LOCUS       c00427_3300028..        3208 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300028622.a:Ga0302253_1008657.
ACCESSION   c00427_3300028..
VERSION     c00427_3300028..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 05:08:53
            Original ID  :: 3300028622.a:Ga0302253_1008657
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3208
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..3207
                     /NRPS_PKS="Domain: PCP (246-310). E-value: 3.6e-24. Score:
                     76.5. Matches aSDomain: nrpspksdomains_ctg427_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (324-630). E-value:
                     3.3e-145. Score: 476.5. Matches aSDomain:
                     nrpspksdomains_ctg427_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (636-788). E-value: 1.6e-46.
                     Score: 149.7. Matches aSDomain:
                     nrpspksdomains_ctg427_1_TIGR01720.1"
                     /NRPS_PKS="Domain: Condensation_DCL (795-1069). E-value:
                     3.5e-91. Score: 297.2. Matches aSDomain:
                     nrpspksdomains_ctg427_1_Condensation_DCL.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     249.4; E-value: 1.3e-75)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg427_1"
                     /sec_met_domain="Condensation (E-value: 6.2e-68, bitscore:
                     215.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 9.4e-52, bitscore:
                     162.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-16, bitscore:
                     47.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ALSWALQQKFFEVSGAELYNLYGPTEASVDVSFWRCDPDGPEGTV
                     PIGYPIANTSLHILDRNMNPVPEGFPGELFIGGAGLARGYIASPALTSERFIADPFTTG
                     GRLYRTGDRARRLPGGAIEFLGRLDSQVKIHGFRIEPGEIESALLSHSAIRDCAVVARE
                     DRPGIRRLVAYAVLKDSAESPGSIKTELDAIAGEKLPPYMKPSAYVILPALPLTASGKT
                     DRKALPVPEPAAGLDASAPPRTSAEKTIAGIWADVLDLDSVGAHDNFFALGGDSIISIQ
                     AVSRAREAGLSMTVRMLFEHPTVAQLALVCGGMPALEAEQGIVTGEAPLTPIQRWFFSS
                     EPAEPWHFNQSVLLEVPGRFEPALAVSALRAIISHHDALRLRFARTGGDWSQRIVGDGQ
                     SDTFTSVDLSNLEDCDFSTAVEAAASAAQAGLDISEGLLIRALHFSRGAESSGRLLLII
                     HHLAVDGVSWRILLSDLDRAYRQLLDGEEISLPAKSTSYPVWALRLEEYASSCRMAEEA
                     AYWNDEAARLADPIPCDLPGTPDSNTVGSSCTVSLELDEALTESLIRDIPPVYNTRIND
                     ALLTALGMALLRWTGRNVFTIDVEGHGREEIFDGMDVSRTVGWFTSLFPVTIEISGRAD
                     PGSDLKSVKERLRSIPDKGIGYGILRYLAADRQLLISGRSEAQVSFNYLGQVDSAFADG
                     EFRIAAESAGNDTSPAMVRRHLIDVTGIVSSGRLSLNITYSRHFHRRETAERLAEWLEE
                     SLRELVRHCMTPGAGGRTPSDFPLASLAQSDLDRLFAGHEQIEDLYPLTPMQQGLLFHA
                     LRSPDSDMYREQASCMLTGDLDSAAFQRAWQSVVDRHSVLRTYFIWEDMSEPLQAVKRR
                     ATLPWIEEDWRHLGAGELEKRRRELLGGSGRRALDLKSAPVANAHLARLDDRKWLFVWC
                     HHHTLMDGWSFPIVLREVFSLYRSYMDRTDSALPPPRPYRDYIEWMRAQDMGRSEAFWR
                     EELRGFTAPTLLASDRRAEEPGIGMELVKDLPEDLTAGLSALARAERVTLSAVTQGAWA
                     VLLSSRTREREVLFGATVAGR"
     protocluster    1..3208
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3207](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..3207
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3208
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3208
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS_motif       199..288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0001"
                     /evalue="4.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg427_1"
                     /protein_end="96"
                     /protein_start="66"
                     /score="41.4"
                     /tool="antismash"
                     /translation="PEGFPGELFIGGAGLARGYIASPALTSERFI"
     CDS_motif       370..435
