LOCUS       c00272_3300028..        5207 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300028400.a:Ga0256832_1013617.
ACCESSION   c00272_3300028..
VERSION     c00272_3300028..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:57:56
            Original ID  :: 3300028400.a:Ga0256832_1013617
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5207
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5207
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[459:5207]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      460..5207
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..5207
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5207
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             2..421
                     /NRPS_PKS="Domain: PCP (35-104). E-value: 7.2e-29. Score:
                     91.6. Matches aSDomain: nrpspksdomains_ctg272_1_PCP.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg272_1"
                     /sec_met_domain="PP-binding (E-value: 4.6e-20, bitscore:
                     59.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="WQYGRAAEEENDAEERTLYDRPNLPTPYVAPRNDLEKEIATVWQQ
                     LLGIGQVGIHDDFFDLGGNSLMGTQLISRMRERFKVDVPVKSLFENPTIAGVAVQIEQA
                     RSTTEKQEDMLSDMLSKVENMSEEEIKAMLKRNDS"
     aSDomain        107..313
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg272_1_PCP.1"
                     /evalue="7.20E-29"
                     /label="ctg272_1_PCP.1"
                     /locus_tag="ctg272_1"
                     /protein_end="104"
                     /protein_start="35"
                     /score="91.6"
                     /tool="antismash"
                     /translation="EKEIATVWQQLLGIGQVGIHDDFFDLGGNSLMGTQLISRMRERFK
                     VDVPVKSLFENPTIAGVAVQIEQAR"
     aSModule        107..313
                     /domains="nrpspksdomains_ctg272_1_PCP.1"
                     /incomplete
                     /locus_tags="ctg272_1"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       170..199
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_1_0001"
                     /evalue="2.90E-03"
                     /label="PCP_mC"
                     /locus_tag="ctg272_1"
                     /protein_end="66"
                     /protein_start="56"
                     /score="11.0"
                     /tool="antismash"
                     /translation="DFFDLGGNSLM"
     CDS             460..3813
                     /NRPS_PKS="Domain: Condensation_LCL (41-336). E-value:
                     8.2e-117. Score: 381.2. Matches aSDomain:
                     nrpspksdomains_ctg272_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (503-906). E-value: 1.2e-97.
                     Score: 318.8. Matches aSDomain:
                     nrpspksdomains_ctg272_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1016-1084). E-value: 1.5e-24.
                     Score: 77.7. Matches aSDomain:
                     nrpspksdomains_ctg272_2_PCP.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     353.5; E-value: 2.7e-107)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg272_2"
                     /sec_met_domain="Condensation (E-value: 2.5e-79, bitscore:
                     254.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.3e-113, bitscore:
                     365.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.4e-17, bitscore:
                     49.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIYDQIAKLPPEKRAVLEMMLQEQGVDLSQMPILPRSGDEESFP
                     LSFAQQRLWFLDQLEPGSPLYNICSPVRITGELNVEALRRAFELIVNKHEVLRTTFFKE
                     GAEARQKVHSDFKLDFEIIDHGATGDIHEAIKAEAGHSFNLRDKAPIRVRLFRQHDKEH
                     VLVLTLHHIVSDNWSTGVLIKEFMELYPPLAAGKTVDFTPLTIQYADFAAWQRKWLSGK
