LOCUS       c00660_3300027..        7556 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027965.a:Ga0209062_1009735.
ACCESSION   c00660_3300027..
VERSION     c00660_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 03:16:34
            Original ID  :: 3300027965.a:Ga0209062_1009735
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7556
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7556
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:6499]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..6499
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..7556
                     /SMILES="NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7556
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..1487)
                     /NRPS_PKS="Domain: Condensation_LCL (72-372). E-value:
                     5.8e-117. Score: 381.7. Matches aSDomain:
                     nrpspksdomains_ctg660_1_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     448.2; E-value: 6.2e-136)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg660_1"
                     /sec_met_domain="Condensation (E-value: 4.1e-85, bitscore:
                     274.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKIVEFLSHLRSLDIQISVDGEKLRCNAPEAVLTAELRAEIQQRK
                     VEILEFLKAANYQSTHASTPLVPIARNRHLPLSFAQQRLWFLDQLVPNNPFYNVPAAFR
                     LTGSLNLGALKQTFQEIVQRHEALRTTFMVVDGQPVQVIHSRLKISLPVTDLRHLSPAE
                     RETQTRLLTIEEAQRPFNLSTGPLLRVTLLQLDAAEHVLVLNMHHIVSDGWSIGVLIRE
                     IVALYTANACDRPSPLPQPTIQYADFAYWQRQWLQGEVLESQLAYWRQHLAGISMLNLP
                     TDRPRSPVPTYRGARQLLKLPKSLSKDLLALSQKEGVTLFMTLLAAFQLLLYRYTQQED
                     ITVGSPIANRNRSEIEGLIAFFVNSLVLRTNFSGNPTFLELLSRVKEVALQAYAHQDLP
                     FEKLVEELHPERNLNQNPLFQVVFALQNAPVSALELPGLTLKPLQFDIETTRFDLELHL
                     WEPEAQNGLWVDSSEGISGFVIYNTDLFDDATVTRMI"
     CDS_motif       complement(78..104)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_1_0007"
                     /evalue="1.30E+00"
                     /label="C1_starter_004-017"
                     /locus_tag="ctg660_1"
                     /protein_end="470"
                     /protein_start="461"
                     /score="2.8"
                     /tool="antismash"
                     /translation="EAQNGLWVDS"
     CDS_motif       complement(213..332)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_1_0006"
                     /evalue="3.00E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg660_1"
                     /protein_end="425"
                     /protein_start="385"
                     /score="77.5"
                     /tool="antismash"
                     /translation="KEVALQAYAHQDLPFEKLVEELHPERNLNQNPLFQVVFALQ"
     aSDomain        complement(372..1271)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg660_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="5.80E-117"
                     /label="ctg660_1_Condensation_LCL.1"
                     /locus_tag="ctg660_1"
                     /protein_end="372"
                     /protein_start="72"
                     /score="381.7"
                     /tool="antismash"
                     /translation="RHLPLSFAQQRLWFLDQLVPNNPFYNVPAAFRLTGSLNLGALKQT
                     FQEIVQRHEALRTTFMVVDGQPVQVIHSRLKISLPVTDLRHLSPAERETQTRLLTIEEA
                     QRPFNLSTGPLLRVTLLQLDAAEHVLVLNMHHIVSDGWSIGVLIREIVALYTANACDRP
                     SPLPQPTIQYADFAYWQRQWLQGEVLESQLAYWRQHLAGISMLNLPTDRPRSPVPTYRG
                     ARQLLKLPKSLSKDLLALSQKEGVTLFMTLLAAFQLLLYRYTQQEDITVGSPIANRNRS
                     EIEGLIAFFVNSLVLRTNFS"
