LOCUS       c00324_3300028..        4574 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300028999.a:Ga0169655_101931.
ACCESSION   c00324_3300028..
VERSION     c00324_3300028..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 07:27:20
            Original ID  :: 3300028999.a:Ga0169655_101931
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4574
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1290
                     /NRPS_PKS="Domain: Condensation_Starter (2-285). E-value:
                     5.3e-28. Score: 89.9. Matches aSDomain:
                     nrpspksdomains_ctg324_1_Condensation_Starter.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     98.5; E-value: 8.3e-30)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg324_1"
                     /sec_met_domain="Condensation (E-value: 6.5e-21, bitscore:
                     63.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SVQAELDFGLLKKCIQMETERSGCTRVRFTKPDKEGNVKQYIEKQ
                     DPRDIELKDLSGMESLAKADELMQQWAYETFDGNNIPMCEFTMLKLPEGYNGFFLHMDH
                     RLIDSCGLVVMIEDLFQLYTHYRYGTACPQELVDFETVLKKDLAKAGNEKRFAKDKKFW
                     DDQLDALGEPLYSDIQGPSVLEEARKRHGNPKLRASDIEMNELFVAVKDYHLEPYATQN
                     LMDFCMNHQLSMTNLLLLGIRTYLSKVNNGQEDITIQNFISRRSTHDEWTSGGSRTIMF
                     PCRTVISPETDFLSAAYEIQNMQNRIYMHSNYDPAFIVDEMRKRYHTPEHTSYESCYLT
                     YQPMPVKVENEMLGTIRQHAKWFANGAATKKMYLTVSHTEDGGMNFSYHYQTAHLEEHD
                     MELLYYYMMRILFKGIAEPDMSIGEIMEQV"
     protocluster    1..4574
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3242]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..3242
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4574
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4574
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     aSDomain        7..855
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg324_1_Condensation_Starter.1"
                     /domain_subtype="Condensation_Starter"
                     /evalue="5.30E-28"
                     /label="ctg324_1_Condensation_Starter.1"
                     /locus_tag="ctg324_1"
                     /protein_end="285"
                     /protein_start="2"
                     /score="89.9"
                     /tool="antismash"
                     /translation="QAELDFGLLKKCIQMETERSGCTRVRFTKPDKEGNVKQYIEKQDP
                     RDIELKDLSGMESLAKADELMQQWAYETFDGNNIPMCEFTMLKLPEGYNGFFLHMDHRL
                     IDSCGLVVMIEDLFQLYTHYRYGTACPQELVDFETVLKKDLAKAGNEKRFAKDKKFWDD
                     QLDALGEPLYSDIQGPSVLEEARKRHGNPKLRASDIEMNELFVAVKDYHLEPYATQNLM
                     DFCMNHQLSMTNLLLLGIRTYLSKVNNGQEDITIQNFISRRSTHDEWTSGGSRTIMFPC
                     RTV"
     aSModule        7..855
                     /domains="nrpspksdomains_ctg324_1_Condensation_Starter.1"
                     /incomplete
                     /locus_tags="ctg324_1"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS             1388..1618
                     /NRPS_PKS="Domain: PP-binding (6-69). E-value: 2.4e-12.
                     Score: 39.0. Matches aSDomain:
                     nrpspksdomains_ctg324_2_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg324_2"
                     /sec_met_domain="PP-binding (E-value: 2.4e-13, bitscore:
                     39.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQEMEFKNIVAQYSKVKPEEMTGEMRFREDLGFTSLDFMSFLGE
                     LEDTFDIELDENEVTKIITLEEALKLLEELQ"
     aSDomain        1406..1594
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg324_2_PP-binding.1"
                     /evalue="2.40E-12"
                     /label="ctg324_2_PP-binding.1"
                     /locus_tag="ctg324_2"
                     /protein_end="69"
                     /protein_start="6"
                     /score="39.0"
                     /tool="antismash"
                     /translation="FKNIVAQYSKVKPEEMTGEMRFREDLGFTSLDFMSFLGELEDTFD
                     IELDENEVTKIITLEEALK"
     aSModule        1406..1594
                     /domains="nrpspksdomains_ctg324_2_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg324_2"
                     /tool="antismash"
                     /type="unknown"
     CDS             1698..3242
                     /NRPS_PKS="Domain: AMP-binding (7-410). E-value: 2.1e-80.
