LOCUS       c00758_3300027..        8392 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300027965.a:Ga0209062_1008582.
ACCESSION   c00758_3300027..
VERSION     c00758_3300027..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 03:16:34
            Original ID  :: 3300027965.a:Ga0209062_1008582
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8392
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8392
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:5584]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..5584
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..8392
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8392
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..1682)
                     /NRPS_PKS="Domain: PCP (115-181). E-value: 1.2e-26. Score:
                     84.5. Matches aSDomain: nrpspksdomains_ctg758_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (193-496). E-value:
                     4.8e-155. Score: 509.0. Matches aSDomain:
                     nrpspksdomains_ctg758_1_Epimerization.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     162.4; E-value: 3.3e-49)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg758_1"
                     /sec_met_domain="Condensation (E-value: 6.1e-75, bitscore:
                     240.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.6e-16, bitscore:
                     46.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDFHKRIDNLSVKKRKLLAFELKKQLEPQDHKVILNHQRIVAYI
                     VPNQEQTLIVDDLKKFLREKLPEYMMPSAFVLLKTLPLTPNGKVDRQSLPNPEQERSEL
                     ADPFAAPRTPEEKALAQIWSQALGLKQVGIHDNFFTLGGDSILSIQVVAKAHQAGLHLI
                     ARQLFQHPTIAELAAVASITQAIQAEQEPITGLLPLTPIQHWFFEQRLPNPHHWNQAVF
                     LEIQQALSLTTLERVVQQLLVHHDVLRLHFTHDESGWQSINASLDQVVPLTGFDLSALP
                     ETEQITALEAAIAELQSSLNLSKGPLMRVTLFNLGACQPSYLFIVIHHLVIDGVSWRIL
                     LEDLETAYKQLSKGEPHQLAPKTTSFKQWAETLVDYAHSLDLQQEWEYWLAALQKPVSR
                     LPVDFLEGANTVASSRTVLVTLSAEETQALLQKLPTTHRTQINDVLLTALLQAFNQWTG
                     SRLLLVDLEGHGREELFANIDLSRTVGWFTTLFPVLLDSGESFNLEDVLKSVKEQLRTI
                     PNRGIGYGVLRYLSTNPEIARQLRSLPQPEVSFNYLSQVDQAL"
     CDS_motif       complement(93..155)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg758_1_0005"
                     /evalue="2.10E-12"
                     /label="NRPS-E6"
                     /locus_tag="ctg758_1"
                     /protein_end="530"
                     /protein_start="509"
                     /score="39.0"
                     /tool="antismash"
                     /translation="VKEQLRTIPNRGIGYGVLRYLS"
     aSDomain        complement(195..1103)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg758_1_Epimerization.1"
                     /evalue="4.80E-155"
                     /label="ctg758_1_Epimerization.1"
                     /locus_tag="ctg758_1"
                     /protein_end="496"
                     /protein_start="193"
                     /score="509.0"
                     /tool="antismash"
                     /translation="TGLLPLTPIQHWFFEQRLPNPHHWNQAVFLEIQQALSLTTLERVV
