LOCUS       c00254_3300027..        4276 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027965.a:Ga0209062_1019298.
ACCESSION   c00254_3300027..
VERSION     c00254_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 03:16:34
            Original ID  :: 3300027965.a:Ga0209062_1019298
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4276
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4276
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:4274](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..4274
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4276
                     /SMILES="N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4276
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     aSDomain        3..596
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg254_1_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="9.30E-77"
                     /label="ctg254_1_Condensation_DCL.1"
                     /locus_tag="ctg254_1"
                     /protein_end="198"
                     /protein_start="0"
                     /score="249.8"
                     /tool="antismash"
                     /translation="DRKRGFNLSKAPLMHLTLIQQNERVYQFIWSYHHLLLDGWSLSLI
                     LKEVITFYESFQQGQDCYLQRPRPYRDYIAWLQQQDYSQAEAFWRRELKGITSPTCFRV
                     NQTSNSKVRQATEYGEEHLNLPVALTVALRSLTQQYQLTLNTLVQGAWVLLLSYYSGED
                     DVVFGVTSSGRPAALPGVESMVGLFINTLPVRVKVA"
     aSModule        3..3770
                     /complete
                     /domains="nrpspksdomains_ctg254_1_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg254_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg254_1_PCP.1"
                     /domains="nrpspksdomains_ctg254_1_Epimerization.1"
                     /locus_tags="ctg254_1"
                     /monomer_pairings="pro -> D-pro"
                     /tool="antismash"
                     /type="nrps"
     CDS             3..4274
                     /NRPS_PKS="Domain: Condensation_DCL (0-198). E-value:
                     9.3e-77. Score: 249.8. Matches aSDomain:
                     nrpspksdomains_ctg254_1_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (360-764). E-value:
                     1.8e-105. Score: 344.6. Matches aSDomain:
                     nrpspksdomains_ctg254_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (874-941). E-value: 4.8e-27. Score:
                     85.7. Matches aSDomain: nrpspksdomains_ctg254_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (953-1256). E-value:
                     3.7e-154. Score: 506.1. Matches aSDomain:
                     nrpspksdomains_ctg254_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1261-1416). E-value: 3.7e-47.
                     Score: 151.7. Matches aSDomain:
                     nrpspksdomains_ctg254_1_TIGR01720.1"
                     /NRPS_PKS="Domain: NRPS-COM_Cterm (1400-1421). E-value:
                     9.2e-08. Score: 23.6. Matches aSDomain:
                     nrpspksdomains_ctg254_1_NRPS-COM_Cterm.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     356.9; E-value: 2.3e-108)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg254_1"
                     /sec_met_domain="Condensation (E-value: 7.9e-75, bitscore:
                     237.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.4e-119, bitscore:
                     384.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.2e-16, bitscore:
                     45.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="DRKRGFNLSKAPLMHLTLIQQNERVYQFIWSYHHLLLDGWSLSLI
                     LKEVITFYESFQQGQDCYLQRPRPYRDYIAWLQQQDYSQAEAFWRRELKGITSPTCFRV
                     NQTSNSKVRQATEYGEEHLNLPVALTVALRSLTQQYQLTLNTLVQGAWVLLLSYYSGED
                     DVVFGVTSSGRPAALPGVESMVGLFINTLPVRVKVAFEESILPWLKNFQTQQLELRQYE
                     YTPLVKIQEWSDLPRGVPLFENIVVFENYPIEPSLQKGSSSLFVNYIRSIEQTNYPLSL
                     IVVPGSELYLKILYDRHHFDTASINRMLGHLKTLLEGIAHHPEQRLKDLPLLTPAEEHQ
                     LLTTWNNTQTNLQHRCIHELFETQVDQSPDAVAVVYQNESLSYQELNHRADQLAYHLRK