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0002"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg427_1"
                     /protein_end="145"
                     /protein_start="123"
                     /score="36.6"
                     /tool="antismash"
                     /translation="FLGRLDSQVKIHGFRIEPGEIES"
     aSDomain        739..930
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg427_1_PCP.1"
                     /evalue="3.60E-24"
                     /label="ctg427_1_PCP.1"
                     /locus_tag="ctg427_1"
                     /protein_end="310"
                     /protein_start="246"
                     /score="76.5"
                     /tool="antismash"
                     /translation="EKTIAGIWADVLDLDSVGAHDNFFALGGDSIISIQAVSRAREAGL
                     SMTVRMLFEHPTVAQLALVC"
     aSModule        739..1890
                     /domains="nrpspksdomains_ctg427_1_PCP.1"
                     /domains="nrpspksdomains_ctg427_1_Epimerization.1"
                     /incomplete
                     /locus_tags="ctg427_1"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        973..1890
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg427_1_Epimerization.1"
                     /evalue="3.30E-145"
                     /label="ctg427_1_Epimerization.1"
                     /locus_tag="ctg427_1"
                     /protein_end="630"
                     /protein_start="324"
                     /score="476.5"
                     /tool="antismash"
                     /translation="TGEAPLTPIQRWFFSSEPAEPWHFNQSVLLEVPGRFEPALAVSAL
                     RAIISHHDALRLRFARTGGDWSQRIVGDGQSDTFTSVDLSNLEDCDFSTAVEAAASAAQ
                     AGLDISEGLLIRALHFSRGAESSGRLLLIIHHLAVDGVSWRILLSDLDRAYRQLLDGEE
                     ISLPAKSTSYPVWALRLEEYASSCRMAEEAAYWNDEAARLADPIPCDLPGTPDSNTVGS
                     SCTVSLELDEALTESLIRDIPPVYNTRINDALLTALGMALLRWTGRNVFTIDVEGHGRE
                     EIFDGMDVSRTVGWFTSLFPVTIEIS"
     CDS_motif       988..1014
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0003"
                     /evalue="2.50E-04"
                     /label="NRPS-E1"
                     /locus_tag="ctg427_1"
                     /protein_end="338"
                     /protein_start="329"
                     /score="13.9"
                     /tool="antismash"
                     /translation="LTPIQRWFFS"
     CDS_motif       1048..1149
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0004"
                     /evalue="3.70E-06"
                     /label="C2_dual_024-063"
                     /locus_tag="ctg427_1"
                     /protein_end="383"
                     /protein_start="349"
                     /score="19.5"
                     /tool="antismash"
                     /translation="QSVLLEVPGRFEPALAVSALRAIISHHDALRLRFA"
     CDS_motif       1360..1425
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0005"
                     /evalue="5.90E-11"
                     /label="NRPS-E2"
                     /locus_tag="ctg427_1"
                     /protein_end="475"
                     /protein_start="453"
                     /score="34.5"
                     /tool="antismash"
                     /translation="LLLIIHHLAVDGVSWRILLSDLD"
     CDS_motif       1834..1884
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0006"
                     /evalue="1.40E-08"
                     /label="NRPS-E5"
                     /locus_tag="ctg427_1"
                     /protein_end="628"
                     /protein_start="611"
                     /score="26.7"
                     /tool="antismash"
                     /translation="DVSRTVGWFTSLFPVTIE"
     aSDomain        1909..2364
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg427_1_TIGR01720.1"
                     /evalue="1.60E-46"
