LOCUS       c00109_3300028..       13549 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300028188.a:Ga0257124_1001889.
ACCESSION   c00109_3300028..
VERSION     c00109_3300028..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 20:52:01
            Original ID  :: 3300028188.a:Ga0257124_1001889
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13549
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13549
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6612:13033]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6613..13033
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..13549
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13549
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             2..1375
                     /locus_tag="ctg109_1"
                     /transl_table=11
                     /translation="LNPGVVRMYVCGMTVYDYCHLGHARVLVIFDMVVRVLRAKGFEVR
                     YVRNITDIDDKIIVRAAELNEPFDVVTERFITAMHEDEDLLNVIRPDQEPRATGYIAEI
                     VNMIQTLEEKGFAYAAKNGDVYFRVRGFDGYGALSGRSLDALMVGARVAKDEAKDDPLD
                     FVLWKAGKPGEPSWQSPWGAGRPGWHIECSAMSTRCLGDSFDIHGGGMDLRFPHHENEI
                     AQSEGATGRKFVNTWMHNGYVQIDQEKMSKSTGNFFTIREILAQDTDASRAGEVIRFMI
                     LLSHYRSSLNFSEQGLMQARAGLERLYLVLHKGRGLNGGCDEECSDRYRVRFDEALEDD
                     FNTAAAIAVLFDAAREINRDLDANNRGIAGARIRQLRKLAGSLGLLYQEPARFLGLSGH
                     SGESEEDIDLRVGALIEQRAQARRDGNYTKADTIRLQLENQGIVLEDLEDGTTIWRRH"
     CDS             1478..3214
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 578.9;
                     E-value: 1.8e-175)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_2"
                     /transl_table=11
                     /translation="MELTGAQIVVQSLKDEGVDTVFGYPGGAALHIYDAFYAQKEVRHI
                     LVRHEQGATHAADGYARATGKPGVVLVTSGPGVTNTITGIATAYMDSIPMVILTAQVPT
                     SLIGDDAFQEVDTFGITRPCVKHNYLVRDVKDLATTIKKAFFIANSGRPGPVVVDIPKD
                     VTANKTEYLYPKTVQIRSYAPVKKGHSKQISRAAKLLLLAKRPVIYSGGGIILSGAAGE
                     LTALVDLLGYPCTNTLMGLGGLASDHPQFLGMLGMHGTYEANMAMYECDVMLAVGARFD
                     DRVTGDLKKFSPHARIIHIDIDPASIGKNVRVEIPIVGDASVVLEQLVSAIRGSADQPD
                     AESLGKWWEQIKQWQSRDSLGFEMSTEVIKPQFVVQKLHEITGGDAFVTSDVGQHQMWA
                     AQYYGFSNPRRWINSGGLGTMGFGLPAAIGVQLAHPEATVACVTGEASIMMCIQELSTC
                     KQYDLPLKIVNLNNRYMGMVRQWQEFFYDRRYSHSYMDSLPDFVELAASFGHVGVKIED
                     PADVEDALREAIATTDKLVFLDFITDQTENVYPMIAAGAGHNQMVLKPSADGSKPPERE
                     LA"
     CDS             3218..3709
                     /locus_tag="ctg109_3"
                     /transl_table=11
                     /translation="MRRILSLLVENEPGALSRVAGLFSARGYNIESLTVAPTEDESLSR
                     MTIVTRGSDEVIEQITKQLNKLIDVVRLLDLTEGRHIERELLLLKVRAQGADREEIKRL
                     VDIFRGRIIDVDEETYTIELTGPGDKLNAFIAALPSAEVYEVVRSGVSGIARGDRALRL
                     "
     CDS             3763..4779
                     /locus_tag="ctg109_4"
                     /transl_table=11
                     /translation="MKVFYDNDADLKIITGKTVAVIGYGSQGHAHANNLRDSGVDVIVG
                     LREDSGSRSKAEKAGLKVTSVHEAVASADIVMMLVPDELAADLYTESVAPNLKAGAALA
                     FAHGFNVHFGFIEPSPEIDVIMIAPKGPGHLVRSTYTEGGGVPCLIAVEQDPSGTARET
                     ALSYASAIGGGRAGVIQTTYKEETETDLFGEQTVLCGGLTSLIQAGFETLVEAGYAPEM
                     AYFECLHETKLIVDLIYEGGIANMRYSISNTAEYGDVTRGPRVITSEVKAEMKIILDEI
                     QSGKFAREWMAESRSGSKRFNGLREQGQTHQIEAVGANLRGMMPWIQKGKLVDKERN"
     CDS             4833..5471
                     /locus_tag="ctg109_5"
                     /transl_table=11
                     /translation="VIAREGWTRIAIALGVAAVIHALAGPWWALPWWLVCALVIQFFRD
                     PKRIIPMQSGIVVAPAHGRVVSIGPGQDPFSGTEAIQISIFMNIFSVHSNRIPVSGDIT
                     QRQYHPGRFFNAELDKASQENERCAISIHTDNGFDVSCVQIAGLVARRILTYVKVGDRV
