LOCUS       c00566_3300027..       10931 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027965.a:Ga0209062_1006300.
ACCESSION   c00566_3300027..
VERSION     c00566_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 03:16:34
            Original ID  :: 3300027965.a:Ga0209062_1006300
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10931
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10931
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4402:7525](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4403..7525)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..10931
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10931
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(248..730)
                     /locus_tag="ctg566_1"
                     /transl_table=11
                     /translation="MSANKKLGQKWIFNWFFGFNEIPTSEDSLTYMKSVLCCAKADGVL
                     SAEEREWVLGFCASWGVEDWVIEELKTYEANEPIEEVIARSPQVSMAQRDILLCAIWAC
                     AADRQYHEEEKVKVRQMASILGVSEKVVEQLEQLYQEESALQQKRVKLLYPEKSPY"
     CDS             complement(1225..1722)
                     /locus_tag="ctg566_2"
                     /transl_table=11
                     /translation="MTTNIKESETNLGISWLFKEQFGFSQIPANVSYEAYFKSLLICAN
                     GDGTLADAERDWVIGYASAYNRDSAVIEKLKVYKADEDLETVFSGDPLISETRRSLILD
                     AIQACAADGEYSEKERAIVLKGAKILNISEDELKKIEEIYFETVKLREKRLAVIFPKGL
                     PY"
     CDS             complement(2034..3209)
                     /locus_tag="ctg566_3"
                     /transl_table=11
                     /translation="MKQSLIETLLDISEQEKERLLAAIQIDAITESPYQENESAESREY
                     RQFFQSLFQKILHFEENDQQILFDVARSVRQKYFRNKGILRGVIEVANACERSCNYCPM
                     RIENEELGERYNFASETILETAIEIKESSIPIVFIQAGEIRATTRTVSKAISQIRQLFE
                     NNVIILLNLGDKPKEDYITLKEAGANQYIIKFETSNWNLHKQARGYPLSERLARIDDLL
                     SLGYEVGSGTIVGLKAVDANGQTEIEQTPKMLANDLLLAMKKKIHMCSASPFIPGKGTP
                     LAHTSPGNANMTLNWMALARIMMPKVLIPSVSALNVLLGQDGQLKGLQAGANTITVNFT
                     PPNYQDQYAIYSKQKRYKVKYEYALDIMRKAGIEPTLLPNTPSRSFLLSQN"
     CDS             complement(3211..3300)
                     /locus_tag="ctg566_4"
                     /transl_table=11
                     /translation="MKGNMEHKRNTAILVGLKSEKYTIENKDK"
     CDS             complement(3297..4364)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 314.9; E-value:
                     1.1e-95)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg566_5"
                     /transl_table=11
                     /translation="MKNLAKEFMFQTQLPHSLMKDETQTTQTLKQMIAGAWITQGIYVV
                     AQLGIADLLKDDSKSYAELAITTGVHARSLYRLLRALASVGIFAEASSGYFELTPLAEC
                     LQSDHPNSLRGYAIKSGQPWEWEPWGHLLESIKTGKPVFKNIFGMERFDYLATDPSASK
                     IYTQAISSISDKQDAAIATGYDFSSIHNLVEVAGGSGTLIASILKANLTMQGVLFDLPH
                     VVAEARPLIEGLGLQDRCQLVGGDFFKSVPTGGDAYLLRYIVHDWDDERAIAILKNCYQ
                     AMQPNGRLLLVEMVIPPGNEPFFGKLLDLQMLINYGGSERTEAEYQILLETAGFSQTKI
                     YPLAPPVSVIEAIRQ"
     CDS             complement(4403..7525)
                     /NRPS_PKS="Domain: AMP-binding (23-423). E-value: 1.2e-108.
