LOCUS       c00706_3300027..        9828 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027965.a:Ga0209062_1007119.
ACCESSION   c00706_3300027..
VERSION     c00706_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 03:16:34
            Original ID  :: 3300027965.a:Ga0209062_1007119
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9828
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9828
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2825](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..2825)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..9828
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9828
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..2825)
                     /NRPS_PKS="Domain: AMP-binding (17-418). E-value: 1.2e-83.
                     Score: 272.7. Matches aSDomain:
                     nrpspksdomains_ctg706_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (527-596). E-value: 9.7e-25. Score:
                     78.3. Matches aSDomain: nrpspksdomains_ctg706_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (615-916). E-value:
                     6e-125. Score: 407.9. Matches aSDomain:
                     nrpspksdomains_ctg706_1_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     342.9; E-value: 4.3e-104)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg706_1"
                     /sec_met_domain="Condensation (E-value: 4e-86, bitscore:
                     278.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8e-92, bitscore:
                     297.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-15, bitscore:
                     46.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLTSRTLQNLTINQLLTEQAEQNPYGIAITAPNRLPLSYRRLYT
                     HIHDTAKTLNAMGLGRDDRIALVLPNGPEMAVAFLAVANCATCAPLNPAYLTSEFDFYL
                     GDLNAKALIVQSEIDSPARAVAMARNIKIIELVSIQQAEAGIFQLVGDTKLPPIDKGFA
                     QSEDVALVLHTSGTTSRPKIIPLSQVNLSVSVHNIKTALELCQSDRYLNVMPLFHVQGL
                     ISTIASIAAGASVICTPGFDASKFFAWLQAMQPTWYTAVPTVHQAVLAASVDHCDEFDH
                     FTPLRFIRSAGAALPPKVLAALEELFSTVVIETYGMTETGSVISSNCLPPRLRKPGSVG
                     IAAGLEVGIMNEMGHLLASGEIGEIVVRGDNVISEYENNPAANQNAFRNGWFRTGDQGY
                     LDSDGYLFITGRLKEIINRGGKKISPREIDEVLLEHPKVAQAVSFAVPHPTLNEDVAAV
                     VVLRQNVTINEREIREFAAAKLADFKIPSQVVFVDEIPKSSTGKIQRINLAQKLVTELT
                     APFVAPTTKVEKVLAEIWTEVLGVQQVGVYDNFFTLGGDSLSATQVISRLFAVLQVDIP
                     LSKFFKAPTIMGLSEMLTQNQVVLQLGLQAISILPRTQNEDIPLSFAQQRLWFLDQFVP
                     NTPTYNIPLAYRVTGQLNVKALEQSLCEIVRRHEVLRTTFRDVDGQPIQLISPEIDLRL
                     RVVDLRETYKTELDAQVQRLATEEAKQPFDLTQGLLLRTKLLRLDEAEHVLLLVMHHIV
                     SDGWSMGVLVRELAIVYQAVCNDLPIALPELPIQYADFAIWQREWFSGEALESNIAYWK
                     KQLGGELPILELPTDRPRPPVQTYQGSRQSFELSKELTDALNVLSQQEKVTLFMTLLAA
                     FKMLLYCYTGQEDVIVGSPIANRNRAEVEGLIGFFVNTLVLRSDLGGSPSFRELLSRVR
                     KVALEAYDHQD"
     aSDomain        complement(78..980)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg706_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="6.00E-125"
