LOCUS       c00537_3300027..        6341 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027965.a:Ga0209062_1011987.
ACCESSION   c00537_3300027..
VERSION     c00537_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 03:16:34
            Original ID  :: 3300027965.a:Ga0209062_1011987
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6341
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1398
                     /locus_tag="ctg537_1"
                     /transl_table=11
                     /translation="PSSLSPQSPSKFMEQSQNLRTPIFAILQDIATLLLLAIAFPINCI
                     VVLAALLGNFLTRPFHKQVVANHRKNIMVTGGKMTKALQLARSFHAAGHRVVLVETHKY
                     WLTGHRFSNAVDRFYTVPAPQKDPEGYTQALVSIAKKENIDVYIPVCSPVASYYDSLAK
                     PALSAYCEVFHFDAEVTKMLDDKFTFSQKALSLGLSVPKTFLITDPEQVLNFDFTNEKR
                     KYILKSIAYDSVHRLDMTKLPMDSREKMAAHVRSLPISQDNPWLMQEFIPGKEYCTHST
                     VRNGFLRVYCCCESSAFQVNYENVDNPRIFQWVNHFVQQLKLTGQISFDFIEAEDGTVY
                     AIECNPRTHSAITMFYNHPKLADAYMSDAPDTDYPVQPLADSKPTYWLYHEIWRLTNIR
                     SYEQLKKWINSILRGKDAIFSVSDPLPFLAVHHWQIPLLLLNNLQRLKGWVRIDFNIGK
                     LVEVGGD"
     protocluster    1..6341
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3951:6339](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3952..6339
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..6341
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6341
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             1618..2610
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 121.2; E-value: 9.2e-37)"
                     /gene_kind="transport"
                     /locus_tag="ctg537_2"
                     /transl_table=11
                     /translation="MLKAKLKLPQEHLFATPTTVAFIALVASLMALSFSPILIRVSEGE
                     LGPNATIFNRFWISTVALMLWNGITTTRRQLSHSEPKKSEIYTSRVILLLLGVGFVMFA
                     TLILWAWSLNQTSVANSTLMHNLAPLFTVLTGWLVWGKRFDSRFLLGMVVAIAGACLLA
                     YHDFSSTTDQFQGDILALLSASFLGLYPLIVEELRTQLSPVVIMTWCSAIGTLLLLPIV
                     LLTEDKVFPCSLGGWLTVISLSLLCQILGLGLYAYCLNRLSSGFVSLCDLFVPVLSTQE
                     AWFIFSEKPNIATLISFAIIGLGVYVTSSSQSAINTAIDTAISTEVKSA"
     CDS             2676..3827
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046:Dioxygenase TauD/TfdA (Score: 245.5; E-value:
                     1e-74)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg537_3"
                     /transl_table=11
                     /translation="MNAMQNLPNSISSDMRLRFLQNNEKTFLMSETELPLVIEPVKEQS
                     FAVLKALLSESYDWFNQQLDTYGAILFRGFEIEDAKQFQKVLELLNVQLESFYHFGSAH
                     RVRITDKVFTSSEAPPDKIIAPHNELNMVPVRPGVLAFFCQVQPDLYGETPIINTEKLF
                     YSLSPSLQHKISTFPQRFVRYVPNHLLETVFEGLSQQEISQLLQEQGFDFQWEKDGSVS
                     FECSYIPLFSHPRTNRLCFCLSIVDCLVSREWYQKLGQRYSLGQKFYYNWLPAKLYKGF
                     QQGSTTAATVVDGSQKRTSTLNTYFVNGDNQYATMTEAEAKELGKAEWNNAAIFQWKQG
                     DILVIDNLQVAHSRLNTTLKRKILTAFGNMCSIHDMKPALLTS"
     CDS             3952..6339
                     /NRPS_PKS="Domain: AMP-binding (287-681). E-value:
                     6.6e-118. Score: 385.5. Matches aSDomain:
