LOCUS       c00710_3300027..        9438 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027965.a:Ga0209062_1007442.
ACCESSION   c00710_3300027..
VERSION     c00710_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 03:16:34
            Original ID  :: 3300027965.a:Ga0209062_1007442
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9438
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..450
                     /NRPS_PKS="Domain: Thioesterase (7-139). E-value: 6.1e-21.
                     Score: 67.6. Matches aSDomain:
                     nrpspksdomains_ctg710_1_Thioesterase.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 145.9; E-value: 1.8e-44)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg710_1"
                     /transl_table=11
                     /translation="RRQNWSCPVHLFVSASRAPQIPDYDIPLHQLPEPKFTEELRRLNG
                     IPQKVLQDPKLMELFIQTLRLDLAIVETYFYATQEQLSCPISAFGGTQDSKVSLEQLSA
                     WCDQTKSEFTLQMFSGDHFFLHSNHQQLLQAIAQKMHQLILKSVN"
     protocluster    1..9438
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[485:1607](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      486..1607
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     cand_cluster    1..9438
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9438
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     aSDomain        22..417
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg710_1_Thioesterase.1"
                     /evalue="6.10E-21"
                     /label="ctg710_1_Thioesterase.1"
                     /locus_tag="ctg710_1"
                     /protein_end="139"
                     /protein_start="7"
                     /score="67.6"
                     /tool="antismash"
                     /translation="PVHLFVSASRAPQIPDYDIPLHQLPEPKFTEELRRLNGIPQKVLQ
                     DPKLMELFIQTLRLDLAIVETYFYATQEQLSCPISAFGGTQDSKVSLEQLSAWCDQTKS
                     EFTLQMFSGDHFFLHSNHQQLLQAIAQKM"
     aSModule        22..417
                     /domains="nrpspksdomains_ctg710_1_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="ctg710_1"
                     /tool="antismash"
                     /type="unknown"
     CDS             486..1607
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:chalcone and stilbene synthase domain protein
                     (Score: 262.1; E-value: 1e-79)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg710_2"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 2.4e-10,
                     bitscore: 29.6, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 7.7e-19,
                     bitscore: 57.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYIVATSSSFPSQYYSQEVLATALKKFCLAMDLDFELDIIDRFF
                     TSVFVKGRYFTLPLDSFYDIPGPAATARAAIEASISLCEKNVLKLLEKTKLDPKEISQL
                     TCVTLTAAVPSIDARLMNRIPFSPSLKRCPIFGLGCLGGAAGVARVADYLEGHPQEAAI
                     LLSVELASALWQGSLQLDLQSMINGLPEDPSVYSDIISTIVAAALFGDGSAGVLMVGRD
                     HPLAQPGLPQVIDTRASWLPNTVHLMGMELVDTGFRSIIRLQVGDYVKAGLRQAIDSLL
                     EAHNLSVDKISRWIVHPDGPKVLDAVEEELGLDAQALKLSRETLAQAGNFLSATVLHML