                     /label="ctg706_1_Condensation_LCL.1"
                     /locus_tag="ctg706_1"
                     /protein_end="916"
                     /protein_start="615"
                     /score="407.9"
                     /tool="antismash"
                     /translation="EDIPLSFAQQRLWFLDQFVPNTPTYNIPLAYRVTGQLNVKALEQS
                     LCEIVRRHEVLRTTFRDVDGQPIQLISPEIDLRLRVVDLRETYKTELDAQVQRLATEEA
                     KQPFDLTQGLLLRTKLLRLDEAEHVLLLVMHHIVSDGWSMGVLVRELAIVYQAVCNDLP
                     IALPELPIQYADFAIWQREWFSGEALESNIAYWKKQLGGELPILELPTDRPRPPVQTYQ
                     GSRQSFELSKELTDALNVLSQQEKVTLFMTLLAAFKMLLYCYTGQEDVIVGSPIANRNR
                     AEVEGLIGFFVNTLVLRSDLG"
     aSModule        78..980
                     /domains="nrpspksdomains_ctg706_1_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg706_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(87..176)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg706_1_0007"
                     /evalue="3.00E-18"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg706_1"
                     /protein_end="913"
                     /protein_start="883"
                     /score="58.1"
                     /tool="antismash"
                     /translation="DVIVGSPIANRNRAEVEGLIGFFVNTLVLRS"
     CDS_motif       complement(429..467)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg706_1_0006"
                     /evalue="1.50E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg706_1"
                     /protein_end="799"
                     /protein_start="786"
                     /score="20.6"
                     /tool="antismash"
                     /translation="QYADFAIWQREWFS"
     CDS_motif       complement(516..581)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg706_1_0005"
                     /evalue="2.50E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg706_1"
                     /protein_end="770"
                     /protein_start="748"
                     /score="39.1"
                     /tool="antismash"
                     /translation="MHHIVSDGWSMGVLVRELAIVYQ"
     CDS_motif       complement(798..914)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg706_1_0004"
                     /evalue="4.10E-20"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg706_1"
                     /protein_end="676"
                     /protein_start="637"
                     /score="64.2"
                     /tool="antismash"
                     /translation="PTYNIPLAYRVTGQLNVKALEQSLCEIVRRHEVLRTTFRD"
     CDS_motif       complement(933..965)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg706_1_0003"
                     /evalue="1.50E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg706_1"
                     /protein_end="631"
                     /protein_start="620"
                     /score="11.0"
                     /tool="antismash"
                     /translation="SFAQQRLWFLDQ"
     aSDomain        complement(1038..1244)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg706_1_PCP.1"
                     /evalue="9.70E-25"