     aSModule        372..1271
                     /domains="nrpspksdomains_ctg660_1_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg660_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(381..470)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_1_0005"
                     /evalue="7.10E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg660_1"
                     /protein_end="369"
                     /protein_start="339"
                     /score="50.5"
                     /tool="antismash"
                     /translation="DITVGSPIANRNRSEIEGLIAFFVNSLVLRT"
     CDS_motif       complement(720..758)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_1_0004"
                     /evalue="7.90E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg660_1"
                     /protein_end="256"
                     /protein_start="243"
                     /score="18.3"
                     /tool="antismash"
                     /translation="QYADFAYWQRQWLQ"
     CDS_motif       complement(807..872)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_1_0003"
                     /evalue="7.60E-13"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg660_1"
                     /protein_end="227"
                     /protein_start="205"
                     /score="40.8"
                     /tool="antismash"
                     /translation="MHHIVSDGWSIGVLIREIVALYT"
     CDS_motif       complement(1092..1205)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_1_0002"
                     /evalue="3.50E-20"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg660_1"
                     /protein_end="132"
                     /protein_start="94"
                     /score="64.4"
                     /tool="antismash"
                     /translation="PFYNVPAAFRLTGSLNLGALKQTFQEIVQRHEALRTTFM"
     CDS_motif       complement(1224..1256)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_1_0001"
                     /evalue="6.60E-04"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg660_1"
                     /protein_end="88"
                     /protein_start="77"
                     /score="12.0"
                     /tool="antismash"
                     /translation="SFAQQRLWFLDQ"
     CDS             complement(1918..2403)
                     /locus_tag="ctg660_2"
                     /transl_table=11
                     /translation="VLIVFNSSPLIFLARLGFLNTFVDSANEFYLPMFVAEEISAKSDK
                     ASQSVQQLIDLVKITPRAIKLTFLANSLNARLGLGESEAIALGIELPCDYIILDDNAAR
                     KEAIRLGLQVKGTLAVIKKLQADGKITIDSLEQLYQQLVAINFRVKRSLFDSIFEDK"
     CDS             complement(2409..2648)
                     /locus_tag="ctg660_3"
                     /transl_table=11
                     /translation="MTNREALRSVAAEVQLFNDIEQKETFLFVLGALFSRVISLKKAAE
                     MMEMEPNIFLELLDIMGLEFSYLTSQDVALEKDW"
     CDS             complement(2868..3044)
                     /locus_tag="ctg660_4"
                     /transl_table=11
                     /translation="MGIAHAMNSLMESLIWSFYTDHFADAPEFTELGEPAYNEYLDAVL
                     HKTCQHLFGRAVV"
     CDS             complement(3206..6499)
                     /NRPS_PKS="Domain: Condensation_LCL (8-312). E-value:
                     4.1e-111. Score: 362.5. Matches aSDomain:
                     nrpspksdomains_ctg660_5_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (491-891). E-value:
                     9.3e-110. Score: 358.7. Matches aSDomain:
                     nrpspksdomains_ctg660_5_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1006-1074). E-value: 8.5e-30.