                     NETMTKEPPPRGTYDLLMAMGPGFSQELILLQW"
     CDS             1635..2618
                     /NRPS_PKS="Domain: NAD_binding_4 (60-174). E-value:
                     2.7e-11. Score: 34.7. Matches aSDomain:
                     nrpspksdomains_ctg710_3_NAD_binding_4.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     189.1; E-value: 2.1e-57)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg710_3"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.1e-08,
                     bitscore: 23.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.9e-09, bitscore:
                     24.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKNKTLLITGIGDFIGLRAAEMAIQRGIKVHGLESSQDKAKKA
                     QELGAQVFVGSISNKEILEKACNGADIVFHTVSVIEAGGSMDLFRSVNVGGAVNTAKAA
                     KKAGVRAFVHLSTVMVYGFCFPNYVTEEGPLRGENNACCQTKIESEIEVLKFNNPTDFG
                     VIVIRAGDVYGPGSDVWVVRPLQYMQKKKFVLADGGRGLINYVYLDNLIDAMFLAVEKE
                     AYGEAFNITDGRQTTWKEYCTRLAEIGGFPKPVISMPALLVKTAIRRQGKKADLLPESV
                     DFITRTHAYSIEKARRVLGYEPRINFDEGMARTAEWLQKNALEVCR"
     aSDomain        1815..2156
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg710_3_NAD_binding_4.1"
                     /evalue="2.70E-11"
                     /label="ctg710_3_NAD_binding_4.1"
                     /locus_tag="ctg710_3"
                     /protein_end="174"
                     /protein_start="60"
                     /score="34.7"
                     /tool="antismash"
                     /translation="EILEKACNGADIVFHTVSVIEAGGSMDLFRSVNVGGAVNTAKAAK
                     KAGVRAFVHLSTVMVYGFCFPNYVTEEGPLRGENNACCQTKIESEIEVLKFNNPTDFGV
                     IVIRAGDVYGP"
     CDS             2615..2920
                     /NRPS_PKS="Domain: ACP (20-90). E-value: 7e-19. Score:
                     59.7. Matches aSDomain: nrpspksdomains_ctg710_4_ACP.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047:phosphopantetheine-binding domain-containing
                     protein (Score: 84.1; E-value: 9.9e-26)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg710_4"
                     /sec_met_domain="PP-binding (E-value: 5.6e-17, bitscore:
                     51.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQSISNTTVRQSYTAEDIQAWMVSHLAEQLGVEPDDIDIREPFD
                     SYGLDSMQAMLLASKAERFFGFKLSPILLWNYPTIELLAQRLAKESEDLESESLEL"
     aSDomain        2675..2884
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg710_4_ACP.1"
                     /evalue="7.00E-19"
                     /label="ctg710_4_ACP.1"
                     /locus_tag="ctg710_4"
                     /protein_end="90"
                     /protein_start="20"
                     /score="59.7"
                     /tool="antismash"
                     /translation="AWMVSHLAEQLGVEPDDIDIREPFDSYGLDSMQAMLLASKAERFF
                     GFKLSPILLWNYPTIELLAQRLAKES"
     aSModule        2675..2884
                     /domains="nrpspksdomains_ctg710_4_ACP.1"
                     /incomplete
                     /locus_tags="ctg710_4"
                     /tool="antismash"
                     /type="unknown"