                     /label="ctg427_1_TIGR01720.1"
                     /locus_tag="ctg427_1"
                     /protein_end="788"
                     /protein_start="636"
                     /score="149.7"
                     /tool="antismash"
                     /translation="GSDLKSVKERLRSIPDKGIGYGILRYLAADRQLLISGRSEAQVSF
                     NYLGQVDSAFADGEFRIAAESAGNDTSPAMVRRHLIDVTGIVSSGRLSLNITYSRHFHR
                     RETAERLAEWLEESLRELVRHCMTPGAGGRTPSDFPLASLAQSDLDRLF"
     CDS_motif       1927..1989
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0007"
                     /evalue="2.90E-12"
                     /label="NRPS-E6"
                     /locus_tag="ctg427_1"
                     /protein_end="663"
                     /protein_start="642"
                     /score="38.6"
                     /tool="antismash"
                     /translation="VKERLRSIPDKGIGYGILRYLA"
     aSDomain        2386..3207
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg427_1_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="3.50E-91"
                     /label="ctg427_1_Condensation_DCL.1"
                     /locus_tag="ctg427_1"
                     /protein_end="1069"
                     /protein_start="795"
                     /score="297.2"
                     /tool="antismash"
                     /translation="EDLYPLTPMQQGLLFHALRSPDSDMYREQASCMLTGDLDSAAFQR
                     AWQSVVDRHSVLRTYFIWEDMSEPLQAVKRRATLPWIEEDWRHLGAGELEKRRRELLGG
                     SGRRALDLKSAPVANAHLARLDDRKWLFVWCHHHTLMDGWSFPIVLREVFSLYRSYMDR
                     TDSALPPPRPYRDYIEWMRAQDMGRSEAFWREELRGFTAPTLLASDRRAEEPGIGMELV
                     KDLPEDLTAGLSALARAERVTLSAVTQGAWAVLLSSRTREREVLFGATVAGR"
     aSModule        2386..3207
                     /domains="nrpspksdomains_ctg427_1_Condensation_DCL.1"
                     /incomplete
                     /locus_tags="ctg427_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2395..2433
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0008"
                     /evalue="4.40E-05"
                     /label="C1_dual_004-017"
                     /locus_tag="ctg427_1"
                     /protein_end="811"
                     /protein_start="798"
                     /score="16.1"
                     /tool="antismash"
                     /translation="YPLTPMQQGLLFHA"
     CDS_motif       2455..2574
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0009"
                     /evalue="2.90E-17"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg427_1"
                     /protein_end="858"
                     /protein_start="818"
                     /score="54.9"
                     /tool="antismash"
                     /translation="DMYREQASCMLTGDLDSAAFQRAWQSVVDRHSVLRTYFIWE"
     CDS_motif       2791..2856
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0010"
                     /evalue="3.10E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg427_1"
                     /protein_end="952"
                     /protein_start="930"
                     /score="35.7"
                     /tool="antismash"
                     /translation="HHHTLMDGWSFPIVLREVFSLYR"
     CDS_motif       2902..2940
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg427_1_0011"
                     /evalue="2.80E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="ctg427_1"
                     /protein_end="980"
                     /protein_start="967"
                     /score="10.4"
                     /tool="antismash"
                     /translation="PYRDYIEWMRAQDM"
ORIGIN
        1 gcgctctcat gggctctgca gcagaagttc ttcgaggtgt ccggagcgga gctatacaac
       61 ctctatgggc cgacagaggc gtctgttgac gtgtcgttct ggcggtgcga tccggacggc
      121 cctgaaggaa cagtgccgat aggatacccg atagcgaata catccctcca tatcctggac