                     LGIRPEVRVGLCLNRSIEMLVGLLAILKAGGAYVPLDPVYPKERLAFILADAQVPVILT
                     QQALVEELPETGAQVVCLDINEEGIDWDSQHTSISHVTAENLAYVIYTSGSTGTPKGVA
                     LNHCALNNLISWQLQNSNAPGARTLQFTSLSFDVSFQEIFSTWCSGGTLILISEELRQE
                     PTALLSLLIDQAVERLFLPFIALQQLAEAANSQGLILHHLREIVTAGEALQITQQIACW
                     LETLKNCTLSNHYGPSESHVVTAFTLNGSKKSWPALPPIGHPITNAEIYLLNTYLNPVP
                     IGVPGEVYIGGISLARGYLNQPELTAETFIPNPYSKNPGARLYKTGDLASYQPDGNIQF
                     LGRIDDQVKIRGFRIELGEIETALSQHPKVQEAVVKAWEDKPGKKHLVAYIVPNQESIP
                     TLRELRSFLKEKLPEYMVPSAFMILDALPLTPSGKVNRRALPALDKTRPELESSFVAPQ
                     TPSEEILARIWAEVLGLERVGIYDNFFELGGDSILSIQIVARANREGLRFTTKQLFEYP
                     VLADLATLTSTTQSFPATQATVIGSIPLSPIQQWFFELDPLEPHHWNMAVLLEVPQDLS
                     LAMLAQIVQQLLIHHDALRLRFVRDASGWYQYNAEPDSSVPLLQVDLSTLPERQQKSTL
                     EAIASELQASLNLSHGPLLQVALFSLGADKPPRLLIAIHHLAVDGFSWRILLEDLQTAY
                     QQINRGEAVHLPPKTTSFKQWVEQLTEYTQSPALQQELTHWLTKPEIQIFRLPLDYPEG
                     TNTAGSTRTVPALLSVEETQALLLQVPKAYNTQINDVLLTALVLAFERWTGSRTLVVNL
                     EGHGREEILESVDLSRTVGWFTSVFPILLDLQGVYTLAEALKTVKEQLRRIPKRGIGYG
                     LLRYLSQDSEIKSKLRDLPQAEVTFNYLGQFDQTLAKSSGFKMARESSGISASPKGMRF
                     TRLYVGGMILHSRLHMDFNYSENLHQKSSIEAFAQIFLESLQSLIAHCQSPEARGRTPS
                     DFPKAKLSQKNLDKFIAKINQA"
     CDS_motif       96..161
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0001"
                     /evalue="5.50E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg254_1"
                     /protein_end="53"
                     /protein_start="31"
                     /score="31.7"
                     /tool="antismash"
                     /translation="YHHLLLDGWSLSLILKEVITFYE"
     CDS_motif       207..245
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0002"
                     /evalue="2.80E-04"
                     /label="C4_DCL_171-183"
                     /locus_tag="ctg254_1"
                     /protein_end="81"
                     /protein_start="68"
                     /score="13.2"
                     /tool="antismash"
                     /translation="PYRDYIAWLQQQDY"
     CDS_motif       492..587
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0003"
                     /evalue="2.50E-21"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg254_1"
                     /protein_end="195"
                     /protein_start="163"
                     /score="68.1"
                     /tool="antismash"
                     /translation="DVVFGVTSSGRPAALPGVESMVGLFINTLPVRV"
     CDS_motif       636..758
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0004"
                     /evalue="9.10E-23"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg254_1"
                     /protein_end="252"
                     /protein_start="211"
                     /score="72.8"
                     /tool="antismash"
                     /translation="QTQQLELRQYEYTPLVKIQEWSDLPRGVPLFENIVVFENYPI"
     aSDomain        1083..2294
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg254_1_AMP-binding.1"
                     /evalue="1.80E-105"
                     /label="ctg254_1_AMP-binding.1"
                     /locus_tag="ctg254_1"
                     /protein_end="764"
                     /protein_start="360"
                     /score="344.6"
                     /specificity="consensus: pro"
                     /tool="antismash"
                     /translation="FETQVDQSPDAVAVVYQNESLSYQELNHRADQLAYHLRKLGIRPE
                     VRVGLCLNRSIEMLVGLLAILKAGGAYVPLDPVYPKERLAFILADAQVPVILTQQALVE
                     ELPETGAQVVCLDINEEGIDWDSQHTSISHVTAENLAYVIYTSGSTGTPKGVALNHCAL
                     NNLISWQLQNSNAPGARTLQFTSLSFDVSFQEIFSTWCSGGTLILISEELRQEPTALLS
                     LLIDQAVERLFLPFIALQQLAEAANSQGLILHHLREIVTAGEALQITQQIACWLETLKN
                     CTLSNHYGPSESHVVTAFTLNGSKKSWPALPPIGHPITNAEIYLLNTYLNPVPIGVPGE