                     TLQKQLDYWTEKLDGLPPVLDLPTDFPRPAYQSHNGDYITFQLDTENTAALKKLADAHD
                     VTLFMALMAAFEILMLRYSGQDDFAVGTPIANRNRAETEPLIGFFINTLVIRADVRDNP
                     SVATLLKRVKETMIGAYGHQDLPFETLVEKLDPERSMSHSPLFQTMLVFNNAPVGALKL
                     PGVELELLEFENKTTKFDLIFNFTEQNERLDGKVEYNTDLFKGETVKRMIRHFERIVRE
                     MSREAAREIELLPLLSSAEQEQALHRSKKNSRRVRATELLIPSILAQCELRGEKTALRA
                     GNTSMSYAGLRKRIYSLRKQLRDKHIQPGQVVAVLARRSPHTVAAMLAVMGHGAVYLPI
                     DPSYPRERLQFMLEDSGAVTLMVEEELASLGKELFSGERLTVMDTNDQAAAAEPGDAPE
                     EEAPAYLIYTSGSTGKPKGVLVSHRAMADHTVDMTQYFTLSADDVTLQFAAMNFDASLE
                     QILSPLLAGATIVMRDEDIWPVERFAEKINEYGLTVVNPTTAYWNLWCAYLQKNEKEIT
                     CPTLRLVISGGDAMSPAALKQWWASPFRQVRLINAYGPTETVITATCYDVPADETVLER
                     YHSIPIGTANANRELYVLDNHRNLLPPGLPGELCIAGDNLALGYLNRPEEESAAFVPHP
                     FAEKGRMYRTGDKVRLHDDGNLEFMGRVDQQVKIRGFRIEPGEVENILAAHPDLDTALV
                     AVKRDGHGEKQLVGYFRPHAGSRPEISALRDFLQKQLPPYMVPAAFIELDTIPMLPGGK
                     VNRRALPVPEDLRSQLSAEYVAPRTETEEELAAIVASVLRIEKVGVYDNFFELGGHSML
                     GTQVMSLIQEKFAVEVPLRVLFENPTVDGIAAAITEALTESLDEEELADLLGDVTDLSD
                     DDLNALLNED"
     aSDomain        583..1467
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg272_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="8.20E-117"
                     /label="ctg272_2_Condensation_LCL.1"
                     /locus_tag="ctg272_2"
                     /protein_end="336"
                     /protein_start="41"
                     /score="381.2"
                     /tool="antismash"
                     /translation="ESFPLSFAQQRLWFLDQLEPGSPLYNICSPVRITGELNVEALRRA
                     FELIVNKHEVLRTTFFKEGAEARQKVHSDFKLDFEIIDHGATGDIHEAIKAEAGHSFNL
                     RDKAPIRVRLFRQHDKEHVLVLTLHHIVSDNWSTGVLIKEFMELYPPLAAGKTVDFTPL
                     TIQYADFAAWQRKWLSGKTLQKQLDYWTEKLDGLPPVLDLPTDFPRPAYQSHNGDYITF
                     QLDTENTAALKKLADAHDVTLFMALMAAFEILMLRYSGQDDFAVGTPIANRNRAETEPL
                     IGFFINTLVIRADVR"
     aSModule        583..3711
                     /complete
                     /domains="nrpspksdomains_ctg272_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg272_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg272_2_PCP.1"
                     /locus_tags="ctg272_2"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       598..630
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_2_0001"
                     /evalue="1.80E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg272_2"
                     /protein_end="57"
                     /protein_start="46"
                     /score="10.8"
                     /tool="antismash"
                     /translation="SFAQQRLWFLDQ"
     CDS_motif       649..762
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_2_0002"
                     /evalue="7.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg272_2"
                     /protein_end="101"
                     /protein_start="63"
                     /score="57.0"
                     /tool="antismash"
                     /translation="PLYNICSPVRITGELNVEALRRAFELIVNKHEVLRTTFF"
     CDS_motif       964..1029
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_2_0003"
                     /evalue="3.80E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg272_2"
                     /protein_end="190"
                     /protein_start="168"
                     /score="32.2"
                     /tool="antismash"
                     /translation="LHHIVSDNWSTGVLIKEFMELYP"
     CDS_motif       1078..1116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_2_0004"