                     nrpspksdomains_ctg537_4_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     388.7; E-value: 5.5e-118)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg537_4"
                     /sec_met_domain="Condensation (E-value: 1.8e-18, bitscore:
                     54.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.2e-127, bitscore:
                     411.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKSLDLISSSSILELKNYWLNCLSGELPLLNLPTSLPRGSIKNY
                     NCSSYNFVINKRLTGLLKKLAESENVSLDTLLLAAFKVLLYRYTNEKDILVGLVLNQQI
                     SNFVNVVVSRNFITDNISFKKFLYQVNHTILEIRNYQDYPFALLVKELQPNSNSSHSPI
                     CQASFTFQTEHQQENISKLFEPAVTKQLINYGQLELEFDLSLEVIQLSELLQSSFKYNS
                     NLLDETTVTQISRHFENLLESIVSNSEQSVAQLPFLSEREREKILVEWNATQTDYDVTR
                     CLHQLIEAQVERTPDAIAVSFRGEHLTYRELNQRANQLAHYLQTLGVQPEVLVGICIER
                     SLEMLVGLLGILKAGAAYLPLDPGYPLERLELILSDSQVPVLLTDNQKLFANDEQRKVV
                     DLRRDQPNIATQSQDNPALGATPNNLAYVIYTSGSTGKPKGVAIPHNAVVNFLQSMQRE
                     PGITESDVLLAVTTVSFDIAALELYLPLITGAQVVLTTRELAIDGKLLKEFIDTVGATM
                     MQATPASWRMLLAAGWSGSPQLKILCGGEGLTSDLAQQLLKKGSAVWNLYGPTETTIWS
                     TVCRVDTTKLSHALVPIGRPIANTQIYILDSHLQPVPVGVLGELYIGGVGVARGYLNRP
                     ELSAERFISNPFSDSYRLYRTGDVARYLDDGTIEYISRIDHQVKIRGFRIELGEIENAL
                     STHPQVREAVVITRSAHTEDKQIVAYITTQQEQPTPESLRDFLKQKLPDYMVPTAFVRL
                     EALPLTPSGKVNRRALPKPTASNFCQHHEFVAPRTNSEWKLAK"
     CDS_motif       4348..4461
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg537_4_0001"
                     /evalue="4.60E-14"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg537_4"
                     /protein_end="170"
                     /protein_start="132"
                     /score="44.7"
                     /tool="antismash"
                     /translation="TILEIRNYQDYPFALLVKELQPNSNSSHSPICQASFTFQ"
     aSDomain        4813..5994
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg537_4_AMP-binding.1"
                     /evalue="6.60E-118"
                     /label="ctg537_4_AMP-binding.1"
                     /locus_tag="ctg537_4"
                     /protein_end="681"
                     /protein_start="287"
                     /score="385.5"
                     /specificity="consensus: gly"
                     /tool="antismash"
                     /translation="EAQVERTPDAIAVSFRGEHLTYRELNQRANQLAHYLQTLGVQPEV
                     LVGICIERSLEMLVGLLGILKAGAAYLPLDPGYPLERLELILSDSQVPVLLTDNQKLFA
                     NDEQRKVVDLRRDQPNIATQSQDNPALGATPNNLAYVIYTSGSTGKPKGVAIPHNAVVN
                     FLQSMQREPGITESDVLLAVTTVSFDIAALELYLPLITGAQVVLTTRELAIDGKLLKEF
                     IDTVGATMMQATPASWRMLLAAGWSGSPQLKILCGGEGLTSDLAQQLLKKGSAVWNLYG
                     PTETTIWSTVCRVDTTKLSHALVPIGRPIANTQIYILDSHLQPVPVGVLGELYIGGVGV
                     ARGYLNRPELSAERFISNPFSDSYRLYRTGDVARYLDDGTIEYISRIDHQVKIRG"
     aSModule        4813..5994
                     /domains="nrpspksdomains_ctg537_4_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg537_4"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4996..5037