                     QQLLVHHDVLRLHFTHDESGWQSINASLDQVVPLTGFDLSALPETEQITALEAAIAELQ
                     SSLNLSKGPLMRVTLFNLGACQPSYLFIVIHHLVIDGVSWRILLEDLETAYKQLSKGEP
                     HQLAPKTTSFKQWAETLVDYAHSLDLQQEWEYWLAALQKPVSRLPVDFLEGANTVASSR
                     TVLVTLSAEETQALLQKLPTTHRTQINDVLLTALLQAFNQWTGSRLLLVDLEGHGREEL
                     FANIDLSRTVGWFTTLFPVLLDS"
     aSModule        195..1337
                     /domains="nrpspksdomains_ctg758_1_PCP.1"
                     /domains="nrpspksdomains_ctg758_1_Epimerization.1"
                     /incomplete
                     /locus_tags="ctg758_1"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(198..248)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg758_1_0004"
                     /evalue="2.00E-09"
                     /label="NRPS-E5"
                     /locus_tag="ctg758_1"
                     /protein_end="495"
                     /protein_start="478"
                     /score="29.3"
                     /tool="antismash"
                     /translation="DLSRTVGWFTTLFPVLLD"
     CDS_motif       complement(651..716)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg758_1_0003"
                     /evalue="9.80E-13"
                     /label="NRPS-E2"
                     /locus_tag="ctg758_1"
                     /protein_end="344"
                     /protein_start="322"
                     /score="40.1"
                     /tool="antismash"
                     /translation="LFIVIHHLVIDGVSWRILLEDLE"
     CDS_motif       complement(924..1025)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg758_1_0002"
                     /evalue="3.00E-05"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg758_1"
                     /protein_end="253"
                     /protein_start="219"
                     /score="16.7"
                     /tool="antismash"
                     /translation="AVFLEIQQALSLTTLERVVQQLLVHHDVLRLHFTH"
     CDS_motif       complement(1059..1088)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg758_1_0001"
                     /evalue="3.10E-05"
                     /label="NRPS-E1"
                     /locus_tag="ctg758_1"
                     /protein_end="208"
                     /protein_start="198"
                     /score="16.6"
                     /tool="antismash"
                     /translation="LTPIQHWFFEQ"
     aSDomain        complement(1140..1337)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg758_1_PCP.1"
                     /evalue="1.20E-26"
                     /label="ctg758_1_PCP.1"
                     /locus_tag="ctg758_1"
                     /protein_end="181"
                     /protein_start="115"
                     /score="84.5"
                     /tool="antismash"
                     /translation="EKALAQIWSQALGLKQVGIHDNFFTLGGDSILSIQVVAKAHQAGL
                     HLIARQLFQHPTIAELAAVASI"
     CDS             complement(1934..5584)
                     /NRPS_PKS="Domain: Condensation_LCL (8-303). E-value:
                     7.4e-56. Score: 181.1. Matches aSDomain:
                     nrpspksdomains_ctg758_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (462-864). E-value:
