LOCUS       c00662_3300027..       10397 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027965.a:Ga0209062_1006673.
ACCESSION   c00662_3300027..
VERSION     c00662_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 03:16:34
            Original ID  :: 3300027965.a:Ga0209062_1006673
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10397
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10397
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:2248](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2..2248)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..10397
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10397
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     aSDomain        complement(2..874)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg662_1_AMP-binding.1"
                     /evalue="6.00E-78"
                     /label="ctg662_1_AMP-binding.1"
                     /locus_tag="ctg662_1"
                     /protein_end="749"
                     /protein_start="458"
                     /score="253.9"
                     /specificity="consensus: thr"
                     /tool="antismash"
                     /translation="FEEIVCNYPQHIAVQFENVTLTYTELNQKANRLAHHLQSLGVKPE
                     TRVGLCLERSGNMVVAILGILKAGGAYVPLDPNYPASRLQFILEDSGVSLLIVEPLISQ
                     FLDTDIEVFSWESIEGELAHYPDLPLQISLQPQHPAYIIYTSGSTGTPKGCVVTHANVM
                     RLMRSTEPWFGFNANDVWTLFHSFAFDFSVWELWGALLYGGKVIVVPFWLSRSPAAFWE
                     LLIQEKVTVLNQTPSAFQQLIRADEANIAQLALRYVIFGGEALNLESLRPWFERYGDQT
                     PRLVNMYGIT"
     aSModule        2..2242
                     /domains="nrpspksdomains_ctg662_1_Condensation_Starter.1"
                     /domains="nrpspksdomains_ctg662_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg662_1"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS             complement(2..2248)
                     /NRPS_PKS="Domain: Condensation_Starter (2-297). E-value:
                     6.8e-73. Score: 237.3. Matches aSDomain:
                     nrpspksdomains_ctg662_1_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (458-749). E-value: 6e-78.
                     Score: 253.9. Matches aSDomain:
                     nrpspksdomains_ctg662_1_AMP-binding.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     244.6; E-value: 3.9e-74)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg662_1"
                     /sec_met_domain="Condensation (E-value: 3.3e-50, bitscore:
                     160.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-75, bitscore:
                     242.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTKFPLSINQLDIYVDQLRWSEGSHLNIGAIGTIVGTLDTQVFN
                     CALNQILRCHPGLRVRIYEFEGKPFQIIAEHQDTRLTLVDFSNYDNSEELAQEYIESDF
                     QKPFHFGQDSSLACFQLIRVSSQKHLWYGKFHHIIVDGWGTSLLFKEVIYTYNQILHKS
                     EFQQAERDLTLIDYLEEETTYLQSKSFESDRNYWTQRLQDVSPKIFPEITKPQLLGGRK
                     AIYIKRQQYNQVESICKEIQSNAFHFILSILLIYLTKRYRQKDLVIGLPILNRSKKAYK
                     EAIGLFVSMLPFRIEINSNETLADILQTVRSLLRQDYRHQRFPLGEMKRIAESHQNLFD
                     ITLSYEKHDYSEAFEDTHTICVPLYSGQQKTPLAIYVREFDHQSDIKIDFDYNLAYFDA
                     ETIEQMVTHFQKLFNDALENLDKQIFDISLLSTEARQRFFQKPLISANLSPTPETLVTA
                     FEEIVCNYPQHIAVQFENVTLTYTELNQKANRLAHHLQSLGVKPETRVGLCLERSGNMV
                     VAILGILKAGGAYVPLDPNYPASRLQFILEDSGVSLLIVEPLISQFLDTDIEVFSWESI
                     EGELAHYPDLPLQISLQPQHPAYIIYTSGSTGTPKGCVVTHANVMRLMRSTEPWFGFNA
                     NDVWTLFHSFAFDFSVWELWGALLYGGKVIVVPFWLSRSPAAFWELLIQEKVTVLNQTP
                     SAFQQLIRADEANIAQLALRYVIFGGEALNLESLRPWFERYGDQTPRLVNMYGIT"
     CDS_motif       complement(398..457)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg662_1_0006"
                     /evalue="1.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg662_1"
                     /protein_end="617"
                     /protein_start="597"
                     /score="33.1"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGTPKGCVVTHA"
     CDS_motif       complement(647..688)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg662_1_0005"
                     /evalue="2.00E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg662_1"
                     /protein_end="534"
                     /protein_start="520"
                     /score="20.7"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLDP"
