LOCUS       c00251_3300028..        3744 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300028622.a:Ga0302253_1007212.
ACCESSION   c00251_3300028..
VERSION     c00251_3300028..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 05:08:53
            Original ID  :: 3300028622.a:Ga0302253_1007212
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3744
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3744
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3742](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2..3742)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3744
                     /SMILES="NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3744
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(2..3742)
                     /NRPS_PKS="Domain: AMP-binding (19-284). E-value: 1.1e-71.
                     Score: 233.3. Matches aSDomain:
                     nrpspksdomains_ctg251_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (390-456). E-value: 1.3e-22. Score:
                     71.5. Matches aSDomain: nrpspksdomains_ctg251_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (471-753). E-value:
                     5.5e-88. Score: 287.2. Matches aSDomain:
                     nrpspksdomains_ctg251_1_Epimerization.1"
                     /NRPS_PKS="Domain: PP-binding (1146-1212). E-value:
                     3.2e-07. Score: 22.6. Matches aSDomain:
                     nrpspksdomains_ctg251_1_PP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 261;
                     E-value: 2.8e-79)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg251_1"
                     /sec_met_domain="Condensation (E-value: 2.1e-65, bitscore:
                     206.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-91, bitscore:
                     291.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-16, bitscore:
                     47.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSIDEYRDELEKAPCSNPGRVSGSRDLAYVIYTSGSTGNPKGVMI
                     EQYGVVNLAFSHRKSLEITGDSRILHFAPLSFDASVSTLFCALLNGATLCMCTDEMRND
                     AAELSAFIAGSKISHIDIPAKLLEILPKDLDCTSLRSVITAGEICDSRTMEYWGGRVKL
                     INAYGPTESTVCATFAAYAPGRSNVNIGKPISNKKVYVLGSNLSPVPAGVPGELYIGGD
                     GLARCYLNQPDMTAARFVKNPFLHESDQTAERRMYRTGDVARWTRDGDLEFLGRNDDQV
                     KIRGYRIELAEVEHKLSACPGIAMCAVTACQQDLGRHLCAYYTVSGKTSADEIRAYLAT
                     ELPDYMIPSFYMELETFPLSASGKVDRKALPEPRAEAGGSSYVPPADELQQKICEIFSG
                     LLGVEKIGINDDFFRLGGDSIMSIQLSSSLRNAGLDCAVKDIFKNPTVLKLSEHIAAHR
                     EQKVPVIAEQGVLEGEFDLLPIQRWFFEHVTSGQFNARNHWNQSFMVKVPELDTDLLAR
                     CIQSLAMHHDMLRAVFTSDRQQYRREIAVPELKILDRSGLADDGLQDTLTGWQSGFDIE
                     RGPLWQIGYVRGFQDGSARLFFALHHLIADAVSWRILIEDMRRLYEGEQLKEKTSSYRQ
                     WVNAVKHYPEQHPDERHYWEAALRALPDYSPHSEEGAKPVKRELRLGRELTGQLIREAN
                     RAYLTQVNDLLLTAFAFALKDWHGGDTQGVTVEGHGREDIDPAIDHSHTLGWFTTVCPV
                     KLNVPDDPGRAIVSIKQALRQIPRRGIGWGAFCCSSHREGPGSLCNNLRLPPVTFNYLG
                     QLDSGEAGRLWQFVNEPSGVSIDPSNPDLSLIAVNGIAADGEMIFSVVTRLDEEATDRL
                     VLRFEESLLQIASHCLEVSRKGGLPGYNVEDFEYIPAALLNKNGRSKRLAIIIHPDSGY
                     EAYMATLYPALSSDIRVILVDNFYKKVYLRDGVVMEKYHFIEFSGLADYYVKLLLDGHG
                     ELIRESECCLIGYSFGSPIAIEMDRLFRERGIPMSSLYLIDPLIPHLLRTRRELDCFEW
                     YRDYVPARTATPVVHFRCTEPDPELPGYTEYFVNPRESSLSPIAENLEEINIRCRHTAI
                     LTEPGFLKAFGERANRDLILPSGERQVSEEIADLSVESSIRDIVRKAVELDDRAAIDGG
                     ANLFQLGCTSIQCLSVLGMVNERFRLDLALSDMIGSFTVKGIAALVAKAEKAGRDEERW
                     KPVEFASSEQQADALYFFPGLI"
     aSDomain        complement(107..304)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg251_1_PP-binding.1"
                     /evalue="3.20E-07"
                     /label="ctg251_1_PP-binding.1"