                     2.9e-122. Score: 399.9. Matches aSDomain:
                     nrpspksdomains_ctg758_2_AMP-binding.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     197.4; E-value: 7.9e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg758_2"
                     /sec_met_domain="Condensation (E-value: 2.9e-44, bitscore:
                     139.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-127, bitscore:
                     410.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNDIIEGFELSPQQKHLWLLQQSNLSYRAQVAVSIEGDLDVEVL
                     KIIFQNLVSRYEIFRTTFHRLDGMKFPIQAIGKCDRPHWQELNLSNLDPEKQESKIEEI
                     FRDEGHYLFDLKQDPLLRLILVTLSECRHILLITLPALSADSRTLKNIVQEISDFYNIN
                     QKIEYSEEPIQYIQFSGWQNELLRLGNTETGVKYWQKKEVSNFPNLKIPFEAQLAKHPK
                     FQPQLFIQTLHPNLVAKIKSFIQKHKVSASVFFLACWQTLLWRLSGQSDIIIGTACDGR
                     SYEDLETALGLFAKYLPIHCHLEEHYQFNQVLQQVDQSIQEAYKWQDYFDWEFIVKEGG
                     SSEPLFCFDFEQQTVQYSTNDISFTIYKQYTCIDQFKIKLSCVDQVDTFTTEYHYDSSL
                     FSRESIQRLAEQFNTLLESTISNSKAPLAELEILGQLERQQLLTELNQTRADYPKDKCI
                     HQLIEQQAERTPDNPAVVFENRQLTYRELNAQANQLAHHLRSLGIKPDVLVGICVERSL
                     EMLVGVLGILKAGGAYVPLDPTYPHDRLRFMLENSQVSILLTQQRLVQNLPKHKTPILC
                     LDTDWEAIARQSNQNPNCDVMADHLAYVIYTSGSTGQPKGVLITHRNLTHSTSARILYY
                     SESVISFLSASPFAFDSSVAAIFWTLCQGGVLSLPQENFQLDLSQFIEQIAQRRISHLL
                     CLPSLYRLILQHGEPQQLVSLRTVIVAGESCSQDLVEHHYQLLPHTSLFNEYGPTEGTV
                     WSSVYVCQNQDSQDSKAVVPIGRPIANTRIYLLDAHLQPVPMGVAGELHLSGLGLARGY
                     LKRPELTAEKFIPNPFSDEPNSRLYKTGDLARYLPNGNIEFLGRLDHQVKIRGYRIELG
                     EIEALLREHPAVHEAVIVAREDRRKPLEQNTQENIENLVKKLLSLERTLANQLLVNIEN
                     VSEDKIEKMFNNEIEMGCKKDKNLSNQSRIFTDFEISLEIKSEEFIIPPQTFQRNWILS
                     QAVDELADDLMHLNKLSRQFVSGAEILEQNNSDSKAVSENQQIMEDWQIPLMQAMASIV
                     TETHGDILEVGFGRGISATYIQELGVKSHTIIECDNDVVNAFDQWKGRYPDKNIRLIHG
                     KWQDVVNQLDIYDGIFFHTSLLNEEEFIKYVAKSVTFAEHFFPTATDHLKKGGVFTYLT
                     HEIDSFSRRHQRLVFKYFSSFTLSVVPLTLPEKTQDLWWANSMVVIKAIK"
     CDS_motif       complement(2963..3028)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg758_2_0005"
                     /evalue="1.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg758_2"
                     /protein_end="874"
                     /protein_start="852"
                     /score="39.5"
                     /tool="antismash"
                     /translation="FLGRLDHQVKIRGYRIELGEIEA"
     aSDomain        complement(2993..4198)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg758_2_AMP-binding.1"
                     /evalue="2.90E-122"
                     /label="ctg758_2_AMP-binding.1"
                     /locus_tag="ctg758_2"
                     /protein_end="864"
                     /protein_start="462"
                     /score="399.9"
                     /specificity="consensus: val"
                     /tool="antismash"
                     /translation="EQQAERTPDNPAVVFENRQLTYRELNAQANQLAHHLRSLGIKPDV
