccaa ggaaatgcct tgttctaaac catcagcaag ccgctggcgt gcttgggtat
     1381 gagcatcaac ctgaggagct agatttatcc atacttctcc atccctaatt tctacaggaa
     1441 aagcccgcac atcatctgcc caagaatcga atgttccccc actggcaagg tcgaagcgtg
     1501 cataatgcca gggacaagtg acaattccat ctttacaagt gctgccttgt agaggaaagc
     1561 ccatgtgagg acaacggtta tctattgcat aaactctgtt atcggagtag aacaggacta
     1621 ttgtatgttt tgcgagccga atcaataaac tgcctgctcg ctgaacatcc gcaacagcag
     1681 cagcacgaac atagttgtct gtatgtgttg aggcatcagt tatttgagtc atatcagctt
     1741 tatcaaaaag tggagtatgt attaaatgag aaacactcct atttcttact ctgccgaact
     1801 tttaaacttt tgagttggta tcaaccctaa tttttgtaaa cttgcgtttg tgatgcgttg
     1861 atgtcttatt aaatctagaa ttgctgtaat ttaacgctcc cttaccatcc aattaatatg
     1921 tttgatttag actcattgct accctaacga attgaagcat gggaagtgaa gtaaagatgt
     1981 ctaaatatga atggggaagc aagctactaa caatactaaa tacagttggc actcttttca
     2041 agagtgaaag aaggcggaaa caaccagcaa ttgcaaatag aaatagcaga attcaattga
     2101 taaaaatcaa gaaaagaggc atactttggg ctgacctgcc attggctttg gttgtcgtga
     2161 ttgcaggcag tatggtgtcc aaagcaggtg cgatttttcc agagtctgtt aaggtgggac
     2221 gccaacctaa tggctctgtg tctacggcga gtatgctaac caactcaccc tagcagaagg
     2281 tgcgacaggc caatttggta actggattga ctggtacaaa gatgcattga ttttagaagg
     2341 caagcagaca ggcaatcttc atctcccggt atcttcaaag aacataacgc tgggagtatg
     2401 tcacaacaag agaaaaagaa cctcatagct tcgtgattta aattcgcggt ttgcccaatt
     2461 ggaatgcgcc ctatctttgt cctaaggaag aagatttgta ttcgaatttg gtttaaacta
     2521 tctacattat ggtacagaaa taagtgtaga tgacaaaagt tgagcgggaa tccattaact
     2581 tcaagctacc caaacccttg acagcagcgc ttagggcaaa ggctcgtcaa ctgaacacca
     2641 ccgccaccga tttagttatc cagggtctac accatgtttt gggtaaggca tatgacgacg
     2701 gttcagacaa cagcataaag aacattctgc acgacctcat tacccgtatc gaggcactcg
     2761 aagaaaatag tacagaaagt gctatggaaa ctcgcttaga ctacctggaa actcaattga
     2821 attatctgga aagccgtcta gatagacgac aagaaaatgg tgtaaaagat atcgaaccat
     2881 tggaggagca acttgaagca ctcacaacac gaatagcaca actcgaagga gctatttcaa
     2941 tacttggaca acggcaacaa gcagctccca caagacggca agctttcacc taccacccac
     3001 cacagctaga acttcaacca ttcaccgagg aaaatctagc gaaaagacta gcatcttctg
     3061 ccacaactat acgtaaccac cgggcaacca aaagtcctaa agaatttgag tcgtggtgtc
     3121 gccagcgtga tcccggtggt ttggcgtggc gctaccagaa agatggactt tatcatccgg
     3181 tgaaatagat tgactcttaa tactgtgttg caactttagg gaaataaata attgccaccc
     3241 tagtaaacag aaggtggcaa tgtaagttaa ttagcctgtt ttgtgcaaat cttacgttga
     3301 tattattttg acaaaaacac ccttcagtat gatttgttag taagttgtat tgtgctgatt
     3361 aacacaaata ttctttacgg aattgctgaa ataaggtttc agtggaatgc tcaaacacag
     3421 taaaatgcca cctccattta aggacgtgac agttaatgag actatgctct catttaagtt
     3481 gataattctg aggtaattct gaaaatctca atatgaagac tacaccaagt gaaaagtatg