                     Score: 355.1. Matches aSDomain:
                     nrpspksdomains_ctg566_6_AMP-binding.1"
                     /NRPS_PKS="Domain: ACP (552-624). E-value: 2.2e-12. Score:
                     38.9. Matches aSDomain: nrpspksdomains_ctg566_6_ACP.1"
                     /NRPS_PKS="Domain: TD (668-908). E-value: 5.3e-85. Score:
                     276.2. Matches aSDomain: nrpspksdomains_ctg566_6_TD.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     403.6; E-value: 1.7e-122)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg566_6"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-123, bitscore:
                     401.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.1e-11, bitscore:
                     31.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.3e-73, bitscore:
                     234.7, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 9.3e-10,
                     bitscore: 26.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFSSPYPDILIPDQPLTEFVLQRATELADKPALIEGISNRVITY
                     KKLADSVRRVASGLAVRSFSKGDVLAIYSPNLPEYAIAFHAVAINGGIITTVNPSYTVE
                     ELAYQLNDASAKYLITIPELLEQALEAVSQSKVEEIFVFGEAAEATPFSALLEGEGEIP
                     KVQINPKEDLVALLYSSGTTGMPKGVMHSHYTFVANFHQFKNCEPVSEADAVIGVLPFF
                     HCYGLVMLNYNLAFGATIVTMPCFDLETFLSLIEKHKITRIHVVPPILLALAKQSIVDK
                     YNLSSLRVLNSGAAPLSYQLIKECEQRFPNCIVKQAYGTTETTMTTHTLDERDKIKPGS
                     VGQCLPHVECQIVDVDTQQPLSFHQPGELWIRGPQIMKGYLNNPEATAKAIDQEGWYHT
                     GDIVYVDEDGYFYIVDRIKELIKCNGYSIAPAELEAVLLSHPAIADACVVKSPHPSSGE
                     VPKAFIVLKARATQEEIMQFVAERVAPHKMLRRLEFVDNIPKSASGKILRRILVQQELT
                     KVTEASSHEQPLQLQREFLQQLDDASLHQRQELLIAYIREQFVTVLGITTSQHLDIEKP
                     LHELRLDSLMNIDLKNRIDTELGVDMPIEMLLGDSNISQLVNVLLQQLAAKNTTFSKKA
                     SAELATDLNSEVILDPTIKPEYPFEPLVTEPAAILLTGATGFLGAFLLQELLLKTQANV
                     YCLVRAADVELGKVRIENNLSSYGIWNEAFASRVIPIVGDLSQPLLGLSLQEFHELSRL
                     IDVIYHNAAWINYVYPYAALKPTNVLGTQEILRLASQIKIKPVHYISTVAVFESPAYWG
                     KVVTESDQLAYSEGMRLAYSQSKWVAEKLVMIARDRGIPVAIYRPPFIAGHSQTGAWYK
                     DDVICRTIKGCIQMGSMTDITDRLDLAPVDYLSQSIVYLSKQMDSLGKAFHLNNPQPLS
                     WKELTDFINSLGYQIKHISYEDWQIQLNKSVRSKENPLYHLLPFYQRQSPQKKLGVSEQ
                     YQQSIDPKISCLVTQDALAGSFIVCPPVNFQLLNTYFSYFLRTDWLDLAQN"
     aSDomain        complement(4802..5521)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg566_6_TD.1"
                     /evalue="5.30E-85"
                     /label="ctg566_6_TD.1"
                     /locus_tag="ctg566_6"
                     /protein_end="908"
                     /protein_start="668"
                     /score="276.2"
                     /tool="antismash"
                     /translation="ILLTGATGFLGAFLLQELLLKTQANVYCLVRAADVELGKVRIENN
                     LSSYGIWNEAFASRVIPIVGDLSQPLLGLSLQEFHELSRLIDVIYHNAAWINYVYPYAA
                     LKPTNVLGTQEILRLASQIKIKPVHYISTVAVFESPAYWGKVVTESDQLAYSEGMRLAY
