LOCUS       c00031_3300029..        4078 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300029906.a:Ga0247342_1009624.
ACCESSION   c00031_3300029..
VERSION     c00031_3300029..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 05:13:34
            Original ID  :: 3300029906.a:Ga0247342_1009624
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4078
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4078
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[246:4077](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      247..4077
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4078
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4078
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             247..4077
                     /NRPS_PKS="Domain: ACP (279-348). E-value: 3.1e-14. Score:
                     44.8. Matches aSDomain: nrpspksdomains_ctg31_1_ACP.1"
                     /NRPS_PKS="Domain: Heterocyclization (370-669). E-value:
                     5.4e-107. Score: 349.3. Matches aSDomain:
                     nrpspksdomains_ctg31_1_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (840-1241). E-value:
                     1.9e-94. Score: 308.3. Matches aSDomain:
                     nrpspksdomains_ctg31_1_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     171.4; E-value: 6.2e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_1"
                     /sec_met_domain="Condensation (E-value: 4.1e-49, bitscore:
                     153.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-111, bitscore:
                     358.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.1e-14, bitscore:
                     38.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 2.3e-10, bitscore:
                     26.7, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEPILSGLHEECGVFGVYDPKGGCAQTTYYGLYALQHRGQEACGI
                     AAINGREQSFYKDVGLVSEVFDKETLDRLNGTMAVGHVRYATTGAGERENAQPLTIKYV
                     KGTLAVVHNGNLVGVDQLRRDFEYKGAIFHTTSDSELIAYAIAQARRLAPSADILAMRP
                     GDLPDGNTADTPLLLPAFAPDAAATPQHMAAVLACCWTRGTNVRWAAVHAGSAARRIPL
                     PTYPFARERFWFGGTDMTDAPAALPARRSPAPLEIPDVSCVMQETARADRLDDAELLAL
                     LSREARAVLRLPENVSLSPETPLVRAGFDSLLFMELAQRLSRRLGMTLPPALLMETATL
                     AALRERLCLQGQTAPAPQAMTDIVARPEDRHLPFPLTDVQHAYWIGRDGSMTLGGVSCS
                     NYVEADFTGLDVPRLEKALDALVRRHDMLRCVITPDGRQRVLPAVPACRIPLEDLSALP
                     EEEKERVLRQKREQLSHKVLPTDKAPLLEITASRLDAATIRLHVKLDLLVADAYSFGIL
                     MQDLAAWYADPGMEKSPLSLSFRDCVLAAEAEKDTPAWQADREYWLQRLPFLPAGPELP
                     LARTPQSLGTPRFHRRTAMLDAARWARLKEMGRAQGLTPSGLLLAAFSLVLSRWTAQPH
                     FCLMLTTFDRRYRHEEMGAVVGDFTRLLLLEVQREKGATFLEHATALGRQLIRDMGHSR
                     FSAVDVLRELAKDHGEDMTSSRSAVVFTSALPLSGDDPFAAADGLGAKLAYAVSQTPQV
                     WLDHQVCEYRGQLVYTWDAVEDLFPSGMLDAMFTVYGDFLTALCEDAALWQQPVPLHRL
                     PAAQADVRHAANATEAAIPPRTLFAPFLDHASRDGAPAAVIGEGVSLSRAEAESISRLL
                     GNGLRSRGLRPGEIVAVMMEKGWEQVVAVMGILRAGGAYLPVSPSLPDKRIAYMFKDAG
                     VRFCFVQPGLEARAEACGSEAVPVLRAFPEQAAPAAAPLPDTDVSPEGLAYVIYTSGST
                     GLPKGVMVSHAAAHNTLADLGQRLGLGPRDRVIALASLSFDLSVFDLFGVTAAGGAVVI
                     PAPGQERDPAAWCRLMREQGVTVWNSTPSLMQLLLDYLDDHPEDRPEQLRLALLSGDWI
                     PLAMPDRMHALWPDMTVAALGGATEAAIWSNIQIVDHIPAEWHSIPYGRPLANQGYLVF
                     DQDLCPCPDLVAGDLYITGAGLARGYLNDPSKTAAAFFRHPRSGQALYRTGDLGRYWPD
                     GTLEFLGRKDSQVKINGFRIELGEVERALNALPGVGNAAVIALRSDKGDRLA"
     aSDomain        1084..1290
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg31_1_ACP.1"
                     /evalue="3.10E-14"
                     /label="ctg31_1_ACP.1"
                     /locus_tag="ctg31_1"
                     /protein_end="348"
                     /protein_start="279"
                     /score="44.8"
                     /tool="antismash"
                     /translation="ALLSREARAVLRLPENVSLSPETPLVRAGFDSLLFMELAQRLSRR
                     LGMTLPPALLMETATLAALRERLCL"
     aSModule        1084..1290