                     /evalue="1.70E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg272_2"
                     /protein_end="219"
                     /protein_start="206"
                     /score="20.3"
                     /tool="antismash"
                     /translation="QYADFAAWQRKWLS"
     CDS_motif       1369..1458
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_2_0005"
                     /evalue="2.30E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg272_2"
                     /protein_end="333"
                     /protein_start="303"
                     /score="55.3"
                     /tool="antismash"
                     /translation="DFAVGTPIANRNRAETEPLIGFFINTLVIRA"
     CDS_motif       1507..1626
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_2_0006"
                     /evalue="4.20E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg272_2"
                     /protein_end="389"
                     /protein_start="349"
                     /score="70.6"
                     /tool="antismash"
                     /translation="KETMIGAYGHQDLPFETLVEKLDPERSMSHSPLFQTMLVFN"
     aSDomain        1969..3177
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg272_2_AMP-binding.1"
                     /evalue="1.20E-97"
                     /label="ctg272_2_AMP-binding.1"
                     /locus_tag="ctg272_2"
                     /protein_end="906"
                     /protein_start="503"
                     /score="318.8"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="AQCELRGEKTALRAGNTSMSYAGLRKRIYSLRKQLRDKHIQPGQV
                     VAVLARRSPHTVAAMLAVMGHGAVYLPIDPSYPRERLQFMLEDSGAVTLMVEEELASLG
                     KELFSGERLTVMDTNDQAAAAEPGDAPEEEAPAYLIYTSGSTGKPKGVLVSHRAMADHT
                     VDMTQYFTLSADDVTLQFAAMNFDASLEQILSPLLAGATIVMRDEDIWPVERFAEKINE
                     YGLTVVNPTTAYWNLWCAYLQKNEKEITCPTLRLVISGGDAMSPAALKQWWASPFRQVR
                     LINAYGPTETVITATCYDVPADETVLERYHSIPIGTANANRELYVLDNHRNLLPPGLPG
                     ELCIAGDNLALGYLNRPEEESAAFVPHPFAEKGRMYRTGDKVRLHDDGNLEFMGRVDQQ
                     VKIRG"
     CDS_motif       2377..2436
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_2_0007"
                     /evalue="1.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg272_2"
                     /protein_end="659"
                     /protein_start="639"
                     /score="33.2"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGKPKGVLVSHR"
     CDS_motif       2971..3060
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_2_0008"
                     /evalue="1.00E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg272_2"
                     /protein_end="867"
                     /protein_start="837"
                     /score="40.3"
                     /tool="antismash"
                     /translation="PPGLPGELCIAGDNLALGYLNRPEEESAAFV"
     CDS_motif       3142..3207
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_2_0009"
                     /evalue="4.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg272_2"
                     /protein_end="916"
                     /protein_start="894"
                     /score="37.8"
                     /tool="antismash"
                     /translation="FMGRVDQQVKIRGFRIEPGEVEN"
     aSDomain        3508..3711
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg272_2_PCP.1"
                     /evalue="1.50E-24"
                     /label="ctg272_2_PCP.1"
                     /locus_tag="ctg272_2"
                     /protein_end="1084"
                     /protein_start="1016"
                     /score="77.7"
                     /tool="antismash"
                     /translation="EEELAAIVASVLRIEKVGVYDNFFELGGHSMLGTQVMSLIQEKFA
