gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
650064839	415	17.58	57	386	61	378	5.0e-05	42.5	COG2814	Predicted arabinose efflux permease, MFS family	394
650064840	197	25.14	1	179	5	182	2.0e-12	65.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650064842	453	31.24	3	425	1	415	4.0e-65	242	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
650064843	211	22.28	4	194	3	199	5.0e-11	61.5	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
650064844	159	61.01	1	159	3	161	1.0e-66	245	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
650064848	559	37.37	1	462	28	505	4.0e-113	402	COG0513	Superfamily II DNA and RNA helicase	513
650064850	556	36.85	4	519	3	517	3.0e-118	419	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
650064851	105	35.58	1	104	4	107	5.0e-10	56.1	COG3937	Polyhydroxyalkanoate synthesis regulator phasin	108
650064856	486	56.18	4	476	16	492	0.0e+00	671	COG0753	Catalase	496
650064860	336	40.07	31	321	3	278	3.0e-70	259	COG1686	D-alanyl-D-alanine carboxypeptidase	389
650064861	231	45.45	4	231	3	227	4.0e-62	231	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650064862	367	27.84	20	367	1	336	9.0e-37	148	COG0642	Signal transduction histidine kinase	336
650064863	370	46.7	178	359	1	179	4.0e-40	159	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
650064864	316	47.65	1	314	1	311	2.0e-83	302	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650064868	517	21.85	34	402	2	379	2.0e-36	146	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650064871	297	35.35	2	295	1	295	7.0e-58	217	COG1597	Diacylglycerol kinase family enzyme	301
650064872	624	40.85	35	619	1	567	0.0e+00	520	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650064873	575	38.18	1	571	4	567	5.0e-126	445	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650064874	160	34.51	33	144	19	126	2.0e-12	65	COG1846	DNA-binding transcriptional regulator, MarR family	126
650064875	351	35.92	10	315	2	298	9.0e-72	264	COG1162	Putative ribosome biogenesis GTPase RsgA	301
650064876	762	24.03	182	761	7	636	5.0e-66	246	COG1199	Rad3-related DNA helicase	654
650064877	264	34.62	57	258	49	255	3.0e-36	145	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650064878	347	31.46	1	346	2	340	4.0e-56	212	COG0673	Predicted dehydrogenase	342
650064880	540	52.24	29	516	13	493	0.0e+00	640	COG0753	Catalase	496
650064881	296	33.44	1	296	1	295	1.0e-48	186	COG0583	DNA-binding transcriptional regulator, LysR family	297
650064882	123	40.71	9	121	9	121	5.0e-17	80.2	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
650064883	229	49.56	1	228	1	228	8.0e-60	223	COG1346	Putative effector of murein hydrolase	230
650064884	619	28.62	15	611	22	627	2.0e-79	290	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
650064886	409	38.35	1	396	40	429	9.0e-101	360	COG1253	Hemolysin or related protein, contains CBS domains	429
650064887	529	17.45	207	516	15	374	6.0e-12	66	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
650064888	640	36.64	162	636	3	473	4.0e-101	362	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650064891	462	67.53	1	461	1	462	0.0e+00	757	COG0114	Fumarate hydratase class II	462
650064892	342	28.71	47	340	54	345	1.0e-28	120	COG4427	Uncharacterized protein	350
650064893	598	37.44	5	594	6	573	0.0e+00	522	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
650064894	591	37.8	17	589	4	558	0.0e+00	498	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
650064895	338	44.31	1	334	4	342	3.0e-72	265	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
650064896	467	51.74	1	455	2	451	0.0e+00	492	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
650064897	192	30.57	2	191	1	187	1.0e-35	142	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
650064898	198	23.32	1	190	2	192	1.0e-11	63.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650064899	591	27.41	252	582	26	336	4.0e-38	153	COG0642	Signal transduction histidine kinase	336
650064900	238	38.72	4	236	2	229	1.0e-57	215	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650064901	409	37.21	4	386	10	390	2.0e-65	243	COG2311	Uncharacterized membrane protein YeiB	394
650064902	101	40	1	94	2	95	5.0e-13	66.1	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
650064905	113	26.61	5	110	18	125	5.0e-09	53.1	COG5649	Uncharacterized protein	132
650064906	132	29.32	5	132	2	132	1.0e-16	79.2	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
650064907	420	50	6	415	3	411	1.0e-119	423	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
650064908	143	41.18	1	117	1	114	3.0e-24	104	COG3795	Uncharacterized conserved protein	123
650064910	382	18.73	69	381	1	282	2.0e-08	53.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650064912	304	55.33	3	300	1	299	3.0e-112	397	COG0031	Cysteine synthase	300
650064913	283	26.01	30	252	17	217	8.0e-25	107	COG0095	Lipoate-protein ligase A	248
650064915	542	32.29	1	535	21	606	3.0e-97	349	COG3211	Secreted phosphatase, PhoX family	616
650064916	73	36.23	4	72	2	70	6.0e-12	62.3	COG1826	Sec-independent protein translocase protein TatA	94
650064917	230	33.47	1	230	17	255	3.0e-41	161	COG0805	Sec-independent protein secretion pathway component TatC	255
650064918	525	34.48	40	519	8	473	8.0e-77	281	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650064919	348	40.12	53	345	118	440	2.0e-68	252	COG3325	Chitinase, GH18 family	441
650064923	462	23.88	53	383	1	331	5.0e-30	125	COG3669	Alpha-L-fucosidase	430
650064924	535	19.04	1	451	1	412	3.0e-16	80.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650064925	302	31.76	12	301	8	281	1.0e-46	180	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650064926	323	48.04	18	323	4	309	2.0e-95	342	COG4209	ABC-type polysaccharide transport system, permease component	309
650064928	345	32.54	24	344	61	437	2.0e-61	229	COG3325	Chitinase, GH18 family	441
650064929	70	50.72	1	69	3	70	2.0e-13	67.1	COG2155	Uncharacterized membrane protein YuzA, DUF378 family	79
650064930	347	32.2	30	346	12	329	3.0e-51	195	COG2855	Uncharacterized membrane protein YadS	334
650064931	299	26.87	2	295	20	282	2.0e-22	99	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650064932	302	23.2	12	302	18	312	1.0e-20	93.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650064933	159	61.39	1	158	3	160	8.0e-66	242	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
650064934	653	42.01	13	650	9	585	0.0e+00	581	COG3533	Uncharacterized conserved protein, DUF1680 family	589
650064935	274	30.89	152	274	2	124	1.0e-18	87.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650064936	133	45.45	1	131	3	125	3.0e-35	140	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
650064938	246	29.71	8	244	3	229	5.0e-28	118	COG1011	FMN phosphatase YigB, HAD superfamily	229
650064939	294	20.95	51	254	47	233	3.0e-13	69.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
650064940	344	33.69	1	343	1	373	4.0e-69	255	COG3835	Sugar diacid utilization regulator	376
650064941	382	58.87	7	378	3	374	0.0e+00	479	COG1929	Glycerate kinase	378
650064942	431	26.83	11	431	8	442	2.0e-43	170	COG2610	H+/gluconate symporter or related permease	442
650064943	470	41.16	2	441	47	508	9.0e-99	354	COG4147	Na+(or H+)/acetate symporter ActP	529
650064947	99	29.41	1	99	1	102	9.0e-17	78.4	COG3162	Uncharacterized membrane protein, DUF485 family	102
650064948	265	36.15	4	263	2	242	4.0e-41	161	COG3279	DNA-binding response regulator, LytR/AlgR family	244
650064949	584	35.99	1	575	1	550	1.0e-116	413	COG3275	Sensor histidine kinase, LytS/YehU family	557
650064950	151	33.8	1	141	2	143	2.0e-21	94.9	COG3610	Uncharacterized membrane protein YjjB, DUF3815 family	156
650064951	327	36.89	1	321	1	314	2.0e-61	229	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650064952	433	45.52	1	430	1	429	2.0e-125	443	COG0172	Seryl-tRNA synthetase	429
650064953	279	28.4	30	274	8	261	1.0e-39	156	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650064954	250	41.5	2	247	1	250	3.0e-53	201	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650064955	143	31.75	2	126	1	126	1.0e-12	65.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
650064958	747	51.84	14	744	1	709	0.0e+00	827	COG2217	Cation transport ATPase	713
650064960	66	44.12	1	66	1	68	4.0e-09	53.1	COG2608	Copper chaperone CopZ	71
650064961	107	41.57	19	106	1	89	9.0e-18	81.8	COG1937	DNA-binding transcriptional regulator, FrmR family	89
650064962	713	54.69	21	713	6	682	0.0e+00	900	COG3661	Alpha-glucuronidase	684
650064963	338	39.4	34	333	51	339	7.0e-75	274	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
650064964	311	30.64	20	310	8	281	3.0e-45	175	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650064965	346	54.76	53	346	18	309	1.0e-104	373	COG4209	ABC-type polysaccharide transport system, permease component	309
650064966	562	21.54	3	387	2	346	8.0e-13	69.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650064967	593	24.24	79	573	3	447	2.0e-50	193	COG2972	Sensor histidine kinase YesM	456
650064968	531	29.43	1	520	1	474	5.0e-67	249	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650064969	467	46.64	6	466	4	463	0.0e+00	557	COG1904	Glucuronate isomerase	463
650064970	225	31.42	1	225	6	230	2.0e-36	145	COG1802	DNA-binding transcriptional regulator, GntR family	230
650064971	365	50.97	1	351	1	357	0.0e+00	470	COG1312	D-mannonate dehydratase	362
650064972	313	31.52	36	307	2	250	6.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650064973	438	46.49	4	433	3	441	0.0e+00	489	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
650064974	327	30.94	1	301	4	290	8.0e-30	124	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
650064976	358	31.72	39	345	1	284	1.0e-56	213	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
650064977	296	33.44	1	296	1	289	3.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
650064978	272	25.66	53	268	50	268	3.0e-17	82.7	COG3393	Predicted acetyltransferase, GNAT family	268
650064979	178	25.95	20	174	1	142	7.0e-14	70.4	COG5628	Predicted acetyltransferase	143
650064984	257	44.18	6	254	4	251	2.0e-60	226	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650064985	283	25.36	147	281	3	139	1.0e-04	41	COG2510	Uncharacterized membrane protein	140
650064986	176	25.5	1	169	3	199	3.0e-22	98.4	COG1335	Nicotinamidase-related amidase	205
650064987	159	28.1	23	140	3	123	2.0e-12	65.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
650064988	297	32.42	10	296	8	281	1.0e-44	173	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650064989	311	42.19	11	311	9	309	4.0e-81	294	COG4209	ABC-type polysaccharide transport system, permease component	309
650064990	529	24.1	4	385	1	349	2.0e-14	74.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650064992	364	30.9	30	364	1	332	9.0e-47	181	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650064993	730	34.83	1	727	38	758	0.0e+00	606	COG3537	Putative alpha-1,2-mannosidase	768
650065001	187	31.64	10	184	6	182	2.0e-27	115	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065006	340	28.14	8	171	9	175	7.0e-22	98.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065007	327	52.55	1	306	5	314	2.0e-98	352	COG0180	Tryptophanyl-tRNA synthetase	314
650065008	349	34.57	5	323	2	304	2.0e-51	196	COG0492	Thioredoxin reductase	305
650065009	334	52.34	47	302	2	257	3.0e-93	335	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
650065010	315	24.62	1	315	1	315	4.0e-34	138	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650065014	336	40.61	8	336	2	330	3.0e-56	212	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
650065015	522	43.65	8	508	6	508	0.0e+00	496	COG1292	Choline-glycine betaine transporter	537
650065016	325	33.09	5	139	1	124	8.0e-07	48.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650065017	172	47.37	1	145	1	151	1.0e-45	175	COG0242	Peptide deformylase	168
650065018	80	29.49	1	77	2	71	3.0e-05	40.2	COG3655	DNA-binding transcriptional regulator, XRE family	73
650065019	214	30.66	1	212	1	199	2.0e-31	128	COG3764	Sortase (surface protein transpeptidase)	210
650065021	317	27.81	2	302	1	292	3.0e-05	43.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
650065023	229	34.53	3	221	2	223	2.0e-49	189	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650065024	334	23.48	8	327	8	332	2.0e-25	109	COG0642	Signal transduction histidine kinase	336
650065025	253	47.51	3	222	1	221	6.0e-75	273	COG1136	ABC-type lipoprotein export system, ATPase component	226
650065027	161	19.4	27	152	23	150	3.0e-03	35	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650065030	255	25.19	3	249	6	261	5.0e-27	114	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
650065031	232	19.68	33	218	25	212	9.0e-16	77.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650065032	312	34.16	32	293	23	303	1.0e-41	164	COG2367	Beta-lactamase class A	329
650065034	353	27.83	25	338	13	336	7.0e-42	164	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650065035	169	31.9	5	167	1	149	2.0e-22	98.6	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
650065036	125	41.76	22	110	19	109	3.0e-08	51	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650065040	404	42.6	19	401	10	394	1.0e-68	253	COG2814	Predicted arabinose efflux permease, MFS family	394
650065041	163	46.67	12	161	1	149	7.0e-33	133	COG0782	Transcription elongation factor, GreA/GreB family	151
650065042	389	31.98	2	381	17	455	1.0e-76	280	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
650065043	146	49.64	4	142	2	140	8.0e-39	152	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
650065044	689	24.29	6	496	2	443	8.0e-43	169	COG3711	Transcriptional antiterminator	491
650065045	477	67.95	10	476	3	467	0.0e+00	662	COG2213	Phosphotransferase system, mannitol-specific IIBC component	472
650065049	295	24.32	6	289	8	254	5.0e-21	95.3	COG0584	Glycerophosphoryl diester phosphodiesterase	257
650065051	425	34.55	245	424	63	253	8.0e-29	121	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650065053	237	23.14	1	237	5	255	8.0e-04	37.7	COG0730	Uncharacterized membrane protein YfcA	258
650065054	113	78.57	2	113	1	112	4.0e-46	176	COG2824	Uncharacterized Zn-ribbon-containing protein	112
650065055	338	21.75	1	311	1	314	1.0e-26	114	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650065056	166	46.67	1	164	1	163	1.0e-45	175	COG4297	Uncharacterized protein YjlB	163
650065058	304	41.84	11	301	10	302	1.0e-58	220	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
650065062	264	24.54	14	264	18	280	4.0e-26	111	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650065063	363	25.57	4	350	2	323	4.0e-28	119	COG3274	Surface polysaccharide O-acyltransferase, integral membrane enzyme	332
650065064	386	31.56	85	378	117	436	6.0e-49	188	COG3325	Chitinase, GH18 family	441
650065066	492	42.34	5	492	1	488	0.0e+00	576	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
650065067	246	43.35	22	245	44	276	5.0e-50	191	COG4760	Uncharacterized membrane protein, YccA/Bax inhibitor family	276
650065071	481	34.02	1	445	26	513	8.0e-110	391	COG0513	Superfamily II DNA and RNA helicase	513
650065072	501	35.44	5	475	1	429	4.0e-107	381	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
650065074	362	28.46	95	361	81	344	3.0e-33	136	COG4194	Uncharacterized membrane protein	350
650065077	262	31.73	3	242	13	245	1.0e-31	130	COG2746	Aminoglycoside N3'-acetyltransferase	251
650065078	433	22.3	1	425	5	424	3.0e-38	153	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650065080	296	26.39	115	258	3	143	6.0e-08	51.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
650065090	146	29.6	23	144	23	146	2.0e-11	61.6	COG0071	Molecular chaperone IbpA, HSP20 family	146
650065097	214	33.33	15	213	11	183	8.0e-24	103	COG0693	Putative intracellular protease/amidase	188
650065101	142	31.25	14	140	1	126	1.0e-08	52.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
650065102	436	26.48	14	429	12	392	7.0e-29	122	COG1228	Imidazolonepropionase or related amidohydrolase	406
650065105	517	26.84	4	233	1	221	2.0e-26	114	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650065113	131	20.91	25	130	4	110	2.0e-05	41.9	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
650065114	245	24.49	20	208	17	210	5.0e-11	61.5	COG3279	DNA-binding response regulator, LytR/AlgR family	244
650065115	181	19.14	7	166	4	158	1.0e-09	56	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
650065123	312	25.57	13	307	1	295	1.0e-23	104	COG4974	Site-specific recombinase XerD	300
650065127	485	30	56	401	3	322	2.0e-51	197	COG0270	Site-specific DNA-cytosine methylase	328
650065132	146	37.5	1	125	1	127	2.0e-24	105	COG3727	G:T-mismatch repair DNA endonuclease, very short patch repair protein	150
650065134	127	34.23	16	125	3	111	4.0e-19	87.3	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
650065141	192	27.78	3	164	14	172	9.0e-13	67	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650065145	148	26.81	1	136	1	134	6.0e-09	53.3	COG3153	Predicted N-acetyltransferase YhbS	171
650065147	456	39.61	152	456	58	344	5.0e-57	215	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
650065149	267	34.66	1	233	2	252	3.0e-38	152	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
650065150	249	20.65	1	226	1	241	2.0e-12	66.5	COG4853	Two-component signal transduction system YycFG, regulatory protein YycI	264
650065151	425	22.09	2	415	3	422	1.0e-28	120	COG4863	Two-component signal transduction system YycFG, regulatory protein YycH	439
650065152	609	51.33	151	600	1	447	8.0e-127	447	COG5002	Signal transduction histidine kinase	459
650065153	243	47.64	5	236	3	226	5.0e-65	241	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650065155	524	31.29	258	524	3	261	1.0e-34	141	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
650065157	225	45.41	3	224	2	229	1.0e-57	215	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650065158	460	33.87	152	458	28	328	1.0e-49	191	COG0642	Signal transduction histidine kinase	336
650065160	232	46.19	6	227	2	224	6.0e-72	263	COG1136	ABC-type lipoprotein export system, ATPase component	226
650065161	429	58.39	1	421	1	423	0.0e+00	634	COG0104	Adenylosuccinate synthase	430
650065162	440	52	8	431	14	435	0.0e+00	501	COG0305	Replicative DNA helicase	435
650065163	147	55.78	1	147	1	147	8.0e-39	152	COG0359	Ribosomal protein L9	148
650065164	665	46.21	1	655	1	647	0.0e+00	667	COG3887	c-di-AMP phosphodiesterase, consists of a GGDEF-like and DHH domains	655
650065165	305	19.66	15	303	20	312	7.0e-11	61.9	COG4241	Uncharacterized conserved protein YybS, DUF2232 family	314
650065167	147	24.58	10	126	6	117	2.0e-06	44.8	COG0517	CBS domain	117
650065168	328	25.16	1	311	1	295	3.0e-42	165	COG1316	Anionic cell wall polymer biosynthesis enzyme,  LytR-Cps2A-Psr (LCP) family	307
650065169	330	43.05	1	294	2	279	8.0e-72	264	COG1686	D-alanyl-D-alanine carboxypeptidase	389
650065170	321	55.13	2	313	1	266	3.0e-108	385	COG4608	ABC-type oligopeptide transport system, ATPase component	309
650065171	325	59.56	5	319	1	316	2.0e-130	458	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650065172	307	47.59	19	307	7	288	1.0e-72	266	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650065173	320	43.89	1	319	1	315	5.0e-87	314	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650065177	90	62.67	11	85	1	75	1.0e-20	91.4	COG0238	Ribosomal protein S18	75
650065178	165	44.77	1	165	2	167	5.0e-32	130	COG0629	Single-stranded DNA-binding protein	167
650065199	70	31.88	1	69	2	70	3.0e-09	53.7	COG3655	DNA-binding transcriptional regulator, XRE family	73
650065200	303	27.42	16	300	6	300	2.0e-31	130	COG4974	Site-specific recombinase XerD	300
650065202	83	41.18	1	67	2	69	1.0e-08	51.5	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
650065205	348	25.81	32	336	12	299	2.0e-43	169	COG4974	Site-specific recombinase XerD	300
650065207	73	63.16	4	60	3	59	2.0e-18	84.2	COG4481	Uncharacterized protein	60
650065208	296	30.68	40	286	37	283	2.0e-25	109	COG0668	Small-conductance mechanosensitive channel	316
650065213	382	37.05	3	380	22	402	1.0e-85	310	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
650065214	279	36.9	24	274	4	240	2.0e-35	143	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
650065215	253	47.43	1	251	1	252	4.0e-63	234	COG1192	Cellulose biosynthesis protein BcsQ	259
650065216	272	45.88	18	210	1	191	8.0e-33	134	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
650065217	240	43.96	14	220	11	213	5.0e-60	224	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
650065218	628	63.43	4	620	1	617	0.0e+00	988	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
650065219	458	52.29	1	458	2	454	0.0e+00	530	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
650065220	260	33.59	3	258	1	208	2.0e-47	182	COG1847	Predicted RNA-binding protein Jag, conains KH and R3H domains	208
650065222	128	37.39	15	128	3	116	8.0e-18	82.6	COG0594	RNase P protein component	117
650065224	299	60.67	1	299	1	300	9.0e-122	430	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
650065225	225	26.11	1	225	5	225	2.0e-28	119	COG1802	DNA-binding transcriptional regulator, GntR family	230
650065226	453	48.09	11	453	1	442	9.0e-91	327	COG2610	H+/gluconate symporter or related permease	442
650065227	515	36.74	2	505	1	501	2.0e-121	429	COG1070	Sugar (pentulose or hexulose) kinase	502
650065229	448	48.73	9	441	1	407	0.0e+00	483	COG0593	Chromosomal replication initiation ATPase DnaA	408
650065230	380	34.56	1	378	1	364	4.0e-69	255	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
650065231	71	42.25	1	71	2	72	2.0e-15	74.1	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
650065232	370	46.34	1	368	1	361	5.0e-111	394	COG1195	Recombinational DNA repair ATPase RecF	363
650065234	634	65.99	1	634	1	635	0.0e+00	1014	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
650065235	832	59.41	1	808	1	804	0.0e+00	1052	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
650065241	217	27.01	31	204	1	163	4.0e-07	48.4	COG2801	Transposase InsO and inactivated derivatives	232
650065244	555	33.93	5	554	6	545	5.0e-102	365	COG1982	Arginine/lysine/ornithine decarboxylase	557
650065245	214	43.69	5	210	2	205	2.0e-57	215	COG0125	Thymidylate kinase	208
650065246	109	69.72	1	109	1	109	6.0e-42	162	COG3870	Uncharacterized protein YaaQ	109
650065247	147	27.2	21	145	25	149	7.0e-20	90	COG1728	Uncharacterized protein YaaR, TM1646/DUF327 family	151
650065249	266	54.34	1	264	1	264	3.0e-77	281	COG1774	Cell fate regulator YaaT, PSP1 superfamily (controls sporulation, competence, biofilm development)	265
650065250	123	50	1	123	1	113	3.0e-24	103	COG4467	Regulator of replication initiation timing	114
650065251	255	44.8	1	249	2	245	3.0e-72	265	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
650065252	297	50	18	294	5	272	7.0e-90	324	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
650065255	429	39.66	6	411	1	404	3.0e-96	345	COG1078	HD superfamily phosphohydrolase	421
650065256	254	58.2	1	254	2	256	1.0e-93	336	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
650065258	205	46.77	17	135	2	125	4.0e-27	115	COG1658	5S rRNA maturation endonuclease (Ribonuclease M5), contains TOPRIM domain	127
650065259	294	51.67	21	289	1	255	4.0e-84	304	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
650065261	91	66.67	4	75	5	76	2.0e-24	103	COG4466	Uncharacterized protein Veg	80
650065263	284	45.45	1	283	2	284	1.0e-85	309	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
650065264	275	31.87	81	260	1	179	1.0e-34	140	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
650065265	94	73.91	1	92	1	92	2.0e-35	140	COG2088	DNA-binding protein SpoVG, cell septation regulator	95
650065266	462	55.12	1	455	1	459	0.0e+00	626	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
650065267	317	61.34	5	315	2	314	4.0e-125	441	COG0462	Phosphoribosylpyrophosphate synthetase	314
650065269	187	53.23	1	185	2	187	1.0e-69	255	COG0193	Peptidyl-tRNA hydrolase	190
650065271	1175	45.8	23	1158	6	1132	0.0e+00	1274	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
650065272	361	21.24	8	313	1	295	8.0e-07	48.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
650065273	180	45.45	1	76	1	77	1.0e-11	62.7	COG2002	Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module	89
650065274	560	25.81	8	528	6	479	3.0e-24	107	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
650065275	504	47.87	1	493	1	484	0.0e+00	514	COG3956	Uncharacterized conserved protein YabN, contains tetrapyrrole methylase and MazG-like pyrophosphatase domain	488
650065277	92	46.15	1	91	9	99	5.0e-21	92.7	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
650065280	116	19.39	13	106	11	108	8.0e-06	42.6	COG2919	Cell division protein FtsB	117
650065281	163	45	1	160	1	129	3.0e-35	141	COG1098	Predicted RNA-binding protein, contains ribosomal protein S1 (RPS1) domain	129
650065282	836	21.34	419	813	1	367	5.0e-34	140	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
650065285	476	34.25	5	294	2	287	1.0e-45	178	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
650065287	179	65.34	1	176	3	178	6.0e-69	253	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
650065288	689	57.4	10	607	2	589	0.0e+00	727	COG0465	ATP-dependent Zn proteases	596
650065289	312	53.92	11	312	18	323	2.0e-114	405	COG0379	Quinolinate synthase	324
650065290	538	46	19	528	8	513	0.0e+00	560	COG0029	Aspartate oxidase	518
650065291	291	56.73	10	284	6	279	2.0e-98	352	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
650065292	254	47.06	1	254	1	251	1.0e-70	259	COG1521	Pantothenate kinase type III	251
650065293	294	46.45	6	285	5	283	5.0e-84	304	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
650065294	311	18.42	46	306	51	303	4.0e-09	55.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
650065295	311	57.57	4	305	1	300	4.0e-112	397	COG0031	Cysteine synthase	300
650065297	193	67.38	1	186	3	189	3.0e-85	307	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
650065298	295	38.64	1	291	1	280	2.0e-51	196	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
650065299	286	46.24	18	279	2	267	6.0e-78	284	COG0294	Dihydropteroate synthase	274
650065300	120	45	1	120	2	121	4.0e-30	123	COG1539	Dihydroneopterin aldolase	121
650065301	182	48.73	12	169	4	157	2.0e-45	175	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
650065303	343	47.4	3	326	1	323	4.0e-90	324	COG0042	tRNA-dihydrouridine synthase	323
650065304	158	48	8	157	1	149	7.0e-35	140	COG0782	Transcription elongation factor, GreA/GreB family	151
650065305	503	61.95	5	503	1	502	0.0e+00	749	COG1190	Lysyl-tRNA synthetase (class II)	502
650065307	485	31.19	258	475	1	170	7.0e-40	158	COG0516	IMP dehydrogenase/GMP reductase	170
650065308	472	34.09	68	465	25	389	4.0e-76	279	COG1686	D-alanyl-D-alanine carboxypeptidase	389
650065309	293	73.04	1	293	4	296	0.0e+00	497	COG0214	Pyridoxal biosynthesis lyase PdxS	296
650065310	195	57.81	1	188	1	192	2.0e-72	265	COG0311	Glutamine amidotransferase PdxT (pyridoxal biosynthesis)	194
650065311	427	62.79	1	427	1	429	0.0e+00	595	COG0172	Seryl-tRNA synthetase	429
650065317	163	58.22	15	159	7	152	3.0e-50	191	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
650065318	233	40.74	1	228	3	245	3.0e-58	218	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
650065319	273	36.72	1	256	1	243	3.0e-53	202	COG1360	Flagellar motor protein MotB	244
650065320	266	44.19	1	258	1	258	6.0e-66	244	COG1291	Flagellar motor component MotA	266
650065322	103	35.79	4	97	7	101	8.0e-18	81.9	COG2154	Pterin-4a-carbinolamine dehydratase	101
650065323	118	25.62	1	117	14	127	4.0e-07	46.9	COG2010	Cytochrome c, mono- and diheme variants	150
650065330	748	36.08	21	737	4	708	0.0e+00	618	COG2217	Cation transport ATPase	713
650065331	127	38	27	126	2	101	1.0e-11	61.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650065334	686	41.97	4	633	3	631	0.0e+00	559	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
650065335	289	38.16	1	289	1	303	3.0e-61	228	COG0010	Arginase family enzyme	305
650065337	690	23.64	4	362	2	362	2.0e-39	157	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650065339	285	28.52	1	281	1	269	3.0e-36	146	COG0388	Predicted amidohydrolase	274
650065340	223	15.71	17	207	10	163	5.0e-06	44.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650065342	141	28.47	1	140	3	143	4.0e-14	70.8	COG4506	Uncharacterized beta-barrel protein YwiB, DUF1934 family	143
650065343	559	43.15	3	559	1	577	0.0e+00	570	COG0018	Arginyl-tRNA synthetase	577
650065345	188	35.93	12	175	9	175	5.0e-09	54.2	COG3343	DNA-directed RNA polymerase, delta subunit	175
650065346	533	67.8	2	532	1	530	0.0e+00	931	COG0504	CTP synthase (UTP-ammonia lyase)	533
650065348	284	55.9	1	284	1	286	2.0e-106	379	COG0191	Fructose/tagatose bisphosphate aldolase	286
650065349	419	54.27	1	418	1	421	0.0e+00	558	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
650065350	445	63.86	2	410	3	417	0.0e+00	651	COG1158	Transcription termination factor Rho	422
650065351	425	22.32	184	403	43	245	5.0e-09	56.1	COG1180	Pyruvate-formate lyase-activating enzyme	260
650065352	65	48.53	1	64	1	68	8.0e-19	85.3	COG0254	Ribosomal protein L31	75
650065355	573	38.76	1	494	1	485	4.0e-124	438	COG2812	DNA polymerase III, gamma/tau subunits	515
650065356	103	49.51	1	103	4	105	4.0e-23	99.5	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
650065357	199	58.08	1	198	1	198	8.0e-85	306	COG0353	Recombinational DNA repair protein RecR	198
650065370	374	53.42	1	365	1	338	7.0e-124	437	COG3839	ABC-type sugar transport system, ATPase component	338
650065372	312	56.91	3	306	1	304	6.0e-103	367	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
650065373	377	37.79	6	301	11	286	2.0e-64	239	COG0682	Prolipoprotein diacylglyceryltransferase	287
650065374	216	33.94	1	214	3	220	1.0e-41	163	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
650065375	168	32.89	14	156	22	173	6.0e-18	83.8	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
650065376	408	18.51	8	354	12	345	3.0e-09	56.3	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
650065377	397	35.93	7	363	3	356	3.0e-70	259	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
650065378	215	43.38	5	212	3	219	2.0e-56	212	COG0040	ATP phosphoribosyltransferase	290
650065379	201	58.46	7	201	2	195	8.0e-79	286	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
650065380	203	58.5	1	199	2	200	2.0e-79	288	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
650065381	243	55.51	4	239	2	235	2.0e-77	282	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
650065382	252	67.32	1	252	1	254	1.0e-111	396	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
650065383	234	52.73	8	116	1	110	2.0e-42	166	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
650065383	234	57.61	141	232	1	92	2.0e-29	122	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
650065384	279	23.41	1	251	1	212	6.0e-23	101	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
650065385	316	49.84	1	311	1	313	2.0e-100	359	COG0462	Phosphoribosylpyrophosphate synthetase	314
650065386	578	20.59	25	223	37	238	1.0e-05	45.4	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
650065387	317	52.46	1	304	3	301	5.0e-92	331	COG0492	Thioredoxin reductase	305
650065388	162	30.94	24	162	1	139	2.0e-14	71.5	COG5577	Spore coat protein CotF	145
650065389	150	23.08	1	121	1	124	1.0e-05	42.9	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
650065390	272	28.57	4	86	1	84	4.0e-10	58.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
650065391	259	34.47	1	254	1	262	4.0e-38	151	COG3231	Aminoglycoside phosphotransferase	266
650065392	164	25.49	6	152	12	158	6.0e-11	60.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650065393	192	20.44	1	179	2	178	6.0e-12	64.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650065395	473	52.86	93	471	30	411	0.0e+00	475	COG0281	Malic enzyme	432
650065396	508	55.49	1	507	1	502	0.0e+00	530	COG3333	TctA family transporter	504
650065398	335	38.04	10	335	2	319	2.0e-67	249	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650065399	536	41.1	1	526	8	533	0.0e+00	471	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
650065400	231	43.11	2	226	1	220	9.0e-61	226	COG4565	Response regulator of citrate/malate metabolism	224
650065402	368	21.54	13	202	2	173	5.0e-08	52.2	COG4767	Glycopeptide antibiotics resistance protein	199
650065405	153	30.16	1	125	6	121	7.0e-12	63.5	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650065409	269	39.54	5	265	7	265	3.0e-40	158	COG2035	Uncharacterized membrane protein	276
650065410	189	22.62	3	170	9	174	9.0e-09	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650065419	122	33.9	1	118	2	118	4.0e-19	86.8	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
650065420	403	27.7	19	371	11	365	4.0e-44	172	COG4585	Signal transduction histidine kinase	365
650065421	248	18.03	18	245	51	282	1.0e-06	46.8	COG0842	ABC-type multidrug transport system, permease component	286
650065422	307	33.22	8	300	3	291	6.0e-57	214	COG1131	ABC-type multidrug transport system, ATPase component	293
650065423	316	40.58	6	315	8	307	6.0e-56	211	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
650065424	302	54.04	16	300	2	286	1.0e-115	409	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
650065425	326	45.4	6	311	5	318	2.0e-78	285	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
650065426	309	53.57	1	308	1	305	3.0e-94	338	COG1481	DNA-binding transcriptional regulator WhiA, involved in cell division	308
650065427	89	44.32	1	88	1	88	5.0e-24	102	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
650065428	226	45.37	3	222	2	226	3.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650065429	358	35.53	54	354	38	332	2.0e-44	173	COG0642	Signal transduction histidine kinase	336
650065430	242	67.36	4	242	3	240	8.0e-110	389	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650065431	253	35.86	18	253	11	242	3.0e-35	141	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
650065432	323	48.86	1	323	3	352	7.0e-111	393	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
650065433	282	45.29	1	274	6	281	3.0e-66	245	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
650065434	230	47.12	1	207	5	212	1.0e-56	212	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
650065436	350	40.33	1	350	2	363	2.0e-75	276	COG0687	Spermidine/putrescine-binding periplasmic protein	363
650065438	198	71.35	1	192	1	192	2.0e-83	301	COG0740	ATP-dependent protease ClpP, protease subunit	200
650065440	347	26.9	11	344	3	321	6.0e-54	205	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
650065441	334	67.07	1	332	1	333	0.0e+00	488	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
650065442	393	59.05	1	393	2	393	0.0e+00	531	COG0126	3-phosphoglycerate kinase	395
650065443	250	55.16	1	250	1	248	3.0e-83	301	COG0149	Triosephosphate isomerase	251
650065444	514	59.88	2	510	1	507	0.0e+00	731	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
650065445	429	70.66	1	426	1	423	0.0e+00	684	COG0148	Enolase	423
650065449	374	40.11	10	364	2	341	4.0e-89	321	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650065450	103	32.04	1	103	13	98	5.0e-10	56.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650065451	310	45.02	18	302	15	302	3.0e-74	272	COG4189	Predicted transcriptional regulator	308
650065457	739	28.78	2	660	1	652	6.0e-112	398	COG1201	Lhr-like helicase	814
650065459	339	36.06	4	328	1	328	1.0e-76	279	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650065460	329	42.35	20	325	2	306	4.0e-79	288	COG4209	ABC-type polysaccharide transport system, permease component	309
650065461	294	28.92	13	293	8	281	3.0e-46	179	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065462	548	19.08	63	399	27	349	3.0e-13	70.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065463	448	23.88	36	442	36	425	5.0e-55	208	COG5520	O-Glycosyl hydrolase	433
650065469	546	40.89	1	543	4	558	0.0e+00	546	COG0143	Methionyl-tRNA synthetase	558
650065470	557	43.66	10	529	1	505	2.0e-111	397	COG0366	Glycosidase	505
650065471	266	21.15	3	261	31	279	2.0e-18	86.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650065474	254	37.8	1	253	1	253	7.0e-59	220	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650065476	539	22.16	5	539	5	539	2.0e-50	193	COG1178	ABC-type Fe3+ transport system, permease component	540
650065478	364	31.75	3	357	5	359	4.0e-84	305	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
650065479	272	23.23	3	256	1	217	2.0e-19	90.2	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
650065481	482	31.8	21	340	50	365	6.0e-47	182	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650065482	315	16.62	2	315	1	299	3.0e-19	89.4	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
650065487	205	36.06	4	202	3	207	1.0e-42	166	COG4832	Uncharacterized protein	207
650065488	262	24.23	3	261	67	310	1.0e-20	93.9	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650065489	214	22.28	13	205	6	193	4.0e-12	65.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650065490	192	36.02	1	182	14	198	2.0e-39	155	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
650065491	105	28.43	1	102	5	91	4.0e-07	46.5	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
650065493	241	42.08	3	241	1	232	4.0e-49	188	COG2025	Electron transfer flavoprotein, alpha subunit	313
650065494	255	45	1	255	1	260	8.0e-63	233	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
650065495	196	27.13	1	185	6	193	9.0e-12	63.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650065498	396	45.72	1	392	1	392	2.0e-87	316	COG0183	Acetyl-CoA acetyltransferase	392
650065499	559	41.36	24	556	12	529	0.0e+00	481	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650065501	149	29.63	16	148	2	136	1.0e-18	85.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
650065502	76	44	1	75	1	72	6.0e-06	42.5	COG1314	Preprotein translocase subunit SecG	86
650065503	891	46.98	1	711	4	706	0.0e+00	744	COG0557	Exoribonuclease R	706
650065504	159	51.95	3	156	1	153	3.0e-52	197	COG0691	tmRNA-binding protein	153
650065506	268	24	2	243	56	283	6.0e-19	88	COG4974	Site-specific recombinase XerD	300
650065512	592	21.53	18	571	16	620	1.0e-44	174	COG0210	Superfamily I DNA or RNA helicase	655
650065518	378	29.41	137	315	2	187	5.0e-23	102	COG2856	Zn-dependent peptidase ImmA, M78 family	213
650065526	301	36.96	1	293	1	292	1.0e-66	246	COG1131	ABC-type multidrug transport system, ATPase component	293
650065527	247	20.08	2	245	39	283	3.0e-04	39.1	COG0842	ABC-type multidrug transport system, permease component	286
650065528	390	24.04	19	379	14	364	1.0e-40	160	COG4585	Signal transduction histidine kinase	365
650065529	201	36.19	2	201	1	210	5.0e-45	174	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650065532	343	24.14	1	87	2	88	8.0e-06	44.9	COG4842	Uncharacterized conserved protein YukE	97
650065540	333	48.8	1	330	2	328	6.0e-101	360	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
650065541	431	28.14	1	426	1	413	3.0e-65	242	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
650065544	417	18.18	104	399	53	316	1.0e-18	88	COG0668	Small-conductance mechanosensitive channel	316
650065545	673	49.85	124	465	2	338	7.0e-99	355	COG1299	Phosphotransferase system, fructose-specific IIC component	343
650065547	161	25.62	1	157	14	173	1.0e-19	89.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065550	66	65.67	1	66	1	67	6.0e-21	92.5	COG1278	Cold shock protein, CspA family	67
650065553	148	33.6	22	145	22	144	2.0e-16	78.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
650065554	233	32	1	222	1	225	6.0e-19	88	COG1842	Phage shock protein A	225
650065556	266	21.97	9	266	11	269	2.0e-25	109	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
650065557	339	36.49	1	339	4	345	8.0e-101	360	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
650065560	370	36.96	1	361	1	334	3.0e-54	206	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
650065561	510	60.64	1	501	1	501	0.0e+00	689	COG3845	ABC-type uncharacterized transport system, ATPase component	501
650065562	351	43.86	7	345	18	354	3.0e-73	268	COG4603	ABC-type uncharacterized transport system, permease component	356
650065563	317	46.73	12	316	14	304	2.0e-63	236	COG1079	ABC-type uncharacterized transport system, permease component	304
650065564	2086	35.81	1134	1639	16	503	4.0e-84	307	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
650065568	289	39.17	166	285	7	126	4.0e-20	92.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650065569	439	33.81	2	437	3	464	4.0e-68	252	COG3119	Arylsulfatase A or related enzyme	475
650065572	1651	25.91	533	1199	35	640	7.0e-113	403	COG1523	Pullulanase/glycogen debranching enzyme	697
650065574	284	29.61	5	284	15	317	1.0e-35	143	COG0226	ABC-type phosphate transport system, periplasmic component	318
650065575	320	43	30	318	10	308	7.0e-65	240	COG0573	ABC-type phosphate transport system, permease component	310
650065576	302	41.28	21	299	11	291	7.0e-62	230	COG0581	ABC-type phosphate transport system, permease component	292
650065577	258	24.55	1	201	1	205	3.0e-09	55.7	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
650065578	269	24.22	25	267	6	247	5.0e-07	48.4	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
650065579	714	38.43	11	248	1	235	3.0e-54	207	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
650065581	280	28.73	1	268	6	276	2.0e-33	136	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
650065583	562	14.5	144	550	32	399	5.0e-07	49.9	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
650065584	379	27.86	1	377	3	385	1.0e-54	207	COG3853	Uncharacterized conserved protein YaaN involved in tellurite resistance	386
650065585	207	21.14	1	175	5	172	2.0e-07	49.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650065586	316	24.22	27	276	35	283	2.0e-26	113	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
650065591	116	41.9	1	105	3	107	3.0e-32	130	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650065593	341	24.83	47	341	1	297	2.0e-48	186	COG1533	DNA repair photolyase	297
650065594	336	38.02	2	333	1	329	9.0e-82	297	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650065595	776	39.11	10	762	6	753	0.0e+00	668	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
650065596	431	25.8	10	431	1	431	9.0e-42	164	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065597	309	37.63	12	304	3	295	1.0e-61	230	COG1175	ABC-type sugar transport system, permease component	295
650065598	279	41.16	4	275	3	279	2.0e-57	216	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065602	217	40.19	4	212	1	202	2.0e-45	175	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650065603	415	22.38	13	404	14	420	9.0e-29	121	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650065604	450	45.58	16	450	9	439	4.0e-99	355	COG0733	Na+-dependent transporter, SNF family	439
650065605	75	47.95	1	73	2	74	6.0e-14	68.8	COG4224	Uncharacterized protein YnzC, UPF0291/DUF896 family	77