                     /locus_tag="ctg251_1"
                     /protein_end="1212"
                     /protein_start="1146"
                     /score="22.6"
                     /tool="antismash"
                     /translation="IRDIVRKAVELDDRAAIDGGANLFQLGCTSIQCLSVLGMVNERFR
                     LDLALSDMIGSFTVKGIAALVA"
     aSModule        107..304
                     /domains="nrpspksdomains_ctg251_1_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg251_1"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(707..751)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg251_1_0009"
                     /evalue="2.10E-03"
                     /label="NRPS-te1"
                     /locus_tag="ctg251_1"
                     /protein_end="1012"
                     /protein_start="997"
                     /score="10.7"
                     /tool="antismash"
                     /translation="CLIGYSFGSPIAIEMD"
     CDS_motif       complement(1391..1441)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg251_1_0008"
                     /evalue="1.50E-04"
                     /label="NRPS-E6"
                     /locus_tag="ctg251_1"
                     /protein_end="784"
                     /protein_start="767"
                     /score="14.3"
                     /tool="antismash"
                     /translation="IKQALRQIPRRGIGWGAF"
     CDS_motif       complement(1478..1528)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg251_1_0007"
                     /evalue="3.80E-06"
                     /label="NRPS-E5"
                     /locus_tag="ctg251_1"
                     /protein_end="755"
                     /protein_start="738"
                     /score="19.3"
                     /tool="antismash"
                     /translation="DHSHTLGWFTTVCPVKLN"
     aSDomain        complement(1484..2329)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg251_1_Epimerization.1"
                     /evalue="5.50E-88"
                     /label="ctg251_1_Epimerization.1"
                     /locus_tag="ctg251_1"
                     /protein_end="753"
                     /protein_start="471"
                     /score="287.2"
                     /tool="antismash"
                     /translation="EGEFDLLPIQRWFFEHVTSGQFNARNHWNQSFMVKVPELDTDLLA
                     RCIQSLAMHHDMLRAVFTSDRQQYRREIAVPELKILDRSGLADDGLQDTLTGWQSGFDI
                     ERGPLWQIGYVRGFQDGSARLFFALHHLIADAVSWRILIEDMRRLYEGEQLKEKTSSYR
                     QWVNAVKHYPEQHPDERHYWEAALRALPDYSPHSEEGAKPVKRELRLGRELTGQLIREA
                     NRAYLTQVNDLLLTAFAFALKDWHGGDTQGVTVEGHGREDIDPAIDHSHTLGWFTTVCP
                     VK"
     aSModule        1484..3685
                     /complete
                     /domains="nrpspksdomains_ctg251_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg251_1_PCP.1"
                     /domains="nrpspksdomains_ctg251_1_Epimerization.1"
                     /locus_tags="ctg251_1"
                     /monomer_pairings="tyr -> D-tyr"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1892..1957)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg251_1_0006"
                     /evalue="1.30E-09"
                     /label="NRPS-E2"
                     /locus_tag="ctg251_1"
                     /protein_end="617"
                     /protein_start="595"
                     /score="30.3"
                     /tool="antismash"
                     /translation="LFFALHHLIADAVSWRILIEDMR"
     CDS_motif       complement(2126..2170)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg251_1_0005"
                     /evalue="3.40E-06"
                     /label="Cy2"
                     /locus_tag="ctg251_1"
                     /protein_end="539"
                     /protein_start="524"
                     /score="19.5"
                     /tool="antismash"
                     /translation="HHDMLRAVFTSDRQQY"