                     /label="ctg706_1_PCP.1"
                     /locus_tag="ctg706_1"
                     /protein_end="596"
                     /protein_start="527"
                     /score="78.3"
                     /tool="antismash"
                     /translation="EKVLAEIWTEVLGVQQVGVYDNFFTLGGDSLSATQVISRLFAVLQ
                     VDIPLSKFFKAPTIMGLSEMLTQNQ"
     aSModule        1038..2774
                     /complete
                     /domains="nrpspksdomains_ctg706_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg706_1_PCP.1"
                     /locus_tags="ctg706_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(1572..2774)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg706_1_AMP-binding.1"
                     /evalue="1.20E-83"
                     /label="ctg706_1_AMP-binding.1"
                     /locus_tag="ctg706_1"
                     /protein_end="418"
                     /protein_start="17"
                     /score="272.7"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="TEQAEQNPYGIAITAPNRLPLSYRRLYTHIHDTAKTLNAMGLGRD
                     DRIALVLPNGPEMAVAFLAVANCATCAPLNPAYLTSEFDFYLGDLNAKALIVQSEIDSP
                     ARAVAMARNIKIIELVSIQQAEAGIFQLVGDTKLPPIDKGFAQSEDVALVLHTSGTTSR
                     PKIIPLSQVNLSVSVHNIKTALELCQSDRYLNVMPLFHVQGLISTIASIAAGASVICTP
                     GFDASKFFAWLQAMQPTWYTAVPTVHQAVLAASVDHCDEFDHFTPLRFIRSAGAALPPK
                     VLAALEELFSTVVIETYGMTETGSVISSNCLPPRLRKPGSVGIAAGLEVGIMNEMGHLL
                     ASGEIGEIVVRGDNVISEYENNPAANQNAFRNGWFRTGDQGYLDSDGYLFITGRLKEII
                     NRG"
     CDS_motif       complement(1665..1748)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg706_1_0002"
                     /evalue="3.80E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg706_1"
                     /protein_end="387"
                     /protein_start="359"
                     /score="12.9"
                     /tool="antismash"
                     /translation="GEIGEIVVRGDNVISEYENNPAANQNAFR"
     CDS_motif       complement(2265..2321)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg706_1_0001"
                     /evalue="9.60E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg706_1"
                     /protein_end="187"
                     /protein_start="168"
                     /score="12.2"
                     /tool="antismash"
                     /translation="ALVLHTSGTTSRPKIIPLSQ"
     CDS             complement(3061..3462)
                     /locus_tag="ctg706_2"
                     /transl_table=11
                     /translation="MRNSENIFHLAIPCKEVNEAQHFYVEKLGCKLARRYADRVTLNFF
                     GNQLVCHLSPNEIEISPKMYPRHFGITFKRKEEFDALLTRAKEQGIDFFQKPTVRFAGK
                     LEEHLTFFLKDPSNNLLEFKFYKDSQMMY"
     CDS             complement(3469..4359)
                     /locus_tag="ctg706_3"
                     /transl_table=11
                     /translation="MYLQITSILGRLIIQIAQPYRDTTYRHLLFMKNKNTLDFSEKKTF
                     LKLPRREVKPRVNGLTILIDNGISTDYFYDVLKSYGEFIDLIKFGWCTSIISKNIANKI
                     AYASAQGIDFYFGGTLFEKAVQQNQVDSLYTYFKHYSCKYIEISNGTIDLANKEKAKYI