650065606	177	30.29	4	167	1	175	2.0e-23	102	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065608	431	25.48	1	410	5	408	2.0e-39	157	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650065610	291	23.57	110	249	3	139	7.0e-07	48.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
650065611	299	27.33	1	168	15	182	2.0e-18	86.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065612	148	33.57	8	141	33	172	9.0e-22	96.4	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
650065614	177	31.1	1	162	15	177	3.0e-26	111	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065617	249	28.64	26	231	12	214	2.0e-32	132	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650065618	355	35.74	12	344	6	333	5.0e-81	294	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
650065619	126	31.75	1	125	8	131	3.0e-18	83.8	COG5341	Uncharacterized protein	132
650065620	181	38.85	11	165	7	161	2.0e-20	92.2	COG4769	Uncharacterized membrane protein	181
650065621	290	49.12	16	239	10	235	6.0e-62	231	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
650065622	287	41.74	1	242	2	235	4.0e-58	218	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
650065623	263	35.91	5	263	1	248	1.0e-29	123	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
650065626	334	31.85	1	333	1	318	1.0e-55	210	COG0142	Geranylgeranyl pyrophosphate synthase	322
650065628	624	37.5	1	412	3	405	3.0e-97	349	COG1252	NADH dehydrogenase, FAD-containing subunit	405
650065629	302	26.23	181	302	27	136	1.0e-06	47.4	COG4939	Major membrane immunogen, membrane-anchored lipoprotein	147
650065630	310	36.74	6	309	4	306	1.0e-61	230	COG0167	Dihydroorotate dehydrogenase	310
650065631	233	23.32	4	227	12	252	1.0e-25	110	COG0543	NAD(P)H-flavin reductase	252
650065632	178	38.62	1	175	1	188	9.0e-41	159	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
650065633	109	45	4	102	2	101	4.0e-17	79.9	COG1695	DNA-binding transcriptional regulator, PadR family	138
650065634	440	26.03	78	426	11	374	6.0e-30	125	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
650065635	436	23.35	75	422	11	374	3.0e-25	110	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
650065636	214	37.72	1	212	1	227	1.0e-53	202	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650065637	305	36.93	29	300	3	281	2.0e-50	193	COG1408	Predicted phosphohydrolase, MPP superfamily	284
650065638	344	55.99	2	310	1	263	1.0e-106	379	COG4608	ABC-type oligopeptide transport system, ATPase component	309
650065639	340	59.75	11	326	1	315	0.0e+00	469	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650065640	307	50.32	1	304	1	313	3.0e-91	328	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650065641	536	33.84	42	534	34	552	1.0e-92	334	COG0747	ABC-type transport system, periplasmic component	556
650065642	319	33.94	4	319	3	330	6.0e-67	247	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650065643	402	18.4	1	402	14	431	8.0e-23	101	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065644	291	36.86	1	291	3	294	6.0e-52	197	COG1175	ABC-type sugar transport system, permease component	295
650065645	278	37.01	2	278	7	281	4.0e-47	181	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065647	476	24.64	12	298	26	362	6.0e-31	128	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650065653	559	53.49	1	558	3	560	0.0e+00	689	COG2060	K+-transporting ATPase, A chain	560
650065654	677	67.85	5	676	4	678	0.0e+00	1021	COG2216	High-affinity K+ transport system, ATPase chain B	681
650065655	209	56.52	27	207	8	190	8.0e-65	240	COG2156	K+-transporting ATPase, c chain	190
650065656	211	58.03	3	195	10	201	2.0e-63	235	COG0572	Uridine kinase	218
650065658	331	44.41	1	314	1	315	2.0e-85	309	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650065663	213	27.75	44	207	7	179	3.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065669	845	24.08	354	843	2	427	1.0e-43	172	COG3664	Beta-xylosidase	428
650065670	444	20.11	52	388	39	397	1.0e-12	67.9	COG2211	Na+/melibiose symporter or related transporter	467
650065673	517	23.04	35	494	47	451	1.0e-42	168	COG2972	Sensor histidine kinase YesM	456
650065675	441	24.94	1	438	1	429	1.0e-34	141	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065676	291	34.25	1	291	2	292	7.0e-56	210	COG1175	ABC-type sugar transport system, permease component	295
650065677	289	38.66	24	288	13	281	2.0e-54	206	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065678	355	54.44	6	185	7	186	2.0e-61	229	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
650065680	276	25.98	142	268	1	127	1.0e-18	86.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650065681	257	23.44	4	251	1	270	3.0e-20	92.2	COG1082	Sugar phosphate isomerase/epimerase	274
650065682	339	35.17	1	339	1	340	6.0e-64	237	COG0673	Predicted dehydrogenase	342
650065685	438	21.41	1	426	1	422	9.0e-33	135	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065686	281	42.05	1	281	1	281	2.0e-62	232	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065687	304	37.98	12	294	8	290	2.0e-50	193	COG1175	ABC-type sugar transport system, permease component	295
650065696	320	24.45	19	284	30	288	4.0e-24	105	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
650065697	225	33.93	7	225	2	219	8.0e-40	157	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
650065698	761	37.5	3	755	11	766	0.0e+00	637	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
650065700	600	27.86	204	598	67	456	8.0e-41	162	COG2972	Sensor histidine kinase YesM	456
650065701	518	27.61	2	516	3	473	5.0e-59	222	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650065702	415	23.74	6	415	2	427	4.0e-29	122	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065703	314	38.18	21	314	1	291	5.0e-54	205	COG1175	ABC-type sugar transport system, permease component	295
650065704	274	35.97	3	273	5	281	1.0e-49	190	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065705	709	41.77	15	392	1	367	6.0e-79	289	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
650065706	690	28.7	1	651	10	628	2.0e-96	347	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
650065707	156	19.23	19	142	21	147	9.0e-05	39.6	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650065709	184	38.29	10	184	5	179	8.0e-44	169	COG1954	Glycerol-3-phosphate responsive antiterminator (mRNA-binding)	181
650065711	323	23.05	1	322	102	433	2.0e-33	136	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065712	289	45.17	1	289	7	295	5.0e-63	234	COG1175	ABC-type sugar transport system, permease component	295
650065713	286	36.33	13	286	7	281	2.0e-51	196	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065714	281	25.29	4	263	3	261	2.0e-39	156	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
650065715	220	32.71	1	194	23	236	3.0e-30	125	COG0584	Glycerophosphoryl diester phosphodiesterase	257
650065716	199	23.08	1	182	6	184	5.0e-09	54.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650065718	238	35.84	5	229	2	224	3.0e-40	158	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
650065719	440	25.7	11	420	16	438	2.0e-44	173	COG2211	Na+/melibiose symporter or related transporter	467
650065720	304	22.54	1	280	1	255	5.0e-17	81.9	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
650065722	455	27.66	124	447	5	328	2.0e-35	143	COG0642	Signal transduction histidine kinase	336
650065723	535	30.28	295	535	81	330	1.0e-31	131	COG0642	Signal transduction histidine kinase	336
650065724	540	37.43	1	537	1	532	0.0e+00	461	COG1283	Na+/phosphate symporter	533
650065727	338	19.75	29	320	3	310	6.0e-12	65.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650065728	360	22.78	24	336	8	288	2.0e-13	70.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650065729	227	31.82	1	215	33	249	7.0e-38	150	COG1760	L-serine deaminase	262
650065730	309	40.68	16	278	10	262	2.0e-58	219	COG1760	L-serine deaminase	262
650065734	321	50.49	13	321	1	309	2.0e-95	342	COG4209	ABC-type polysaccharide transport system, permease component	309
650065735	292	32.53	9	291	5	281	6.0e-47	181	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065736	746	42.34	634	744	12	122	8.0e-22	99.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650065737	340	23.97	1	318	1	336	2.0e-21	96.6	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650065738	407	19.72	59	404	21	348	4.0e-08	53.1	COG3405	Endo-1,4-beta-D-glucanase Y	360
650065739	799	29.43	51	568	33	516	4.0e-89	323	COG3507	Beta-xylosidase	549
650065740	208	27.57	1	208	2	207	1.0e-27	116	COG0778	Nitroreductase	207
650065745	216	43.48	9	214	12	217	1.0e-46	179	COG0765	ABC-type amino acid transport system, permease component	222
650065746	219	42.47	1	218	3	221	1.0e-51	196	COG0765	ABC-type amino acid transport system, permease component	222
650065747	269	39.03	7	265	1	264	3.0e-38	152	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650065748	249	63.33	8	247	2	240	1.0e-110	392	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650065749	393	18.25	1	360	9	358	2.0e-08	53.6	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
650065752	66	67.16	1	66	1	67	3.0e-22	96.7	COG1278	Cold shock protein, CspA family	67
650065755	293	26.69	3	292	1	281	7.0e-42	164	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065756	554	22.35	57	403	29	349	7.0e-15	75.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065762	464	30.61	10	449	18	455	6.0e-66	245	COG0534	Na+-driven multidrug efflux pump	455
650065763	180	28.9	4	169	3	175	2.0e-23	102	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065765	405	35.48	71	399	16	347	1.0e-63	237	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
650065767	346	37.46	5	342	1	333	8.0e-91	327	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650065768	437	24.6	1	434	1	431	1.0e-38	154	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065769	293	34.02	1	289	5	290	2.0e-51	196	COG1175	ABC-type sugar transport system, permease component	295
650065770	276	42.86	1	275	2	281	3.0e-59	221	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065771	413	21.14	1	401	3	342	2.0e-36	147	COG0673	Predicted dehydrogenase	342
650065774	245	26.53	1	239	1	234	2.0e-33	136	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
650065776	385	35.34	8	383	16	380	1.0e-66	247	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
650065777	666	31.73	4	666	1	619	4.0e-105	376	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
650065778	194	27.94	1	188	3	205	5.0e-18	84.6	COG0778	Nitroreductase	207
650065780	276	56.2	11	276	7	280	9.0e-105	373	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
650065783	135	22.86	3	125	1	138	4.0e-10	57.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650065784	353	40	1	350	3	309	2.0e-81	296	COG2152	Predicted glycosyl hydrolase, GH43/DUF377 family	314
650065786	546	35.56	12	518	1	501	4.0e-88	319	COG0366	Glycosidase	505
650065787	279	35.59	4	277	3	278	2.0e-48	186	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065788	293	39.25	1	291	3	295	2.0e-51	196	COG1175	ABC-type sugar transport system, permease component	295
650065789	439	23.82	5	439	3	430	1.0e-33	137	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065790	575	28.79	41	568	1	463	2.0e-91	330	COG1109	Phosphomannomutase	464
650065791	819	35.42	53	680	3	636	1.0e-109	391	COG0210	Superfamily I DNA or RNA helicase	655
650065793	166	29.27	5	164	16	179	4.0e-26	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065798	544	28.39	220	527	3	311	8.0e-43	168	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
650065801	67	46.38	1	67	1	69	4.0e-10	56.2	COG2608	Copper chaperone CopZ	71
650065802	246	35.92	1	187	2	207	4.0e-27	115	COG0778	Nitroreductase	207
650065803	772	40.59	669	768	21	121	2.0e-19	91.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650065805	307	48.49	9	307	11	309	6.0e-97	347	COG4209	ABC-type polysaccharide transport system, permease component	309
650065806	294	31.65	3	293	2	281	6.0e-49	188	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065807	517	22.32	14	446	4	416	8.0e-22	99	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065809	271	32.7	12	271	2	256	3.0e-40	158	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
650065810	279	50.39	23	276	1	247	1.0e-82	299	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650065811	251	37.3	2	251	6	257	8.0e-47	180	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650065812	97	31.25	2	96	1	96	9.0e-19	85.3	COG0011	Uncharacterized conserved protein YqgV, UPF0045/DUF77 family	100
650065813	343	27.1	38	341	22	327	2.0e-37	149	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650065814	143	22.46	20	142	1	138	5.0e-08	50.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650065815	509	45.98	315	487	1	173	1.0e-37	151	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
650065818	769	45.71	2	766	1	767	0.0e+00	827	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
650065819	216	31.16	4	216	2	212	7.0e-41	160	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
650065820	344	41.19	3	336	1	328	6.0e-91	328	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650065821	564	35.25	70	526	2	492	1.0e-74	274	COG0366	Glycosidase	505
650065822	224	41.85	5	224	3	227	1.0e-50	193	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650065823	449	25.71	144	447	20	326	2.0e-26	113	COG0642	Signal transduction histidine kinase	336
650065824	306	35.55	7	302	4	293	1.0e-69	256	COG1131	ABC-type multidrug transport system, ATPase component	293
650065825	238	25.42	2	237	1	234	8.0e-23	100	COG4200	Uncharacterized protein	239
650065826	244	24.58	8	241	5	239	2.0e-24	106	COG4200	Uncharacterized protein	239
650065827	279	16.29	1	279	3	342	2.0e-06	46.8	COG0673	Predicted dehydrogenase	342
650065828	360	29.64	1	354	1	342	1.0e-59	223	COG0673	Predicted dehydrogenase	342
650065829	315	37.74	203	308	15	120	3.0e-23	102	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650065831	249	23.08	1	248	10	280	2.0e-22	99.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650065832	669	37.42	5	308	2	308	1.0e-66	248	COG0826	Collagenase-like protease, PrtC family	347
650065833	432	36.66	11	430	18	447	3.0e-106	378	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
650065834	290	29.72	3	285	2	287	1.0e-32	133	COG0382	4-hydroxybenzoate polyprenyltransferase	289
650065835	582	29.59	131	544	1	493	2.0e-61	230	COG0366	Glycosidase	505
650065836	86	36.49	1	74	5	78	6.0e-15	72.6	COG1937	DNA-binding transcriptional regulator, FrmR family	89
650065837	337	56.59	2	334	7	340	1.0e-125	442	COG2130	NADPH-dependent curcumin reductase CurA	340
650065838	163	46.9	11	155	5	148	3.0e-28	118	COG4846	Membrane protein CcdC involved in cytochrome C biogenesis	163
650065839	163	23.68	1	148	6	157	2.0e-07	48.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650065840	239	25	1	227	4	225	8.0e-21	94.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650065842	183	30.9	5	172	3	180	6.0e-27	114	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065848	354	41.4	10	350	6	346	5.0e-81	294	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
650065850	359	65.92	5	358	4	347	0.0e+00	515	COG1613	ABC-type sulfate transport system, periplasmic component	348
650065851	282	56.88	14	282	6	274	5.0e-77	280	COG0555	ABC-type sulfate transport system, permease component	274
650065852	288	67.75	10	285	1	276	8.0e-109	386	COG4208	ABC-type sulfate transport system, permease component	287
650065853	73	34.09	8	51	7	50	5.0e-06	42.7	COG5583	Uncharacterized protein	54
650065855	327	19.03	84	326	19	282	3.0e-15	76.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650065856	250	30	5	113	1	108	4.0e-11	62.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
650065858	210	49.06	1	210	1	211	6.0e-62	230	COG2910	Putative NADH-flavin reductase	211
650065859	583	44.1	116	275	45	203	6.0e-35	142	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
650065859	583	46.86	314	583	23	277	2.0e-58	220	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
650065861	302	35.6	53	297	1	249	2.0e-52	199	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650065863	181	30.51	3	177	2	178	1.0e-23	102	COG0431	NAD(P)H-dependent FMN reductase	184
650065865	184	52.27	9	183	3	168	4.0e-51	194	COG3910	Predicted ATPase	233
650065867	135	30.61	21	118	15	112	2.0e-10	58.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
650065869	265	62.4	1	250	7	256	1.0e-90	326	COG3739	Uncharacterized membrane protein YoaT, DUF817 family	263
650065871	313	29.51	1	182	3	184	3.0e-26	112	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650065873	343	31.88	5	342	3	343	4.0e-72	265	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
650065874	777	34.01	53	776	11	654	0.0e+00	573	COG0209	Ribonucleotide reductase alpha subunit	696
650065875	101	50	1	100	2	100	4.0e-23	99.5	COG0011	Uncharacterized conserved protein YqgV, UPF0045/DUF77 family	100
650065878	243	38.46	1	182	42	231	1.0e-36	146	COG0860	N-acetylmuramoyl-L-alanine amidase	231
650065880	588	34.98	13	578	1	560	1.0e-100	361	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650065881	601	28.01	1	585	1	567	1.0e-81	297	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650065886	191	31.91	1	138	1	139	4.0e-16	78.1	COG4502	5'(3')-deoxyribonucleotidase	180
650065887	750	39.59	5	749	109	930	0.0e+00	770	COG0178	Excinuclease UvrABC ATPase subunit	935
650065888	558	42.78	9	532	1	505	5.0e-103	368	COG0366	Glycosidase	505
650065889	353	39.66	6	349	1	350	5.0e-80	291	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650065892	172	29.55	1	168	4	179	2.0e-18	85.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065902	255	33.07	1	249	2	255	7.0e-45	174	COG0805	Sec-independent protein secretion pathway component TatC	255
650065904	536	33.74	65	536	7	450	2.0e-84	307	COG1231	Monoamine oxidase	450
650065905	181	32.86	38	177	7	129	1.0e-16	79.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650065907	67	38.46	1	65	3	67	1.0e-07	48	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
650065909	386	18.75	21	347	57	400	5.0e-05	42.5	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
650065911	126	58.59	1	126	2	129	3.0e-37	147	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650065912	309	26.03	11	293	36	319	3.0e-29	122	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650065917	293	35.25	1	293	1	294	2.0e-52	199	COG1175	ABC-type sugar transport system, permease component	295
650065918	278	36.65	1	277	1	281	9.0e-51	193	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065919	429	24.83	2	429	1	432	8.0e-38	151	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065922	933	26.35	304	933	73	770	1.0e-65	245	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
650065925	292	37.32	75	282	33	241	4.0e-46	178	COG1876	LD-carboxypeptidase LdcB, LAS superfamily	241
650065930	365	25.52	103	365	2	284	1.0e-26	114	COG1408	Predicted phosphohydrolase, MPP superfamily	284
650065931	189	34.44	1	180	5	179	6.0e-33	133	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
650065932	375	46.84	14	355	10	356	8.0e-87	314	COG2233	Xanthine/uracil permease	451
650065936	112	44.66	10	112	1	103	2.0e-20	91.1	COG4818	Uncharacterized membrane protein	105
650065939	349	22.98	48	317	64	363	1.0e-26	113	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650065942	249	46.61	1	249	1	251	1.0e-78	286	COG0024	Methionine aminopeptidase	255
650065943	349	42.92	11	243	1	227	2.0e-56	212	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
650065944	577	55.01	12	576	2	565	0.0e+00	591	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
650065946	206	42.64	8	203	14	207	2.0e-41	162	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
650065947	109	26.74	24	108	17	102	3.0e-08	50.2	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
650065948	302	28.86	1	288	1	296	2.0e-43	170	COG3336	Cytochrome c oxidase assembly factor CtaG	299
650065949	154	36.57	6	139	44	177	2.0e-25	108	COG2322	Uncharacterized membrane protein YozB, DUF420 family	177
650065951	133	34.96	4	126	1	123	1.0e-23	102	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
650065952	300	29.31	5	285	4	286	6.0e-46	177	COG1131	ABC-type multidrug transport system, ATPase component	293
650065953	300	49.66	4	300	3	300	2.0e-94	339	COG4152	ABC-type uncharacterized transport system, ATPase component	300
650065954	434	27.29	1	423	1	399	4.0e-38	152	COG1668	ABC-type Na+ efflux pump, permease component	407
650065956	723	16.2	13	722	4	705	1.0e-09	58.6	COG5295	Autotransporter adhesin	715
650065957	325	37.2	14	322	23	314	1.0e-47	184	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
650065958	176	32.95	2	176	7	178	3.0e-23	101	COG2059	Chromate transport protein ChrA	195
650065959	215	35.15	20	181	9	173	4.0e-26	111	COG2059	Chromate transport protein ChrA	195
650065960	512	23.83	1	509	1	473	1.0e-51	197	COG3119	Arylsulfatase A or related enzyme	475
650065961	284	38.78	183	280	22	119	1.0e-21	97.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650065964	513	17.65	43	377	30	349	1.0e-13	71.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065965	320	43.09	17	320	6	309	6.0e-92	331	COG4209	ABC-type polysaccharide transport system, permease component	309
650065966	297	29.73	7	296	1	281	2.0e-46	179	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065967	677	27.96	207	670	50	501	7.0e-62	232	COG3534	Alpha-L-arabinofuranosidase	501
650065968	432	38.17	5	430	3	420	1.0e-101	363	COG1253	Hemolysin or related protein, contains CBS domains	429
650065969	355	41.33	5	349	3	339	1.0e-84	307	COG1253	Hemolysin or related protein, contains CBS domains	429
650065970	1040	35.15	50	923	7	808	0.0e+00	547	COG3250	Beta-galactosidase/beta-glucuronidase	808
650065971	197	19.79	1	192	6	194	5.0e-07	47.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650065972	259	25.53	1	256	2	281	2.0e-28	119	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650065973	398	25.25	1	394	2	392	1.0e-47	184	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650065975	257	40.86	3	95	1	93	6.0e-17	81.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
650065978	171	25.74	35	161	19	139	2.0e-03	36.1	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650065980	471	53.65	93	471	30	411	0.0e+00	482	COG0281	Malic enzyme	432
650065982	345	38.08	15	299	7	308	4.0e-61	228	COG3397	Predicted carbohydrate-binding protein, contains CBM5 and CBM33 domains	308
650065983	409	35.42	138	406	75	335	1.0e-45	177	COG0642	Signal transduction histidine kinase	336
650065984	230	38.12	1	202	1	201	9.0e-55	206	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650065985	262	43.92	1	238	90	338	4.0e-65	241	COG3839	ABC-type sugar transport system, ATPase component	338
650065986	292	42.71	1	292	1	294	1.0e-58	220	COG1175	ABC-type sugar transport system, permease component	295
650065987	277	38.79	1	277	1	281	3.0e-56	212	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065988	437	26.55	1	437	1	432	6.0e-43	168	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065989	255	33.73	11	251	6	257	1.0e-36	146	COG0584	Glycerophosphoryl diester phosphodiesterase	257
650065990	406	29.16	31	395	13	337	2.0e-55	209	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
650065993	237	27.65	1	149	13	182	1.0e-14	74	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650065994	406	26.8	1	390	2	404	3.0e-37	149	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650065995	288	37.24	1	288	5	294	1.0e-54	207	COG1175	ABC-type sugar transport system, permease component	295
650065996	272	32.61	2	272	7	281	5.0e-43	168	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650065997	332	33.53	1	327	4	340	2.0e-61	229	COG0673	Predicted dehydrogenase	342
650065998	331	32.66	1	329	1	342	3.0e-52	199	COG0673	Predicted dehydrogenase	342
650066001	280	46.07	1	280	1	269	4.0e-64	238	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
650066002	203	31.4	1	203	3	205	5.0e-32	131	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650066007	336	22.22	14	327	9	327	8.0e-28	117	COG0642	Signal transduction histidine kinase	336
650066008	233	39.13	3	229	2	229	8.0e-52	197	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650066011	497	34.36	173	493	20	328	3.0e-43	169	COG0642	Signal transduction histidine kinase	336
650066012	228	44.2	8	224	2	224	3.0e-57	214	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650066015	65	77.78	1	63	1	63	1.0e-20	90.8	COG4895	Uncharacterized protein YwbE	63
650066018	161	63.35	1	161	2	162	3.0e-61	227	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
650066021	193	29.95	7	189	1	187	6.0e-22	97.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650066022	251	27.42	3	250	5	248	7.0e-21	94.7	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
650066023	196	31.49	17	192	9	188	1.0e-14	73.4	COG4721	ABC-type thiamine/hydroxymethylpyrimidine transport system, permease component	192
650066025	293	32.42	78	293	1	212	5.0e-40	158	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
650066026	504	15.79	18	345	20	380	4.0e-14	73.3	COG2814	Predicted arabinose efflux permease, MFS family	394
650066028	563	16.89	54	392	27	374	8.0e-09	55.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066029	296	41.41	1	296	13	309	3.0e-89	322	COG4209	ABC-type polysaccharide transport system, permease component	309
650066030	292	31.86	3	291	2	281	3.0e-43	168	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066031	690	42.4	8	686	9	672	0.0e+00	618	COG1874	Beta-galactosidase GanA	673
650066032	350	39.27	5	324	2	346	2.0e-71	262	COG3867	Arabinogalactan endo-1,4-beta-galactosidase	403
650066033	155	30.48	38	142	19	123	1.0e-13	69.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
650066034	452	18.26	77	441	58	394	3.0e-09	56.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650066037	421	23.24	12	377	5	344	1.0e-11	64.9	COG4473	Predicted ABC-type exoprotein transport system, permease component	379
650066038	425	47.27	1	421	1	408	0.0e+00	485	COG2081	Predicted flavoprotein YhiN	408
650066041	269	39.16	17	269	3	256	4.0e-61	228	COG0171	NH3-dependent NAD+ synthetase	268
650066042	130	43.75	1	128	1	124	3.0e-27	114	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
650066043	380	42.4	4	377	5	340	1.0e-104	373	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
650066044	414	18.72	64	390	85	430	1.0e-05	44.4	COG2271	Sugar phosphate permease	448
650066045	202	63.9	1	202	2	202	7.0e-79	286	COG0605	Superoxide dismutase	204
650066047	188	50	1	165	1	166	2.0e-55	208	COG1136	ABC-type lipoprotein export system, ATPase component	226
650066049	442	22.02	11	440	22	406	6.0e-20	92.3	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
650066050	362	22.65	1	362	1	354	3.0e-19	89.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650066051	140	27.21	3	123	14	149	4.0e-08	50.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650066053	617	43.24	18	354	2	337	4.0e-92	332	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
650066055	197	58.7	14	196	10	193	3.0e-73	267	COG0302	GTP cyclohydrolase I	195
650066059	389	48.26	188	383	4	203	2.0e-67	250	COG0605	Superoxide dismutase	204
650066061	246	40.25	9	243	1	241	2.0e-46	179	COG1414	DNA-binding transcriptional regulator, IclR family	246
650066062	365	27.37	8	365	5	348	4.0e-36	145	COG4194	Uncharacterized membrane protein	350
650066063	132	40.16	3	124	2	123	5.0e-30	123	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
650066065	905	61.8	5	902	1	861	0.0e+00	1205	COG1048	Aconitase A	861
650066067	364	39.66	5	349	2	317	2.0e-85	309	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
650066069	336	36.2	1	332	25	346	2.0e-80	293	COG4294	UV DNA damage repair endonuclease	347
650066070	287	46.47	14	279	2	260	1.0e-65	243	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
650066073	420	19.68	42	288	10	208	5.0e-07	49.5	COG2755	Lysophospholipase L1 or related esterase	216
650066075	248	48.21	1	248	2	252	1.0e-78	285	COG0024	Methionine aminopeptidase	255
650066077	440	27.16	1	440	1	472	5.0e-54	205	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650066078	311	32.76	24	310	1	290	3.0e-50	192	COG1175	ABC-type sugar transport system, permease component	295
650066079	288	30.3	28	287	18	281	1.0e-42	166	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066080	482	21.35	1	451	1	425	3.0e-25	110	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066082	438	55.15	3	438	2	431	0.0e+00	589	COG0001	Glutamate-1-semialdehyde aminotransferase	432
650066083	352	32.98	2	283	1	261	3.0e-46	179	COG1316	Anionic cell wall polymer biosynthesis enzyme,  LytR-Cps2A-Psr (LCP) family	307
650066084	151	59.73	1	149	4	152	1.0e-58	218	COG1225	Peroxiredoxin	157
650066085	284	40.08	41	281	37	275	3.0e-47	182	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
650066086	435	32.92	40	277	19	254	4.0e-32	132	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650066087	156	23.33	31	150	27	145	6.0e-09	53.8	COG2427	Uncharacterized conserved protein YjgD, DUF1641 family	148
650066088	391	42.28	1	390	2	391	8.0e-104	370	COG1252	NADH dehydrogenase, FAD-containing subunit	405
650066090	515	23.74	1	514	1	475	1.0e-57	217	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650066091	440	23.87	10	435	7	433	3.0e-44	172	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066092	317	42.25	31	312	7	290	4.0e-65	241	COG1175	ABC-type sugar transport system, permease component	295
650066093	277	42.14	1	276	2	281	2.0e-61	229	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066094	513	25.73	1	505	1	471	6.0e-59	222	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650066095	614	23.71	113	594	17	456	5.0e-44	172	COG2972	Sensor histidine kinase YesM	456
650066096	510	26.9	3	506	2	471	2.0e-56	213	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650066097	533	19.95	39	439	41	430	6.0e-12	66.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066098	287	49.83	1	286	24	308	9.0e-90	323	COG4209	ABC-type polysaccharide transport system, permease component	309
650066099	319	32.34	22	318	2	281	7.0e-45	174	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066100	767	44.41	5	324	3	329	5.0e-74	272	COG0714	MoxR-like ATPase	329
650066102	512	67.72	197	512	1	315	0.0e+00	539	COG0519	GMP synthase, PP-ATPase domain/subunit	315
650066104	456	50.55	1	454	6	436	3.0e-92	332	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
650066106	301	29.57	1	300	1	297	9.0e-35	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
650066107	344	44.63	3	323	6	352	3.0e-98	352	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
650066108	354	32.65	70	351	1	290	1.0e-40	160	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
650066109	561	29.67	6	550	1	529	2.0e-62	234	COG1178	ABC-type Fe3+ transport system, permease component	540
650066110	438	27.49	2	436	1	425	6.0e-45	175	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
650066111	326	52.34	5	325	3	323	4.0e-109	388	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
650066112	447	20.22	3	446	1	432	6.0e-30	125	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066113	318	37.41	25	315	7	295	3.0e-53	202	COG1175	ABC-type sugar transport system, permease component	295
650066114	287	38.63	14	286	6	281	2.0e-58	219	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066115	573	31.12	200	573	97	455	3.0e-48	186	COG2972	Sensor histidine kinase YesM	456
650066116	447	22.82	32	433	23	425	9.0e-37	148	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066117	532	27.31	8	527	2	473	1.0e-59	224	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650066118	323	32.12	4	129	1	137	4.0e-08	52.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650066119	318	29.72	1	318	5	311	3.0e-39	155	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650066120	297	27.69	9	265	3	245	7.0e-22	98	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650066121	85	45.68	1	78	1	81	2.0e-05	41.2	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
650066122	244	23.35	16	211	15	210	3.0e-18	85.4	COG3884	Acyl-ACP thioesterase	250
650066123	232	39.39	2	228	1	229	1.0e-46	179	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650066124	326	26.09	17	326	13	327	2.0e-33	136	COG0642	Signal transduction histidine kinase	336
650066125	256	50	3	224	1	224	2.0e-75	275	COG1136	ABC-type lipoprotein export system, ATPase component	226
650066129	711	34.98	2	595	1	567	0.0e+00	497	COG0550	DNA topoisomerase IA	570
650066132	144	37.33	1	144	3	151	3.0e-18	84.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
650066133	161	67.7	1	161	1	159	3.0e-64	237	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
650066134	395	49.73	19	389	1	364	6.0e-129	454	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
650066135	431	50.46	1	431	1	438	0.0e+00	545	COG0015	Adenylosuccinate lyase	438
650066136	296	34.28	16	293	5	247	1.0e-51	196	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
650066137	81	56.25	1	80	1	80	5.0e-23	99.1	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
650066138	229	56.39	1	217	3	228	3.0e-90	324	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
650066139	747	51.14	9	740	7	743	0.0e+00	937	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
650066140	492	56.32	29	487	1	462	0.0e+00	647	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
650066141	346	61.95	1	339	2	339	0.0e+00	472	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
650066142	203	48.74	5	203	2	200	6.0e-72	263	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
650066143	515	62.93	3	515	2	515	0.0e+00	769	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
650066145	422	57.55	1	421	1	423	0.0e+00	552	COG0151	Phosphoribosylamine-glycine ligase	428
650066146	436	36.55	40	428	22	412	2.0e-75	276	COG2182	Maltose-binding periplasmic protein MalE	420
650066147	437	31.35	132	433	8	293	4.0e-51	195	COG1175	ABC-type sugar transport system, permease component	295
650066148	280	53.57	1	280	3	282	2.0e-80	292	COG3833	ABC-type maltose transport system, permease component	282
650066149	678	27.49	293	663	54	407	1.0e-35	145	COG0840	Methyl-accepting chemotaxis protein	408
650066150	713	25.79	43	450	2	416	7.0e-48	185	COG0366	Glycosidase	505
650066151	378	30.49	22	375	43	385	1.0e-36	147	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650066152	318	28.68	188	309	19	154	6.0e-05	41.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650066153	235	22.77	1	197	5	202	1.0e-19	90.1	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
650066154	199	48.48	15	179	18	182	2.0e-45	175	COG0400	Predicted esterase	207
650066155	315	37.93	24	312	3	290	6.0e-61	228	COG1175	ABC-type sugar transport system, permease component	295
650066156	279	38.79	1	278	1	281	1.0e-55	210	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066157	459	20.13	4	457	2	433	7.0e-28	118	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066158	603	25.53	174	598	78	453	1.0e-39	158	COG2972	Sensor histidine kinase YesM	456
650066159	540	22.53	1	492	1	475	9.0e-34	138	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650066162	650	38.98	13	484	16	457	9.0e-105	374	COG4289	Uncharacterized protein	458
650066164	422	51	6	351	2	347	1.0e-121	430	COG1171	Threonine dehydratase	347
650066167	111	42.99	6	110	4	108	1.0e-17	81.4	COG1695	DNA-binding transcriptional regulator, PadR family	138
650066169	275	21.71	9	263	28	297	4.0e-10	59	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
650066170	258	46.97	1	258	7	267	2.0e-66	245	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
650066172	179	21.02	7	153	7	142	4.0e-05	41.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650066174	174	22.08	9	152	9	141	7.0e-05	40.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650066175	178	24	14	153	14	142	3.0e-05	41.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650066178	204	30.81	1	203	7	217	3.0e-29	121	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
650066179	329	40.55	5	328	2	322	4.0e-62	232	COG0306	Phosphate/sulfate permease	326
650066180	318	36.72	18	317	22	322	2.0e-63	236	COG0598	Mg2+ and Co2+ transporter CorA	322
650066183	96	70.21	1	94	1	94	1.0e-35	141	COG4496	Uncharacterized protein YerC	100
650066184	244	19.91	26	235	36	236	1.0e-11	63.5	COG2138	Sirohydrochlorin ferrochelatase	245
650066185	293	45.08	1	293	2	294	7.0e-76	277	COG1597	Diacylglycerol kinase family enzyme	301
650066186	502	43.25	30	495	1	432	0.0e+00	477	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
650066188	170	19.46	2	159	35	215	2.0e-03	35.7	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
650066194	223	47	4	216	1	214	8.0e-77	279	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
650066195	163	39.84	35	159	5	127	4.0e-21	94.2	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
650066196	244	29.66	5	240	1	212	6.0e-47	180	COG0602	Organic radical activating enzyme	212
650066201	234	18.64	27	193	59	226	1.0e-03	37.4	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
650066222	329	30.34	4	316	3	317	5.0e-66	244	COG0042	tRNA-dihydrouridine synthase	323
650066226	353	37.45	73	324	70	328	4.0e-47	182	COG3344	Retron-type reverse transcriptase	328
650066233	334	17.93	2	330	49	330	9.0e-26	111	COG0620	Methionine synthase II (cobalamin-independent)	330
650066237	234	46.46	4	223	1	226	4.0e-74	271	COG1136	ABC-type lipoprotein export system, ATPase component	226
650066238	775	18	1	384	6	406	8.0e-11	63	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
650066239	329	26.69	1	314	6	330	2.0e-43	169	COG0673	Predicted dehydrogenase	342
650066241	82	47.44	1	78	1	74	2.0e-08	50.8	COG4997	Predicted house-cleaning noncanonical NTP pyrophosphatase, all-alpha NTP-PPase (MazG) superfamily	95
650066251	316	20.49	59	298	53	284	2.0e-08	53.7	COG5006	Threonine/homoserine efflux transporter RhtA	292
650066252	450	30.91	18	447	5	434	2.0e-62	233	COG2233	Xanthine/uracil permease	451
650066253	454	26.63	71	451	56	407	5.0e-55	209	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
650066257	250	40.97	114	248	37	178	7.0e-28	117	COG2032	Cu/Zn superoxide dismutase	179
650066258	76	37.04	1	76	2	82	4.0e-15	72.7	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
650066259	113	42.34	6	112	1	110	1.0e-23	101	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
650066265	291	24.1	7	286	21	316	1.0e-16	80.4	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
650066266	506	38.52	16	498	28	509	9.0e-113	401	COG0513	Superfamily II DNA and RNA helicase	513
650066267	225	23.6	21	189	45	220	6.0e-08	51.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
650066268	215	20.99	28	199	30	210	5.0e-16	78	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650066272	201	51.69	105	193	2	89	7.0e-22	97.3	COG3860	Uncharacterized protein	89
650066277	228	32.11	1	217	1	218	4.0e-46	178	COG0819	Thiaminase	218
650066278	279	51.15	12	272	7	265	3.0e-69	255	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
650066280	211	45.28	1	209	1	207	1.0e-45	176	COG0352	Thiamine monophosphate synthase	211
650066281	390	25.88	1	383	1	396	6.0e-46	178	COG1301	Na+/H+-dicarboxylate symporter	415
650066284	398	23.08	1	91	2	92	1.0e-05	44.9	COG4842	Uncharacterized conserved protein YukE	97
650066289	630	24.44	309	572	16	271	3.0e-16	80.7	COG2339	Membrane proteinase PrsW, cleaves anti-sigma factor RsiW, M82 family	274
650066291	471	52.11	1	471	4	477	0.0e+00	550	COG0469	Pyruvate kinase	477
650066292	259	29.84	134	257	1	124	1.0e-18	87.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650066293	315	28.98	1	312	1	291	5.0e-49	188	COG1316	Anionic cell wall polymer biosynthesis enzyme,  LytR-Cps2A-Psr (LCP) family	307
650066294	347	35.21	10	347	5	333	7.0e-74	271	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650066295	442	28.03	4	441	3	433	2.0e-41	163	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066296	282	40.57	5	281	1	281	1.0e-56	213	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066297	294	36.95	3	294	2	294	2.0e-56	213	COG1175	ABC-type sugar transport system, permease component	295
650066300	233	27.35	1	220	6	222	9.0e-29	120	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650066302	248	35.9	3	111	1	117	2.0e-14	73.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
650066303	113	45.92	15	112	7	104	7.0e-28	115	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650066304	312	48.9	1	312	1	309	2.0e-85	309	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650066305	324	46.84	1	309	1	308	2.0e-88	319	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650066308	167	29.49	1	154	1	143	4.0e-11	61.1	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
650066309	309	25.41	1	180	30	193	1.0e-07	50.6	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
650066313	120	45.76	1	118	2	118	7.0e-31	125	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
650066316	450	27.79	8	446	13	447	1.0e-51	197	COG0534	Na+-driven multidrug efflux pump	455
650066317	873	27.45	4	871	2	892	2.0e-100	361	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
650066318	667	27.03	43	378	58	435	2.0e-45	177	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
650066320	497	50.5	1	494	3	501	0.0e+00	575	COG3845	ABC-type uncharacterized transport system, ATPase component	501
650066321	355	37.11	1	352	5	355	6.0e-62	231	COG4603	ABC-type uncharacterized transport system, permease component	356
650066322	224	41.83	11	209	46	253	2.0e-49	188	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
650066323	243	35.86	6	232	9	244	1.0e-44	173	COG2820	Uridine phosphorylase	248
650066324	156	19.74	6	147	5	156	5.0e-10	57.3	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650066326	172	23.17	1	163	4	167	9.0e-07	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650066327	318	20	3	248	2	259	1.0e-14	74.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650066329	155	31.06	5	153	19	178	2.0e-18	85.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650066333	625	46.42	3	624	6	618	0.0e+00	684	COG0326	Molecular chaperone, HSP90 family	623
650066335	383	25	12	373	18	388	4.0e-26	112	COG2814	Predicted arabinose efflux permease, MFS family	394
650066338	128	41.8	1	122	1	120	9.0e-28	115	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650066344	453	23.96	4	450	1	433	5.0e-38	152	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066345	321	43.43	23	317	1	290	8.0e-67	247	COG1175	ABC-type sugar transport system, permease component	295
650066346	274	37.91	2	274	5	281	4.0e-55	208	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066347	292	26.39	4	286	2	274	2.0e-28	119	COG1082	Sugar phosphate isomerase/epimerase	274
650066348	336	25.6	7	328	5	330	2.0e-27	116	COG0673	Predicted dehydrogenase	342
650066349	342	30.21	7	336	3	341	2.0e-55	210	COG0673	Predicted dehydrogenase	342
650066350	262	28.98	23	261	7	238	1.0e-40	160	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
650066351	387	36.31	26	384	25	380	1.0e-68	254	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
650066352	162	17.83	7	161	3	159	4.0e-05	41.1	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650066355	483	24.6	47	467	4	402	2.0e-43	170	COG2312	Erythromycin esterase homolog	405