                     SQSKWVAEKLVMIARDRGIPVAIYRPPFIAGHSQTGAWYKDDVICRTIKGCIQMGSMTD
                     ITDRLDLAPVDYLSQSIVY"
     aSModule        4802..7456
                     /complete
                     /domains="nrpspksdomains_ctg566_6_AMP-binding.1"
                     /domains="nrpspksdomains_ctg566_6_ACP.1"
                     /domains="nrpspksdomains_ctg566_6_TD.1"
                     /final_module
                     /locus_tags="ctg566_6"
                     /monomer_pairings="leu -> leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(5654..5869)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg566_6_ACP.1"
                     /evalue="2.20E-12"
                     /label="ctg566_6_ACP.1"
                     /locus_tag="ctg566_6"
                     /protein_end="624"
                     /protein_start="552"
                     /score="38.9"
                     /tool="antismash"
                     /translation="AYIREQFVTVLGITTSQHLDIEKPLHELRLDSLMNIDLKNRIDTE
                     LGVDMPIEMLLGDSNISQLVNVLLQQLA"
     aSDomain        complement(6257..7456)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg566_6_AMP-binding.1"
                     /evalue="1.20E-108"
                     /label="ctg566_6_AMP-binding.1"
                     /locus_tag="ctg566_6"
                     /protein_end="423"
                     /protein_start="23"
                     /score="355.1"
                     /specificity="consensus: leu"
                     /tool="antismash"
                     /translation="RATELADKPALIEGISNRVITYKKLADSVRRVASGLAVRSFSKGD
                     VLAIYSPNLPEYAIAFHAVAINGGIITTVNPSYTVEELAYQLNDASAKYLITIPELLEQ
                     ALEAVSQSKVEEIFVFGEAAEATPFSALLEGEGEIPKVQINPKEDLVALLYSSGTTGMP
                     KGVMHSHYTFVANFHQFKNCEPVSEADAVIGVLPFFHCYGLVMLNYNLAFGATIVTMPC
                     FDLETFLSLIEKHKITRIHVVPPILLALAKQSIVDKYNLSSLRVLNSGAAPLSYQLIKE
                     CEQRFPNCIVKQAYGTTETTMTTHTLDERDKIKPGSVGQCLPHVECQIVDVDTQQPLSF
                     HQPGELWIRGPQIMKGYLNNPEATAKAIDQEGWYHTGDIVYVDEDGYFYIVDRIKELIK
                     CN"
     CDS_motif       complement(6356..6430)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg566_6_0002"
                     /evalue="1.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg566_6"
                     /protein_end="390"
                     /protein_start="365"
                     /score="33.8"
                     /tool="antismash"
                     /translation="PGELWIRGPQIMKGYLNNPEATAKAI"
     CDS_motif       complement(6947..7000)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg566_6_0001"
                     /evalue="1.30E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg566_6"
                     /protein_end="193"
                     /protein_start="175"
                     /score="20.9"
                     /tool="antismash"
                     /translation="LLYSSGTTGMPKGVMHSHY"
     CDS             complement(8098..10929)
                     /locus_tag="ctg566_7"