                     Score: 94.5. Matches aSDomain:
                     nrpspksdomains_ctg660_5_PCP.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     435.4; E-value: 4.8e-132)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg660_5"
                     /sec_met_domain="Condensation (E-value: 9e-74, bitscore:
                     236.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.8e-117, bitscore:
                     379.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.3e-21, bitscore:
                     64.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSEEVFIFPLSFAQQRLWFIDQLIPDNTIYNVPTVIRLTGSLKI
                     AALERTLKEIVRRHETLRTTFKVLNGQPLQAIACSQTIPLNVLNLQTLPVDEREAEAKR
                     ILAAEIERPFDLSTGPLLRVMLLVLSARESILVLNMHHIICDDWSIGVLIQELGILYAA
                     FAHNKPSPLPELPVQYADFTHWQREWLQATDVNGVSPLQTQLTYWRQQLKDIAMLHLPT
                     DRPRSQIQNYQGATEFLEIPQTLTNALQALSQQESATLFMTLLAAFQTLLYRYTYQADI
                     AVGSPIANRNRSEIEGLIGFFVNSLVLRTNLSGNPTFRELLRRVRAVTLGAYGHQDLPF
                     ERLVEELQPERNLGYHPLFQVVFAFQNAPMPALTLPGLIPSFINIDFKKTRFDLELYLW
                     RASEDFRSLWGTNWNSSDGIRGVIVYNTDLFDKTTITRMIEHFQTLLSGIVENPNEHIS
                     QLPLLSAQELNRILVEWNHNHVDYPQDKCIHQLFENQVEKNPDSTAISFENQQITYREL
                     NNYSNKLAHHLQRVGVTSEVLVGICIEQSVEFIVGLLGILKAGGTYVPLDPRYPQERLK
                     FILKDAQVSILIIQEKFIKHFEKFLHPIICLDEMKEILAQESEENLKSSVISANLAYVI
                     YTSGSTGKPKGVSVSHKAVIRLVCNTNYITLESHDKIAQAANTSFDAVTFEIWGALLNG
                     AQLVGINKDIALSPHEFAFQLQQKSITVLFLTTALFQQITRDIPQAFSSLRYLLFGGES
                     VDPRWVKKVIKHGPPQHLIHVYGPTEGTTFSSYYYAKEISESATSIPIGCPIANTQIYL
                     LDPYLQPLPIGVVGELYIGGDGLARGYINRPELTAECFISNPFVYKLGSRLYKTGDLGR
                     YLPNGNIEFLGRIDNQVKIRGFRVELGEIEAVLNLHPVVKETVVLFNEDIPDDKYLIAY
                     IIPNQSHKSTQDTQTLVFLVGQFLKENLPEYMVPRAYIILESLPLTPNGKVDRRALPTP
                     DTFTFTQPDYVAPRSQVEGLLVEIWAQVLGKKQVGTRDHFFELGGHSLLATQLVSRIRD
                     TFQIDLSVRNLFEAPTVEQLARHIDTMSWAKKGLSQNRTTKKEREEVEF"
     aSDomain        complement(3278..3481)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg660_5_PCP.1"
                     /evalue="8.50E-30"
                     /label="ctg660_5_PCP.1"
                     /locus_tag="ctg660_5"
                     /protein_end="1074"
                     /protein_start="1006"
                     /score="94.5"
                     /tool="antismash"
                     /translation="EGLLVEIWAQVLGKKQVGTRDHFFELGGHSLLATQLVSRIRDTFQ
                     IDLSVRNLFEAPTVEQLARHIDTM"
     aSModule        3278..6475
                     /complete
                     /domains="nrpspksdomains_ctg660_5_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg660_5_AMP-binding.1"
                     /domains="nrpspksdomains_ctg660_5_PCP.1"
                     /locus_tags="ctg660_5"
                     /monomer_pairings="ile -> ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3401..3442)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0011"
                     /evalue="4.90E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg660_5"
                     /protein_end="1033"