                     SDFSREFKVLSEVGYKEPQKSLKLSSEEWIEYMLEDLDAGAVKVITESRESGMSGICSA
                     NGEIRCEITQKIFNSGIKIEDIIFEAPNKQLQVYFVKELGTNVNLANIAFSDIIGLETL
                     RLCLRYETFNLFEEM"
     CDS             4468..4740
                     /locus_tag="ctg706_4"
                     /transl_table=11
                     /translation="MYPREKSGKSKGILIHTSTDGNGLPLANRTTLANGSERDQVIPLL
                     DSVKVKMNRSGKSRKRVKILAADKGNADLMSQWQQHDVHNAAFRK"
     CDS             complement(5376..5822)
                     /locus_tag="ctg706_5"
                     /transl_table=11
                     /translation="MPTSSVPLKLESLADYVKRIRLNLQMSQLELAAACGIHPHTYSKI
                     ERGKTTRLNRKTLQGLAVALSIPQEYLEAICKGEEVKFVAAVKFCPQCWTPGTAADPIW
                     TDVRSRHCFICGTPLRSHCVNCGELVASLKYRFCPFCGFAYKNS"
     CDS             5906..6811
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 144.8; E-value: 7.9e-44)"
                     /gene_kind="other"
                     /locus_tag="ctg706_6"
                     /transl_table=11
                     /translation="VSVTLATVTTEFLERPGLAKSTRRTYELVLLPLLQEYGWWSVEIL
                     SRQILIEYLHSLSHLKYTTHHKHQAILQSLMSFAVEQGYIKSNPIRGLKQRQPDKEKGE
                     HHTEEVIRFLIPEQLNVLYKAVASNLRMSAIVHLLHRTGCRISELLALDISNVDLDKQK
                     FQVIGKGNKQRWCFYSLDAANALNKYLKQERYNNCPALFTAQQPVTKVVNRISYRTVHD
                     NWRELIEPYPQLQGVRIHDLRHTFATERVGLMGIVELGALMGHGSIQTTLRYQKVTSAR
                     AEEIARKALSHLINTNVDRN"
     CDS             complement(6844..7377)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 135.6;
                     E-value: 2.8e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg706_7"
                     /transl_table=11
                     /translation="MTTIETPRLLLRPIAQTDLDDLAQIYRAPEVMRYRLFSQPASFKQ
                     TQKFLASYLSHWEQHGFGRWATIYKASQQLIGHCGLEYIATLDEVEVNYLLSSKYWGQG
                     LATESAIAIVSYGFKILQFERLIALAKPENLASVRVMEKIGMQFHKNIQLYEMEWAFYT
                     IKRDQWQYSNSFMS"
     CDS             7549..7893
                     /locus_tag="ctg706_8"
                     /transl_table=11
                     /translation="MTVIERTAYPRFKQYPSPKELAEFYTPTPEEIKFVKPRVKSHEGL
                     LSFMVMLKSFQRLGYFPHPEQVPIAVIKHLRTCLKLREWIKAIPSERQRRNYEQAIRSH
                     LKVKPYRGSF"
     CDS             7978..9807
                     /locus_tag="ctg706_9"
                     /transl_table=11
                     /translation="VRYDKVAQKLVAIVVATSAQVKDHPADLINIAIEELIKERYELPA
                     FSTLDRLVSHVRSVTNYRLFLRVSRLLSTEEKAFLDQLLLGETSESNATLNLLKSPPKS
                     AKLSHMQQLQKKFNQLMTFGDAKRLLSSLAPAKVKYLAAQAAALDISEFQDIKLSKRRT
                     LLLCLLYQAQVKTRDHLVEMFLKRIQKIINNAKTRLRELREKHLEQTEELLGILAQILA
                     VSNETEDKTTLGHQVQTLFAEHGGSELLLKQYEEIAAYNSNNHLPLMWHFYSRYRKLLF
                     ELVSSLDIHSTSADDSLINALAFVLKNEHRRTKYLSADIDLSFISNQWRSLVFTRIENT
                     EMLVRQQLEICVFSYLATELKTGDACVVGSESYADFRDQLLSASECTPMIEQYCNELGF
                     PSNPEDFVEHLRNSLVLVAESVDQICSDGKQVTISKDGEPILKRIAPSPAPEGVEELEE
                     AIRQKIPERSILDILCNVEHWLNWTRHFGPLSGNEPKMQHASERYILTAFGYGCNLGPN