                     QHGQRFGFIRFGSRVDLYLPPQSRVVASLGKWVLSGSDIIAYLPVLEKP"
     CDS             5468..6289
                     /locus_tag="ctg109_6"
                     /transl_table=11
                     /translation="MSNFRKVTSLESTDKPPKGIYILPNLFTTASLLAAFYAIIQSTVG
                     NFENAAIAVIIAAVLDSLDGRVARMTNTVSDFGKEYDSLVDLVAFGLAPALILFEWGLK
                     DLGKIGWLTAFIYVATTALRLARFNTQEISSKRYFHGLPCPAAAVLLAASVWVADSYQL
                     SGGLYTTSGLAAMFLLSLAMVSSLPYRSFKDLDLKHRVPFMAVLGLVLVFVLISFDPPR
                     VLFLAFSSYAVSGIVTWALKHRKGEKVFAPSDDEPEADDAVSGSTRDKMSN"
     CDS             complement(6305..6502)
                     /locus_tag="ctg109_7"
                     /transl_table=11
                     /translation="MVEKLVRQTAQQNLKSVAGQQARVGSQPSCDWCEVSRGNTRLHCA
                     SIPRPPFRAKPHQHQALLSR"
     CDS             6613..8160
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 446.4;
                     E-value: 2.1e-135)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_8"
                     /sec_met_domain="HMGL-like (E-value: 4.2e-103, bitscore:
                     334.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSQLIIFDTTLRDGEQSPGASMTVDEKVRIARILEKLGVDVIEA
                     GFPAASVGDFEAVQKVASQIGDSRICALARANPGDVSRAAEAIRGARASRIHTFIATSP
                     IHMKAKLRMSPEDVLEKAVAAVKQARASTDDVEFSAEDAGRSDEDFLCRIFEAVIDAGA
                     STVNVPDTVGYTMPEQFGEMFARLMNRIPNADKVVFSVHCHNDLGVAVANSLAAIKAGA
                     RQVECTINGLGERAGNASLEEIVMAVRTRQDFFPCDSRLDTTHILAASRLVSNITGFPV
                     QPNKAIVGANAFAHEAGIHQDGVLKQRDTYEIMRAEDVGWSANQIVLGKHSGRNAFRER
                     MVALGIEFSSEAELNLAFDRFKELADKKHEIFDDDLQVLAGDSAASHRDETLRFVSLKT
                     VSQTGDAPVAELTLEKAGSEETAKTTGDGLVDASFRAVDDIVPGNRALLLYSVNAITAG
                     SDSQGEVSVRLQENGRIVNGQGTDTDIVVASVKAYVNALNKLQMSPQRFNPQSGDTV"
     CDS             8173..8880
                     /locus_tag="ctg109_9"
                     /transl_table=11
                     /translation="MRSRSQYLREMGLTPWALTTDTRGIASQHVEPASSDVEPLGKVPP
                     SGWASLQQQVGNCTRCNLHTTRKTTVFGEGDPKADWLLVGEAPGAEEDRQGLPFVGRAG
                     QLLNRMLFSVDLARDEVFVANVLKCRPPDNRDPFGEEVSTCVSFLHQQVTFIQPKIILA
                     MGRFAAQALLRTDQTIGQLRGRIHRYPAYDIPLVVTYHPAYLLRSPQAKAKAWDDLILA
                     LAEFEGAAGSENV"
     CDS             8976..9782
                     /locus_tag="ctg109_10"
                     /transl_table=11
                     /translation="MLMLPRKNWAGSGEAGVKALASHTGLKAWFDGPLGKTVSRSAVEK
                     SSELIPRTYYPTGLQLGPGPEDFLSKVDLGLAIYSPSVRASSPQHVVTTASEALPFSAR
                     SIDLLILPHTLDFSNEPHRVLREVGSILAAEGILVVCGFNRWSLWGLRRAVTARPRPSP
                     WSGDFLSPARVQDWMRLLGLEILGGKMMFYQPPVSATGLLRKTDFLEKAGDRWWPLLGG
                     IYLLVARKKRLGLTGTKIRMARHRPFGIDAMAPTIPRQTKIRGPRL"
     CDS             9779..10252
                     /locus_tag="ctg109_11"
                     /transl_table=11
                     /translation="VKTETADEGEVRIYTDGACRGNPGIGGWGVLIIGESSQTELLGAE
                     PATTNNRMELKAAIEGLEAVGASQPVAVYTDSQYVRNGITDWMTKWKRNGWRTASRKAV
                     KNQDLWEALDNARQARSVSWHWVRGHSGHPQNERADALANLAIDDYLKDGERN"
     CDS             10249..10974
                     /locus_tag="ctg109_12"
                     /transl_table=11
                     /translation="LTTRLVVLDTETTGLDATAGHRVIEVGGVAISDRKHSDEQFHSYL
                     NPERSIDAGALEVHGITESFLADKPLFKDILESFVEFVTGAELVIHNAPFDLGFLNNEL
                     ELAGDPRRLEDFCTVTDTLKLARELHPGQRNSLDALCRRYGVDNSGRTLHGALLDAEIL
                     ADVYLAMTGGQTDLQLEGVSGQIGMDRRPGRSGSNAGRNFAIIPASNEELVAHRKWVEL
                     LGASSVWNSVDSPGDNESG"
     CDS             11099..13033
                     /NRPS_PKS="Domain: AMP-binding (81-520). E-value: 2.5e-98.