                     /protein_start="1019"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="KKQVGTRDHFFELGG"
     CDS_motif       complement(3797..3862)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0010"
                     /evalue="1.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg660_5"
                     /protein_end="901"
                     /protein_start="879"
                     /score="39.5"
                     /tool="antismash"
                     /translation="FLGRIDNQVKIRGFRVELGEIEA"
     aSDomain        complement(3827..5026)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg660_5_AMP-binding.1"
                     /evalue="9.30E-110"
                     /label="ctg660_5_AMP-binding.1"
                     /locus_tag="ctg660_5"
                     /protein_end="891"
                     /protein_start="491"
                     /score="358.7"
                     /specificity="consensus: ile"
                     /tool="antismash"
                     /translation="FENQVEKNPDSTAISFENQQITYRELNNYSNKLAHHLQRVGVTSE
                     VLVGICIEQSVEFIVGLLGILKAGGTYVPLDPRYPQERLKFILKDAQVSILIIQEKFIK
                     HFEKFLHPIICLDEMKEILAQESEENLKSSVISANLAYVIYTSGSTGKPKGVSVSHKAV
                     IRLVCNTNYITLESHDKIAQAANTSFDAVTFEIWGALLNGAQLVGINKDIALSPHEFAF
                     QLQQKSITVLFLTTALFQQITRDIPQAFSSLRYLLFGGESVDPRWVKKVIKHGPPQHLI
                     HVYGPTEGTTFSSYYYAKEISESATSIPIGCPIANTQIYLLDPYLQPLPIGVVGELYIG
                     GDGLARGYINRPELTAECFISNPFVYKLGSRLYKTGDLGRYLPNGNIEFLGRIDNQVKI
                     RG"
     CDS_motif       complement(3950..4039)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0009"
                     /evalue="3.20E-19"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg660_5"
                     /protein_end="850"
                     /protein_start="820"
                     /score="60.9"
                     /tool="antismash"
                     /translation="PIGVVGELYIGGDGLARGYINRPELTAECFI"
     CDS_motif       complement(4547..4606)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0008"
                     /evalue="1.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg660_5"
                     /protein_end="651"
                     /protein_start="631"
                     /score="32.8"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVSVSHK"
     CDS_motif       complement(4799..4840)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0007"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg660_5"
                     /protein_end="567"
                     /protein_start="553"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LGILKAGGTYVPLDP"
     CDS_motif       complement(5405..5524)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0006"
                     /evalue="6.40E-25"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg660_5"
                     /protein_end="365"
                     /protein_start="325"
                     /score="79.7"
                     /tool="antismash"
                     /translation="RAVTLGAYGHQDLPFERLVEELQPERNLGYHPLFQVVFAFQ"
     aSDomain        complement(5564..6475)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg660_5_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="4.10E-111"