                     /transl_table=11
                     /translation="LFCASFLAVKLSLINSGFLGAIIGVVIWSTYFLVLVWMGSSALGS
                     VTGALVSTATSGVQGLMGTATAAISANAAKAQMVSTVEDITAAVRRELTSGLDPNSIRN
                     ALQSSLASLPLPKLDLQEVRNQFARLLSDANLQSLGDSDVLKNINRQTFVDLLSSRTDF
                     SKEDINRIADQLEDAWKEVVNRQNPTDRVIDFLWSATSRELNSEHLGERLQELVTVGGN
                     GSKSNDANGGGGIQPLIQYGLSAAVPAVLNRVDFSNVDVDKVTSVLPKLKEKVQDLDID
                     KITSQLKHLGDQTREQIAKQLPASSDNTIKTDVENYIRNSFPWHFNRITIKDEFKDIIY
                     DPNADPSTVKRQLEELNAEYFNNLLTQRDDINEARVKEIVEQLESVRLEVLETVQQSAT
                     RKQFQDFRTRIEEYLRSTPKEELNLESIEREFARLLEDPEAGVEDLSDRFGELNRDVFV
                     QLLQQRGDFNEEEANNIIGQLELSRDHILNRARELQEQAKAKADELRQRVEDYLRNTGK
                     EELNPEGIKRDFRVLLEDPQAGISLLRTRLSQFDRDTLAKLLSQRQDLDEEQVNQILDQ
                     LEAVRDNILQAPQKVADKAKEQYEQTTRTIAEYLRNTNLEELNPEGIQQDLTKLLQNPQ
                     EGINALRDRLSQIDRETLVKLLAQRGDLSEEQANRIIDAVQEAISRIVQAPGRLATRAT
                     QKVLDFEANLEDYLRHTRKEELNPEGIKRDLRLLLSSPRTGVASLGERFSKFDRSTLVA
                     LLSEREDISEEEANRIVDQIESVGNSIIEQSRQVQQRVQSVIDQIFDSIRNYLNSLNRP
                     ELNYESLQQDFAKLFDDPQAGFEALRDRLSQFDRDTLVAIVSSRQDISEEQANKIINQI
                     EAARDSVINRSQYIQQETQKRLTAIRDQAKKQAEETKKVVARAAWWVFNIAWVSLAASA
                     IAGALGASSGVMP"
ORIGIN
        1 tgtctcgtat gtcaagtctt atcagggttt tgttattttt tgacacattt tcttcatcct
       61 tatttacgta tttaactatt tttttggcat agtaagtact gaagaaccat aaatttacac
      121 atttgagttg agatgctctc aaccagaatt aatataattc tatgattttt aattctggtg
      181 gtaatggaaa acccaagctt tgatgaaaat gccttagact tgagccaatc agagtactat
      241 aagagggtta gtaggggctt ttttcaggat ataaaagttt gacacgcttc tgctgtagtg
      301 ctgactcttc ttggtatagc tgctctaatt gctcaactac tttttcagac acacctaaaa
      361 tagaagccat ttgacgaact tttacttttt cctcttcatg atattgtctg tcagctgcac
      421 aagcccaaat tgcacacaga agtatatctc tctgtgccat agatacttga ggagagcgag
      481 caataacttc ctctataggt tcatttgctt catatgtttt cagttcctca atcacccagt
      541 cttctacacc ccaagatgca caaaatccta gaacccattc tctttcttct gctgagagta
      601 ctccatctgc tttagcacaa cataaaacag atttcatata agtgaggcta tcttcacttg
      661 ttgggatttc gttaaaacca aagaaccaat taaatatcca tttttggcca agttttttat
      721 ttgcagacat aaatttttaa atcactacag aaatagtatc tcattgtcct aacaaggata
      781 tcaagtactc ataaaaaaca tcttactttt cctacttttc ctatttttct tacttttctt
      841 acttttatag taaatgcgag caacaataag tttgcatgtt atgaaattaa ttgtatatag
      901 cagttctaga tgagttgtaa aaatcaaaag tctcagaaac ccggtttctc gtttttcacg
      961 aatgatttag gatttctata gatgcaatcg catttaattg tagtcaataa aaagctacct
     1021 tctcaggatt gaggaaggca gctcatttgg cataatttcc aataactgtt tgttgtgcct
     1081 ctattgtagc atttttgtaa tactgatatt gagagtcatc atttttctca gtgactacac
     1141 ttagtctttg ctcacaccca tctagcaatt taaattcaaa aagcttgtat ttcttgctag
     1201 tgccgagatt gtctaagtgc taatttagta aggtaaccct ttgggaaata tgactgctag
     1261 acgtttctca cggagtttga ctgtctcaaa atagatttct tcaatctttt ttaattcatc