                     Score: 321.0. Matches aSDomain:
                     nrpspksdomains_ctg109_13_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     309.4; E-value: 6.3e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_13"
                     /sec_met_domain="AMP-binding (E-value: 5.8e-114, bitscore:
                     370.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDSIIHKVNSNFAQDAHINEEQYRHMYQQSIADPDSFWADQAEK
                     FVSWFSPWHTVSNWDYHTGDIRWFEGATLNVSYNCIDRHLETRSDQVAIIWEGDDPTDD
                     KKLTYRQLHDQVCRFANVLKDRGVSKGDCVSIYMPMIPEAAVAMLACARIGAIHSVVFG
                     GFSPDALRDRILDSDCRVVITADEGPRGGKAVPLKANVETALAGCPDVHTTIVVRRTGK
                     DVPASASRDVWYDEAMAVASPDCDPEPMGAEDPLFILYTSGSTGKPKGVLHTCGGYQLY
                     TAMTHRYVFDYHDGDVYWCTADVGWITGHSYIVYGPLTNGAITLMFEGVPTYPDASRFW
                     QVVDKHQVNIFYTAPTAIRALMGQGNQPVDSTSRTSLKLLGTVGEPINPEAWEWYFNTV
                     GDGRCPVVDTWWQTETGGILITPLPGATDLKPGSATRPFFGIEPALLNADGQVLEGAAE
                     GNLVITGSWPGQMRTIYGDHERFIQTYFSAYPGYYTTGDGARRDDDGYYWITGRVDDVI
                     NVSGHRMGTAEVESALVSHEQVAEAAVVGYPHEIKGQGIYAYVTPMAGVTPSEELRRGL
                     IAQVRKEIGPIASPDIIQWAPGLPKTRSGKIMRRILRKIAANELENLGDTSTLAEPAVV
                     DELIKNRVN"
     aSDomain        11342..12658
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg109_13_AMP-binding.1"
                     /evalue="2.50E-98"
                     /label="ctg109_13_AMP-binding.1"
                     /locus_tag="ctg109_13"
                     /protein_end="520"
                     /protein_start="81"
                     /score="321.0"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="DRHLETRSDQVAIIWEGDDPTDDKKLTYRQLHDQVCRFANVLKDR
                     GVSKGDCVSIYMPMIPEAAVAMLACARIGAIHSVVFGGFSPDALRDRILDSDCRVVITA
                     DEGPRGGKAVPLKANVETALAGCPDVHTTIVVRRTGKDVPASASRDVWYDEAMAVASPD
                     CDPEPMGAEDPLFILYTSGSTGKPKGVLHTCGGYQLYTAMTHRYVFDYHDGDVYWCTAD
                     VGWITGHSYIVYGPLTNGAITLMFEGVPTYPDASRFWQVVDKHQVNIFYTAPTAIRALM
                     GQGNQPVDSTSRTSLKLLGTVGEPINPEAWEWYFNTVGDGRCPVVDTWWQTETGGILIT
                     PLPGATDLKPGSATRPFFGIEPALLNADGQVLEGAAEGNLVITGSWPGQMRTIYGDHER
                     FIQTYFSAYPGYYTTGDGARRDDDGYYWITGRVDDVINVSG"
     aSModule        11342..12658
                     /domains="nrpspksdomains_ctg109_13_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg109_13"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       11867..11920
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg109_13_0001"
                     /evalue="8.10E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg109_13"
                     /protein_end="274"
                     /protein_start="256"
                     /score="24.6"
                     /tool="antismash"
                     /translation="FILYTSGSTGKPKGVLHTC"
     CDS_motif       12626..12688
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg109_13_0002"
                     /evalue="4.10E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg109_13"
                     /protein_end="530"
                     /protein_start="509"
                     /score="13.2"
                     /tool="antismash"
                     /translation="TGRVDDVINVSGHRMGTAEVES"
     CDS             13177..13548
                     /locus_tag="ctg109_14"
                     /transl_table=11
                     /translation="MRHYEVVFLVHPDQSEQVPAMVEKYRGLIEGNGGQIHRCEDWGRR