650066356	65	56.92	1	65	2	65	2.0e-17	80.6	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
650066358	300	21.23	50	249	9	197	1.0e-04	41	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
650066359	143	35.51	4	140	1	133	4.0e-29	120	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
650066361	502	43.77	222	501	6	286	6.0e-66	245	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650066362	480	44.09	171	474	2	314	1.0e-81	297	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650066363	580	54.96	1	538	2	538	0.0e+00	705	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
650066364	211	23	1	204	2	206	3.0e-15	75.3	COG2755	Lysophospholipase L1 or related esterase	216
650066365	373	27.18	50	331	29	309	2.0e-26	113	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650066366	331	38.22	19	330	7	311	7.0e-48	184	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650066369	332	27.22	1	321	2	333	2.0e-46	179	COG0673	Predicted dehydrogenase	342
650066370	358	26.67	6	330	13	330	3.0e-49	189	COG3239	Fatty acid desaturase	343
650066371	377	23.32	1	365	4	364	3.0e-46	179	COG4585	Signal transduction histidine kinase	365
650066372	200	39.9	2	198	1	208	4.0e-48	184	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650066375	162	47.8	4	162	3	160	4.0e-39	153	COG0490	K+/H+ antiporter YhaU, regulatory subunit KhtT	162
650066376	249	32.14	1	244	1	249	4.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650066378	394	17.66	9	356	12	349	3.0e-08	53.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
650066379	230	41.85	6	230	3	226	2.0e-61	229	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650066382	748	17.88	407	707	32	339	9.0e-04	39.4	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
650066387	484	21.41	55	482	33	461	5.0e-24	106	COG0471	Di- and tricarboxylate transporter	461
650066390	769	31.97	648	769	2	123	2.0e-19	91.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650066391	306	47.87	2	306	7	309	3.0e-95	341	COG4209	ABC-type polysaccharide transport system, permease component	309
650066392	286	30.14	10	285	8	281	2.0e-45	176	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066393	516	22.34	3	374	2	349	3.0e-20	93.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066394	119	35.34	1	114	3	103	6.0e-17	79.6	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
650066396	180	35.06	5	178	8	181	7.0e-30	123	COG2059	Chromate transport protein ChrA	195
650066397	189	36.93	2	177	9	184	6.0e-33	133	COG2059	Chromate transport protein ChrA	195
650066398	160	32.89	14	160	6	154	7.0e-28	116	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650066399	365	26.5	54	356	38	350	4.0e-35	142	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
650066401	108	25	12	104	1	100	6.0e-11	59.2	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
650066402	332	28.07	6	331	1	339	5.0e-49	188	COG0673	Predicted dehydrogenase	342
650066404	1191	29.88	472	874	30	415	3.0e-75	277	COG1649	Uncharacterized lipoprotein YddW, UPF0748 family	418
650066405	212	22	1	198	14	213	3.0e-20	91.9	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
650066406	556	20.77	1	539	1	489	5.0e-48	185	COG3428	Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain	494
650066407	160	32.92	4	159	2	160	2.0e-25	108	COG3402	Uncharacterized membrane protein YdbS, contains bPH2 (bacterial pleckstrin homology) domain	161
650066408	261	31.2	1	234	5	233	4.0e-42	165	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650066410	169	29.03	14	167	6	154	2.0e-16	78.5	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
650066414	758	46.45	6	643	3	645	0.0e+00	651	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
650066416	296	47.62	3	296	16	309	1.0e-93	336	COG4209	ABC-type polysaccharide transport system, permease component	309
650066417	293	31.54	1	292	1	281	2.0e-45	176	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066418	539	19.8	3	394	1	349	3.0e-18	87	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066420	1274	34.94	308	823	20	517	5.0e-88	320	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
650066422	327	22.14	23	162	1	140	4.0e-04	39.4	COG2510	Uncharacterized membrane protein	140
650066423	180	26.23	2	179	1	179	4.0e-13	67.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650066425	320	47.25	13	320	1	309	2.0e-86	312	COG4209	ABC-type polysaccharide transport system, permease component	309
650066426	290	28.81	1	289	1	281	1.0e-42	166	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066428	266	26.29	29	257	30	244	1.0e-19	90.8	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
650066429	224	28.23	1	208	7	214	2.0e-31	129	COG1802	DNA-binding transcriptional regulator, GntR family	230
650066430	693	56.43	17	693	11	682	0.0e+00	929	COG3661	Alpha-glucuronidase	684
650066431	257	42.91	1	253	18	270	1.0e-67	249	COG4326	Sporulation-control protein spo0M	270
650066432	532	46.14	84	522	3	432	2.0e-130	460	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
650066433	515	29.11	1	231	1	222	1.0e-22	101	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650066442	573	17.26	1	571	4	590	2.0e-15	78.1	COG5293	Uncharacterized protein YydD, contains DUF2326 domain	591
650066447	950	34.33	106	419	13	347	2.0e-21	98.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
650066449	306	26.29	47	296	32	225	1.0e-18	87.7	COG3910	Predicted ATPase	233
650066451	191	41.76	5	94	4	93	1.0e-13	69.9	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
650066452	235	17.16	33	201	41	204	1.0e-04	40	COG4912	3-methyladenine DNA glycosylase AlkD	222
650066454	287	31.09	1	233	1	227	4.0e-39	155	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
650066455	125	29.03	1	123	1	124	1.0e-15	75.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
650066460	570	22.25	23	356	23	371	9.0e-32	132	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
650066465	160	26.06	11	132	7	148	7.0e-10	57	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
650066466	334	23.1	8	323	8	324	2.0e-32	133	COG4927	Predicted choloylglycine hydrolase	336
650066469	577	38.22	3	571	2	567	7.0e-123	434	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650066470	619	42.86	40	613	3	564	0.0e+00	499	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650066472	258	21.67	3	258	8	268	6.0e-19	88	COG4587	ABC-type uncharacterized transport system, permease component	268
650066473	266	25.09	4	266	2	260	7.0e-28	117	COG3694	ABC-type uncharacterized transport system, permease component	260
650066474	330	44.55	1	330	3	321	9.0e-87	313	COG4586	ABC-type uncharacterized transport system, ATPase component	325
650066477	278	44.44	1	277	2	268	5.0e-71	261	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
650066478	410	48.19	1	409	3	414	2.0e-121	429	COG2195	Di- or tripeptidase	414
650066479	336	43.9	3	242	9	252	4.0e-58	218	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
650066480	206	46.63	1	206	3	209	2.0e-53	201	COG0352	Thiamine monophosphate synthase	211
650066481	66	33.33	1	66	3	68	5.0e-08	49.4	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
650066482	260	56.98	1	258	2	259	7.0e-96	343	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
650066483	375	31.95	1	371	3	382	5.0e-47	182	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650066484	299	35	169	287	3	122	7.0e-24	104	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650066485	432	41.72	3	431	5	439	0.0e+00	482	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
650066488	435	26.84	104	435	2	334	4.0e-34	139	COG0642	Signal transduction histidine kinase	336
650066489	336	37.42	6	329	3	314	6.0e-68	251	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650066490	278	33.1	1	278	11	288	2.0e-46	179	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650066491	304	42.47	1	288	28	312	2.0e-84	305	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650066495	221	34.11	2	214	1	211	3.0e-38	152	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650066496	665	36.22	295	664	31	408	2.0e-52	200	COG0840	Methyl-accepting chemotaxis protein	408
650066497	292	32.43	175	285	16	126	8.0e-21	94.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650066498	499	35.24	1	443	2	442	1.0e-116	413	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
650066499	372	67.12	1	370	1	370	0.0e+00	523	COG0686	Alanine dehydrogenase	371
650066500	230	39.17	1	226	3	242	4.0e-58	217	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
650066501	186	39.44	1	180	1	179	5.0e-42	164	COG4474	Uncharacterized SPBc2 prophage-derived protein YoqJ	180
650066504	178	31.29	17	176	17	179	2.0e-26	112	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650066506	171	25.83	4	154	2	151	2.0e-19	89.2	COG3663	G:T/U-mismatch repair DNA glycosylase	169
650066507	284	43.31	1	281	3	270	7.0e-83	300	COG2107	Predicted periplasmic solute-binding protein	272
650066508	238	22.41	40	213	34	206	5.0e-14	71.6	COG0775	Nucleoside phosphorylase	234
650066509	199	22.68	1	192	3	195	1.0e-10	59.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650066511	335	29.43	40	335	31	318	8.0e-43	167	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650066512	644	28.29	127	628	13	452	1.0e-59	224	COG2972	Sensor histidine kinase YesM	456
650066514	361	44.03	10	361	3	341	3.0e-108	385	COG4213	ABC-type xylose transport system, periplasmic component	341
650066515	510	48.32	1	505	4	498	0.0e+00	616	COG1129	ABC-type sugar transport system, ATPase component	500
650066517	292	25.76	1	288	1	293	3.0e-38	152	COG1131	ABC-type multidrug transport system, ATPase component	293
650066518	128	32.74	8	120	8	119	5.0e-20	90.3	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
650066521	289	39.64	9	288	1	279	2.0e-56	212	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
650066522	320	33.65	1	311	5	309	5.0e-57	215	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
650066523	426	23.86	1	426	1	433	6.0e-38	152	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066524	309	39.87	10	307	1	295	2.0e-57	216	COG1175	ABC-type sugar transport system, permease component	295
650066525	277	44.64	1	277	3	281	2.0e-59	222	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066526	225	51.85	6	221	16	229	2.0e-62	232	COG3010	Putative N-acetylmannosamine-6-phosphate epimerase	229
650066528	357	53.28	1	351	35	384	0.0e+00	475	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
650066529	307	27.72	5	302	4	306	7.0e-22	98.1	COG0679	Predicted permease	311
650066530	239	38.89	1	226	2	232	3.0e-45	175	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
650066532	239	50	71	225	1	156	1.0e-46	179	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
650066537	485	34.36	3	479	9	527	2.0e-103	370	COG0659	Sulfate permease or related transporter, MFS superfamily	554
650066538	635	24.33	310	635	1	336	1.0e-35	144	COG0642	Signal transduction histidine kinase	336
650066539	621	23.56	300	619	1	330	5.0e-34	139	COG0642	Signal transduction histidine kinase	336
650066545	480	44.61	7	474	7	478	6.0e-122	431	COG3263	NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains	574
650066546	157	42.31	1	156	1	156	3.0e-39	154	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
650066548	165	59.06	4	152	1	149	9.0e-56	209	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
650066549	224	28.64	1	220	18	212	1.0e-41	163	COG0602	Organic radical activating enzyme	212
650066550	206	41.67	35	127	5	99	1.0e-18	86.5	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
650066551	225	46.76	3	213	1	213	4.0e-76	277	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
650066560	593	31.94	26	326	42	326	1.0e-26	114	COG3344	Retron-type reverse transcriptase	328
650066564	381	25.94	4	381	1	377	3.0e-34	139	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650066568	253	29.55	5	239	5	248	1.0e-32	133	COG1216	Glycosyltransferase, GT2 family	305
650066569	243	50	1	235	1	232	3.0e-71	261	COG1209	dTDP-glucose pyrophosphorylase	286
650066575	365	27.74	87	361	77	361	2.0e-29	123	COG4641	Spore maturation protein CgeB	373
650066576	374	27.99	103	372	77	359	7.0e-30	125	COG4641	Spore maturation protein CgeB	373
650066577	466	19.53	6	384	1	370	5.0e-18	86.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650066578	364	33.97	1	357	4	369	2.0e-80	293	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
650066580	319	27.62	10	311	2	309	9.0e-29	120	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650066582	395	43.86	14	395	7	379	6.0e-108	384	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
650066583	242	38.71	1	241	1	236	9.0e-58	216	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
650066584	291	34.97	1	286	2	281	3.0e-59	222	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
650066589	439	23.82	4	437	3	428	2.0e-35	144	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066590	293	35.86	1	288	2	291	2.0e-55	209	COG1175	ABC-type sugar transport system, permease component	295
650066591	294	42.6	20	293	5	281	2.0e-56	213	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066594	83	41.79	10	76	3	69	2.0e-11	60.6	COG1918	Fe2+ transport system protein FeoA	75
650066595	101	41.24	6	101	4	100	2.0e-09	54	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650066596	576	42.56	1	567	1	498	0.0e+00	531	COG0442	Prolyl-tRNA synthetase	500
650066597	297	33.21	20	296	2	281	3.0e-49	188	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066598	294	38.1	1	293	2	293	5.0e-57	214	COG1175	ABC-type sugar transport system, permease component	295
650066604	465	30.49	100	463	112	453	6.0e-52	198	COG2972	Sensor histidine kinase YesM	456
650066607	299	23.58	4	247	33	246	8.0e-15	74.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650066609	393	56.91	1	360	1	361	0.0e+00	497	COG0448	ADP-glucose pyrophosphorylase	393
650066610	367	34.16	1	354	3	363	7.0e-85	307	COG0448	ADP-glucose pyrophosphorylase	393
650066613	187	33.75	16	167	1	160	2.0e-37	149	COG1267	Phosphatidylglycerophosphatase A	160
650066614	352	26.04	65	348	10	246	9.0e-21	94.6	COG5401	Spore germination protein GerM	250
650066615	252	55.88	1	237	8	230	3.0e-74	271	COG0689	Ribonuclease PH	230
650066616	210	49.01	8	209	3	193	7.0e-58	217	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
650066617	614	37.04	1	573	1	516	6.0e-120	425	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
650066626	254	26.98	6	184	3	185	6.0e-15	75	COG4106	Trans-aconitate methyltransferase	257
650066627	142	50	1	142	1	140	2.0e-25	108	COG2510	Uncharacterized membrane protein	140
650066628	155	23.97	1	131	12	156	1.0e-06	45.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650066631	442	47.52	1	442	1	439	1.0e-96	347	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
650066632	196	73.06	1	193	1	193	5.0e-83	300	COG0740	ATP-dependent protease ClpP, protease subunit	200
650066633	421	71.08	14	419	1	408	0.0e+00	683	COG1219	ATP-dependent protease Clp, ATPase subunit	408
650066634	369	59.5	4	360	3	360	0.0e+00	497	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
650066635	588	24.82	7	492	19	562	1.0e-86	314	COG1067	Predicted ATP-dependent protease	647
650066636	778	63.54	10	774	9	776	0.0e+00	1131	COG0466	ATP-dependent Lon protease, bacterial type	782
650066637	214	49.49	1	196	2	199	4.0e-65	240	COG0218	GTP-binding protein EngB required for normal cell division	200
650066639	132	40.65	5	127	13	135	7.0e-36	142	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
650066640	468	46.68	1	422	1	414	1.0e-126	446	COG0373	Glutamyl-tRNA reductase	414
650066641	264	18.81	49	263	38	253	3.0e-07	49.4	COG4137	ABC-type uncharacterized transport system, permease component	265
650066642	218	36.32	5	205	2	201	1.0e-41	162	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
650066643	318	54.86	1	317	1	306	6.0e-110	390	COG0181	Porphobilinogen deaminase	307
650066644	518	52.23	1	247	2	244	1.0e-85	310	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
650066645	333	62.28	1	332	3	329	0.0e+00	525	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
650066646	431	65.72	11	431	7	429	0.0e+00	640	COG0001	Glutamate-1-semialdehyde aminotransferase	432
650066647	300	41.35	60	287	55	289	2.0e-54	206	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
650066649	889	56.63	12	889	1	877	0.0e+00	1252	COG0525	Valyl-tRNA synthetase	877
650066650	467	38.96	23	459	2	423	9.0e-106	377	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
650066651	458	49.67	1	452	4	455	0.0e+00	508	COG0773	UDP-N-acetylmuramate-alanine ligase	459
650066654	203	50	6	201	2	193	6.0e-56	210	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
650066655	229	53.12	6	229	1	224	3.0e-72	264	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
650066656	291	30.47	10	288	6	272	9.0e-47	180	COG1792	Cell shape-determining protein MreC	284
650066657	174	26.25	9	167	10	167	5.0e-09	54	COG2891	Cell shape-determining protein MreD	167
650066658	220	27.98	8	205	1	218	2.0e-26	113	COG0850	Septum formation inhibitor MinC	219
650066659	264	59.78	1	262	1	271	4.0e-107	380	COG2894	Septum formation inhibitor-activating ATPase MinD	272
650066661	287	23.32	13	193	30	215	2.0e-07	50.4	COG1994	Zn-dependent protease (includes SpoIVFB)	230
650066662	396	42.17	2	395	16	408	4.0e-95	341	COG1530	Ribonuclease G or E	487
650066663	103	60.19	1	103	1	103	9.0e-32	128	COG0261	Ribosomal protein L21	103
650066664	110	40.74	1	107	1	106	1.0e-19	88.4	COG2868	Uncharacterized conserved protein YsxB, DUF464 family	109
650066665	103	71.43	9	92	1	84	2.0e-33	133	COG0211	Ribosomal protein L27	87
650066668	436	51.76	1	369	2	369	0.0e+00	500	COG0536	GTPase involved in cell partioning and DNA repair	369
650066669	443	25.64	4	346	12	344	5.0e-41	162	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
650066677	428	46.85	1	324	1	333	5.0e-102	364	COG0460	Homoserine dehydrogenase	333
650066678	357	49.85	1	332	49	385	8.0e-103	367	COG0498	Threonine synthase	411
650066679	323	41.41	7	302	4	294	3.0e-78	285	COG0083	Homoserine kinase	299
650066680	295	39.86	1	285	2	275	7.0e-69	254	COG0077	Prephenate dehydratase	279
650066681	294	40.35	3	284	1	280	1.0e-68	253	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
650066690	167	49.01	4	154	1	150	3.0e-52	197	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
650066691	178	38.64	2	175	29	200	8.0e-42	163	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
650066692	335	71.08	2	333	1	332	0.0e+00	548	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
650066694	343	63.4	1	343	1	343	0.0e+00	525	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
650066695	379	62.43	10	371	2	363	0.0e+00	568	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
650066696	116	48.19	27	109	4	86	5.0e-23	99.5	COG1862	Preprotein translocase subunit YajC	97
650066698	265	35.09	1	265	1	224	1.0e-48	186	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
650066699	534	22.87	1	513	3	477	3.0e-19	90.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
650066701	416	35.01	15	404	90	505	9.0e-80	291	COG0342	Preprotein translocase subunit SecD	506
650066702	305	40.86	4	300	8	305	2.0e-67	249	COG0341	Preprotein translocase subunit SecF	305
650066703	321	29.9	1	307	3	298	2.0e-36	146	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
650066705	171	51.45	1	171	6	178	1.0e-42	166	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
650066706	432	40.05	7	415	9	439	2.0e-80	293	COG2233	Xanthine/uracil permease	451
650066707	725	52.49	1	723	7	701	0.0e+00	924	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
650066708	147	66.9	1	145	1	145	2.0e-61	228	COG1490	D-Tyr-tRNAtyr deacylase	145
650066710	168	47.51	1	168	2	182	6.0e-33	133	COG0693	Putative intracellular protease/amidase	188
650066712	591	63.42	2	586	1	585	0.0e+00	931	COG0173	Aspartyl-tRNA synthetase	585
650066713	251	49.6	1	246	9	258	5.0e-88	317	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
650066715	435	49.41	17	434	14	430	0.0e+00	485	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
650066717	742	30.5	2	742	4	699	0.0e+00	476	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
650066718	167	31.85	9	153	11	167	6.0e-18	83.9	COG0602	Organic radical activating enzyme	212
650066719	139	39.04	1	139	1	146	2.0e-34	138	COG1959	DNA-binding transcriptional regulator, IscR family	150
650066722	381	51.84	4	381	3	380	0.0e+00	484	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
650066723	173	27.39	2	157	3	151	1.0e-17	83.1	COG3881	Uncharacterized protein YrrD, contains PRC-barrel domain	176
650066725	355	34.59	8	349	1	344	1.0e-40	160	COG0628	Predicted PurR-regulated permease PerM	355
650066726	875	55.73	1	873	6	877	0.0e+00	1163	COG0013	Alanyl-tRNA synthetase	879
650066727	86	59.3	1	86	1	85	6.0e-27	112	COG4472	Uncharacterized protein, UPF0297 family	88
650066728	137	52.9	1	137	1	138	1.0e-40	158	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
650066729	100	36.46	8	97	9	104	5.0e-04	36.1	COG3906	Uncharacterized protein YrzB, UPF0473 family	105
650066731	347	37.75	1	343	9	338	2.0e-79	289	COG1559	Cell division protein YceG, involved in septum cleavage	342
650066732	310	35.6	4	310	6	307	1.0e-61	230	COG0826	Collagenase-like protease, PrtC family	347
650066733	448	42.97	13	394	1	347	4.0e-97	348	COG0826	Collagenase-like protease, PrtC family	347
650066734	765	22.94	363	750	37	407	3.0e-35	144	COG0840	Methyl-accepting chemotaxis protein	408
650066735	598	28.81	2	582	10	584	2.0e-74	273	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
650066736	389	26.39	15	354	16	346	2.0e-26	113	COG0628	Predicted PurR-regulated permease PerM	355
650066737	461	33.02	31	239	58	266	2.0e-31	130	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650066738	557	59.72	1	557	11	572	0.0e+00	782	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650066741	255	26.25	14	251	5	213	5.0e-24	104	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
650066742	250	40.41	6	244	1	241	2.0e-65	242	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
650066743	341	41.67	13	332	1	312	2.0e-80	292	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650066744	289	36.72	158	285	1	127	4.0e-22	98.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650066745	386	48.83	1	382	3	383	2.0e-117	415	COG0153	Galactokinase	390
650066746	329	55.62	1	326	1	329	0.0e+00	512	COG1087	UDP-glucose 4-epimerase	329
650066747	510	54.37	2	504	10	501	0.0e+00	629	COG4468	Galactose-1-phosphate uridylyltransferase	503
650066748	387	50.13	1	387	1	384	0.0e+00	529	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
650066750	511	36.19	1	475	8	528	7.0e-65	241	COG2268	Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain	548
650066752	693	39.13	1	422	1	393	9.0e-81	295	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
650066753	91	40.23	2	88	3	88	6.0e-18	82.2	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
650066754	573	60.53	4	566	3	567	0.0e+00	810	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
650066755	791	30.38	23	678	65	691	2.0e-116	413	COG1523	Pullulanase/glycogen debranching enzyme	697
650066756	208	39.13	8	96	3	93	2.0e-16	79.1	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
650066757	293	33.33	52	285	26	271	4.0e-33	135	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650066758	250	39.92	4	247	1	250	2.0e-47	182	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650066759	249	41.2	1	247	1	248	2.0e-52	199	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650066760	277	58.27	1	277	1	278	1.0e-113	403	COG3717	5-keto 4-deoxyuronate isomerase	278
650066761	299	42.91	49	288	7	250	7.0e-53	200	COG0584	Glycerophosphoryl diester phosphodiesterase	257
650066762	419	39.13	40	399	1	366	3.0e-72	265	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650066763	301	39.2	1	299	3	296	6.0e-53	201	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650066764	279	54.84	24	271	2	249	8.0e-92	330	COG4674	ABC-type uncharacterized transport system, ATPase component	249
650066765	231	45.53	1	231	3	237	4.0e-75	274	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650066766	495	65.05	1	495	2	496	0.0e+00	741	COG2160	L-arabinose isomerase	497
650066767	401	32.44	36	362	4	331	1.0e-55	210	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650066768	229	39.74	1	229	4	219	1.0e-61	229	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650066769	556	39.96	3	553	2	541	0.0e+00	572	COG1069	Ribulose kinase	544
650066771	331	34.34	27	320	68	337	8.0e-57	214	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
650066773	305	42.76	2	302	5	308	7.0e-93	333	COG4189	Predicted transcriptional regulator	308
650066774	499	54.2	1	499	2	501	0.0e+00	689	COG3534	Alpha-L-arabinofuranosidase	501
650066775	442	23.23	1	442	1	431	1.0e-36	148	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066776	297	35.14	3	296	2	293	5.0e-48	185	COG1175	ABC-type sugar transport system, permease component	295
650066777	277	37.77	2	276	5	281	5.0e-50	191	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066779	289	29.04	25	288	16	276	1.0e-20	94.1	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
650066780	414	30.73	1	379	4	381	7.0e-36	144	COG0475	Kef-type K+ transport system, membrane component KefB	397
650066781	163	49.69	1	163	1	162	8.0e-42	163	COG0490	K+/H+ antiporter YhaU, regulatory subunit KhtT	162
650066787	612	30.2	201	604	87	454	1.0e-44	175	COG2972	Sensor histidine kinase YesM	456
650066791	283	49.82	1	283	27	309	5.0e-90	324	COG4209	ABC-type polysaccharide transport system, permease component	309
650066792	305	29.41	22	304	6	281	7.0e-45	174	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066793	512	22.84	71	415	46	393	5.0e-19	89.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066794	1551	19.25	521	908	50	383	4.0e-12	68.5	COG1649	Uncharacterized lipoprotein YddW, UPF0748 family	418
650066798	233	27.83	28	233	17	222	7.0e-29	120	COG2091	Phosphopantetheinyl transferase	223
650066801	509	21.34	1	415	1	391	2.0e-24	107	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066802	512	20.73	2	380	1	349	8.0e-24	105	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650066803	319	53.57	12	319	2	309	5.0e-107	381	COG4209	ABC-type polysaccharide transport system, permease component	309
650066804	292	30.03	5	291	3	281	5.0e-48	184	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650066805	475	28.63	7	471	23	547	4.0e-61	229	COG3507	Beta-xylosidase	549
650066807	105	36.36	5	98	21	119	4.0e-11	59.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
650066809	353	22.18	74	316	8	224	2.0e-11	63.9	COG0412	Dienelactone hydrolase	236
650066810	233	36.25	28	231	3	247	1.0e-37	150	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
650066811	477	21.7	37	476	2	413	9.0e-36	145	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
650066812	340	36.39	3	333	106	441	7.0e-47	181	COG2610	H+/gluconate symporter or related permease	442
650066814	297	47.9	1	285	1	286	7.0e-81	294	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650066815	207	37.21	1	204	9	223	1.0e-31	129	COG1802	DNA-binding transcriptional regulator, GntR family	230
650066819	267	40.07	2	264	55	318	1.0e-58	220	COG3458	Cephalosporin-C deacetylase or related acetyl esterase	321
650066820	123	18.42	3	114	4	117	8.0e-03	32.6	COG5609	Uncharacterized protein YbcI	124
650066821	259	48.63	2	256	1	248	2.0e-85	309	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650066822	293	30.47	38	293	2	257	2.0e-43	169	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650066823	335	25.47	21	335	20	330	1.0e-23	103	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650066824	220	33.66	11	200	4	202	4.0e-31	128	COG1335	Nicotinamidase-related amidase	205
650066825	479	22.83	23	364	16	383	2.0e-18	87.2	COG2814	Predicted arabinose efflux permease, MFS family	394
650066826	357	46.76	3	354	2	355	2.0e-112	399	COG1363	Putative aminopeptidase FrvX	355
650066831	318	44	1	314	5	329	4.0e-72	265	COG0714	MoxR-like ATPase	329
650066832	415	21.77	16	411	7	408	3.0e-28	119	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
650066833	176	45.78	1	166	2	165	7.0e-44	170	COG2179	Predicted phosphohydrolase YqeG, HAD superfamily	175
650066834	374	29.71	41	374	1	322	5.0e-47	181	COG1161	Ribosome biogenesis GTPase A	322
650066835	286	45.39	7	286	2	283	4.0e-83	301	COG0169	Shikimate 5-dehydrogenase	283
650066836	96	62.5	1	96	1	96	9.0e-28	114	COG1534	RNA-binding protein YhbY	97
650066837	196	41.75	1	192	3	195	2.0e-51	195	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
650066838	192	43.85	3	189	1	187	7.0e-49	186	COG1713	HD superfamily phosphohydrolase YqeK (fused to NMNAT in mycoplasms)	187
650066839	115	50	6	113	4	111	4.0e-33	133	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
650066840	291	42.18	1	272	1	268	1.0e-62	233	COG2996	Predicted RNA-binding protein, contains S1 domains,  virulence factor B family	287
650066842	288	20.96	1	262	3	253	5.0e-20	91.8	COG1082	Sugar phosphate isomerase/epimerase	274
650066843	389	28.93	1	352	1	342	3.0e-50	192	COG0673	Predicted dehydrogenase	342
650066844	361	26.09	44	361	26	340	8.0e-25	108	COG0673	Predicted dehydrogenase	342
650066845	294	35.9	171	287	6	121	1.0e-19	90.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650066847	280	34.09	1	262	2	262	2.0e-53	202	COG0345	Pyrroline-5-carboxylate reductase	266
650066849	172	37.82	7	158	6	152	7.0e-34	136	COG2131	Deoxycytidylate deaminase	164
650066850	884	33.45	595	881	46	285	9.0e-48	185	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
650066851	181	32.2	1	173	1	177	2.0e-32	132	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650066853	90	60.23	1	88	1	88	8.0e-10	55.3	COG0268	Ribosomal protein S20	88
650066856	604	71.5	5	604	3	602	0.0e+00	1093	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
650066857	388	43.27	10	385	36	413	8.0e-110	390	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
650066858	153	35.57	6	152	4	152	3.0e-29	121	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
650066859	344	40.41	1	344	3	345	1.0e-92	333	COG1420	Transcriptional regulator of heat shock response	346
650066860	511	28.96	17	505	12	512	3.0e-62	233	COG0459	Chaperonin GroEL (HSP60 family)	524
650066861	198	42.33	10	197	5	190	1.0e-37	149	COG0576	Molecular chaperone GrpE (heat shock protein)	193
650066862	612	64.09	1	576	4	579	0.0e+00	680	COG0443	Molecular chaperone DnaK (HSP70)	579
650066863	372	59.68	4	371	3	371	0.0e+00	485	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
650066866	325	40.62	1	325	2	300	5.0e-78	284	COG2264	Ribosomal protein L11 methylase PrmA	300
650066867	230	32.18	20	209	21	210	1.0e-14	73.5	COG1994	Zn-dependent protease (includes SpoIVFB)	230
650066868	256	41.27	1	252	3	246	3.0e-58	219	COG1385	16S rRNA U1498 N3-methylase RsmE	246
650066869	447	39.41	1	435	2	436	0.0e+00	478	COG0621	tRNA A37 methylthiotransferase MiaB	437
650066872	457	39.43	4	452	1	393	4.0e-98	351	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
650066874	1176	36.09	1	1174	1	1108	0.0e+00	850	COG3857	ATP-dependent helicase/DNAse subunit B	1108
650066875	392	27.79	1	387	1	390	2.0e-43	170	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
650066876	1151	22.63	1	813	1	779	2.0e-28	121	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
650066877	119	38.39	1	110	1	109	4.0e-26	109	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
650066879	146	53.06	1	146	1	147	1.0e-37	148	COG1610	Uncharacterized conserved protein YqeY	148
650066880	453	31.03	33	451	19	431	4.0e-68	252	COG1030	Membrane-bound serine protease (ClpP class)	436
650066881	335	74.54	6	331	2	327	2.0e-130	459	COG4864	Uncharacterized protein YqfA, UPF0365 family	328
650066885	323	51.83	1	323	9	336	2.0e-103	369	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
650066886	760	38.4	10	738	1	697	0.0e+00	544	COG1480	Membrane-associated HD superfamily phosphohydrolase	700
650066887	165	39.24	8	165	6	148	3.0e-32	131	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
650066888	127	47.32	8	119	11	122	8.0e-24	102	COG0818	Diacylglycerol kinase	123
650066889	137	50.75	1	134	3	134	6.0e-41	159	COG0295	Cytidine deaminase	134
650066891	262	34.14	11	257	3	243	1.0e-46	180	COG1381	Recombinational DNA repair protein (RecF pathway)	251
650066892	295	71.67	1	289	5	297	0.0e+00	547	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
650066893	157	37.41	7	153	2	148	4.0e-38	150	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
650066894	605	33.62	8	584	2	555	3.0e-108	386	COG0358	DNA primase (bacterial type)	568
650066895	376	54.81	41	376	1	342	1.0e-95	343	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
650066896	242	41.88	2	234	12	225	5.0e-53	200	COG2384	tRNA A22 N-methylase	226
650066905	386	49.21	1	378	2	381	8.0e-129	453	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
650066906	412	45.93	3	381	2	379	6.0e-116	411	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
650066909	220	25.75	2	213	15	246	3.0e-24	105	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
650066911	613	67.22	4	604	2	601	0.0e+00	1012	COG1217	Predicted membrane GTPase involved in stress response	603
650066913	365	25.69	27	348	1	291	8.0e-36	144	COG1316	Anionic cell wall polymer biosynthesis enzyme,  LytR-Cps2A-Psr (LCP) family	307
650066916	443	55.38	1	443	1	436	0.0e+00	527	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
650066917	420	20.58	66	352	52	349	4.0e-12	66.1	COG2182	Maltose-binding periplasmic protein MalE	420
650066920	321	33.96	3	319	1	299	4.0e-54	205	COG1893	Ketopantoate reductase	307
650066922	552	33.04	1	546	3	553	5.0e-112	398	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
650066923	310	40.25	1	306	1	317	2.0e-75	276	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650066924	316	48.94	37	316	7	288	5.0e-80	291	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650066925	300	60.81	4	298	1	292	3.0e-126	444	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650066927	543	32.58	12	541	12	535	6.0e-92	331	COG4365	Uncharacterized protein YllA, UPF0747 family	537
650066928	422	55.34	11	421	7	418	0.0e+00	582	COG0499	S-adenosylhomocysteine hydrolase	420
650066929	145	47.95	1	143	1	146	3.0e-52	197	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
650066930	317	53.31	1	317	4	312	6.0e-124	437	COG0275	16S rRNA C1402 N4-methylase RsmH	314
650066931	138	29.2	7	116	3	114	3.0e-05	41.1	COG4839	Cell division protein FtsL	120
650066932	647	40	1	569	6	599	0.0e+00	465	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
650066933	495	47.08	22	493	9	475	0.0e+00	475	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
650066934	472	46.3	5	462	4	450	2.0e-128	452	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
650066935	321	41.36	5	321	4	316	1.0e-53	203	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
650066936	479	43.63	3	479	1	446	4.0e-129	455	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
650066937	365	47.92	9	365	15	373	8.0e-83	300	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
650066940	301	45.94	19	300	6	288	4.0e-87	314	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
650066941	427	55.5	1	415	1	417	0.0e+00	537	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
650066942	256	19.77	1	254	13	265	5.0e-19	88.2	COG1589	Cell division septal protein FtsQ	269
650066943	427	43.09	1	427	2	418	2.0e-107	382	COG0849	Cell division ATPase FtsA	418
650066944	375	59.29	1	338	1	338	8.0e-106	377	COG0206	Cell division GTPase FtsZ	338
650066946	240	37.85	35	238	1	246	2.0e-39	156	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
650066947	260	38.96	14	259	1	245	2.0e-57	216	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
650066948	113	31.76	7	91	1	84	4.0e-12	63.3	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
650066949	285	42.97	29	284	14	249	1.0e-60	226	COG1496	Copper oxidase (laccase) domain	249
650066950	229	45.65	1	228	1	227	7.0e-72	263	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
650066953	89	37.21	4	89	10	94	2.0e-05	40.9	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
650066954	260	40.23	4	259	3	256	2.0e-66	245	COG2302	RNA-binding protein YlmH, contains S4-like domain	257
650066956	246	33.91	4	118	1	106	4.0e-15	75.1	COG1734	RNA polymerase-binding transcription factor DksA	120
650066958	166	45.45	1	152	11	163	2.0e-34	138	COG0597	Lipoprotein signal peptidase	167
650066959	323	51.7	24	311	3	289	2.0e-88	319	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
650066961	527	39.55	1	525	1	512	0.0e+00	470	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650066963	415	31.3	29	409	10	393	2.0e-81	296	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650066964	186	58.79	3	184	1	179	4.0e-60	224	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
650066965	303	46.79	6	303	4	313	5.0e-97	347	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
650066966	1068	68.19	13	405	1	392	0.0e+00	581	COG0458	Carbamoylphosphate synthase large subunit	400
650066967	247	44.26	1	244	1	234	2.0e-55	209	COG0284	Orotidine-5'-phosphate decarboxylase	240
650066968	213	37.62	9	208	4	200	3.0e-46	178	COG0461	Orotate phosphoribosyltransferase	201
650066969	305	33.67	1	292	2	288	3.0e-62	232	COG1131	ABC-type multidrug transport system, ATPase component	293
650066971	194	23.03	2	165	11	175	6.0e-11	60.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650066977	90	26.67	1	90	1	90	2.0e-05	40.3	COG4842	Uncharacterized conserved protein YukE	97
650066989	401	23.41	6	396	10	394	2.0e-25	110	COG2814	Predicted arabinose efflux permease, MFS family	394
650066990	205	22.11	1	196	3	201	5.0e-13	67.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650066991	257	41.26	51	251	61	265	3.0e-41	162	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650066994	230	58.11	3	222	2	223	2.0e-92	331	COG0692	Uracil DNA glycosylase	223
650066996	358	30.92	13	357	9	351	6.0e-38	151	COG0628	Predicted PurR-regulated permease PerM	355
650066999	492	22.88	5	351	1	337	2.0e-20	93.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067000	305	33.22	18	304	10	281	7.0e-48	184	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650067001	1040	34.63	234	1036	201	942	0.0e+00	523	COG0383	Alpha-mannosidase	943
650067002	439	54.35	17	430	7	419	0.0e+00	567	COG3538	Meiotically up-regulated gene 157 (Mug157) protein (function unknown)	434
650067004	911	32.49	6	908	5	943	0.0e+00	617	COG0383	Alpha-mannosidase	943
650067007	127	22.06	6	121	2	136	4.0e-07	47.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650067009	261	38.46	5	236	3	236	2.0e-61	229	COG1131	ABC-type multidrug transport system, ATPase component	293
650067012	268	26.96	1	267	117	405	7.0e-25	107	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650067014	272	39.53	1	258	1	258	8.0e-53	200	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
650067015	287	39.16	12	274	16	276	7.0e-48	184	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
650067016	366	47.77	7	363	6	352	6.0e-111	394	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
650067017	366	23.13	63	366	1	298	9.0e-29	121	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
650067018	251	34.96	6	249	1	246	2.0e-52	198	COG1414	DNA-binding transcriptional regulator, IclR family	246
650067020	182	24.03	6	151	3	156	4.0e-10	58	COG4512	Accessory gene regulator protein AgrB	198
650067036	147	32.62	10	147	14	152	4.0e-18	83.8	COG2153	Predicted N-acyltransferase, GNAT family	155
650067038	245	17.62	3	221	2	258	5.0e-14	71.6	COG1234	Ribonuclease BN, tRNA processing enzyme	292
650067041	491	35.61	2	486	5	545	0.0e+00	469	COG1982	Arginine/lysine/ornithine decarboxylase	557
650067042	207	48.54	1	206	1	206	8.0e-64	236	COG4493	Uncharacterized protein YktB, UPF0637 family	209
650067044	469	69.15	1	469	1	469	0.0e+00	815	COG0362	6-phosphogluconate dehydrogenase	473
650067046	170	41.67	4	170	1	168	3.0e-39	154	COG0703	Shikimate kinase	172
650067047	102	30.39	2	100	1	102	4.0e-17	79.6	COG0607	Rhodanese-related sulfurtransferase	110
650067048	430	39.53	1	426	3	428	4.0e-104	371	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
650067049	140	62.12	3	132	1	132	3.0e-45	173	COG1832	Predicted CoA-binding protein	140
650067050	627	31.44	1	377	3	387	4.0e-54	206	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
650067051	587	48.68	1	569	2	569	0.0e+00	664	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
650067052	175	33.52	5	172	2	183	1.0e-25	109	COG0693	Putative intracellular protease/amidase	188
650067055	336	42.81	3	335	1	333	8.0e-96	343	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650067056	233	42.17	6	233	5	233	8.0e-53	200	COG0775	Nucleoside phosphorylase	234
650067058	417	38.73	17	417	6	401	1.0e-103	370	COG0162	Tyrosyl-tRNA synthetase	401
650067059	200	53.66	1	200	1	205	2.0e-57	215	COG0522	Ribosomal protein S4 or related protein	205
650067062	371	31.17	3	365	1	385	1.0e-80	293	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
650067063	80	29.23	10	73	22	86	1.0e-04	38.6	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
650067064	95	64.1	13	90	11	88	2.0e-21	94.3	COG4838	Uncharacterized protein YlaN, UPF0358 family	92
650067065	357	37.14	9	355	18	365	6.0e-61	228	COG0387	Ca2+/H+ antiporter	368
650067066	128	46.34	1	122	1	123	3.0e-22	97.6	COG1302	Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family	131
650067067	405	42.82	14	393	15	381	7.0e-83	301	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
650067069	169	24.58	22	139	4	119	5.0e-07	47.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650067070	365	50.14	12	356	12	359	1.0e-110	393	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
650067071	576	36.74	172	574	6	424	1.0e-76	280	COG1061	Superfamily II DNA or RNA helicase	442
650067073	145	30.77	10	126	1	115	1.0e-12	65.7	COG3679	Cell fate regulator YlbF, YheA/YmcA/DUF963 family (controls sporulation, competence, biofilm development)	118
650067074	87	36.47	1	85	2	85	3.0e-14	70.2	COG4471	Uncharacterized protein YlbG, UPF0298 family	90
650067076	298	33	1	298	1	292	6.0e-40	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
650067077	289	39.04	8	256	2	247	1.0e-41	163	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
650067078	929	45.83	1	902	18	904	0.0e+00	882	COG0474	Magnesium-transporting ATPase (P-type)	917
650067079	278	47.5	1	278	1	272	3.0e-85	308	COG0253	Diaminopimelate epimerase	272
650067080	623	39.22	3	287	6	311	8.0e-75	275	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
650067081	295	37.37	1	295	1	290	9.0e-64	237	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
650067082	86	86.05	1	86	1	86	3.0e-33	132	COG2052	Regulator of extracellular matrix RemA, YlzA/DUF370 family	89
650067083	190	54.26	1	188	1	187	9.0e-71	259	COG0194	Guanylate kinase	191
650067084	66	38.1	1	62	1	63	8.0e-10	55.3	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