     CDS_motif       complement(1214..1309)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg662_1_0004"
                     /evalue="2.90E-09"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="ctg662_1"
                     /protein_end="345"
                     /protein_start="313"
                     /score="29.5"
                     /tool="antismash"
                     /translation="LRQDYRHQRFPLGEMKRIAESHQNLFDITLSYE"
     aSDomain        complement(1358..2242)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg662_1_Condensation_Starter.1"
                     /domain_subtype="Condensation_Starter"
                     /evalue="6.80E-73"
                     /label="ctg662_1_Condensation_Starter.1"
                     /locus_tag="ctg662_1"
                     /protein_end="297"
                     /protein_start="2"
                     /score="237.3"
                     /tool="antismash"
                     /translation="TKFPLSINQLDIYVDQLRWSEGSHLNIGAIGTIVGTLDTQVFNCA
                     LNQILRCHPGLRVRIYEFEGKPFQIIAEHQDTRLTLVDFSNYDNSEELAQEYIESDFQK
                     PFHFGQDSSLACFQLIRVSSQKHLWYGKFHHIIVDGWGTSLLFKEVIYTYNQILHKSEF
                     QQAERDLTLIDYLEEETTYLQSKSFESDRNYWTQRLQDVSPKIFPEITKPQLLGGRKAI
                     YIKRQQYNQVESICKEIQSNAFHFILSILLIYLTKRYRQKDLVIGLPILNRSKKAYKEA
                     IGLFVSMLPFRIEIN"
     CDS_motif       complement(1367..1456)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg662_1_0003"
                     /evalue="5.90E-10"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg662_1"
                     /protein_end="294"
                     /protein_start="264"
                     /score="31.5"
                     /tool="antismash"
                     /translation="DLVIGLPILNRSKKAYKEAIGLFVSMLPFRI"
     CDS_motif       complement(1781..1846)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg662_1_0002"
                     /evalue="2.70E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg662_1"
                     /protein_end="156"
                     /protein_start="134"
                     /score="26.3"
                     /tool="antismash"
                     /translation="FHHIIVDGWGTSLLFKEVIYTYN"
     CDS_motif       complement(2057..2167)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg662_1_0001"
                     /evalue="9.90E-06"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg662_1"
                     /protein_end="64"
                     /protein_start="27"
                     /score="18.2"
                     /tool="antismash"
                     /translation="NIGAIGTIVGTLDTQVFNCALNQILRCHPGLRVRIYEF"
     CDS             complement(2654..3067)
                     /locus_tag="ctg662_2"
                     /transl_table=11
                     /translation="MLERLLGLAISIRAQISDGFCVTGNTGSDSQDQSTLHQVVHHRDL
                     RRHHCRVVVGERKHAGTEGDRRARIGEIRNESEARGDRLGRVDEMLADEGLAVAEPISK
                     HDRFAILAKNVPIRTGRRVDGLDEESELQGVLH"
     CDS             complement(3182..3748)
                     /locus_tag="ctg662_3"
                     /transl_table=11
                     /translation="MRGPSDPGPDLVRHELHGAPGERWIGPVVARVEQCTERADLVAEC
                     KNLVRNALRGSRDYETLNAPLRREIGIRLVGKVAHDVQRAGLRELGPHDVEVEVVRAVL
                     TMHVAMCRSLVIGHENAARHAPPGSICTEARRSPAFHVVLNVGPDDVRTHVGRRDSGPA
                     ARSRDVRSLSARSDRGDGDGRMGLL"
     CDS             4321..4830
                     /locus_tag="ctg662_4"
                     /transl_table=11
                     /translation="MSVNLTVDRNITNVIQYQIPNLTLLPSSKQVTRITLNQLKLDIAK
                     LEKYLQEKVEEKTKQEQKALKEKIEKGIQELETIAEKINSLSTEIEALMIQFKEIAVEV
                     NRNYHLIQLPPFLRQIKSDKSKLNCWRPLNIWDVHSSSIPTVVRRGAKFILTVKMVDLF
                     NAERDK"
     CDS             4898..5119
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009:mbtH-like protein (Score: 91.6; E-value:
                     3.3e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg662_5"
                     /transl_table=11
                     /translation="MKNNEQQNNSIYLVVVNQEEQYSIWPKWKKEIPLGWRTVGKEGSK
                     EECLAYIEEVWTDMRPLSLRKAMAEKQT"
     CDS             5148..5318
                     /locus_tag="ctg662_6"
                     /transl_table=11
                     /translation="MKEYQIGFARALIILIYFYVMSLCMADSVYVIIKSIKTQLCVSHC
                     TPSSLIINNEL"
     CDS             5315..6097
                     /NRPS_PKS="Domain: Thioesterase (22-248). E-value: 9.2e-53.