     1321 ctcggaaata ttgagtatct tggctccttt aagtactata gcccgttctt tctcgctata
     1381 ttcgccatca gcagcacaag cttggatcgc atcaagaatt agagaacgtc gtgtttcact
     1441 gattagaggg tctccactaa atactgtctc tagatcttca tctgccttgt aaactttgag
     1501 tttttcaata actgcagagt cgcgattgta tgcagaggcg tatccaatca cccaatctct
     1561 ttctgcatct gctaatgtac catcaccatt agcacaaata agcagcgatt taaagtaagc
     1621 ttcataagat acatttgcag gaatttgtga aaaaccgaac tgttctttaa acaaccaaga
     1681 gatgcctaaa ttagtctcac tttctttgat atttgtcgtc attactattt ccttaaatga
     1741 ctcagttctt taacttataa acttgattat tgcataaatg aataatattt aaaaccaaaa
     1801 aatagtaatt attttttttt aaattcataa ttatctccat ttcaaactaa tagctttcag
     1861 atatacaaag ctatctttaa cctatgtttt gtgatgttga atcttctatt ttctgtctat
     1921 gctctataac gccagttgct accctaccct gcgggaacgc tttcagcgaa cgggaagccg
     1981 cccttcaggc gtctacaacg gaggatatct cagcatttaa gcagtgggaa gctctaattt
     2041 tgagaaagca aaaaactccg gctaggcgta ttaggtaata aagttggctc gatacctgct
     2101 tttctcatga tatctaaagc atactcgtat ttgactttat accgtttttg tttgctgtaa
     2161 atagcatact ggtcttgata gttgggaggc gtaaaattca cggtgattgt atttgctcct
     2221 gcttggagtc cttttaactg accatcttgt cctaataaaa cattaagagc acttacacta
     2281 ggtatcaaaa cttttggcat cataattcta gctaaagcca tccaatttaa agtcatatta
     2341 gcgttgcctg gactcgtatg agctagtgga gtacctttgc caggtataaa aggagatgca
     2401 ctacacatat ggattttctt cttcatggca agaaggagat catttgctag catctttgga
     2461 gtttgttcaa tttcagtttg tccattagca tctacagctt ttaaaccaac aattgttcca
     2521 cttcccacct cataccctaa acttaataaa tcatcaattc tagctaagcg ctcagataaa
     2581 ggatatcctc tagcttgttt gtgtaaattc caattgctcg tttcaaattt aataatgtat
     2641 tgatttgcac cagcttcttt gagtgttatg taatcttctt taggtttatc accaagattc
     2701 agcaagataa tgacattatt ctcaaaaagt tgtctaattt gggatatggc tttagataca
     2761 gttctcgtcg ttgctctaat ttcaccagct tgaataaata caatgggaat actcgattct
     2821 ttgatttcta ttgcagtttc taatattgtt tcacttgcga aattataacg ctctcctaat
     2881 tcttcatttt caattctcat tgggcaataa ttacaacttc tttcacaagc attagcaacc
     2941 tcgatgacac cccttaaaat tcctttattt ctaaaatact tctgacgtac agatcttgct
     3001 acatcaaata gtatttgctg atcattttct tcaaaatgaa gtattttttg aaagagggat
     3061 tggaaaaatt gtctatattc tcgggattct gctgactcat tttcttgata tggactctca
     3121 gtaatggcat caatttggat ggctgctaaa agtcgctctt tttcctgctc tgaaatgtct
     3181 agtagagttt caatcaaact ttgcttcatg ttatttatct ttattctcta tggtgtattt
     3241 ttcagatttc aacccaacta aaatcgctgt attccttttg tgttccatgt tccctttcat
     3301 tgacgaatgg cctcaattac gctgactgga ggtgctaatg gataaatttt tgtttgagaa
     3361 aaacctgctg tttctagtaa gatttgatac tcagcttcag tccgttcaga tccaccataa
     3421 tttatgagca tctgcaagtc gaggagtttg ccgaagaatg gttcgttacc tggaggtata
     3481 accatttcga ctagtagcaa tctcccgtta ggctgcattg cttgatagca atttttcaag
     3541 atggcaatcg ccctttcatc atcccaatcg tgaacaatat accgcagcaa gtaagcatct
     3601 ccacctgtgg gtactgactt aaagaagtcc ccaccaacta gttgacagcg atcttgcaat
     3661 ccaagacctt caatcaaagg ccttgcttct gcaactacat ggggtaagtc aaataaaacc