     CDS_motif       complement(2285..2314)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg251_1_0004"
                     /evalue="3.80E-04"
                     /label="NRPS-E1"
                     /locus_tag="ctg251_1"
                     /protein_end="486"
                     /protein_start="476"
                     /score="13.4"
                     /tool="antismash"
                     /translation="LLPIQRWFFEH"
     aSDomain        complement(2375..2572)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg251_1_PCP.1"
                     /evalue="1.30E-22"
                     /label="ctg251_1_PCP.1"
                     /locus_tag="ctg251_1"
                     /protein_end="456"
                     /protein_start="390"
                     /score="71.5"
                     /tool="antismash"
                     /translation="QKICEIFSGLLGVEKIGINDDFFRLGGDSIMSIQLSSSLRNAGLD
                     CAVKDIFKNPTVLKLSEHIAAH"
     CDS_motif       complement(2861..2926)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg251_1_0003"
                     /evalue="2.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg251_1"
                     /protein_end="294"
                     /protein_start="272"
                     /score="38.6"
                     /tool="antismash"
                     /translation="FLGRNDDQVKIRGYRIELAEVEH"
     aSDomain        complement(2891..3685)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg251_1_AMP-binding.1"
                     /evalue="1.10E-71"
                     /label="ctg251_1_AMP-binding.1"
                     /locus_tag="ctg251_1"
                     /protein_end="284"
                     /protein_start="19"
                     /score="233.3"
                     /specificity="consensus: tyr"
                     /tool="antismash"
                     /translation="RVSGSRDLAYVIYTSGSTGNPKGVMIEQYGVVNLAFSHRKSLEIT
                     GDSRILHFAPLSFDASVSTLFCALLNGATLCMCTDEMRNDAAELSAFIAGSKISHIDIP
                     AKLLEILPKDLDCTSLRSVITAGEICDSRTMEYWGGRVKLINAYGPTESTVCATFAAYA
                     PGRSNVNIGKPISNKKVYVLGSNLSPVPAGVPGELYIGGDGLARCYLNQPDMTAARFVK
                     NPFLHESDQTAERRMYRTGDVARWTRDGDLEFLGRNDDQVKIRG"
     CDS_motif       complement(3026..3115)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg251_1_0002"
                     /evalue="3.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg251_1"
                     /protein_end="239"
                     /protein_start="209"
                     /score="54.5"
                     /tool="antismash"
                     /translation="PAGVPGELYIGGDGLARCYLNQPDMTAARFV"
     CDS_motif       complement(3605..3661)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg251_1_0001"
                     /evalue="2.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg251_1"
                     /protein_end="46"
                     /protein_start="27"
                     /score="32.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGNPKGVMIEQ"
ORIGIN
        1 cgatgagacc tgggaagaag tacagcgcgt cggcctgctg ttccgaagag gcgaactcca
       61 caggcttcca gcgctcttca tcgcgcccgg ccttctccgc cttcgcaacc agcgccgcaa
      121 tgcccttgac ggtgaagctc cctatcatat cgctgagggc caggtcgagc ctgaagcgct
      181 cattgaccat gccgagcact gacaggcact ggattgacgt gcagcccagc tggaacagat
      241 ttgcgccgcc gtcgatggca gccctgtcgt ccaactctac cgccttcctg acaatatccc
      301 tgatcgagct ctcaacagac aggtctgcta tttcttcact cacctgcctc tcgccggaag
      361 gcaggatcag atccctgtta gccctctcgc cgaaggcctt cagaaagcca ggttcggtca
      421 ggatggctgt atggcggcac ctgatgttta tctcctcgag gttttctgca atcggagaca
      481 gcgatgactc cctgggattg acaaagtatt cagtgtagcc gggaagctca gggtccggct
      541 ctgtgcatct gaaatggacc accggtgttg ccgtgcgggc cgggacgtaa tccctgtacc
      601 attcgaagca gtcgagctct ctgcgtgtcc tgaggagatg cggtatcagg gggtcgatta