                     Score: 171.7. Matches aSDomain:
                     nrpspksdomains_ctg662_7_Thioesterase.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 281.3; E-value: 7.8e-86)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg662_7"
                     /transl_table=11
                     /translation="MIAELKRESWVSFPKPNPQASLRLFCFPYAGGKAVSFRGWEKSLL
                     NTVEVCPIELPGRGTRLMEKPFTHFSLLIPTITQALIPYLDKPFAFFGHSMGAIISFEV
                     ARLLRKKYRLSPVHLFISGRGAPQVPIEIKPIHNLPKPAFCQELRRLNGTPEEVLENDE
                     LMELLLPMLRADFALIENYVYTDERPLDCPISVFGGQQDYKVSGDRLQAWIEQTTADFS
                     MQMFPGDHFFLHSAQQLLLQTLSQKLHQLTYKYPCITI"
     aSDomain        5381..6058
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg662_7_Thioesterase.1"
                     /evalue="9.20E-53"
                     /label="ctg662_7_Thioesterase.1"
                     /locus_tag="ctg662_7"
                     /protein_end="248"
                     /protein_start="22"
                     /score="171.7"
                     /tool="antismash"
                     /translation="RLFCFPYAGGKAVSFRGWEKSLLNTVEVCPIELPGRGTRLMEKPF
                     THFSLLIPTITQALIPYLDKPFAFFGHSMGAIISFEVARLLRKKYRLSPVHLFISGRGA
                     PQVPIEIKPIHNLPKPAFCQELRRLNGTPEEVLENDELMELLLPMLRADFALIENYVYT
                     DERPLDCPISVFGGQQDYKVSGDRLQAWIEQTTADFSMQMFPGDHFFLHSAQQLLLQTL
                     SQKLH"
     aSModule        5381..6058
                     /domains="nrpspksdomains_ctg662_7_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="ctg662_7"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       5384..5410
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg662_7_0001"
                     /evalue="5.30E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="ctg662_7"
                     /protein_end="32"
                     /protein_start="23"
                     /score="9.9"
                     /tool="antismash"
                     /translation="LFCFPYAGGK"
     CDS_motif       5573..5638
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg662_7_0002"
                     /evalue="2.60E-07"
                     /label="NRPS-te1"
                     /locus_tag="ctg662_7"
                     /protein_end="108"
                     /protein_start="86"
                     /score="23.1"
                     /tool="antismash"
                     /translation="KPFAFFGHSMGAIISFEVARLLR"
     CDS_motif       6005..6022
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg662_7_0003"
                     /evalue="3.70E+01"
                     /label="NRPS-beforete1"
                     /locus_tag="ctg662_7"
                     /protein_end="236"
                     /protein_start="230"
                     /score="-1.5"
                     /tool="antismash"
                     /translation="FFLHSAQ"
     CDS             6171..6923
                     /locus_tag="ctg662_8"
                     /transl_table=11
                     /translation="MTKIPKIIHQIFFQGEAAVPEIYARYHQTVLAHHPDWKHYFWDET