     CDS             3167..5059
                     /locus_tag="ctg710_5"
                     /transl_table=11
                     /translation="MNTQELFANLTQKGVQFWADNNKLNIRSPKGVLTPELHTELVTRK
                     EELLTLLNQIDVFTRNTYVSLNQGVSLQTIGRLIGCFDQQSHKECESLIIDPKAMARKL
                     TVTFKPLPNGYKNEAIIKFREDLEMKLQSYGVTIVPWEQAIVPFCYEINFPIFKSKKTI
                     KTRVVRSEVNAVIDVERDYSPVNKLAIYIAENMYQMYCFFLLKHQQMSIPRIAKLSSWA
                     EDHVAKYIEDPTNTQVIMLTNIDKELSNFNLPYQSKIKIGLNTLTRTFSQIVIGVSNEK
                     ISILNMNLADSIYSKDESESFVLNSLIPKIYVPILPLHLNRFELEKYKPNQSIYAQNLV
                     EVSHRLAQTGLFPSGSKLSEVVKRKSHQDIVNIIVNGRTGVSYGFVAYAEAPQYIGKLE
                     ITEQEWNSLYPVEKFSADEVRQNGIGRRYVKTIIGSEYRFKQIPDIWIVSSRSGCNKTN
                     LSLESDIIRIGLTSKLFLQIPEGIDHKITDIKPSYDIYVMLAITLAAALYTPELIRNGA
                     PIIHFHGYPAFEWFKPNEYCVGVNNPSVPCGTRESGVFNFMGISSLAEKQLKNIDLVSL
                     IEPDHGTNVIANDWEYLVERLQTGCIEGQIELGGRHFAALKEKLDEKTLQDTNK"
     CDS             5126..5596
                     /locus_tag="ctg710_6"
                     /transl_table=11
                     /translation="MKKKSLKVVTFLFATFANLSFAQTVSAETTKTLTVIVNGLRNRNG
                     QVCMRIYSSQQGFPLDDTSEVQAACTQITESSVTKRFYGLKPGTYAVAVLHDEYGDHKL
                     HKDLLGIPQEGFGISNNPNVSVQTGTPKFKEASFSLKQDKTIRIIMKYSLDK"
     CDS             5792..6931
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 209; E-value:
                     1.6e-63)"
                     /gene_kind="transport"
                     /locus_tag="ctg710_7"
                     /transl_table=11
                     /translation="MCILVSKTMFVLQKMLTTKHKERQLVIKLISKWPLFLALNIGLAV
                     GATSVNSLAKFRSISQSQTPTPHLPKSQPAIIGIGALGRIQPQGEVIHLSAPYALQGAR
                     VGQLLVRKGDRVRRGQVVAILDTYASHLASLREAHTQVKVAQANLAKVKAGAKQGDINA
                     QKATIARIRAELNNAQLEYQRYQSLYENGAISASLRDSKYLVLKTTQEQLSQAKASLNS
                     IAEVRPTDVEVAQADVVKAIAAVKQAQEELELTNMRAPIDGQVLKIYTWPGEIVGNEGI
                     VEIGQTKRMYVVAEVYQTDIKKVHIGQSATITSEAFTGKLRGTVTEIGLQVSKQNIFNI
                     NPKADTDRKIVEVKIQLTLADSQRVADLTNLQVQALIHL"
     CDS             6962..8146
                     /locus_tag="ctg710_8"
                     /transl_table=11
                     /translation="MKIAMLLNIPVAYLQLTREKVRSLVALAGIAFIVVLIFMQLGFQD
                     ALYSSATQLNQHLKGDLFIISSQYESLTSQQSFPRSRLYQALAIDGVESVNALYLEFAK
                     FKNSITGRKFPIYVVGFNPEESALNYPEIQQNLKILQLPDVVLFDRNSRPEFGPIAKKF
                     EQGENVEMEIFNYNDSTGYRVKVGGLFSQGPSFGIDGNLIVSESTFLRTFQYRQAGNID
                     AGSISLKPGANIQKVLADLSTYLPEDVKVLTRQGFIDLEKHYWAVRTPIGFTFSLMVTM
                     AFVVGIVVVYQILYTNISNHLLEFATLKAMGFKNNYLLGVVFQQALLLAILGYIPGLLI
                     SYALYDVAKNATHLPVVMSFEKQIIVLLSANLMCLFSGFFSINKLRSADPVDVF"
     CDS             8173..8880
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 208.3; E-value:
                     2.1e-63)"
                     /gene_kind="transport"
                     /locus_tag="ctg710_9"
                     /transl_table=11