     3721 ccctgcattg tcaaattagc tttgagaatc gaggcaatca aagtaccact tccacctgcc
     3781 acctcaacta agttgtggat agatgagaag tcgtaaccag ttgcgatcgc tgcatcttgc
     3841 ttatcagaaa tactacttat ggcttgagtg tatattttag aagcagaagg gtcagtagct
     3901 aggtaatcaa atctctccat cccgaagata tttttgaata caggtttgcc cgttttaata
     3961 ctttcaagta aatgtcccca cggttcccat tcccagggtt gaccagactt gatagcataa
     4021 ccacgtaggg agttagggtg atcactttgc agacattcag caagaggtgt caattcaaaa
     4081 tagcctgaac tagcttcagc aaatatacca acactagcaa gggcgcgtag tagccgatag
     4141 agcgatcgcg catgtacacc agttgttatt gctaactcag cataactttt agagtcatct
     4201 ttgagtaaat ctgcaatacc aagttgagca actacataaa taccttgtgt aatccaagca
     4261 ccagcaatca tttgcttgag tgtttgtgta gtctgtgtct catccttcat tagagaatgt
     4321 ggtaattgag tttgaaacat aaattccttt gctaaatttt tcatttttaa ctttaaattt
     4381 ttaactactt ccttccattt tgctaatttt gagctaaatc gagccaatca gtgcgaagaa
     4441 aatatgagaa ataagtattg agcaattgaa aattcacagg aggacaaact ataaaactac
     4501 ctgctaaagc atcctgtgtt accaaacaac taattttcgg gtctattgat tgttgatatt
     4561 gctctgaaac acctagtttt ttttgaggtg actgtctttg ataaaaaggc aagagatgat
     4621 acaaaggatt ttctttagaa cgtacagact tatttagctg tatttgccaa tcttcataag
     4681 aaatatgctt aatttgatag ccaagagaat tgataaaatc agttagttcc ttccaagaaa
     4741 gaggttgagg attatttaag tgaaaagcct ttccaagaga atccatttgc ttggataaat
     4801 acacaatact ttggctgagg taatcaacag gagctaaatc taatcggtca gtgatgtctg
     4861 tcatgctccc catttgtata cagcctttaa tagtgcggca aattacatca tctttatacc
     4921 aagcacctgt ttgactatga ccagcaataa atggtggtct ataaatcgca accggaatac
     4981 cgcgatcgcg tgctatcatc accaactttt ctgccaccca tttactctga gagtaagcca
     5041 gtctcattcc ttcactataa gcgagttgat cagattcagt gactaccttt ccccaataag
     5101 caggtgattc aaaaacagca acagtagaaa tataatgcac tggcttaatt tttatttgac
     5161 tcgccaatct caagatttcc tgagttccta aaacattggt aggctttaat gccgcataag
     5221 gataaacata gttaatccaa gcagcattgt gataaatcac atcaatcaga cgacttaact
     5281 cgtgaaactc ttgcaatgac aaacctaaca gtggttgaga taaatccccc acaataggga
     5341 taactctaga agcaaaagcc tcattccaaa ttccataaga acttaaatta ttttcaatcc
     5401 ttactttacc taactcaaca tcagcagcac gtactaagca ataaacattc gcctgggttt
     5461 ttagcagcag ttcttgaagc aaaaaagctc ctaaaaagcc tgttgcccct gtcaacaaaa
     5521 tagctgctgg ctcagttaca agtggctcaa atggatattc aggtttgata gtagggtcta
     5581 atataacttc tgaatttaaa tctgttgcta actcagccga tgcttttttt gagaaagttg
     5641 tgtttttcgc tgctagttgc tggagcaata catttaccaa ttgactgata ttggagtcgc
     5701 caagcaacat ttctatgggc atgtctaccc ctagttcagt atcaatacga ttctttaaat
     5761 cgatattcat gagagaatca agcctgagtt catgcaaagg cttctctata tccaaatgtt
     5821 gagaagtagt gatgcctaaa actgtgacaa attgctctcg aatgtaagca atcaatagtt
     5881 cttgacgttg atgcaaagaa gcatcatcca attgttgtag aaactcccgt tgtagctgca
     5941 atggctgctc atgagaggat gcttcggtga cttttgtcag ttcttgttgt actaatatgc
     6001 ggcgcaaaat tttgccagaa gcagatttgg gaatgttgtc tacaaattca agtctgcgca
     6061 acattttatg tggtgcaact cgctcagcaa caaactgcat aatttcctct tgtgtagccc