                     KSRIFIQKEYPWFLEVYDSYPYQIQRCDTIRYFILHHYGGFYIDMDIECLKPLDDLLED
                     FELILSKLVDFSNAIMGSIPGHPLWLKIFEELPQRKDKYPPNINPLLKKSMPYFVCYST
                     GPILLNDCVVTGKFHESSTVRVCPGYIFEPGAPMEIDGKIIQRNNTEQSYTIHHMTSHW
                     LPLRHRISNAIFRFFVNIYWKILSLQTL"
     CDS             6961..7884
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 192.9; E-value:
                     1.1e-58)"
                     /gene_kind="transport"
                     /locus_tag="ctg662_9"
                     /transl_table=11
                     /translation="MKTLEVYNLQKKYQQGKKSIEALSGLSLTINAGEVLAFLGPNGAG
                     KTTSIKMIAGLIRPDAGWVRIAGCNPHSNPQALRMLGAVLEGSRNLYWRLTPQENLEYF
                     GVLRGIGRTVARKQALKLLDQFGLMHKRSTPVKALSRGMQQKLAIAVALVHKPSLLLLD
                     EPTLGLDVEACQNVKALVRQVASEGCAILLTTHQLDVAEEISDRVAIIQKGKIIAEEST
                     EEIIRRFSGSTYTIKFEGSLDPIQITKIEALGAIIEAEKIIYTGTKPGLYKVLGILEPL
                     PLSHVKQDQSDLTQIFLKLVREYNHD"
     CDS             7877..8650
                     /locus_tag="ctg662_10"
                     /transl_table=11
                     /translation="MIELFQAEIKRIWIEFIRYPVDTISGILANTFVFYGLFLSAKYIG
                     GPNLQVGERLDAIVIGYVLWTLVVFTLEGIAFGLQVEAQTGTLEQVFLSPFGTLRVLMI
                     RGIANLTLNVVLICGVLIFTMLLTKRYLHFPVSIILPLVTVLLGAYGLSLMMAALTLLY
                     KRIQQLLGLVQFALFFLLTFPSEIWNRSLQNLRVILPMTVGSDVLRDLVARNQSLDLSS
                     FLLALMNGMGYFIVGVLVFRWAERQAKRQAILNGY"
     CDS             8913..9182
                     /locus_tag="ctg662_11"
                     /transl_table=11
                     /translation="MAFSGYLPEDTKVHVVPVFIVVVKSPMRFIRASFYSDRVEQISEP
                     RVRYPRNELIYRQPKPHPEDPALVWGFIVFIPALYINYALLPQI"
     CDS             9771..10397
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 89.7; E-value:
                     3.5e-27)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg662_12"
                     /transl_table=11
                     /translation="MKLGAIPENLIERILLASGVVPTPLIDTLIAMLLARTVMVGTKLG
                     VFQALALTALTADEVASHCLTHPETTQKLLNALVGVGYLRVDNNRYLLAPVARKYLLQN
                     RPQSLHENMIFRFLEWAATEHYEDFLRSGKPLDIHKALLSNEQWRLYQRGMGSIAKTLA
                     SEVAQRTLVPQNARDMLDIGGSHGYYSVALCRRHPKLRAVILDLPE"
ORIGIN
        1 ctgtaatccc atacatatta accaagcgtg gcgtttggtc accataacgt tcaaaccagg
       61 gacgtaaact ttctaaattt aatgcttcgc cgccaaaaat cacataccgc aatgctaatt
      121 gagcgatatt tgcttcatct gcacgtataa gctgctggaa tgcagaaggt gtttgattga
      181 ggacagtaac tttttcttgg atcagcagtt cccaaaaagc agctggagaa cgacttaacc
      241 aaaatggaac aacaatcacc ttacccccgt aaagcaatgc tccccacaat tcccaaacag
      301 aaaaatcaaa agcaaaagag tgaaatagtg tccacacatc atttgcgttg aagccaaacc
      361 aaggttctgt agaacgcatc aagcgcatga cgttagcatg agtgacgaca caacccttgg
      421 gagttccagt agagccacta gtgtagataa tataggctgg atgttggggt tgcagcgata
      481 tttgcaaggg caaatctgga taatgagcaa gttcaccctc aatagattcc cagctaaaga
      541 cttctatgtc tgtgtcaagg aattgagaaa tcagaggttc cacaattaac aaggaaacac
      601 cactgtcttc caggataaat tgcaaacgtg aagcaggata attgggatct aggggaacat