                     VYIGGISLARGYLNQPELTAETFIPNPYSKNPGARLYKTGDLASYQPDGNIQFLGRIDD
                     QVKIRG"
     CDS_motif       1269..1310
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0005"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg254_1"
                     /protein_end="436"
                     /protein_start="422"
                     /score="20.4"
                     /tool="antismash"
                     /translation="LAILKAGGAYVPLDP"
     CDS_motif       1503..1562
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0006"
                     /evalue="4.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg254_1"
                     /protein_end="520"
                     /protein_start="500"
                     /score="31.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVALNHC"
     CDS_motif       2082..2171
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0007"
                     /evalue="2.30E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg254_1"
                     /protein_end="723"
                     /protein_start="693"
                     /score="55.0"
                     /tool="antismash"
                     /translation="PIGVPGEVYIGGISLARGYLNQPELTAETFI"
     CDS_motif       2259..2324
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0008"
                     /evalue="5.10E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg254_1"
                     /protein_end="774"
                     /protein_start="752"
                     /score="40.8"
                     /tool="antismash"
                     /translation="FLGRIDDQVKIRGFRIELGEIET"
     aSDomain        2625..2825
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg254_1_PCP.1"
                     /evalue="4.80E-27"
                     /label="ctg254_1_PCP.1"
                     /locus_tag="ctg254_1"
                     /protein_end="941"
                     /protein_start="874"
                     /score="85.7"
                     /tool="antismash"
                     /translation="EEILARIWAEVLGLERVGIYDNFFELGGDSILSIQIVARANREGL
                     RFTTKQLFEYPVLADLATLTSTT"
     aSDomain        2862..3770
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg254_1_Epimerization.1"
                     /evalue="3.70E-154"
                     /label="ctg254_1_Epimerization.1"
                     /locus_tag="ctg254_1"
                     /protein_end="1256"
                     /protein_start="953"
                     /score="506.1"
                     /tool="antismash"
                     /translation="GSIPLSPIQQWFFELDPLEPHHWNMAVLLEVPQDLSLAMLAQIVQ
                     QLLIHHDALRLRFVRDASGWYQYNAEPDSSVPLLQVDLSTLPERQQKSTLEAIASELQA
                     SLNLSHGPLLQVALFSLGADKPPRLLIAIHHLAVDGFSWRILLEDLQTAYQQINRGEAV
                     HLPPKTTSFKQWVEQLTEYTQSPALQQELTHWLTKPEIQIFRLPLDYPEGTNTAGSTRT
                     VPALLSVEETQALLLQVPKAYNTQINDVLLTALVLAFERWTGSRTLVVNLEGHGREEIL
                     ESVDLSRTVGWFTSVFPILLDLQ"
     CDS_motif       2874..2903
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0009"
                     /evalue="4.00E-04"
                     /label="NRPS-E1"
                     /locus_tag="ctg254_1"
                     /protein_end="967"
                     /protein_start="957"
                     /score="13.3"
                     /tool="antismash"
                     /translation="LSPIQQWFFEL"
     CDS_motif       2928..3038
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0010"
                     /evalue="2.00E-06"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg254_1"
                     /protein_end="1012"
                     /protein_start="975"
                     /score="20.5"
                     /tool="antismash"
                     /translation="WNMAVLLEVPQDLSLAMLAQIVQQLLIHHDALRLRFVR"
     CDS_motif       3138..3176
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0011"
                     /evalue="2.10E+01"
                     /label="C3_dual_135-156"