650067085	417	51.57	1	412	1	391	3.0e-112	398	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
650067086	844	48.48	219	843	133	730	0.0e+00	702	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
650067087	164	47.93	1	164	1	162	2.0e-47	181	COG0242	Peptide deformylase	168
650067088	313	52.9	1	310	2	307	2.0e-112	398	COG0223	Methionyl-tRNA formyltransferase	307
650067089	460	41.06	103	457	1	353	6.0e-99	354	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
650067090	346	48.99	2	344	1	345	1.0e-128	453	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
650067091	258	40.94	1	252	7	259	1.0e-52	200	COG0631	Serine/threonine protein phosphatase PrpC	262
650067092	709	33.89	10	285	2	296	3.0e-46	180	COG0515	Serine/threonine protein kinase	384
650067093	219	61.29	1	217	3	217	5.0e-86	310	COG0036	Pentose-5-phosphate-3-epimerase	220
650067094	62	51.72	1	56	1	58	4.0e-12	63	COG0227	Ribosomal protein L28	77
650067095	592	46.27	2	591	1	542	0.0e+00	567	COG1461	Predicted kinase related to dihydroxyacetone kinase	542
650067096	285	46.21	3	279	2	275	8.0e-72	264	COG1307	Fatty acid-binding protein DegV (function unknown)	282
650067097	683	48.56	1	655	3	661	0.0e+00	797	COG1200	RecG-like helicase	677
650067100	233	46.72	1	227	1	220	3.0e-61	228	COG2135	Putative SOS response-associated peptidase YedK	226
650067101	433	52.78	1	431	9	435	8.0e-106	377	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
650067103	206	35.33	27	205	9	190	1.0e-30	126	COG3554	Uncharacterized protein	190
650067104	149	28.7	32	146	13	127	1.0e-19	89.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650067106	303	19.54	39	299	32	290	8.0e-07	47.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
650067107	305	25.33	9	301	22	313	1.0e-29	123	COG1612	Heme A synthase	323
650067108	297	42.69	6	258	4	245	2.0e-62	232	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
650067109	657	53.75	41	610	1	566	0.0e+00	616	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
650067110	208	44.9	13	207	16	208	2.0e-45	175	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
650067111	107	40.59	2	100	1	101	2.0e-15	74.1	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
650067112	290	41.13	9	290	20	300	6.0e-74	270	COG0109	Polyprenyltransferase (heme O synthase)	304
650067115	186	31.02	1	177	10	193	1.0e-27	116	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650067116	173	27.69	38	152	5	133	3.0e-17	81.8	COG1225	Peroxiredoxin	157
650067117	151	27.71	1	145	5	170	1.0e-13	68.9	COG1495	Disulfide bond formation protein DsbB	170
650067118	49	61.22	1	49	2	50	1.0e-09	54.4	COG0267	Ribosomal protein L33	50
650067120	204	38.8	10	192	5	183	1.0e-34	139	COG3506	Regulation of enolase protein 1 (function unknown), concanavalin A-like superfamily	189
650067121	589	50	1	327	1	322	3.0e-93	336	COG2376	Dihydroxyacetone kinase	323
650067122	305	27.98	65	298	72	312	2.0e-28	120	COG0657	Acetyl esterase/lipase	312
650067127	325	27.25	1	324	2	342	1.0e-42	166	COG0673	Predicted dehydrogenase	342
650067130	326	21.26	16	304	5	279	3.0e-15	76	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
650067131	626	23.71	257	601	2	310	5.0e-17	83.4	COG1482	Mannose-6-phosphate isomerase, class I	312
650067134	302	41	3	299	1	293	3.0e-85	308	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
650067135	320	31.12	1	319	9	339	1.0e-40	160	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
650067136	396	44.84	4	395	6	396	0.0e+00	482	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
650067137	291	40.21	6	288	22	290	9.0e-56	210	COG0010	Arginase family enzyme	305
650067138	453	29.33	6	448	3	433	2.0e-53	203	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067140	274	40.79	2	273	5	281	1.0e-53	203	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650067141	324	37.54	33	324	2	294	2.0e-62	233	COG1175	ABC-type sugar transport system, permease component	295
650067142	327	39.76	2	325	1	332	3.0e-80	292	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650067143	292	40.39	3	292	1	307	5.0e-55	208	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650067144	115	50.85	1	114	18	135	3.0e-34	136	COG1869	D-ribose pyranose/furanose isomerase RbsD	135
650067145	493	54.27	3	492	9	500	0.0e+00	676	COG1129	ABC-type sugar transport system, ATPase component	500
650067146	322	51.6	13	321	2	310	4.0e-65	241	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650067147	358	30.88	10	351	6	339	7.0e-47	181	COG0673	Predicted dehydrogenase	342
650067149	540	23.51	2	528	3	474	8.0e-45	175	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650067150	284	41.75	1	284	25	309	1.0e-77	283	COG4209	ABC-type polysaccharide transport system, permease component	309
650067151	306	29.29	15	305	1	281	2.0e-43	169	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650067152	539	20	63	397	34	351	2.0e-15	77.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067153	244	58.51	4	244	3	241	2.0e-89	321	COG4813	Trehalose utilization protein	261
650067154	351	27.45	1	351	1	342	1.0e-48	186	COG0673	Predicted dehydrogenase	342
650067156	584	46.44	62	580	4	485	0.0e+00	560	COG1492	Cobyric acid synthase	486
650067158	79	35.53	4	77	2	76	1.0e-10	58.1	COG0695	Glutaredoxin	80
650067161	399	26.43	15	394	7	381	1.0e-40	160	COG0754	Glutathionylspermidine synthase	387
650067163	130	26.89	9	127	17	129	2.0e-11	61.4	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
650067166	519	33.08	1	515	2	517	6.0e-107	381	COG1384	Lysyl-tRNA synthetase, class I	521
650067170	455	23.91	1	448	12	427	6.0e-37	148	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650067172	453	44.88	8	432	1	429	0.0e+00	479	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
650067175	429	32.84	225	419	58	257	1.0e-33	137	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650067176	437	38.13	3	431	1	432	2.0e-114	406	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
650067179	496	22.57	66	488	5	438	2.0e-32	133	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650067181	715	29.24	5	696	1	763	2.0e-97	350	COG1511	Uncharacterized membrane protein YhgE, phage infection protein (PIP) family	780
650067185	301	52.56	1	155	19	174	1.0e-57	216	COG0225	Peptide methionine sulfoxide reductase MsrA	174
650067186	205	24.12	5	201	19	217	4.0e-16	78	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
650067187	233	26.12	3	222	11	254	7.0e-31	127	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
650067189	272	30.89	147	269	1	123	2.0e-19	89.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650067190	366	28.86	1	345	1	338	1.0e-48	186	COG0673	Predicted dehydrogenase	342
650067191	361	33.52	2	357	1	338	2.0e-62	233	COG0673	Predicted dehydrogenase	342
650067192	322	24.92	1	313	3	274	4.0e-32	132	COG1082	Sugar phosphate isomerase/epimerase	274
650067193	240	58.97	1	233	2	235	2.0e-93	335	COG4813	Trehalose utilization protein	261
650067194	220	27.62	14	219	17	200	5.0e-22	97.8	COG1573	Uracil-DNA glycosylase	202
650067195	106	44	7	106	8	107	1.0e-25	108	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650067198	241	31.53	19	221	11	212	1.0e-33	136	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650067199	748	61.02	10	745	11	753	0.0e+00	984	COG1882	Pyruvate-formate lyase	755
650067200	242	37.87	1	234	16	247	3.0e-65	241	COG1180	Pyruvate-formate lyase-activating enzyme	260
650067201	450	24.39	3	445	1	429	4.0e-35	142	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067202	294	36.99	1	291	2	293	2.0e-55	209	COG1175	ABC-type sugar transport system, permease component	295
650067203	275	35.87	2	274	7	281	1.0e-48	187	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650067204	618	25.32	143	603	52	451	4.0e-38	153	COG2972	Sensor histidine kinase YesM	456
650067207	156	33.1	1	141	2	145	1.0e-26	112	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
650067208	85	55.56	5	85	7	87	7.0e-27	111	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
650067210	333	38.14	1	332	10	301	5.0e-69	254	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
650067211	249	44.88	10	214	2	205	1.0e-69	256	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
650067212	268	38.64	1	264	5	268	4.0e-34	138	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
650067213	237	37.56	2	215	9	219	4.0e-33	135	COG0785	Cytochrome c biogenesis protein CcdA	220
650067214	141	42.74	1	123	3	126	3.0e-27	113	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
650067215	518	32.66	143	518	28	388	1.0e-68	254	COG1649	Uncharacterized lipoprotein YddW, UPF0748 family	418
650067216	307	27.95	1	282	10	271	3.0e-29	122	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
650067218	330	52.66	1	319	1	314	1.0e-102	366	COG3872	Uncharacterized conserved protein YqhQ	318
650067220	148	60.56	2	143	1	142	2.0e-53	201	COG0757	3-dehydroquinate dehydratase	146
650067221	356	38.4	1	356	9	383	1.0e-89	323	COG0006	Xaa-Pro aminopeptidase	384
650067222	185	46.51	1	129	3	131	6.0e-40	157	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
650067223	417	43.36	1	403	1	447	2.0e-109	389	COG0527	Aspartokinase	447
650067225	332	47.08	6	312	7	293	7.0e-77	281	COG3854	Stage III sporulation protein SpoIIIAA	308
650067233	167	31.87	7	166	1	140	3.0e-22	97.8	COG0511	Biotin carboxyl carrier protein	140
650067234	137	53.17	7	131	2	127	2.0e-26	111	COG1302	Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family	131
650067235	179	22.81	76	169	2	115	6.0e-06	44.1	COG1302	Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family	131
650067237	152	44.59	1	148	8	151	4.0e-32	130	COG0781	Transcription termination factor NusB	151
650067238	286	56.38	5	285	1	282	8.0e-107	380	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
650067239	461	51.83	13	450	4	433	0.0e+00	493	COG1570	Exonuclease VII, large subunit	440
650067240	86	48.48	9	74	11	76	5.0e-09	53	COG1722	Exonuclease VII small subunit	81
650067241	301	42.38	6	270	2	257	1.0e-65	243	COG0142	Geranylgeranyl pyrophosphate synthase	322
650067242	635	56.85	1	625	3	626	0.0e+00	872	COG1154	Deoxyxylulose-5-phosphate synthase	627
650067243	290	59.75	6	246	2	241	4.0e-93	334	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
650067245	149	47.3	1	148	3	150	2.0e-45	175	COG1438	Arginine repressor	150
650067246	579	47.64	1	569	1	557	0.0e+00	552	COG0497	DNA repair ATPase RecN	557
650067249	300	47.06	1	299	1	306	7.0e-99	353	COG4189	Predicted transcriptional regulator	308
650067250	412	24.83	2	406	1	432	8.0e-28	118	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067251	291	33.56	1	289	5	290	1.0e-46	180	COG1175	ABC-type sugar transport system, permease component	295
650067252	304	38.18	29	300	8	279	3.0e-57	215	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650067253	277	24.16	3	242	2	262	6.0e-17	81.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650067257	473	44.95	1	462	1	453	0.0e+00	468	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650067258	346	45.59	10	346	15	353	5.0e-111	394	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
650067259	328	55.25	3	326	1	322	0.0e+00	474	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
650067260	469	37.58	8	460	3	396	3.0e-99	355	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650067261	226	37.17	1	225	7	216	2.0e-47	181	COG0321	Lipoate-protein ligase B	221
650067263	376	24.94	1	376	1	414	1.0e-60	227	COG2195	Di- or tripeptidase	414
650067266	189	27.78	52	180	9	150	9.0e-09	53.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
650067267	404	37.31	14	402	1	381	7.0e-92	331	COG1379	PHP family phosphoesterase with a Zn ribbon	403
650067268	207	26.56	9	200	14	200	1.0e-11	63.4	COG1300	Uncharacterized membrane protein SpoIIM, required for sporulation	207
650067269	154	40.27	1	149	1	145	1.0e-33	135	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
650067271	294	44.75	1	293	5	299	2.0e-87	315	COG4974	Site-specific recombinase XerD	300
650067272	274	43.87	9	274	2	262	7.0e-74	270	COG0005	Purine nucleoside phosphorylase	262
650067273	396	36.78	1	394	2	386	2.0e-93	335	COG1686	D-alanyl-D-alanine carboxypeptidase	389
650067274	117	35.92	11	113	12	114	4.0e-16	76.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
650067275	152	34.07	13	143	8	142	2.0e-27	114	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
650067276	251	40	8	249	1	244	3.0e-54	205	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
650067280	443	41.13	5	409	1	394	3.0e-113	402	COG0019	Diaminopimelate decarboxylase	394
650067281	143	47.73	14	140	10	141	3.0e-42	163	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
650067282	147	36.64	15	145	2	131	1.0e-26	112	COG0824	Acyl-CoA thioesterase FadM	137
650067283	366	48.64	147	363	1	216	8.0e-59	221	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
650067284	222	53	1	200	1	198	6.0e-68	250	COG0307	Riboflavin synthase alpha chain	204
650067285	412	61.08	5	207	1	203	2.0e-84	306	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
650067286	155	64.67	3	152	2	151	5.0e-57	213	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
650067287	263	39.92	1	251	2	242	8.0e-37	147	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
650067288	201	42.39	1	183	3	184	2.0e-42	165	COG1386	Chromosome segregation and condensation protein ScpB	184
650067290	147	46.72	1	137	1	121	1.0e-32	132	COG3874	Uncharacterized spore protein YtfJ	138
650067291	394	35.54	6	370	3	372	7.0e-75	274	COG1686	D-alanyl-D-alanine carboxypeptidase	389
650067292	210	54.31	1	197	1	197	1.0e-65	242	COG2715	Spore maturation protein SpmA (function unknown)	206
650067293	177	48.15	16	177	1	162	2.0e-40	158	COG0700	Spore maturation protein SpmB (function unknown)	162
650067295	251	49.39	1	239	2	246	3.0e-78	285	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
650067297	139	27.69	2	118	7	135	1.0e-15	75.7	COG1225	Peroxiredoxin	157
650067298	567	26.14	73	563	1	473	6.0e-75	275	COG1333	Cytochrome c biogenesis protein ResB	478
650067299	417	30.34	185	415	61	281	3.0e-23	103	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
650067300	238	50	7	238	2	229	3.0e-67	248	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067301	477	31.36	27	471	11	447	6.0e-72	265	COG5002	Signal transduction histidine kinase	459
650067302	530	50	1	323	3	323	3.0e-97	349	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650067303	199	26.52	20	188	38	218	2.0e-05	43	COG1266	Membrane protease YdiL, CAAX protease family	226
650067305	272	26.44	1	271	1	284	2.0e-28	119	COG1408	Predicted phosphohydrolase, MPP superfamily	284
650067306	303	33.66	106	303	58	261	3.0e-32	132	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650067308	203	31.7	1	199	1	222	1.0e-31	129	COG4862	Negative regulator of genetic competence, sporulation and motility	224
650067309	231	34.33	1	219	38	270	2.0e-25	109	COG2339	Membrane proteinase PrsW, cleaves anti-sigma factor RsiW, M82 family	274
650067312	217	24.89	5	217	10	229	2.0e-15	75.7	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
650067314	226	47.51	9	226	2	219	9.0e-69	253	COG0283	Cytidylate kinase	222
650067315	196	35.45	1	177	32	220	2.0e-26	112	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
650067316	405	41.33	5	395	1	385	7.0e-93	334	COG0539	Ribosomal protein S1	541
650067317	440	60.23	1	438	1	440	0.0e+00	602	COG1160	Predicted GTPases	444
650067318	208	41.71	1	195	2	200	3.0e-41	161	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
650067319	346	54.41	4	332	3	329	7.0e-121	427	COG0240	Glycerol-3-phosphate dehydrogenase	329
650067326	90	64.44	1	90	2	91	2.0e-29	120	COG0776	Bacterial nucleoid DNA-binding protein	94
650067329	320	30.28	3	318	8	303	3.0e-48	185	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
650067332	252	44.54	12	248	2	238	9.0e-75	273	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
650067333	290	35.31	1	286	6	289	2.0e-39	156	COG0382	4-hydroxybenzoate polyprenyltransferase	289
650067334	200	55.38	5	199	1	187	3.0e-70	257	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
650067335	287	34.6	8	270	4	249	2.0e-43	169	COG1427	Predicted periplasmic solute-binding protein	252
650067336	324	39.14	5	324	2	322	8.0e-71	260	COG0142	Geranylgeranyl pyrophosphate synthase	322
650067337	147	60.45	1	134	2	135	3.0e-55	207	COG0105	Nucleoside diphosphate kinase	135
650067338	267	42.48	10	266	1	266	2.0e-70	259	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
650067340	339	46.55	1	332	57	368	1.0e-106	380	COG0082	Chorismate synthase	369
650067341	364	49.04	1	363	1	360	3.0e-116	412	COG0337	3-dehydroquinate synthetase	360
650067342	124	57.5	1	120	1	120	3.0e-39	153	COG4401	Chorismate mutase	125
650067343	517	48.45	20	497	1	461	0.0e+00	517	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
650067344	346	49.7	4	341	1	338	4.0e-114	404	COG0547	Anthranilate phosphoribosyltransferase	338
650067345	269	50	3	258	1	252	5.0e-81	294	COG0134	Indole-3-glycerol phosphate synthase	254
650067346	205	43.07	4	204	21	207	5.0e-47	180	COG0135	Phosphoribosylanthranilate isomerase	208
650067347	398	67.68	3	398	1	395	0.0e+00	678	COG0133	Tryptophan synthase beta chain	396
650067348	268	44.98	1	268	1	261	2.0e-82	298	COG0159	Tryptophan synthase alpha chain	265
650067349	365	40.72	3	358	2	352	9.0e-92	330	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
650067350	362	36.07	1	278	4	276	2.0e-62	233	COG0287	Prephenate dehydrogenase	279
650067351	197	36.46	2	181	1	177	5.0e-29	120	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650067353	195	36.92	1	183	3	196	2.0e-32	132	COG0406	Broad specificity phosphatase PhoE	208
650067358	181	26.9	19	180	7	173	3.0e-21	94.9	COG0723	Rieske Fe-S protein	177
650067361	210	41.15	1	192	1	179	2.0e-31	129	COG4347	Uncharacterized membrane protein YpjA	200
650067363	123	27.27	14	123	2	102	2.0e-14	71.6	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
650067365	267	40.96	3	267	1	265	1.0e-68	253	COG0289	Dihydrodipicolinate reductase	266
650067366	139	54.48	1	134	5	138	2.0e-51	195	COG1803	Methylglyoxal synthase	142
650067367	235	34.27	1	204	7	213	2.0e-31	129	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
650067368	387	28.31	8	378	6	381	3.0e-40	159	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650067369	434	32.45	24	432	14	412	1.0e-63	237	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
650067370	311	42.47	90	307	1	216	2.0e-55	209	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
650067371	293	57.3	8	274	3	268	4.0e-103	367	COG0413	Ketopantoate hydroxymethyltransferase	268
650067372	296	49.32	1	290	1	285	1.0e-99	356	COG0414	Panthothenate synthetase	285
650067373	127	69.05	2	127	1	126	2.0e-48	184	COG0853	Aspartate 1-decarboxylase	126
650067375	961	32.48	252	945	5	651	6.0e-110	392	COG1199	Rad3-related DNA helicase	654
650067376	221	44.33	5	207	6	208	5.0e-59	220	COG2344	NADH/NAD ratio-sensing transcriptional regulator Rex	211
650067377	433	40.29	7	409	4	411	9.0e-88	317	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
650067378	172	21.25	2	160	3	152	9.0e-13	66.6	COG5353	Uncharacterized protein YpmB	161
650067380	500	40.86	17	499	95	594	9.0e-103	367	COG0465	ATP-dependent Zn proteases	596
650067381	290	44.33	1	290	1	290	2.0e-79	289	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650067382	402	57.64	1	399	1	395	0.0e+00	565	COG0282	Acetate kinase	396
650067383	431	52.4	1	431	1	435	0.0e+00	565	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
650067384	268	29.82	21	248	10	212	5.0e-33	134	COG3935	DNA replication protein DnaD	246
650067385	229	30.3	1	228	2	225	3.0e-30	125	COG1011	FMN phosphatase YigB, HAD superfamily	229
650067389	336	24.12	48	291	41	283	5.0e-26	111	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
650067390	203	32.79	21	202	1	180	8.0e-27	113	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650067396	218	32.35	12	214	6	196	4.0e-27	115	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650067397	226	32.42	6	224	2	218	1.0e-43	169	COG4359	2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase (methionine salvage)	220
650067398	404	37.5	1	401	19	424	6.0e-102	364	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
650067399	289	43.07	15	281	4	264	1.0e-68	253	COG0345	Pyrroline-5-carboxylate reductase	266
650067400	415	57.93	1	415	2	417	0.0e+00	585	COG0014	Gamma-glutamyl phosphate reductase	417
650067401	367	51.1	4	366	8	369	3.0e-123	435	COG0263	Glutamate 5-kinase	369
650067402	397	39.02	15	393	3	388	3.0e-99	355	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650067403	270	41.7	9	270	3	269	4.0e-60	224	COG0388	Predicted amidohydrolase	274
650067405	310	33.89	1	299	1	291	2.0e-44	173	COG0583	DNA-binding transcriptional regulator, LysR family	297
650067406	488	58.33	16	479	1	422	0.0e+00	629	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
650067407	175	53.66	1	164	1	156	1.0e-60	225	COG0066	3-isopropylmalate dehydratase small subunit	191
650067409	525	37.23	305	522	2	228	1.0e-49	191	COG0860	N-acetylmuramoyl-L-alanine amidase	231
650067411	461	39.57	243	458	2	228	3.0e-53	203	COG0860	N-acetylmuramoyl-L-alanine amidase	231
650067414	228	54.72	1	212	1	211	6.0e-79	287	COG0177	Endonuclease III	211
650067416	589	38.19	43	571	1	518	6.0e-122	431	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650067418	153	25.49	7	150	7	157	1.0e-08	52.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650067420	283	25.23	73	281	10	207	5.0e-16	78.4	COG2755	Lysophospholipase L1 or related esterase	216
650067421	322	36.19	9	318	4	293	2.0e-70	259	COG1131	ABC-type multidrug transport system, ATPase component	293
650067422	329	20.74	114	328	65	278	2.0e-13	69.8	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
650067423	659	57.36	17	659	1	634	0.0e+00	877	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
650067424	819	48.01	3	807	4	797	0.0e+00	896	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
650067425	143	38.32	29	134	20	126	4.0e-10	57.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
650067426	244	31.82	10	224	76	289	3.0e-40	158	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
650067428	172	41.67	1	168	4	168	2.0e-37	148	COG3153	Predicted N-acetyltransferase YhbS	171
650067430	599	35.28	4	597	1	595	0.0e+00	461	COG1164	Oligoendopeptidase F	598
650067432	93	39.08	1	87	6	92	7.0e-19	85.4	COG2388	Predicted acetyltransferase, GNAT superfamily	99
650067434	151	18.05	7	124	5	137	5.0e-05	40.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650067435	198	24.04	1	182	3	185	8.0e-13	67.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650067436	313	32.29	1	306	1	305	2.0e-52	199	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650067437	279	31.43	171	275	17	120	2.0e-17	83	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650067442	461	31.28	24	459	16	449	2.0e-46	180	COG0534	Na+-driven multidrug efflux pump	455
650067443	86	40.48	1	84	5	87	8.0e-16	75.3	COG1937	DNA-binding transcriptional regulator, FrmR family	89
650067444	75	47.37	1	75	2	77	2.0e-19	87.2	COG0425	TusA-related sulfurtransferase	78
650067445	161	41.88	4	161	2	137	3.0e-34	137	COG2210	Peroxiredoxin family protein	137
650067446	119	35.05	26	119	4	100	6.0e-18	83	COG0607	Rhodanese-related sulfurtransferase	110
650067447	98	33.33	1	98	3	104	4.0e-15	73	COG0607	Rhodanese-related sulfurtransferase	110
650067448	191	40.82	95	189	9	106	2.0e-15	76.1	COG0607	Rhodanese-related sulfurtransferase	110
650067449	375	26.84	130	295	25	211	2.0e-17	83.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650067450	260	28.24	2	260	1	255	2.0e-08	53.1	COG0730	Uncharacterized membrane protein YfcA	258
650067451	641	29.55	96	628	1	515	1.0e-65	244	COG1657	Squalene cyclase	517
650067453	267	33.33	136	261	1	126	4.0e-21	95.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650067454	490	23.89	1	432	5	462	1.0e-46	181	COG3119	Arylsulfatase A or related enzyme	475
650067457	268	36.08	8	260	1	253	6.0e-51	194	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650067458	335	25.95	36	295	47	293	4.0e-21	95.8	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
650067460	263	35.94	1	254	4	258	6.0e-51	194	COG2116	Formate/nitrite transporter FocA, FNT family	265
650067461	175	38.89	1	175	1	180	3.0e-29	121	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650067462	325	28.53	12	325	3	314	1.0e-35	144	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650067464	423	33.33	62	160	26	124	1.0e-20	94.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650067465	612	34.51	1	473	1	457	2.0e-117	416	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
650067466	463	25.8	186	461	29	298	4.0e-34	139	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
650067472	170	22	6	105	38	137	2.0e-10	59.1	COG1695	DNA-binding transcriptional regulator, PadR family	138
650067473	189	28.72	5	183	4	196	6.0e-31	127	COG0288	Carbonic anhydrase	207
650067475	505	49.6	3	501	1	497	0.0e+00	600	COG2317	Zn-dependent carboxypeptidase, M32 family	497
650067476	334	25.89	1	334	1	332	5.0e-39	155	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650067477	240	45.7	3	223	2	218	9.0e-74	270	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650067478	277	30.92	26	274	3	251	2.0e-48	186	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650067479	326	26.77	2	310	10	318	8.0e-39	154	COG4129	Uncharacterized membrane protein YgaE, UPF0421/DUF939 family	332
650067483	924	48.38	1	821	3	824	0.0e+00	869	COG0249	DNA mismatch repair ATPase MutS	843
650067484	660	39.22	1	659	1	638	0.0e+00	612	COG0323	DNA mismatch repair ATPase MutL	638
650067485	315	46.77	5	313	1	308	2.0e-97	349	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
650067486	79	51.32	1	76	1	76	1.0e-23	101	COG1923	sRNA-binding regulator protein Hfq	77
650067487	886	37.34	24	654	1	615	0.0e+00	501	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
650067488	185	27.61	1	163	1	162	4.0e-22	97.8	COG2306	Predicted RNA-binding protein, associated with RNAse of E/G family	183
650067489	217	25.12	13	208	7	206	4.0e-16	78.4	COG2949	Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin	235
650067491	429	52.32	13	417	3	405	9.0e-122	430	COG2262	50S ribosomal subunit-associated GTPase HflX	411
650067492	417	59.07	6	413	9	416	0.0e+00	579	COG4100	Cystathionine beta-lyase family protein involved in aluminum resistance	416
650067493	136	31.73	12	114	1	104	9.0e-14	69.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
650067494	442	51.24	3	439	1	441	0.0e+00	569	COG0174	Glutamine synthetase	443
650067496	179	28.49	6	174	6	177	7.0e-28	116	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650067498	208	49.76	1	208	1	201	5.0e-59	220	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
650067502	263	32.45	1	263	2	229	1.0e-28	120	COG1011	FMN phosphatase YigB, HAD superfamily	229
650067504	178	36.69	1	169	1	160	1.0e-31	129	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
650067505	1146	42.67	310	1143	4	842	0.0e+00	875	COG1410	Methionine synthase I, cobalamin-binding domain	842
650067506	309	51.96	1	305	2	291	2.0e-78	286	COG1234	Ribonuclease BN, tRNA processing enzyme	292
650067507	263	39.7	1	262	4	266	2.0e-66	245	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
650067508	272	36.86	1	270	1	273	5.0e-58	217	COG0266	Formamidopyrimidine-DNA glycosylase	273
650067509	282	30.53	4	280	1	273	5.0e-40	158	COG0648	Endonuclease IV	280
650067514	358	28.76	79	355	65	352	3.0e-22	99.6	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
650067515	489	27.49	18	273	2	288	3.0e-30	126	COG0515	Serine/threonine protein kinase	384
650067518	289	18.56	1	254	2	245	7.0e-04	38.2	COG1192	Cellulose biosynthesis protein BcsQ	259
650067519	637	24.82	269	539	65	332	3.0e-10	60.7	COG4962	Pilus assembly protein, ATPase of CpaF family	355
650067525	517	43.08	1	511	1	511	0.0e+00	499	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650067526	376	42.63	35	280	6	254	1.0e-56	214	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
650067528	239	39.73	5	224	3	225	2.0e-42	166	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067530	214	36.45	4	214	2	211	2.0e-40	159	COG1564	Thiamine pyrophosphokinase	212
650067531	217	41.38	3	201	3	204	5.0e-41	161	COG2860	Uncharacterized membrane protein YeiH	209
650067532	242	35.59	9	242	66	297	4.0e-44	171	COG2382	Enterochelin esterase or related enzyme	299
650067533	375	42.61	38	375	6	357	4.0e-103	368	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
650067534	325	59.57	3	325	1	324	0.0e+00	478	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
650067535	439	46	2	438	1	404	3.0e-107	382	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650067536	471	51.99	11	458	6	454	0.0e+00	504	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650067537	264	68.8	1	264	3	268	5.0e-118	417	COG0207	Thymidylate synthase	268
650067538	164	40	1	162	1	167	3.0e-38	151	COG0262	Dihydrofolate reductase	167
650067539	495	42.95	22	491	1	453	0.0e+00	491	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
650067540	761	31.02	2	607	1	554	9.0e-119	421	COG0550	DNA topoisomerase IA	570
650067541	245	18.88	3	242	2	228	6.0e-14	71.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
650067543	393	23.73	15	378	16	385	2.0e-11	64.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650067547	225	40	3	206	2	204	1.0e-52	199	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067548	484	33.44	147	467	17	335	9.0e-49	188	COG0642	Signal transduction histidine kinase	336
650067551	377	53.2	1	354	1	356	9.0e-123	433	COG0448	ADP-glucose pyrophosphorylase	393
650067552	657	49.12	10	626	6	624	0.0e+00	687	COG0296	1,4-alpha-glucan branching enzyme	628
650067553	582	28.99	131	543	1	494	3.0e-54	206	COG0366	Glycosidase	505
650067554	480	48.36	267	478	10	222	3.0e-67	249	COG0765	ABC-type amino acid transport system, permease component	222
650067557	242	39.42	138	240	16	109	1.0e-12	67.3	COG3584	3D (Asp-Asp-Asp) domain	109
650067558	282	45.64	87	276	65	257	4.0e-42	165	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650067559	340	46.59	1	327	3	336	1.0e-95	343	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650067560	222	41.1	1	218	1	219	5.0e-21	94.6	COG1842	Phage shock protein A	225
650067561	134	21.97	3	134	5	131	1.0e-08	52.2	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
650067565	428	41.06	14	426	1	404	3.0e-102	365	COG0303	Molybdopterin biosynthesis enzyme	404
650067566	167	37.5	1	166	2	161	4.0e-33	134	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
650067567	360	27.81	15	346	1	285	2.0e-33	136	COG4974	Site-specific recombinase XerD	300
650067568	167	33.58	26	161	1	135	2.0e-17	82.3	COG5628	Predicted acetyltransferase	143
650067569	443	22.1	6	443	2	431	3.0e-26	113	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067570	285	34.49	1	282	5	291	6.0e-44	171	COG1175	ABC-type sugar transport system, permease component	295
650067571	290	39.78	15	289	3	281	2.0e-56	212	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650067575	145	28.1	19	135	3	123	9.0e-11	59.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
650067576	211	52.34	1	209	1	211	3.0e-66	244	COG2910	Putative NADH-flavin reductase	211
650067581	249	38.04	1	242	1	251	9.0e-46	176	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650067583	525	19.02	38	443	33	408	1.0e-11	65.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067584	293	31.86	3	292	1	281	2.0e-48	186	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650067585	212	33.05	11	124	10	127	1.0e-18	86.6	COG2372	Copper-binding protein CopC (methionine-rich)	127
650067586	362	21.86	11	278	10	288	1.0e-13	71.5	COG1276	Putative copper export protein	289
650067589	213	48.08	3	210	1	208	3.0e-53	201	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650067590	272	32.92	1	221	1	240	2.0e-27	116	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
650067598	196	28.14	22	188	18	181	2.0e-20	92.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650067599	409	46.06	7	409	3	385	2.0e-110	393	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
650067600	410	46.57	5	409	1	385	6.0e-108	384	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
650067602	450	32.01	41	446	86	499	3.0e-56	213	COG0168	Trk-type K+ transport system, membrane component	499
650067603	378	36.65	1	378	2	350	2.0e-76	279	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650067604	241	41.94	15	231	10	226	3.0e-42	165	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
650067605	108	39.22	7	108	6	107	2.0e-11	61	COG4392	Branched-chain amino acid transport protein	107
650067607	443	25.16	28	330	27	325	3.0e-25	110	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650067610	355	18.96	1	353	1	377	8.0e-20	91.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650067611	305	37.82	1	304	1	311	8.0e-61	227	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650067612	641	25.51	14	631	29	632	2.0e-72	267	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
650067613	331	43.96	10	328	1	321	3.0e-92	332	COG0502	Biotin synthase or related enzyme	335
650067614	101	32.22	1	86	6	93	8.0e-05	38.8	COG0607	Rhodanese-related sulfurtransferase	110
650067616	416	26.83	1	322	1	284	1.0e-38	154	COG2404	Oligoribonuclease NrnB or cAMP/cGMP phosphodiesterase, DHH superfamily	339
650067618	95	18.07	9	89	19	101	9.0e-05	38.7	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
650067619	198	45.18	3	198	15	209	1.0e-37	150	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
650067620	647	54.66	35	600	1	566	0.0e+00	590	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
650067621	334	43.1	7	245	1	233	2.0e-53	202	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
650067623	481	35.43	11	480	1	456	3.0e-110	392	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650067624	206	36.45	1	200	1	200	1.0e-43	169	COG1279	Arginine exporter protein ArgO	202
650067626	270	22.77	52	251	39	262	4.0e-05	42.1	COG1082	Sugar phosphate isomerase/epimerase	274
650067629	306	28.24	1	241	1	241	4.0e-36	145	COG1876	LD-carboxypeptidase LdcB, LAS superfamily	241
650067633	303	24.03	11	303	7	307	4.0e-20	92	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
650067636	178	48.04	2	177	1	169	1.0e-42	166	COG4675	Microcystin-dependent protein  (function unknown)	170
650067637	165	51.18	2	165	1	170	1.0e-42	165	COG4675	Microcystin-dependent protein  (function unknown)	170
650067638	169	44.71	2	169	1	170	2.0e-42	165	COG4675	Microcystin-dependent protein  (function unknown)	170
650067643	316	32.38	10	313	11	314	9.0e-33	134	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
650067646	83	35.62	1	71	1	73	4.0e-11	59.9	COG3655	DNA-binding transcriptional regulator, XRE family	73
650067650	153	20.31	31	153	35	162	2.0e-04	38.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650067660	174	25	1	164	20	199	3.0e-18	85.1	COG3896	Chloramphenicol 3-O-phosphotransferase	205
650067664	151	27.52	13	113	7	115	1.0e-08	52.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650067667	194	30.94	7	141	5	142	6.0e-13	67.7	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
650067670	232	39.39	4	232	2	229	9.0e-62	230	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067671	307	26.8	1	305	39	329	8.0e-35	141	COG0642	Signal transduction histidine kinase	336
650067672	307	38.94	5	303	4	293	2.0e-66	246	COG1131	ABC-type multidrug transport system, ATPase component	293
650067677	133	43.28	3	132	2	135	7.0e-27	113	COG3981	Predicted acetyltransferase	174
650067680	182	37.14	6	174	9	182	2.0e-26	112	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650067682	143	20.61	1	131	1	118	3.0e-07	47.9	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
650067684	222	28.76	1	217	3	227	8.0e-26	110	COG1011	FMN phosphatase YigB, HAD superfamily	229
650067686	202	43.54	50	194	43	189	9.0e-33	133	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
650067688	648	30.6	1	633	7	696	1.0e-117	417	COG0480	Translation elongation factor EF-G, a GTPase	697
650067690	672	29.34	410	667	2	251	1.0e-20	95.6	COG0642	Signal transduction histidine kinase	336
650067691	522	41.88	398	513	2	116	5.0e-21	96.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
650067695	181	18	4	180	83	282	6.0e-12	64	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650067697	162	39.02	2	162	10	173	3.0e-24	104	COG0290	Translation initiation factor IF-3	176
650067698	572	30.35	40	543	10	472	5.0e-82	299	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
650067699	287	22.14	26	285	5	232	4.0e-16	79.1	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
650067700	141	30.71	4	141	7	146	4.0e-14	70.6	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
650067701	233	26.17	9	220	1	214	5.0e-23	101	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650067702	152	31.29	1	145	3	149	1.0e-12	66	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
650067704	413	18.31	44	406	50	390	2.0e-08	54.4	COG2814	Predicted arabinose efflux permease, MFS family	394
650067705	150	38.52	25	144	2	122	3.0e-10	58	COG4270	Uncharacterized membrane protein	131
650067706	208	21.71	1	175	4	177	2.0e-11	62.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650067707	153	31.29	6	152	8	153	6.0e-12	63.4	COG5528	Uncharacterized membrane protein	155
650067710	411	21.34	36	349	37	339	1.0e-19	91.4	COG2814	Predicted arabinose efflux permease, MFS family	394
650067717	196	35.6	1	184	2	188	1.0e-23	103	COG0693	Putative intracellular protease/amidase	188
650067718	174	25.93	20	150	1	120	5.0e-12	64.2	COG5628	Predicted acetyltransferase	143
650067719	157	35.85	37	142	16	121	9.0e-11	59.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
650067720	457	21.61	13	407	13	363	3.0e-14	73.3	COG2814	Predicted arabinose efflux permease, MFS family	394
650067721	183	36.59	20	180	16	179	8.0e-25	106	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650067724	502	27.78	5	180	3	182	2.0e-25	111	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650067727	549	71.9	2	548	5	550	0.0e+00	837	COG3573	Predicted oxidoreductase	552
650067729	442	19.79	60	437	39	394	2.0e-07	51	COG2814	Predicted arabinose efflux permease, MFS family	394
650067730	305	46.69	1	305	1	298	9.0e-114	403	COG4989	Predicted oxidoreductase	298
650067732	305	31.72	5	301	3	305	4.0e-48	185	COG0492	Thioredoxin reductase	305
650067733	578	39.62	6	578	5	567	0.0e+00	466	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650067734	274	34.23	3	252	11	249	1.0e-38	153	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
650067737	197	23.33	17	186	3	182	6.0e-22	97.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650067739	162	25	3	162	21	178	2.0e-18	85.5	COG0431	NAD(P)H-dependent FMN reductase	184
650067741	392	28.24	17	392	15	389	1.0e-64	240	COG4552	Predicted acetyltransferase	389
650067744	635	54.49	36	635	2	584	0.0e+00	746	COG0441	Threonyl-tRNA synthetase	589
650067749	261	32.38	7	111	2	106	1.0e-14	74	COG0789	DNA-binding transcriptional regulator, MerR family	124
650067751	315	25.76	2	315	1	315	8.0e-36	144	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650067754	613	26.2	18	376	1	327	3.0e-43	170	COG3469	Chitinase	332
650067755	567	39.79	1	552	5	563	3.0e-127	449	COG0443	Molecular chaperone DnaK (HSP70)	579
650067759	762	57.27	426	755	1	328	8.0e-120	425	COG0620	Methionine synthase II (cobalamin-independent)	330
650067760	476	34.7	33	238	11	228	1.0e-47	184	COG0860	N-acetylmuramoyl-L-alanine amidase	231
650067761	232	45.92	5	231	2	229	2.0e-57	215	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067762	484	27.09	138	483	6	334	3.0e-39	156	COG0642	Signal transduction histidine kinase	336
650067764	402	18.69	44	359	17	340	2.0e-21	97	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067766	293	35.07	10	290	5	292	2.0e-44	173	COG1175	ABC-type sugar transport system, permease component	295
650067767	292	34.59	6	291	8	281	7.0e-49	187	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650067770	536	42.08	7	536	1	539	0.0e+00	542	COG0405	Gamma-glutamyltranspeptidase	539
650067774	201	31.43	20	190	8	182	3.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650067776	571	31.86	342	567	1	181	9.0e-36	145	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
650067778	164	31.43	29	133	9	113	8.0e-10	56.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
650067780	590	32.27	200	573	48	405	9.0e-40	158	COG0840	Methyl-accepting chemotaxis protein	408
650067784	313	49.67	8	313	5	309	2.0e-106	379	COG2066	Glutaminase	309
650067786	255	47.53	4	225	1	223	1.0e-77	283	COG1136	ABC-type lipoprotein export system, ATPase component	226
650067788	121	38.14	1	117	1	113	4.0e-16	76.9	COG5294	Uncharacterized protein YxeA	113
650067790	235	40.26	6	234	2	229	4.0e-60	224	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067791	470	30.07	166	470	36	327	7.0e-34	138	COG0642	Signal transduction histidine kinase	336
650067792	218	41.67	3	218	1	227	1.0e-54	206	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067795	296	36.77	12	295	3	293	4.0e-46	178	COG1175	ABC-type sugar transport system, permease component	295
650067796	308	33.11	9	307	2	281	7.0e-51	194	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650067797	376	19.79	1	370	16	368	1.0e-13	71.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650067800	464	19.74	9	458	4	426	2.0e-21	97.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067803	453	25.46	16	441	14	442	1.0e-45	177	COG0534	Na+-driven multidrug efflux pump	455
650067804	192	24.56	4	174	15	179	3.0e-10	58.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650067807	334	42.25	9	331	4	330	2.0e-52	199	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
650067808	340	42.9	11	340	1	330	2.0e-54	206	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
650067809	282	26.26	8	282	5	272	5.0e-24	104	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650067810	250	36	25	224	18	217	5.0e-41	161	COG4619	ABC-type iron transport system FetAB, ATPase component	223
650067812	794	32.31	504	760	3	253	2.0e-42	168	COG0142	Geranylgeranyl pyrophosphate synthase	322
650067817	361	35.36	4	352	1	333	8.0e-68	250	COG0136	Aspartate-semialdehyde dehydrogenase	334
650067818	458	30.51	5	446	18	462	3.0e-61	229	COG1757	Na+/H+ antiporter NhaC	485
650067822	475	29.72	9	470	20	487	9.0e-94	337	COG2368	Aromatic ring hydroxylase	493
650067823	264	35.15	57	257	41	241	3.0e-40	158	COG1876	LD-carboxypeptidase LdcB, LAS superfamily	241
650067825	408	26.41	29	404	19	397	3.0e-29	123	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
650067827	231	40.79	4	229	2	225	4.0e-63	234	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067829	570	42.34	15	529	1	496	1.0e-111	397	COG0366	Glycosidase	505
650067830	673	37.37	96	479	1	388	3.0e-81	296	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
650067831	245	30.3	4	234	7	236	7.0e-47	180	COG2188	DNA-binding transcriptional regulator, GntR family	236
650067832	260	36.82	3	255	1	249	8.0e-43	167	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650067833	325	25.24	6	309	7	297	2.0e-21	96.9	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