     6121 ttgcttttag tacgataaaa gctttgggaa cttcaccact actaggatga ggactcttga
     6181 ctacacaagc atcagcgatc gccggatggc tcaacaatac tgcttcaagt tcggctggtg
     6241 ctatggagta gccattgcac ttaatcaact ctttgatgcg atcaactata taaaagtaac
     6301 cgtcttcatc aacataaaca atatcgccag tatgatacca accctcttga tcaattgctt
     6361 tggcagttgc ttctggatta ttcaaatagc ctttcatgat ttgcggtcca cgtatccaca
     6421 actctcctgg ttgatgaaaa cttaatggtt gttgggtatc gacatctacg atttgacatt
     6481 ccacatgagg aagacattga cccactgaac caggcttaat tttgtcacgt tcatctaggg
     6541 tgtgggtagt cattgtggtt tctgtcgttc catatgcctg cttgacgata caattaggaa
     6601 aacgttgttc gcactctttg atcaattgat aacttagagg tgctgctcca gaatttagca
     6661 cccgtaagct agaaagatta tatttatcta ctattgactg ttttgccagt gccaacaaaa
     6721 ttggtggaac gacatggata cgggtgattt tgtgcttttc aatcaggctt agaaaagtct
     6781 ctaaatcgaa gcacggcatg gtcacaatag ttgctccaaa agcaaggttg taattcagca
     6841 tgaccaagcc gtagcaatga aaaaaaggca aaactccgat aactgcatca gcctcgctga
     6901 ctggttcgca gtttttgaat tggtgaaagt tggcaacaaa tgtatagtgg ctgtgcatca
     6961 cacctttagg cataccagta gtgccactag agtagagtaa agctactaga tcttcttttg
     7021 gattgatctg tacttttggt atttctcctt caccttctaa aagcgcagaa aatggagtag
     7081 cttcagctgc ctcaccaaag acaaatatct cttctacctt tgactgacta accgcttcta
     7141 atgcttgctc caaaagttca ggtatagtga tgagatattt agcactagcg tcattgagtt
     7201 gatatgccag ttcttctact gtataggatg ggttgactgt ggtgatgatg ccaccattaa
     7261 ttgctacggc atgaaaagcg atcgcatatt cggggagatt cggactgtaa atagctaaaa
     7321 catcaccctt tgagaaacta cgcaccgcta ggccgctagc gactcgacgg acagaatctg
     7381 ctagtttttt atatgttatt acacggttac ttattccttc aattagggct ggcttgtctg
     7441 ctaactctgt tgctcgttgc aatacaaatt ctgtcagtgg ctgatcaggg attaaaatat
     7501 cagggtatgg actgctaaag atcataatat ctctttattc tattaaatat ttaatagtta
     7561 tccattgagt gcaaaaaaag catcacaaaa catcctaatt ggcggggcga tcatgctaat
     7621 agttgcattt ttattattaa tattcttagt aaattactta tagcagaatg atagcagtta
     7681 cttcgtgttt tacaacaaaa aagtattaaa taacccactt ttcttacttt tcctactttt
     7741 tgagcccaag actaattaat acgtgtaata tctttttaaa acatcaatag cagagtcttg
     7801 ctgaaaacaa cagacttgca tgctaacgac tctcacaaga aaccgattgc acagatgcgc
     7861 tcacgataat acatggagaa aaccccacct caactttcaa tcccaaattt cttgcaaaca
     7921 gagaaaaaat ggcgttgctg aatcaaagta tgagtgtgca attcacggat atgtagagac
     7981 gtagcaatgc tacgtctcta caaggatttt gattttgact acaaaaatat tacaagcaca
     8041 attcatgtgt aaattcagca acaccagaga gttactggca ttcacagctg gaagggctca
     8101 aggcatgacg cctgaggatg ctcctaaagc tcctgctatt gctgaggcag caagggaaac
     8161 ccaagctatg ttaaagaccc accaagcagc acgtgcaaca actttcttag tttcttcagc
     8221 ttgcttttta gcttggtctc taatcgctgt tagacgtttt tgcgtttcct gttgaatata
     8281 ttgagatctg ttaatgacac tatctcgtgc cgcttctatt tggttaatga ttttattagc
     8341 ttgctcttcg gaaatatcct gacgagagct aacaatggca actagagtgt cacgatcaaa
     8401 ttggctgagg cgatcgcgca atgcctcaaa tccggcttgt ggatcgtcaa ataatttagc
     8461 aaagtcttgc tgaagggatt catagttgag ttccggacgg ttgagagagt tgagatagtt