      661 aagcaccacc tgcttttaag attcccagta tagcaacaac catgtttcct gagcgttcca
      721 gacataaacc cactcgggtt tctggtttta cgcccaacga ctgtaagtga tgagcaagac
      781 gatttgcctt ttgattaagt tcggtgtacg ttagggtaac attctcaaat tggacagcaa
      841 tatgttgagg atagttgcag acaatctcct caaaagccgt cactaatgtt tctggtgttg
      901 gggatagatt tgcactgatt aagggttttt ggaaaaagcg ctgacgtgct tctgttgaga
      961 gaagagagat atcaaaaatc tgtttgtcta aattttctaa agcatcatta aaaagctttt
     1021 gaaagtgggt caccatttgt tcgatggttt cagcatcaaa ataggcaagg ttatagtcaa
     1081 aatctatttt gatatcactt tgatgatcaa actctcgcac atatattgcc agtggtgttt
     1141 tttgttgtcc actgtagagg ggtacgcaaa ttgtgtgagt gtcctcaaaa gcttcactat
     1201 agtcatgttt ttcgtaggag agggtgatgt caaacagatt ttgatgactt tcggcaattc
     1261 gcttcatctc tcctagaggg aagcgttgat ggcgataatc ttgccttaat aaagaacgga
     1321 ctgtttgtaa aatatcagct aaggtttcgt tactattgat ttctatccga aacgggagca
     1381 tgctgacaaa tagcccgatt gcctctttat aagctttttt actccgattt aaaattggta
     1441 gaccaatgac taaatctttt tggcgatagc gttttgttaa ataaataagt aggatagaaa
     1501 gaataaaatg aaatgcattt gattggattt ctttacaaat gctttctact tgattatatt
     1561 gctgtcgctt aatatagatt gctttccgcc cgccaagtag ttggggtttt gtgatctctg
     1621 gaaaaatctt gggacttaca tcttgcaaac gctgagtcca ataattgcga tcgctttcaa
     1681 aagacttaga ttggagatat gtagtttctt cttctaaata atcgattaaa gttaaatctc
     1741 gttctgcttg ctgaaattca ctcttatgaa gaatttgatt gtaagtgtaa atcacttcct
     1801 taaataaaag ggaagtcccc caaccatcaa cgataatatg atgaaatttt ccataccaga
     1861 gatgtttttg actgctaact cgaatcagct gaaaacaggc tagtgaggaa tcttggccaa
     1921 aatgaaaggg tttttgaaaa tcactctcta tatattcttg agccagttct tcactgttgt
     1981 cataatttga gaaatcaact aaagtcaatc ttgtatcttg gtgttctgct attatctgaa
     2041 aaggtttacc ctcaaattca taaatacgaa ctcgcaagcc aggatgacag cgcagaattt
     2101 ggtttaaggc acaattgaaa acttgagtat ccaaagttcc gacaattgtc ccaattgcac
     2161 caatgttcaa gtgcgaaccc tcagaccacc ttagttggtc aacataaata tcaagctgat
     2221 ttatggataa tgggaatttc gtactcatta ttaattcata tccttgaaat ttatttcagt
     2281 gtgggtgagg taaggctaaa atagccctgc catcagttga cttttctatt tatagggcgt
     2341 ccatatttca cagtcgatac agaaaagtta gggacttgga gcgatcgtac tacttaactt
     2401 ttcagtactc atgccatctc actaaattct tgatacaaat ccatcacctt gtcccccttc
     2461 ccttgtcccc cttgtcctcc ttgtcctcct tgtccccctg actcttagag ttattgagaa
     2521 ttagactgtg gaaaaagcca tgctgttttg tggtttgagt atgatatatt atgattgaaa
     2581 aaaagattat acgaaaactc ctcgtataat tagatagttg cgcggcacgg aacgaataaa
     2641 cgactataaa gactcaatgc agaactccct gaagctcgga ttcttcatcc agcccgtcca
     2701 cccgccgtcc cgttcttata gggacgttct ttgcgaggat cgcgaagcgg tcgtgcttgc
     2761 tgatcggctc ggctaccgcg aggccttcat cggcgagcat ctcgtcgacg cggccgagac
     2821 gatcacctcg agcctcgctt tcattgcgaa tctcgccgat gcgtgcccgt cgatcacctt
     2881 cggtaccggc gtgcttccgc tcgccaacta ccacccggca atggtggcgg cgcaggtcgc
     2941 gatggtggac cacttggtgc agggtcgatt gatcctggga gtcggacccg gtgttgcctg
     3001 tgacgcagaa gccatcggag atttgggctc ggatcgaaat cgcaagaccc aggaggcgct