                     PLAYTIGKVHKAHYVLMNVEIDQPTMDEMANMFKFSDAVIRNLVIRRKEAVTEASALVV
                     EAGAGAVDSEQKPAEVAPET"
ORIGIN
        1 gttgaaccca ggggtagtgc gcatgtatgt ctgcggtatg acggtctatg attattgcca
       61 cttgggtcac gcgagggttt tggttatttt tgatatggtg gttcgggttc tgagggccaa
      121 aggattcgag gtccgctatg tacgcaatat aactgatatc gatgacaaga ttatcgtccg
      181 ggcggcagag ttgaacgaac ctttcgatgt ggtgacagaa cggtttatca cagcgatgca
      241 cgaggacgaa gatctgttga atgttatccg tccagaccaa gaaccccgtg ccactggata
      301 tattgctgag atcgtgaata tgattcaaac ccttgaagaa aagggttttg cctacgcggc
      361 aaaaaatggc gatgtgtatt tccgtgtgcg tggattcgat gggtatggcg ctttgtcagg
      421 tcgctcgctc gatgctctga tggtaggagc ccgggtagca aaagacgagg caaaagatga
      481 tccgcttgac tttgtcctgt ggaaagcagg caagcctgga gagccgagct ggcaatcgcc
      541 ctggggggct ggtcgtccgg gctggcacat cgagtgttcg gcgatgtcaa ctcgctgcct
      601 tggtgatagc ttcgatatcc atggtggcgg gatggatttg cgttttccgc atcatgagaa
      661 tgaaatcgcc caaagcgaag gggcaaccgg tcgcaagttc gtaaacacat ggatgcataa
      721 tggttacgtt caaattgacc aagaaaaaat gtccaagtca acgggcaact tttttacgat
      781 ccgcgagatc cttgctcagg atacggacgc ctcccgcgct ggagaggtga tacgttttat
      841 gatcctgcta agccattatc gcagctcttt gaatttttca gagcaaggcc tgatgcaggc
      901 gcgtgctggt ctggagcgac tgtatcttgt gcttcataag ggtagggggt tgaatggcgg
      961 gtgtgacgaa gagtgctcgg atcgttaccg cgtgcggttt gatgaggcgc ttgaagacga
     1021 tttcaatact gctgctgcaa tcgctgtcct ttttgatgcc gcaagggaga tcaaccggga
     1081 cttggatgcc aataataggg gcattgccgg ggcgagaatc agacaattac gcaaacttgc
     1141 tggttcgctg ggattacttt atcaggagcc tgcccggttt ctcgggttgt cgggccactc
     1201 gggcgaaagc gaggaggata ttgaccttag agttggcgct ctgattgagc aacgcgccca
     1261 ggctcggcgc gatggcaact acacgaaggc agacacaatc cgcttgcagt tggaaaatca
     1321 gggcattgtc cttgaggatc ttgaggacgg aacgacaata tggcgccggc attgaattta
     1381 cagcatgcta ccgaactgtt tataatttaa gttgttggtt cgtttctgat ttctatcggc
     1441 cactaggcaa ctcccactct tctaccgagg ttcatatatg gaactgaccg gcgctcagat
     1501 cgtcgttcaa agcctgaaag atgaaggcgt cgatactgtt ttcggttatc ccggaggcgc
     1561 ggcactgcac atctatgatg ccttttatgc ccaaaaggag gtaaggcata ttctggttcg
     1621 ccacgagcag ggagcaaccc acgctgctga cggatacgcc cgtgctaccg gaaaacctgg
     1681 cgtcgtgttg gtcacgtcag gccctggcgt cacgaatacg ataaccggta ttgctaccgc
     1741 ctatatggat tcgatcccga tggtcatcct gaccgcccag gtgccgacga gtctgatcgg
     1801 ggatgacgcc tttcaggagg tcgatacttt cgggatcacc cgaccgtgtg tgaagcataa
     1861 ttatctcgtt cgcgacgtca aggatctcgc aacaacgatc aaaaaagcgt ttttcattgc
     1921 gaattcaggc cggcccggtc cggtagttgt tgatatccct aaggacgtca cagcgaataa
     1981 gactgagtat ctttatccga aaaccgtgca gatccgctct tatgccccgg tcaaaaaagg
     2041 gcattccaag cagatttcgc gcgcagctaa gctactgctt ttggccaaac gtccggtgat
     2101 ctactctggg ggcggtatca ttctttccgg tgcggcgggc gagcttacag ccctggtcga
     2161 cctactgggg tacccatgca caaatacgtt gatggggctg ggcggactgg cgtcggatca
     2221 tcctcagttt ttgggcatgc ttggcatgca cggaacctac gaagcaaaca tggcgatgta
     2281 cgagtgcgat gtaatgcttg cggtaggcgc ccgtttcgat gatcgagtga ccggagacct
     2341 taagaagttt tctccgcacg ccagaattat ccacattgat atcgacccag catcgattgg
     2401 caagaacgtc cgggtagaaa ttcctatcgt gggcgatgcc tcggtagtgc tggaacaact
     2461 tgtgagcgcg atccgaggga gcgcggatca gccggatgcc gagagtcttg gcaaatggtg
     2521 ggaacagatc aaacagtggc aaagccgcga ctcactcggg tttgaaatga gcacagaggt