     8521 gcgaatagag tcaaaaatct gatcaatcac cgattgcacc ctttgctgga cttgccgtga
     8581 ttgttcaatt atcgagttac caacagactc aatctgatca acaatgcggt ttgcttcttc
     8641 ttctgagata tcctcacgct cagataacaa agcaactagt gtagaacggt caaatttgga
     8701 gaagcgctca cctaaagaag caactccggt gcgaggcgag gacaacaata atcgtaaatc
     8761 ccgcttaata ccttctgggt taagttcttc tttcctggtg tggcgcaggt agtcttctag
     8821 attcgcttca aaatccaaaa ctttttgagt ggcacgggtt gccaaacgtc ccggtgcttg
     8881 gacaattcga ctaatcgctt cttgtacagc atctatgatg cgattggctt gttcttcact
     8941 caaatctccg cgctgggcta gcagtttgac taaagtttcc cgatcaattt gagagaggcg
     9001 atcgcgtaat gcatttatac cttcttgagg attttgtagc aatttggtca aatcttgttg
     9061 aataccttct gggttaagtt cttcaagatt ggtattacgc agatactcag caatcgttct
     9121 tgttgtttgc tcatactgct ctttcgcctt atctgcaact ttctgcggcg cttgcaaaat
     9181 gttatctctc actgcttcca attggtcaag aatttgatta acttgttctt catccaaatc
     9241 ttgacgctga ctcagcaatt tcgctaatgt atcacggtca aattgcgata ggcgagtgcg
     9301 taaaagacta attcccgctt gtgggtcttc tagcaaaacc ctaaaatcac gcttgatgcc
     9361 ttcaggattg agttcttctt tgccagtatt cctgagataa tcttctaccc tttgccgtag
     9421 ttcatcagct ttggcttttg cttgttcttg cagttctctt gcacggttaa ggatatggtc
     9481 acggctgagt tcgagttgac caataatatt gttagcttcc tcttcattga agtctccgcg
     9541 ttgctggagg agttgcacaa acacatcgcg attgagttcc ccaaagcgat cgcttaaatc
     9601 ttcaacacca gcctcaggat cttccaaaag ccttgcaaac tcccgctcaa tactttctaa
     9661 attcagttct tctttggggg tagaacgcag atactcttca atacgagtgc ggaaatcttg
     9721 gaattgtttt cgtgttgcac tttgctgtac agtttctaaa acttccaagc gaacactttc
     9781 taattgttcg acaatttctt ttaccctcgc ttcattgatg tcgtctcgtt gtgttagcaa
     9841 gttgttaaag tactcagcat tgagttcctc taattgccgt ttcactgttg acgggtctgc
     9901 atttggatca tagatgatgt ctttgaactc atctttgatg gtaatgcggt tgaaatgcca
     9961 ggggaaagaa ttccgtatgt aattttctac atccgtctta attgtgttat ctgatgacgc
    10021 tggtaattgc ttggctattt gttctcttgt ttgatctcca agatgtttta actgcgaagt
    10081 aattttgtcg atatctaaat cttggacttt ttctttgagc ttgggcaata cagatgtgac
    10141 tttatctaca tcaacattag aaaaatctac tctattaaga actgctggca cagcagcgct
    10201 taagccatat tgaataagtg gctgtatgcc tccgcctcca ttagcatcat tacttttact
    10261 accattgcct ccaactgtaa ccagttcttg aagccgttca cccaagtgct cagaatttag
    10321 ttccctagaa gtggctgacc aaagaaaatc aatcacccga tctgtcggat tttgccgatt
    10381 aacaacttct ttccaagcat cttcaagttg atcagcaata cgattgatat cttctttaga
    10441 aaagtctgtg cgactgctga gcaaatcaac aaatgtctgg cgattgatat ttttcagcac
    10501 atcgctatcg ccaagagact gcagatttgc atcactcaga agccgagcaa attgattgcg
    10561 aacttcttgg agatctaatt ttggcagtgg gagtgaagcc aaagaacttt gtaacgcatt
    10621 tctgatactg ttagggtcta aacctgaagt aagttcacga cgaacagcag cggtgatgtc
    10681 ctcaacagtg gaaaccatct gtgctttggc tgcgttagca cttatggcag cagtcgctgt
    10741 acccattaat ccttgaacac cagaagttgc agtgctaaca agagcaccag tgacggaacc
    10801 tagtgctgat gaacccatcc acactaggac taaaaagtag gtagaccaaa tcacaacacc
    10861 aataattgct cctaaaaacc cactattaat caagctaagc ttcactgcca gaaaactagc
    10921 acaaaagagt g
//