                     LVGICVERSLEMLVGVLGILKAGGAYVPLDPTYPHDRLRFMLENSQVSILLTQQRLVQN
                     LPKHKTPILCLDTDWEAIARQSNQNPNCDVMADHLAYVIYTSGSTGQPKGVLITHRNLT
                     HSTSARILYYSESVISFLSASPFAFDSSVAAIFWTLCQGGVLSLPQENFQLDLSQFIEQ
                     IAQRRISHLLCLPSLYRLILQHGEPQQLVSLRTVIVAGESCSQDLVEHHYQLLPHTSLF
                     NEYGPTEGTVWSSVYVCQNQDSQDSKAVVPIGRPIANTRIYLLDAHLQPVPMGVAGELH
                     LSGLGLARGYLKRPELTAEKFIPNPFSDEPNSRLYKTGDLARYLPNGNIEFLGRLDHQV
                     KIRG"
     aSModule        2993..5560
                     /domains="nrpspksdomains_ctg758_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg758_2_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg758_2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3116..3205)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg758_2_0004"
                     /evalue="6.60E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg758_2"
                     /protein_end="823"
                     /protein_start="793"
                     /score="50.4"
                     /tool="antismash"
                     /translation="PMGVAGELHLSGLGLARGYLKRPELTAEKFI"
     CDS_motif       complement(3722..3781)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg758_2_0003"
                     /evalue="8.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg758_2"
                     /protein_end="621"
                     /protein_start="601"
                     /score="33.6"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVLITHR"
     CDS_motif       complement(3974..4015)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg758_2_0002"
                     /evalue="3.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg758_2"
                     /protein_end="537"
                     /protein_start="523"
                     /score="20.0"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLDP"
     aSDomain        complement(4676..5560)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg758_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="7.40E-56"
                     /label="ctg758_2_Condensation_LCL.1"
                     /locus_tag="ctg758_2"
                     /protein_end="303"
                     /protein_start="8"
                     /score="181.1"
                     /tool="antismash"
                     /translation="FELSPQQKHLWLLQQSNLSYRAQVAVSIEGDLDVEVLKIIFQNLV
                     SRYEIFRTTFHRLDGMKFPIQAIGKCDRPHWQELNLSNLDPEKQESKIEEIFRDEGHYL
                     FDLKQDPLLRLILVTLSECRHILLITLPALSADSRTLKNIVQEISDFYNINQKIEYSEE
                     PIQYIQFSGWQNELLRLGNTETGVKYWQKKEVSNFPNLKIPFEAQLAKHPKFQPQLFIQ
                     TLHPNLVAKIKSFIQKHKVSASVFFLACWQTLLWRLSGQSDIIIGTACDGRSYEDLETA
                     LGLFAKYLPIHCHLE"
     CDS_motif       complement(5393..5503)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg758_2_0001"
                     /evalue="2.40E-10"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg758_2"
                     /protein_end="64"
                     /protein_start="27"
                     /score="32.7"
                     /tool="antismash"