650067835	258	57.54	1	251	68	316	4.0e-99	354	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650067836	332	55.13	2	313	1	265	3.0e-109	388	COG4608	ABC-type oligopeptide transport system, ATPase component	309
650067837	554	39.53	34	554	20	553	2.0e-102	366	COG0747	ABC-type transport system, periplasmic component	556
650067838	334	47.31	1	334	1	316	3.0e-98	351	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650067839	298	54.48	22	298	10	288	2.0e-79	289	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650067841	360	32.13	2	360	1	341	2.0e-60	226	COG0673	Predicted dehydrogenase	342
650067844	298	30.83	175	294	8	127	9.0e-23	101	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650067845	439	22.09	87	397	2	293	4.0e-10	60	COG1397	ADP-ribosylglycohydrolase	314
650067846	268	21.34	4	224	7	229	2.0e-15	76.9	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
650067847	269	26.98	143	268	2	127	4.0e-19	88.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650067848	301	19.19	6	297	9	293	6.0e-06	45.1	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
650067849	319	43.69	11	319	1	309	1.0e-92	333	COG4209	ABC-type polysaccharide transport system, permease component	309
650067850	531	21.59	2	449	1	417	4.0e-20	93.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067851	375	30.93	37	369	21	333	3.0e-53	202	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650067853	601	32.57	35	332	48	328	7.0e-29	122	COG3344	Retron-type reverse transcriptase	328
650067855	462	18.67	22	438	2	477	4.0e-20	92.8	COG1233	Phytoene dehydrogenase-related protein	487
650067856	270	27.15	3	151	33	182	2.0e-19	89.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650067863	385	31.27	10	372	2	355	5.0e-72	265	COG3424	Predicted naringenin-chalcone synthase	356
650067865	383	24.15	2	366	1	358	7.0e-29	121	COG0644	Dehydrogenase (flavoprotein)	396
650067868	148	30	27	145	23	135	6.0e-12	63.5	COG1765	Uncharacterized OsmC-related protein	137
650067869	131	60	1	126	1	130	3.0e-39	153	COG1970	Large-conductance mechanosensitive channel	130
650067875	125	43.27	16	119	12	114	2.0e-24	104	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650067876	182	35.57	1	179	1	187	5.0e-32	130	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
650067877	224	46.7	2	221	1	226	9.0e-60	223	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067878	457	36.57	150	455	34	333	2.0e-45	176	COG0642	Signal transduction histidine kinase	336
650067879	326	15.52	62	322	5	279	3.0e-13	69.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650067883	383	33.63	19	359	1	335	1.0e-42	167	COG0628	Predicted PurR-regulated permease PerM	355
650067884	276	31.03	2	114	1	115	7.0e-16	77.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
650067885	341	26.16	42	318	64	361	1.0e-29	123	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650067887	315	33.23	1	315	4	309	4.0e-46	178	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650067888	409	36.96	43	406	49	408	2.0e-67	250	COG2124	Cytochrome P450	411
650067891	195	56.78	1	195	1	199	3.0e-63	234	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
650067892	123	52.03	1	123	1	123	4.0e-40	156	COG5646	Uncharacterized conserved protein YdhG, YjbR/CyaY-like superfamily, DUF1801 family	126
650067894	340	34.99	3	340	2	329	5.0e-65	241	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650067899	308	42.62	12	308	16	309	1.0e-75	276	COG4209	ABC-type polysaccharide transport system, permease component	309
650067900	298	29.62	16	297	13	281	5.0e-38	151	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650067901	486	20.88	4	361	2	349	3.0e-16	80.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650067903	231	41.67	5	230	2	226	2.0e-58	219	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067904	190	29.51	9	189	10	192	3.0e-29	121	COG3963	Phospholipid N-methyltransferase	194
650067906	213	34.16	12	211	11	212	5.0e-40	157	COG2345	Predicted transcriptional regulator, ArsR family	218
650067911	308	38.33	181	300	8	127	1.0e-20	94.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650067912	327	40.82	1	311	1	312	2.0e-85	309	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650067914	323	29.1	8	300	1	298	5.0e-48	185	COG0657	Acetyl esterase/lipase	312
650067915	326	43.12	1	324	1	315	5.0e-91	327	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650067917	274	32	47	271	14	225	3.0e-21	95.8	COG2801	Transposase InsO and inactivated derivatives	232
650067920	181	33.33	3	94	1	93	1.0e-08	53.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
650067921	297	23.26	67	279	30	213	7.0e-10	57.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650067923	285	20.14	1	283	39	298	5.0e-13	68.5	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
650067925	234	19.03	7	222	9	228	3.0e-11	62.2	COG1018	Ferredoxin-NADP reductase	266
650067926	273	28.25	1	268	1	264	6.0e-41	161	COG0300	Short-chain dehydrogenase	265
650067927	189	27.59	1	145	3	147	8.0e-14	70.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650067928	192	32.22	1	172	20	199	1.0e-25	109	COG3896	Chloramphenicol 3-O-phosphotransferase	205
650067931	529	33.33	7	500	25	517	7.0e-85	308	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
650067932	268	35.82	1	267	18	283	3.0e-49	188	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650067933	271	33.7	1	271	7	282	1.0e-50	193	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650067934	261	54.69	1	256	3	258	6.0e-91	327	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
650067935	378	24.3	57	376	23	297	2.0e-32	133	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
650067938	435	27.63	12	163	6	149	1.0e-17	84.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
650067940	106	41.3	5	94	19	110	9.0e-08	48.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650067942	157	26.71	12	157	1	137	1.0e-20	92.8	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
650067944	150	18.32	14	143	15	122	8.0e-03	33.3	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
650067945	188	20	1	167	3	162	7.0e-06	44	COG0406	Broad specificity phosphatase PhoE	208
650067950	225	38.67	4	222	2	224	1.0e-49	189	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650067952	415	24.68	32	410	10	386	2.0e-20	93.7	COG2814	Predicted arabinose efflux permease, MFS family	394
650067953	279	44.89	1	272	1	268	2.0e-78	286	COG3546	Mn-containing catalase (includes spore coat protein CotJC)	277
650067956	322	35.71	1	298	4	311	4.0e-65	242	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
650067958	229	27.8	19	213	3	196	4.0e-10	58.4	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
650067959	278	29.44	38	275	21	258	3.0e-30	125	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
650067960	168	27.68	7	118	1	112	7.0e-17	80.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
650067963	327	40.75	1	314	1	315	2.0e-83	303	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650067964	293	25.94	1	289	1	289	8.0e-34	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
650067969	863	27.99	11	861	7	889	3.0e-90	326	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
650067970	448	35.88	15	302	9	306	8.0e-55	208	COG3397	Predicted carbohydrate-binding protein, contains CBM5 and CBM33 domains	308
650067972	150	28.1	10	130	2	122	1.0e-11	62.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
650067975	379	36.81	1	379	1	350	1.0e-80	293	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650067976	128	36.19	1	105	43	145	3.0e-16	77.7	COG5577	Spore coat protein CotF	145
650067979	622	43.87	351	619	8	258	2.0e-54	207	COG1240	Mg-chelatase subunit ChlD	261
650067980	307	46.92	1	302	7	347	4.0e-89	321	COG1239	Mg-chelatase subunit ChlI	423
650067981	261	48.81	3	253	2	253	2.0e-86	312	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
650067982	349	28.36	15	347	2	319	7.0e-39	154	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650067983	399	40.32	11	381	1	323	3.0e-86	312	COG0523	GTPase, G3E family	323
650067984	149	26.39	4	144	2	145	4.0e-20	90.8	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
650067985	89	61.82	35	89	7	61	2.0e-16	77.2	COG0199	Ribosomal protein S14	61
650067986	363	35.28	5	363	3	303	1.0e-75	277	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
650067987	288	41.29	1	264	6	269	1.0e-43	170	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
650067988	235	42.24	1	230	2	231	5.0e-70	257	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
650067992	84	39.29	1	83	1	72	4.0e-15	73	COG0254	Ribosomal protein L31	75
650067993	337	30.49	41	333	9	313	4.0e-45	175	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
650067994	306	26.39	13	296	2	269	8.0e-33	134	COG3689	Uncharacterized membrane protein YcgQ,  UPF0703/DUF1980 family	271
650067995	108	46.08	1	99	1	101	2.0e-24	104	COG4817	DNA-binding ferritin-like protein (Dps family)	111
650067996	115	48.67	2	114	1	111	2.0e-30	123	COG4817	DNA-binding ferritin-like protein (Dps family)	111
650067997	334	24.19	1	331	117	407	1.0e-21	97.2	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650067999	426	45.05	4	312	3	310	3.0e-65	242	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
650068000	222	37.67	2	215	23	233	4.0e-45	174	COG3208	Surfactin synthase thioesterase subunit	244
650068010	2172	37.44	907	1562	1	642	6.0e-129	457	COG1020	Non-ribosomal peptide synthetase component F	642
650068011	127	65.08	2	127	1	126	9.0e-46	175	COG0853	Aspartate 1-decarboxylase	126
650068012	353	21.58	1	290	1	287	5.0e-20	92.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650068013	317	34.75	1	304	1	290	5.0e-58	218	COG1131	ABC-type multidrug transport system, ATPase component	293
650068014	277	21.6	30	277	35	284	9.0e-06	44.5	COG0842	ABC-type multidrug transport system, permease component	286
650068015	201	25.73	1	200	63	261	5.0e-22	97.9	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
650068017	326	50.49	5	312	4	266	3.0e-96	345	COG4608	ABC-type oligopeptide transport system, ATPase component	309
650068018	331	54.4	5	320	1	315	5.0e-123	434	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650068019	272	47.74	9	272	21	286	9.0e-70	257	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650068020	314	44.3	1	314	2	317	4.0e-81	295	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650068021	244	29.25	1	244	2	291	1.0e-40	160	COG1234	Ribonuclease BN, tRNA processing enzyme	292
650068022	285	29.39	1	274	2	279	4.0e-42	165	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
650068023	249	27.35	1	227	3	226	8.0e-23	100	COG1011	FMN phosphatase YigB, HAD superfamily	229
650068024	406	18.11	1	388	4	388	5.0e-06	46	COG2814	Predicted arabinose efflux permease, MFS family	394
650068025	248	42.06	1	248	3	248	5.0e-71	260	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
650068026	269	43.07	3	264	1	267	6.0e-83	300	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650068027	295	42.91	1	273	12	286	2.0e-66	246	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650068028	310	38.75	1	309	1	316	3.0e-71	262	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650068029	432	45.79	1	428	1	426	0.0e+00	536	COG4408	Uncharacterized protein	431
650068031	293	20.82	5	275	1	272	5.0e-31	128	COG0253	Diaminopimelate epimerase	272
650068032	410	18.54	13	394	10	387	9.0e-06	45.2	COG2814	Predicted arabinose efflux permease, MFS family	394
650068033	255	42.13	1	251	2	249	1.0e-72	266	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
650068034	270	45.11	3	263	1	266	3.0e-84	305	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650068035	293	44.16	1	272	13	286	2.0e-68	252	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650068036	309	40.94	1	309	1	317	2.0e-76	279	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650068037	538	26.85	9	538	7	555	9.0e-76	277	COG0747	ABC-type transport system, periplasmic component	556
650068039	195	27.27	7	193	13	193	9.0e-11	60.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068040	292	25.44	17	291	9	282	9.0e-18	84.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650068043	284	39.52	1	281	4	293	4.0e-62	231	COG1131	ABC-type multidrug transport system, ATPase component	293
650068044	210	21.46	1	205	1	201	8.0e-11	60.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068045	414	33.88	1	414	1	419	3.0e-46	179	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
650068047	474	29.74	72	463	80	489	1.0e-57	217	COG0168	Trk-type K+ transport system, membrane component	499
650068051	108	37.8	1	81	9	90	6.0e-11	59.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650068052	431	42.92	5	427	4	424	3.0e-93	336	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
650068053	139	34.29	2	134	1	138	8.0e-35	139	COG0394	Protein-tyrosine-phosphatase	139
650068054	448	19.34	19	447	16	459	2.0e-37	150	COG0277	FAD/FMN-containing dehydrogenase	459
650068057	448	37.28	30	291	21	296	3.0e-50	192	COG3397	Predicted carbohydrate-binding protein, contains CBM5 and CBM33 domains	308
650068058	211	28.49	4	182	5	190	2.0e-25	108	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
650068060	117	27.03	12	117	3	109	4.0e-08	50.2	COG1695	DNA-binding transcriptional regulator, PadR family	138
650068062	249	19.91	28	246	44	258	1.0e-08	54	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
650068063	253	45.24	5	252	4	255	9.0e-66	243	COG1131	ABC-type multidrug transport system, ATPase component	293
650068064	114	41.44	4	111	2	111	2.0e-21	94.6	COG4817	DNA-binding ferritin-like protein (Dps family)	111
650068065	110	40	6	108	4	108	9.0e-18	82.2	COG1695	DNA-binding transcriptional regulator, PadR family	138
650068067	113	53	14	113	9	107	3.0e-30	123	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650068068	229	31.46	1	89	9	97	4.0e-09	55.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650068069	206	22.58	13	195	9	172	9.0e-19	86.9	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
650068070	309	34.22	1	300	1	297	1.0e-44	173	COG0583	DNA-binding transcriptional regulator, LysR family	297
650068071	339	28.61	3	313	17	349	5.0e-45	175	COG2021	Homoserine acetyltransferase	368
650068073	231	46.26	6	230	3	226	7.0e-67	246	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650068075	435	19.78	1	435	2	432	2.0e-28	120	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650068076	385	18.96	10	385	6	368	7.0e-14	72.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650068077	292	33	1	291	3	281	5.0e-46	178	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650068078	288	33.67	1	287	1	294	5.0e-46	178	COG1175	ABC-type sugar transport system, permease component	295
650068080	575	33.68	1	566	1	573	5.0e-122	431	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
650068081	598	36.63	19	593	2	558	1.0e-130	460	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
650068082	337	23.32	1	337	5	345	2.0e-41	163	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
650068083	455	35.82	4	447	3	456	8.0e-105	374	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
650068088	303	27.36	14	303	33	299	1.0e-24	107	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
650068089	181	20.78	1	154	3	156	2.0e-09	55.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068090	267	46.07	1	266	3	268	3.0e-61	228	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
650068091	127	25.83	8	126	15	124	1.0e-06	45.7	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
650068092	92	33.71	4	92	14	96	1.0e-05	41.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650068093	869	23.46	1	863	1	740	2.0e-121	430	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
650068095	159	23.78	4	159	3	157	2.0e-04	38.8	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
650068096	320	21.74	1	316	4	303	1.0e-18	87	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650068100	214	39.23	1	209	4	211	2.0e-49	189	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
650068101	369	44.9	9	367	2	353	2.0e-90	326	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
650068102	287	39.79	7	285	5	288	3.0e-68	252	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650068105	355	34.81	2	355	1	356	1.0e-72	267	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
650068106	473	18.32	10	452	3	457	6.0e-38	152	COG0277	FAD/FMN-containing dehydrogenase	459
650068109	212	26.07	7	211	2	204	3.0e-29	121	COG0778	Nitroreductase	207
650068110	119	31.97	1	119	1	120	9.0e-13	65.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
650068111	320	43.58	1	317	1	332	6.0e-67	247	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
650068112	266	31.27	5	263	1	248	6.0e-26	111	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
650068113	282	38.56	1	235	2	235	8.0e-53	200	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
650068114	269	44.25	1	224	3	228	1.0e-65	243	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
650068115	275	35.48	1	241	4	248	2.0e-41	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650068118	383	41.77	1	380	1	390	2.0e-81	296	COG0183	Acetyl-CoA acetyltransferase	392
650068119	497	31.14	1	494	11	527	5.0e-88	318	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650068120	184	48.35	1	182	5	184	8.0e-30	123	COG1268	Biotin transporter BioY	184
650068121	319	16.8	40	277	30	233	5.0e-10	58.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650068123	179	31.1	1	163	3	162	2.0e-24	105	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650068124	134	25.23	21	124	15	121	2.0e-04	38	COG3631	Ketosteroid isomerase-related protein	133
650068126	300	31.29	1	291	1	292	4.0e-42	165	COG0583	DNA-binding transcriptional regulator, LysR family	297
650068127	168	35	32	130	9	104	7.0e-07	47.3	COG4270	Uncharacterized membrane protein	131
650068128	383	19.8	80	375	2	282	7.0e-17	82.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650068129	223	37.02	3	202	68	270	3.0e-39	155	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
650068132	454	30.92	1	446	4	458	2.0e-94	340	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650068133	269	41.77	28	269	7	254	7.0e-62	230	COG2602	Beta-lactamase class D	254
650068135	161	28.95	1	152	1	136	3.0e-30	124	COG1959	DNA-binding transcriptional regulator, IscR family	150
650068138	231	31.77	3	190	2	192	4.0e-31	128	COG0300	Short-chain dehydrogenase	265
650068140	300	33.44	1	295	2	293	6.0e-60	224	COG1131	ABC-type multidrug transport system, ATPase component	293
650068141	308	31.27	1	300	2	293	2.0e-56	212	COG1131	ABC-type multidrug transport system, ATPase component	293
650068142	214	22	15	214	7	196	2.0e-11	62.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068146	292	24.22	7	290	3	280	5.0e-26	112	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650068148	304	34.31	1	302	1	293	3.0e-64	238	COG1131	ABC-type multidrug transport system, ATPase component	293
650068149	312	28.48	2	309	39	329	6.0e-32	131	COG0642	Signal transduction histidine kinase	336
650068150	232	40.43	3	230	1	225	1.0e-61	229	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650068152	408	22.94	6	392	15	404	7.0e-20	92.2	COG0738	Fucose permease	422
650068155	375	17.86	9	366	18	381	2.0e-16	80.2	COG2814	Predicted arabinose efflux permease, MFS family	394
650068157	288	33.57	1	277	2	287	3.0e-57	215	COG1131	ABC-type multidrug transport system, ATPase component	293
650068158	98	39.58	1	96	29	124	2.0e-15	74.1	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
650068159	335	36.18	1	332	1	326	8.0e-69	254	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650068160	108	35.71	18	101	18	100	8.0e-07	45.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650068161	303	33.12	1	302	5	310	2.0e-45	175	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650068162	135	31.4	7	127	4	121	3.0e-19	87.6	COG3682	Predicted transcriptional regulator	123
650068163	637	25.64	7	388	3	337	2.0e-35	144	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
650068164	136	33.33	7	126	4	120	4.0e-19	86.8	COG3682	Predicted transcriptional regulator	123
650068166	267	22.54	4	265	13	276	2.0e-27	116	COG1562	Phytoene/squalene synthetase	288
650068168	187	15.98	1	169	1	167	2.0e-05	42.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068170	235	23.64	23	232	15	230	1.0e-21	96.9	COG1018	Ferredoxin-NADP reductase	266
650068171	751	46.21	130	751	262	930	0.0e+00	790	COG0178	Excinuclease UvrABC ATPase subunit	935
650068172	132	23.08	1	131	6	148	2.0e-13	68.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
650068173	109	37.8	1	82	9	90	2.0e-08	51.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650068176	276	39.15	2	275	1	281	4.0e-61	228	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650068177	294	37.76	7	291	5	290	5.0e-55	208	COG1175	ABC-type sugar transport system, permease component	295
650068178	432	20.19	26	432	19	431	1.0e-27	117	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650068182	183	30.73	1	178	2	179	5.0e-26	110	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650068183	279	22.74	30	277	53	311	2.0e-29	122	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
650068186	487	27.24	194	486	27	325	2.0e-31	130	COG3469	Chitinase	332
650068190	288	36.07	12	287	8	281	4.0e-48	185	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650068191	290	36.21	1	286	13	301	2.0e-58	219	COG4209	ABC-type polysaccharide transport system, permease component	309
650068192	473	21.1	5	468	2	428	8.0e-21	95.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650068193	334	36.9	2	331	1	330	1.0e-64	240	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650068195	206	22.67	12	183	10	179	1.0e-08	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068196	454	31.17	6	451	12	453	3.0e-58	219	COG0534	Na+-driven multidrug efflux pump	455
650068198	267	32.32	5	267	1	260	7.0e-33	134	COG3694	ABC-type uncharacterized transport system, permease component	260
650068199	264	30.42	2	264	8	268	1.0e-31	130	COG4587	ABC-type uncharacterized transport system, permease component	268
650068200	327	44.55	4	324	4	324	6.0e-93	334	COG4586	ABC-type uncharacterized transport system, ATPase component	325
650068201	391	22.38	53	383	18	317	5.0e-20	92.4	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
650068207	694	23.68	259	676	10	407	4.0e-34	140	COG0840	Methyl-accepting chemotaxis protein	408
650068208	422	22.45	28	320	92	350	1.0e-21	97.8	COG2273	Beta-glucanase, GH16 family	355
650068211	175	52.66	1	168	6	174	2.0e-61	228	COG0225	Peptide methionine sulfoxide reductase MsrA	174
650068212	455	31.83	130	439	35	330	3.0e-40	159	COG0642	Signal transduction histidine kinase	336
650068213	225	42.57	5	201	1	201	2.0e-49	189	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650068216	189	20.11	11	175	15	195	2.0e-06	46.1	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
650068217	89	40.45	1	89	1	88	1.0e-16	77.9	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
650068218	244	54.73	1	243	1	243	2.0e-88	318	COG4821	Uncharacterized protein, contains SIS (Sugar ISomerase) phosphosugar binding domain	243
650068219	242	39.43	1	237	2	243	6.0e-52	197	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
650068220	330	38.39	1	330	1	316	1.0e-98	353	COG1735	Predicted metal-dependent hydrolase, phosphotriesterase family	316
650068221	431	39.78	1	431	5	448	2.0e-107	382	COG3037	Ascorbate-specific PTS system EIIC-type component UlaA	481
650068222	87	42.22	1	87	2	91	4.0e-17	79.5	COG3414	Phosphotransferase system, galactitol-specific IIB component	93
650068223	147	32.19	1	142	3	146	8.0e-23	99.7	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
650068224	235	42.36	7	233	3	229	2.0e-62	232	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650068225	482	27.71	134	482	2	330	4.0e-38	152	COG0642	Signal transduction histidine kinase	336
650068226	254	48.64	8	225	1	220	3.0e-69	255	COG1136	ABC-type lipoprotein export system, ATPase component	226
650068231	200	26.4	6	179	5	182	8.0e-25	107	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650068232	69	50	3	64	12	73	4.0e-13	66.5	COG4224	Uncharacterized protein YnzC, UPF0291/DUF896 family	77
650068233	498	28.62	1	492	1	509	4.0e-86	312	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650068236	369	40.5	2	359	1	357	2.0e-83	302	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
650068237	273	23.49	138	268	10	158	5.0e-09	55	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650068238	490	25.9	45	436	51	440	3.0e-38	153	COG3119	Arylsulfatase A or related enzyme	475
650068239	305	38.94	2	304	1	303	6.0e-69	254	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
650068241	295	34.65	193	293	19	119	3.0e-20	93	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650068244	255	46.27	3	252	1	250	3.0e-44	172	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650068245	623	22.12	91	610	19	455	1.0e-35	145	COG2972	Sensor histidine kinase YesM	456
650068248	526	22.02	1	383	1	349	4.0e-22	99.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650068249	290	34.83	6	289	5	281	2.0e-48	186	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650068250	319	47.68	18	319	8	309	1.0e-91	330	COG4209	ABC-type polysaccharide transport system, permease component	309
650068251	60	30.91	1	54	1	55	3.0e-05	39.9	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
650068253	765	61.03	428	758	1	329	2.0e-124	440	COG0620	Methionine synthase II (cobalamin-independent)	330
650068255	230	44.05	4	228	3	228	3.0e-60	225	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650068256	281	20.69	1	276	3	274	2.0e-21	96.4	COG1082	Sugar phosphate isomerase/epimerase	274
650068257	357	27.37	5	352	1	342	4.0e-50	192	COG0673	Predicted dehydrogenase	342
650068258	339	56.53	11	339	11	336	2.0e-89	323	COG4211	ABC-type glucose/galactose transport system, permease component	336
650068259	332	27.8	46	318	36	312	3.0e-27	116	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650068260	544	27.29	1	539	1	471	6.0e-63	235	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650068261	438	28.74	2	431	22	453	5.0e-51	195	COG0534	Na+-driven multidrug efflux pump	455
650068262	386	66.67	5	384	13	393	0.0e+00	574	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
650068263	297	38.14	6	292	4	290	6.0e-65	240	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650068268	173	35.16	1	171	3	184	2.0e-27	115	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650068269	760	32.78	27	370	48	388	9.0e-61	228	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
650068270	423	42.86	310	414	22	126	2.0e-23	104	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650068271	390	31.39	74	374	1	306	8.0e-47	181	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
650068273	397	23	8	392	13	419	9.0e-25	107	COG0738	Fucose permease	422
650068276	543	21.09	1	530	1	636	6.0e-39	155	COG0210	Superfamily I DNA or RNA helicase	655
650068277	599	23.68	1	436	1	458	3.0e-34	140	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
650068286	239	51.46	4	239	6	241	3.0e-79	288	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
650068287	402	21.9	55	397	61	393	2.0e-07	50.6	COG2814	Predicted arabinose efflux permease, MFS family	394
650068288	574	42.37	15	570	7	510	0.0e+00	553	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
650068289	610	51.51	14	610	1	587	0.0e+00	663	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
650068291	218	33.03	5	218	13	226	2.0e-38	152	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
650068293	163	45.64	1	147	5	150	7.0e-39	153	COG1683	Uncharacterized conserved protein YbbK, DUF523 family	156
650068294	265	40	9	113	22	126	8.0e-19	87.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650068295	362	31.94	2	356	1	340	2.0e-51	196	COG0673	Predicted dehydrogenase	342
650068296	316	34.17	192	311	2	120	1.0e-17	84.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650068297	332	27.86	1	329	3	342	8.0e-42	164	COG0673	Predicted dehydrogenase	342
650068301	248	33	8	107	3	102	7.0e-15	74.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
650068302	308	29.61	3	305	1	280	3.0e-46	179	COG5504	Uncharacterized protein YjaZ	280
650068305	213	32.23	1	205	2	212	5.0e-46	177	COG1131	ABC-type multidrug transport system, ATPase component	293
650068307	246	30.33	3	246	5	229	3.0e-16	78.9	COG2801	Transposase InsO and inactivated derivatives	232
650068308	107	23.71	9	102	6	102	1.0e-04	38.7	COG2963	Transposase and inactivated derivatives	116
650068314	381	28.29	33	379	1	333	8.0e-45	174	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650068317	980	30.58	14	977	49	943	0.0e+00	488	COG0383	Alpha-mannosidase	943
650068318	308	47	9	308	10	309	2.0e-89	322	COG4209	ABC-type polysaccharide transport system, permease component	309
650068319	298	29.7	1	297	3	281	2.0e-44	173	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650068320	552	18.51	5	413	1	374	3.0e-13	70.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650068325	124	31.48	8	113	3	110	2.0e-10	58.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650068326	160	27.56	3	152	5	147	2.0e-12	65.5	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
650068327	180	17.61	8	180	12	184	2.0e-08	52.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650068330	316	36.82	19	314	1	292	2.0e-55	209	COG1175	ABC-type sugar transport system, permease component	295
650068331	289	36.79	12	288	3	281	1.0e-52	200	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650068332	459	22.37	1	454	2	429	2.0e-20	94.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650068333	618	28.84	93	614	1	514	5.0e-60	226	COG1657	Squalene cyclase	517
650068338	481	21.87	17	375	4	321	4.0e-27	116	COG2312	Erythromycin esterase homolog	405
650068342	197	22.73	1	175	4	179	9.0e-07	47	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068344	280	31	1	270	1	297	2.0e-35	143	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650068345	271	24.32	34	138	10	120	1.0e-03	37.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
650068347	278	37.77	7	277	6	281	2.0e-47	183	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650068348	302	36.82	1	292	2	290	5.0e-42	165	COG1175	ABC-type sugar transport system, permease component	295
650068360	299	24.1	1	298	1	307	3.0e-41	162	COG0657	Acetyl esterase/lipase	312
650068363	319	36.36	198	318	2	122	3.0e-20	92.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650068372	286	29.79	1	284	1	290	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
650068374	129	42.52	1	126	3	126	8.0e-27	112	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650068377	203	49.74	11	203	7	188	2.0e-48	185	COG3644	Uncharacterized protein	194
650068379	297	25.33	1	295	2	281	1.0e-19	90.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650068380	198	21.61	1	198	2	198	5.0e-10	58.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068381	306	27.02	55	297	31	271	7.0e-30	124	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
650068382	314	16.78	9	296	6	278	2.0e-06	46.6	COG3595	Uncharacterized conserved protein YvlB, contains  DUF4097 and DUF4098 domains	318
650068389	219	17.91	1	201	1	197	3.0e-09	55.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068391	231	39.47	1	223	1	227	8.0e-53	200	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650068392	382	33.44	70	374	26	327	9.0e-44	171	COG0642	Signal transduction histidine kinase	336
650068394	120	31.09	4	118	18	130	2.0e-10	58	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650068395	505	31.73	1	344	1	350	3.0e-53	203	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
650068396	161	24.47	47	140	17	110	3.0e-07	48.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
650068401	181	22.67	1	150	3	151	1.0e-08	53.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068405	205	21.47	21	203	4	194	1.0e-09	57	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068406	308	24.92	1	300	1	292	2.0e-25	110	COG1893	Ketopantoate reductase	307
650068408	269	31.75	20	269	1	231	1.0e-19	90.8	COG2801	Transposase InsO and inactivated derivatives	232
650068411	332	25.16	26	327	20	330	1.0e-34	140	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650068412	160	28.57	1	154	1	150	1.0e-21	96.2	COG1959	DNA-binding transcriptional regulator, IscR family	150
650068413	216	39.11	4	205	1	200	5.0e-49	187	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650068414	1015	34.3	284	626	1	336	4.0e-45	177	COG0642	Signal transduction histidine kinase	336
650068418	399	34.17	11	397	25	411	4.0e-76	278	COG2124	Cytochrome P450	411
650068423	416	22.92	10	357	1	344	9.0e-19	88.3	COG2814	Predicted arabinose efflux permease, MFS family	394
650068426	214	69	1	100	1	100	7.0e-42	163	COG0831	Urease gamma subunit	100
650068427	570	71.23	1	569	1	567	0.0e+00	952	COG0804	Urease alpha subunit	568
650068429	603	30	21	213	30	219	2.0e-28	121	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
650068430	440	21.7	203	414	1	211	2.0e-19	91	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650068433	821	27.06	412	660	3	253	3.0e-36	147	COG1216	Glycosyltransferase, GT2 family	305
650068436	317	16.2	61	317	97	379	3.0e-13	69.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650068438	175	36.26	1	175	3	184	1.0e-27	116	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650068439	300	36.1	6	281	16	274	1.0e-38	153	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
650068440	312	39.07	1	279	5	273	2.0e-43	169	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
650068442	312	35.37	1	309	5	303	6.0e-56	211	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
650068448	130	24.58	12	123	16	121	4.0e-03	33.7	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
650068449	109	29.57	1	108	10	123	2.0e-11	60.7	COG0073	tRNA-binding EMAP/Myf domain	123
650068454	310	47.08	11	310	2	309	1.0e-91	329	COG0039	Malate/lactate dehydrogenase	313
650068455	195	28.5	3	193	6	205	2.0e-18	85.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
650068456	184	24.27	7	108	1	103	1.0e-07	49.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
650068457	243	40.61	4	230	23	251	5.0e-46	177	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650068458	258	44.98	10	258	4	243	2.0e-83	302	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650068459	338	25.62	9	319	2	318	2.0e-25	109	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650068462	387	34.55	1	380	11	390	3.0e-57	216	COG2814	Predicted arabinose efflux permease, MFS family	394
650068463	137	32.8	10	132	9	126	2.0e-11	61.5	COG3607	Predicted lactoylglutathione lyase	133
650068464	419	37.09	18	410	4	393	2.0e-89	323	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650068465	610	25.47	71	479	36	433	7.0e-58	219	COG5520	O-Glycosyl hydrolase	433
650068466	211	29.63	4	191	2	180	5.0e-23	100	COG0655	Multimeric flavodoxin WrbA	207
650068467	216	33.95	2	215	4	217	6.0e-44	170	COG4845	Chloramphenicol O-acetyltransferase	219
650068469	206	29.38	1	190	2	191	2.0e-29	122	COG0406	Broad specificity phosphatase PhoE	208
650068473	184	33.33	5	174	17	180	2.0e-29	122	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
650068474	244	23.24	36	216	43	226	4.0e-16	78.8	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
650068476	504	28.86	26	362	52	390	7.0e-46	178	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650068478	367	27.46	25	298	11	289	7.0e-50	191	COG2008	Threonine aldolase	342
650068479	307	46.62	1	296	2	292	5.0e-78	284	COG1230	Co/Zn/Cd efflux system component	296
650068481	593	28.05	24	591	23	561	3.0e-85	309	COG4533	DNA-binding transcriptional regulator SgrR  of sgrS sRNA, contains a MarR-type HTH domain and a periplasmic-type solute-binding domain	564
650068483	374	18.9	14	356	16	372	2.0e-04	40.6	COG0814	Amino acid permease	415
650068486	426	31.8	2	425	5	427	3.0e-76	279	COG0124	Histidyl-tRNA synthetase	429
650068487	688	57.83	18	515	1	489	0.0e+00	706	COG0753	Catalase	496
650068488	305	20.48	1	293	7	292	2.0e-03	36.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
650068489	129	46.51	1	129	2	129	1.0e-35	141	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
650068493	364	44.41	2	364	94	448	3.0e-124	438	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
650068498	261	32.16	8	259	4	258	9.0e-46	177	COG2162	Arylamine N-acetyltransferase	275
650068499	159	39.52	1	123	3	125	2.0e-35	142	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
650068502	420	46.17	1	418	147	562	3.0e-113	402	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650068504	218	41.83	7	214	2	209	8.0e-53	200	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650068506	186	23.57	41	180	2	157	7.0e-16	77.2	COG1225	Peroxiredoxin	157
650068507	470	39.69	25	467	2	442	2.0e-99	356	COG3182	Uncharacterized iron-regulated membrane protein	442
650068509	243	36.4	6	227	5	232	5.0e-56	210	COG1131	ABC-type multidrug transport system, ATPase component	293
650068510	273	20.44	8	269	7	274	7.0e-09	54.7	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
650068511	191	20.11	14	170	3	176	7.0e-04	37.7	COG4314	Nitrous oxide reductase accessory protein NosL	176
650068512	459	27.39	52	421	30	400	2.0e-42	167	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
650068514	620	24.19	1	614	1	561	3.0e-74	273	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650068515	574	31.5	7	571	11	567	2.0e-93	337	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650068520	727	23.01	9	726	7	749	8.0e-74	272	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
650068521	207	20.73	10	201	1	192	1.0e-07	50	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068522	211	31.13	8	211	4	207	3.0e-30	125	COG0778	Nitroreductase	207
650068523	152	25.37	21	152	5	135	3.0e-15	74.6	COG1959	DNA-binding transcriptional regulator, IscR family	150
650068524	667	38.35	1	401	6	403	5.0e-73	269	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
650068525	237	41.67	1	235	17	251	2.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650068526	202	15.73	3	180	1	178	8.0e-10	57.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068527	251	42.46	3	248	2	250	5.0e-53	201	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650068530	278	35	150	269	1	120	3.0e-22	99.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650068533	443	24.31	10	257	12	258	7.0e-25	108	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
650068536	335	28.11	96	330	1	248	5.0e-26	112	COG2365	Protein tyrosine/serine phosphatase	249
650068537	279	31.95	8	269	13	276	1.0e-41	163	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650068538	263	37.08	1	263	16	282	5.0e-47	181	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650068539	208	55.9	1	195	1	195	5.0e-74	270	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
650068540	307	36.75	9	302	2	299	6.0e-53	201	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
650068541	217	30.52	1	213	12	220	3.0e-21	95.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
650068542	217	31.94	3	213	3	218	2.0e-31	129	COG1451	Predicted metal-dependent hydrolase	223
650068544	271	43.49	9	271	5	265	2.0e-44	172	COG0428	Zinc transporter ZupT	266
650068546	484	42.11	8	480	2	472	0.0e+00	463	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650068549	326	35.58	3	323	4	308	3.0e-60	225	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650068551	211	22.89	3	203	7	206	9.0e-25	106	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650068552	412	21.29	8	363	1	344	2.0e-34	140	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
650068553	187	25.62	16	170	48	207	5.0e-09	54.5	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650068555	215	37.96	1	212	1	216	9.0e-49	186	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
650068556	130	29.73	57	130	1	68	6.0e-09	53.5	COG3478	Predicted nucleic-acid-binding protein, contains Zn-ribbon domain	68
650068558	223	30	4	222	13	227	6.0e-26	111	COG1011	FMN phosphatase YigB, HAD superfamily	229
650068560	194	23.84	19	189	8	170	2.0e-14	72.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650068562	180	38.41	17	179	18	180	4.0e-25	107	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
650068564	177	28.39	23	174	26	180	1.0e-20	93.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650068566	388	17.46	133	373	23	258	6.0e-05	42.3	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
650068567	133	29.55	1	131	5	132	3.0e-14	71.1	COG5341	Uncharacterized protein	132
650068573	201	34.93	2	201	1	209	3.0e-44	171	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650068574	373	27.79	6	364	1	365	9.0e-45	174	COG4585	Signal transduction histidine kinase	365
650068575	377	26.2	5	368	10	378	5.0e-53	202	COG2311	Uncharacterized membrane protein YeiB	394
650068576	484	30.09	4	478	7	571	1.0e-86	314	COG1966	Carbon starvation protein CstA	575
650068577	245	39.92	5	245	2	243	5.0e-46	177	COG3279	DNA-binding response regulator, LytR/AlgR family	244
650068578	583	39.9	1	574	1	550	0.0e+00	503	COG3275	Sensor histidine kinase, LytS/YehU family	557
650068583	200	16.58	1	196	3	201	7.0e-13	67.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650068584	467	27.6	1	440	1	411	1.0e-61	231	COG2124	Cytochrome P450	411
650068591	185	31.32	9	185	4	185	2.0e-25	108	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650068593	237	54.46	14	237	13	236	2.0e-74	272	COG3826	Uncharacterized protein	236
650068594	181	44.74	22	170	17	168	1.0e-41	162	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
650068595	200	40.11	1	182	1	180	3.0e-53	201	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
650068601	247	21.8	9	238	26	272	3.0e-11	62.7	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
650068603	125	37.38	5	111	2	106	2.0e-19	87.8	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650068607	321	41.19	2	311	1	316	3.0e-70	258	COG3940	Beta-xylosidase, GH43 family	324
650068610	279	36.3	1	278	3	281	3.0e-55	208	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650068611	326	37.46	38	326	5	294	2.0e-63	235	COG1175	ABC-type sugar transport system, permease component	295
650068612	455	23.82	44	452	23	432	9.0e-34	138	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650068613	307	40.52	2	306	3	306	3.0e-80	291	COG4189	Predicted transcriptional regulator	308
650068616	264	32.71	3	260	1	251	1.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650068617	281	53.52	5	281	1	280	2.0e-103	369	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
650068618	401	44.59	5	391	8	391	2.0e-73	269	COG2814	Predicted arabinose efflux permease, MFS family	394
650068619	132	40.52	1	116	4	119	5.0e-31	126	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650068620	331	24.68	31	327	11	318	8.0e-33	134	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650068621	571	43.61	1	571	3	567	0.0e+00	504	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650068622	344	42.47	14	344	1	331	9.0e-62	230	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