     2581 gatcaaacct cagttcgtag tccagaaatt gcacgaaata acaggtggcg atgcgtttgt
     2641 tacctcggac gtgggccagc atcagatgtg ggccgcccag tactatggtt ttagcaaccc
     2701 gcgtcgctgg atcaattccg gtggacttgg gactatgggc tttggattgc ctgctgccat
     2761 tggcgtccaa ttggcccatc ctgaggccac agtagcttgc gtaaccggtg aggccagcat
     2821 catgatgtgc atccaggagt tatcaacctg caagcagtat gatctgccac ttaaaatcgt
     2881 taatttgaac aatcgataca tgggcatggt tcggcaatgg caggagtttt tctacgatcg
     2941 gcgctactca cattcatata tggactcgtt gccagatttt gttgagcttg ctgccagttt
     3001 tggacacgtc ggtgtcaaaa tcgaggatcc agcagatgtt gaggacgctc tgcgtgaagc
     3061 catcgctacc acggataaac tggtctttct cgacttcata acggaccaga ccgaaaacgt
     3121 atatccaatg attgctgccg gtgccgggca taaccaaatg gtattaaagc cgagcgcgga
     3181 cggttcgaaa ccccccgagc gggagctggc ctgacagatg aggcgaatcc tctctttact
     3241 ggtagaaaac gagcctgggg ccttatccag ggtcgctggt ctcttctcgg cgcgaggtta
     3301 taacatcgag tcgcttacgg ttgccccaac tgaggacgag tccctctctc gaatgactat
     3361 tgtcacccgg ggttctgacg aggtgattga gcagattacc aagcaactta ataaattaat
     3421 tgatgtggtt cgcttactcg atcttactga ggggcgacat attgagcgcg aactgttgct
     3481 actgaaggtt cgtgcccaag gtgcagaccg cgaggaaatc aaaagactag tggatatatt
     3541 ccggggccgt attatcgacg tcgatgagga aacctacact attgaactca ccggcccggg
     3601 tgataagctg aatgcgttta tagctgcctt gccttcagcg gaagtttacg aagtagtccg
     3661 tagtggggtg tccgggattg ctagaggtga tcgagccttg cgtctgtagg gccacggatt
     3721 cattaattta tgaacgtcag cgtataaaga ggaagcgcca aaatgaaagt tttttatgac
     3781 aacgatgccg atctgaagat tattaccggc aaaaccgtcg ccgtgatcgg gtatggctcc
     3841 caaggacatg ctcacgccaa caatcttcgc gacagcgggg ttgatgtgat cgtaggtctg
     3901 cgcgaggact caggttcccg gagtaaggca gagaaagctg gcttgaaagt cacttcggtc
     3961 catgaggcgg ttgcatcggc cgatatagtg atgatgctgg taccggacga actggccgca
     4021 gatttatata cggagtccgt tgctcccaat cttaaggccg gtgccgctct ggccttcgcc
     4081 catgggttta atgtgcattt tggttttatt gaacccagcc ctgaaattga cgtaattatg
     4141 attgcaccca aaggccctgg gcacctggtt cgatcaacct acacggaagg gggcggtgtg
     4201 ccctgtctga tcgcggtaga gcaggatccg agcggcacag cccgcgaaac agcactgtcc
     4261 tacgccagtg ccattggcgg tgggcgtgcc ggggttatcc aaacgacgta taaagaagag
     4321 accgagactg atctatttgg ggagcagacg gtcttgtgtg gcggcttaac atcgttgatc
     4381 caagctggat ttgaaacctt ggtcgaggcc ggatacgcac ctgagatggc ctattttgaa
     4441 tgcttgcatg agaccaaatt gatcgtcgat ctcatctacg aaggcgggat tgcaaatatg
     4501 cgctactcca tctccaatac cgcagaatat ggtgacgtca ctcgagggcc tcgcgttatc
     4561 acttcagaag ttaaggccga aatgaaaatc atccttgacg aaatacagtc cggcaaattt
     4621 gcccgtgagt ggatggcaga gagccgctct ggcagcaagc gatttaacgg gctgcgagag
     4681 caaggtcaaa ctcatcagat agaggcggtc ggtgcgaacc tgcgcggcat gatgccgtgg
     4741 attcaaaaag gtaagctggt tgacaaggag cgcaactgag ttacgcaact tggggcacta
     4801 acagttgctg tcgcctcgag gtgggttagg ccgtgattgc ccgagagggc tggacccgaa
     4861 ttgcgattgc tctgggagtc gcggcggtaa tacatgcgct ggccgggcct tggtgggcac
     4921 ttccctggtg gcttgtctgc gcgctggtta ttcagttttt ccgagatccc aaacgcatca
     4981 tccccatgca atccgggata gttgttgccc ctgcccatgg ccgggtggta agcattgggc
     5041 cgggccaaga tccgttcagc ggtaccgagg caatacaaat cagcatcttc atgaatatat
     5101 tctctgttca ctcaaaccgg attccggtga gcggcgatat aactcaacgc cagtatcatc
     5161 ccgggcggtt ctttaacgcc gagttggata aggcctccca ggaaaacgaa cgctgcgcga
     5221 tcagtatcca cacggataat ggttttgatg tcagttgtgt tcagattgcc ggcttggttg
     5281 cacggcggat actgacttac gtgaaagttg gcgatcgagt tcaacatggc caacgatttg