                     /translation="YRAQVAVSIEGDLDVEVLKIIFQNLVSRYEIFRTTFHR"
     CDS             complement(5749..7641)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 614.5; E-value: 3.3e-186)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg758_3"
                     /sec_met_domain="Asn_synthase (E-value: 4.7e-76, bitscore:
                     244.8, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1.3e-47, bitscore:
                     148.9, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVAIFSNEEPISATALAKATQRLDHRGPDRQSQWIAPHQQVG
                     LGHTRLSIIDLATGDQPIANENEQLHLVVNGEFYDYERIQRELEQRGHRFRTRSDSEIV
                     LHLYEEFGPECLQHLRGEFAFILWDEPNQRLFAARDRFGIKPLFYTMIGDTLYLASEAK
                     ALFAAGVPARWDHESVFQQLFVFMNQDRTLFEGVYQVPPGYYLLATSQQTQLTRYWDLD
                     YPRTDSPIPRHTSAEYIEQLRDKLQEAIQIRLRADVPVGVYLSGGVDSSTVLSMAMKHS
                     SDPLRAFTATFDQPGYNEEPFAREMAAYVGADFQPLPLNPSDFAEHAADAAWHSEMLGT
                     NPRGVARYLQSHAVQNFGYKVVLAGEGSDEIFGGYGHVHQDSLLDNTNQPSEKATQQES
                     QKKQGRLPQNSLASLAGVKQTLGFVPSWLKKVAIERSFFYILLAPDYAAKFAQRNAYDV
                     FLNQFDVPGQILGREPVIQSMYLWSKSILPNFTLFAERLDMAHAVEVRLPYLDHHVFEL
                     VREIPVSLLAQGTREKYVLREAARPFLNETVYSRPKHPFTAPPATLTTTNQLYALIQDS
                     LRSSVMASVPFFNQVRVIELLDKLPEMSERQRIALDPTLLTLLCTYFLQSRYNL"
     CDS             complement(7629..8390)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046:Dioxygenase TauD/TfdA (Score: 365.9; E-value:
                     2.3e-111)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg758_4"
                     /transl_table=11
                     /translation="YRASPRTQISRNIYTATDYPATQSIFPHNEHAYSPTFPLKIYFFC
                     VTPAPQGGETPIGDTRKIFERIDPKIRERFTQKKVMYVRNYNDGFGLPWQTVFQTTDKS
                     VVENYCRSHGIQVEWKEENRLRTRQVSPAIFPHPRTGEKVWFNHATFFHVSTLEPTIRK
                     SLLEDFEEEDLPTNTYYGDGSPIESSVLDELRDAYSQEMIVFPWQEGDILLLDNMLAVH
                     GRRPFVGNRKIAVAMAEAFTQDQSRGDTCVV"
ORIGIN
        1 ggtagagctt ggtcaacttg gctgaggtaa ttaaaactca cctcgggttg aggtaaactc
       61 cgcagttgtc tagcaatttc tgggtttgta cttaagtagc gcagcacacc gtaaccaata
      121 ccccgatttg gaatagtgcg aagctgttcc ttaacagatt tcaacacgtc ctctaaattg
      181 aaagactcac ctgaatccaa caacacaggg aaaagtgtag taaaccaacc taccgtgcgt
      241 gacagatcaa tattggcaaa cagctcctcc cgcccatgac cctctaggtc tactaacagt
      301 aaacgcgatc ctgtccactg gttaaaagcc tgcaagagtg cggtgagtaa tacatcattt
      361 atctgcgtcc gatgggtggt gggaagcttt tgcagcaaag cttgagtttc ttcagcactt
      421 aaggtgacta gcacagtacg ggatgaagcg actgtattgg ctccctcaag gaaatctact
      481 ggtagcctag aaacaggctt ctgcagtgct gctagccagt actcccactc ttgttgcaga
      541 tctaatgagt gtgcgtaatc caccagtgtt tcagcccact gcttaaacga ggtcgttttg
      601 ggcgctagtt ggtgtggctc acctttactg agctgcttat aggctgtttc aagatcctct
      661 agcaagatcc gccaagagac accatcaatg acaaggtggt ggataacaat aaatagatag
      721 cttggctgac acgcacccag attaaatagg gtcactcgca taagtggtcc ctttgacaag
      781 ttaaggctag actgcaactc ggcaatggct gcttctaggg cagttatttg ctctgtttct
      841 ggcaaagctg acaaatcaaa tcctgtcaat ggtaccactt ggtcaaggct agcgttgatt