                     VEVPLRVLFENPTVDGIAAAITEA"
     CDS             3837..5207
                     /NRPS_PKS="Domain: Condensation_LCL (45-339). E-value:
                     2e-110. Score: 360.2. Matches aSDomain:
                     nrpspksdomains_ctg272_3_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     402; E-value: 6.3e-122)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg272_3"
                     /sec_met_domain="Condensation (E-value: 1.5e-75, bitscore:
                     241.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLSKKLQNLSPEQRELLLKKLQARKKKSTAESRPETIQPRPDR
                     ESYPLSYAQERLWFFDQLVPGSPLYNISAAVKFYGPLNAAHLEKSINAVVERHEVLQVF
                     FRTEKGAPVQHKAEGLFIPLTMENKDARSLEEIAAAEAQTPFDLTRAPLIRTRLIRLDD
                     QTHVLMLTIHHIVADGWSMGVFINETARFYRRFNGDTSVTLEALPIQYFDYAWWQKNAA
                     DEKKLRKQLNFWSSELKGMPTLLELPFDHKREAVQSFKGSHHHFSIDAATTKRLHELSR
                     QAGTTLFITLLAAFQTLLYRYSHQDDFGVGIPIANRNKKELETLIGFFVNTLVIRARCQ
                     GDISFLDFLSRVKKRAFQAYDHQDVPFEQVVEKVQPQRNNQVSPLFQVMFELQGDALAG
                     LNFGDLTLENIDFETGTAKFDLLLIMEDRRDSLHGVIEYNSALFEPETIERMMHHFTH"
     aSDomain        3972..4853
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg272_3_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.00E-110"
                     /label="ctg272_3_Condensation_LCL.1"
                     /locus_tag="ctg272_3"
                     /protein_end="339"
                     /protein_start="45"
                     /score="360.2"
                     /tool="antismash"
                     /translation="ESYPLSYAQERLWFFDQLVPGSPLYNISAAVKFYGPLNAAHLEKS
                     INAVVERHEVLQVFFRTEKGAPVQHKAEGLFIPLTMENKDARSLEEIAAAEAQTPFDLT
                     RAPLIRTRLIRLDDQTHVLMLTIHHIVADGWSMGVFINETARFYRRFNGDTSVTLEALP
                     IQYFDYAWWQKNAADEKKLRKQLNFWSSELKGMPTLLELPFDHKREAVQSFKGSHHHFS
                     IDAATTKRLHELSRQAGTTLFITLLAAFQTLLYRYSHQDDFGVGIPIANRNKKELETLI
                     GFFVNTLVIRARCQ"
     aSModule        3972..4853
                     /domains="nrpspksdomains_ctg272_3_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg272_3"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3987..4016
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_3_0001"
                     /evalue="3.20E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg272_3"
                     /protein_end="60"
                     /protein_start="50"
                     /score="10.1"
                     /tool="antismash"
                     /translation="SYAQERLWFFD"
     CDS_motif       4038..4139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_3_0002"
                     /evalue="1.60E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg272_3"
                     /protein_end="101"
                     /protein_start="67"
                     /score="43.0"
                     /tool="antismash"
                     /translation="PLYNISAAVKFYGPLNAAHLEKSINAVVERHEVLQ"
     CDS_motif       4350..4415
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_3_0003"
                     /evalue="4.20E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg272_3"
                     /protein_end="193"
                     /protein_start="171"
                     /score="38.4"
                     /tool="antismash"
                     /translation="IHHIVADGWSMGVFINETARFYR"
     CDS_motif       4464..4496
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_3_0004"
                     /evalue="3.20E-02"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg272_3"
                     /protein_end="220"
                     /protein_start="209"
                     /score="7.3"
                     /tool="antismash"