                     Score: 262.0. Matches aSDomain:
                     nrpspksdomains_ctg324_3_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     247.2; E-value: 4.5e-75)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg324_3"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-89, bitscore:
                     287.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIRNILEESVQKFGEVKAVKWLNRKEVLEKSYSEMMKNVISTRK
                     GLLAEGFEGKHIALIGTSSVEWIESYLGIITGCATAVPLDAALPCEELIDLINRSDSEA
                     LFLSPKHRPYLEAFLANCPKLQKVWMLQKEVEDLPSGVYSINELRDMGKSAAEDASCPD
                     AEAIATIIFTSGTTGKSKGVMLTQNNLASNVEAVKISAEPGTAMLSVLPIHHAFCLVMD
                     WLKGFSQGATICINDSLLHMVRNMSIFKPDIMLMVPMMIETIYKRLAAADPEIPKAVLA
                     EKVFGGKLQTIFTGGAHLDPYYIDRFAEYGVQILEGYGMSECSPVISNNTPENHKPGSI
                     GKPLENVEIKFENGEILVKGTSVMKGYYQMPEETAETLKDGWLHTGDKGYMDEDGYLFI
                     NGRVKNLIILSNGENVSPEELENKLALNPLVAEVIVTGEENGLTARIYPEQAVVEAKAL
                     DTEMIRLQLQAFLDVYNKNQPTYRRITGLVIRKNPFIRSTTKKIRRQDVLIDEPQA"
     aSDomain        1719..2927
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg324_3_AMP-binding.1"
                     /evalue="2.10E-80"
                     /label="ctg324_3_AMP-binding.1"
                     /locus_tag="ctg324_3"
                     /protein_end="410"
                     /protein_start="7"
                     /score="262.0"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="EESVQKFGEVKAVKWLNRKEVLEKSYSEMMKNVISTRKGLLAEGF
                     EGKHIALIGTSSVEWIESYLGIITGCATAVPLDAALPCEELIDLINRSDSEALFLSPKH
                     RPYLEAFLANCPKLQKVWMLQKEVEDLPSGVYSINELRDMGKSAAEDASCPDAEAIATI
                     IFTSGTTGKSKGVMLTQNNLASNVEAVKISAEPGTAMLSVLPIHHAFCLVMDWLKGFSQ
                     GATICINDSLLHMVRNMSIFKPDIMLMVPMMIETIYKRLAAADPEIPKAVLAEKVFGGK
                     LQTIFTGGAHLDPYYIDRFAEYGVQILEGYGMSECSPVISNNTPENHKPGSIGKPLENV
                     EIKFENGEILVKGTSVMKGYYQMPEETAETLKDGWLHTGDKGYMDEDGYLFINGRVKNL
                     IILSN"
     aSModule        1719..2927
                     /domains="nrpspksdomains_ctg324_3_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg324_3"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2199..2255
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg324_3_0001"
                     /evalue="9.80E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg324_3"
                     /protein_end="186"
                     /protein_start="167"
                     /score="24.3"
                     /tool="antismash"
                     /translation="ATIIFTSGTTGKSKGVMLTQ"
     CDS_motif       2757..2825
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg324_3_0002"
                     /evalue="1.20E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg324_3"
                     /protein_end="376"
                     /protein_start="353"
                     /score="20.8"
                     /tool="antismash"
                     /translation="GEILVKGTSVMKGYYQMPEETAET"
     CDS             complement(3352..3930)
                     /locus_tag="ctg324_4"
                     /transl_table=11
                     /translation="MQNPVPDERYSVADEAILGAFFKLLKKKTPDQITVSDITKIAGIA