     3541 tattgcccat caattattta actgttatta acttactcca gctcactgta gtcatttttg
     3601 gcaatttggc taatcattcc cggaccaaaa ggatagattg gtgcggtaaa tcgtcatgct
     3661 atcacggtta ccccagagtg atctctgggg ttttgctcta ggttatcgtt ctaggctgaa
     3721 cttccacttt ctccttgaat gactgctgct gctatcaaat gtgatagacg taaagcttct
     3781 ggcactttgc cgcagtcggt taaacgttgc agtacaagag ctaccacgtc aggttcttca
     3841 ccactcactt ggaagacaaa gggtggagat tcataaattg tacctgcaag tttcagtaac
     3901 tccagccgat actggaaatg tggcaggcga ctcatagctt ctttaacagc aactaaatca
     3961 ggctgacgac gcataacagc aacacagggt agctgaagcc gagaagctaa ctcttgtaga
     4021 ttaacgagat taaatccacc aaacccaatc ccatcaagta acacaatatg tagctgtggt
     4081 agaaacttgc tgccaattaa taacttacaa atggcatctg tcgcgtctaa cccatcttgc
     4141 tgtatctgtc cccacaccat accttcaaac cgcgttccag cacacactac tcccgctata
     4201 tgcaccttgc tactaccagc accccgaata aagggagcat catcaaaacc aataacgcga
     4261 atagtacgct taagtttaac tagagatgcc agtttcattc gtagtagttt cctttatgga
     4321 ttgcattttt ttagcaaaca tgtatgttca aaaataaatt ttattgatat aatttcttta
     4381 ttttaaaaaa gagtttaaat aacactttat aagtaagaaa atattctaga aaacagaatt
     4441 tttcgataca aagtgaattt caggaaaaat aaagttttta acaactttac aaaaataatt
     4501 gtgagcaaaa taaaaacaga aaagaagatt gattaaaatc tgcaagggag acgactaatg
     4561 gtagctctca cagagaatac ccaaaaacgc ctatctatac aaactgtaga aatagctcct
     4621 aatacaacgg cgattcgctc tcttgactgg gaccgcgatc gcttcgacat tgagtttgga
     4681 ctacaaaacg gtacaaccta taactcatat ctaattaaag gtgaccggat cgctttagtt
     4741 gatacagctc acgttaagtt ccgcgaactg tatttagaga cgctcaaaag cctcgtcaat
     4801 ccgaaggcaa tcgattatgt tattgtcagc cacacagagc cagaccacag tggcttggtt
     4861 gaagaggttc tccaattagc tcctagagcc actgttttag cgtcaaaagt tgcacttcaa
     4921 tttttagaaa atctagttca aatcacattt atagtgtaaa gtaaattcta taatcgttat
     4981 atggcttatg ttgtatggat tctaccgatt ctgagtcttg gggctatgcg agggtatcga
     5041 ccgacgagca agcacaggac aaagatgcac tcatcaagca aatgcagagg ttgagagatg
     5101 ctggtgctaa taaaatcttc tttgatatcg acaaacgtac caagcatgac cgtaaaggtc
     5161 tgcttaactt aatcaaagca gtccaagaac tgccgattaa ccacaatatt agatttttaa
     5221 aatttactcg attagataga gttgcagcat cgcaagtcat tttttacaaa cttataagcg
     5281 aacttcaaaa gaaaaaaatt aaacccattg cactcgatga cccattcgac ttggattcag
     5341 ttggagggga actgacggtt gatattcgct tagatgtagc caagcatgaa gttaaaatgc
     5401 ttggcttgcg aattcgtaag gaacgggaac tccggcgtaa agaaaagaag agtcattttt
     5461 atgcaccgtt tggctacaaa attgaagcag acaaatacat ctttaataac gacccatgca
     5521 tttgtctcct tgcaaataag gaagagttgt cagtagttga agttgcacaa ctgatattaa
     5581 aaatatttta tgaggtcggt agctgtacac agacagcgaa gaaattaaat gagttttttg
     5641 ggattagttc aaaatgttct gaaaaatatg ttaggaaatc aggtaactac ttacttgatg