      901 gactgccagc cagattcatc atgagtaaaa tgtagacgca gcacatcgtg gtgtactagt
      961 aactgctgca ccactcgctc caatgtcgtc aagctaagag cttgctgtat ttctaggaag
     1021 actgcctggt tccagtgatg aggattaggc agacgctgct caaaaaacca atgttggatg
     1081 ggggttaggg gtagtaaacc agtgatcggt tcttgctcag cttggatcgc ctgagttatg
     1141 cttgccactg ctgccaattc agcaatagtt gggtgctgaa aaagttgtct agcaatgaga
     1201 tgaagtcctg cctggtgagc tttggcgaca acctgaatgc taagaataga atcgccaccc
     1261 aacgtaaaaa agttgtcgtg gatgccaact tgtttcaagc caagagcttg agaccaaatt
     1321 tgtgctagcg ctttttcctc tggcgtacga ggtgcagcaa aagggtctgc aagttctgac
     1381 ctttcctgct caggatttgg aagtgactgg cgatcaacct ttccattagg tgtcagtggt
     1441 agggtcttga gcagcacaaa ggctgatggc atcatgtact ctggcaactt ctccctgaga
     1501 aatttcttga gatcatcaac aatgagagtt tgctcttggt tagggacaat atatgccaca
     1561 atgcgctgat gattgagaat aactttgtga tcttgaggtt caagttgttt tttgagttca
     1621 aaagcaagaa gtttccgctt ttttacagag agattgtcaa tgcgtttgtg aaaatcattc
     1681 atttatatca atctttatat agaattccta ttttattttt gaaatagaag ggtggatatt
     1741 gcttatcaaa atccagatat cgtaggcagt cccgatgaaa aaatttcacc gccaagcaat
     1801 gaaaatattc tttccccact ccctactccc cactccctat tttcaagtca gagtccacaa
     1861 taatacttgt tttatcccaa ttctctatgc cctatgcccg attttaacga agaattgttt
     1921 attcccactc cctctactta atagctttga taacaaccat tgaattagcc caccataaat
     1981 cttgagtttt ctctggcagc gttaacggta caacgctaag agtaaaagaa ctaaagtact
     2041 taaaaacaag cctttgatgc ctacgactga aggagtcaat ttcatgtgtt aggtaagtaa
     2101 aaactccacc tttttttaga tgatctgtag cggttggaaa aaagtgttct gcaaacgtaa
     2161 cacttttagc aacatactta ataaactctt cttcattaag tagagatgtg tgaaaaaaga
     2221 ttccgtcata aatatctaac tggttgacaa catcttgcca ctttccgtga attagccgaa
     2281 tatttttgtc cggatagcga cctttccact gatcaaaggc gttcactacg tcattatcac
     2341 actctatgat ggtatgtgac ttaacaccta actcctgaat ataagttgct gaaattcccc
     2401 tcccaaatcc tacttctaat atatccccat gtgtttctgt aacaatactt gccatagctt
     2461 gcatcaaggg tatttgccaa tcctccatta tttgctgatt ttcagaaacc gcttttgagt
     2521 ctgaattgtt ttgttctaga atttctgccc cagaaacaaa ttgccttgat aacttgttca
     2581 agtgcattaa gtcgtctgct aattcgtcta cagcttggct gagaatccaa tttctctgaa
     2641 aggtttgcgg aggaatgatg aattcctcac ttttgatttc tagagaaatc tcaaaatctg
     2701 taaatattct actttggttg ctcaaatttt tatctttttt acaacccatt tctatttcat
     2761 tattaaacat tttttctatt ttatcttctg aaacattctc tatatttact agcagctgat
     2821 ttgctagagt tctctctaaa gataatagtt ttttaaccaa attttcgatg ttttcctgag
     2881 tattctgttc taagggtttt ctcctgtctt ctctagctac aataacagcc tcatgaacag
     2941 caggatgttc tctcagtagt gcttcaattt ctcctagttc aatgcggtaa cccctgattt
     3001 tgacctgatg gtcgaggcgt ccaaggaact cgatgtttcc attggggagg taacgtgcta
     3061 aatccccagt tttgtaaagg cgtgagtttg gctcatcact aaatgggttg ggaatgaact
     3121 tttcggcagt aagttcaggt cgcttgagat accctcgtgc caaaccaaga ccactgagat
     3181 gcagttcacc agcaacaccc atagggactg gctgaaggtg agcatccagc aaatagatcc
     3241 gagtgttagc aattgggcga ccaatgggga caacagcttt tgaatcctgt gaatcctgat
     3301 tttgacagac atatacactg ctccagactg ttccttctgt aggaccgtat tcgttaaaca
     3361 atgatgtgtg gggtagcaac tgataatggt gttcaaccaa atcttgagaa caggattcac