                     QTARHTRGVVTSHMISYTNRRHISVQNLEAAVRDMINAYNRFHLPTMWGTGKRAAADGS
                     KFEVYENNLQSEYHIRYGGYGGIAYHLVSDLTG"
ORIGIN
        1 atatcctgat gatcataagc ctccaaagct accttacgca ctcgacttaa caattcccga
       61 aaactgggag acccacccag atcagaccgc agtactaaag tattgacaaa aaagccaatt
      121 agtccctcaa cttcagcccg gttgcgatta gcaatgggag aaccaacaat aacgtcttcc
      181 tgccccgtat agcagtaaag taacatcttg aacgcggcca acagagtcat aaacaaagta
      241 accttttcct gctggctcag cacgttaaga gcatccgtta actccttcga tagctcaaac
      301 gactgccttg acccctgata tgtttgcact ggaggacgtg gacgatcagt cggtaattcc
      361 agtataggta actcccctcc tagctgcttc ttccagtaag caatgttcga ctccagcgcc
      421 tctccagaga accactccct ctgccaaatg gcaaaatcag catattgaat cggcaactct
      481 ggtaacgcaa ttggtaaatc gttgcataca gcttggtaga ctattgctaa ctcacgcacc
      541 aaaacgccca ttgaccatcc atctgaaact atgtggtgca tcactagtag taggacatgt
      601 tctgcttcat ccaaacgcag aagcttagtg cgcagtaaca gtccttgagt taaatcaaaa
      661 ggctgtttag cttcctctgt agccaacctc tggacctgag catctagctc tgtcttatat
      721 gtttcccgga ggtctactac tcgtaacctt aagtctatct ctggagagat cagctgaatt
      781 ggttgcccgt ccacatctct aaaagttgtg cgcaaaactt catggcggcg tacaatttca
      841 cataggctct gctccaatgc ctttacattt aactgacccg tgacccgata agcaaggggg
      901 atgttatatg ttggtgtatt aggcacaaac tgatcgagaa accaaagtcg ctgctgagca
      961 aaagataatg gtatatcttc attttgcgtt ctaggtagaa ttgatattgc ttgcagacca
     1021 agctgcaaca caacctgatt ttgtgtcagc atctcggaca aacccatgat ggtaggtgct
     1081 ttaaagaatt tcgataaggg aatatctacc tgtaaaactg cgaaaagacg cgaaataact
     1141 tgggttgcgc tgagagagtc gccgcccaag gtgaagaaat tgtcgtaaac tcctacctgc
     1201 tgaacaccaa gaacttcagt ccaaatttct gctagcactt tttctacctt agttgtaggt
     1261 gcgacgaaag gtgccgtcag ttctgtcacc agtttctggg ctaaattaat acgctgtatt
     1321 ttccctgtgg aacttttggg aatttcgtca acaaacacta cctgagatgg tattttgaaa
     1381 tcagccagtt tagctgcggc aaattcacga atttctcttt cattgatagt aacgttctgc
     1441 cgcaacacaa cgactgctgc cacatcttcg ttgagagtag gatggggaac tgcaaagcta
     1501 actgcctgtg ccacctttgg gtgctccagt agtacttcgt caatttcacg aggggaaatt
     1561 tttttccctc ctcggttgat gatttctttc agacgacctg tgatgaaaag atagccatca
     1621 ctatctaaat atccttggtc acctgtccta aaccagccgt ttctgaaggc attttgatta
     1681 gctgctggat tgttttcgta ctcagagatc acgttatcac cccgaactac aatctctcca
     1741 atttcaccag atgccagtaa gtgtcccatt tcattcataa tgccaacttc tagccctgcg
     1801 gctattccta ctgaacctgg tttgcgtagg cgtggcggta aacagttact tgatattacg
     1861 ctaccagtct cagtcatccc gtaagtttct atcaccacag tactaaacaa ctcctctaaa
     1921 gctgccaata ccttgggtgg taaagcagca ccagcagaac gaataaatcg cagtggtgta
     1981 aagtgatcaa attcatcgca atgatctaca gatgctgcta aaactgcttg atggacagtg
     2041 ggtactgctg tgtaccaagt tggttgcatt gcttggagcc aagcaaaaaa cttagaggca
     2101 tcaaatccag gagtgcaaat aacactggct cctgctgcta tagaggcaat tgttgaaatt
     2161 aagccctgta catgaaacag cggcatgacg ttcaggtagc gatcactctg acacaattct
     2221 agtgccgttt taatgttatg aactgagaca ctcaaattaa cctggctcag aggtattatt
     2281 ttaggacggg aagtagttcc tgacgtatgc agaactaggg caacatcctc agattgtgca
     2341 aaccccttgt caataggagg taacttagta tctcccacaa gctgaaaaat tcctgcctct