      181 aggaatatga accccgtccc ggaggggttt ccaggcgagc tcttcatagg cggcgccggg
      241 ctggcccgcg gatatatcgc atcacctgcc ttgacttccg aaaggttcat cgcagaccct
      301 ttcaccacag gcggacgcct gtacaggaca ggagacaggg cgaggcgcct tcccggcggc
      361 gcgatagagt tcctgggccg gcttgacagc caggtcaaga tacacgggtt ccgcatagag
      421 cccggcgaga tcgagtctgc gctcctctcc cattccgcaa ttcgcgactg cgccgtcgtg
      481 gcaagggagg acaggccggg catcaggcgc ctcgtggcat acgcagtcct gaaggacagc
      541 gccgaaagcc ctgggagcat caagaccgag ctggacgcca tagccggcga aaagcttcct
      601 ccatatatga agccctcggc ctatgtgatc cttccagcgc tccctttgac ggcgagcggc
      661 aaaacagaca ggaaggccct ccctgtcccg gagccggcag caggcctgga tgcttcagcg
      721 ccgccacgca cgtccgcaga gaagaccatc gccggcatat gggctgatgt gctcgacctg
      781 gacagtgtcg gggcgcacga caacttcttc gcgctcggag gagactcgat aataagcatc
      841 caggcagtgt cacgcgccag ggaggcaggc ctctccatga ccgtcaggat gctctttgag
      901 cacccgacag tcgcacagct ggcgctggtc tgcggcggaa tgccggccct ggaggccgag
      961 cagggtatcg tgacaggcga agctcctctc acgccgatcc agagatggtt cttcagcagc
     1021 gagccggcag agccatggca tttcaatcag tctgtgctgc tcgaagtgcc tggccgcttc
     1081 gagccggcgc tcgccgtttc cgctctccgg gccataatct cccatcacga cgctctccgc
     1141 ctccgcttcg cccggacagg cggggactgg tcgcagagaa tcgtcggaga cgggcagtcc
     1201 gacacattca catcagtcga tctctcgaat ctcgaggatt gcgacttttc aacagcagtt
     1261 gaagcagcgg cgtcagccgc tcaggcgggc ctcgatatct cggaaggcct gctgatcagg
     1321 gcgttgcact tctcgagagg ggcggagagc tccggcaggc tccttctgat catccatcat
     1381 cttgcagtgg acggagtgtc gtggcgcata ctgctctccg atctggatcg cgcatacagg
     1441 cagctcctcg acggggagga gatctcactc cctgcaaaga gcacgtcata tcctgtctgg
     1501 gcattgcgtc tcgaagaata tgcctcttcc tgcaggatgg ccgaagaagc ggcatattgg
     1561 aatgatgagg cagccaggct ggcagatcca atcccctgcg atctgccggg aactccggat
     1621 tcgaacacag tcggctcgag ctgcacggtg tcgctggagc tggatgaggc gctgaccgaa
     1681 tcactgatca gggacatacc gcctgtctac aataccagga taaacgacgc gctcctgaca
     1741 gcgctcggga tggcgctcct cagatggaca gggaggaatg tcttcacgat agacgtggaa
     1801 ggccacggcc gggaggagat attcgacggt atggacgtca gccgcacagt cggatggttt
     1861 acgagcctgt tcccggtaac gattgagata tcgggcaggg cagatcccgg ctcagatctc
     1921 aagagcgtaa aagaaaggct ccgctcgatc cctgacaagg ggatcggata cggcatcctc
     1981 agatatcttg ccgcagacag gcagctgctg atttcaggcc gctctgaggc gcaggtaagc
     2041 tttaactacc tgggtcaggt ggacagcgcc ttcgcagacg gagagttcag gatcgccgcc
     2101 gagagcgccg gaaatgacac gagccctgcg atggtccgca ggcacctgat cgatgtgaca
     2161 gggatcgtct cttcaggcag gctcagcctg aacatcactt acagcaggca tttccaccgg
     2221 cgcgagaccg cagagaggct ggccgaatgg ctggaagagt ctctcagaga gcttgtcagg
     2281 cactgcatga ctccaggcgc gggaggtcgc acgccttccg acttcccgct cgcgtcgctc
     2341 gcccagtccg atctggaccg cctctttgcc ggacatgagc agattgaaga cctgtatccg
     2401 ttgacgccga tgcagcaggg cctcctgttt cacgccctgc gcagccctga ttccgacatg
     2461 taccgcgagc aggcgagctg catgctgacg ggcgatctgg acagcgccgc gttccagagg
     2521 gcctggcagt ccgtcgtgga caggcattcc gtgctgagga catacttcat atgggaggat
     2581 atgagcgagc ctctgcaggc ggtaaagcgc cgcgcaacgc tgccctggat tgaggaggac
     2641 tggagacatc tcggcgcagg cgagctggag aaacggcggc gcgagctgct gggaggctca
     2701 ggcaggagag ctctcgacct gaagagcgcc cctgttgcga acgcccatct cgcgaggctc
     2761 gacgacagaa aatggctctt cgtgtggtgc caccaccaca cgctgatgga cggatggtct
     2821 ttcccgatag tgctccgcga agtcttttcg ctttaccggt catatatgga caggaccgac
     2881 agcgcgctcc cgccgccccg cccctaccgc gattacatcg aatggatgag agcgcaggat
     2941 atgggcagat cagaggcgtt ctggcgggaa gagctgcggg gattcacggc tccgaccctc
     3001 ctggcctccg acaggcgcgc cgaagagccg ggcatcggca tggagctcgt gaaggatctt
     3061 ccggaagatc tcaccgcagg tctttcggct ctggcaaggg ccgagagagt gactctgagc
     3121 gcggtaacgc agggcgcgtg ggctgtgctt ctttcaagcc gcaccaggga aagagaggtt
     3181 ctctttggcg ccacggtggc gggaaggc
//