     3061 cgagcatatg tgccgaatct ggaaggaaga gccgccgtac cggatcgaag gcaagttcta
     3121 ccggaccacc acggagcgct cgctcgatca gaacatcgga gtgggtgtcg ctgtccgacc
     3181 gctacaagag ccccatccgc ccatcgccat cacctcgatc cgaccgagcg ctcagggacc
     3241 gcacgtcgcg ggagcgcgcg gctggtccgg aatctcggcg acctacgtgg gtgcgtacgt
     3301 cgtccgggcc cacattcaga actacgtgga aggccggcga tcggcgggcc tctgtgcaga
     3361 tgcttccggg tggcgcgtgg cgcgcagcat tttcgtggcc gatgacgagg ctacggcaca
     3421 tcgctacgtg catcgtgagg acggcgcgca cgacttctac ttccacgtca tgaggaccaa
     3481 gctcgcgaag gccggcgcgc tggacgtcat gcgcgacttt cccgaccagc cggattccga
     3541 tctctctacg aagcggtgca ttgagcgtct cgtaatcgcg ggaacccctc agagcgttgc
     3601 ggaccagatt cttgcattcc gcaacgaggt cggcgcgttc ggtacactgc tctacacggg
     3661 ccacgactgg accgatccag cgctcgcccg gcgctccatg gagctcatgg cgaacgaggt
     3721 ctggccccgg atcgctcggg ccgcgcatgg gacgacacca aaaggtcaaa ctgacggtaa
     3781 ggcattttca gtctgatgga tagccaaacc aacttccctt ttccacatcc cgtgaaaagt
     3841 cagcttgtcc tcctgttccc tattcccaac ctttacaaat gaatttaatt ttgtccaact
     3901 actcaaagta ttgatatccc taagagtcct aaagcaagct taaaaacctc tagtgcagct
     3961 acactaacgt tagtgtaggc agcactattg ctcaaggact acccccactt aaccagcttg
     4021 cctaaagtat ggggtcacta tcagcttgct tgactaaatc ttgggctact tgttgttggg
     4081 cttgcttgta aaacaagggt ttccaaaatg cttgtgtttc tttcagtcgt agcggatggc
     4141 gattgcctct gtactgcgca gagcacctgc tgttacagaa aagttaagtt tggttcgatt
     4201 ggtaaaatac ttaatttttc tgtatcgacg ctttgaattt tgaatcatat tctaaatcta
     4261 gatggtcgag cggaattagt tattcaatct taaatattta acggagagat actttgactt
     4321 atgagtgtca atttgactgt ggatagaaat attacaaatg taattcaata tcaaataccg
     4381 aatcttactt tacttcccag cagcaaacaa gttacaagga tcaccttaaa tcagttgaaa
     4441 ttagacatag caaaattgga aaaatatctg caagagaaag tagaagaaaa aacaaagcaa
     4501 gagcagaaag ctttaaaaga aaaaatagag aaaggaattc aagaacttga aactatagca
     4561 gaaaaaataa atagtttatc aactgagatt gaagctctaa tgattcagtt taaggaaatt
     4621 gcagttgaag tgaatcgaaa ctatcacctc atacagctac ctcctttttt aaggcaaata
     4681 aaatcggata aatcaaagct aaattgctgg agacctctca atatatggga tgttcattct
     4741 tcttccattc ctactgttgt taggcgtggc gctaaattta tcctaacggt caaaatggtg
     4801 gatctattta acgccgaaag agataagtag gttcataaaa acaacgcaac tatattacga
     4861 aaagtagaca ggatttaata cttaacggaa ggtaaccatg aaaaacaacg aacaacaaaa
     4921 caactctatc tatcttgtgg tggttaatca agaagaacaa tattccattt ggcctaaatg
     4981 gaaaaaagaa atccctttag gttggagaac tgtaggcaaa gaaggttcta aagaggaatg
     5041 tttggcatac atagaagaag tttggacaga tatgcgaccc ctgagtttgc gaaaggcaat
     5101 ggcagaaaag caaacataaa aaatcaactg ctgacattac taaggttatg aaagaatatc
     5161 aaattggctt tgctagagct ttgataatcc tcatctattt ttacgttatg agtctttgta
     5221 tggcagattc agtctatgtc attatcaaat ccattaagac tcagttgtgt gtttctcatt
     5281 gtactccgtc ttcattaatt atcaacaacg aattatgata gctgaactga aacgagaatc
     5341 ctgggtttca tttcccaaac caaatcccca agctagtctg cgcctatttt gctttcccta
     5401 tgcaggtggt aaagcagtga gctttcgcgg ttgggagaag agtttgttga acaccgttga
     5461 agtttgtcct atcgaacttc caggacgggg aacacgattg atggaaaaac catttactca