     5341 gatttatcag gtttggctcg cgagtcgacc tgtacctgcc cccgcaaagc cgtgtggtag
     5401 ccagtctcgg taaatgggtc ttgtcgggca gtgatatcat tgcctaccta cctgtgctag
     5461 agaagccatg agtaattttc gaaaggtcac gtcccttgaa tcgacagata aacccccaaa
     5521 ggggatttat atactgccga atctttttac cacagcgagc ctattagcgg ccttttacgc
     5581 cattattcaa tcaacggttg gcaactttga gaatgcagcg attgcagtga ttatcgctgc
     5641 agtgcttgac tcgttggatg gccgtgtcgc acggatgacc aataccgtaa gtgatttcgg
     5701 caaagagtat gactcgctgg tagatctggt cgcttttgga ttggctccgg ccttgatcct
     5761 ttttgagtgg ggactgaaag accttggaaa aattgggtgg ttgacagcat ttatttatgt
     5821 tgcaactacc gcgctgagat tggcccgctt caacactcag gaaatctcga gtaaacggta
     5881 ttttcacggc ttgccgtgcc ctgcggccgc ggttcttcta gccgccagtg tctgggttgc
     5941 agatagttac caactttccg gaggcctgta cacaacttct gggttggcgg ccatgttttt
     6001 gctttccttg gctatggtca gcagtttgcc ttatcgcagt ttcaaagatc tggacctcaa
     6061 acaccgggtc ccatttatgg cggttttggg attggtactg gtattcgttc taatctcgtt
     6121 tgatccgccg cgggttcttt ttttggcgtt tagctcctac gcggtttcgg gaatcgtgac
     6181 ttgggctcta aaacatcgca agggcgaaaa agtttttgca ccatcagacg atgagcccga
     6241 ggcggacgat gcggtctcag gatcgactcg tgacaagatg tctaattagc atgaggcaat
     6301 tgaattaacg gctgagtagg gcttggtgct gatgaggctt tgccctaaat gggggacggg
     6361 gtatactggc gcaatgcaac cgcgtatttc ccctcgaaac ttcgcaccaa tcacaggacg
     6421 gctgcgaccc gacgcgcgcc tgctgaccag ccacgctctt cagattctgc tgcgccgttt
     6481 ggcgcactaa cttctcaacc atttatcact ccgcaacatc acagccgccg ctgctaaagc
     6541 gaacggctat gattgcgggt tatccgctgc tgtttcagct gaaaacacaa taccagcttt
     6601 ggagagttga gtatgagtag ccaactaatt atttttgaca ccaccttgcg agacggggag
     6661 caaagcccgg gcgcttcgat gacagtggac gagaaggtgc gtatcgcacg cattttagaa
     6721 aaactgggag tcgacgtgat tgaagccggg tttcctgccg ccagcgtggg cgatttcgag
     6781 gccgttcaga aggttgcgag ccaaatcggg gatagccgta tttgtgcctt ggctcgagca
     6841 aatccaggcg atgtgtctcg cgccgctgag gcgatccgtg gggcccgcgc ttcgcggatt
     6901 cataccttca ttgcgacctc tccaattcac atgaaagcta agctacggat gtcccctgaa
     6961 gatgtactcg agaaagctgt agcagctgtt aagcaggccc gagccagcac tgatgatgtc
     7021 gagttttcag cagaagatgc tggtcgatcg gatgaggatt ttctttgccg aatatttgag
     7081 gccgtgatcg atgctggtgc gagcaccgta aacgttcccg acacagtcgg ctacaccatg
     7141 cctgagcagt tcggcgagat gttcgcaaga ttgatgaacc ggattccgaa tgccgataag
     7201 gtagtctttt cggtgcactg tcataacgat ctaggtgtcg cggttgcgaa ttccttggcc
     7261 gcgattaagg ccggggcccg gcaggttgaa tgtacgatca atgggctcgg cgagcgtgcc
     7321 gggaacgcct cccttgagga gatcgtaatg gccgtgcgca cccgtcagga ttttttcccc
     7381 tgtgacagca ggctcgatac cacccacatt cttgctgcca gtcgtctggt ttccaatatc
     7441 acaggtttcc cggtgcaacc aaacaaggcg atcgttggtg ctaacgcatt cgctcacgag
     7501 gcggggatac atcaagatgg cgtgctgaaa cagcgtgata cctacgagat catgcgtgcc
     7561 gaggacgtcg gctggagcgc caatcagatt gtgcttggaa aacattcggg ccggaatgca
     7621 ttcagggaac gtatggttgc tttgggtatt gagttctcga gcgaggcgga attgaatctg
     7681 gcgttcgacc gttttaaaga gctggccgat aaaaaacatg agatttttga tgatgatctt
     7741 caagtgttgg ccggggacag cgccgcttca catcgcgacg aaaccctgcg gtttgtttca
     7801 ttaaaaaccg tttcccagac gggcgatgct ccggtagctg aattgaccct tgagaaggct
     7861 ggctctgaag agaccgccaa gacaaccggc gatggtttgg tggatgcgtc ctttagggca
     7921 gttgacgaca ttgtgcctgg aaatcgtgca cttctactct attcggttaa tgccattaca
     7981 gcagggtccg attcacaagg cgaggtcagt gtccggctac aggaaaacgg gcgtatcgtt
     8041 aacgggcaag gtaccgatac agatatcgtt gttgcatcgg tgaaggcgta tgtaaacgcc