      661 gatagaggga gctcatcggt atgccgcgct ctctgaacaa cctgtccatc tcgatcgcta
      721 tcgggctgcc aaagctgtaa ccgatcagac agcactcaga ttccctgatc agctctccgt
      781 gcccgtcgag gagaagcttt acgtagtaat ctgcaagccc gctgaactcg atgaaatgat
      841 atttctccat taccacgcca tcccgtagat agaccttctt gtagaagttg tccacgagga
      901 tgactcttat atcgctcgag agggccgggt acagcgtggc catgtaggct tcgtagcctg
      961 aatcgggatg gatgatgatg gcaagcctct tcgagcggcc gtttttattc agcagcgcgg
     1021 ctggaatgta ctcgaaatcc tccacgttgt atcccggaag gccgcctttc ctgctgacct
     1081 ccaggcagtg cgaagcgatc tgcagcagcg actcctcgaa tctcaggacc agcctgtcgg
     1141 tggcctcttc atcgagtctc gtcaccacgc tgaaaatcat ctccccgtct gcggctatcc
     1201 cattgacggc gatcaggctc agatcggggt tggaagggtc aatgctcacg cctgacggct
     1261 cgttcacgaa ctgccagagc ctgcctgcct cgccgctgtc aagctgcccg aggtagttga
     1321 aagtcacggg agggaggcgg aggttattgc acaggctgcc tgggccttcc cggtgggagg
     1381 agcagcagaa ggctccccag ccgatacccc tgcgggggat ctgcctcagc gcctgcttga
     1441 tgctcacgat ggccctgccg ggatcgtccg gcacgttgag cttgacagga cagactgttg
     1501 tgaaccaacc cagagtgtgg ctgtggtcta tggccggatc gatatcctct ctgccgtggc
     1561 cttccacggt gacgccctga gtatcgccgc cgtgccagtc cttcagggca aaggcaaaag
     1621 ccgtgagaag caggtcgttt acctgtgtca aataagccct gttggcctcc ctgatcagct
     1681 ggccggtcaa ctctctgccg aggcgcagct ccctcttgac aggcttggcg ccttcttcgc
     1741 tgtgggggct gtaatccggg agcgcccgta atgcagcctc ccagtaatgt ctctcatcgg
     1801 ggtgctgttc aggataatgc tttacggcat tgacccactg gcggtagctg ctcgtcttct
     1861 ccttcagctg ctctccctcg tacagtctcc tcatatcctc gatcagtatc ctccagctca
     1921 cggcatctgc aatcaggtga tgaagggcga agaacagcct cgcgctgccg tcctggaaac
     1981 ccctcacata gccgatctgc cacagtggcc cgcgctcgat atcgaacccg ctctgccatc
     2041 cggtcagggt atcctgcagc ccgtcatctg ccagcccgct tctgtccagt atcttcagct
     2101 cagggactgc aatctcgcgc cggtactgct gcctgtccga tgtaaatacc gcccggagca
     2161 tatcgtgatg catggcgaga gactggatgc accgcgccag aagatccgta tccagctcgg
     2221 gaaccttcac catgaagctc tggttccagt gattgcgagc attgaactgc ccgctcgtca
     2281 cgtgctcgaa gaaccaccgc tggatcggaa gcaggtcgaa ctcgccttcc agaacgccct
     2341 gctctgcgat gacagggact ttctgctccc ggtgcgcggc gatatgctct gagagcttca
     2401 gcacagtcgg gtttttgaag atgtccttca ctgcgcagtc cagcccggcg tttctgaggc
     2461 tcgacgagag ctggatgctc attatcgagt cgccgccgag cctgaagaaa tcgtcgttga
     2521 tccctatctt ttccacgccc agcaatccgc tgaagatttc gcagatcttc tgctgcaatt
     2581 catcggcggg aggcacgtaa gatgacccgc cggcttccgc tctcggctcc ggcagggctt
     2641 tgcggtccac cttccctgac gcggagagcg ggaatgtctc cagctccata tagaatgacg
     2701 ggatcatgta gtcaggcagc tcagtggcga ggtaagccct tatctcgtct gccgatgtct
     2761 tcccggagac tgtgtagtaa gcgcagagat gcctgccgag gtcttgctgg caggccgtga
     2821 cggcgcacat ggcgatgccc gggcaggctg acagtttgtg ctcgacctct gcaagctcta
     2881 tcctgtagcc gcggatcttc acctggtcat cgttgcggcc gaggaactcg agatcgccgt
     2941 ccctggtcca ccgggccacg tctcctgtcc tgtacatgcg ccgctcggca gtctggtcgc
     3001 tctcatgcag gaaggggttc ttcacgaacc tggcggctgt catgtccggc tggttcagat
     3061 agcatctcgc cagcccgtcg ccgccgatgt aaagctctcc cggcacgcct gccggaacgg
     3121 ggctgagatt gctgcccagc acgtacacct tcttgttgct gattggcttc cctatgttca
     3181 cgttgctccg gccaggcgca taggccgcaa aggtcgcgca gaccgtagat tcggttggcc
     3241 cgtacgcgtt aatcagcttg accctgccgc cccagtattc catggtcctg ctgtcgcata
     3301 tctctcctgc ggtgatgacg gagcgcaggc tcgtgcagtc cagatccttc ggcaggatct
     3361 ctaggagctt cgcagggatg tctatgtggc tgatcttcga gccggctatg aaagccgaca
     3421 gctctgcggc gtcgtttctc atctcgtcgg tgcacatgca cagcgtggct ccgttgagca
     3481 gcgcgcagaa gagagtggag accgaggcgt cgaagctgag aggggcgaaa tgaaggatcc
     3541 gcgagtctcc ggtgatttcg aggctctttc tgtgcgagaa ggccaggttg accacgccgt
     3601 actgctcgat catcactcct tttggattcc ctgtcgagcc tgaagtatag atgacgtagg
     3661 ccagatccct cgagccgctg acccggccgg gattcgagca gggcgccttt tcgagctcgt
     3721 ccctgtattc atcgatcgac aggg
//