                     /translation="QYFDYAWWQKNA"
     CDS_motif       4755..4844
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_3_0005"
                     /evalue="1.90E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg272_3"
                     /protein_end="336"
                     /protein_start="306"
                     /score="45.9"
                     /tool="antismash"
                     /translation="DFGVGIPIANRNKKELETLIGFFVNTLVIRA"
     CDS_motif       4896..5009
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg272_3_0006"
                     /evalue="3.50E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg272_3"
                     /protein_end="391"
                     /protein_start="353"
                     /score="67.6"
                     /tool="antismash"
                     /translation="KRAFQAYDHQDVPFEQVVEKVQPQRNNQVSPLFQVMFEL"
ORIGIN
        1 gtggcagtac ggccgggccg cggaggagga aaatgacgcg gaagagcgta ccctgtatga
       61 ccgccccaac ctgcccaccc cctatgtcgc gccgcgcaac gatctggaaa aagagatcgc
      121 cacggtctgg caacagcttt taggtatcgg acaggtgggc attcatgacg actttttcga
      181 cctggggggc aactcactga tgggcaccca gcttatatca cgcatgcgtg aacgctttaa
      241 agtggatgta ccggttaaaa gcctttttga gaatccgacc atcgccggtg tggccgtgca
      301 gattgaacag gcccgttcta ccacggagaa gcaggaagat atgttaagcg acatgctgag
      361 caaggtggaa aatatgagtg aggaagagat caaagccatg ctgaaaagga acgattctta
      421 attagcaacc gctggtttta aaggaaaaag aaaacacata tgtcgattta cgaccaaata
      481 gccaagctgc cccctgaaaa acgggcggtg ttagagatga tgcttcagga acagggggtg
      541 gatctttcac aaatgcccat actgccccgc agcggtgatg aggagagctt tcccctctcc
      601 tttgcccagc agcgtttatg gttcctggat cagctggaac cgggcagtcc gctttataat
      661 atttgttcgc cggtgcgcat taccggagag cttaatgttg aggccctgcg ccgggccttt
      721 gagctgatcg tgaacaagca tgaagtgctg cgcaccactt tttttaaaga gggcgccgaa
      781 gcccggcaaa aagttcatag tgactttaag ctggattttg aaattatcga tcacggcgcc
      841 accggagata ttcacgaggc catcaaggcg gaggccggcc attcctttaa cctgagggat
      901 aaggccccga tacgtgttcg actgtttcgc cagcatgaca aggaacatgt gctggtattg
      961 accctgcatc acattgtttc ggacaactgg tccaccggtg tgctgataaa agagtttatg
     1021 gagctctacc cgcccctggc cgcaggaaaa acggttgact ttaccccctt gaccatacag
     1081 tatgccgatt ttgccgcctg gcagcgtaaa tggctctccg ggaaaaccct gcaaaaacaa
     1141 ctggattact ggacggaaaa gctggacggt ctgccaccgg tgcttgacct gcccacggac
     1201 tttccccggc cggcctatca aagccataac ggggactaca ttacctttca gcttgatacc
     1261 gaaaacacgg cagccttaaa aaagctggcc gacgcccatg acgtcaccct gttcatggcc
     1321 ttaatggccg cttttgagat tctgatgcta cgttatagcg gccaggatga ttttgccgtc
     1381 ggcaccccca tcgccaaccg caaccgcgcc gaaactgagc cactgatcgg tttttttatc
     1441 aacaccctgg tcatccgtgc cgatgtgcgc gacaatccca gcgtggccac tttgttaaaa
     1501 cgggtaaagg agaccatgat cggcgcttac ggtcatcagg atttgccctt tgaaaccctg
     1561 gtggagaaac tcgatcccga aagaagcatg agccactctc ccctgttcca gaccatgctg
     1621 gtgtttaaca atgcccccgt gggcgccctg aaattgcccg gcgttgaact ggaactgctt
     1681 gagtttgaaa acaaaaccac aaaatttgat ctcattttta attttacgga acagaatgaa
     1741 cgcctcgatg gcaaggtgga gtacaacacc gatctgttta agggcgaaac cgttaaacgc
     1801 atgatccgcc actttgaacg catcgtgcgg gagatgagcc gggaggccgc ccgggaaatc
     1861 gaactgctgc ccctgctaag ctccgcggaa caagaacaag cgttgcaccg gagtaagaaa
     1921 aacagcagac gggtacgggc cacggaactt ctcatccctt ccatactggc acaatgtgaa
     1981 ctacggggcg aaaaaacggc cctgcgtgcc ggcaacactt cgatgagcta tgccgggctg
     2041 agaaaacgga tttatagtct gaggaagcaa ctgcgggata aacatatcca acccggtcag
     2101 gtagtggccg tgctggcccg gcgctcacca cacaccgtgg ccgccatgct ggcggttatg
     2161 ggacacggcg ccgtctattt acccatagac ccgtcctacc cgcgggagcg tttacaattt