                     RSTFYNHYQDIPSLVSAVEEKTIQDVFSIMEKFHPENDRDICQSYFLTLCRYTMENPFL
                     SSLLSTPHGNDLFEKMLTMLHHYVTATTSSARPGRHTKEEISYVITCAIGSTIGVLHKW
                     TRDHFDLEPEVIAEILTQVFLTGMLPLLS"
     CDS             complement(4032..4574)
                     /locus_tag="ctg324_5"
                     /transl_table=11
                     /translation="PYDYISINKGTVVSRGQIDHIENCTYHMKDGVRLEGRKRGAATHK
                     FLNKSLHQDPTKILSPNIRTRFSVVDDMPLAFCVIELIFNKNGTGIDFVFRYCNKEMLL
                     LEGMDLQEILDQSFYQAFPNGDKKLLAAYTDVAVNGGSCRLKTYSARIHRELIIKCFQP
                     LENFCACILIPAYEIEK"
ORIGIN
        1 tctgtacagg cagaactgga ttttggatta ttaaaaaaat gtattcagat ggaaacagag
       61 cgttccggtt gtaccagagt ccgttttaca aagccggata aagagggaaa tgtaaaacag
      121 tatatcgaaa aacaggaccc gcgtgatatt gagctgaagg atctgtcagg aatggaaagt
      181 ctggcaaagg cagatgagct gatgcagcag tgggcatatg aaacatttga cggaaataat
      241 attcccatgt gtgaatttac catgctgaag cttccagaag gatacaatgg tttcttttta
      301 catatggatc acagactgat cgattcctgt ggacttgtag ttatgatcga agatctgttc
      361 caattatata cgcattacag atatggaacc gcctgccctc aggaactggt agattttgaa
      421 acggttctga aaaaagacct ggcaaaggcg ggcaatgaaa agcgttttgc aaaagataaa
      481 aaattctggg atgaccagct ggatgcactg ggtgagccgt tatattctga tattcaggga
      541 ccgtccgtat tggaggaagc aagaaaacgc catggaaatc cgaagcttcg tgcttctgac
      601 attgagatga acgagctgtt tgttgcagta aaggattatc atctggaacc gtatgcgaca
      661 cagaacctga tggatttctg tatgaatcat cagctttcta tgacaaatct gcttctgctt
      721 ggtatccgta cttatctgtc aaaagtaaat aatggacagg aggatattac aatccagaat
      781 tttatatcca gacgttctac ccatgacgaa tggacttcag gaggaagccg aaccattatg
      841 tttccatgca gaacagtgat ctcaccagag acagattttc tttcggcagc ttatgaaatt
      901 cagaatatgc agaatcgaat ttatatgcac agcaattatg atccggcatt tattgtggat
      961 gagatgagaa aaagatatca tacaccggag cataccagtt atgaaagctg ctatctgacc
     1021 tatcagccaa tgccggtgaa ggtggagaat gaaatgcttg gaactattcg ccagcatgcc
     1081 aaatggtttg caaacggtgc tgcaaccaag aaaatgtatc tgaccgtatc tcacaccgag
     1141 gatgggggaa tgaacttctc ctatcattat cagactgctc atctggagga gcatgacatg
     1201 gaactgttgt attattatat gatgcgtatt ctttttaaag ggattgcaga gccggatatg
     1261 agcattggag agattatgga acaggtataa agtgtaacag gtcccacaaa gcttgaagga
     1321 gtaagaacgg ttaaagagaa cctgttggca ttgtttttat agaaatcaaa aatcaggagg
     1381 aaatggaatg agtcaggaaa tggaatttaa aaatattgta gcacagtaca gtaaagtgaa
     1441 accggaagag atgacaggtg agatgagatt tcgtgaggat ctgggattta cttccctgga
     1501 ttttatgtct ttcctgggtg agcttgagga tacctttgat attgaactgg atgaaaacga
     1561 agtgacaaaa attataactc ttgaggaggc acttaagctt cttgaggagc ttcagtagga
     1621 cttaacatta ctgttcccgg agtgaacagt aagaattaac agagtgtcag ttcactgaac
     1681 agtgaaggag gaaaaatatg ctgatcagga atatattaga agaaagtgta cagaaatttg
     1741 gcgaagtcaa agcagtaaaa tggcttaacc gaaaagaagt tctggagaaa agttacagcg
     1801 aaatgatgaa aaacgtgatt tctaccagaa aaggacttct tgcagaaggg tttgagggaa
     1861 aacatattgc attaatcgga accagttctg tagaatggat cgaaagctat ctgggaatta
     1921 ttacaggatg cgctacagcg gtgccgctgg atgctgcact cccgtgtgaa gaactgattg
     1981 acctgataaa tcgctccgat tccgaagcac tcttcttaag tccgaaacac agaccatatc