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg537_4_0002"
                     /evalue="5.40E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg537_4"
                     /protein_end="362"
                     /protein_start="348"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LGILKAGAAYLPLDP"
     CDS_motif       5227..5286
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg537_4_0003"
                     /evalue="7.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg537_4"
                     /protein_end="445"
                     /protein_start="425"
                     /score="33.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVAIPHN"
     CDS_motif       5788..5877
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg537_4_0004"
                     /evalue="2.30E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg537_4"
                     /protein_end="642"
                     /protein_start="612"
                     /score="58.2"
                     /tool="antismash"
                     /translation="PVGVLGELYIGGVGVARGYLNRPELSAERFI"
     CDS_motif       5959..6024
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg537_4_0005"
                     /evalue="3.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg537_4"
                     /protein_end="691"
                     /protein_start="669"
                     /score="38.0"
                     /tool="antismash"
                     /translation="YISRIDHQVKIRGFRIELGEIEN"
ORIGIN
        1 ccatcctcct tgtcccccca gtccccttca aagtttatgg aacaatcaca aaacctgaga
       61 acccctattt ttgctatcct tcaagatatt gctacgctac tattattagc aatagcgttt
      121 ccgattaact gcatcgttgt cttagcagca ctgcttggga attttttgac tcgtccattc
      181 cacaagcaag tcgttgccaa ccatcgaaaa aatatcatgg tcactggcgg taagatgacg
      241 aaggcgctgc aactggcgcg ttcatttcat gcagctggac accgggttgt tttagtggaa
      301 actcataaat actggctcac tggtcataga ttttccaatg ctgttgatcg cttctacact
      361 gttcctgcac cacaaaaaga cccagaaggc tatactcaag ccttagtttc tatcgccaaa
      421 aaagaaaaca tcgacgttta tattcctgta tgtagtcctg tcgccagcta ttatgactcc
      481 ttagcaaagc cagcattatc agcctattgt gaggtgtttc actttgatgc tgaagtgaca
      541 aagatgttgg atgacaagtt tacctttagc caaaaggcac tgtctttggg tttatctgtc
      601 ccgaagactt tcctaattac tgaccctgaa caagttctca acttcgactt tactaacgag
      661 aagcgcaagt acattcttaa aagtattgct tatgattcag ttcatcgctt ggacatgacc
      721 aagctaccga tggactctcg cgaaaagatg gcagctcacg ttcggagttt gccaattagt
      781 caagacaacc cttggctgat gcaggaattt attcctggaa aagaatattg tacacacagc
      841 acagtgagaa atggtttctt aagggtgtat tgttgctgcg aatcatctgc ctttcaagtt
      901 aattatgaaa atgtagacaa cccaagaatt tttcaatggg tgaatcattt tgttcaacaa
      961 ctcaagctca ctggacaaat ttcttttgac ttcattgagg cggaagatgg aacagtttac
     1021 gcaattgagt gtaacccacg cacacattca gccattacca tgttctataa ccatccaaaa
     1081 ctagcggatg cgtatatgag tgatgctcca gatacggact accctgtgca gcctttggct
     1141 gatagtaagc ccacttattg gttgtatcac gagatttggc gactaacgaa tattcgctca
     1201 tatgagcaac taaaaaaatg gatcaacagt attttgagag gcaaggatgc aatttttagt
     1261 gtcagtgatc ctctgccatt tctagctgtt caccactggc aaattccctt gcttttactg