                     /domains="nrpspksdomains_ctg31_1_ACP.1"
                     /incomplete
                     /locus_tags="ctg31_1"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        1357..2253
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg31_1_Heterocyclization.1"
                     /evalue="5.40E-107"
                     /label="ctg31_1_Heterocyclization.1"
                     /locus_tag="ctg31_1"
                     /protein_end="669"
                     /protein_start="370"
                     /score="349.3"
                     /tool="antismash"
                     /translation="HLPFPLTDVQHAYWIGRDGSMTLGGVSCSNYVEADFTGLDVPRLE
                     KALDALVRRHDMLRCVITPDGRQRVLPAVPACRIPLEDLSALPEEEKERVLRQKREQLS
                     HKVLPTDKAPLLEITASRLDAATIRLHVKLDLLVADAYSFGILMQDLAAWYADPGMEKS
                     PLSLSFRDCVLAAEAEKDTPAWQADREYWLQRLPFLPAGPELPLARTPQSLGTPRFHRR
                     TAMLDAARWARLKEMGRAQGLTPSGLLLAAFSLVLSRWTAQPHFCLMLTTFDRRYRHEE
                     MGAVVGDFTRLLLLEVQRE"
     aSModule        1357..3969
                     /domains="nrpspksdomains_ctg31_1_Heterocyclization.1"
                     /domains="nrpspksdomains_ctg31_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg31_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1378..1407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0001"
                     /evalue="1.90E-03"
                     /label="Cy1"
                     /locus_tag="ctg31_1"
                     /protein_end="387"
                     /protein_start="377"
                     /score="10.8"
                     /tool="antismash"
                     /translation="DVQHAYWIGRD"
     CDS_motif       1507..1560
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0002"
                     /evalue="6.70E-10"
                     /label="Cy2"
                     /locus_tag="ctg31_1"
                     /protein_end="438"
                     /protein_start="420"
                     /score="31.0"
                     /tool="antismash"
                     /translation="LVRRHDMLRCVITPDGRQR"
     CDS_motif       1741..1785
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0003"
                     /evalue="5.70E-05"
                     /label="Cy3"
                     /locus_tag="ctg31_1"
                     /protein_end="513"
                     /protein_start="498"
                     /score="16.3"
                     /tool="antismash"
                     /translation="RLHVKLDLLVADAYSF"
     CDS_motif       2080..2139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0004"
                     /evalue="1.60E-08"
                     /label="Cy4"
                     /locus_tag="ctg31_1"
                     /protein_end="631"
                     /protein_start="611"
                     /score="27.2"
                     /tool="antismash"
                     /translation="GLTPSGLLLAAFSLVLSRWTA"
     CDS_motif       2191..2247
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0005"
                     /evalue="1.10E-06"
                     /label="Cy5"
                     /locus_tag="ctg31_1"
                     /protein_end="667"
                     /protein_start="648"
                     /score="21.0"
                     /tool="antismash"
                     /translation="HEEMGAVVGDFTRLLLLEVQ"
     CDS_motif       2311..2358
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0006"
                     /evalue="6.10E-05"
                     /label="afterCy5"
                     /locus_tag="ctg31_1"
                     /protein_end="704"
                     /protein_start="688"
                     /score="15.8"
                     /tool="antismash"
                     /translation="DMGHSRFSAVDVLRELA"
     CDS_motif       2485..2529
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0007"
                     /evalue="1.40E-07"
                     /label="Cy7"
                     /locus_tag="ctg31_1"
                     /protein_end="761"
                     /protein_start="746"
                     /score="24.2"