650068623	351	43.77	28	350	6	332	7.0e-58	217	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
650068624	299	37.77	30	299	5	281	2.0e-50	192	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650068625	296	35.27	6	296	3	294	4.0e-56	211	COG1175	ABC-type sugar transport system, permease component	295
650068626	452	32.62	47	450	24	433	2.0e-48	186	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650068627	443	29.02	21	409	19	425	2.0e-49	190	COG0038	H+/Cl- antiporter ClcA	443
650068629	295	29.62	5	279	4	290	2.0e-47	182	COG1131	ABC-type multidrug transport system, ATPase component	293
650068630	122	30.33	1	122	2	122	2.0e-22	97.6	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
650068632	674	21.43	17	251	29	227	5.0e-06	46.8	COG2339	Membrane proteinase PrsW, cleaves anti-sigma factor RsiW, M82 family	274
650068634	216	44.12	3	206	2	201	3.0e-56	211	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
650068635	251	57.37	1	251	1	251	1.0e-93	336	COG1540	Lactam utilization protein B (function unknown)	252
650068636	356	44.97	3	320	1	304	1.0e-95	343	COG1984	Allophanate hydrolase subunit 2	314
650068637	241	45.89	9	236	3	221	2.0e-66	245	COG2049	Allophanate hydrolase subunit 1	223
650068640	167	20.77	1	164	2	184	4.0e-06	44.5	COG1011	FMN phosphatase YigB, HAD superfamily	229
650068641	243	24.61	1	189	1	152	4.0e-09	55.4	COG0622	Predicted phosphodiesterase	172
650068642	206	32.61	18	199	3	182	2.0e-29	122	COG1713	HD superfamily phosphohydrolase YqeK (fused to NMNAT in mycoplasms)	187
650068644	319	36.86	25	315	1	290	2.0e-56	213	COG1175	ABC-type sugar transport system, permease component	295
650068645	273	39.86	2	272	7	281	8.0e-51	193	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650068646	526	18.95	49	428	52	372	3.0e-13	70.6	COG2814	Predicted arabinose efflux permease, MFS family	394
650068648	409	43.7	7	408	3	384	3.0e-94	338	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
650068651	190	37.36	1	181	1	176	2.0e-36	145	COG3797	Uncharacterized conserved protein, DUF1697 family	178
650068652	463	32.6	2	456	6	444	8.0e-78	284	COG1232	Protoporphyrinogen oxidase	444
650068653	247	47.53	6	225	5	227	2.0e-63	236	COG2357	ppGpp synthetase catalytic domain (RelA/SpoT-type nucleotidyltranferase)	231
650068654	105	34.09	1	87	9	96	7.0e-09	52.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650068656	224	26.78	1	215	7	245	1.0e-25	109	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650068657	558	21.93	255	518	2	235	6.0e-29	122	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
650068658	5441	30.41	3439	4500	1	1031	0.0e+00	738	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
650068659	1939	31.23	1024	1888	1	855	0.0e+00	570	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
650068663	192	20.2	1	192	3	175	2.0e-12	65.7	COG0250	Transcription antitermination factor NusG	178
650068664	582	26.26	15	212	1	171	2.0e-21	98.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650068666	456	26.63	29	423	4	336	3.0e-51	196	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650068667	269	47.64	15	268	5	258	1.0e-56	213	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650068668	286	50.39	26	281	3	258	1.0e-61	230	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650068669	339	30.35	1	339	1	330	1.0e-42	167	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650068670	258	52.21	6	251	4	248	2.0e-85	308	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650068671	190	47.12	1	188	3	193	7.0e-65	240	COG1435	Thymidine kinase	201
650068673	288	44.65	14	280	13	283	2.0e-56	212	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
650068676	216	29.03	15	200	33	218	2.0e-27	115	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
650068680	137	46.02	3	115	1	113	7.0e-25	106	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
650068681	97	46.59	1	88	2	89	1.0e-10	57.8	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
650068682	159	45.57	1	158	1	158	3.0e-38	151	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
650068683	494	33.86	1	492	1	499	1.0e-67	251	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
650068684	112	46.09	1	112	1	115	1.0e-24	104	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
650068685	952	39.38	4	646	1	606	2.0e-128	453	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
650068687	208	28.8	11	200	18	208	5.0e-25	107	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650068690	336	22.18	82	334	46	258	2.0e-13	70.5	COG4278	Uncharacterized protein	269
650068694	114	37.86	11	108	1	103	2.0e-09	54.5	COG1695	DNA-binding transcriptional regulator, PadR family	138
650068695	345	45.51	1	324	3	333	1.0e-96	346	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650068696	144	26.36	18	127	1	106	2.0e-04	38.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
650068697	197	28.35	1	190	71	264	5.0e-27	114	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
650068698	280	52.35	7	278	2	278	3.0e-90	325	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
650068699	338	33.55	46	337	17	317	7.0e-46	178	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
650068700	321	20.34	13	300	2	268	1.0e-26	114	COG3689	Uncharacterized membrane protein YcgQ,  UPF0703/DUF1980 family	271
650068701	350	30.1	4	306	1	274	3.0e-42	166	COG0523	GTPase, G3E family	323
650068703	403	39.26	6	376	1	323	6.0e-87	314	COG0523	GTPase, G3E family	323
650068704	135	53.27	8	114	3	108	7.0e-32	129	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650068705	187	26.94	10	186	10	202	2.0e-34	138	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
650068706	210	45.02	1	209	4	214	1.0e-53	203	COG0269	3-keto-L-gulonate-6-phosphate decarboxylase	217
650068707	322	48.71	14	322	13	313	1.0e-55	210	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650068708	326	31.21	35	313	33	314	1.0e-41	163	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650068709	539	26.78	1	531	1	473	2.0e-63	237	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650068710	180	34.25	1	179	1	178	2.0e-31	128	COG0431	NAD(P)H-dependent FMN reductase	184
650068712	186	29.78	1	175	1	176	3.0e-25	108	COG0431	NAD(P)H-dependent FMN reductase	184
650068713	222	48.87	2	222	1	209	1.0e-57	216	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650068717	496	31.84	7	488	4	473	2.0e-80	293	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650068718	592	29.47	20	589	14	566	2.0e-77	283	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650068722	103	55.24	1	103	1	105	1.0e-24	104	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
650068723	142	59.57	1	141	1	141	3.0e-45	174	COG4154	L-fucose mutarotase/ribose pyranase, RbsD/FucU family	144
650068724	505	23.62	5	503	1	495	2.0e-68	253	COG1070	Sugar (pentulose or hexulose) kinase	502
650068725	219	33.49	1	210	3	216	1.0e-38	153	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650068726	597	37.74	15	595	1	470	1.0e-105	377	COG2407	L-fucose isomerase or related protein	470
650068727	285	39	182	281	24	123	8.0e-24	104	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650068728	128	35.23	39	126	12	99	3.0e-11	60.8	COG0633	Ferredoxin	102
650068732	317	40.69	5	316	1	305	2.0e-62	232	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
650068733	228	42.33	1	213	2	214	9.0e-55	206	COG3142	Copper homeostasis protein CutC	241
650068734	486	37.18	52	483	70	484	9.0e-99	354	COG0260	Leucyl aminopeptidase	485
650068735	329	52.58	4	313	2	266	2.0e-106	379	COG4608	ABC-type oligopeptide transport system, ATPase component	309
650068736	334	59.25	5	322	1	314	0.0e+00	466	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650068737	301	51.81	27	300	12	287	2.0e-75	275	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650068738	308	49.37	1	306	1	316	3.0e-89	321	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650068741	334	32.21	6	329	13	337	8.0e-59	221	COG4448	L-asparaginase II	339
650068742	386	27.6	83	386	8	313	8.0e-44	171	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
650068745	215	40.48	1	208	4	213	4.0e-44	171	COG2345	Predicted transcriptional regulator, ArsR family	218
650068746	367	30.83	1	353	7	390	6.0e-57	214	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
650068747	502	38.53	22	491	9	475	4.0e-120	425	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
650068748	243	32.56	9	218	3	213	2.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650068750	245	27.88	19	242	2	216	3.0e-23	101	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
650068751	506	46.42	6	465	2	457	0.0e+00	519	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
650068753	258	44.14	1	255	1	249	5.0e-67	247	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650068754	489	26.54	1	469	4	482	2.0e-77	283	COG1070	Sugar (pentulose or hexulose) kinase	502
650068755	421	62.68	1	418	1	418	0.0e+00	699	COG4806	L-rhamnose isomerase	419
650068756	689	50.6	2	418	1	404	0.0e+00	521	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
650068757	101	42.53	2	88	5	91	7.0e-18	82.3	COG4495	Uncharacterized protein	109
650068760	150	24.47	1	94	1	94	1.0e-07	49.2	COG4842	Uncharacterized conserved protein YukE	97
650068763	360	29.71	219	343	4	137	4.0e-18	85.7	COG1225	Peroxiredoxin	157
650068764	172	27.85	1	156	2	150	1.0e-07	49.5	COG1247	L-amino acid N-acyltransferase YncA	169
650068766	219	18.97	33	202	38	211	1.0e-13	70.3	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
650068767	315	29.49	5	296	60	341	3.0e-38	152	COG0673	Predicted dehydrogenase	342
650068769	243	50	1	243	3	239	4.0e-81	294	COG3828	Type 1 glutamine amidotransferase (GATase1)-like domain	239
650068770	386	33.42	1	385	1	342	1.0e-61	230	COG0673	Predicted dehydrogenase	342
650068771	350	39.6	8	350	4	333	1.0e-71	263	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650068772	248	28.92	1	248	7	253	4.0e-09	55.4	COG0730	Uncharacterized membrane protein YfcA	258
650068773	417	21.08	14	396	8	412	1.0e-20	94.5	COG0738	Fucose permease	422
650068774	587	20.47	11	587	7	607	2.0e-53	204	COG1874	Beta-galactosidase GanA	673
650068776	130	37.78	1	129	8	142	2.0e-11	61.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650068780	265	41.41	5	260	3	252	3.0e-63	235	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650068781	343	44.38	1	340	6	352	3.0e-103	368	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
650068782	273	25.19	1	265	2	264	1.0e-35	143	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
650068783	306	41.91	9	276	8	277	2.0e-61	229	COG4132	ABC-type uncharacterized transport system, permease component	282
650068784	374	26.25	78	369	1	296	2.0e-33	136	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
650068785	214	33.02	1	210	72	281	3.0e-29	121	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650068787	262	54.76	2	253	1	252	3.0e-89	321	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
650068788	341	22.92	1	341	1	292	6.0e-30	125	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
650068790	302	37.12	1	296	84	376	2.0e-67	249	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
650068792	281	45.49	5	281	3	256	2.0e-70	259	COG4107	ABC-type phosphonate transport system, ATPase component	258
650068793	377	40.91	3	364	2	350	6.0e-82	298	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
650068796	142	26.24	1	138	6	146	8.0e-08	49.6	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
650068797	239	31.14	5	232	10	234	5.0e-37	147	COG2188	DNA-binding transcriptional regulator, GntR family	236
650068798	211	33.97	30	182	37	190	2.0e-22	99.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
650068799	284	32.81	1	253	2	247	9.0e-32	130	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
650068801	497	41.02	1	497	2	501	0.0e+00	590	COG3534	Alpha-L-arabinofuranosidase	501
650068802	248	57.72	2	247	1	240	7.0e-98	350	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650068803	209	43.01	8	193	13	194	1.0e-43	169	COG0765	ABC-type amino acid transport system, permease component	222
650068804	255	36.3	1	255	2	270	3.0e-38	152	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650068807	309	55.95	1	309	1	310	1.0e-99	356	COG1227	Inorganic pyrophosphatase/exopolyphosphatase	311
650068808	340	26.36	13	340	4	286	2.0e-53	203	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
650068809	316	61.59	35	316	54	342	2.0e-93	336	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
650068810	442	38.58	88	423	1	323	8.0e-69	254	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
650068812	276	30.18	1	270	6	280	4.0e-54	205	COG1307	Fatty acid-binding protein DegV (function unknown)	282
650068814	251	39.33	161	249	1	85	3.0e-14	72.3	COG3860	Uncharacterized protein	89
650068817	431	19.3	44	413	41	391	2.0e-08	54.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650068820	213	31.46	4	209	1	211	1.0e-29	123	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650068823	234	20.5	69	221	56	215	3.0e-05	42.6	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
650068826	214	25.91	11	203	30	222	7.0e-22	97.3	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
650068830	239	48.33	1	207	6	212	4.0e-53	201	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
650068831	195	33.85	5	173	7	195	3.0e-30	124	COG0572	Uridine kinase	218
650068834	173	38.86	2	166	3	174	7.0e-29	120	COG3981	Predicted acetyltransferase	174
650068837	534	22.54	193	523	69	420	8.0e-35	142	COG3858	Spore germination protein YaaH	423
650068838	650	28.86	24	648	52	689	9.0e-124	437	COG1523	Pullulanase/glycogen debranching enzyme	697
650068840	367	20.61	1	356	25	358	2.0e-17	83.7	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
650068841	326	43.03	1	319	1	328	5.0e-71	261	COG0714	MoxR-like ATPase	329
650068842	132	21.88	1	94	2	97	4.0e-08	50.3	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
650068844	321	29.22	5	305	2	303	6.0e-40	158	COG0492	Thioredoxin reductase	305
650068845	411	35.39	22	197	1	178	1.0e-30	127	COG2059	Chromate transport protein ChrA	195
650068848	412	48.99	9	404	2	395	6.0e-94	337	COG2807	Cyanate permease	395
650068852	864	20.19	9	417	11	406	8.0e-15	76.5	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
650068853	227	50.22	3	224	1	225	7.0e-76	277	COG1136	ABC-type lipoprotein export system, ATPase component	226
650068854	312	22.62	6	171	31	196	2.0e-11	63	COG4767	Glycopeptide antibiotics resistance protein	199
650068855	333	25.23	5	328	14	327	4.0e-33	135	COG0642	Signal transduction histidine kinase	336
650068856	236	41.23	10	233	1	224	2.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650068857	264	56.65	1	263	1	263	3.0e-89	321	COG1101	ABC-type uncharacterized transport system, ATPase component	263
650068858	306	54.98	4	285	2	291	6.0e-75	274	COG4120	ABC-type uncharacterized transport system, permease component	293
650068859	345	40.79	1	331	2	312	1.0e-67	250	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
650068860	212	24.04	6	204	7	206	2.0e-14	72.6	COG2755	Lysophospholipase L1 or related esterase	216
650068861	301	47.24	3	292	1	278	8.0e-104	370	COG1054	Predicted sulfurtransferase	308
650068863	197	23.19	45	161	4	133	2.0e-03	35.6	COG1225	Peroxiredoxin	157
650068867	463	45.21	57	457	2	395	4.0e-87	315	COG1921	Seryl-tRNA(Sec) selenium transferase	395
650068868	82	40	5	73	4	73	5.0e-06	42.6	COG4844	Uncharacterized protein YuzB, UPF0349 family	78
650068869	263	36.96	6	257	2	248	4.0e-45	175	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650068870	360	39.19	10	356	5	345	1.0e-85	310	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
650068872	424	51.29	1	423	2	404	9.0e-111	393	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650068873	958	44.89	8	947	3	906	0.0e+00	1087	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
650068874	310	33.45	19	299	1	258	3.0e-52	199	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
650068875	188	31.14	25	188	3	168	4.0e-24	104	COG0622	Predicted phosphodiesterase	172
650068876	212	24.64	1	204	3	208	4.0e-14	71.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
650068877	458	34.57	1	445	4	462	3.0e-89	322	COG1113	L-asparagine transporter and related permeases	462
650068881	494	37.07	1	394	5	387	5.0e-67	248	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
650068885	894	36.33	456	731	73	329	2.0e-37	151	COG0642	Signal transduction histidine kinase	336
650068888	187	33.33	5	118	2	106	5.0e-13	67.7	COG1734	RNA polymerase-binding transcription factor DksA	120
650068890	424	18.9	52	416	46	383	1.0e-05	44.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650068891	334	29.62	2	334	1	341	4.0e-57	215	COG0673	Predicted dehydrogenase	342
650068893	395	20.7	5	372	4	332	3.0e-09	56.8	COG3274	Surface polysaccharide O-acyltransferase, integral membrane enzyme	332
650068897	265	36.68	6	260	1	248	9.0e-47	180	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650068898	279	22.76	62	275	24	247	2.0e-09	56.6	COG0631	Serine/threonine protein phosphatase PrpC	262
650068902	91	22.47	1	89	1	89	8.0e-09	52.2	COG4842	Uncharacterized conserved protein YukE	97
650068908	109	34.91	4	105	2	107	7.0e-18	82.2	COG1695	DNA-binding transcriptional regulator, PadR family	138
650068909	186	25.64	1	186	1	195	2.0e-18	85.4	COG4709	Uncharacterized membrane protein	195
650068911	208	45.85	1	205	1	202	9.0e-63	233	COG1182	FMN-dependent NADH-azoreductase	202
650068912	101	48.19	7	89	3	85	3.0e-20	90	COG3860	Uncharacterized protein	89
650068913	325	26.28	1	325	3	300	2.0e-38	152	COG0492	Thioredoxin reductase	305
650068914	147	61.9	1	147	2	148	2.0e-32	131	COG2707	Uncharacterized membrane protein, DUF441 family	151
650068915	266	24.9	14	262	44	289	2.0e-18	86.5	COG0382	4-hydroxybenzoate polyprenyltransferase	289
650068916	210	25.5	1	200	3	190	5.0e-23	101	COG0560	Phosphoserine phosphatase	212
650068920	124	31.67	5	124	2	119	3.0e-19	87.2	COG3682	Predicted transcriptional regulator	123
650068921	474	24.48	4	332	5	326	1.0e-31	131	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
650068922	556	43.42	1	555	24	567	0.0e+00	475	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650068925	101	47.37	1	95	1	95	3.0e-24	103	COG4841	Uncharacterized protein YneR	95
650068926	603	35.66	21	592	2	565	1.0e-122	434	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650068927	701	40.33	141	676	32	566	4.0e-127	449	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650068932	296	30.71	1	237	1	254	7.0e-40	157	COG1131	ABC-type multidrug transport system, ATPase component	293
650068933	160	48.72	1	155	19	174	9.0e-53	199	COG0225	Peptide methionine sulfoxide reductase MsrA	174
650068936	325	28.17	5	319	1	277	5.0e-53	201	COG0523	GTPase, G3E family	323
650068937	172	52.2	8	164	1	157	5.0e-45	173	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
650068939	333	32.12	7	330	1	324	2.0e-53	203	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650068941	484	44.62	6	379	13	378	2.0e-100	360	COG1488	Nicotinic acid phosphoribosyltransferase	405
650068942	184	32.12	1	181	5	197	1.0e-29	123	COG1335	Nicotinamidase-related amidase	205
650068943	257	44.09	42	167	16	141	1.0e-26	113	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650068944	149	40.17	24	140	4	120	1.0e-15	76.2	COG4550	Cell fate regulator YmcA, YheA/YmcA/DUF963 family (controls sporulation, competence, biofilm development)	120
650068945	519	48.53	74	509	4	436	0.0e+00	523	COG0621	tRNA A37 methylthiotransferase MiaB	437
650068946	190	58.6	5	189	23	208	3.0e-64	237	COG4869	Propanediol utilization protein	210
650068949	86	82.56	1	86	1	86	2.0e-31	127	COG2359	Stage V sporulation protein SpoVS  (function unknown)	87
650068950	267	54.79	4	263	1	261	1.0e-99	356	COG1692	Calcineurin-like phosphoesterase	266
650068951	514	56.5	293	514	1	222	2.0e-51	196	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
650068952	245	34.29	64	237	1	174	4.0e-21	95.4	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
650068953	353	63.73	1	280	4	279	1.0e-85	309	COG0468	RecA/RadA recombinase	279
650068954	420	46.64	1	250	2	252	1.0e-70	260	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
650068955	195	37.63	1	191	12	189	6.0e-21	93.9	COG0558	Phosphatidylglycerophosphate synthase	192
650068956	163	52.44	1	163	1	164	9.0e-48	182	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
650068958	319	24.53	1	254	1	262	1.0e-28	120	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
650068961	256	39.76	15	255	6	251	4.0e-49	188	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650068962	426	28.8	6	423	1	428	2.0e-70	260	COG0612	Predicted Zn-dependent peptidase	438
650068963	426	24.07	10	426	22	434	2.0e-42	167	COG0612	Predicted Zn-dependent peptidase	438
650068965	370	38.5	8	367	1	355	3.0e-91	328	COG4225	Rhamnogalacturonyl hydrolase YesR	357
650068966	504	52.03	113	504	3	381	0.0e+00	470	COG2721	Altronate dehydratase	381
650068967	505	28.31	20	503	2	464	4.0e-78	285	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
650068968	285	36.13	165	283	5	123	1.0e-19	90.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650068970	258	23.5	59	239	31	197	2.0e-27	116	COG0740	ATP-dependent protease ClpP, protease subunit	200
650068971	559	55.73	2	557	1	555	0.0e+00	672	COG0595	mRNA degradation ribonuclease J1/J2	555
650068972	293	46.74	1	288	3	288	5.0e-79	287	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650068973	404	36.68	1	402	1	446	9.0e-101	360	COG0527	Aspartokinase	447
650068978	147	60	8	147	9	147	6.0e-50	190	COG0756	dUTPase	148
650068979	422	38.72	1	409	17	437	1.0e-94	340	COG0612	Predicted Zn-dependent peptidase	438
650068980	701	60.55	1	692	3	691	0.0e+00	971	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
650068981	89	67.42	1	89	1	89	2.0e-27	114	COG0184	Ribosomal protein S15P/S13E	89
650068982	317	41.4	1	314	1	304	4.0e-84	304	COG0196	FAD synthase	304
650068983	303	35.43	1	302	11	269	2.0e-60	225	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
650068984	325	32.93	5	325	3	328	7.0e-52	197	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
650068985	117	57.41	5	111	6	113	3.0e-30	123	COG0858	Ribosome-binding factor A	118
650068987	806	66.82	389	806	1	422	0.0e+00	610	COG0532	Translation initiation factor IF-2, a GTPase	509
650068988	108	36.79	1	105	11	116	5.0e-16	76.1	COG1358	Ribosomal protein L7Ae or related RNA K-turn-binding protein	116
650068989	103	50.6	1	83	1	83	2.0e-18	84.2	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
650068990	365	53.12	156	346	1	186	2.0e-47	183	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
650068991	153	45.75	1	153	1	153	7.0e-43	166	COG0779	Ribosome maturation factor RimP	153
650068992	485	32.41	7	485	4	499	4.0e-115	408	COG0442	Prolyl-tRNA synthetase	500
650068993	424	30.56	149	423	77	375	6.0e-34	138	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
650068994	379	57.82	1	376	1	376	0.0e+00	540	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
650068995	266	36.7	1	266	2	265	1.0e-34	140	COG0575	CDP-diglyceride synthetase	265
650068996	184	63.78	1	184	3	187	3.0e-63	234	COG0233	Ribosome recycling factor	187
650068997	242	64.29	2	239	1	238	9.0e-97	346	COG0528	Uridylate kinase	238
650069002	469	34.89	2	463	67	530	3.0e-70	259	COG1315	Uncharacterized conserved protein, DUF342 family	543
650069003	262	37.55	12	254	11	247	2.0e-41	163	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
650069005	165	48.43	7	165	9	164	4.0e-44	170	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
650069006	208	36.45	1	203	1	201	2.0e-36	145	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
650069007	153	44.59	1	148	14	160	5.0e-33	133	COG0835	Chemotaxis signal transduction protein	165
650069009	296	35.82	31	294	4	261	3.0e-49	189	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
650069010	479	36.15	185	476	101	396	4.0e-63	235	COG1419	Flagellar biosynthesis GTPase FlhF	407
650069011	677	55.15	1	677	16	695	0.0e+00	834	COG1298	Flagellar biosynthesis pathway, component FlhA	696
650069012	316	46.01	4	316	43	355	9.0e-97	346	COG1377	Flagellar biosynthesis protein FlhB	363
650069013	262	37.5	11	258	15	258	6.0e-42	164	COG1684	Flagellar biosynthesis protein FliR	258
650069014	89	52.81	1	89	1	89	7.0e-17	79	COG1987	Flagellar biosynthesis protein FliQ	89
650069015	250	56.28	3	249	2	248	2.0e-71	262	COG1338	Flagellar biosynthetic protein FliP	248
650069016	174	22.03	19	133	22	136	4.0e-06	44.9	COG3190	Flagellar biogenesis protein FliO	137
650069018	419	35.2	37	231	7	201	1.0e-34	140	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
650069019	154	20.83	1	142	13	148	6.0e-05	40.6	COG1580	Flagellar basal body-associated protein FliL	159
650069020	74	55	1	60	1	60	3.0e-14	70.3	COG1582	Uncharacterized protein YlzI, FlbEa/FlbD family	67
650069021	274	41.16	1	274	1	265	3.0e-60	225	COG4786	Flagellar basal body rod protein FlgG	265
650069024	447	19.27	10	414	16	399	1.0e-12	68.2	COG3144	Flagellar hook-length control protein FliK	417
650069025	308	27.66	20	207	10	182	2.0e-08	53.9	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
650069026	147	26.03	1	146	1	146	2.0e-08	51.8	COG2882	Flagellar biosynthesis chaperone FliJ	148
650069027	439	60.09	7	437	10	440	0.0e+00	611	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
650069028	284	25.85	63	266	27	224	9.0e-12	64.2	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
650069029	331	51.98	2	329	11	339	1.0e-90	326	COG1536	Flagellar motor switch protein FliG	339
650069030	102	31.07	1	102	3	105	2.0e-10	57.6	COG1677	Flagellar hook-basal body complex protein FliE	105
650069031	149	48.99	1	149	1	137	4.0e-42	163	COG1558	Flagellar basal body rod protein FlgC	137
650069032	135	40	6	135	5	133	2.0e-25	108	COG1815	Flagellar basal body rod protein FlgB	133
650069033	468	59.87	3	468	1	444	0.0e+00	629	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
650069034	180	63.84	4	180	1	175	1.0e-69	255	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
650069035	442	71.49	2	434	1	435	0.0e+00	738	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
650069036	669	41.09	531	654	1	129	1.0e-28	121	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
650069036	669	50.63	1	548	29	570	0.0e+00	625	COG0550	DNA topoisomerase IA	570
650069037	391	34.79	4	391	5	350	6.0e-82	298	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
650069038	309	66.23	1	301	1	293	2.0e-117	415	COG0074	Succinyl-CoA synthetase, alpha subunit	293
650069039	386	61.34	1	386	1	385	0.0e+00	537	COG0045	Succinyl-CoA synthetase, beta subunit	387
650069045	532	49.41	14	522	1	489	0.0e+00	569	COG0606	Predicted ATPase with chaperone activity	490
650069046	144	23.29	1	128	12	157	1.0e-05	42.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650069047	118	14.71	9	117	3	138	8.0e-03	32.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650069048	127	39.83	11	127	1	112	7.0e-26	109	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
650069049	103	51.72	12	98	5	91	7.0e-21	91.8	COG2257	Type III secretion system substrate exporter, FlhB-like	92
650069051	205	54.95	17	193	1	181	5.0e-55	207	COG0164	Ribonuclease HII	199
650069052	288	43.49	1	288	12	299	7.0e-71	260	COG1161	Ribosome biogenesis GTPase A	322
650069053	204	26.58	19	173	1	157	9.0e-10	56.9	COG0681	Signal peptidase I	166
650069054	115	75.22	2	114	3	115	3.0e-41	159	COG0335	Ribosomal protein L19	115
650069058	271	53.76	1	265	1	240	6.0e-105	373	COG0336	tRNA G37 N-methylase TrmD	240
650069059	173	45.35	3	173	5	173	6.0e-41	160	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
650069060	76	50.67	1	75	1	75	2.0e-16	77.5	COG1837	Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family	76
650069061	90	62.07	2	87	1	87	2.0e-28	117	COG0228	Ribosomal protein S16	87
650069062	460	58.08	2	459	1	451	0.0e+00	613	COG0541	Signal recognition particle GTPase	451
650069063	118	54.65	7	92	1	86	3.0e-17	80.3	COG2739	Predicted DNA-binding protein YlxM, UPF0122 family	105
650069064	233	52.8	22	232	13	226	3.0e-45	175	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
650069065	354	50.56	1	351	19	374	4.0e-111	394	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
650069068	336	17.2	1	312	1	363	2.0e-09	56.9	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
650069071	333	53.24	1	319	1	340	1.0e-106	379	COG0552	Signal recognition particle GTPase	340
650069072	1189	41.5	1	1188	1	1163	0.0e+00	694	COG1196	Chromosome segregation ATPase	1163
650069073	232	53.1	4	228	7	230	6.0e-73	267	COG0571	dsRNA-specific ribonuclease	235
650069074	412	56.76	1	410	1	411	0.0e+00	516	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
650069075	77	57.14	1	77	3	79	3.0e-11	60.3	COG0236	Acyl carrier protein	80
650069076	249	53.39	5	247	3	250	6.0e-53	200	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650069077	310	55.66	1	307	1	308	7.0e-100	357	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
650069078	329	56.35	7	329	4	322	1.0e-119	422	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
650069079	328	54.22	1	327	2	333	8.0e-118	416	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
650069080	134	20.8	11	130	15	136	7.0e-07	46.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
650069082	57	55.36	1	56	1	56	2.0e-14	70.7	COG0333	Ribosomal protein L32	57
650069083	169	27.38	4	169	8	175	4.0e-19	87.7	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
650069084	411	38.08	1	363	1	350	1.0e-69	257	COG1323	Predicted nucleotidyltransferase	358
650069086	310	36.25	1	308	1	298	4.0e-54	205	COG3480	Predicted secreted protein containing a PDZ domain	342
650069088	171	59.24	10	166	3	159	8.0e-63	232	COG0669	Phosphopantetheine adenylyltransferase	159
650069089	205	45.16	5	187	2	186	3.0e-49	188	COG0742	16S rRNA G966 N2-methylase RsmD	187
650069096	223	19.91	9	213	29	237	1.0e-04	40	COG4700	Uncharacterized protein	251
650069097	192	23.68	2	183	28	204	5.0e-12	64.6	COG2755	Lysophospholipase L1 or related esterase	216
650069099	149	29.46	30	141	12	123	2.0e-13	68.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
650069100	238	51.33	3	227	2	227	9.0e-77	280	COG0120	Ribose 5-phosphate isomerase	227
650069102	191	49.42	7	176	1	168	5.0e-42	164	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
650069106	336	43.2	2	335	1	332	1.0e-86	313	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650069107	402	24.1	8	344	18	377	2.0e-19	90.6	COG2211	Na+/melibiose symporter or related transporter	467
650069108	245	37.8	4	243	6	257	3.0e-49	188	COG0584	Glycerophosphoryl diester phosphodiesterase	257
650069109	154	30.58	21	141	7	124	4.0e-14	71.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
650069110	414	18.84	1	395	1	390	2.0e-12	67.2	COG2814	Predicted arabinose efflux permease, MFS family	394
650069111	376	56.54	1	301	1	305	3.0e-112	398	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
650069112	218	62.14	9	214	12	217	1.0e-54	206	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
650069113	296	41.34	11	287	4	282	2.0e-70	259	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
650069114	429	22.08	8	400	15	390	1.0e-25	111	COG2814	Predicted arabinose efflux permease, MFS family	394
650069115	567	28.86	160	553	33	408	2.0e-37	150	COG0840	Methyl-accepting chemotaxis protein	408
650069117	775	31.54	8	767	8	747	0.0e+00	507	COG3973	DNA helicase IV	747
650069118	352	26.35	1	289	7	296	1.0e-35	143	COG4129	Uncharacterized membrane protein YgaE, UPF0421/DUF939 family	332
650069123	350	32.53	21	304	18	298	2.0e-32	133	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
650069124	329	45.89	12	327	32	345	8.0e-90	323	COG0709	Selenophosphate synthase	346
650069125	355	28.67	75	355	17	316	1.0e-36	147	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
650069126	399	23.05	101	376	29	303	6.0e-14	72.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
650069133	575	39.12	11	550	1	530	0.0e+00	497	COG0578	Glycerol-3-phosphate dehydrogenase	532
650069134	496	67.54	1	496	3	497	0.0e+00	820	COG0554	Glycerol kinase	499
650069135	298	31.74	2	291	30	309	3.0e-39	155	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
650069137	419	30.18	1	414	1	430	3.0e-47	182	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069138	312	40.82	21	312	3	294	2.0e-60	226	COG1175	ABC-type sugar transport system, permease component	295
650069139	278	44.29	3	277	2	281	8.0e-64	237	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069140	320	23.39	1	319	3	341	5.0e-36	144	COG0673	Predicted dehydrogenase	342
650069141	474	46.72	4	474	1	469	0.0e+00	528	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650069142	324	52.16	2	324	1	320	3.0e-103	368	COG4607	ABC-type enterochelin transport system, periplasmic component	320
650069143	252	64.54	1	251	1	251	2.0e-107	381	COG4604	ABC-type enterochelin transport system, ATPase component	252
650069144	315	58.33	4	315	5	316	5.0e-89	321	COG4605	ABC-type enterochelin transport system, permease component	316
650069145	317	61.71	1	316	5	320	3.0e-109	388	COG4606	ABC-type enterochelin transport system, permease component	321
650069146	200	61.81	1	199	2	199	6.0e-78	283	COG3560	Fatty acid repression mutant protein (predicted oxidoreductase)	200
650069150	162	34.97	1	161	21	182	5.0e-20	90.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650069155	377	26.63	45	365	66	371	1.0e-28	120	COG0840	Methyl-accepting chemotaxis protein	408
650069157	186	28.5	1	178	2	194	6.0e-25	107	COG0406	Broad specificity phosphatase PhoE	208
650069158	150	29.46	5	133	9	127	5.0e-14	70.4	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650069162	182	45.2	8	181	9	184	2.0e-39	155	COG3575	Uncharacterized protein	184
650069163	303	40.84	3	301	1	307	4.0e-51	195	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650069165	460	23.53	16	313	14	298	5.0e-15	76.1	COG1397	ADP-ribosylglycohydrolase	314
650069166	386	24.3	1	353	1	305	5.0e-25	108	COG1397	ADP-ribosylglycohydrolase	314
650069167	497	22.19	1	368	1	340	8.0e-12	65.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069168	290	33.11	2	289	5	281	2.0e-43	169	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069169	297	43	1	297	10	309	7.0e-77	280	COG4209	ABC-type polysaccharide transport system, permease component	309
650069172	232	41.2	1	227	1	233	5.0e-43	167	COG2186	DNA-binding transcriptional regulator, FadR family	241
650069176	355	24.3	1	353	1	341	1.0e-44	173	COG0673	Predicted dehydrogenase	342
650069178	124	44.54	4	119	5	121	4.0e-25	106	COG4288	Uncharacterized protein	124
650069179	365	21.49	145	360	11	216	5.0e-13	69.2	COG2755	Lysophospholipase L1 or related esterase	216
650069181	512	26.64	1	512	1	473	2.0e-58	220	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650069182	446	21.26	41	443	23	432	7.0e-34	138	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069183	299	41.5	1	291	1	290	4.0e-57	215	COG1175	ABC-type sugar transport system, permease component	295
650069184	277	41.67	3	276	8	281	8.0e-59	220	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069185	349	41.64	6	343	5	351	6.0e-96	344	COG4225	Rhamnogalacturonyl hydrolase YesR	357
650069186	205	37.5	63	193	5	138	3.0e-22	98.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650069191	403	26.59	1	403	1	381	6.0e-39	155	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650069193	367	19.29	1	364	1	385	4.0e-11	62.6	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
650069195	297	33.11	1	295	1	291	6.0e-73	267	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
650069196	305	42.24	3	300	1	300	2.0e-81	295	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
650069197	218	58.74	9	214	12	217	4.0e-54	204	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
650069198	377	54.98	1	303	1	307	3.0e-110	391	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
650069201	369	15.86	1	280	2	291	1.0e-11	64.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650069206	194	37.44	1	192	12	189	1.0e-20	93.5	COG0558	Phosphatidylglycerophosphate synthase	192
650069208	114	22.14	6	111	3	131	1.0e-04	38.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650069209	170	30.28	13	119	15	123	1.0e-08	53.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650069210	217	44.39	1	204	2	205	9.0e-55	206	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
650069211	500	48.29	1	497	4	497	0.0e+00	488	COG3333	TctA family transporter	504
650069213	270	36.73	1	270	45	318	3.0e-55	208	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650069214	253	46.12	3	247	1	245	1.0e-71	263	COG1414	DNA-binding transcriptional regulator, IclR family	246
650069215	276	30.52	45	194	21	174	3.0e-23	102	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650069216	193	64.58	1	192	1	192	3.0e-75	274	COG0740	ATP-dependent protease ClpP, protease subunit	200
650069218	303	16.99	6	252	17	268	4.0e-08	52.3	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
650069220	103	21.05	1	93	2	96	1.0e-13	68.1	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
650069221	117	37.96	1	107	5	111	2.0e-21	94.6	COG3502	Uncharacterized conserved protein, DUF952 family	115
650069222	229	21.1	8	217	26	240	7.0e-15	74.2	COG4242	Cyanophycinase and related exopeptidases	293
650069224	335	23.51	40	321	50	318	3.0e-18	86.2	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
650069225	182	22.94	58	166	35	136	2.0e-06	45.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650069226	564	22.18	6	561	19	594	6.0e-78	285	COG1164	Oligoendopeptidase F	598
650069227	104	39.42	1	104	2	105	3.0e-14	70.1	COG2076	Multidrug transporter EmrE and related cation transporters	106
650069228	115	42.72	5	104	4	106	2.0e-16	77.4	COG2076	Multidrug transporter EmrE and related cation transporters	106
650069229	288	32.07	1	279	1	288	8.0e-37	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
650069230	184	32.4	10	183	1	179	2.0e-30	125	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650069231	286	26.18	1	275	1	259	1.0e-33	137	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
650069233	219	23.38	1	214	2	227	3.0e-17	82.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
650069235	134	29.93	7	133	18	149	2.0e-06	45.1	COG1714	Uncharacterized membrane protein YckC, RDD family	172
650069238	158	26.53	4	148	8	145	2.0e-13	68.5	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650069239	304	17.75	1	299	2	341	4.0e-09	55.6	COG0673	Predicted dehydrogenase	342
650069243	262	48.68	1	226	28	255	2.0e-73	269	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
650069245	249	22.36	7	249	10	228	3.0e-15	75.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650069246	312	20.55	11	283	11	279	1.0e-07	50.4	COG2017	Galactose mutarotase or related enzyme	308
650069248	297	35.34	177	292	4	119	2.0e-20	93	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650069250	703	31.18	12	697	4	682	5.0e-112	399	COG3345	Alpha-galactosidase	687
650069251	537	23.06	1	383	1	349	5.0e-18	86.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069252	612	30.42	256	597	111	455	2.0e-38	154	COG2972	Sensor histidine kinase YesM	456
650069253	325	45.13	19	325	9	309	2.0e-84	305	COG4209	ABC-type polysaccharide transport system, permease component	309
650069254	297	29.87	5	296	3	281	1.0e-42	166	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069263	365	22.35	9	353	2	312	6.0e-30	124	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650069264	346	36.34	17	344	1	332	9.0e-52	197	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
650069265	343	38.65	17	340	20	345	7.0e-54	204	COG4779	ABC-type enterobactin transport system, permease component	346
650069266	271	50	5	262	1	258	5.0e-92	330	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
650069274	420	44.26	7	67	1	61	3.0e-11	63.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
650069276	494	21.85	30	289	2	254	2.0e-20	94.3	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
650069277	501	32.34	47	382	16	298	7.0e-54	205	COG2421	Acetamidase/formamidase	305
650069282	147	19.26	2	134	26	159	2.0e-05	41.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650069285	512	28.12	152	501	17	336	7.0e-39	155	COG0642	Signal transduction histidine kinase	336
650069286	231	44.74	3	225	2	224	3.0e-60	224	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650069288	246	28.3	1	199	4	202	5.0e-24	104	COG0300	Short-chain dehydrogenase	265
650069291	255	29.44	38	243	37	242	6.0e-28	117	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
650069295	267	37.66	1	237	6	242	5.0e-62	231	COG0796	Glutamate racemase	269
650069296	516	20.59	10	340	22	321	2.0e-04	41.1	COG1565	SAM-dependent methyltransferase, MidA family	370
650069299	140	19.12	5	128	3	138	9.0e-08	49.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650069300	155	26.83	1	153	3	165	2.0e-22	98.1	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650069302	457	25.83	10	328	10	322	3.0e-33	136	COG3669	Alpha-L-fucosidase	430
650069303	490	12.44	19	419	19	422	3.0e-12	67	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069306	308	40.59	1	303	5	305	2.0e-78	285	COG4209	ABC-type polysaccharide transport system, permease component	309
650069307	292	32.54	1	291	3	281	6.0e-45	174	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069308	213	26.95	39	200	14	180	1.0e-25	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650069311	252	43.75	4	225	1	223	2.0e-61	228	COG1136	ABC-type lipoprotein export system, ATPase component	226
650069313	194	19.14	1	162	25	186	2.0e-12	65.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650069315	257	43.63	3	254	2	250	2.0e-47	182	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650069316	245	40.94	2	243	1	251	4.0e-48	185	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650069319	172	18.38	27	162	23	143	4.0e-03	34.6	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650069320	393	38.62	1	232	1	241	3.0e-51	196	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
650069326	280	24.73	4	272	3	275	3.0e-26	112	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650069327	319	34.19	1	314	70	454	2.0e-59	223	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
650069330	141	31.4	1	111	3	123	5.0e-17	80.5	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650069333	884	29.58	87	641	127	646	5.0e-94	339	COG0209	Ribonucleotide reductase alpha subunit	696
650069339	267	30.33	36	266	14	230	4.0e-31	128	COG0860	N-acetylmuramoyl-L-alanine amidase	231
650069340	742	28.12	353	736	40	408	5.0e-44	173	COG0840	Methyl-accepting chemotaxis protein	408
650069341	295	41.67	57	283	24	246	2.0e-54	206	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
650069345	109	29.17	7	102	16	111	3.0e-12	63.5	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
650069348	189	32.78	1	180	5	179	1.0e-26	113	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
650069349	337	31.83	8	317	6	314	7.0e-47	181	COG3949	Uncharacterized membrane protein YkvI	349
650069350	435	24.23	5	308	2	311	5.0e-36	145	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