     1321 aacaatctgc aaagacttaa aggctgggtc aggatagatt ttaacattgg caaactggta
     1381 gaagtaggtg gtgactaagt aggctgatgg tatatactta ttctctatta ttgatgtatt
     1441 agtacatcat tctcgggtgt tgctttagtc aaaagctgat gcgcttaata ttgcaatttt
     1501 aatgcgctac agatcaacaa tgctgttgta aatagtacaa ttgtattctt aaccctaaac
     1561 aggcaacaaa gtagtcataa agacatatag acctagtaac agtattggaa aatattaatg
     1621 ctcaaggcta aactgaaact cccacaagaa cacttgtttg cgacaccaac tacagtcgca
     1681 tttattgcat tggtagctag cctaatggca ctatcttttt caccaattct catccgcgtg
     1741 agcgaaggtg aactaggccc aaatgcgaca atatttaacc gtttttggat ctctactgtc
     1801 gccttgatgc tgtggaatgg aatcacaaca actcgtcggc aactgtctca tagcgaacct
     1861 aaaaaatccg aaatctacac cagccgggta atcttactct tgctgggagt tgggtttgtt
     1921 atgtttgcaa ctcttattct ctgggcctgg tcactaaatc agaccagcgt cgccaactct
     1981 acgctcatgc acaatttagc ccccctgttc accgtcttaa cagggtggct ggtgtggggg
     2041 aagcggtttg atagtagatt tcttcttggt atggttgtag cgatcgccgg agcttgcctc
     2101 cttgcatacc atgatttttc atccaccact gaccaattcc aaggagatat attagcttta
     2161 ctctcagcca gttttcttgg tttataccca cttattgttg aagaactacg aactcaattg
     2221 agtccggtag tgatcatgac ttggtgttct gcgatcggca ctcttttgct tttgcctatt
     2281 gttctactaa ctgaagataa ggttttcccc tgttcattgg gtgggtggtt gaccgtaatt
     2341 tccttatcct tgttatgcca aatactaggg ctaggacttt atgcttattg cctcaaccga
     2401 ttatcttcag gatttgtctc tttgtgtgat ctgtttgttc ccgtgttgag cactcaggaa
     2461 gcttggttta tcttttcgga aaagccgaac atagctacct tgataagttt tgcgataatt
     2521 gggttaggcg tatatgtaac ttcatctagc caatctgcta tcaatacagc tatcgatact
     2581 gctatcagta cagaggttaa atcagcttag aaagaattgg tgaagactct taaagttatt
     2641 agtcaattgc taagaggctc aatattttta ctcttatgaa tgcgatgcaa aatcttccaa
     2701 attctatttc ttcagatatg agattacggt ttttgcagaa taatgagaaa acctttttga
     2761 tgtctgaaac agaattacct ctagtcatag agccagtcaa ggaacaatct tttgcagttc
     2821 tcaaagcact acttagcgaa agctatgact ggttcaatca acagctagat acatacggag
     2881 ctattttgtt tcggggattt gaaattgagg atgcaaagca atttcaaaaa gttctcgaat
     2941 tactgaatgt tcaactagag tccttttacc acttcggtag cgctcatcgt gtacgaataa
     3001 ccgataaagt cttcacctct tctgaagctc caccagataa gattattgct cctcacaatg
     3061 aactcaatat ggtccctgtg cgaccaggtg tactggcttt cttttgtcaa gttcagccag
     3121 acctttatgg tgagactccc attattaata cggaaaagct attttatagc ctatccccca
     3181 gcttacagca taaaattagt acatttcctc agcgatttgt gcgatatgtc cccaaccatc
     3241 tattggagac tgttttcgag ggtctttcgc aacaggaaat tagccaactt ctccaagagc
     3301 aaggatttga ttttcaatgg gaaaaagatg gctctgtttc ttttgagtgt tcttatattc
     3361 ccttattcag tcacccaaga acaaatagac tctgcttttg tcttagcatt gttgattgtt
     3421 tagtaagtag agaatggtat cagaagcttg ggcaacggta ttcattgggg caaaagttct
     3481 actacaactg gctaccagca aaattgtaca aaggctttca gcaaggatca acaacagcag
     3541 caactgtggt cgatggttct caaaaacgaa ctagtaccct caacacatat tttgtgaatg
     3601 gggacaatca atacgcgact atgacggaag cagaagcgaa agaattagga aaagctgaat
     3661 ggaacaatgc agcgatcttt cagtggaagc aaggtgatat tctcgtcata gataacctac
     3721 aggttgccca tagtagactc aacactacac ttaagcgaaa aatactcact gcattcggaa
     3781 atatgtgtag cattcacgat atgaaacctg ctttattaac aagttaagta gttgaacaaa