                     /translation="MKKTISVNIKNLNYYFGNKTLQSQVLCDINLKIRSEEIIVLTGPS
                     GSGKTTLLTLIGGLRSVQTGTLNVLGKELYGASDDKLVQVRRHIGYIFQAHNLLEFLTA
                     RQNVQMSLELHKQISAREARHRAESMLEAVKLGNRINYYPSELSGGQKQRVAIARALVS
                     RPKLVLADEPTASLDSKTGRDVVKLMQQLAKEQGCSVLMVTHDNRILDIADRIIHMEDG
                     KLLNTDFSQKYYS"
     CDS             9278..9436
                     /locus_tag="ctg710_10"
                     /transl_table=11
                     /translation="MTQTDILVTRLFDDLINKNVVIFMLFTFVIIAGLYWLMKQINLKL
                     MLSTQRYF"
ORIGIN
        1 cgccgacaga attggtcttg cccagttcat ctatttgttt ctgcaagccg tgcgccgcag
       61 ataccagatt atgatatccc gctccatcaa ctacctgaac ctaagttcac agaagaattg
      121 cgtcgcctca atggtattcc ccaaaaggtt ttacaagacc ccaagctgat ggagctattt
      181 atccagacat tacgtttaga cttggcaatt gtagagacgt acttttatgc tacacaagag
      241 caacttagct gtccaatctc tgcttttggc ggtacacagg atagtaaagt tagccttgag
      301 caacttagcg cttggtgcga ccagacaaag agtgaattta cactgcaaat gttttctggt
      361 gaccatttct tcttgcacag caaccatcag cagctgttac aggcaatagc tcaaaagatg
      421 catcaattaa tacttaaatc agttaactaa taactgttaa gtcattaagt aggttagaaa
      481 tcatcatgac ttatattgtt gccacttcca gtagctttcc ctctcaatat tactctcagg
      541 aagtactagc tacagccttg aagaaattct gtctggcgat ggatctagat tttgaattgg
      601 atattattga ccgctttttc accagtgttt tcgtcaaagg gcgttacttt acattaccac
      661 tagactcctt ctatgacata cctggacctg cggcaactgc ccgtgcagct atagaggctt
      721 ccatcagctt atgtgaaaaa aacgtactga agttgctaga gaagactaag cttgacccca
      781 aggagatatc acaactcact tgtgtaactc tcaccgcagc agttccatca atcgatgccc
      841 ggttgatgaa caggattcca ttctctccca gtctaaaaag atgtccaatc tttggacttg
      901 gctgcttagg tggagcagca ggcgtggcgc gagttgcaga ttatctggaa ggacaccctc
      961 aggaagcagc cattctgttg tctgttgagc tagcctcagc cttgtggcaa ggctccctgc
     1021 aattggatct gcaatctatg attaatggct tgccagaaga cccgtctgtc tacagtgata
     1081 ttatttctac cattgttgca gcggctttgt ttggagatgg gtcagcaggg gttttaatgg
     1141 tcgggcgtga ccatcctcta gctcaacctg ggctacctca ggtgatagat actcgcgcaa
     1201 gctggttgcc taatactgta catcttatgg gaatggagct tgtagatact ggcttccgaa
     1261 gtattattag acttcaagtg ggtgattatg tgaaagctgg cttgcgacag gcgatagact
     1321 cactactgga agctcataat ctatcggttg ataaaatctc tcgttggatt gtgcatcctg
     1381 atggaccgaa ggtacttgat gcagtagaag aagagttggg tcttgatgct caggcgctca
     1441 agctcagtcg tgaaacctta gcgcaggctg gtaatttttt atcggcaaca gtgctgcaca
     1501 tgctgaatga aaccatgacc aaagagccac cgccaagagg aacctatgac ttgctaatgg
     1561 ctatgggacc cggcttttct caagaattga ttcttttgca gtggtaaaaa actaaaattc
     1621 agaggattac cttaatgaac ctgaaaaaca aaactctctt aataacggga attggtgatt
     1681 ttatcggact gcgggccgca gagatggcga ttcaacgggg aataaaggtg cacggactcg
     1741 aaagctcaca ggataaagca aagaaagcgc aagagcttgg agcacaggtg tttgtgggca
     1801 gcatcagcaa caaggagata ttggaaaaag cctgcaatgg cgcagatatt gtttttcata
     1861 cagtatctgt tattgaggcg ggcggttcta tggatttatt tcgcagtgtg aatgtgggcg
     1921 gagcagtcaa tacagccaag gctgctaaaa aggcgggtgt cagagccttc gtccatctct
     1981 ccactgttat ggtttatggc ttctgttttc cgaactatgt tactgaggag ggacctttac