     8101 ctgaataagt tgcagatgag cccccaacga tttaatccgc aaagtggcga taccgtttag
     8161 gacatcgggc cgatgaggag ccggtcccag tatcttcgtg agatgggatt gacaccatgg
     8221 gccctgacta ctgacacgcg aggtatcgcc agtcagcatg tcgaaccagc ctcgagcgat
     8281 gtagagcctt taggaaaggt accaccttcg ggttgggcct cattacagca gcaggtaggt
     8341 aattgtacga ggtgcaacct acataccacc cgcaaaacaa cggttttcgg cgaaggagat
     8401 cctaaagcgg actggctgtt ggtcggtgag gcgccgggcg ctgaggagga ccggcagggg
     8461 ctgccctttg tagggcgcgc tggtcaatta ctgaatcgaa tgttattcag tgtagatctc
     8521 gcgcgcgatg aggtttttgt tgccaacgtt cttaagtgtc gaccgcctga taaccgggat
     8581 ccgtttggcg aagaggtgag cacgtgtgtg tcattcctgc atcaacaggt cacgtttatt
     8641 caacctaaaa ttattctcgc aatggggcgc tttgccgctc aggcgctact tcggacggat
     8701 cagaccatag gccaacttcg agggcggatc caccggtatc ctgcctatga catcccattg
     8761 gtggttacgt atcacccggc atatctttta cgttcaccac aagccaaagc gaaggcctgg
     8821 gacgacctga tccttgccct ggctgaattc gaaggggcgg caggtagtga gaatgtttga
     8881 caatccggga agttgcccgg cccgcctgcg tacctgcggg gccggcgggc gaggttccct
     8941 ggaattgcgc atctcccgcg cgtcttggac tgcgcatgtt aatgctgcca cgtaaaaact
     9001 gggcgggatc aggtgaggcc ggtgtcaagg ccttagccag ccacactggg ctcaaggcct
     9061 ggtttgatgg acctctggga aagactgttt cacggtctgc cgttgaaaaa agttctgaat
     9121 taataccgcg cacctattat ccgacagggc tgcaactggg gcctggtcca gaagattttc
     9181 tttcaaaggt ggaccttggg ctcgccattt attctcccag cgtccgcgcg tcgagtcctc
     9241 agcacgtagt caccaccgca agcgaggcac ttccatttag tgcgcgctct atcgatttac
     9301 ttatcctccc tcacacgctg gatttttcga atgaaccgca tagggtcctg cgcgaggtgg
     9361 gctcgattct ggcggcagag gggattctcg tcgtttgtgg ttttaatcga tggagtctgt
     9421 ggggtctgag gcgggctgta actgctcgcc cgaggccctc gccctggagc ggcgatttcc
     9481 tgtctcctgc aagggtccaa gactggatgc gcctgctggg tttggaaata ctaggcggta
     9541 agatgatgtt ctatcagcct cccgttagcg cgacgggcct gcttcgcaaa accgactttc
     9601 tcgaaaaggc gggcgatcgc tggtggccgc ttctcggtgg gatctacctg ctcgtcgccc
     9661 gtaaaaaacg actgggactc accggtacca agatcagaat ggcgaggcat cggccgttcg
     9721 gcatcgatgc gatggcacct acaattcctc gccaaactaa gataagaggg cccagattgt
     9781 gaaaacggaa accgcagacg aaggagaagt tcgcatttat accgacggcg cctgtcgcgg
     9841 gaacccggga atagggggct ggggcgtact cattattggc gaatcctcgc aaacagagct
     9901 tttaggggct gaaccggcta caaccaacaa ccgtatggaa cttaaagcgg cgatagaagg
     9961 tcttgaagca gtaggggcta gccaaccggt cgcggtctat acagactcac agtatgttcg
    10021 taacggcatt accgactgga tgactaagtg gaagcgaaat ggctggcgta ccgcctcgcg
    10081 caaagcggtc aaaaatcagg acttatggga ggcattagac aatgcaaggc aggctcggtc
    10141 agtcagttgg cactgggtcc ggggccatag tggacaccca caaaacgaac gggccgatgc
    10201 tctggcgaat ctggcaatag atgattattt aaaggacggg gagagaaatt gactacacga
    10261 ttggttgttt tggatactga gacgacagga cttgatgcaa cggccggcca tcgggtgatc
    10321 gaagtgggcg gcgtagctat ttcggatcga aagcacagtg atgagcaatt tcattcttac
    10381 cttaaccctg agcgcagcat cgatgctggc gctctcgaag tccacgggat cacagaatct
    10441 tttctcgccg ataaaccatt gttcaaagat atcctggaat cgtttgtcga gtttgtgacg
    10501 ggcgcagagt tggttattca taatgccccg tttgacctgg gttttcttaa taatgagctc
    10561 gagttggcgg gggacccccg caggcttgag gacttctgta cggtaacaga cactctgaag
    10621 ttggcccggg agcttcaccc ggggcagcgc aacagcttag atgctttatg tcgccgttat
    10681 ggcgtagata actccggtcg aacccttcat ggggcactac ttgatgctga aattctggcg
    10741 gatgtttact tggcgatgac cggtggacaa accgatctgc agctagaggg ggtttcgggt