     5701 aaaacgatac acttactcaa acaacactaa ataagaaagt agatgaaaag tctaatgctg
     5761 ggctacgtta cccattctca ggtctgagat ggactaccac tgggattcga gattggttaa
     5821 ctaatccggt gctggcaggt ggcactcctt atgacacagt taaggaaaat ggctacaaaa
     5881 agtcgtttga tgagatcaaa gttttttgga atacacacga taatcaagca ttaattacat
     5941 ttcaacagca ccaagaaatt aaagaaatta tccgtagtaa tcgaaagaat gcatgggcct
     6001 cacatggtga tcgcgatcca caaaaactta atatcttcca aggtttgata ttctgtgcaa
     6061 aatgcaatgc taagtttgtc aaagtttcga cctatcagtc tcgaagagat agcaagttta
     6121 aatcatatta ccaatgcacc tactatctaa aaagtggtat gtgccagcag aaaactgcta
     6181 ttaccaactt tgacctggaa gaccaaatta ttgactttct cgttcaggag gcagaacgcc
     6241 ttgctgtact gggagaacca gccaatataa cagtcacaga aagcaaggaa ttactggagt
     6301 tgcgatcgca acttcaagcg cttgaatcta ttccaggcaa taaccctgct attgagacgg
     6361 ctaaggaagg actgcgccta caaattagtg agtgggttaa tagtggggaa cggagcaacc
     6421 aggcgatgct tatcagtcga gaaagaattt tagctgcatt cagcaacagg aatttttgga
     6481 aagggataca aaaccctgtg gataaaaaac gcctgttacg tgaatgcatt atttgcgcgg
     6541 ttgtggatga agggaaagtg gtagaggtaa ggctgcgaat ttagtggact tcttttgttc
     6601 ttctgctact tgtcgtgctt catggtcgca tactaaacgt gcaatcaact ctgcaaccga
     6661 ttccacccct tcatgagcat tgtgcataga actcaaccaa gacttacaac ttaaaaataa
     6721 acatttgtca aaagacgtgc agtagcctaa ggcgcgatcg cacggtatga aaatgttctg
     6781 cgcaagccaa atgctgaagg ttgttgttta atttttaatt ttccattggc aaaaaagcta
     6841 tgtggcgatc gcacttattc cagagatgat aatttcattc gccgactctc gcgtgacagt
     6901 ggtactaaag ctggggcttg actttgaatt tggcttgctt tgaagctttc taccacttga
     6961 gataattttg ctattgtcgg tgcttcaaat atagtatgta acggtaactc tagatgtaaa
     7021 ctgtcacgca ctctagagat aaactgagtt gccagtaagg aatgacctcc taattcaaag
     7081 aaattgtcgt gaattccgac ttgcttaagt cccagaactt cagcaaagat tttgactagc
     7141 atttcttcaa taggagttcg aggtgcagca taagttcctg cccattctaa ctttcctaac
     7201 tcgaccttag gtaaagcgcg gcgatctact ttaccattag ctgtcagagg tagggcatct
     7261 agcacaacga aagtagatgg aatcatgtag tctggcagtc gttgggcaag ataagtctga
     7321 agctgaggca ctaacttacg ggctgctttc atttgtaggg gattattagc ataagattgc
     7381 caagaacgca agtgcatctt ccgtgaaaaa ttaattttct tatctacggc ttcttgactg
     7441 acaaaaacaa catcataccg cccttcacaa tttgaagctg accagctaat atcaactttg
     7501 taagccaatt gatgagccag cgtataccaa tcctctggat ctactcccaa attatcgaac
     7561 tcttgcaatg ctttacgcat ctgagcaact gttctcaaat tttctgcact cgatagccat
     7621 tctgcggttt tcactgctgc catgactcgc gcatttggta cattggtaat acctaaaacc
     7681 tttggttggt tctcaatcaa aaactgatgc actcgtgaga ctgttaaatt atcgtcgtgc
     7741 cagtcgaaca atgaatcatc ttcaatatta ttaatagtat gattaacact ttcaccaccg
     7801 atgtgaagaa tcacattgta acgaaactga gttaattcat tgcgatcgcc tccccgcatc