                     /label="ctg660_5_Condensation_LCL.1"
                     /locus_tag="ctg660_5"
                     /protein_end="312"
                     /protein_start="8"
                     /score="362.5"
                     /tool="antismash"
                     /translation="FPLSFAQQRLWFIDQLIPDNTIYNVPTVIRLTGSLKIAALERTLK
                     EIVRRHETLRTTFKVLNGQPLQAIACSQTIPLNVLNLQTLPVDEREAEAKRILAAEIER
                     PFDLSTGPLLRVMLLVLSARESILVLNMHHIICDDWSIGVLIQELGILYAAFAHNKPSP
                     LPELPVQYADFTHWQREWLQATDVNGVSPLQTQLTYWRQQLKDIAMLHLPTDRPRSQIQ
                     NYQGATEFLEIPQTLTNALQALSQQESATLFMTLLAAFQTLLYRYTYQADIAVGSPIAN
                     RNRSEIEGLIGFFVNSLVLRTNLS"
     CDS_motif       complement(5573..5662)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0005"
                     /evalue="2.50E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg660_5"
                     /protein_end="309"
                     /protein_start="279"
                     /score="55.2"
                     /tool="antismash"
                     /translation="DIAVGSPIANRNRSEIEGLIGFFVNSLVLRT"
     CDS_motif       complement(5930..5968)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0004"
                     /evalue="5.50E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg660_5"
                     /protein_end="190"
                     /protein_start="177"
                     /score="18.8"
                     /tool="antismash"
                     /translation="QYADFTHWQREWLQ"
     CDS_motif       complement(6017..6082)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0003"
                     /evalue="3.60E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg660_5"
                     /protein_end="161"
                     /protein_start="139"
                     /score="32.3"
                     /tool="antismash"
                     /translation="MHHIICDDWSIGVLIQELGILYA"
     CDS_motif       complement(6302..6415)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0002"
                     /evalue="6.90E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg660_5"
                     /protein_end="66"
                     /protein_start="28"
                     /score="57.0"
                     /tool="antismash"
                     /translation="TIYNVPTVIRLTGSLKIAALERTLKEIVRRHETLRTTFK"
     CDS_motif       complement(6437..6466)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg660_5_0001"
                     /evalue="2.80E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg660_5"
                     /protein_end="21"
                     /protein_start="11"
                     /score="10.3"
                     /tool="antismash"
                     /translation="SFAQQRLWFID"
     CDS             complement(6610..7287)
                     /gene_functions="other (smcogs) SMCOG1272:TPR
                     repeat-containing protein (Score: 74; E-value: 2e-22)"
                     /gene_kind="other"
                     /locus_tag="ctg660_6"
                     /transl_table=11
                     /translation="MNHIKQALAILGITSILGGIPAVVHAQLPEVSTKLVSFQEYYNQG
                     LQKLKIGNFSSAIQDFNQVVRLNPQYYEGYCLRGLARAQSGDSKTAIADFTLALHLNPN