     2401 gcttgttgta ttgataccaa ctcaataatc ttaatattac gagccattgc cactgctcta
     2461 gcaggggaat ctatttccga ttgcacaatc agggctttcg cattcaaatc gccgaggtaa
     2521 aagtcaaact cagaagtaag ataagctgga tttaggggtg cacatgtggc acagttggct
     2581 accgctagga atgccaccgc catctccgga ccattgggta gcactaatgc aatacgatca
     2641 tctcgaccaa gccccattgc atttaaggtt tttgccgtat catggatgtg ggtgtatagg
     2701 cgccggtagc tcaggggcag gcgattagga gcagtaatcg ctattccata aggattttgt
     2761 tcagcttgtt ctgtaagcaa ctgattaata gtcaaattct gtaaagttct gctagttaga
     2821 tgcatctgag tttttccact atataaacaa caattgctaa ttctataaat aagtagctgt
     2881 cataaaatac gtgcgttagg atgtgcaaaa aatgaataaa agaaacacta tttccttgaa
     2941 cgctttctct acaaaaattt cagtaagtgt ttcttgatag aaggctattt atataaaaaa
     3001 cacttttaca atcccgccaa atcttgcaac atcacccttt ttctgacaat acgattatac
     3061 ttagtacatc atttgtgaat ctttataaaa tttaaattct aataaattat tagatggatc
     3121 ttttaaaaaa aaagtcaaat gttcctctaa ttttcctgca aacctcaccg taggcttctg
     3181 aaaaaaatca ataccttgct cttttgctct tgttaataag gcatcaaatt cctcttttcg
     3241 tttaaaggtt ataccaaaat gcctaggata catttttggt gatatctcta tttcattagg
     3301 agaaaggtga caaactaact gatttccaaa aaaatttaga gtaactctat ctgcatatct
     3361 gcgagctagt ttacacccta gcttttcaac atagaaatgc tgagcttcat tgacttcttt
     3421 acaaggtata gctaagtgaa aaatattttc tgaatttctc attattcctc acatttcctc
     3481 aaataagtta aatgtttcat aacgtagaca aagcctcaaa gtttcaaggc caataatatc
     3541 agaaaatgca atatttgcta aattaacatt tgtacctaac tctttgacaa agtaaacctg
     3601 tagttgcttg ttaggagctt caaaaattat atcttcaatc ttgattcctg aattgaaaat
     3661 tttttgtgtt atttcgcatc tgatctcccc attggctgaa caaattccac tcattccact
     3721 ctcgcgagat tctgtaatga cttttactgc tcctgcatcc agatcttcta acatatattc
     3781 gatccactct tctgaagaca attttagtga tttttgtggt tctttgtacc caacctcgct
     3841 caaaacctta aattctctag aaaaatctga aatatacttt gctttttctt tatttgctaa
     3901 atcaattgtt ccatttgata tttctatata tttacagctg taatgcttaa aataagtata
     3961 gagagaatcc acctggtttt gctgcaccgc tttttcaaag agagttcctc caaagtaaaa
     4021 atctatccct tgggctgaag catatgctat tttattcgca atattttttg aaattataga
     4081 agtgcaccag ccaaatttta ttaaatcaat aaattcaccg taactcttaa gaacatcata
     4141 aaagtaatct gtagaaattc cattatctat taaaattgtt aatccattta cacgtggttt
     4201 aacttctctc ctaggtaact taagaaatgt ttttttttcg ctaaagtcta gtgtattttt
     4261 gtttttcata aacaataagt gacggtaagt tgtatcacgg tatggctggg caatttgaat
     4321 gattaagcga cctagaatgg aagttatttg aagatacatt tcccaaggaa gcagaaaacg
     4381 gaggggagga atgcctcatg cgctgtttcg ttatgtagtt aataccttac tgtacatata
     4441 tattgataac cggatgtcgt tcgtgtaatg tacccaaggg agaaatctgg gaaaagtaag
     4501 ggaattttaa tacatacctc gacagatggt aatggtctgc ctttggctaa tcgcacaacc
     4561 ttagctaacg gtagtgaaag agatcaagtt ataccattgt tagatagtgt caaggttaaa
     4621 atgaatagat ccggtaaatc tcgcaaacga gtcaaaatat tagctgctga caaaggcaac
     4681 gctgatttaa tgagccaatg gcaacaacat gatgttcata atgcagcatt tcgtaaatag
     4741 aaatctcaat cccgtagcta ggctcataca tagcttttca aaatctttta attggcaatt
     4801 ggcagttaat tttaaatttt ttaagcctta aaatgcgtta acttgaccaa tgaactgtat