                     /tool="antismash"
                     /translation="VSQTPQVWLDHQVCEY"
     aSDomain        2767..3969
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg31_1_AMP-binding.1"
                     /evalue="1.90E-94"
                     /label="ctg31_1_AMP-binding.1"
                     /locus_tag="ctg31_1"
                     /protein_end="1241"
                     /protein_start="840"
                     /score="308.3"
                     /specificity="consensus: cys"
                     /tool="antismash"
                     /translation="DHASRDGAPAAVIGEGVSLSRAEAESISRLLGNGLRSRGLRPGEI
                     VAVMMEKGWEQVVAVMGILRAGGAYLPVSPSLPDKRIAYMFKDAGVRFCFVQPGLEARA
                     EACGSEAVPVLRAFPEQAAPAAAPLPDTDVSPEGLAYVIYTSGSTGLPKGVMVSHAAAH
                     NTLADLGQRLGLGPRDRVIALASLSFDLSVFDLFGVTAAGGAVVIPAPGQERDPAAWCR
                     LMREQGVTVWNSTPSLMQLLLDYLDDHPEDRPEQLRLALLSGDWIPLAMPDRMHALWPD
                     MTVAALGGATEAAIWSNIQIVDHIPAEWHSIPYGRPLANQGYLVFDQDLCPCPDLVAGD
                     LYITGAGLARGYLNDPSKTAAAFFRHPRSGQALYRTGDLGRYWPDGTLEFLGRKDSQVK
                     ING"
     CDS_motif       2947..2985
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0008"
                     /evalue="1.20E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg31_1"
                     /protein_end="913"
                     /protein_start="900"
                     /score="12.4"
                     /tool="antismash"
                     /translation="MGILRAGGAYLPVS"
     CDS_motif       3184..3243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0009"
                     /evalue="8.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg31_1"
                     /protein_end="999"
                     /protein_start="979"
                     /score="33.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGLPKGVMVSHA"
     CDS_motif       3358..3387
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0010"
                     /evalue="4.10E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg31_1"
                     /protein_end="1047"
                     /protein_start="1037"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="GVTAAGGAVVI"
     CDS_motif       3769..3855
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0011"
                     /evalue="2.10E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg31_1"
                     /protein_end="1203"
                     /protein_start="1174"
                     /score="42.4"
                     /tool="antismash"
                     /translation="DLVAGDLYITGAGLARGYLNDPSKTAAAFF"
     CDS_motif       3934..3999
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg31_1_0012"
                     /evalue="5.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg31_1"
                     /protein_end="1251"
                     /protein_start="1229"
                     /score="37.6"
                     /tool="antismash"
                     /translation="FLGRKDSQVKINGFRIELGEVER"
ORIGIN
        1 cggtcttgtg gataaaagcc aaaaatgtcc gttcatcgtt cacagcacac ccctcctctc
       61 cgggctagat tgcgtcaaaa tagacatatc atacgagaaa gttccggaat ccaaggaaga
      121 tataggcgga gcagccaatc ctctctccct tgcatcggac ggctgtgcgg gagtataata
      181 agtttgtgaa cgacggcgct catggagagc gccgccttgt ctttttcagg aaggaagtgc
      241 gcggggatgg aacccatact gagcggcctg cacgaggagt gcggggtatt cggcgtctac
      301 gatccaaagg gcgggtgcgc ccaaaccacc tattacgggc tgtacgccct ccagcaccgg
      361 gggcaggagg cctgcggcat cgcggccatc aacggccggg agcagtcctt ttacaaggac
      421 gtgggcctgg tgagcgaggt ctttgacaag gagaccctgg acaggctcaa cggcaccatg
      481 gcggtgggcc atgtgcgcta cgccaccacc ggggccggcg agcgggagaa cgcccagccc
      541 ctgaccatca agtacgtgaa gggcaccctg gcggtggtcc acaacggcaa tctggtgggg
      601 gtggaccagc tccgccggga ctttgagtac aagggggcca ttttccacac caccagcgac
      661 tccgagctca tcgcctatgc catcgcccag gcccggcgcc ttgccccatc cgccgacatc
      721 ctggccatgc gtcccggcga ccttcccgac ggcaataccg cggacacgcc gctgctgctc
      781 cccgccttcg ctcccgatgc cgccgcgacg ccgcagcata tggccgcggt gctggcctgc