                     HTEAYNGRGTAYAETGNLPAALADFNQTIKLDPQFEDGYYNLGLANLKLGKHKLAVANF
                     NHALKINANRADTYGNRGLAYYALGDSKHAVKDLQVAARLFQQQGNTEGYQQVQTLIQQ
                     MQR"
ORIGIN
        1 cttatcatcc gggtaacagt agcgtcatca aataaatcag tgttgtaaat gacaaagccg
       61 ctgattcctt ctgaactatc tacccataaa ccattttgag cctctggctc ccacagatga
      121 agctctaaat caaagcgcgt tgtctcaata tcaaattgca aaggtttgag agttaaacct
      181 ggtaattcta gggctgatac aggcgcattt tggagggcaa agactacttg aaaaagtgga
      241 ttctggttca agttccgttc tgggtgtagt tcttctacca gcttttcaaa aggtaaatct
      301 tggtgagcat aagcttgtag cgcgacttct ttaactcgac tcaacaattc cagaaaagtt
      361 ggattccctg agaagttagt acgcaaaact aaactattca caaaaaaggc aatcaatcct
      421 tcaatttcac tgcgattgcg gttggcaata ggtgaaccaa cagtaatatc ttcttgttgt
      481 gtgtaacggt agagtaaaag ttgaaatgct gccagcaaag tcataaacaa ggtgactcct
      541 tccttctggg aaagagctaa aaggtctttg ctcaggcttt ttggtagttt tagtaattgc
      601 cttgcacccc ggtaagttgg aactggcgat cgcggtctat cggtaggtag gttaagcatg
      661 gaaatgccag ccaaatgttg tcgccagtaa gctagctgag attctaaaac ttccccttgt
      721 aaccattggc gttgccagta agcaaaatct gcatattgga ttgtcggttg cggtaggggg
      781 gaagggcgat cgcaagcatt ggctgtatat agtgctacta tttctcgaat cagcacccca
      841 atagaccaac catcagaaac aatatggtgc atatttagca ccaacacatg ctcagctgca
      901 tccaactgta gcagtgtaac tcgcagcagt ggtccagttg ataaattgaa aggtcgttgg
      961 gcttcctcga tagtgagtag tcgtgtttgc gtttcacgtt cggctggtga caaatgccgt
     1021 aaatctgtga ctggtaatga tatttttaat ctggaatgaa tgacctggac tggttgccca
     1081 tcaaccacca taaaggttgt acgtaaagct tcatgacgct gtacaatttc ttgaaaagtt
     1141 tgttttagtg cccctaaatt cagcgaacct gttagacgaa atgcggctgg gacattgtag
     1201 aaaggattgt tgggtactaa ttggtcaaga aaccagagtc gttgttgagc aaacgaaaga
     1261 gggagatgtc tgttgcgagc aataggtaca agaggcgtgg aagcgtgagt ggactgataa
     1321 ttagctgctt taagaaattc aagaatttct actttacgct gttgaatttc tgcccgtagt
     1381 tctgctgtca gaaccgcttc aggggcgtta cagcgtaact tttctccatc cacagaaatc
     1441 tgaatatcta ggctgcgaag atgagataaa aactcaacta tcttcaaaat tacctcccct
     1501 cgcagcagtt gttgtttagt agttattgac taacccagta gttctatcac accgagaaca
     1561 gcacataaat cattcttgag gttgaaaatt tcatgattct agcgagacaa gcgtttgaat
     1621 acctgggaat tggttaaaat ttgcaatctc ctattttcac tgtagtagct gtattaagag
     1681 gcaggtgtaa ttactctcaa tcaggtaatt aaaaacatta tatatgctgt acaattaaga
     1741 attgatactt aaaacgtttg tattctcacc ttaatgcaag cacatcaaaa taaagttttt
     1801 ggagcgttgt gatagtttaa ggagcattaa ggtaaatcgc caaaactatt atcctgccta
     1861 tatttttcgc ttttttagca atttctcaaa tttggaaaaa aatgagtgaa tcgagagtta
     1921 tttgtcttca aagatgctat caaacagcga tcgcttgact ctgaaattaa ttgccactag
     1981 ctgttgataa agttgctcta agctatcaat ggtaatttta ccatctgcct gaagtttctt
     2041 gatgactgcg agagtcccct tcacttgcag ccctaaccga attgcttcct ttcgagccgc
     2101 gttgtcatct aaaataatgt aatcacatgg cagttcaata cctaaagcaa tggcttctga
     2161 ctctcctaaa cctagtcgtg catttagact gttagctaaa aaagttagct taatcgctct
     2221 gggtgttatc ttaactaaat caatcaactg ttgcacggat tgactagctt tgtccgattt
     2281 agcagaaatt tcctctgcca caaacattgg tagataaaat tcattggcag agtcaacaaa
     2341 agtattgaga aatcctagac gcgctagaaa aattaatggg gatgagttaa agactattaa