     2041 gcggcgagaa caatgcttgc tgtcaaacga aaatagaaag cgaaattgaa gttttaaagt
     2101 ttaacaatcc aacagatttc ggagttatcg taattcgagc tggtgatgtg tacggtccgg
     2161 gaagtgatgt ttgggtagtt cgtccattgc aatacatgca aaagaaaaag tttgtccttg
     2221 ctgatggagg acgcggactt atcaactatg tctacttaga caatctcata gacgctatgt
     2281 ttcttgctgt ggaaaaagag gcgtacggtg aagcttttaa tattaccgat ggccgtcaaa
     2341 ccacctggaa ggaatattgc acgcgactgg ccgaaattgg tggttttcca aaacccgtta
     2401 tttccatgcc agccctgtta gtgaaaactg caatccggcg acaaggtaaa aaggctgatt
     2461 tgttgcccga atcggttgat tttattaccc gaacccatgc ctactccatt gaaaaggcac
     2521 gacgtgtcct aggctatgaa ccacgaatta attttgatga gggtatggct cggactgctg
     2581 agtggttaca aaaaaatgca ttagaggtgt gcagatgaac cagtctattt caaatacaac
     2641 tgttagacag tcttataccg cagaagatat tcaagcctgg atggtttctc atcttgccga
     2701 acagctagga gttgaacccg acgatataga tatccgagag cctttcgata gctacggtct
     2761 agattcaatg caggctatgc ttcttgctag taaagcagaa agatttttcg gatttaagct
     2821 gtctcccatt ctcctatgga attacccaac tattgaatta cttgcccagc gcttagctaa
     2881 agaatctgaa gatttggagt cagaaagctt agaactgtga gtgtgtcaag taacttttga
     2941 ataagtgact tgacagaaca aagttttaaa gcttctaaaa ttatgagtac atcacacaac
     3001 tattctcgaa ttattatcat ttatgactaa gtgttaaaac acactctagt ctagatttga
     3061 aaattgtcac tcacagaata attcaagaga aatagtgtca aagcaaaact atttttgcct
     3121 aagttatagg acaactttac aacaacaatt tggagatttt gaaactatga atacacaaga
     3181 actttttgct aatcttaccc aaaaaggtgt tcaattttgg gcagataaca acaaattaaa
     3241 tattcgttct cccaagggag tactgacacc agaactgcac actgaattgg taacacgtaa
     3301 ggaagagttg ctaacgcttc taaatcaaat agatgtgttt actagaaata cttatgtgtc
     3361 tttgaatcag ggagtaagtc tgcaaacaat aggtcgttta attggctgtt ttgatcagca
     3421 atctcataag gagtgtgagt cactaattat cgatcctaaa gctatggctc gcaagctaac
     3481 agttacattc aaacctttgc ctaatggata caaaaatgaa gcaattatta aatttagaga
     3541 agacttagaa atgaaactac aaagctatgg tgtgacaatt gttccttggg agcaagctat
     3601 agttccattt tgctatgaaa taaattttcc tatatttaag tcgaagaaaa ccataaaaac
     3661 aagagtggtt agatctgaag ttaatgcagt aattgatgta gaaagagatt attcaccagt
     3721 aaataagctg gctatttata tagcagaaaa catgtatcaa atgtattgct tttttttatt
     3781 gaagcatcaa caaatgtcga taccaagaat tgctaagtta agcagctggg ctgaggatca
     3841 tgtagctaaa tacattgaag atcctacaaa tactcaggta attatgctca ctaatataga
     3901 taaagaacta agcaatttta atctacctta ccagagtaaa attaagattg gtttaaacac
     3961 attgactaga acattttcac agatagtcat tggagtatct aacgaaaaaa tttctatttt
     4021 gaatatgaat cttgccgatt ctatttattc taaagacgag agcgaaagtt ttgtattaaa
     4081 ttcactaatt ccaaaaatat atgttcccat acttccctta cacttaaacc gattcgagtt
     4141 ggaaaaatac aaaccaaatc aatctattta tgcacaaaac ttagtggaag tgagtcatag
     4201 acttgctcaa acaggtttat ttccttctgg ttcaaagctg agtgaagttg ttaaaagaaa
     4261 atctcatcaa gacattgtta atataattgt gaatgggaga acaggtgtct cttatggctt
     4321 tgttgcctat gctgaagctc cacaatacat tggcaagcta gaaattactg agcaggagtg
     4381 gaacagcctt tatcctgttg agaagtttag tgctgatgaa gttcgtcaaa atggcatagg
     4441 tagacggtat gtcaaaacta taataggctc agaatataga tttaaacaga tacctgatat