     2041 tggaagcatt tcttgcaaac tgtcccaagc ttcagaaggt gtggatgctc cagaaagagg
     2101 tggaggatct gccttcagga gtgtacagta tcaatgagct gagagatatg ggaaagagtg
     2161 cagcagaaga tgcttcctgt ccggatgcag aagctattgc gactattatc tttacttccg
     2221 gaaccacagg aaagagcaaa ggggttatgc tgacacagaa taatctggca tccaacgttg
     2281 aggcagttaa gatttcagca gagcctggaa ctgccatgct cagtgtactt ccaatccatc
     2341 atgcattctg ccttgtcatg gactggctga aaggattttc tcagggggca actatctgta
     2401 tcaatgactc cctgcttcat atggtcagaa atatgagcat ttttaaacca gatatcatgc
     2461 tcatggttcc gatgatgatt gagacaattt ataagagact agcggctgct gatccggaaa
     2521 tcccgaaggc ggttcttgca gaaaaagtat tcggcggaaa actgcagacg atttttaccg
     2581 gcggggcaca tctggatccg tactatattg accgttttgc agaatatggc gttcagatac
     2641 tggaaggata tggcatgtcg gaatgttctc ctgttatcag taataataca ccggaaaatc
     2701 ataaaccggg ttctatcgga aaaccacttg agaatgtgga gataaagttt gaaaacgggg
     2761 agattctggt aaagggtaca agtgttatga aagggtacta tcagatgccg gaggagacag
     2821 cggaaacact gaaggatggc tggctgcata caggcgacaa gggctatatg gatgaagatg
     2881 gatacctctt tattaacggt cgtgtgaaaa atctgatcat tctctccaat ggggaaaatg
     2941 tatcaccgga agaacttgag aacaagcttg cgttgaatcc acttgttgcg gaagtgattg
     3001 taacaggtga agagaatggt ctgacagcac gcatctatcc ggaacaggca gttgtggagg
     3061 caaaggcact ggatactgag atgattcgtt tacagcttca ggcatttctg gatgtataca
     3121 ataaaaatca gccgacctat cgtcgcatta caggtctggt gatccggaaa aatccgttta
     3181 tacgcagtac aacaaagaaa atcaggagac aggatgtcct gattgatgag ccacaggcat
     3241 aagaaaaacc cgtctgagtg aattgcttag acgggttttt cttatgcctg tttgaaagag
     3301 cattcccgca atctgcacgc tccactttgc gggaatgctt tttcaaacac gtcaggataa
     3361 aagaggcagc atgccagtca ggaaaacctg agtcagaatc tctgcaatga cttctggttc
     3421 aagatcaaaa tgatcccggg tccatttgtg aagaacaccg atcgtgctgc caatcgcaca
     3481 ggtgatcaca taagatattt cctcttttgt gtgtctgccg ggtctggcac tggaggtagt
     3541 agcggtgaca tagtgatgaa gcatagtcag cattttttca aagagatcat tcccatgggg
     3601 tgtgctcaga agactggaaa ggaaaggatt ttccattgta tagcggcaaa gtgtcagaaa
     3661 ataggactga cagatatctc ggtcattttc aggatgaaat ttttccatta tagaaaaaac
     3721 atcctggatc gtcttttcct caactgcgga tacaagagaa ggaatgtctt gataatgatt
     3781 ataaaaagtg cttctcgcga taccagctat cttagtgata tcggatactg tgatctgatc
     3841 aggagttttt ttctttagaa gtttaaaaaa agcacccagg atggcttcat ccgctacaga
     3901 atatctttcg tcaggaactg gattttgcat agtcgattcc ctcccaatat tttatcaata
     3961 aatataagga tatgagtggc aaaagacctt ttgactctca tatcatgtat atatggaaat
     4021 ctggaaaatg tttatttctc tatttcatag gcaggaatca atatacatgc gcagaagttt
     4081 tccaatggct ggaaacattt gataataagt tcacgatgaa tcctggcact gtaagtcttg
     4141 agacgacagc ttccgccatt cacggcaaca tctgtatatg cggcaaggag cttcttatct
     4201 ccgttgggaa atgcctgata aaaagactgg tcgagtattt cctgcaaatc catgccttcc
     4261 agaagaagca tttctttatt gcaatagcgg aaaacgaagt caattccagt tccgttttta
     4321 ttaaaaatca gttcgattac acaaaaagca aggggcatat catctactac agaaaaacgc
     4381 gtacgaatat ttggagataa aatcttggta ggatcctgat gcaaagattt gttcagaaat
     4441 ttgtgagtgg ctgcgccacg cttacgtcct tccagacgta cgccatcctt catatgatag
     4501 gtgcagtttt cgatatgatc aatctgtcct ctggaaacca cggtgccttt atttatggaa
     4561 atataatcat aagg
//