     2401 cacattcctt accaatcctt ttcaagtgca acatcttgtg aagttagata ggaaaactct
     2461 aaacccatga tgtctaataa ctctaaaaag atattgggtt ccatttccat catttctgct
     2521 gcttttttta agctaatcac tcgcgaaaat aatgctccaa gcacaaacag aaaagtttct
     2581 ttctgctcaa tatcattgaa caattgaact tctgccgcca cgcttctcag tgcttctcta
     2641 ttagtcataa atctgttaga taagtttaag agtaatctta cacttaaaag ccttcagaag
     2701 aaagcagatg ctcttggttt tcaacttgtc cctaaaactg aagataaatc aaacacacac
     2761 ttttctcaaa cctctgctac ataggctttg cagcatatat ttcttgaaag agggatagaa
     2821 tacaattttg tttgtagagt tgagcaactg ttcggcttta acaccaacta aactactgcc
     2881 ctgccaaaca aatgctgaca agttttgtgg aggacagcat ctaggtattc attataggca
     2941 ggctcaccca attcagtgaa ttctggagca tccgcaaaat gatccgtata aaatgaccat
     3001 attaagctct ccatcaatga gttcatagcg tgtgctatcc ccatattggg agataaaatc
     3061 ctcaaagctc ggtggtttag gtggggtgta ggtcataggt cgtgttgctt cggaagtagc
     3121 ttaattataa aagacctacg tcggaggagt aagacatgtg gcataggcag aaaacaacag
     3181 tttgtagttt ggtagagccc tcagatcaaa attctacttc ttctcgttct ttttttgtcg
     3241 ttctattctg gctcaaacct ttttttgccc aagacattgt atcgatgtgt ctagcaagtt
     3301 gttcaacagt cggtgcttca aacaaattac gtacagataa atctatttgg aaggtatccc
     3361 gtattcttga aactaactga gtcgctagta gagaatgacc acccagttca aagaaatgat
     3421 cacgggtacc tacttgcttt tttcccaaaa cctgagccca aatttctaca agcaatcctt
     3481 caacttgtga gcgtggtgcc acataatctg gttgagtaaa agtaaatgtg tcaggtgtgg
     3541 gtaaagcacg gcgatccact ttgccgttgg gtgttagtgg taaagattcc agtattatat
     3601 aagctcttgg caccatgtat tctggtaagt tttctttgag aaattgtccg actaaaaaca
     3661 ctaatgtttg tgtatcttgt gttgatttat gtgattgatt aggaataata taagctatca
     3721 aatacttatc atcaggtata tcttcattaa aaagaactac tgtttctttc actactggat
     3781 gtaaattcaa caccgcttca atctcaccca attcgactcg gaatccacga atttttactt
     3841 gattgtcaat gcggcctaaa aattcaatat taccatttgg taaataacga cctaaatcac
     3901 ctgttttgta aagacgtgag ccaagcttat aaacaaaagg attagaaatg aaacattcgg
     3961 cagttaattc agggcggttg atatatcctc gtgccaatcc atcaccccca atgtacaatt
     4021 caccaacaac gccaattggt aaaggttgta aatagggatc tagtagataa atttgtgtgt
     4081 ttgcaattgg gcaaccaatg ggaatagatg tagctgattc tgaaatttct tttgcatagt
     4141 aataagaaga aaatgttgta ccctctgtag ggccataaac atgaattaag tgttggggtg
     4201 gaccatgttt aataaccttt ttgacccatc ttggatcaac agactcgcca ccaaatagca
     4261 agtatcttaa tgaagaaaaa gcttgtggga tatctctagt gatttgctgg aataaagcag
     4321 ttgtcaaaaa taggacagtg atactttttt gctgtagctg aaatgcaaac tcatgaggtg
     4381 aaagggctat atctttattg atgccaacga gttgagcccc gttcagtagc gctccccaaa
     4441 tctcgaaagt aacagcatca aaagaagtgt tggcagcttg cgcaattttg tcatgagatt
     4501 ctaatgttat atagttggtg ttacatacca acctaatgac agctttatgg ctgacactta
     4561 cacccttagg ttttcccgta gaaccagagg tgtaaatgac atacgctaaa ttagcactaa
     4621 taacactgct tttgaggttt tcttcgcttt cttgagcaag aatttccttc atttcatcca
     4681 agcaaataat tggatgtaag aatttctcaa aatgcttgat aaatttttct tgtattatca
     4741 atattgaaac ttgtgcatct ttaagtataa actttaggcg ttcttgtgga tatctagggt
     4801 ctaatggaac atacgttcct cctgctttga gaattcccag caatcccaca atgaattcta
     4861 cagactgttc aatacaaata cctactaaaa cttcagaagt aacacctact ctttgtaaat
     4921 gatgcgctag tttattacta taattattta actctcgata agtgatttgc tgattctcaa