     3841 attaaattca ttcgttgaaa tagggaatag ggcatggggt tcccccaaga ctgcaatggc
     3901 tcctccatgt ccaaccttaa ctagtaatcg tttattctcc tcaatctact tatgcgcaag
     3961 tcattagatt tgatatcctc ctcttccatc ttggaactga aaaactattg gttaaactgc
     4021 ttatctggag aattgccttt acttaatttg cccactagct tacctcgagg ttctataaaa
     4081 aattacaatt gctcttccta taactttgta attaataaga ggttaactgg attactgaaa
     4141 aagcttgcag aaagtgaaaa tgtcagcctt gacactctcc ttttggcagc atttaaagtt
     4201 ctactgtatc gctatacaaa cgaaaaagat attcttgttg gtttggtatt aaatcagcaa
     4261 attagcaatt ttgttaatgt agtagtatcc aggaatttca ttacagacaa tatttcattt
     4321 aaaaagtttt tgtatcaagt taatcatact atcttagaaa tcagaaatta tcaagattat
     4381 ccatttgctt tattggtgaa agaattacag cctaattcta actcaagcca ttcacctatt
     4441 tgtcaagctt catttacttt tcaaactgaa catcaacagg aaaatatatc aaagttattt
     4501 gagccagcag tcactaaaca gctaatcaac tatggccaac tcgaacttga atttgatttg
     4561 agtttggaag tcatccaact ttctgaatta ttgcagagta gctttaaata taatagtaat
     4621 ctgttagatg aaacgacagt tactcagata agcagacatt tcgagaattt actggaaagt
     4681 attgtatcta attcagaaca atcagtagct cagttaccat tcctaagtga gagggaacgg
     4741 gagaaaatac tggttgagtg gaatgctact cagactgatt atgatgttac gagatgtctt
     4801 caccaattaa tcgaagcaca ggtagagcga acaccagatg cgatcgcagt ctcttttaga
     4861 ggagaacatc tgacctatcg tgaactgaat cagcgtgcaa atcaactagc gcactactta
     4921 caaacactgg gagttcaacc agaggtattg gtgggtattt gcattgagcg ttctttagaa
     4981 atgctggtgg gacttttggg tatcctgaaa gctggtgcag cttacctacc tttagatcca
     5041 ggatatccac tagaacgctt ggaattgatc ttatctgatt ctcaggtacc agtgttgttg
     5101 actgataatc aaaagctatt tgctaatgat gaacaaagga aagtcgtcga tttacgtaga
     5161 gatcagccaa acatagctac ccaaagccaa gacaatcctg cactaggtgc tactcccaac
     5221 aatctggctt atgttattta cacctccggc tcaactggta agccaaaagg cgtcgcaatt
     5281 cctcacaacg ctgtagtcaa tttcttacaa tccatgcagc gtgaacctgg aattacagag
     5341 tcagatgtac ttttagcagt gactacagta tcatttgata ttgctgctct agagctatat
     5401 ctgcctctga ttacgggtgc tcaggtggtg ttaactaccc gagaactagc gatagatggc
     5461 aagttactca aagaattcat tgataccgtc ggcgctacaa tgatgcaagc tactccagcc
     5521 agttggcgga tgttgctggc ggctggatgg agtggttctc ctcaattaaa aattctctgt
     5581 ggtggcgaag gcttaaccag cgacttagca cagcaattat taaaaaaagg ttccgctgta
     5641 tggaatcttt acggaccgac tgaaacgact atttggtcaa ctgtctgtag agtagacact
     5701 acgaagttat ctcatgcttt agtccccatt ggtcgtccca ttgccaatac acaaatttac
     5761 atattagatt ctcatctcca accagttcca gtgggagttc ttggcgaatt gtatataggt
     5821 ggtgttggag tggcacgcgg ctacctcaac cgtccggagc ttagtgctga aagatttatt
     5881 agtaatccct tctcagacag ttaccgtctt tacagaacag gagatgtggc tcgttacttg
     5941 gatgatggca ctattgaata cattagccgg attgatcacc aagtaaaaat tcgagggttc
     6001 cggattgaac ttggggaaat agaaaacgct ctatctactc acccacaagt gcgagaagcg
     6061 gttgtgatca ctcgttctgc tcatacagag gacaaacaaa tagtagcgta tatcacgacc
     6121 caacaagaac aaccaacacc tgaatctctg cgtgactttc tcaaacagaa gttaccagat
     6181 tacatggtgc caacagcctt tgtgagatta gaagcattac ctttaactcc cagtggaaaa
     6241 gtcaatcgcc gcgcattgcc aaagccaaca gcttctaact tttgccaaca ccatgaattc
     6301 gtcgcaccgc gcaccaattc cgaatggaag ctagcaaaaa t
//