     3421 ctgctacaat gacagtacgt agagaaacaa gttgctgtgg ttccccatgc tgcaaaataa
     3481 gtctgtatag ggatgggaga cataataaat gcgagatgcg gcgctgagct atctgttcta
     3541 taaattgtga gagatctagc tggaagttct cctgaggaag ggagagaaca ccaccttgac
     3601 acaaggtcca gaagatggct gcaactgaac tgtcgaaggc aaagggtgaa gctgataaaa
     3661 agctgatgac tgattcagag tagtaaagaa tgcgagcact tgtagagtgg gttaggtttc
     3721 tatgggtgat tagcacaccc ttgggctgac ctgttgaccc tgaagtgtag atcacgtagg
     3781 ctaggtgatc agccatgacg tcgcagttag ggttctgatt gctttgccga gcgatcgcct
     3841 cccaatctgt gtctaggcag agtattggtg tcttgtgctt gggcaagttt tgaaccagtc
     3901 gctgctgggt caggagtatt gaaacctggg aattctccag catgaatcgt agtctatcat
     3961 gtgggtaggt tgggtctagt ggtacataag cccctccagc tttgagaata cctagtaccc
     4021 ccactagcat ctctaaagag cgctccacac aaattcctac caagacatct ggcttgatcc
     4081 caagggagcg aagatggtgt gctagttggt ttgcctgagc attaagctct cgatatgtca
     4141 gttgccgatt ttcaaacaca acagctggat tgtctggtgt gcgctcagct tgttgctcaa
     4201 tcagttggtg gatacactta tctttagggt aatctgctct tgtctgattt aactcagtca
     4261 gcagttgctg tcgctctagt tgaccaagta tctccaactc agcgagcgga gcttttgaat
     4321 tgctaatagt actttctaat aatgtattaa attgctctgc taagcgctga atggactccc
     4381 tagaaaacag actggaatcg taatgatact ctgttgtgaa agtatctacc tgatccacac
     4441 aagagagttt tattttaaac tggtcaatac aggtatactg tttgtaaatt gtaaatgaaa
     4501 tgtcgttggt agaatactgt acagtctgtt gctcaaaatc gaaacagaat aaaggctcac
     4561 tacttcctcc ttctttaact ataaattccc aatcaaagta gtcttgccat ttataagctt
     4621 cttgtattga ttgatcaact tgctgaagaa cttggttgaa ttgatagtgt tcttctaggt
     4681 gacagtgaat aggtaagtac tttgcaaaca aaccaagggc cgtttctaga tcttcataag
     4741 aacgaccatc acaagcagtg ccgatgatta tgtctgactg tccactaaga cgccaaagta
     4801 aagtttgcca gcaagctagg aagaacacag aagctgaaac tttgtgcttt tgaataaacg
     4861 attttatctt tgctactagg tttggatgga gtgtctgaat gaaaagttgg ggctggaatt
     4921 ttgggtgttt agcaagttga gcttcaaaag ggatcttcaa attggggaaa ttagacactt
     4981 ccttcttttg ccaatatttt actcctgtct ctgtattgcc taatcttaat aactcattct
     5041 gccatccaga aaattgtata tattgaatag gctcttcaga atattctatt ttctggttta
     5101 tattatagaa atcgctaatt tcttgaacta tgtttttaag cgttctacta tcagcagaaa
     5161 gtgcaggtaa agtaattaat aaaatatgcc tacattctga taatgttacc aatattaagc
     5221 gtaaaagcgg atcttgcttg agatcaaaga gatagtgtcc ttcatctcta aaaatttctt
     5281 caattttgga ctcttgtttt tcagggtcta aattgctcaa attaagctct tgccagtgtg
     5341 ggcgatcgca tttgcctata gcctgaatcg ggaatttcat tccatctaat ctatggaatg
     5401 ttgtccggaa aatttcatag cgacttacta ggttctgaaa aattattttt aatacttcta
     5461 catcgagatc tccctcaatc gaaaccgcaa cctgagcccg ataagataag ttactttgct
     5521 gcaacagcca aaggtgcttc tgctgaggtg agagttcaaa gccttctata atgtcatttt
     5581 gcatttactt aagtttctaa tttatttact gatatcttgc accattctca acaagaccca
     5641 aaaaaccggg tttctgaacc agaaattaag gtttatacga tcagtgattc tcaagaaact
     5701 cggttttaaa ctcaggtgca agttaggagt ttagtaacat ttgttgaatt acaggttgta
     5761 tcgagattgg agaaagtaag tgcataatag tgtcaaaagt gttgggtcta acgcgatccg
     5821 ctggcgctca ctcatttcgg gaagtttatc tagaagttcg atgacccgta cttgattgaa