     4981 aacttattgc tgtagaatca ggattcttct ctacctgatt ttcaaacaac tgatgaatac
     5041 atttatcttg agggtaatct acatgattgt ggttccattc tactaatatt cgatttagct
     5101 cctgtgcact taatagtggt aactgggaaa tatgttcgtt tggattttca acaatgcctg
     5161 atagcagtgt ttgaaaatgt tctatcattc gggtaattgt cgttttgtca aacaaatctg
     5221 tgttgtaaac aattacacct ctaataccat cagaagaatt ccagttagta ccccataaac
     5281 ttctaaagtc ttcagaagct ctccataggt acaactctaa atcaaaacgt gtttttttaa
     5341 aatcaatatt tataaagcta ggtattaatc ctggcagtgt tagtgctggc attggtgcgt
     5401 tttgaaacgc aaacacgact tgaaatagag gatgataacc taaatttctc tctggttgta
     5461 attcttctac tagcctttca aaaggcaaat cttgatggcc ataagctcct agtgtgactg
     5521 cccgtaccct acgaagcagt tcccgaaaag taggatttcc agataagttg gtacgcaata
     5581 ctaagctatt gacaaaaaaa ccaatgagcc cttcaatttc acttcggttg cggttagcaa
     5641 ttggcgaacc tacagcaata tctgcttgat atgtataacg atagagcagt gtctgaaagg
     5701 ctgcgagtag agtcataaat aaagtagcac tttcttgctg agaaagtgct tgaagtgcat
     5761 tagttagcgt ttgcggtatc tctaaaaatt ctgttgctcc ttggtagttt tgtatttgcg
     5821 atcgcggtct atcggtaggc agatgcaaca tggcaatatc ttttaattgc tgtcgccagt
     5881 aggttaattg ggtttgtagg ggtgagacac cattgacatc agtagcttgc agccattcgc
     5941 gttgccagtg agtaaagtcg gcatactgaa caggtagttc tggtaggggt gaaggcttat
     6001 tgtgggcaaa agctgcatac aggattccca attcctgaat cagcacccca atagaccaat
     6061 catcacagat aatatggtgc atattcagca ctaggataga ttctctcgcc gagagaacaa
     6121 gtagcatgac tcgcagcaat ggccctgtag acaaatcaaa tggacgttct atctctgcag
     6181 caagaatgcg ttttgcttca gcctcgcgtt catcgactgg caatgtctgg aggtttaaca
     6241 cgttaagggg tattgtttgg ctgcaggcga tcgcttgtag gggttgtcca tttaatacct
     6301 taaatgtggt gcgtaaggtt tcgtgacgac gtacaatttc cttcaatgtc cgctctagtg
     6361 cagctatttt cagcgagcct gttaaacgga tgactgtggg tacattataa atagtgttgt
     6421 cggggatcaa ctggtcgata aaccacagcc tttgttgggc aaaagatagg gggaaaataa
     6481 aaacttcttc agaggacatc acatgaactt acgtatacta gggggcatgg ggaatagggg
     6541 catagggcat agaaaaatag tctattcatg ccataaatga gatagggcgg gaacgttatc
     6601 ttaaattgct tatcgctgca tctgctggat gagggtttgt acttgttgat aaccttcagt
     6661 gtttccttgt tgctgaaaga gtcttgctgc cacttgtaga tctttaacag cgtgtttact
     6721 gtctcctaga gcatagtaag caagcccccg gttaccataa gtatcagccc gattggcatt
     6781 gattttaagg gcatggttaa agttggcaac tgccagcttg tgctttccta atttaaggtt
     6841 ggcaagtcca agattatagt agccatcttc aaactgtgga tctagtttga ttgtctggtt
     6901 gaagtcggca agcgctgcag ggagatttcc tgtctccgca taagctgttc ctcttccgtt
     6961 gtaagcttct gtatggttgg gattaaggtg tagtgccaaa gtaaaatcag cgatcgctgt
     7021 tttagaatct cctgattgtg ctcgtgccag acctcggaga cagtagcctt cataatattg
     7081 aggattcaat cgtactacct gattgaaatc ctgaatagca ctgctgaaat tgccgatttt
     7141 aagtttttgt aacccctgat tataatattc ttggaaactg actagcttag ttgatacttc
     7201 tggaagttgt gcatgaacca cagcaggtat tcctcctaag atactcgtta ttcccaaaat
     7261 tgcgagcgcc tgcttgatat ggttcatagc tttacctcct aaagcaatgt tttccttacc
     7321 cttattctaa tgaagcaacg cacgtatgca acctgtcatc cagcaccgga gaaaacaatt
     7381 tgctaaacgt actcaacaga tcaatgctta ttagataaca gctactaacg cttgccatta
     7441 acttcaaatc agcactcagc ctaaatcatt tcttgccagt gatgtacaag cgcttgctgc
     7501 agcagacatc agctttgctg tagagggaat tgatattgct ttagagacag cagata
//