                     /locus_tag="ctg254_1"
                     /protein_end="1058"
                     /protein_start="1045"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="STLEAIASELQASL"
     CDS_motif       3246..3311
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0012"
                     /evalue="4.70E-11"
                     /label="NRPS-E2"
                     /locus_tag="ctg254_1"
                     /protein_end="1103"
                     /protein_start="1081"
                     /score="34.8"
                     /tool="antismash"
                     /translation="LLIAIHHLAVDGFSWRILLEDLQ"
     CDS_motif       3714..3764
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0013"
                     /evalue="2.00E-08"
                     /label="NRPS-E5"
                     /locus_tag="ctg254_1"
                     /protein_end="1254"
                     /protein_start="1237"
                     /score="26.3"
                     /tool="antismash"
                     /translation="DLSRTVGWFTSVFPILLD"
     aSDomain        3786..4250
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg254_1_TIGR01720.1"
                     /evalue="3.70E-47"
                     /label="ctg254_1_TIGR01720.1"
                     /locus_tag="ctg254_1"
                     /protein_end="1416"
                     /protein_start="1261"
                     /score="151.7"
                     /tool="antismash"
                     /translation="LAEALKTVKEQLRRIPKRGIGYGLLRYLSQDSEIKSKLRDLPQAE
                     VTFNYLGQFDQTLAKSSGFKMARESSGISASPKGMRFTRLYVGGMILHSRLHMDFNYSE
                     NLHQKSSIEAFAQIFLESLQSLIAHCQSPEARGRTPSDFPKAKLSQKNLDKF"
     CDS_motif       3807..3869
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg254_1_0014"
                     /evalue="1.30E-11"
                     /label="NRPS-E6"
                     /locus_tag="ctg254_1"
                     /protein_end="1289"
                     /protein_start="1268"
                     /score="36.5"
                     /tool="antismash"
                     /translation="VKEQLRRIPKRGIGYGLLRYLS"
     aSDomain        4203..4265
                     /aSDomain="NRPS-COM_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg254_1_NRPS-COM_Cterm.1"
                     /evalue="9.20E-08"
                     /label="ctg254_1_NRPS-COM_Cterm.1"
                     /locus_tag="ctg254_1"
                     /protein_end="1421"
                     /protein_start="1400"
                     /score="23.6"
                     /tool="antismash"
                     /translation="PSDFPKAKLSQKNLDKFIAKIN"
ORIGIN
        1 tagaccgtaa gcgggggttc aacctctcca aggcgccgct gatgcacttg accctgattc
       61 aacaaaacga gagagtttac caatttatct ggagctatca ccacctactt ctagacggtt
      121 ggtctctgtc cttgatctta aaggaagtca ttacctttta tgaatcattc cagcaaggtc
      181 aggactgcta tctccaacgt ccccgcccct atcgggatta tattgcttgg ttacagcaac
      241 aagactactc tcaagctgaa gcattttggc gacgggaact taaagggatc acatcaccaa
      301 cttgttttag agtaaaccag acgtccaaca gcaaagtcag gcaagcaaca gaatatggtg
      361 aggaacacct caatctacca gttgctttaa cagtagcctt gcgatcgctg acccagcagt
      421 atcaactgac actgaacacc ttagtccagg gagcttgggt tctactactg agctactata
      481 gtggcgagga cgatgtggtc tttggcgtga cttcctccgg tcgtccagca gctttgccgg
      541 gagtggaatc tatggtaggg ctatttatca acactttacc agtacgggta aaggtggctt
      601 ttgaagagtc tattttacct tggctcaaga acttccaaac ccagcagcta gaactgcgtc
      661 agtacgagta cacaccactg gttaagatcc aagagtggag tgacttgccc cgaggtgtac
      721 ctttattcga gaatatcgtt gtttttgaga actatccaat agaaccctcc ttacaaaagg
      781 gaagcagcag cctgttcgtc aattatattc gttcaattga gcagacaaac tatcctctta
      841 gcctaattgt ggtaccaggc tcagaattat atttaaaaat tttatatgat cgccaccact
      901 ttgataccgc cagcattaac cgcatgctgg gtcatttgaa aaccttgctt gaaggtattg
      961 cccatcatcc agaacagcga ctaaaagact tgcccctctt gacgccagcc gaggaacacc
     1021 aactgctgac gacctggaat aacactcaaa ctaatcttca acacaggtgc atccacgaat