     4501 ctggattgtc agttctcgtt ctggttgtaa taaaacaaac ttaagtcttg aaagtgacat
     4561 tatcagaatt ggtttgacat caaagttatt tctccaaata ccagagggaa ttgaccataa
     4621 aattacagat atcaaacctt cttatgatat ctacgtaatg ctggctataa cccttgctgc
     4681 tgctttgtat acaccagaac taatcagaaa tggagcacca attatccatt tccacgggta
     4741 cccagccttt gagtggttta aaccaaatga atactgtgtt ggagtcaaca atccttcagt
     4801 accttgtggt actcgtgaat caggagtgtt caactttatg ggcatttcta gcttggcaga
     4861 gaaacagttg aaaaatatag acctagttag tttgattgaa ccagatcatg gcacaaatgt
     4921 catagccaat gattgggaat atttagtaga aagattgcag actgggtgta tagaagggca
     4981 aatcgaatta ggtggaagac attttgctgc tctcaaagag aagctagatg aaaaaacatt
     5041 gcaagataca aacaagtgat tttaagaaca atgtcatgtt ggtgagaatt accgatatac
     5101 tttctgcttt tgaataactt gtgtcatgaa aaaaaaatcc ttaaaagttg ttaccttttt
     5161 atttgctact tttgcaaact taagctttgc tcaaacagtg agtgcagaaa ccactaaaac
     5221 acttactgtg atagtaaatg gactgcgtaa ccgcaacggt caagtttgta tgagaattta
     5281 ctcgagtcaa caaggatttc ctcttgatga tacaagtgag gtacaagctg cttgcactca
     5341 gataacggaa agttctgtta ccaagcgttt ctatggtttg aaacctggaa cttatgctgt
     5401 tgctgtccta catgatgaat atggagacca caagctccac aaagacttgt taggtattcc
     5461 tcaagaaggt tttggtattt ccaacaatcc aaatgtatca gtgcaaacag gtactccgaa
     5521 gtttaaggaa gcaagttttt ctctcaaaca agataaaaca atcagaatta tcatgaaata
     5581 ttctctcgac aagtagctac tgacatcttg cattttcctg gttatagggc tggtgggagg
     5641 agatcacctt accaaagaat aagcttttgc gtcttcgatt ttcgcaacaa attcctggtg
     5701 tatgatataa gcttttcact agcactatta acatgtgaaa aatgcacatt tttttgaatc
     5761 tctaaaaccc ttgctgtatc agagttctaa aatgtgcatt ttagtaagta aaactatgtt
     5821 tgtattacaa aaaatgttga ctacaaagca caaagaaagg caactagtta taaaacttat
     5881 tagtaagtgg ccgttatttt tagcacttaa tatcggtttg gctgttgggg caacatctgt
     5941 caacagtctg gcaaaatttc gctctatttc tcaaagtcaa actcccaccc cccatcttcc
     6001 aaagagtcag ccagccatca ttggtattgg tgctctagga cgtatacagc ctcaaggaga
     6061 agtgattcac ctgtctgctc cgtatgccct tcaaggggct cgagtagggc aactcttggt
     6121 cagaaaagga gatagagttc gtagggggca agtggtagca attcttgaca cttatgctag
     6181 tcatcttgcc tctttaagag aggctcacac acaagttaaa gttgctcaag ctaatttggc
     6241 taaggtaaaa gcaggagcaa aacaaggaga catcaatgct caaaaagcga caattgctcg
     6301 cataagggct gagttgaaca atgctcagtt agagtaccag cgttatcagt ccttatacga
     6361 aaatggagca atttcagcct ctctaaggga tagtaagtac ttagtattga aaacaactca
     6421 agagcaactt agtcaagcca aagcctctct caacagtatt gcagaagtcc gtcctacaga
     6481 tgtggaggta gcgcaagcag atgttgtcaa agctatagca gcggttaaac aagcccagga
     6541 ggaactagag ctaaccaata tgcgagctcc tatagacggt caagtcctca aaatttatac
     6601 ctggccagga gaaatagttg gtaatgaggg cattgtcgaa ataggtcaaa caaaacgaat
     6661 gtatgtggta gcagaagttt accaaacaga tatcaaaaaa gtacatatcg gtcaatctgc
     6721 tactatcact agcgaagcct ttacagggaa attacgggga acagtcacag aaattgggtt
     6781 gcaagtaagc aaacaaaaca tttttaatat caatcccaag gcagatacag atcgcaaaat
     6841 agttgaggta aaaattcagc ttactttagc agatagtcaa cgagttgcag atttaaccaa
     6901 tttacaggta caagcactca ttcatcttta acttgctcag cagatatcgc tcatcttact