     4861 ctcctaaaaa agatagttgc atatatggct ataaaaaaca aggggcgttg ctgaatcaaa
     4921 ttatgaatgt gcaatctacg gttgtgtaga gacgtagcaa tgctacgtct ctacaaggat
     4981 ttgggttttg gctacaaaaa tactacaaag acaattcata cctaaattca gcaacgccaa
     5041 acaaggggtg atattctcaa gctcgcttct ttagatgaac tatggtaggt tcatgtctaa
     5101 taatacagta aatcaactga tttatcgtag tttaatacaa aatgttacta acccagttga
     5161 aagagttgct gtgccagata ggcattgagc cgagatcctt gtaaaatcat gcaagatggt
     5221 ctagaaagcc ttactatgtc tgagatacag acattttcat aaaatttagg ttacataagt
     5281 ttttgtgcaa atacggttga caaagaaacg aatcttcaga aatctcttgg tcatcaagaa
     5341 tagcaaaagt aggaaagctt gctatatctt gcgttttagc tatttttata ggcaaaacca
     5401 caaaaaggac agaaacggta tttgagcgaa gcaaccaatt caccacagtt gacacagtgg
     5461 gaacgcagag gagtaccaca gataaaacaa tgtctagagc gtacgtctgt ccatatagga
     5521 tctgccgcag ttccaggagt ccaacattga ggacaaaact tgacggcggc gacaaattta
     5581 acttcctctc ccttgcaaat agcctccaaa tattcttgag gaatagataa ggctactgcc
     5641 agaccctgaa gagttttgcg attcaatctg gtagttttac cccgttcaat cttgctgtat
     5701 gtgtggggat gaatgccaca agcagctgcc aactccaatt gactcatctg taaattcaga
     5761 cgaatgcgct tgacgtagtc cgctaaggat tcaagcttta aaggaactga agaagttggc
     5821 atgaaaagtt gtcataatct tgtgaaaaag gatatatgat ttaagaaata tttaccttga
     5881 taaaattaca gaaattggca ttcaagtgtc tgtcacttta gccactgtta ctactgaatt
     5941 tctagaacgt cctgggctag caaagagtac taggcgtaca tatgaattgg ttctattacc
     6001 tttgctacag gagtatggat ggtggtcagt tgaaattctg agccgtcaga tattgattga
     6061 atatctacat agtttgagcc atttaaaata cactactcat cacaaacatc aagcaatatt
     6121 acaaagcttg atgagttttg cggtagaaca aggttatata aaatccaatc caatcagggg
     6181 attaaaacaa cgtcaaccag acaaagaaaa gggagaacac catacagagg aagtcatacg
     6241 ctttctgatt ccagaacaat taaatgtact gtacaaagct gtagccagta acttacggat
     6301 gagtgcaatt gtacatttat tgcatcggac aggatgccga atttctgagc ttttggcatt
     6361 agatatctcc aatgtggatt tagataagca gaagtttcaa gtaattggta aagggaacaa
     6421 acagcgttgg tgtttttaca gtttagatgc tgctaatgca ctcaataaat atcttaaaca
     6481 agagcgatac aataactgtc ctgctttatt tacagcacaa caaccagtta caaaagtggt
     6541 taataggatt agctatcgta ctgtgcatga caattggaga gaattgattg agccatatcc
     6601 tcaactgcaa ggtgtacgca tccacgattt acgtcatacc tttgctacag aacgagttgg
     6661 tttgatggga attgtggagc taggagcatt gatggggcat ggaagtattc aaacaacact
     6721 tcgttatcaa aaagttacat cagcaagggc agaagaaatt gcacgtaaag cactttccca
     6781 cttaattaat acaaatgtag acaggaattg agaaagcaca caaaagtaat aaaatgtcct
     6841 accttatgac atgaagctgt tagaatactg ccactggtca cgctttatag tgtaaaacgc
     6901 ccattccatc tcatagagtt gaatgttttt gtgaaattgc atccctattt tctccatcac
     6961 acgaactgat gcaagatttt ctggttttgc tagcgctatc aatcgttcaa attgcaagat
     7021 tttaaaacca tagctgacta tagcaattgc cgactctgtt gctaatccct gcccccagta
     7081 cttactcgat aacaagtaat tcacttcaac ttcgtcaaga gttgctatgt actccaatcc
     7141 gcaatgtcca atcaactgct gtgacgcttt gtaaatcgtt gcccatcgac caaacccgtg
     7201 ttgctcccag tgtgacagat aggatgccaa aaacttctga gtttgtttga atgaagctgg
     7261 ttgcgaaaat aagcgatatc tcatcacctc aggagctcta tatatttggg ctaaatcatc