     5881 aaatggtact gatgccataa ctgaactacg taatgagtct tgaatcaatg catataactg
     5941 atttgttgtt gttagagtgg caggtggggc agtgaaagga tgcttgggtc gggagtagac
     6001 tgtttcgttg aggaaaggtc tggctgcttc ccgtagcaca tatttctccc ttgtcccctg
     6061 agctagaagt gaaacgggta tctcacgcac caattcaaag acatggtgat ctagatatgg
     6121 caaccgcacc tcaacagcat gggccatgtc tagacgttca gcaaacaatg tgaagtttgg
     6181 taaaatcgat tttgaccaca aatacattga ttgaataact ggctcccgtc ctaggatttg
     6241 accaggcaca tcaaactgat ttaaaaaaac atcataggca ttgcgctgag caaacttggc
     6301 agcataatca ggtgcaagga gaatgtagaa aaaagaacgc tcaattgcta cttttttcag
     6361 ccatgatggc acaaatccca aagtctgctt tacccccgca agagaagcta gggagttttg
     6421 ggggagtctt ccttgcttct tttgtgactc ttgctgcgtc gctttttcac taggctgatt
     6481 tgtattgtcc aacagcgaat cttgatgtac atgaccatac ccaccaaaga tttcgtcaga
     6541 gccttcgcct gctagcacga ctttatagcc aaagttctgc actgcatgac tttgcagata
     6601 tctggcaacg cctcgtgggt tagtccctag catctcacta tgccaagccg catcagcagc
     6661 gtgttcagca aaatcacttg ggttgagtgg aagcggctga aaatcagccc caacatatgc
     6721 tgccatctca cgggcaaagg gttcttcgtt atagcctggt tgatcgaaag tggcagtgaa
     6781 tgctcgaagt gggtctgaac tatgtttcat tgccatactc agtacggtgg atgaatcaac
     6841 accgccactg agatatacgc cgactggtac atcagctcgt agcctgatct gaattgcttc
     6901 ctgtagttta tccctaagtt gttcaatgta ctcagcagag gtgtgccttg gaatagggga
     6961 gtcagttctt gggtagtcaa gatcccagta gcgagtgagc tgagtctgtt ggcttgttgc
     7021 taagaggtag taaccgggtg ggacttgata gacaccctca aacagagttc gatcctggtt
     7081 catgaagaca aataactgtt ggaaaactga ctcatgatcc cagcgtgccg gaacgcctgc
     7141 ggcaaataac gctttggctt cggatgccaa ataaagtgta tcgccgatca tcgtgtagaa
     7201 gaggggcttg attccaaagc gatcgcgtgc agcaaagagg cgttggttcg gttcatccca
     7261 taatataaat gcgaattcgc cgcgcagatg ttgcaagcat tctggaccaa attcttcata
     7321 aaggtgaagc acaatctcac tgtcagaacg agtacggaat cggtgtcctc gttgttctag
     7381 ctcacgctga atccgttcat agtcgtagaa ctccccattc actacgaggt gcaattgctc
     7441 attctcgtta gcgatcggct gatctcctgt cgccagatca ataatactaa gtcgagtgtg
     7501 acctaaccca acctgttgat gaggagcaat ccattgactt tgccgatctg gtccgcgatg
     7561 atctagccgt tgcgttgctt ttgctaaagc cgttgctgaa atcggctctt cgtttgaaaa
     7621 tatcgctact ataccacaca tgtgtcaccc ctcgattgat cttgtgtaaa agcttctgcc
     7681 atagccaccg cgatctttcg gttacctaca aatggccttc gtccatggac tgctaacata
     7741 ttgtctagca gcaatatgtc tccctcttgc catggaaaga caatcatttc ttgcgaataa
     7801 gcatcgcgaa gctcgtctaa aactgaggac tcaattggag atccatcacc ataataagta
     7861 ttagtcggca gatcctcttc ctcgaagtct tctaacaacg acttgcggat tgtcggttcc
     7921 agagttgaca cgtggaaaaa agtcgcgtgg ttgaaccata ccttttctcc agtgcggggg
     7981 tggggaaaaa tagccggact gacttgacga gttctcagac gattctcttc tttccattca
     8041 acctgaatac catgactacg gcaataattt tcaaccactg atttgtccgt agtctgaaaa
     8101 accgtctgcc aagggagtcc aaatccatca ttatagttgc ggacgtacat caccttcttt
     8161 tgtgtaaacc gctctctaat ctttggatca atgcgttcaa aaatttttcg cgtgtcgccg
     8221 attggtgtct ctcccccctg cggtgcaggc gtaacacaga aaaagtaaat ttttaaagga
     8281 aaagtgggag aataggcgtg ctcattgtgt ggaaaaatgc tttgagtagc aggataatct
     8341 gttgcagtat aaatgttacg gctgatttgg gtacgtggcg atgcacgata gc
//