      841 tgctggacac gcggtacaaa cgtgcgctgg gctgccgtcc atgcgggcag tgctgcccgg
      901 cgcataccgt tgccgaccta tccttttgca cgcgagcgct tctggttcgg cggcacggac
      961 atgacagacg cccctgccgc cctgcccgca cgccgctctc ccgccccgct ggagatcccc
     1021 gacgtatcgt gcgtcatgca ggagacggcg cgtgcggacc gtcttgacga tgcggagctc
     1081 ctggcgctgc tttcccgcga ggcccgcgcc gtcctgcgcc tgcccgaaaa cgtctccctg
     1141 tcccctgaga cacccctggt cagggccggt ttcgattccc tgctgttcat ggagctggcg
     1201 caacgcctga gcagacgcct cggcatgacg ctgcctccag ccctgctcat ggaaactgcc
     1261 accctggccg ccttgcggga acgtctgtgc ctgcagggac agaccgctcc cgcccctcag
     1321 gcgatgacgg acatcgttgc ccgtcccgaa gacaggcacc tgcccttccc cctgacggac
     1381 gtgcagcacg cctactggat cggacgggac ggcagcatga cgctgggtgg cgtcagttgc
     1441 agcaattatg tggaagcgga cttcacggga ctggacgtcc cccggctgga aaaagccctg
     1501 gatgccctcg tcaggcggca tgacatgctg cgctgcgtca tcacgcctga cggacggcag
     1561 cgcgtcctgc ctgcggtccc tgcctgccgc atcccgctcg aagacctttc cgccctgccc
     1621 gaagaggaga aggaacgcgt cctccggcag aaacgggaac agctttccca caaggtactg
     1681 cccacggaca aggctcctct gctggagatc acggcgagcc gtctggatgc cgctaccata
     1741 cgcctgcacg tcaagctgga tctgctggtg gccgatgcct acagtttcgg catcctgatg
     1801 caggatctcg ccgcctggta tgccgacccg ggaatggaaa aaagccctct gtccctttcc
     1861 ttcagggatt gcgtcctggc ggccgaggcg gaaaaggaca cgcccgcctg gcaggcggac
     1921 agggagtact ggctgcagcg cctgcccttc ctgcccgcag gtcccgagct gcctctggca
     1981 cggacgccgc aaagcctcgg caccccccgc ttccatcgtc gcacggcgat gctggatgcc
     2041 gcacgctggg cccgcctcaa ggaaatgggg cgcgcacagg ggctcacgcc ctccggcctg
     2101 ctgctggcgg ccttcagcct cgtcctttcc cgctggacgg cgcaaccgca cttctgcctc
     2161 atgctcacga ccttcgaccg ccggtaccgg catgaggaaa tgggggccgt ggtgggggac
     2221 ttcacccgcc tgctgctgct cgaagtccaa agggaaaaag gcgccacctt cctggagcac
     2281 gcaacggctc tcggcaggca gctgatccgg gacatgggac acagccgttt ctccgccgtg
     2341 gacgttttgc gggaactggc aaaggatcac ggcgaggaca tgacgtcctc ccgctccgct
     2401 gtcgtcttca ccagcgccct gcccctcagc ggcgacgatc cgttcgccgc ggccgacggc
     2461 ctgggagcga agctggccta tgccgtctcc cagacgccgc aggtatggct ggaccatcag
     2521 gtctgcgaat accggggcca gctcgtctat acctgggatg cggtggaaga cctgttcccc
     2581 tcggggatgc tcgatgccat gttcaccgtc tacggcgact tcctcacggc cctgtgcgag
     2641 gatgccgctc tctggcagca gcctgtgccc ctgcaccggc tgcccgcagc acaggcagac
     2701 gtccgccatg cggccaatgc cacagaagcg gccatcccgc cgcgtacgct gttcgccccc
     2761 ttcctggacc acgcctcccg ggatggagcc cctgccgccg tcatcggcga aggcgtcagc
     2821 ctgtcccggg ccgaggccga atccatctcc cgcctgctgg ggaacgggct gcgttcgcgg
     2881 ggcctgcgtc ccggcgagat cgtggccgtc atgatggaaa agggctggga acaggtcgtg
     2941 gccgtcatgg gcatcctgcg ggccggggga gcctatctgc ccgtgtcccc ctccctgccg
     3001 gacaagcgca tcgcctacat gttcaaggat gccggtgtcc gcttctgctt cgtgcagccc
     3061 ggcctggaag ccagggccga agcctgcggc agcgaggccg tccccgtcct ccgcgccttc
     3121 ccggaacaag cggccccggc cgcggcgccc cttccggata cggacgtatc gccggagggc
     3181 ctggcctatg tcatctatac ctccggctcc acaggcctgc ccaagggggt gatggtcagc
     3241 catgccgcag cccacaatac tctggcggac ctggggcagc gtctgggcct tgggccccgt
     3301 gaccgcgtca tcgcccttgc cagcctgtcc ttcgaccttt ccgtgttcga ccttttcggc
     3361 gtcacggcag cgggaggcgc cgtcgtcatc cccgctcccg gacaggagag ggatcccgcg
     3421 gcctggtgcc gcctgatgcg ggaacagggc gtgaccgtct ggaacagcac cccttcgctc
     3481 atgcagctgc tgctcgacta tctggacgac caccccgagg acaggccgga acaactgcgc
     3541 ctggccctgc tcagtggcga ctggatcccc cttgccatgc cggaccgcat gcacgcactg
     3601 tggccggaca tgaccgttgc cgccctcgga ggagccaccg aagccgccat ctggtccaac
     3661 atccagatcg tggaccatat cccggcagaa tggcacagca tcccctacgg ccgtccgctg
     3721 gccaaccagg gatatcttgt cttcgaccag gacctgtgcc cctgcccgga tcttgtggcc
     3781 ggtgacctgt acatcaccgg ggcgggcctg gcccgcggct acctcaacga tccctccaaa
     3841 acggccgcgg cctttttccg ccatccccgc agcgggcagg ccctgtaccg cacgggagac
     3901 ctgggccgct actggcctga cggcactttg gaattcctcg gccgcaaaga cagccaggtc
     3961 aagatcaacg gtttccgtat cgagctgggc gaggtggaac gggccctgaa cgccctcccc
     4021 ggcgtgggca atgccgccgt catcgccctc aggagcgaca agggcgacag gctcgcct
//