    10801 cagatcggga tggatcggcg accgggcagg tctggcagta acgccgggcg gaatttcgcg
    10861 ataattcccg cctcgaatga agagttggtt gcccatcgca aatgggttga actgttgggc
    10921 gcaagcagcg tctggaattc agtggattcg cctggcgaca atgaatcggg ctgaaatatc
    10981 ctgatggaag agtcccgcag gcctttggct ctacttttta acttaagcat ccattggctt
    11041 aaaatacccg aagaagggag agaatgaatg tcaattgatc aaagcaaagg agcgtcagat
    11101 gagtgacagt attattcaca aagttaattc aaactttgcg caagatgccc atatcaatga
    11161 agagcagtat cgacatatgt accagcaatc aatcgcggac ccggatagtt tttgggcgga
    11221 tcaagctgag aaatttgtca gttggtttag cccctggcat acggtaagca attgggacta
    11281 ccacaccggg gacatccggt ggttcgaagg ggcgacccta aacgtttcct ataactgtat
    11341 tgatcggcac ctcgaaaccc gatccgacca ggtggcaata atctgggaag gtgacgatcc
    11401 gaccgacgat aagaagttga cttaccggca gctgcatgac caggtttgcc gatttgcgaa
    11461 tgttcttaag gatcggggtg tcagcaaggg cgattgtgtg tccatttaca tgcctatgat
    11521 tccagaagcc gcggtggcga tgttggcctg cgcacgtatt ggcgcaattc actcagtcgt
    11581 ttttggcgga ttctcgccgg atgcgctacg ggatcgaatc ctggattctg actgccgggt
    11641 ggtaattact gcggacgaag ggccacgcgg cggcaaggcg gtacccttaa aggctaatgt
    11701 ggagacagca ctcgccggat gtccggatgt ccacacgact attgtggtgc ggcggaccgg
    11761 caaagatgtg cctgccagtg ctagccgtga tgtctggtat gacgaagcta tggcagttgc
    11821 atcgcctgat tgtgatccgg agccaatggg tgccgaggat ccacttttca tattgtatac
    11881 atccggctcg accgggaagc caaaaggagt tctacatacc tgcggcggat accaactgta
    11941 caccgcgatg acccatcgct atgtgtttga ctatcacgat ggcgatgtct actggtgtac
    12001 cgctgacgtc ggctggatca ctgggcacag ctatattgtc tatggccccc tgaccaacgg
    12061 agcgataacc ttgatgttcg agggggtgcc tacctacccg gatgcctcgc gtttctggca
    12121 agtggtagat aaacatcagg tgaacatctt ctacaccgcg cccactgcca tccgggcatt
    12181 gatggggcaa ggtaaccaac cggtcgattc gaccagccgc accagtctca agctgttggg
    12241 aacggtagga gagccgatta atccagaggc atgggagtgg tatttcaata ccgtcggcga
    12301 tgggcgttgc ccagttgtgg atacctggtg gcagacagaa accggtggaa ttttgattac
    12361 cccgttgcca ggggcgaccg accttaaacc gggatcggcc acacgaccat ttttcggaat
    12421 cgaacctgcc ttgttgaacg ccgacggcca ggttctcgaa ggcgcggccg agggcaacct
    12481 ggtgatcacg ggctcctggc ctggacagat gcgtacaatc tacggggatc acgagcggtt
    12541 tattcagact tacttttcag cgtacccagg ttattacact acaggtgatg gggcccgccg
    12601 cgatgacgac ggttattatt ggattaccgg tcgcgtggac gacgtgatca acgtatccgg
    12661 gcaccgcatg ggaaccgccg aggtagaaag tgccctggtt tcgcatgagc aggtcgcaga
    12721 agctgcggtt gtcggatacc cccatgaaat caagggacaa gggatttacg cgtacgtcac
    12781 tcctatggcc ggtgtgacgc cgagcgagga gcttcgccgg gggctcatag cccaggtacg
    12841 caaggagatc ggccctattg caagcccgga tatcatccaa tgggcgccgg gcctacctaa
    12901 aacccgatcg ggaaagatca tgcgccgtat cctgcgcaaa atagccgcga atgagctgga
    12961 aaatcttggt gatacatcca ctctggcaga gccagcggtg gtagatgaat tgatcaagaa
    13021 tcgggtaaat taggtcgttc ggcccggatc cgagtctaat ccggcttgcc tgataaccct
    13081 ttggcggcta gaattgcgcg ccttaagcgc taaaaaagcg cgctccttgc ctcaccgcga
    13141 aatattggga ggctccaact cgaagggaga atactcatgc gacactacga agtcgtgttc
    13201 cttgtgcatc cagatcagag cgagcaggtg cccgcgatgg tcgaaaaata tcgcggcctc
    13261 atcgaaggca acggtggcca gattcatcgt tgtgaggact ggggccggcg tccacttgct
    13321 tataccatcg gtaaagtgca taaggctcac tatgttttga tgaacgttga aatagatcag
    13381 ccaacgatgg atgaaatggc gaatatgttc aagttcagcg atgccgtcat ccgtaacctt
    13441 gtgatccgtc gaaaagaggc tgttactgag gcctcggcac tggtagttga ggctggagca
    13501 ggcgcagttg acagtgaaca aaagcctgct gaggtcgccc cggaaaccc
//