     2221 atgctggaag acagcggagc cgtcaccctg atggtggaag aagaactggc ctctttggga
     2281 aaggaattgt tttccggcga gcgcttaacg gtaatggata caaatgatca ggctgccgcg
     2341 gcagagcccg gggacgcgcc ggaggaagag gcccccgcct atctgattta tacctccggc
     2401 tccacgggga aacccaaggg cgtgctcgtc agtcatcgcg ccatggccga ccataccgtg
     2461 gacatgacgc aatactttac cctgagcgcg gatgatgtga ccctgcaatt cgcggccatg
     2521 aactttgacg cttccctgga gcagatatta tcccccctgc tggccggggc caccatcgtt
     2581 atgcgtgatg aggatatctg gcccgtggaa cgcttcgccg aaaagattaa cgaatacggc
     2641 ctgaccgtgg tcaatcccac taccgcttat tggaacctgt ggtgtgccta tctgcaaaaa
     2701 aacgaaaagg aaatcacctg tcccaccctg cgtctggtaa tttccggtgg cgatgccatg
     2761 agccccgccg ccttaaaaca gtggtgggcc tcgcctttcc ggcaggtaag actgatcaat
     2821 gcctacgggc ccacggagac ggtcattacc gccacctgtt atgacgtgcc cgccgatgag
     2881 actgtcctgg aacgctatca cagtatcccc atcggcacgg ccaacgccaa ccgcgagctt
     2941 tatgtgttgg ataaccaccg caacctgctg cccccgggtc tgcccggcga actgtgcatt
     3001 gccggcgaca atctggccct gggttatctg aaccgtccgg aggaggaaag cgccgctttt
     3061 gtcccccatc cgtttgcgga gaaggggcgg atgtatcgca cgggagacaa ggtgcgcctg
     3121 catgatgacg ggaatctgga atttatgggc cgcgtggatc agcaggtaaa aattcgcggc
     3181 ttccgaatcg aacccggcga ggtggaaaac atcctggccg cgcatcccga tctggatacg
     3241 gccctggtgg cggttaaaag ggatggtcat ggcgaaaaac aactggtggg ctatttccgc
     3301 ccccatgccg gtagccggcc ggagatcagc gcattaagag acttcctgca aaaacaactg
     3361 ccgccttaca tggtacccgc ggcttttatc gagttggaca ccatccccat gcttcccggc
     3421 ggcaaggtca accgccgcgc cctgccggtt cccgaagacc tgcgcagcca gctcagcgcc
     3481 gaatatgtgg cgccgcgcac cgaaacggaa gaagaactgg ccgccatcgt cgcctcggtg
     3541 ttgcgcattg agaaagtggg ggtttatgac aattttttcg aactgggagg ccactccatg
     3601 ctgggaacac aggtaatgtc cctgatacag gaaaaattcg cggtggaagt ccccctgcgt
     3661 gtgctgtttg agaaccccac cgtggacggt atcgccgccg ccataaccga ggcgctgacc
     3721 gaatccctgg atgaagagga actggccgat ttactgggag acgtcaccga cttatccgat
     3781 gacgatctca acgccctatt aaatgaagat tagaacgaca ggaattaaca acctttatga
     3841 gcgatctttc caaaaagctg caaaacctaa gccctgaaca gcgcgaactt ctcctgaaaa
     3901 aattacaggc ccgcaaaaaa aagagtacgg cagaaagccg cccggaaacc atacaacccc
     3961 ggccggacag ggagagctat cccctctcct atgcccagga gcgtttatgg ttttttgacc
     4021 agcttgtccc cggaagcccg ctgtacaaca tcagcgcggc ggttaagttt tacggcccct
     4081 taaacgcggc ccatctggaa aaaagcatca atgccgttgt cgagcgtcat gaggttttgc
     4141 aggttttctt ccgcaccgaa aaaggggcgc ctgttcagca taaggcggag gggcttttta
     4201 tccccctgac catggaaaat aaggatgccc gttccctgga agagatcgcc gccgccgagg
     4261 cccagactcc ttttgaccta acccgggccc cgcttatccg tacccggctg atccgtctgg
     4321 acgaccagac acatgttttg atgctgacca tccaccacat tgtggccgat ggctggtcca
     4381 tgggcgtttt catcaatgag acggcccgct tttaccgccg tttcaacgga gatacctccg
     4441 tcacgctcga ggccctgccc atccagtatt ttgattatgc ctggtggcaa aaaaatgccg
     4501 ccgatgaaaa aaagctgcgt aaacaactca atttctggtc ttccgaactg aaaggcatgc
     4561 ccacactgct ggaattgccc ttcgaccata agcgtgaggc cgtgcaaagt tttaagggaa
     4621 gtcatcatca cttttccatt gacgcggcca ccacaaaaag actgcatgaa ttatcccggc
     4681 aggcgggtac caccttattc attaccctgc tggccgcctt ccagaccctg ctgtaccgct
     4741 attcccatca ggatgacttc ggcgtgggca tccccattgc caaccgcaat aaaaaagagc
     4801 tggaaaccct gatcggattt tttgtcaaca ctctggtgat ccgcgcccgc tgtcagggag
     4861 atatctcttt tcttgatttt ctctcccggg ttaaaaaacg ggccttccag gcctatgacc
     4921 atcaggatgt gccgtttgaa caggtggtgg agaaggtaca gccccaacgg aacaaccagg
     4981 tttcccctct tttccaggtg atgtttgaac ttcagggcga cgccctggcc gggctcaatt
     5041 tcggcgatct gaccctggaa aacatagatt ttgaaacggg cacggcaaaa tttgatctgc
     5101 tgttgatcat ggaagaccgc cgtgacagcc tccatggtgt catcgaatac aacagcgccc
     5161 tgtttgaacc ggaaacgatc gaacgcatga tgcaccattt cacccat
//