     5521 tttttcgctg ctgatcccaa ccataactca agctctcata ccctatttgg ataagccatt
     5581 tgctttcttt ggtcatagca tgggggcaat aattagcttt gaagttgcac gtctacttcg
     5641 caaaaaatac cgtttgagtc cagttcatct gtttatttct ggtcgcggcg caccacaagt
     5701 tcccattgaa attaagccta ttcataacct cccaaaacct gcattctgtc aagaactgcg
     5761 tcgcctgaat ggtactcccg aagaagtcct agaaaacgac gaacttatgg aactgctcct
     5821 tcctatgctg agagcagact ttgcactcat tgaaaattat gtatacacgg acgaacgtcc
     5881 ccttgattgt ccgatcagcg tttttggcgg tcagcaagac tataaagtca gtggcgatcg
     5941 cctgcaagct tggatcgaac aaacaactgc agatttctca atgcagatgt ttccaggcga
     6001 ccacttcttc ttacactcag ctcagcaact tctacttcaa accctctccc aaaaactgca
     6061 ccagctgact tataagtacc catgcataac tatttagaac tttttcaaac caactttcct
     6121 gttccctctt aaaatttgtc cctaaagtcc taattaacca aatcaaagtt atgactaaaa
     6181 ttcccaagat tatccatcaa atattttttc agggtgaagc tgcagttcca gaaatttatg
     6241 ctcgttatca tcaaaccgtt ttggcacatc atcctgactg gaaacattat ttttgggatg
     6301 aaacaaaatc ccggatattt atccagaaag aatatccctg gtttttagag gtatatgatt
     6361 cctatcctta tcagattcag cgttgcgaca ccatacgcta tttcatcctt catcactatg
     6421 gtggattcta cattgacatg gatattgaat gtcttaaacc tcttgacgat ttactcgaag
     6481 actttgagtt aattctttca aaacttgttg actttagtaa cgctattatg ggtagtattc
     6541 ctggacatcc gctctggtta aagatattcg aggaattgcc acaacgcaaa gataaatatc
     6601 ctccaaatat taatccctta ctcaagaagt caatgcccta ctttgtatgt tacagcacag
     6661 gaccaatttt attaaatgat tgtgtagtaa caggcaagtt tcatgaaagt tctactgtcc
     6721 gcgtctgtcc aggatatatt tttgaaccgg gcgctcctat ggaaattgat gggaaaatta
     6781 ttcagcgaaa taacacagaa cagtcttaca ccatacacca tatgaccagt cattggcttc
     6841 ctctgcgtca tcggatatcc aatgctattt ttcgtttttt cgtaaacatc tactggaaaa
     6901 ttctctcttt acaaacactt tagatattag tttttatcat tactcgaaat tagaaaagcc
     6961 atgaaaacac tagaggtgta caaccttcaa aagaaatacc aacaaggtaa aaaatccata
     7021 gaagcgttat ctggtttatc attaactatc aatgctggag aagtgttggc ttttctaggt
     7081 ccaaatggag ctggaaagac aaccagtatc aagatgattg caggcttaat tcgaccagac
     7141 gctggatggg tgagaatagc aggttgcaat cctcactcca atccacaggc gctgcgcatg
     7201 ctgggtgcgg tactagaagg aagtcgtaac ctctactggc ggttaactcc acaggaaaat
     7261 ctagagtatt ttggggtatt gagaggaatt ggtcgcacag ttgcgcgcaa gcaagcacta
     7321 aagctgttag accaatttgg tttgatgcat aaacgtagta cgcctgtaaa ggcactttcg
     7381 cgaggaatgc agcagaagtt agctattgca gtagctttag ttcataaacc cagccttctg
     7441 ctattagatg aacccacttt aggtttagat gtggaggcgt gccaaaacgt taaagccttg
     7501 gtgcgacaag tagcatctga aggctgtgct atcttactca ccacccatca attggatgtt
     7561 gcagaagaaa tatcagaccg ggtggcaatt attcaaaaag ggaagataat tgcagaggaa
     7621 tcaacagagg aaattatccg gcgtttttct gggtccacct atactatcaa atttgaaggt
     7681 tctctagacc caatacaaat caccaaaatt gaggctttag gtgcaatcat cgaagcagaa
     7741 aaaattattt atactggtac aaaacccgga ctatataagg ttttaggaat tttagaacca
     7801 ttacctttat cacacgtaaa acaagatcaa tcagatctca ctcaaatatt tttaaaatta
     7861 gtaagagaat acaatcatga ttgaactatt ccaggctgaa atcaaacgta tttggataga
     7921 gtttatccgc taccctgttg atactattag cggcatcctt gctaacacat tcgtttttta