650069351	359	36.18	62	353	75	377	1.0e-33	137	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650069353	461	34.21	3	283	51	353	2.0e-61	229	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
650069354	188	27.43	1	169	1	172	1.0e-26	112	COG0431	NAD(P)H-dependent FMN reductase	184
650069355	357	21.08	26	343	3	334	2.0e-36	146	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650069358	75	50.79	1	63	2	64	2.0e-16	77	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
650069359	325	58.69	1	213	1	213	4.0e-80	291	COG1535	Isochorismate hydrolase	218
650069360	550	59.93	1	539	4	537	0.0e+00	750	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
650069361	414	36.67	25	404	46	422	2.0e-96	346	COG1169	Isochorismate synthase EntC	423
650069362	261	40.86	6	256	3	249	2.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650069363	280	34.63	26	279	15	262	1.0e-45	176	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
650069364	356	26.78	65	353	19	312	1.0e-37	150	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650069365	405	24.81	126	383	53	308	3.0e-27	116	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650069366	266	30.08	1	265	1	262	6.0e-44	171	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
650069367	253	47.18	10	253	4	247	6.0e-66	244	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
650069368	537	36.51	5	312	54	355	5.0e-72	265	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
650069369	175	25.47	47	147	4	108	2.0e-06	45.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650069371	147	27.66	11	144	18	154	2.0e-09	55	COG1547	Predicted metal-dependent hydrolase	156
650069372	270	53.81	1	208	13	222	2.0e-61	229	COG2357	ppGpp synthetase catalytic domain (RelA/SpoT-type nucleotidyltranferase)	231
650069373	366	43.61	53	366	1	309	2.0e-85	309	COG0167	Dihydroorotate dehydrogenase	310
650069376	79	52.11	3	73	1	68	2.0e-12	64.2	COG1141	Ferredoxin	68
650069377	447	42.06	13	365	1	354	5.0e-86	311	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
650069378	272	19.63	15	227	30	236	1.0e-10	60.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650069379	538	35.7	3	423	1	409	2.0e-100	360	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
650069380	183	31.15	41	161	4	123	1.0e-12	66.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650069381	177	30.43	10	121	1	107	3.0e-08	51.7	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
650069384	471	44.29	29	445	3	407	6.0e-96	344	COG0004	Ammonia channel protein AmtB	409
650069385	150	35.96	11	118	1	114	7.0e-14	70.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
650069386	226	57.52	1	226	1	226	1.0e-86	312	COG2738	Zn-dependent membrane protease YugP	226
650069387	311	35.14	1	294	1	292	5.0e-46	178	COG0583	DNA-binding transcriptional regulator, LysR family	297
650069388	204	33.94	1	204	2	217	3.0e-16	78.6	COG0705	Membrane associated serine protease, rhomboid family	228
650069390	172	58.06	10	161	5	158	3.0e-56	210	COG2077	Peroxiredoxin	158
650069393	276	29.29	11	247	1	208	1.0e-24	107	COG5578	Uncharacterized membrane protein YesL	208
650069395	536	46.12	1	477	28	509	2.0e-124	439	COG0513	Superfamily II DNA and RNA helicase	513
650069396	273	36.56	1	273	9	287	2.0e-50	193	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
650069398	394	41.27	70	387	64	386	2.0e-61	230	COG1306	Uncharacterized protein	400
650069400	391	30.65	1	385	74	454	9.0e-52	197	COG0534	Na+-driven multidrug efflux pump	455
650069401	323	50.29	5	323	3	342	1.0e-101	363	COG0205	6-phosphofructokinase	347
650069403	379	19.57	1	369	22	391	6.0e-05	42.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650069404	65	63.64	1	65	2	67	2.0e-21	93.7	COG1278	Cold shock protein, CspA family	67
650069408	519	44.38	1	519	75	597	0.0e+00	475	COG1164	Oligoendopeptidase F	598
650069409	109	40.51	1	78	20	98	6.0e-13	65.7	COG5416	Uncharacterized integral membrane protein	98
650069410	345	33.43	9	345	2	344	3.0e-84	305	COG1363	Putative aminopeptidase FrvX	355
650069411	651	42.3	1	530	1	527	0.0e+00	528	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650069412	268	25.65	1	267	11	247	6.0e-27	114	COG1836	Uncharacterized membrane protein	247
650069413	207	38.78	5	194	59	250	5.0e-42	164	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
650069414	257	35.39	6	234	9	248	2.0e-38	152	COG0584	Glycerophosphoryl diester phosphodiesterase	257
650069415	438	31.06	159	431	82	371	5.0e-32	132	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
650069416	313	33.64	1	307	2	314	8.0e-71	260	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
650069417	352	48.71	1	343	4	351	7.0e-107	380	COG0407	Uroporphyrinogen-III decarboxylase	352
650069418	403	19.24	8	401	15	394	1.0e-18	88	COG2814	Predicted arabinose efflux permease, MFS family	394
650069419	210	40.48	6	210	13	218	2.0e-36	145	COG4122	Predicted O-methyltransferase YrrM	219
650069420	382	46.05	3	377	2	381	7.0e-116	410	COG0116	23S rRNA G2445 N2-methylase RlmL	381
650069421	661	29.28	25	656	29	640	2.0e-85	310	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
650069423	486	27.91	2	354	6	371	1.0e-45	177	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650069425	106	33.33	2	101	16	117	7.0e-13	65.6	COG1695	DNA-binding transcriptional regulator, PadR family	138
650069428	100	33.33	5	92	7	96	1.0e-08	51.4	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
650069430	400	17.47	114	391	112	374	2.0e-11	63.9	COG2866	Murein tripeptide amidase MpaA	374
650069431	268	47.24	1	253	4	256	9.0e-83	300	COG0796	Glutamate racemase	269
650069432	365	60.17	10	363	7	348	0.0e+00	473	COG4362	Nitric oxide synthase, oxygenase domain	355
650069435	140	29.71	2	139	1	136	2.0e-12	65.3	COG2445	Uncharacterized conserved protein YutE, UPF0331/DUF86 family	138
650069437	478	43	1	478	16	485	0.0e+00	472	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
650069448	227	26.89	11	205	6	210	2.0e-09	56.4	COG3714	Uncharacterized membrane protein YhhN	212
650069449	237	37.23	4	234	3	220	3.0e-42	165	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
650069452	270	43.02	1	262	5	268	2.0e-60	225	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
650069453	587	40.73	10	548	1	532	1.0e-128	453	COG0578	Glycerol-3-phosphate dehydrogenase	532
650069454	302	34.21	189	302	8	121	4.0e-21	95.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650069455	352	35.93	1	352	1	340	7.0e-68	250	COG0673	Predicted dehydrogenase	342
650069456	285	25.95	1	284	3	274	3.0e-26	112	COG1082	Sugar phosphate isomerase/epimerase	274
650069457	298	23.97	14	295	10	270	2.0e-21	96.1	COG1082	Sugar phosphate isomerase/epimerase	274
650069458	305	26.21	1	281	3	277	1.0e-40	160	COG0673	Predicted dehydrogenase	342
650069459	295	30.65	4	254	2	251	3.0e-27	115	COG1082	Sugar phosphate isomerase/epimerase	274
650069461	402	44.67	6	389	1	393	2.0e-109	389	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650069462	332	39.74	1	293	3	314	5.0e-70	258	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
650069463	485	31.81	10	485	2	458	2.0e-95	343	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650069466	474	26.53	7	469	5	430	2.0e-53	203	COG3669	Alpha-L-fucosidase	430
650069467	522	25.41	8	367	16	349	4.0e-20	93.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069468	298	35.74	13	297	8	281	4.0e-42	165	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069469	322	44.01	17	322	1	309	3.0e-87	315	COG4209	ABC-type polysaccharide transport system, permease component	309
650069481	362	28.83	121	338	46	265	3.0e-25	109	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
650069487	97	31.82	1	64	1	66	7.0e-06	42.3	COG2002	Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module	89
650069495	305	28.57	8	297	2	291	4.0e-38	151	COG4974	Site-specific recombinase XerD	300
650069496	965	42.77	628	950	1	322	2.0e-78	288	COG4644	Transposase and inactivated derivatives, TnpA family	323
650069502	235	30.56	29	228	81	295	5.0e-27	114	COG4974	Site-specific recombinase XerD	300
650069507	186	30.58	2	186	39	228	1.0e-20	92.8	COG0860	N-acetylmuramoyl-L-alanine amidase	231
650069511	530	38.81	1	514	4	489	3.0e-93	336	COG0286	Type I restriction-modification system, DNA methylase subunit	489
650069512	389	19.44	18	388	1	388	6.0e-24	105	COG0732	Restriction endonuclease S subunit	391
650069513	1051	26.05	6	988	1	907	1.0e-88	322	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
650069517	220	36.61	4	183	2	184	4.0e-41	161	COG4185	Predicted ABC-type ATPase	187
650069527	73	35	2	61	5	60	8.0e-04	35.6	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
650069530	640	31.38	4	539	49	558	1.0e-93	337	COG0550	DNA topoisomerase IA	570
650069539	322	23.68	2	316	1	314	3.0e-34	139	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650069540	396	49.09	8	390	5	388	2.0e-127	449	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
650069541	300	21.78	1	299	1	292	6.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
650069546	833	48.17	129	831	227	932	0.0e+00	860	COG0178	Excinuclease UvrABC ATPase subunit	935
650069549	453	28.63	2	448	1	433	1.0e-50	194	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069550	274	40.36	4	273	7	281	7.0e-54	204	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069551	308	41.3	17	308	2	294	4.0e-57	215	COG1175	ABC-type sugar transport system, permease component	295
650069553	219	33.95	1	212	2	215	3.0e-34	138	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650069554	426	52.12	47	424	2	379	2.0e-104	373	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650069555	166	27.78	1	161	2	163	1.0e-15	76.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650069556	328	40.24	3	324	2	326	4.0e-83	301	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650069557	341	38.29	1	340	2	350	6.0e-70	258	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650069558	218	30.56	2	216	4	218	1.0e-31	130	COG1802	DNA-binding transcriptional regulator, GntR family	230
650069559	463	28.44	6	455	1	410	3.0e-61	229	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
650069560	397	40.09	183	391	1	208	2.0e-52	200	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
650069562	143	31.43	34	138	19	123	3.0e-12	64.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
650069564	224	38.5	12	208	12	207	5.0e-42	164	COG4122	Predicted O-methyltransferase YrrM	219
650069565	295	31.53	1	294	1	290	7.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
650069567	349	28.77	10	300	7	292	8.0e-33	134	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650069568	329	38.24	13	316	2	305	2.0e-52	199	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650069569	350	40.38	28	338	3	311	2.0e-56	213	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650069570	504	49.8	1	496	4	500	0.0e+00	619	COG1129	ABC-type sugar transport system, ATPase component	500
650069572	252	48.7	9	234	10	226	6.0e-68	250	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
650069573	542	21.32	4	539	2	475	5.0e-44	172	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650069575	350	31.82	52	314	33	296	9.0e-42	164	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650069576	309	29.93	21	308	6	281	2.0e-41	163	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069577	303	41.91	1	303	7	309	3.0e-81	295	COG4209	ABC-type polysaccharide transport system, permease component	309
650069578	114	44.44	19	108	15	104	1.0e-22	98.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650069579	389	35.34	3	382	12	391	2.0e-52	199	COG2814	Predicted arabinose efflux permease, MFS family	394
650069583	359	41.46	1	353	4	352	2.0e-92	333	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
650069584	570	27.57	11	564	14	539	7.0e-45	175	COG1178	ABC-type Fe3+ transport system, permease component	540
650069585	373	26.85	80	366	1	292	8.0e-25	108	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
650069586	307	31.67	1	299	1	295	5.0e-40	158	COG0583	DNA-binding transcriptional regulator, LysR family	297
650069587	453	28.25	11	451	10	404	3.0e-55	209	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650069588	379	37.24	1	379	2	350	2.0e-77	283	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650069593	330	26.75	1	320	4	311	3.0e-36	145	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650069594	90	24.44	1	89	11	100	1.0e-06	44.6	COG1359	Quinol monooxygenase YgiN	100
650069595	275	34.75	158	275	5	122	5.0e-24	104	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650069596	449	26.8	32	347	1	321	6.0e-34	139	COG3669	Alpha-L-fucosidase	430
650069597	119	20.87	9	114	14	124	1.0e-05	41.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
650069598	277	34.41	1	273	1	279	2.0e-49	189	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069599	296	36.21	10	295	4	288	1.0e-47	183	COG1175	ABC-type sugar transport system, permease component	295
650069600	466	27.17	40	457	23	429	4.0e-35	142	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069601	162	52.53	3	159	2	158	2.0e-38	152	COG5500	Uncharacterized membrane protein	159
650069604	410	25.7	36	410	24	401	1.0e-29	124	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
650069606	295	31.54	1	294	1	294	6.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
650069608	617	39.41	27	602	2	567	2.0e-127	449	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650069609	554	37.18	1	546	36	567	5.0e-111	395	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650069610	278	17.43	53	270	42	252	7.0e-06	44.8	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
650069611	313	37.94	1	309	1	293	2.0e-71	262	COG1131	ABC-type multidrug transport system, ATPase component	293
650069612	272	30.13	1	212	1	229	1.0e-26	113	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
650069613	300	29.74	1	297	5	310	2.0e-41	163	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650069615	539	18.91	56	448	16	402	2.0e-15	77.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069616	294	33.33	9	293	8	281	1.0e-47	183	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069617	319	47.99	22	319	12	309	5.0e-95	341	COG4209	ABC-type polysaccharide transport system, permease component	309
650069618	346	33.82	2	340	1	328	8.0e-65	241	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650069619	394	33.25	5	387	13	394	1.0e-56	213	COG2814	Predicted arabinose efflux permease, MFS family	394
650069620	91	27.47	1	91	10	98	4.0e-06	42.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650069622	356	57.24	75	356	1	283	4.0e-107	381	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
650069624	318	38	13	311	2	287	7.0e-52	197	COG3481	3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation,  HD superfamily	287
650069626	236	27.52	122	230	1	108	2.0e-12	66.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
650069628	285	27.5	52	131	20	99	3.0e-04	39.7	COG2076	Multidrug transporter EmrE and related cation transporters	106
650069629	373	21.45	40	365	35	355	9.0e-07	48.4	COG4225	Rhamnogalacturonyl hydrolase YesR	357
650069632	503	21.35	1	367	2	351	9.0e-18	85.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069633	336	49.84	32	336	5	309	1.0e-102	366	COG4209	ABC-type polysaccharide transport system, permease component	309
650069634	754	34.43	633	753	2	123	2.0e-22	101	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650069635	305	38.24	1	299	1	300	5.0e-65	241	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650069636	451	41.82	13	451	12	450	3.0e-112	399	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
650069638	448	31.96	1	446	3	459	5.0e-91	328	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650069640	221	27.05	1	207	2	196	2.0e-22	99.1	COG2364	Uncharacterized membrane protein YczE	210
650069646	284	26.33	1	273	1	296	7.0e-24	104	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650069647	239	29.19	1	201	6	207	2.0e-30	125	COG0300	Short-chain dehydrogenase	265
650069648	531	61.33	21	531	18	528	0.0e+00	755	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
650069650	336	48.8	5	333	4	334	6.0e-107	380	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
650069651	381	34.64	1	366	2	385	6.0e-69	254	COG1027	Aspartate ammonia-lyase	471
650069652	450	37.73	18	449	4	442	3.0e-99	356	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
650069653	515	41.34	37	515	1	469	2.0e-125	442	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650069654	306	30.75	6	306	8	328	2.0e-42	166	COG0506	Proline dehydrogenase	391
650069655	580	39.96	60	580	53	559	3.0e-125	442	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
650069661	323	29.19	1	322	4	311	2.0e-39	156	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650069663	368	40.33	1	357	1	328	2.0e-71	262	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
650069665	271	21.03	39	270	33	258	1.0e-11	64	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
650069666	343	37.46	17	321	4	292	7.0e-73	267	COG1131	ABC-type multidrug transport system, ATPase component	293
650069667	318	44.81	2	307	3	307	2.0e-83	302	COG4189	Predicted transcriptional regulator	308
650069668	465	39.81	31	323	2	313	3.0e-64	239	COG3940	Beta-xylosidase, GH43 family	324
650069670	332	21.56	15	330	13	306	1.0e-29	123	COG2017	Galactose mutarotase or related enzyme	308
650069672	311	28.47	21	310	8	281	3.0e-43	169	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069673	323	47.74	16	323	1	309	4.0e-90	324	COG4209	ABC-type polysaccharide transport system, permease component	309
650069674	579	21.41	102	434	30	351	4.0e-16	80.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069675	232	25.17	1	226	42	314	7.0e-24	104	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
650069676	318	41.67	7	317	5	309	1.0e-79	289	COG4209	ABC-type polysaccharide transport system, permease component	309
650069677	309	30.64	16	308	5	281	7.0e-40	158	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069678	587	24.12	245	576	127	453	3.0e-34	140	COG2972	Sensor histidine kinase YesM	456
650069680	506	15.98	8	362	2	349	6.0e-13	69.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069682	337	34.57	1	336	1	349	6.0e-66	244	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650069683	313	29.65	1	295	1	310	6.0e-47	181	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650069684	284	30.29	2	274	11	278	2.0e-45	176	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
650069685	292	34.21	175	288	8	121	1.0e-22	100	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650069686	149	32.11	38	146	16	123	1.0e-08	53	COG1846	DNA-binding transcriptional regulator, MarR family	126
650069689	112	20.2	16	109	28	125	2.0e-03	34.6	COG5649	Uncharacterized protein	132
650069690	165	31.17	8	160	1	149	5.0e-24	104	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
650069695	157	60.93	1	151	1	151	6.0e-54	203	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
650069698	199	47.24	1	199	3	196	3.0e-47	181	COG0237	Dephospho-CoA kinase	201
650069699	247	21.62	4	221	2	190	2.0e-11	62.9	COG1971	Putative Mn2+ efflux pump MntP	190
650069700	278	49.28	1	274	1	273	3.0e-94	338	COG0266	Formamidopyrimidine-DNA glycosylase	273
650069701	219	35.94	4	219	10	226	5.0e-37	147	COG0704	Phosphate uptake regulator	240
650069702	251	68.53	1	251	4	253	3.0e-123	434	COG1117	ABC-type phosphate transport system, ATPase component	253
650069703	291	41.4	9	289	6	290	1.0e-61	230	COG0581	ABC-type phosphate transport system, permease component	292
650069704	244	47.81	2	244	62	310	3.0e-60	225	COG0573	ABC-type phosphate transport system, permease component	310
650069705	332	29.7	4	323	1	318	5.0e-54	204	COG0226	ABC-type phosphate transport system, periplasmic component	318
650069707	239	45.26	2	231	4	229	5.0e-63	234	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650069708	604	34.26	140	601	1	454	1.0e-76	281	COG5002	Signal transduction histidine kinase	459
650069709	323	23.78	13	318	12	311	3.0e-24	106	COG0385	Predicted Na+-dependent transporter	319
650069711	288	38	40	283	1	249	1.0e-59	223	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650069714	313	46.13	6	311	1	307	2.0e-95	342	COG0039	Malate/lactate dehydrogenase	313
650069715	430	65.64	11	430	2	406	0.0e+00	601	COG0538	Isocitrate dehydrogenase	407
650069716	370	52.24	1	370	14	390	7.0e-126	443	COG0372	Citrate synthase	390
650069718	372	25.48	3	362	7	345	3.0e-27	116	COG0628	Predicted PurR-regulated permease PerM	355
650069719	130	40.35	1	114	1	114	8.0e-20	89.5	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
650069720	169	32.9	8	161	1	135	1.0e-24	106	COG0824	Acyl-CoA thioesterase FadM	137
650069721	475	60.13	1	471	4	477	0.0e+00	631	COG0469	Pyruvate kinase	477
650069722	330	60.63	1	315	1	315	7.0e-129	453	COG0825	Acetyl-CoA carboxylase alpha subunit	317
650069723	297	62.36	25	292	12	282	2.0e-106	378	COG0777	Acetyl-CoA carboxylase beta subunit	294
650069725	164	30.32	6	151	6	160	2.0e-27	115	COG1267	Phosphatidylglycerophosphatase A	160
650069727	1143	53.64	1	1076	1	1060	0.0e+00	1299	COG0587	DNA polymerase III, alpha subunit	1139
650069731	444	47.24	9	442	2	432	0.0e+00	468	COG4109	Predicted transcriptional regulator containing CBS domains	432
650069733	115	33.33	1	111	3	113	2.0e-14	71.4	COG3679	Cell fate regulator YlbF, YheA/YmcA/DUF963 family (controls sporulation, competence, biofilm development)	118
650069734	388	27.23	7	386	7	375	4.0e-47	182	COG4399	Uncharacterized membrane protein YheB, UPF0754 family	376
650069735	464	16.57	127	457	19	313	1.0e-07	51.5	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
650069736	378	17.08	11	360	4	310	9.0e-05	41.9	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
650069740	402	19.83	28	358	22	314	2.0e-10	60.4	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
650069741	228	27.19	12	223	6	216	6.0e-25	107	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
650069745	189	48.24	1	189	1	199	1.0e-63	235	COG3546	Mn-containing catalase (includes spore coat protein CotJC)	277
650069748	343	25.7	6	327	20	332	4.0e-20	92.7	COG0628	Predicted PurR-regulated permease PerM	355
650069749	441	42.66	9	439	2	426	8.0e-100	357	COG1253	Hemolysin or related protein, contains CBS domains	429
650069750	753	26.27	8	731	1	750	3.0e-82	300	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
650069751	353	31.37	7	316	25	344	8.0e-51	194	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
650069752	274	43.64	1	274	4	269	2.0e-55	209	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
650069753	477	24.74	9	457	26	491	4.0e-55	209	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
650069754	245	29.76	4	84	1	84	1.0e-09	57.2	COG1977	Molybdopterin converting factor, small subunit	84
650069754	245	40.31	104	231	8	136	3.0e-38	151	COG0314	Molybdopterin synthase catalytic subunit	149
650069755	348	31.79	5	327	30	344	1.0e-48	187	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
650069756	465	48.51	33	463	1	412	0.0e+00	472	COG0719	Fe-S cluster assembly scaffold protein SufB	412
650069757	139	50	1	136	1	138	3.0e-40	157	COG0822	NifU homolog involved in Fe-S cluster formation	150
650069758	406	58.44	2	395	5	399	0.0e+00	516	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
650069759	434	33.25	14	431	2	410	1.0e-91	330	COG0719	Fe-S cluster assembly scaffold protein SufB	412
650069760	260	64.63	7	251	6	249	1.0e-101	362	COG0396	Fe-S cluster assembly ATPase SufC	251
650069761	158	44.3	1	158	1	156	3.0e-44	170	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
650069762	407	44.04	24	401	28	407	2.0e-110	392	COG4857	5-Methylthioribose kinase, methionine salvage pathway	408
650069763	359	57.35	15	359	3	345	9.0e-125	440	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
650069764	100	39.39	1	99	1	95	2.0e-22	96.9	COG3377	Uncharacterized protein YunC, DUF1805 family	95
650069766	126	48.41	1	126	1	124	7.0e-22	96	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
650069768	386	34.6	9	385	4	422	9.0e-110	390	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
650069770	730	33.68	9	378	12	379	9.0e-63	235	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
650069771	278	42.45	4	278	12	285	3.0e-68	251	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
650069772	219	40.35	3	218	2	228	5.0e-52	197	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650069773	466	29.04	134	463	15	334	5.0e-35	142	COG0642	Signal transduction histidine kinase	336
650069775	337	26.55	11	334	1	314	8.0e-39	154	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650069776	539	24.74	250	532	36	312	1.0e-27	118	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650069777	112	18.38	1	110	1	136	3.0e-04	37.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650069778	254	39.37	4	251	3	249	7.0e-45	174	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650069779	459	47.66	32	459	1	411	0.0e+00	515	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
650069781	244	22.03	40	143	26	136	5.0e-04	38.4	COG4642	Uncharacterized conserved protein	139
650069783	468	36.1	3	399	1	397	6.0e-67	248	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
650069784	130	17.74	7	130	5	119	2.0e-04	37.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650069785	253	43.31	5	251	1	251	1.0e-46	180	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650069787	284	34.31	5	106	20	121	1.0e-18	87.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650069789	875	27.24	13	867	6	890	2.0e-97	351	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
650069790	167	31.65	8	161	2	154	5.0e-15	74.2	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
650069793	396	57.43	1	396	1	397	0.0e+00	533	COG3007	Trans-2-enoyl-CoA reductase	398
650069794	249	42.13	1	246	2	251	1.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650069795	299	22.77	1	299	1	292	6.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
650069799	165	26.21	17	159	2	138	1.0e-06	46	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650069800	127	24.56	1	111	8	121	5.0e-03	33.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650069801	151	35.48	22	144	1	124	3.0e-12	64.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
650069803	349	38.72	1	346	2	348	1.0e-71	263	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650069804	342	34.53	7	331	1	328	3.0e-63	235	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650069805	434	42.21	3	434	2	442	3.0e-128	452	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
650069806	330	30.16	1	299	4	290	6.0e-30	125	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
650069807	297	30.79	1	296	1	281	1.0e-45	176	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069808	317	52.32	14	315	8	306	4.0e-94	338	COG4209	ABC-type polysaccharide transport system, permease component	309
650069809	292	29.2	180	292	11	123	1.0e-22	100	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650069811	285	39.6	180	280	22	122	5.0e-20	91.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650069817	117	38.05	5	117	1	113	2.0e-15	74.5	COG1695	DNA-binding transcriptional regulator, PadR family	138
650069818	177	22.94	7	174	27	183	2.0e-12	65.3	COG3216	Uncharacterized conserved protein, DUF2062 family	184
650069823	335	26.73	10	334	3	329	2.0e-40	159	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650069824	325	43.46	12	289	5	286	8.0e-70	257	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
650069825	286	38.6	1	227	1	224	8.0e-49	187	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
650069827	320	31.53	9	311	1	306	3.0e-46	179	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650069828	222	43.84	1	217	1	211	1.0e-56	213	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
650069830	284	25.99	25	247	3	215	4.0e-26	112	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
650069833	478	48.28	198	312	3	118	1.0e-35	145	COG1445	Phosphotransferase system fructose-specific component IIB	122
650069834	303	46.43	1	302	1	308	1.0e-95	342	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
650069836	285	37.94	4	284	2	282	5.0e-67	248	COG1307	Fatty acid-binding protein DegV (function unknown)	282
650069838	324	52.71	1	319	1	331	3.0e-109	388	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
650069839	268	41.22	9	268	6	267	2.0e-69	255	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
650069842	324	23	9	320	9	300	8.0e-35	141	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
650069843	598	23.95	8	597	5	616	1.0e-64	241	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
650069844	463	35.61	1	463	7	495	0.0e+00	482	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
650069845	631	41.37	1	631	1	648	0.0e+00	658	COG2766	Predicted Ser/Thr protein kinase	649
650069846	244	33.64	9	224	42	220	4.0e-28	118	COG5482	Uncharacterized protein	229
650069849	218	29.65	6	203	2	200	3.0e-23	101	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650069854	154	58.06	1	154	1	155	4.0e-60	223	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
650069856	362	50.56	4	359	5	362	9.0e-121	426	COG1932	Phosphoserine aminotransferase	365
650069858	278	31.07	5	277	8	281	5.0e-39	154	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069859	297	39.52	9	296	8	293	1.0e-49	190	COG1175	ABC-type sugar transport system, permease component	295
650069860	474	46.35	1	474	1	443	0.0e+00	509	COG0174	Glutamine synthetase	443
650069861	351	56.89	59	336	5	286	1.0e-101	363	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
650069862	598	22.75	124	588	20	456	6.0e-42	166	COG2972	Sensor histidine kinase YesM	456
650069863	524	26.07	1	523	1	474	1.0e-55	210	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650069864	554	20.65	5	398	1	350	7.0e-19	89.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650069865	298	31.19	9	297	8	281	2.0e-44	173	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650069866	318	47.71	11	316	4	306	3.0e-92	332	COG4209	ABC-type polysaccharide transport system, permease component	309
650069867	298	42.24	1	273	20	288	5.0e-77	281	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
650069868	483	32.46	141	483	20	336	2.0e-45	176	COG0642	Signal transduction histidine kinase	336
650069869	228	47.81	4	227	2	228	8.0e-62	230	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650069870	550	41.58	249	535	62	340	9.0e-57	215	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
650069871	217	42.25	4	215	1	209	3.0e-55	208	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650069872	365	29.07	3	334	24	365	5.0e-48	185	COG4585	Signal transduction histidine kinase	365
650069875	247	37.07	97	212	4	109	2.0e-23	103	COG3584	3D (Asp-Asp-Asp) domain	109
650069876	645	55.04	36	640	2	580	0.0e+00	745	COG0441	Threonyl-tRNA synthetase	589
650069878	377	39.84	2	364	6	367	2.0e-101	362	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
650069879	413	49.87	28	407	4	394	0.0e+00	476	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
650069880	386	49.36	1	382	1	393	0.0e+00	466	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
650069881	305	66.11	1	301	1	301	0.0e+00	488	COG1897	Homoserine trans-succinylase	307
650069883	311	34.23	21	311	26	322	1.0e-55	210	COG0598	Mg2+ and Co2+ transporter CorA	322
650069885	227	47.25	4	221	2	219	9.0e-56	210	COG4149	ABC-type molybdate transport system, permease component	225
650069886	279	43.46	16	274	9	256	8.0e-57	214	COG0725	ABC-type molybdate transport system, periplasmic component	258
650069887	296	43.14	1	292	5	299	1.0e-70	260	COG0258	5'-3' exonuclease	310
650069888	358	36.31	8	328	2	289	3.0e-68	252	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
650069889	186	51.89	1	184	5	184	8.0e-56	210	COG2096	Cob(I)alamin adenosyltransferase	184
650069891	166	32.21	1	149	3	149	3.0e-18	84.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650069894	408	25.96	27	402	2	380	3.0e-44	173	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650069897	139	31.58	7	139	3	132	6.0e-22	96.8	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
650069898	789	46.12	3	788	1	753	0.0e+00	624	COG1193	dsDNA-specific endonuclease/ATPase MutS2	753
650069902	816	46.65	150	815	1	650	0.0e+00	622	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
650069903	344	53.62	1	340	2	335	7.0e-129	453	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
650069904	627	35.84	3	569	2	529	2.0e-120	426	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650069914	500	42.89	38	500	37	484	1.0e-122	433	COG0260	Leucyl aminopeptidase	485
650069915	373	26.69	28	366	12	353	6.0e-39	155	COG3852	Signal transduction histidine kinase, nitrogen specific	363
650069917	179	52.27	5	176	4	178	5.0e-64	237	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
650069918	358	55.15	4	358	3	346	2.0e-119	422	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
650069920	327	43.6	2	322	1	316	2.0e-81	295	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650069921	512	49.15	2	410	1	409	1.0e-117	417	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
650069922	330	68.58	1	330	1	331	0.0e+00	535	COG0059	Ketol-acid reductoisomerase	338
650069923	161	57.5	1	160	1	160	4.0e-46	177	COG0440	Acetolactate synthase, small subunit	163
650069924	580	54.15	24	575	2	549	0.0e+00	662	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650069927	119	61.86	1	118	1	118	5.0e-40	156	COG0292	Ribosomal protein L20	118
650069928	66	50	1	62	1	62	3.0e-08	50.2	COG0291	Ribosomal protein L35	65
650069929	164	58.54	1	164	11	174	1.0e-60	225	COG0290	Translation initiation factor IF-3	176
650069930	412	21.58	4	405	16	425	4.0e-32	132	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650069931	369	22.99	2	366	4	355	9.0e-38	151	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
650069932	237	33.48	1	218	10	223	4.0e-42	164	COG0220	tRNA G46 methylase TrmB	227
650069935	322	37.85	5	322	2	311	3.0e-69	255	COG1482	Mannose-6-phosphate isomerase, class I	312
650069936	320	25.41	11	309	17	298	2.0e-40	159	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
650069938	587	22.57	8	397	23	432	6.0e-41	162	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
650069939	261	31.86	2	114	15	127	6.0e-18	84.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650069941	120	18.52	7	117	6	138	1.0e-05	42.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650069942	271	39.78	8	187	1	135	6.0e-32	131	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
650069944	676	28.97	30	381	5	359	1.0e-46	181	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650069946	268	27.4	14	226	4	210	5.0e-16	78.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650069950	284	44.84	7	257	7	255	3.0e-68	252	COG2514	Catechol-2,3-dioxygenase	265
650069951	148	26.85	1	147	1	144	3.0e-19	88.1	COG1959	DNA-binding transcriptional regulator, IscR family	150
650069955	888	31.12	165	505	1	336	2.0e-40	161	COG0642	Signal transduction histidine kinase	336
650069958	385	28.07	1	374	1	361	6.0e-60	224	COG3947	Two-component response regulator, SAPR family, consists of REC, wHTH and BTAD domains	361
650069960	154	22.08	1	150	7	158	2.0e-08	51.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650069961	191	31.89	10	187	1	185	1.0e-22	99.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650069962	485	34.48	21	480	4	454	9.0e-98	351	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650069963	166	35.4	5	164	2	162	1.0e-35	142	COG1247	L-amino acid N-acyltransferase YncA	169
650069964	362	42.13	1	362	10	384	1.0e-87	316	COG0006	Xaa-Pro aminopeptidase	384
650069965	464	58.15	1	454	1	454	0.0e+00	534	COG1823	L-cystine uptake protein TcyP, sodium:dicarboxylate symporter family	458
650069966	273	33.33	4	273	1	246	2.0e-30	126	COG0368	Cobalamin synthase	246
650069967	192	51.67	7	186	3	174	1.0e-51	196	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
650069968	356	42.17	7	356	1	338	5.0e-78	284	COG2038	NaMN:DMB phosphoribosyltransferase	347
650069969	261	39.92	1	253	2	254	4.0e-73	268	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
650069970	310	47.18	9	306	34	334	5.0e-63	234	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
650069971	335	28.28	8	335	2	319	3.0e-37	149	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650069973	246	27.71	3	245	1	200	1.0e-23	103	COG0406	Broad specificity phosphatase PhoE	208
650069974	325	43.3	1	320	3	320	4.0e-74	272	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
650069975	251	32.72	35	251	1	200	1.0e-31	130	COG1865	Adenosylcobinamide amidohydrolase	200
650069976	371	34.29	28	369	20	355	3.0e-67	249	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
650069977	334	42.46	1	245	1	248	6.0e-55	207	COG0095	Lipoate-protein ligase A	248
650069979	300	22	1	297	2	292	4.0e-05	42.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
650069980	268	33.33	2	267	1	264	1.0e-48	186	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
650069981	253	33.67	122	216	1	98	9.0e-15	74	COG0789	DNA-binding transcriptional regulator, MerR family	124
650069982	261	23.32	4	237	2	240	2.0e-18	86.3	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
650069985	426	33.95	56	426	35	406	4.0e-67	249	COG4826	Serine protease inhibitor	410
650069986	205	24.46	5	185	4	186	4.0e-22	98.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650069987	352	34.87	7	348	3	343	2.0e-77	282	COG1613	ABC-type sulfate transport system, periplasmic component	348
650069988	265	40.91	2	265	20	280	1.0e-59	222	COG4208	ABC-type sulfate transport system, permease component	287
650069989	271	44.57	14	271	15	272	6.0e-55	207	COG0555	ABC-type sulfate transport system, permease component	274
650069990	133	44.2	1	132	2	137	6.0e-38	149	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
650069991	197	23.53	1	186	3	189	2.0e-13	69.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650069992	210	40.39	2	202	1	203	6.0e-49	187	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
650069993	451	37.42	5	451	4	446	4.0e-123	435	COG0166	Glucose-6-phosphate isomerase	446
650069994	298	48.6	2	286	1	286	4.0e-76	278	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650069996	105	43.33	13	102	4	93	1.0e-20	91.6	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
650069997	673	61.38	6	673	2	662	0.0e+00	1013	COG0021	Transketolase	663
650070001	329	41.85	12	327	12	327	5.0e-65	241	COG0714	MoxR-like ATPase	329
650070004	309	39.41	1	305	4	293	1.0e-72	266	COG1131	ABC-type multidrug transport system, ATPase component	293
650070005	799	21.58	146	346	24	247	5.0e-03	36.9	COG5426	Uncharacterized membrane protein	254
650070006	299	57.04	17	299	5	287	9.0e-118	416	COG0788	Formyltetrahydrofolate hydrolase	287
650070007	373	39.65	1	282	1	272	5.0e-77	281	COG0648	Endonuclease IV	280
650070019	292	39.79	6	292	8	290	4.0e-63	235	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
650070025	290	21.31	1	287	3	275	2.0e-11	63.4	COG4965	Flp pilus assembly protein TadB	309
650070026	285	23.71	58	285	87	309	3.0e-23	102	COG4965	Flp pilus assembly protein TadB	309
650070027	415	47.94	38	377	21	355	2.0e-95	343	COG4962	Pilus assembly protein, ATPase of CpaF family	355
650070028	383	16.36	129	342	4	216	5.0e-07	49.4	COG1192	Cellulose biosynthesis protein BcsQ	259
650070030	472	42.41	23	467	3	440	4.0e-113	402	COG3182	Uncharacterized iron-regulated membrane protein	442
650070032	141	50	13	140	10	137	3.0e-31	127	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
650070034	80	41.89	7	80	1	68	7.0e-13	65.4	COG3478	Predicted nucleic-acid-binding protein, contains Zn-ribbon domain	68
650070035	139	50	1	139	4	143	3.0e-40	157	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
650070037	120	24.11	3	113	1	112	7.0e-04	36.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
650070039	529	35.23	273	528	6	259	3.0e-44	173	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
650070040	339	41.79	7	339	3	331	3.0e-56	212	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
650070041	335	36.28	10	331	6	331	2.0e-48	186	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
650070042	336	28.71	39	334	16	312	6.0e-34	138	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650070043	555	36.79	187	292	22	127	4.0e-21	96.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650070050	165	38.22	4	156	1	152	4.0e-36	144	COG3091	Predicted Zn-dependent metalloprotease, SprT family	156
650070054	185	22.22	4	181	26	194	1.0e-15	76.3	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
650070055	147	17.14	1	130	1	137	7.0e-06	43.3	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
650070056	737	54.78	16	737	3	733	0.0e+00	870	COG2183	Transcriptional accessory protein Tex/SPT6	780
650070058	116	45.13	1	113	1	112	1.0e-27	114	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
650070060	395	43.8	4	380	1	360	3.0e-109	388	COG0787	Alanine racemase	360
650070066	189	30.06	11	183	1	173	3.0e-33	134	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
650070067	400	59.64	1	391	2	386	0.0e+00	487	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
650070068	277	60.87	2	277	9	284	7.0e-92	330	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
650070072	325	37.69	2	325	1	329	4.0e-73	268	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650070076	276	61.68	1	274	1	274	6.0e-96	343	COG5564	Predicted TIM-barrel enzyme	276
650070077	403	44.8	1	402	2	400	6.0e-105	374	COG5441	Uncharacterized protein, UPF0261 family	401
650070078	401	28.93	276	396	2	122	4.0e-22	99.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650070078	401	44.12	4	274	5	275	3.0e-67	249	COG5564	Predicted TIM-barrel enzyme	276
650070079	211	30.11	6	175	1	172	4.0e-19	88.2	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
650070080	270	38.75	3	270	2	267	5.0e-54	204	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
650070097	423	34.68	6	372	1	354	4.0e-72	265	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
650070098	309	35.86	6	293	1	275	3.0e-63	235	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
650070102	236	55.41	1	231	1	230	6.0e-81	293	COG1794	Aspartate/glutamate racemase	230
650070117	162	20.99	1	160	5	155	5.0e-05	40.7	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650070123	542	49.64	1	530	2	523	0.0e+00	497	COG0459	Chaperonin GroEL (HSP60 family)	524
650070124	93	65.96	1	93	2	95	1.0e-29	121	COG0234	Co-chaperonin GroES (HSP10)	96
650070125	259	35.57	1	248	1	253	7.0e-49	187	COG0805	Sec-independent protein secretion pathway component TatC	255
650070126	78	33.78	1	74	1	74	2.0e-09	53.8	COG1826	Sec-independent protein translocase protein TatA	94
650070127	163	45.21	4	148	9	152	4.0e-34	137	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
650070128	158	61.54	1	156	2	157	5.0e-59	220	COG0315	Molybdenum cofactor biosynthesis enzyme	157
650070129	220	34.55	14	204	5	186	1.0e-35	143	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