     1081 tatttgaaac tcaagtggat caatctcctg acgctgtggc agtagtttat cagaatgagt
     1141 ctttaagcta ccaagaactg aaccacagag cggatcagtt ggcgtatcac ttgcgcaaac
     1201 taggaataag accggaggtt cgtgtcggtc tgtgcctcaa tcgctctatt gagatgctag
     1261 tcgggctatt agctattctc aaagctggtg gtgcgtacgt gccgctagac ccagtctatc
     1321 ctaaagaacg tctggctttc attttggctg atgctcaagt gccagtcata ctcacccaac
     1381 aagcactagt ggaagaactg cccgaaactg gagcacaggt ggtgtgtcta gacataaacg
     1441 aggaggggat agattgggac agccagcaca cctccataag tcacgtcaca gctgagaacc
     1501 tagcctacgt gatctacact tccggctcaa caggtacacc caaaggcgtc gcactcaatc
     1561 actgtgccct gaataacttg atttcctggc aacttcaaaa ctcaaatgct cctggggcga
     1621 gaaccttgca atttacttct ttaagctttg atgtctcctt ccaagaaatt ttttcgactt
     1681 ggtgttctgg gggaacatta attttaatct cagaagaatt gcgacaagaa ccaaccgctt
     1741 tgttatcttt gcttatagat caggcagtcg aaagactatt tcttcccttt attgccctac
     1801 agcaactcgc cgaggctgct aattctcaag gattgattct ccaccatctt cgggagattg
     1861 tcacggcagg tgaagcgttg cagattactc agcagattgc ttgctggtta gaaacactaa
     1921 aaaattgtac attgtccaac cactatgggc cttccgagag ccatgttgta accgctttta
     1981 ctctcaatgg ttcaaagaag agttggccag cacttccacc cattggtcat cccatcacca
     2041 atgccgaaat ctatttgcta aacacctatt tgaatcctgt accaattggg gtgcctggtg
     2101 aagtgtacat tggtggaatc agtctagccc gaggctattt aaatcagcca gaattgactg
     2161 ccgaaacatt cattccaaat ccctacagca aaaatccagg tgcgcgcctt tataagaccg
     2221 gagacttagc cagctatcag cctgatggaa atatccagtt ccttgggcgc atcgacgacc
     2281 aagtcaagat tcgcggtttt cgtattgaac tcggagagat tgaaacagcc ctaagtcaac
     2341 atcccaaagt tcaggaagct gttgtcaagg cttgggaaga caaaccgggg aaaaagcacc
     2401 tcgtcgctta tattgtccca aaccaggaat caattcccac cctgcgggaa ctacgtagct
     2461 ttctcaaaga aaagcttcct gaatatatgg tgccgtcagc ttttatgatc ctagatgcac
     2521 taccactaac acccagtggg aaggtaaatc gtcgggcgct tcctgcgctt gataaaacta
     2581 gacctgaatt agaaagttcc tttgttgcgc ctcaaacgcc atctgaggag atactagcaa
     2641 gaatctgggc tgaagttctt ggacttgagc gggtcggcat ctacgataac ttttttgagt
     2701 tgggtgggga ttctattctc agtattcaga ttgttgctag agccaatcgg gaaggtttac
     2761 ggtttactac taagcagtta tttgagtacc cagtcctcgc cgatttagca acgctgacca
     2821 gcacaaccca aagtttcccc gccacacaag ctacagtcat tggttcgata cctcttagcc
     2881 caatccagca gtggtttttt gaactcgatc ctttagaacc ccaccactgg aacatggcag
     2941 ttctcctgga agtgcctcaa gacttaagcc ttgcaatgct agctcagatt gtgcagcaac
     3001 tgctcatcca ccacgatgca ctccgactcc gatttgttcg tgacgcctcg ggttggtatc
     3061 agtataatgc cgaacctgac tcatctgtgc ctttgttaca ggtagattta tcaacactgc
     3121 cagagagaca gcaaaaaagc actcttgagg cgatcgcatc agagttacaa gccagtttaa
     3181 acctgtcaca tggacccctg ctacaagttg cacttttctc cttaggtgca gacaagcccc
     3241 ctcgtctact tatagctatc catcatttag cagtcgatgg tttctcatgg cgcatccttc
     3301 ttgaagactt acagacagct taccagcaga tcaaccgtgg tgaagcagtt catctacccc
     3361 caaaaacaac ctcattcaaa cagtgggttg aacaactaac agagtacact caatccccag
     3421 cccttcagca agaacttacc cattggttga ctaagcctga gatccaaatt tttcgtctac
     3481 cattagacta ccctgaaggt acaaatacag caggttcaac ccgtactgtg cctgcactgc
     3541 tgagtgttga ggagacacaa gctctcctcc tgcaggttcc aaaggcatat aacacacaga
     3601 taaatgatgt gctgttgaca gcccttgtgc ttgctttcga gcgttggaca ggatcacgca
     3661 cactggttgt caaccttgag ggtcatggac gggaagaaat attagaatcg gtggatttgt
     3721 cgcgtacagt gggttggttc acttccgtct tcccgatttt gttggatctt caaggtgtgt
     3781 atacactggc tgaggcgtta aagacagtca aagagcagct ccgtcgtatc cccaaacgag
     3841 gtattggcta tggtctacta cgttaccttt ctcaagactc agagatcaag tcgaaacttc
     3901 gggatcttcc tcaagctgaa gtaacgttca attacctggg gcagtttgat cagaccctcg
     3961 caaaatcctc tgggtttaaa atggcaagag agtcttctgg aatatcagca agtccgaaag
     4021 gaatgagatt tacccgactt tatgtaggag ggatgatact acacagcagg ctacacatgg
     4081 attttaacta tagtgaaaac cttcaccaaa agtccagtat tgaggctttt gcccagattt
     4141 tcctagaatc attacagtca ctcattgctc attgccaatc tcctgaagca agaggtcgca
     4201 caccttctga ttttccaaaa gcaaagctga gtcagaaaaa cctcgataag ttcattgcca
     4261 aaattaacca agctga
//