     7981 tggactgttt ttaagtgcta agtacattgg tggtcccaac ttacaagtgg gtgaacggct
     8041 agatgctatt gtgattggct atgtgctttg gacgctggtt gtatttactc ttgaaggtat
     8101 tgcctttgga ctccaagtag aagcccaaac tggaacttta gaacaggtat ttctatcacc
     8161 attcggtacc ttaagggttt tgatgattcg cgggattgca aatctcacct taaatgtagt
     8221 gttaatttgt ggtgtcttaa tatttaccat gctgctgacg aaacgttact tacactttcc
     8281 agtaagtatc atcctaccgc tcgttacagt gttactggga gcttatggtc tgtccttgat
     8341 gatggcagct ttaaccttac tttataaacg tatccaacaa ctgttggggc tggttcagtt
     8401 tgcactcttt ttcttgctga cctttccctc tgaaatctgg aatagatctc tacagaattt
     8461 gagagtcata ctaccaatga ctgtgggttc agatgtcctt cgggatttag tggcacgtaa
     8521 tcaaagtcta gacttatcta gtttcttgct tgccttaatg aatggaatgg gatatttcat
     8581 tgtgggtgtg ttagtgtttc gttgggctga acgccaggcc aagcgtcaag caatactcaa
     8641 cgggtactga aattcctagg tatcaaaagt tttaaacgta aagattgacc tcccagctac
     8701 cccaaagaga acgtggggtg gctgttttat ttctccccat ttgtctagct tttgtctatc
     8761 aaagttaagc tagcactgta gaatgatagt aatctcatta actgtattgt cacgtccttc
     8821 ggtgggggtg acattttatt gcggttctac aattaggcct caagctagag aaactatcac
     8881 ctggtgccaa gtagctaaaa gtattcctaa tcatggcttt cagcggttat cttcctgaag
     8941 atacaaaagt tcacgtagtt cctgttttca ttgtggttgt aaaatcacct atgcgattta
     9001 tccgcgcctc attctacagt gatagagttg aacaaatctc tgagccaaga gtacgttatc
     9061 ctaggaatga attaatatat cgacaaccca aaccccaccc cgaagacccc gcactagtgt
     9121 ggggcttcat cgtctttatc cccgccttat atataaatta cgctctcctg ccacaaattt
     9181 agagcatact acaaagctac atattcctct tacgtactac ataaatttag ggcacgggta
     9241 cgaggcaacg aaccgcgatc gcactgggtt agcacttagc actaaaatat acatcgcatc
     9301 ctattgctag gagcatatgt caagctgttt tttattttat actatgcttt gatctctatt
     9361 atagaactac tttctaataa gtaaatgaca ccaaattact gaaaaatata ggtatttttt
     9421 gcgtaaatct gctatagata ataccccaaa aactaattat tataattatt gaatatttag
     9481 ctataaacta aattatgaat tgagtattta gcaaaaaaag tctaatctga aaaaataaaa
     9541 tatgagaaga aaccattata aataaatttc atttacccaa tcgatcatat ttttttcact
     9601 tttgaaagca cagtcacaca atactgatag aagctccctc gcaggtgcag tagtattaaa
     9661 cctcttactt tttttgattt ctctactcat acttgtaaaa ttcccgtaga aatcaagggc
     9721 tttaacccca atgattattt taagtacaaa gatgttagag gagataaacc atgaaacttg
     9781 gtgccattcc tgagaatctc attgagcgaa ttttacttgc gtcgggagtg gtgccaacac
     9841 ccctcattga cactttgata gccatgttgc tagcgcgaac tgttatggtg ggaacaaagc
     9901 ttggcgtatt ccaagcactt gcactaacag cgcttactgc agacgaagtt gcatcacact
     9961 gtctgactca cccagagact acacaaaaat tgctgaacgc acttgtaggc gtaggctatc
    10021 tgcgtgttga taacaaccgt tacttgcttg cgccagttgc ccgaaaatat cttctgcaaa
    10081 atcgcccaca atcactccat gagaacatga tcttccgatt tttggaatgg gctgccactg
    10141 aacattacga agactttctc cgcagtggga aacctcttga cattcataaa gcactattaa
    10201 gcaatgaaca atggaggctg tatcaacgag ggatgggctc aatagcaaaa acattggctt
    10261 cggaagtagc acaacgcacg ctggttccac agaatgcacg tgatatgctt gacatcggcg
    10321 gttcgcatgg gtactactca gttgcactct gtcgccgtca tccgaagctt cgtgcggtca
    10381 tcctcgatct ccctgaa
//