     7321 caaatctgtc tgtgcaattg gacgcaatag cagacgcgga gtttctatcg tagtcataca
     7381 ttgaacgttt tgtgcatcct tacttattaa agtataggca ccagtatttt tagtctttta
     7441 aaagatctat ggtgaaaaga agataaaata ctctgcacca ggcaactgag ggatgtccaa
     7501 gatacgggta caactctcta aggcttttac gttgtaaata ttacttgaat gaccgtaatt
     7561 gaacgtacag cttatcctcg ctttaaacaa tatccgtcgc ctaaggagtt ggctgaattt
     7621 tatacaccaa caccagaaga aatcaagttc gttaaacccc gtgtcaaaag ccatgaaggg
     7681 ttgctgagtt ttatggtcat gctgaaatca tttcaacggc ttggttattt tccgcatcca
     7741 gaacaggtac ctattgctgt catcaaacat ttacgaacgt gtttaaagct acgtgagtgg
     7801 attaaggcaa ttccctctga gcgtcaacga cgtaattatg agcaggcaat acgttcccac
     7861 ctgaaggtaa agccttaccg agggtctttc tagagaggag ggcaacctta aaagccccac
     7921 gattcatctt gaggacagac gactatctcc tgaaggttgc cctcctctcc agacaaagtg
     7981 cgttacgaca aagttgccca aaagctcgta gctatagttg ttgctacatc cgcacaagtc
     8041 aaagaccatc ctgctgactt aatcaatatt gctattgaag aattaatcaa ggaacgatat
     8101 gagttacctg ccttcagcac cctggatcga ctggtgagtc atgtgcgttc cgttactaat
     8161 tatcgacttt ttttacgtgt ttcgcgctta ttatcaacag aggaaaaagc ttttttagac
     8221 caactgttgt taggagaaac ttctgaatca aatgcgactc ttaatttact gaagtctcca
     8281 cctaaaagtg ctaaactgtc gcatatgcag cagttgcaga aaaagtttaa tcagttgatg
     8341 acttttggtg atgcaaaacg attactatca tcacttgctc ctgccaaagt caaatattta
     8401 gcggcacaag cggcagcttt agatatatca gaatttcaag atatcaaact ttcaaaacgt
     8461 cgtaccttgt tgctatgtct gttatatcag gcacaagtga aaactcgcga ccatctggta
     8521 gagatgtttc ttaagcgtat ccaaaagatt attaataacg ccaagactag actgagagaa
     8581 ttacgagaga agcatctgga gcaaacagaa gaattactag gtattctggc acaaatttta
     8641 gctgtatcaa atgaaactga agacaagaca actttagggc atcaagtaca aactctattt
     8701 gcggaacatg gtggttcaga attgctgttg aagcaatatg aggaaattgc tgcttacaat
     8761 agtaacaatc acttgccttt gatgtggcac ttttactcgc gttatcgtaa gctattgttt
     8821 gaattagtaa gttcattaga tattcactca acctctgccg atgattcact gataaatgct
     8881 ttagcatttg tattaaaaaa cgaacacaga cgtaccaaat acttatcagc agatattgat
     8941 ttaagtttta ttagcaatca atggcgttcc ttggttttta ctcggattga aaacaccgag
     9001 atgttggtaa gacaacaact agaaatttgt gtcttttctt acctagctac tgaattaaaa
     9061 acaggagatg cttgtgtagt tggttcagag agctatgcag atttccgtga ccagttgttg
     9121 agcgcttcgg aatgtacccc aatgattgaa cagtattgta acgaacttgg ttttccctcc
     9181 aacccagaag actttgttga acatttgcgt aactccttag tgcttgtcgc ggagtccgta
     9241 gaccaaatct gctcagatgg taaacaagtc acaattagca aagatggcga acccatactg
     9301 aaacggattg caccatcacc tgccccagaa ggggttgagg aattagaaga ggcaatccgt
     9361 cagaaaatac cagaacgcag tattttggat attctttgta atgttgaaca ctggttaaac
     9421 tggacacggc attttggtcc tctgtctggg aacgaaccca aaatgcagca cgcaagcgaa
     9481 cgttatatcc ttactgcctt tggttatgga tgcaaccttg gacccaatca aactgcccgc
     9541 catactaggg gcgttgttac ttctcacatg atttcttaca ctaaccgccg ccacatcagt
     9601 gtacaaaatt tggaagcggc agttcgagat atgattaacg cctacaaccg ttttcatcta
     9661 ccaactatgt ggggtactgg gaaaagagcc gctgcagatg gtagtaagtt tgaggtttat
     9721 gagaataact tacaaagcga gtatcacatc cgttatggag gttacggtgg tattgcttat
     9781 caccttgttt cggatctgac ggggtgacca aggatgctga aaggcttg
//