650070130	650	44.1	1	538	2	529	0.0e+00	555	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650070131	507	47.36	6	414	1	409	2.0e-112	400	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
650070132	347	50.75	12	342	2	335	2.0e-121	429	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
650070133	174	30.18	11	162	9	177	2.0e-18	85.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650070134	263	31.45	13	258	4	219	1.0e-36	147	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
650070135	156	48.3	1	145	3	149	2.0e-40	158	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
650070138	309	38.25	1	281	3	278	2.0e-71	262	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
650070140	305	37.14	9	279	2	280	1.0e-61	230	COG3285	Eukaryotic-type DNA primase	299
650070141	362	36.88	4	263	8	252	4.0e-51	195	COG1533	DNA repair photolyase	297
650070142	305	46.81	25	302	7	288	3.0e-63	235	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
650070143	476	36.48	39	476	1	438	3.0e-78	286	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
650070145	137	33.33	12	119	22	129	6.0e-17	80	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
650070146	257	19.64	46	255	54	277	1.0e-03	37.4	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
650070147	305	38	5	300	3	293	1.0e-67	250	COG1131	ABC-type multidrug transport system, ATPase component	293
650070149	312	27.85	1	312	1	296	8.0e-58	217	COG1316	Anionic cell wall polymer biosynthesis enzyme,  LytR-Cps2A-Psr (LCP) family	307
650070150	182	25.49	12	161	1	133	1.0e-08	53.4	COG5652	VanZ like family protein (function unknown)	148
650070151	454	31.2	1	315	2	331	2.0e-54	206	COG0836	Mannose-1-phosphate guanylyltransferase	333
650070152	410	19.51	5	410	3	377	5.0e-14	72.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650070153	429	18.43	27	383	19	377	6.0e-03	35.9	COG3307	O-antigen ligase	424
650070156	266	20.31	15	266	5	252	4.0e-10	59	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650070157	455	21.34	2	418	14	413	6.0e-17	82.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
650070158	332	55.81	1	320	2	345	0.0e+00	484	COG1089	GDP-D-mannose dehydratase	345
650070159	323	28.75	12	312	2	310	4.0e-45	175	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650070160	235	55.45	36	235	36	226	2.0e-60	225	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
650070161	297	61.17	1	291	1	290	6.0e-123	433	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
650070162	253	34.84	2	221	4	222	7.0e-38	150	COG3944	Capsular polysaccharide biosynthesis protein	226
650070164	726	41.07	153	712	16	567	0.0e+00	480	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650070170	229	41	13	209	29	227	6.0e-47	180	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
650070172	122	35.71	6	61	5	60	6.0e-07	46.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
650070174	1531	60.12	711	1200	1	483	0.0e+00	661	COG0069	Glutamate synthase domain 2	485
650070175	755	33.93	4	752	1	776	2.0e-116	413	COG1511	Uncharacterized membrane protein YhgE, phage infection protein (PIP) family	780
650070176	193	26.04	1	191	8	195	2.0e-10	58.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650070177	446	23.48	1	322	2	308	8.0e-36	145	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
650070178	227	31.02	1	227	7	250	6.0e-37	147	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
650070180	189	30	11	189	2	178	6.0e-30	123	COG1514	2'-5' RNA ligase	180
650070181	317	39.86	31	309	34	314	9.0e-76	277	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650070184	368	22.01	12	366	2	330	7.0e-33	134	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650070185	471	30.89	7	463	17	412	4.0e-69	255	COG0232	dGTP triphosphohydrolase	412
650070187	261	47.97	6	153	46	189	2.0e-42	165	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
650070188	150	32.31	8	137	4	133	1.0e-30	125	COG4824	Phage-related holin (Lysis protein)	133
650070196	239	14.98	22	239	40	262	6.0e-06	44.9	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
650070207	384	25.59	9	384	3	352	1.0e-34	141	COG3299	Uncharacterized phage protein gp47/JayE	353
650070223	198	21	1	189	4	203	2.0e-13	69.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
650070224	119	44.76	1	105	2	106	2.0e-23	100	COG2076	Multidrug transporter EmrE and related cation transporters	106
650070225	189	24.21	2	189	14	201	2.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650070226	268	28.63	10	250	11	245	1.0e-21	97	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
650070227	209	41.75	13	199	1	192	2.0e-32	132	COG4721	ABC-type thiamine/hydroxymethylpyrimidine transport system, permease component	192
650070228	267	30.08	5	256	2	239	2.0e-41	162	COG0688	Phosphatidylserine decarboxylase	239
650070229	283	36.69	5	249	4	238	8.0e-40	157	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650070232	487	37.03	17	484	5	456	3.0e-95	342	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650070233	204	25.61	1	162	3	159	6.0e-20	90.8	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
650070234	432	23.1	21	430	1	393	5.0e-36	145	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650070235	404	23.69	1	398	1	375	1.0e-30	127	COG4473	Predicted ABC-type exoprotein transport system, permease component	379
650070238	448	34.43	1	448	26	481	3.0e-92	332	COG0513	Superfamily II DNA and RNA helicase	513
650070239	294	29.83	3	293	1	287	1.0e-40	160	COG0583	DNA-binding transcriptional regulator, LysR family	297
650070240	427	44.99	1	426	1	425	0.0e+00	504	COG0104	Adenylosuccinate synthase	430
650070241	249	19.23	12	239	25	282	7.0e-10	57.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650070242	289	27.93	1	288	28	309	7.0e-44	170	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650070244	239	33.33	2	239	22	263	4.0e-57	214	COG0300	Short-chain dehydrogenase	265
650070245	152	33.11	1	151	1	150	3.0e-25	108	COG1406	Chemotaxis protein CheX, a CheY~P-specific phosphatase	153
650070246	300	28.08	1	289	1	288	8.0e-43	167	COG0583	DNA-binding transcriptional regulator, LysR family	297
650070247	269	25.7	1	249	1	213	2.0e-25	109	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
650070249	302	37.99	42	301	10	284	1.0e-46	180	COG1408	Predicted phosphohydrolase, MPP superfamily	284
650070250	459	33.94	5	435	36	469	2.0e-95	343	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650070252	266	37.04	1	265	6	244	4.0e-45	175	COG2746	Aminoglycoside N3'-acetyltransferase	251
650070253	254	36.36	9	249	1	233	1.0e-64	240	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
650070254	580	41.75	4	566	8	561	0.0e+00	534	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
650070255	223	20.87	3	113	17	130	4.0e-06	45.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
650070257	305	31.13	1	300	2	297	6.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
650070258	224	40.64	4	217	1	219	2.0e-43	168	COG0569	Trk K+ transport system, NAD-binding component	225
650070259	562	17.59	320	518	26	221	6.0e-04	39.5	COG1266	Membrane protease YdiL, CAAX protease family	226
650070260	669	45.95	15	664	2	581	0.0e+00	654	COG0322	Excinuclease UvrABC, nuclease subunit	581
650070265	249	38.46	1	247	1	229	3.0e-70	258	COG3253	Chlorite dismutase	230
650070267	397	38.54	5	396	4	396	5.0e-103	368	COG1252	NADH dehydrogenase, FAD-containing subunit	405
650070274	119	47.66	1	107	4	110	8.0e-33	132	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
650070275	368	42.08	7	368	2	367	7.0e-102	364	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
650070276	352	30.73	1	352	3	384	6.0e-75	274	COG1252	NADH dehydrogenase, FAD-containing subunit	405
650070277	81	56.1	3	81	4	85	7.0e-19	85.4	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
650070278	257	34.25	1	247	3	250	7.0e-39	154	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650070279	280	55.32	1	280	1	268	3.0e-91	328	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
650070280	222	55.96	5	222	5	222	1.0e-66	246	COG2011	ABC-type methionine transport system, permease component	222
650070281	338	54.73	1	337	1	337	1.0e-120	426	COG1135	ABC-type methionine transport system, ATPase component	339
650070283	589	36.07	1	460	1	454	5.0e-117	415	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
650070284	300	26.24	3	277	42	313	1.0e-33	137	COG1612	Heme A synthase	323
650070287	541	21.76	1	504	2	479	1.0e-16	81.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
650070288	159	38.22	1	156	1	156	5.0e-19	87.2	COG2839	Uncharacterized conserved protein YqgC, DUF456 family	160
650070289	248	29.17	4	247	2	264	1.0e-49	189	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
650070290	683	25.99	20	664	13	594	6.0e-82	299	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
650070293	383	20.39	23	378	34	393	3.0e-06	46.7	COG2814	Predicted arabinose efflux permease, MFS family	394
650070294	115	25.66	3	105	11	123	1.0e-11	61.5	COG1658	5S rRNA maturation endonuclease (Ribonuclease M5), contains TOPRIM domain	127
650070295	205	25.7	5	205	1	206	3.0e-27	115	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650070296	312	43.67	13	312	1	299	1.0e-77	283	COG0109	Polyprenyltransferase (heme O synthase)	304
650070299	328	52.87	1	306	5	314	8.0e-106	377	COG0180	Tryptophanyl-tRNA synthetase	314
650070300	329	26.11	8	319	8	305	2.0e-37	149	COG2017	Galactose mutarotase or related enzyme	308
650070304	610	28.83	17	607	10	597	2.0e-116	413	COG1164	Oligoendopeptidase F	598
650070306	235	23.98	10	199	15	210	3.0e-18	85.5	COG1655	Uncharacterized protein, DUF2225 family	267
650070307	125	46.67	6	125	8	127	7.0e-31	126	COG2346	Truncated hemoglobin YjbI	133
650070308	410	19.95	1	358	1	370	2.0e-25	110	COG3314	Uncharacterized membrane protein YjiH, contains nucleoside recognition GATE domain	427
650070309	290	27.54	22	290	17	279	1.0e-44	173	COG0061	NAD kinase	281
650070310	185	46.67	1	105	12	116	7.0e-29	120	COG4470	Uncharacterized protein YutD	126
650070311	297	61.48	8	290	24	306	4.0e-128	450	COG0320	Lipoate synthase	306
650070314	114	33.33	1	100	9	110	9.0e-08	49	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650070315	140	25.53	10	140	8	148	6.0e-12	63.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
650070317	267	38.11	3	261	1	258	8.0e-55	207	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
650070318	220	41.01	4	215	1	217	1.0e-47	182	COG0569	Trk K+ transport system, NAD-binding component	225
650070320	526	56	6	526	3	527	0.0e+00	769	COG4108	Peptide chain release factor RF-3	528
650070321	515	56.17	15	499	8	480	0.0e+00	633	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
650070323	214	50.48	5	214	1	210	2.0e-59	222	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650070324	357	27.25	9	342	23	365	1.0e-48	187	COG4585	Signal transduction histidine kinase	365
650070325	214	19.81	5	212	29	233	3.0e-13	69.1	COG4758	Predicted membrane protein	235
650070326	228	37.67	1	222	1	221	2.0e-19	90	COG1842	Phage shock protein A	225
650070327	163	40	1	58	5	64	8.0e-15	73.3	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
650070328	225	25.68	1	220	1	221	4.0e-15	74.9	COG1842	Phage shock protein A	225
650070344	540	22.19	232	537	106	420	3.0e-33	136	COG3858	Spore germination protein YaaH	423
650070345	139	38.57	1	139	1	140	7.0e-38	149	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
650070346	439	17.05	102	347	35	276	1.0e-05	45.1	COG3595	Uncharacterized conserved protein YvlB, contains  DUF4097 and DUF4098 domains	318
650070348	237	41.95	12	185	10	179	4.0e-39	154	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
650070350	479	59.88	1	478	1	481	0.0e+00	729	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
650070351	485	54.56	1	484	2	475	0.0e+00	539	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650070352	95	56.84	1	95	1	95	5.0e-23	99.1	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
650070358	181	30.73	4	178	1	179	6.0e-27	114	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650070360	212	32.87	1	206	10	224	1.0e-29	123	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650070362	202	33.85	18	202	15	206	2.0e-28	118	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650070368	263	29.96	7	260	8	282	3.0e-29	122	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650070371	75	37.14	3	72	1	70	8.0e-11	58.5	COG4840	Uncharacterized protein YfkK, UPF0435 family	71
650070372	239	29.32	1	239	1	243	6.0e-21	94.6	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
650070373	334	32.61	4	323	12	332	7.0e-60	224	COG4448	L-asparaginase II	339
650070375	136	26.13	13	119	4	114	1.0e-08	52.3	COG4980	Gas vesicle protein	115
650070377	325	19.76	66	311	76	321	2.0e-28	120	COG0598	Mg2+ and Co2+ transporter CorA	322
650070378	256	32.26	6	253	3	246	2.0e-37	149	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
650070379	138	31.88	2	134	11	146	6.0e-18	83.1	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
650070380	107	23.66	14	105	9	101	3.0e-09	53.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
650070381	559	38.91	137	391	82	326	3.0e-48	186	COG0642	Signal transduction histidine kinase	336
650070382	290	30.88	26	290	3	267	2.0e-51	195	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
650070383	1219	34.77	504	781	83	333	8.0e-39	156	COG0642	Signal transduction histidine kinase	336
650070388	54	67.31	1	52	1	52	6.0e-03	32.5	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
650070390	149	32.99	33	129	20	116	4.0e-09	54.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
650070393	292	41.18	1	287	1	289	9.0e-74	270	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
650070395	541	42.13	1	529	3	529	0.0e+00	597	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650070396	343	28.41	57	313	8	234	2.0e-33	136	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
650070398	343	20.58	1	338	5	344	9.0e-37	147	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
650070399	450	38.29	4	436	2	444	5.0e-104	371	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
650070402	484	52.61	10	483	41	519	0.0e+00	578	COG0833	Amino acid permease	541
650070405	211	41.71	1	210	2	211	2.0e-47	181	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
650070406	498	41.4	1	494	3	502	0.0e+00	464	COG1070	Sugar (pentulose or hexulose) kinase	502
650070407	438	58.72	1	435	3	438	0.0e+00	685	COG2115	Xylose isomerase	438
650070408	390	34.29	77	380	1	310	6.0e-55	208	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
650070410	78	30	3	69	2	71	5.0e-10	56.1	COG0695	Glutaredoxin	80
650070411	313	54.05	1	308	3	305	2.0e-93	336	COG0492	Thioredoxin reductase	305
650070412	674	39.58	20	672	75	710	0.0e+00	571	COG2217	Cation transport ATPase	713
650070415	154	20.16	34	147	36	159	2.0e-07	48.3	COG1247	L-amino acid N-acyltransferase YncA	169
650070417	600	28	24	592	14	567	1.0e-65	244	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650070422	236	27.96	3	212	1	209	5.0e-23	101	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650070423	430	72	4	428	3	426	0.0e+00	696	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
650070424	270	41.37	11	249	6	250	3.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650070425	285	32.33	16	274	26	287	5.0e-42	165	COG1131	ABC-type multidrug transport system, ATPase component	293
650070427	229	32	3	176	1	175	2.0e-28	119	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650070428	734	13.62	1	248	1	257	1.0e-03	38.9	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
650070429	289	39.86	1	285	4	293	2.0e-70	259	COG1131	ABC-type multidrug transport system, ATPase component	293
650070430	301	40.26	1	291	1	307	2.0e-70	259	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650070431	264	26.32	1	264	3	256	6.0e-06	45	COG0730	Uncharacterized membrane protein YfcA	258
650070436	679	42.21	1	675	8	673	0.0e+00	616	COG1874	Beta-galactosidase GanA	673
650070437	428	24.6	1	428	1	431	4.0e-35	142	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650070438	279	36.65	2	278	1	281	5.0e-52	198	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650070439	293	32.2	1	293	1	294	5.0e-52	198	COG1175	ABC-type sugar transport system, permease component	295
650070442	191	23.16	3	179	1	152	9.0e-16	76.9	COG0262	Dihydrofolate reductase	167
650070443	677	41.68	1	674	8	672	0.0e+00	625	COG1874	Beta-galactosidase GanA	673
650070445	570	22.25	4	396	1	349	7.0e-15	75.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650070446	302	31.4	15	301	8	281	5.0e-44	171	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650070447	320	49.35	11	320	2	309	8.0e-100	357	COG4209	ABC-type polysaccharide transport system, permease component	309
650070448	517	30.58	1	516	1	475	5.0e-74	272	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650070450	776	38.38	8	761	1	759	0.0e+00	646	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
650070451	292	35.29	174	292	4	122	4.0e-23	101	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650070453	238	35.77	1	232	2	244	2.0e-42	165	COG3403	Uncharacterized protein YcgG, contains conserved FPC and CPF motifs	257
650070454	572	47.39	19	570	2	555	0.0e+00	612	COG0595	mRNA degradation ribonuclease J1/J2	555
650070455	404	22.03	7	347	5	338	2.0e-14	73.7	COG2814	Predicted arabinose efflux permease, MFS family	394
650070458	218	20.26	5	153	10	159	4.0e-14	71.4	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
650070459	307	51.33	38	300	1	260	1.0e-89	323	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
650070461	248	50.6	1	248	2	252	1.0e-92	332	COG0024	Methionine aminopeptidase	255
650070462	261	31.18	1	249	8	249	9.0e-37	147	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
650070465	467	30.44	18	463	5	388	2.0e-60	227	COG0247	Fe-S oxidoreductase	388
650070466	487	42.27	10	459	2	457	9.0e-99	354	COG0277	FAD/FMN-containing dehydrogenase	459
650070467	396	42.23	9	394	2	368	1.0e-80	294	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
650070468	392	45.67	9	389	29	409	1.0e-118	419	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
650070471	368	52.91	1	361	1	338	6.0e-119	420	COG3839	ABC-type sugar transport system, ATPase component	338
650070472	277	41.28	1	276	2	281	1.0e-54	206	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650070473	305	37.02	14	299	1	287	5.0e-53	201	COG1175	ABC-type sugar transport system, permease component	295
650070474	464	20.38	1	464	1	432	1.0e-26	114	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650070475	278	38.69	5	278	6	279	3.0e-64	238	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
650070476	318	29.15	1	318	4	301	5.0e-37	148	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
650070477	303	55.59	5	299	1	295	6.0e-104	370	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
650070478	288	32.42	3	249	2	242	4.0e-34	138	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650070479	321	30	1	314	3	312	4.0e-37	148	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
650070480	433	60.14	1	432	2	435	0.0e+00	580	COG0213	Thymidine phosphorylase	435
650070481	235	63.4	1	235	2	236	1.0e-99	355	COG0813	Purine-nucleoside phosphorylase	236
650070482	392	62.31	4	392	1	397	0.0e+00	575	COG1015	Phosphopentomutase	397
650070483	392	47.89	1	392	1	403	8.0e-114	404	COG1972	Nucleoside permease NupC	404
650070484	311	39.23	1	310	7	317	7.0e-83	300	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
650070486	244	56.61	4	239	3	243	4.0e-91	327	COG4813	Trehalose utilization protein	261
650070490	156	22.22	1	154	4	160	7.0e-14	70	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650070492	133	38.35	1	128	1	133	2.0e-33	134	COG1959	DNA-binding transcriptional regulator, IscR family	150
650070494	200	24.87	1	196	3	193	3.0e-10	58.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650070496	220	23.25	1	220	1	206	2.0e-26	112	COG3341	RNase HI-related protein, contains viroplasmin and RNaseH domains	225
650070499	318	27.91	1	317	5	311	2.0e-45	176	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
650070500	173	30.18	1	169	4	169	3.0e-28	118	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650070501	176	51.45	4	176	5	177	7.0e-48	183	COG4843	Uncharacterized protein YebE, UPF0316 family	179
650070502	302	19.34	42	268	8	222	2.0e-08	53.8	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
650070503	136	20.34	5	119	13	128	2.0e-04	38.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
650070504	430	35.68	18	424	27	447	5.0e-109	388	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
650070505	170	18.18	1	138	4	157	1.0e-04	39.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650070506	280	58.73	27	278	1	240	9.0e-99	353	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650070507	220	43.32	2	218	6	222	3.0e-53	201	COG0765	ABC-type amino acid transport system, permease component	222
650070508	217	43.78	1	216	7	222	9.0e-47	180	COG0765	ABC-type amino acid transport system, permease component	222
650070509	284	27.34	1	273	2	270	4.0e-26	112	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650070512	247	41.96	1	245	1	251	1.0e-49	190	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650070513	203	30.48	12	198	5	176	2.0e-26	112	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
650070514	315	31.39	7	130	2	138	2.0e-08	53.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650070515	359	30.43	14	357	9	350	4.0e-33	135	COG0628	Predicted PurR-regulated permease PerM	355
650070516	482	35.38	43	482	1	438	3.0e-86	312	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
650070517	218	35.58	1	206	1	202	9.0e-45	173	COG1182	FMN-dependent NADH-azoreductase	202
650070518	179	33.33	54	170	3	122	1.0e-09	56.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
650070519	136	59.84	6	132	3	129	1.0e-48	185	COG3607	Predicted lactoylglutathione lyase	133
650070520	248	21.82	62	171	20	126	3.0e-05	42.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
650070522	1230	38.24	330	718	37	439	3.0e-93	337	COG3325	Chitinase, GH18 family	441
650070523	389	27.79	28	351	17	345	6.0e-42	165	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650070524	110	48	9	106	4	102	3.0e-16	76.8	COG1695	DNA-binding transcriptional regulator, PadR family	138
650070525	185	23.6	7	174	5	182	8.0e-09	53.8	COG4709	Uncharacterized membrane protein	195
650070526	122	27.12	6	118	15	129	3.0e-04	37.2	COG4319	Ketosteroid isomerase homolog	137
650070538	569	28.84	80	555	8	461	1.0e-56	214	COG0471	Di- and tricarboxylate transporter	461
650070539	239	44.69	2	226	1	224	8.0e-62	230	COG4565	Response regulator of citrate/malate metabolism	224
650070540	537	38.83	13	536	6	532	4.0e-123	435	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
650070541	321	43.55	28	310	5	290	2.0e-58	220	COG1175	ABC-type sugar transport system, permease component	295
650070542	278	38.46	9	277	11	281	1.0e-57	216	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650070544	539	25.6	1	538	1	472	1.0e-67	251	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650070545	429	22.4	5	429	1	430	1.0e-33	137	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650070546	610	52.37	1	610	1	597	0.0e+00	758	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
650070548	446	48.69	3	445	8	461	1.0e-118	420	COG1109	Phosphomannomutase	464
650070549	486	25.24	1	409	1	402	1.0e-37	151	COG4856	Uncharacterized protein, YbbR domain	403
650070550	276	56.72	9	245	10	247	3.0e-70	258	COG1624	Diadenylate cyclase (c-di-AMP synthetase), DisA_N domain	247
650070551	212	15.69	11	210	4	203	2.0e-09	56.2	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
650070552	189	36.81	5	186	1	176	3.0e-33	134	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650070553	929	41.56	16	929	9	910	0.0e+00	884	COG2352	Phosphoenolpyruvate carboxylase	910
650070563	205	29.1	16	204	22	199	6.0e-14	71.1	COG1300	Uncharacterized membrane protein SpoIIM, required for sporulation	207
650070564	267	36.45	46	241	56	257	1.0e-34	140	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650070568	368	46.92	117	323	58	257	1.0e-52	200	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
650070569	257	32.72	38	243	26	227	8.0e-42	164	COG0860	N-acetylmuramoyl-L-alanine amidase	231
650070570	389	57.03	1	384	1	378	0.0e+00	512	COG2046	ATP sulfurylase (sulfate adenylyltransferase)	397
650070571	230	45.78	14	230	19	242	5.0e-58	217	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
650070572	549	17.52	49	415	52	361	4.0e-15	76.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650070573	147	29.57	17	131	2	116	5.0e-15	73.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
650070574	130	65.38	1	130	1	130	3.0e-48	183	COG0103	Ribosomal protein S9	130
650070575	145	63.45	2	145	1	145	5.0e-50	190	COG0102	Ribosomal protein L13	148
650070576	266	42.75	1	255	1	245	8.0e-74	270	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
650070577	121	61.21	3	118	7	116	1.0e-39	155	COG0203	Ribosomal protein L17	116
650070578	314	55.63	4	314	1	308	3.0e-97	348	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
650070579	131	73.23	5	131	3	129	2.0e-49	187	COG0100	Ribosomal protein S11	129
650070580	122	66.94	1	121	1	121	7.0e-42	162	COG0099	Ribosomal protein S13	121
650070581	37	68.42	1	37	1	38	7.0e-05	39	COG0257	Ribosomal protein L36	38
650070582	71	71.83	1	71	1	71	1.0e-25	107	COG0361	Translation initiation factor IF-1	75
650070584	250	55.34	1	250	2	254	9.0e-90	323	COG0024	Methionine aminopeptidase	255
650070585	214	42.25	1	213	1	178	7.0e-49	187	COG0563	Adenylate kinase or related kinase	178
650070586	432	48.97	1	431	6	432	4.0e-114	405	COG0201	Preprotein translocase subunit SecY	436
650070587	146	57.62	1	146	1	151	3.0e-37	147	COG0200	Ribosomal protein L15	152
650070588	61	58.18	4	58	1	55	2.0e-13	67.4	COG1841	Ribosomal protein L30/L7E	55
650070589	165	65.06	1	165	15	180	1.0e-58	218	COG0098	Ribosomal protein S5	181
650070590	122	58.06	1	122	2	125	6.0e-35	139	COG0256	Ribosomal protein L18	125
650070591	180	58.99	1	178	1	178	5.0e-57	213	COG0097	Ribosomal protein L6P/L9E	178
650070592	132	62.12	1	132	1	132	6.0e-54	202	COG0096	Ribosomal protein S8	132
650070593	61	59.02	1	61	1	61	1.0e-17	81.4	COG0199	Ribosomal protein S14	61
650070594	180	65.92	2	180	1	179	1.0e-74	272	COG0094	Ribosomal protein L5	180
650070595	118	66.04	13	117	1	104	6.0e-23	99.6	COG0198	Ribosomal protein L24	104
650070596	122	73.77	1	122	1	122	1.0e-47	181	COG0093	Ribosomal protein L14	122
650070597	88	56.32	1	87	1	87	5.0e-22	96.1	COG0186	Ribosomal protein S17	87
650070598	65	56.25	2	65	4	67	9.0e-12	61.8	COG0255	Ribosomal protein L29	69
650070599	144	61.38	1	143	2	146	1.0e-50	191	COG0197	Ribosomal protein L16/L10AE	146
650070600	221	67	12	213	1	203	5.0e-78	284	COG0092	Ribosomal protein S3	233
650070601	110	64.55	1	110	9	118	3.0e-34	136	COG0091	Ribosomal protein L22	120
650070602	91	62.5	1	88	1	88	1.0e-35	141	COG0185	Ribosomal protein S19	93
650070603	276	66.67	1	276	1	275	6.0e-112	397	COG0090	Ribosomal protein L2	275
650070604	97	42.11	4	96	1	94	2.0e-19	87.6	COG0089	Ribosomal protein L23	94
650070605	207	52.13	1	207	1	211	2.0e-62	231	COG0088	Ribosomal protein L4	214
650070606	207	57.55	1	207	1	212	2.0e-72	265	COG0087	Ribosomal protein L3	218
650070607	102	75.49	1	102	1	102	1.0e-38	151	COG0051	Ribosomal protein S10	104
650070612	396	78.03	1	396	1	394	0.0e+00	688	COG0050	Translation elongation factor EF-Tu, a GTPase	394
650070613	693	66.62	4	693	3	695	0.0e+00	990	COG0480	Translation elongation factor EF-G, a GTPase	697
650070614	156	61.49	2	149	1	148	2.0e-58	218	COG0049	Ribosomal protein S7	148
650070615	139	70.59	1	136	7	129	1.0e-47	181	COG0048	Ribosomal protein S12	129
650070617	1204	49.54	10	858	7	808	0.0e+00	872	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
650070618	1181	66.97	378	1151	299	1060	0.0e+00	1169	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
650070620	120	67.21	1	120	3	124	2.0e-24	104	COG0222	Ribosomal protein L7/L12	124
650070621	167	53.75	4	162	2	161	3.0e-35	141	COG0244	Ribosomal protein L10	175
650070622	230	60.35	1	226	1	227	2.0e-80	292	COG0081	Ribosomal protein L1	228
650070623	141	69.29	2	141	1	140	3.0e-51	193	COG0080	Ribosomal protein L11	141
650070624	177	56.98	1	177	1	177	9.0e-48	182	COG0250	Transcription antitermination factor NusG	178
650070625	63	40.98	1	61	13	73	8.0e-08	48.5	COG0690	Preprotein translocase subunit SecE	73
650070626	49	61.22	1	49	2	50	4.0e-10	56.4	COG0267	Ribosomal protein L33	50
650070627	214	27.32	17	210	1	176	2.0e-17	82.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650070628	172	46.15	5	171	3	170	1.0e-44	172	COG3688	Predicted RNA-binding protein containing a PIN domain	173
650070629	250	43.55	3	249	19	260	1.0e-65	243	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
650070630	147	50.77	15	144	3	132	8.0e-41	159	COG1939	23S rRNA maturation mini-RNase III	132
650070631	468	51.27	3	468	2	464	0.0e+00	616	COG0215	Cysteinyl-tRNA synthetase	464
650070632	246	59.36	17	203	2	188	2.0e-71	262	COG1045	Serine acetyltransferase	194
650070633	487	42.62	1	485	6	471	0.0e+00	483	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
650070634	162	66.03	2	157	1	156	2.0e-66	245	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
650070635	232	47.19	1	227	1	230	2.0e-68	252	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
650070636	362	56.75	1	357	1	356	4.0e-108	384	COG4956	Uncharacterized conserved protein YacL, contains PIN and TRAM domains	356
650070638	245	39.53	5	214	11	222	4.0e-40	158	COG1183	Phosphatidylserine synthase	234
650070639	358	56.9	2	349	3	349	1.0e-122	433	COG1623	Diadenylate cyclase (c-di-AMP synthetase), DNA integrity scanning protein DisA	349
650070640	455	59.91	1	455	1	455	0.0e+00	650	COG1066	Predicted ATP-dependent serine protease	456
650070641	818	57.02	5	808	1	785	0.0e+00	986	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
650070642	354	52.87	5	352	4	350	4.0e-111	395	COG3869	Protein-arginine kinase	352
650070643	174	48.82	1	168	1	168	1.0e-46	178	COG3880	Protein-arginine kinase activator protein McsA	176
650070644	153	54.67	1	150	1	150	3.0e-45	174	COG4463	Transcriptional regulator CtsR	153
650070645	238	33.48	3	228	1	228	8.0e-37	147	COG2188	DNA-binding transcriptional regulator, GntR family	236
650070646	338	26.43	4	329	1	306	5.0e-30	125	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650070648	367	27.88	4	363	12	372	7.0e-58	217	COG1921	Seryl-tRNA(Sec) selenium transferase	395
650070649	367	36.83	15	366	20	372	5.0e-80	291	COG3964	Predicted amidohydrolase	386
650070651	233	31.82	1	233	1	242	8.0e-47	180	COG1131	ABC-type multidrug transport system, ATPase component	293
650070652	121	50.43	1	116	2	118	2.0e-28	118	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
650070653	252	19.42	1	251	1	277	1.0e-04	40.9	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
650070654	375	37.7	71	371	4	293	3.0e-69	255	COG1131	ABC-type multidrug transport system, ATPase component	293
650070655	102	31.25	1	95	15	110	5.0e-05	39.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650070658	418	20.55	47	406	31	384	3.0e-11	63.3	COG2814	Predicted arabinose efflux permease, MFS family	394
650070661	670	45.51	1	669	5	667	0.0e+00	742	COG0272	NAD-dependent DNA ligase	667
650070662	776	48.46	11	646	1	644	0.0e+00	649	COG0210	Superfamily I DNA or RNA helicase	655
650070663	229	36.48	1	229	9	239	2.0e-57	215	COG1646	Heptaprenylglyceryl phosphate synthase	240
650070665	287	20.65	35	271	7	245	7.0e-10	58.3	COG0584	Glycerophosphoryl diester phosphodiesterase	257
650070667	466	46.29	240	466	1	226	1.0e-63	237	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
650070668	303	34.11	1	254	3	247	1.0e-48	187	COG1216	Glycosyltransferase, GT2 family	305
650070671	294	49.65	1	281	1	276	3.0e-91	328	COG1091	dTDP-4-dehydrorhamnose reductase	281
650070672	340	62.06	1	333	1	340	0.0e+00	535	COG1088	dTDP-D-glucose 4,6-dehydratase	340
650070673	182	55.11	1	176	1	173	3.0e-60	224	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
650070674	247	50.21	1	237	1	239	1.0e-83	302	COG1209	dTDP-glucose pyrophosphorylase	286
650070675	121	27.38	38	118	18	101	8.0e-03	32.7	COG2076	Multidrug transporter EmrE and related cation transporters	106
650070676	129	28.97	6	112	11	117	5.0e-06	43.3	COG2456	Uncharacterized protein	121
650070677	233	21	1	214	3	210	3.0e-13	69	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650070679	763	24.38	484	721	5	237	3.0e-17	84	COG1216	Glycosyltransferase, GT2 family	305
650070681	409	50.82	2	243	1	244	2.0e-83	303	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
650070682	494	30.08	229	494	3	263	3.0e-39	156	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
650070683	819	14.54	85	529	21	420	7.0e-07	50.2	COG3307	O-antigen ligase	424
650070684	290	57.44	1	288	2	290	4.0e-123	434	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
650070687	249	40.21	4	98	1	97	2.0e-15	76.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
650070688	837	44.71	11	335	7	333	5.0e-90	326	COG0826	Collagenase-like protease, PrtC family	347
650070690	365	45.51	92	247	1	156	2.0e-47	182	COG4335	3-methyladenine DNA glycosylase AlkC	167
650070691	402	21.39	8	393	15	392	3.0e-20	93.3	COG2814	Predicted arabinose efflux permease, MFS family	394
650070692	651	28.74	3	608	11	682	3.0e-117	416	COG0480	Translation elongation factor EF-G, a GTPase	697
650070694	358	35.04	8	351	2	347	4.0e-44	172	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
650070697	956	70.85	1	940	1	935	0.0e+00	1618	COG0178	Excinuclease UvrABC ATPase subunit	935
650070698	663	70.06	7	663	1	658	0.0e+00	1097	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
650070699	264	41.53	1	247	1	248	6.0e-65	240	COG1291	Flagellar motor component MotA	266
650070700	270	33.08	6	267	3	243	5.0e-47	181	COG1360	Flagellar motor protein MotB	244
650070702	779	20.8	1	381	2	385	2.0e-16	81.6	COG1668	ABC-type Na+ efflux pump, permease component	407
650070703	312	38.06	1	308	1	293	3.0e-76	278	COG1131	ABC-type multidrug transport system, ATPase component	293
650070704	395	23.73	40	388	32	365	3.0e-30	126	COG4585	Signal transduction histidine kinase	365
650070705	216	45.28	2	213	1	206	1.0e-52	199	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650070707	489	41.15	20	410	3	400	2.0e-88	319	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
650070708	422	23.61	1	422	11	418	3.0e-36	146	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
650070709	302	36.48	1	302	1	297	1.0e-62	233	COG2177	Cell division protein FtsX	297
650070710	228	62.33	1	223	1	223	2.0e-95	341	COG2884	ABC-type ATPase involved in cell division	223
650070711	478	28.52	144	430	92	371	2.0e-41	164	COG2720	Vancomycin resistance protein YoaR (function unknown), contains peptidoglycan-binding and VanW domains	376
650070713	242	24.58	27	141	8	120	7.0e-04	38	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
650070714	257	27.63	43	254	55	309	2.0e-33	136	COG0627	S-formylglutathione hydrolase FrmB	316
650070715	471	59.65	1	451	2	452	0.0e+00	664	COG0165	Argininosuccinate lyase	459
650070716	410	55.75	1	407	2	399	0.0e+00	565	COG0137	Argininosuccinate synthase	403
650070717	318	55.84	11	317	3	309	9.0e-129	453	COG0078	Ornithine carbamoyltransferase	310
650070718	406	50.76	10	402	9	401	0.0e+00	483	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
650070719	279	44.87	20	277	4	265	8.0e-67	247	COG0548	Acetylglutamate kinase	265
650070720	408	54.32	4	408	2	404	0.0e+00	509	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
650070721	351	50.43	5	351	1	349	7.0e-127	446	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
650070722	189	31.52	9	187	1	184	4.0e-29	121	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650070723	301	44.84	24	300	9	289	3.0e-64	238	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
650070724	339	63.18	96	334	1	239	6.0e-102	364	COG1186	Protein chain release factor B	239
650070725	837	58.39	1	830	1	822	0.0e+00	1080	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
650070726	188	39.09	1	110	1	110	8.0e-26	110	COG1544	Ribosome-associated translation inhibitor RaiA	110
650070727	65	65.15	1	65	2	67	6.0e-22	95.6	COG1278	Cold shock protein, CspA family	67
650070733	127	30.97	9	119	10	122	4.0e-16	76.9	COG1516	Flagellin-specific chaperone FliS	132
650070734	505	28.29	10	505	5	480	6.0e-47	182	COG1345	Flagellar capping protein FliD	483
650070737	78	53.33	1	60	1	60	4.0e-13	66.5	COG1551	sRNA-binding carbon storage regulator CsrA	73
650070738	153	41.43	3	141	2	141	4.0e-27	114	COG1699	Flagellar assembly factor FliW	146
650070740	286	23.63	1	286	12	358	1.0e-25	110	COG1344	Flagellin and related hook-associated protein FlgL	360
650070741	552	27.11	3	519	2	552	9.0e-70	258	COG1256	Flagellar hook-associated protein FlgK	552
650070743	98	26.37	1	91	4	93	4.0e-05	39.9	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
650070745	290	27.41	37	290	23	223	1.0e-24	107	COG1040	Predicted amidophosphoribosyltransferases	225
650070746	633	42.38	207	624	41	440	9.0e-106	378	COG4098	Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)	441
650070748	240	43.48	11	240	1	211	1.0e-58	219	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650070752	401	72.04	3	398	1	386	0.0e+00	686	COG0192	S-adenosylmethionine synthetase	388
650070758	374	37.58	1	315	1	311	3.0e-49	189	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
650070759	252	39.11	1	245	1	248	2.0e-67	248	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
650070762	572	29.01	42	558	3	451	1.0e-88	320	COG1109	Phosphomannomutase	464
650070763	143	53.1	1	143	3	147	3.0e-43	167	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
650070765	274	32.85	1	274	1	265	8.0e-54	203	COG4786	Flagellar basal body rod protein FlgG	265
650070766	281	27.78	1	279	13	265	2.0e-40	159	COG4786	Flagellar basal body rod protein FlgG	265
650070767	322	62.22	1	310	4	318	1.0e-116	413	COG1077	Actin-like ATPase involved in cell morphogenesis	342
650070770	360	35.34	19	353	69	394	1.0e-60	227	COG2385	Peptidoglycan hydrolase (amidase) enhancer domain	397
650070772	448	61.61	1	420	1	421	0.0e+00	612	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
650070773	84	31.58	9	84	1	76	1.0e-11	61.4	COG4836	Uncharacterized membrane protein YwzB	77
650070775	135	47.01	4	135	2	133	9.0e-29	119	COG0355	FoF1-type ATP synthase, epsilon subunit	135
650070776	466	75.05	1	466	1	465	0.0e+00	806	COG0055	FoF1-type ATP synthase, beta subunit	468
650070777	285	50.53	6	283	1	285	3.0e-90	325	COG0224	FoF1-type ATP synthase, gamma subunit	287
650070778	504	72.56	1	503	1	503	0.0e+00	852	COG0056	FoF1-type ATP synthase, alpha subunit	504
650070779	181	29.21	1	178	1	178	6.0e-30	123	COG0712	FoF1-type ATP synthase, delta subunit	178
650070780	162	34.16	1	161	2	161	5.0e-16	77.2	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
650070781	70	48.57	1	70	8	77	2.0e-06	44	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
650070782	239	32.53	2	238	17	233	2.0e-29	122	COG0356	FoF1-type ATP synthase, membrane subunit a	246
650070785	385	54.81	1	378	1	382	0.0e+00	469	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
650070786	209	63.81	1	209	1	210	4.0e-82	297	COG0035	Uracil phosphoribosyltransferase	210
650070787	416	64.08	1	411	3	412	0.0e+00	642	COG0112	Glycine/serine hydroxymethyltransferase	413
650070788	194	48.02	9	185	4	180	5.0e-54	204	COG4475	Uncharacterized protein YwlG, UPF0340 family	180
650070789	154	58.28	1	150	1	151	8.0e-53	199	COG0698	Ribose 5-phosphate isomerase RpiB	151
650070791	149	34.51	1	112	2	111	1.0e-21	95.7	COG0394	Protein-tyrosine-phosphatase	139
650070792	187	30.73	11	183	3	181	4.0e-18	84.5	COG1971	Putative Mn2+ efflux pump MntP	190
650070793	385	45.54	32	244	1	211	8.0e-62	231	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
650070795	392	34.92	6	376	12	377	1.0e-64	240	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
650070796	382	33.16	6	373	12	371	1.0e-55	210	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
650070797	296	43.01	12	296	1	277	1.0e-56	213	COG2890	Methylase of polypeptide chain release factors	280
650070798	355	61.02	1	352	5	358	0.0e+00	517	COG0216	Protein chain release factor A	363
650070799	366	61.5	1	366	1	372	0.0e+00	513	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
650070800	500	36.97	68	500	1	438	2.0e-84	306	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
650070801	198	25.44	6	174	17	179	8.0e-11	60.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650070802	113	44.34	2	104	1	106	2.0e-19	87.8	COG2076	Multidrug transporter EmrE and related cation transporters	106
650070803	104	40.38	1	104	2	105	4.0e-17	79.7	COG2076	Multidrug transporter EmrE and related cation transporters	106
650070804	317	25.58	1	172	6	177	3.0e-13	69.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650070805	1070	31.57	303	1063	245	1009	0.0e+00	539	COG0841	Multidrug efflux pump subunit AcrB	1009
650070807	334	44.01	4	334	1	322	2.0e-99	355	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
650070808	212	36.68	11	208	1	190	5.0e-37	147	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
650070811	620	31.89	75	594	6	472	2.0e-91	330	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
650070812	84	30.49	1	82	1	82	6.0e-13	65.7	COG5460	Uncharacterized conserved protein, DUF2164 family	82
650070813	182	27.96	1	182	1	186	8.0e-23	100	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650070814	219	43.41	5	209	3	205	2.0e-55	209	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
650070815	164	25	7	164	1	164	3.0e-13	68.4	COG1247	L-amino acid N-acyltransferase YncA	169
650070816	721	36.41	13	400	1	368	1.0e-79	291	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
650070817	253	27.57	21	251	39	309	6.0e-36	144	COG0627	S-formylglutathione hydrolase FrmB	316
650070818	333	40.24	2	330	1	333	3.0e-82	298	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650070819	272	45.85	2	272	5	281	9.0e-57	213	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650070820	299	39.52	6	295	4	289	3.0e-56	212	COG1175	ABC-type sugar transport system, permease component	295
650070821	414	28.84	9	414	7	433	1.0e-44	174	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650070822	421	22.35	38	391	40	380	8.0e-09	55.2	COG2807	Cyanate permease	395
650070823	555	25.14	188	551	79	407	1.0e-35	144	COG2972	Sensor histidine kinase YesM	456
650070824	524	23.66	1	521	1	473	4.0e-51	195	COG4753	Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains	475
650070825	558	19.47	71	406	36	349	9.0e-15	75.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650070826	324	49.84	16	322	5	306	6.0e-87	314	COG4209	ABC-type polysaccharide transport system, permease component	309
650070827	695	33.88	14	689	42	762	0.0e+00	501	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
650070829	291	45.77	1	256	3	261	6.0e-60	224	COG2116	Formate/nitrite transporter FocA, FNT family	265
650070830	471	33.97	16	462	1	456	2.0e-43	170	COG0531	Amino acid transporter	466