     6961 aatgaaaatt gccatgcttc ttaatatacc cgtagcttat ctacaactaa cacgagaaaa
     7021 agttcgctct ctggtggctt tagctggtat tgcttttatc gtcgttctta tctttatgca
     7081 attaggtttt caggatgctc tttattcaag tgctacacag ctaaatcagc atctcaaggg
     7141 agatttattt ataatcagtt cccaatacga atctttgacc tctcagcaaa gttttcctcg
     7201 ttctcgttta tatcaggcgt tagccattga tggtgtagag tcagtcaatg ctttatatct
     7261 tgaatttgca aaatttaaaa actctataac tggtcgaaag tttccaatat atgttgttgg
     7321 ttttaatcct gaagaatcag cgctgaacta ccctgaaatt cagcaaaatt taaagatact
     7381 acaacttcct gatgtagttt tattcgaccg taattctcgt cctgaattcg ggccaatagc
     7441 taagaaattt gagcaaggag aaaatgtaga aatggaaata tttaactata atgattcaac
     7501 tggctacaga gttaaagtcg gtggcttatt tagccaagga ccttcttttg gaatagatgg
     7561 aaacttaatt gttagtgaat caacgttcct tcgcacattt caatatcgtc aagctggaaa
     7621 tatcgatgcg ggttcaatta gccttaaacc tggtgctaac attcaaaaag ttttggcaga
     7681 tttatcaacc tatttacccg aagatgttaa agttctaact cgtcagggat ttattgattt
     7741 agaaaaacat tattgggctg tcagaacacc tattggtttt acatttagct tgatggtaac
     7801 gatggcattt gttgttggaa tagtcgtagt ttatcaaatt ctctatacta atatctctaa
     7861 tcacttgctt gaatttgcaa ctttaaaggc aatgggattt aaaaataatt atttattagg
     7921 tgttgtattt caacaagctt tattgttagc aattttaggt tatattccag gattacttat
     7981 ttcttatgct ctatacgatg tagcaaaaaa tgctactcat ttaccagttg ttatgagctt
     8041 tgaaaaacaa attatagtat tattgtcagc aaatttgatg tgtcttttct ctggattttt
     8101 ttctataaac aaacttcgtt ctgctgaccc tgttgatgtt ttttagttta tattacccaa
     8161 tccaattaac taatgaaaaa aacaatttct gttaacataa agaaccttaa ttactacttt
     8221 ggtaataaaa cattacaaag ccaagttttg tgtgacatta acctaaaaat aagatctgaa
     8281 gaaattattg ttttgactgg accatctggc tctggtaaaa ccactttgct aactttgatt
     8341 ggtggtttac ggtctgtcca aactggcact cttaatgttt taggcaagga gctttatgga
     8401 gcgagtgatg acaaactggt gcaagtacgt cgccacattg gctatatttt ccaagctcac
     8461 aatctgctag agtttttaac ggcacggcag aatgttcaaa tgtcacttga acttcacaaa
     8521 cagatttctg ctcgggaagc acgtcaccga gctgagagta tgctggaggc agttaaattg
     8581 ggtaaccgaa taaattatta tccgtctgaa ctttcaggtg ggcaaaagca acgggtggcg
     8641 atcgcccgtg ctttagtaag tcgtcccaag ttggtcttag ctgatgaacc aactgcgtct
     8701 ttagacagta aaacaggtcg tgatgttgtc aaattaatgc agcaattggc taaagaacag
     8761 ggctgttcgg tcttaatggt gactcacgat aaccgaattt tagatattgc agatcgaatc
     8821 atccacatgg aagatggtaa gcttcttaat acggattttt cacaaaaata ctatagctaa
     8881 atatgactat ataactgata cttaacattt aacacttctg aaataaaata cggttgcttt
     8941 gaacggagag tacatcccga tttggtagat ttattttgta gtgcgttcgc gaagcgtgtg
     9001 ctttgcactc acatcttgct cgctggatac atcacatgag ccagatactc gcactgcttg
     9061 ttccattttg gggatgcttc ctgaacagaa ggattgtttg ccattaagaa aattaggaac
     9121 tagcgaacta gcgtccatgg aaacttttct tactgaagtc ttgaaagttt taaacaatta
     9181 cagtcactgg atcatttggg ctgagttaac gattaatgct ctgtgtgcac tggaactata
     9241 cataggccaa tttaaccgct tcactacttg aaatttgatg actcaaacag atattttagt
     9301 cactcgttta ttcgatgatt taatcaataa aaatgttgta atattcatgt tatttacatt
     9361 tgtaatcatc gcaggactgt actggttgat gaagcagata aacttaaaac ttatgctctc
     9421 cactcaacgt tacttttc
//