     7861 agttgaattt gtacatcgct aatctgggga aaatgctgca caagtgcatg gaaaaaagct
     7921 ggatcaatga ctaactctgt ttcttgaaaa atttgcgttt gtacacgttg ccgcaactcc
     7981 tcgcatgtca aggaagactc agcttgatac agttgtactg aggcatgaaa tgctgataaa
     8041 agtggcagac tacgcacatc tcctatgaag ataaaaccgc caggagcagt tgcccgtaaa
     8101 gcaccttcta agacgcgaat cagataatca atactgggaa aatattgcac aactgagttg
     8161 agaatcactg tatcaaaagc tgcttcttct atttcctcaa aatcagtagc catcttttga
     8221 tacagcttta cctgtggcac ttcttgcttg gtcaactgct gttgaatgta gttaagtgaa
     8281 gtaggtgaaa aatcagtccc acaatattta gtacagtgag gagcaattct gaacagcatc
     8341 agacctgttc cacaaccaat ctctagtact tgtttaggtt gtaaagccag aatttgtgcc
     8401 acttggttgt taacccacgc gcgcatttgt tctggtggaa tcggctgatt tgtgaaacta
     8461 ctattccaac ccacaatatt aaatgttgaa tctaagtcag tgcctggttg cttgtaagtc
     8521 tcgttgtata ccatctgcca ttgcaaaacc tgctcattct cattctgcaa ttgcatatta
     8581 tcctggtcac tgatgtatcc agcgttcagc gctatgtatg caactagaag cttttgctct
     8641 gcatcctcat gtgtgatcac tatagtttgc tgcacagatg gatgctgact caacacagct
     8701 tcaatttctc ccaactcaat tcggtaaccg cgaattttga cctgttgatc aagacgacct
     8761 aaaaaatcaa tgttaccatc tagtcgatag cgggctaagt ctccagtctt gtaaagcctt
     8821 gaatttgatt tgtcgttgaa aggatgagag ataaattttt cctttgttaa atccagacgg
     8881 tttaaataac ctcgtgctag tccatctcca ctgatgtaca actcacccgg aataccaatt
     8941 ggtacaggtt gtaaatgttg atcaagtatg tatatctgcg tgttggcgat cgcctgacca
     9001 attgtaggtg ctataaaaga ggggttgaag gaatcctgac aattgcttac aggaacgtaa
     9061 ccagatgtgg taactactgt attctcagta ggcccataat tattcactac ctggaaagga
     9121 tgagacgctg aagggtattg tttgagttgg tcaccacctg tgagtaacac tcgcaaagct
     9181 gcattatcag gccaatctaa taataataat ttctctgcta aaggtgtggg aacaaaactc
     9241 atggtgattg cttttgaaac taaacaatct tgtaactgtt caggcgatcg cctagtttca
     9301 tcatcaataa aataaatgct tgcaccagcg ctaagatagg gaaagatttc ccaattgcaa
     9361 gcatcaaagg caattccagc cagctgtgtt gctcgctcaa agggtgaaac tttaaatgct
     9421 ttttggtgcc aaaagaccag atttaacaaa cttctatgtt ctatttgaac tcctttaggc
     9481 tgaccagttg agccagaggt gtaaacgaca taagcaaggt tatctggttg aatattgctt
     9541 gtaggattac tttcaatttc ttgagaaaga atttcccaat cttgatttaa ataaacgact
     9601 tgtaaatttg ggttcccaat actcgtcatc cattgcttat gggctagtaa gactgaaact
     9661 tgagcatctt ctagcataaa gtttaaacgc tcagatggat aacttggatc taaaagcata
     9721 taagctccac cagctttgag gatgcccaac atcccgataa ccatctcaaa agagggtttg
     9781 acacaaagtc ctactaaaac ttcgtttctg actcctaact tgatgagata atgggcaagt
     9841 tgattgctgc ggatatttaa ttctcgatag ctgagctgtt gctcctcaaa taccagggca
     9901 atcgcatcag gactctgctc taccatgctt tcaaataatt gatggatgca cttgtctaga
     9961 ggatatttaa cctgagtatt gttccattca actaataact ggtgtaactc tgatgcactt
    10021 accagtggta aagttgcaat tcgttgttct ggattggcaa ctataccctc
//
